WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 Gene3D G3DSA:3.40.50.300 2 307 9.2E-71 T 28-03-2018 WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 SMART SM00382 41 220 4.7E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 220 305 2.6E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 222 287 8.4E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 Pfam PF00005 ABC transporter 32 171 3.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS06835 8129bbfe1ae771d3debc90340a88270d 307 SUPERFAMILY SSF52540 6 241 8.19E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 SUPERFAMILY SSF100934 507 602 2.75E-29 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 Pfam PF00012 Hsp70 protein 4 602 1.4E-268 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 Gene3D G3DSA:2.60.34.10 390 531 3.8E-65 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 634 37.036 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 SUPERFAMILY SSF53067 4 183 3.89E-65 T 28-03-2018 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 Gene3D G3DSA:3.30.420.40 197 366 7.5E-46 T 28-03-2018 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 SUPERFAMILY SSF100920 384 539 9.94E-62 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 469 485 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 138 158 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 198 208 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 31 43 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 54 62 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 334 350 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 3 16 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 388 407 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 PRINTS PR00301 70kDa heat shock protein signature 365 385 8.2E-81 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 2.5E-292 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 Gene3D G3DSA:3.30.420.40 1 196 1.7E-80 T 28-03-2018 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 SUPERFAMILY SSF53067 187 382 2.01E-68 T 28-03-2018 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 Gene3D G3DSA:1.20.1270.10 532 619 3.0E-20 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS14765 a91cbef877e8003cb6a10106fef9852f 638 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS18715 8ac1beafc01756e616caf5234f27f35c 309 Hamap MF_00611 Protein FdhE [fdhE]. 3 306 50.397 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 WM46_RS18715 8ac1beafc01756e616caf5234f27f35c 309 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 2 305 1.9E-153 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 WM46_RS18715 8ac1beafc01756e616caf5234f27f35c 309 SUPERFAMILY SSF144020 24 306 1.83E-99 T 28-03-2018 IPR024064 FdhE-like WM46_RS18715 8ac1beafc01756e616caf5234f27f35c 309 Gene3D G3DSA:3.90.1670.10 24 308 7.5E-103 T 28-03-2018 IPR024064 FdhE-like WM46_RS18715 8ac1beafc01756e616caf5234f27f35c 309 PIRSF PIRSF018296 1 309 5.3E-139 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 WM46_RS18715 8ac1beafc01756e616caf5234f27f35c 309 Pfam PF04216 Protein involved in formate dehydrogenase formation 22 304 1.1E-117 T 28-03-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 WM46_RS21950 af0410ab7fa9937cda8b29f63844bf86 445 Pfam PF13520 Amino acid permease 12 403 8.1E-52 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS21950 af0410ab7fa9937cda8b29f63844bf86 445 PIRSF PIRSF006060 1 434 1.1E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS00450 429df9b896e82ad3f6b197dd9c5a9e30 211 Gene3D G3DSA:3.40.50.1000 1 145 7.5E-7 T 28-03-2018 IPR023214 HAD-like domain WM46_RS00450 429df9b896e82ad3f6b197dd9c5a9e30 211 SUPERFAMILY SSF56784 6 147 5.33E-8 T 28-03-2018 IPR023214 HAD-like domain WM46_RS00450 429df9b896e82ad3f6b197dd9c5a9e30 211 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 192 6.6E-12 T 28-03-2018 WM46_RS00450 429df9b896e82ad3f6b197dd9c5a9e30 211 TIGRFAM TIGR01545 YfhB_g-proteo: HAD hydrolase, family IF 3 211 1.6E-128 T 28-03-2018 IPR006435 HAD-superfamily hydrolase, subfamily IF, YfhB KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM46_RS04230 21bbb68c9147827a68d6f1bcc5412e8e 527 Gene3D G3DSA:1.20.1250.20 2 222 7.3E-21 T 28-03-2018 WM46_RS04230 21bbb68c9147827a68d6f1bcc5412e8e 527 SUPERFAMILY SSF103473 10 444 1.01E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04230 21bbb68c9147827a68d6f1bcc5412e8e 527 Pfam PF13347 MFS/sugar transport protein 13 451 8.2E-55 T 28-03-2018 WM46_RS04230 21bbb68c9147827a68d6f1bcc5412e8e 527 Gene3D G3DSA:1.20.1250.20 232 460 1.8E-10 T 28-03-2018 WM46_RS16695 9f650de7b8ff8c0512e4d867a3cf5072 147 SUPERFAMILY SSF50475 3 136 5.1E-14 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS16695 9f650de7b8ff8c0512e4d867a3cf5072 147 Hamap MF_00764 UPF0306 protein YhbP [yhbP]. 3 140 35.465 T 28-03-2018 IPR011194 Uncharacterised protein family UPF0306 WM46_RS16695 9f650de7b8ff8c0512e4d867a3cf5072 147 Gene3D G3DSA:2.30.110.10 1 143 2.9E-13 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS16695 9f650de7b8ff8c0512e4d867a3cf5072 147 PIRSF PIRSF009554 1 145 1.5E-59 T 28-03-2018 IPR011194 Uncharacterised protein family UPF0306 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 213 255 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 SMART SM00342 176 259 7.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 SUPERFAMILY SSF46689 213 263 7.62E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 Gene3D G3DSA:1.10.10.60 213 270 6.5E-14 T 28-03-2018 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 Gene3D G3DSA:1.10.10.60 152 212 2.8E-7 T 28-03-2018 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 8.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 8.5E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 Gene3D G3DSA:2.60.120.280 20 148 6.1E-14 T 28-03-2018 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 Pfam PF12833 Helix-turn-helix domain 182 261 6.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 SUPERFAMILY SSF51215 8 143 1.2E-14 T 28-03-2018 WM46_RS17135 a0f0947d44f3108dc3c0a916f853d05a 270 Pfam PF02311 AraC-like ligand binding domain 26 133 4.4E-5 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00397 Sirohaem Fe-binding site signature 679 697 7.9E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00397 Sirohaem Fe-binding site signature 636 654 7.9E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 560 622 1.8E-10 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 679 695 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 SUPERFAMILY SSF51905 2 189 1.44E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Gene3D G3DSA:3.30.413.10 631 816 7.4E-37 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 768 2.7E-15 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 801 0.0 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 SUPERFAMILY SSF56014 633 809 7.46E-47 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 3.0E-11 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 3.0E-11 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 3.0E-11 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 105 114 3.0E-11 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Gene3D G3DSA:3.50.50.60 104 243 8.2E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PIRSF PIRSF037149 1 835 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Gene3D G3DSA:3.50.50.60 246 325 4.6E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Gene3D G3DSA:3.90.480.10 447 629 8.6E-7 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.9E-14 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 5.9E-14 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 5.9E-14 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 5.9E-14 T 28-03-2018 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 SUPERFAMILY SSF51905 144 310 1.77E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 471 1.4E-14 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Gene3D G3DSA:3.50.50.60 1 103 1.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 SUPERFAMILY SSF55124 502 627 4.25E-31 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS17725 b0bbf9259a14bae12a6fa9adb23fe96f 847 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 292 5.1E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 Gene3D G3DSA:1.10.10.10 78 194 6.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 SUPERFAMILY SSF46894 130 192 3.2E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 SMART SM00421 133 190 2.5E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 135 189 2.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 178 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 166 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11995 9ff6ab4cc7441aa4ad433a8f1f6b64fc 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 136 150 1.1E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 158 186 - T 28-03-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 Pfam PF00482 Type II secretion system (T2SS), protein F 269 388 1.9E-22 T 28-03-2018 IPR018076 Type II secretion system F domain WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 Pfam PF00482 Type II secretion system (T2SS), protein F 64 186 2.4E-29 T 28-03-2018 IPR018076 Type II secretion system F domain WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 158 186 4.0E-14 T 28-03-2018 IPR003004 GspF/PilC family WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 377 396 4.0E-14 T 28-03-2018 IPR003004 GspF/PilC family WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 59 71 4.0E-14 T 28-03-2018 IPR003004 GspF/PilC family WM46_RS14310 cf345a9c31b5f3f706a525a60c4dafb3 400 PRINTS PR00812 Bacterial general secretion pathway protein F signature 361 375 4.0E-14 T 28-03-2018 IPR003004 GspF/PilC family WM46_RS08700 211eeaac246f953b67ca2ccd0477fe3b 57 Pfam PF01783 Ribosomal L32p protein family 2 57 1.9E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08700 211eeaac246f953b67ca2ccd0477fe3b 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.2E-18 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08700 211eeaac246f953b67ca2ccd0477fe3b 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 16.352 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08700 211eeaac246f953b67ca2ccd0477fe3b 57 SUPERFAMILY SSF57829 2 55 1.53E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 Gene3D G3DSA:3.90.1150.10 310 426 2.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 3 425 6.5E-205 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 Gene3D G3DSA:3.90.1150.10 1 154 1.0E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 Gene3D G3DSA:3.40.640.10 167 309 1.4E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 107.55 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 SUPERFAMILY SSF53383 2 425 3.74E-136 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS14045 d6a1a1e51af1f3f5a9f9fe21d81844c7 426 Pfam PF00202 Aminotransferase class-III 32 395 1.4E-79 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS09360 1d9056dcab110eb6ab2ed0af0c338e85 374 SUPERFAMILY SSF55729 139 371 1.81E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS09360 1d9056dcab110eb6ab2ed0af0c338e85 374 SUPERFAMILY SSF55729 4 111 1.81E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS09360 1d9056dcab110eb6ab2ed0af0c338e85 374 Gene3D G3DSA:3.40.630.30 2 122 6.3E-4 T 28-03-2018 WM46_RS09360 1d9056dcab110eb6ab2ed0af0c338e85 374 Gene3D G3DSA:3.40.630.30 181 370 2.4E-10 T 28-03-2018 WM46_RS04440 c67e6c1c270da59df73802d3c10e8b95 112 Pfam PF10765 Protein of unknown function (DUF2591) 2 102 8.1E-17 T 28-03-2018 IPR019701 Bacteriophage P22, NinX WM46_RS17115 e6807ec5cc83f681ac62c68c1bc8ef12 67 Pfam PF07869 Protein of unknown function (DUF1656) 7 61 3.6E-20 T 28-03-2018 IPR012451 Protein of unknown function DUF1656 WM46_RS17115 e6807ec5cc83f681ac62c68c1bc8ef12 67 Hamap MF_01546 Protein AaeX [aaeX]. 1 67 24.567 T 28-03-2018 IPR012451 Protein of unknown function DUF1656 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 ProSitePatterns PS01134 FtsZ protein signature 1. 43 77 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 ProSitePatterns PS01135 FtsZ protein signature 2. 96 117 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 SUPERFAMILY SSF55307 203 319 7.33E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 SMART SM00865 206 324 3.4E-56 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 338 8.4E-142 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 172 8.1E-42 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 Gene3D G3DSA:3.40.50.1440 8 213 1.6E-42 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 Pfam PF12327 FtsZ family, C-terminal domain 221 315 2.4E-37 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 SUPERFAMILY SSF52490 12 207 2.09E-69 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 8 343 38.192 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 SMART SM00864 12 204 6.3E-111 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 Gene3D G3DSA:3.30.1330.20 214 324 1.0E-44 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 PRINTS PR00423 Cell division protein FtsZ signature 188 210 2.5E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 PRINTS PR00423 Cell division protein FtsZ signature 97 117 2.5E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 PRINTS PR00423 Cell division protein FtsZ signature 211 232 2.5E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS14355 d001cbb2fd76a7c9e6371ab174041860 383 PRINTS PR00423 Cell division protein FtsZ signature 125 146 2.5E-52 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 WM46_RS20790 ec4b3ffbbc0ebb034574d565e6d9e60e 167 SUPERFAMILY SSF46785 5 146 4.82E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20790 ec4b3ffbbc0ebb034574d565e6d9e60e 167 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 5 143 7.8E-30 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type WM46_RS20790 ec4b3ffbbc0ebb034574d565e6d9e60e 167 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 51 69 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site WM46_RS20790 ec4b3ffbbc0ebb034574d565e6d9e60e 167 Gene3D G3DSA:1.10.10.10 1 155 6.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20790 ec4b3ffbbc0ebb034574d565e6d9e60e 167 Pfam PF02082 Transcriptional regulator 4 85 1.4E-24 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 Hamap MF_01441 DNA protection during starvation protein [dps]. 1 167 48.999 T 28-03-2018 IPR023067 DNA protection during starvation protein, gammaproteobacteria GO:0016722|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 SUPERFAMILY SSF47240 10 167 3.69E-50 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 Gene3D G3DSA:1.20.1260.10 1 167 1.7E-40 T 28-03-2018 IPR012347 Ferritin-related WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 144 162 2.3E-13 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 2.3E-13 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 75 91 2.3E-13 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 ProSitePatterns PS00819 Dps protein family signature 2. 77 91 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 ProSitePatterns PS00818 Dps protein family signature 1. 51 67 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 PIRSF PIRSF005900 8 167 1.8E-43 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 WM46_RS10405 b6930f30b3240b5cc036574d44caa088 167 Pfam PF00210 Ferritin-like domain 31 166 1.2E-21 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 WM46_RS15455 a2dddc635518711b0ae48bc02e2462f5 307 Pfam PF13737 Transposase DDE domain 19 130 1.4E-43 T 28-03-2018 IPR025668 Transposase DDE domain WM46_RS23360 a2dddc635518711b0ae48bc02e2462f5 307 Pfam PF13737 Transposase DDE domain 19 130 1.4E-43 T 28-03-2018 IPR025668 Transposase DDE domain WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 134 3.8E-38 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 274 622 2.2E-80 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 150 1.4E-33 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 SUPERFAMILY SSF55804 1 149 1.57E-33 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 Gene3D G3DSA:3.40.50.2300 165 264 1.4E-32 T 28-03-2018 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 Pfam PF02378 Phosphotransferase system, EIIC 293 540 1.6E-9 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 SUPERFAMILY SSF52794 166 261 9.94E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 Gene3D G3DSA:3.40.930.10 1 159 3.7E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 168 257 2.7E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS10855 f865e0899bc0e937a780726810e1dfbe 638 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 167 245 1.0E-22 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 WM46_RS01605 6dfb2bcc0cb7f22aafde6312dd994c0d 189 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 186 4.8E-69 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 WM46_RS01605 6dfb2bcc0cb7f22aafde6312dd994c0d 189 Gene3D G3DSA:3.40.50.1950 2 189 1.4E-52 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS01605 6dfb2bcc0cb7f22aafde6312dd994c0d 189 SUPERFAMILY SSF52507 2 188 1.7E-60 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS01605 6dfb2bcc0cb7f22aafde6312dd994c0d 189 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 188 37.262 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 WM46_RS01605 6dfb2bcc0cb7f22aafde6312dd994c0d 189 Pfam PF02441 Flavoprotein 2 165 2.6E-24 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS16155 6175f1aefe1bf9411f5b35bdaa7cc3af 257 Pfam PF02535 ZIP Zinc transporter 104 246 6.0E-23 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 WM46_RS23065 9d611ed9308a4beadf2ca348e63dbc72 185 TIGRFAM TIGR01626 ytfJ_HI0045: conserved hypothetical protein YtfJ-family, TIGR01626 1 183 9.0E-91 T 28-03-2018 IPR006513 Conserved hypothetical protein CHP01626, YtfJ WM46_RS23065 9d611ed9308a4beadf2ca348e63dbc72 185 Gene3D G3DSA:3.40.30.10 19 184 3.8E-5 T 28-03-2018 WM46_RS23065 9d611ed9308a4beadf2ca348e63dbc72 185 Pfam PF09695 Bacterial protein of unknown function (YtfJ_HI0045) 24 181 1.4E-75 T 28-03-2018 IPR006513 Conserved hypothetical protein CHP01626, YtfJ WM46_RS19045 b7154d247c5ba5a2851fc7b701345997 299 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 11 273 1.1E-91 T 28-03-2018 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 WM46_RS19045 b7154d247c5ba5a2851fc7b701345997 299 SUPERFAMILY SSF103481 200 278 7.85E-9 T 28-03-2018 WM46_RS19045 b7154d247c5ba5a2851fc7b701345997 299 Pfam PF00892 EamA-like transporter family 2 128 2.3E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS19045 b7154d247c5ba5a2851fc7b701345997 299 Pfam PF00892 EamA-like transporter family 139 274 3.2E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS19045 b7154d247c5ba5a2851fc7b701345997 299 SUPERFAMILY SSF103481 35 131 2.48E-6 T 28-03-2018 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 SUPERFAMILY SSF46894 147 213 1.7E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 SMART SM00421 153 210 1.0E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 SUPERFAMILY SSF52172 6 135 7.26E-36 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 Gene3D G3DSA:3.40.50.2300 6 138 1.3E-37 T 28-03-2018 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 Gene3D G3DSA:1.10.10.10 139 215 9.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 8.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 SMART SM00448 7 120 7.2E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS05610 0e83b24da97ebbef9fa44a34b023e069 216 Pfam PF00072 Response regulator receiver domain 9 120 5.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 1.8E-6 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 Pfam PF00578 AhpC/TSA family 10 133 1.7E-32 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 SUPERFAMILY SSF52833 1 186 3.42E-53 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 PIRSF PIRSF000239 1 187 4.8E-50 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 1.2E-103 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 Gene3D G3DSA:3.30.1020.10 154 183 1.6E-9 T 28-03-2018 WM46_RS11540 24e5c3b94fec9cb633516907d20558bd 187 Gene3D G3DSA:3.40.30.10 5 153 8.8E-32 T 28-03-2018 WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 4 163 2.4E-80 T 28-03-2018 IPR014297 Dimethylsulphoxide reductase, chain B WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 Gene3D G3DSA:3.30.70.20 81 118 9.6E-21 T 28-03-2018 WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 Gene3D G3DSA:3.30.70.20 119 202 1.3E-17 T 28-03-2018 WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 Pfam PF12800 4Fe-4S binding domain 12 25 0.0027 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 Gene3D G3DSA:3.30.70.20 3 80 2.0E-18 T 28-03-2018 WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 SUPERFAMILY SSF54862 3 199 1.47E-70 T 28-03-2018 WM46_RS09915 e8c72c08ece3bd7352d2005ce858d1d7 205 Pfam PF13247 4Fe-4S dicluster domain 59 153 1.2E-28 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SMART SM01096 424 547 3.9E-75 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 710 724 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:3.30.470.20 119 403 5.5E-67 T 28-03-2018 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Pfam PF02142 MGS-like domain 957 1041 7.6E-18 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 6.4E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:3.40.50.20 539 655 1.9E-62 T 28-03-2018 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 3.4E-40 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:1.10.1030.10 404 538 3.6E-53 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:3.40.50.20 4 109 2.9E-40 T 28-03-2018 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 839 846 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SUPERFAMILY SSF56059 674 934 2.65E-105 T 28-03-2018 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SUPERFAMILY SSF56059 128 401 2.65E-110 T 28-03-2018 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SUPERFAMILY SSF52440 1 127 5.61E-50 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 674 876 4.4E-39 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.2E-77 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SMART SM00851 956 1042 2.6E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:3.40.50.1380 937 1073 5.3E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SUPERFAMILY SSF52440 557 676 1.44E-49 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SUPERFAMILY SSF48108 396 554 4.58E-53 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1063 13.187 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:3.30.470.20 746 936 5.8E-44 T 28-03-2018 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1068 13.399 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 SUPERFAMILY SSF52335 938 1071 9.03E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1053 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14665 588f32f45f9795519fef4550169b17b5 1074 Gene3D G3DSA:3.30.1490.20 656 745 1.3E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.4E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 1.4E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.4E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 Gene3D G3DSA:1.10.287.130 338 418 1.5E-7 T 28-03-2018 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 SUPERFAMILY SSF53850 43 271 4.12E-15 T 28-03-2018 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 Gene3D G3DSA:3.30.565.10 429 578 2.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 SMART SM00388 354 423 4.0E-4 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 SUPERFAMILY SSF55874 430 559 2.88E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 SMART SM00387 470 578 8.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 29 260 6.6E-32 T 28-03-2018 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 SUPERFAMILY SSF47384 344 417 4.12E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 Gene3D G3DSA:3.40.190.10 120 268 7.0E-16 T 28-03-2018 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 Pfam PF00512 His Kinase A (phospho-acceptor) domain 355 416 9.0E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS07770 05fb3e5f28e0e866eb8a8ace95705ced 590 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 475 560 4.0E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS05235 12fe4c1c998541324a7049a186005781 634 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 348 361 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 405 420 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 SUPERFAMILY SSF55785 197 296 5.93E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Pfam PF00989 PAS fold 202 303 2.3E-12 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Pfam PF01590 GAF domain 52 186 3.0E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Gene3D G3DSA:3.30.450.20 200 301 1.1E-9 T 28-03-2018 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Pfam PF02954 Bacterial regulatory protein, Fis family 584 623 1.4E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 SUPERFAMILY SSF55781 52 181 7.85E-6 T 28-03-2018 IPR029016 GAF domain-like WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Gene3D G3DSA:3.30.450.40 43 199 4.3E-6 T 28-03-2018 IPR029016 GAF domain-like WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Gene3D G3DSA:3.40.50.300 320 491 2.6E-18 T 28-03-2018 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 SUPERFAMILY SSF46689 531 626 1.02E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 SUPERFAMILY SSF52540 328 562 1.57E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05235 12fe4c1c998541324a7049a186005781 634 SMART SM00382 344 483 3.5E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Pfam PF00158 Sigma-54 interaction domain 327 485 5.7E-33 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 SMART SM00091 200 266 5.0E-5 T 28-03-2018 IPR000014 PAS domain WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Gene3D G3DSA:1.10.10.60 560 626 2.5E-16 T 28-03-2018 WM46_RS05235 12fe4c1c998541324a7049a186005781 634 Gene3D G3DSA:1.10.8.60 492 559 2.2E-13 T 28-03-2018 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 2.5E-16 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 53.158 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 Pfam PF00406 Adenylate kinase 5 186 2.7E-60 T 28-03-2018 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 PRINTS PR00094 Adenylate kinase signature 81 97 6.0E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 PRINTS PR00094 Adenylate kinase signature 4 17 6.0E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 PRINTS PR00094 Adenylate kinase signature 173 187 6.0E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 PRINTS PR00094 Adenylate kinase signature 32 46 6.0E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 PRINTS PR00094 Adenylate kinase signature 156 171 6.0E-36 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 5.0E-76 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 Gene3D G3DSA:3.40.50.300 1 214 6.5E-68 T 28-03-2018 WM46_RS12365 d28f93000e211f45465a93251ab7655d 214 SUPERFAMILY SSF52540 1 188 1.46E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 Hamap MF_01237 N-acetylneuraminate lyase [nanA]. 5 294 50.651 T 28-03-2018 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581|Reactome: R-HSA-4085001 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 5.1E-21 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.1E-21 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 5.1E-21 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 5.1E-21 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 SUPERFAMILY SSF51569 5 291 7.22E-82 T 28-03-2018 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 PIRSF PIRSF001365 1 297 3.7E-82 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 TIGRFAM TIGR00683 nanA: N-acetylneuraminate lyase 5 296 4.9E-159 T 28-03-2018 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581|Reactome: R-HSA-4085001 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 SMART SM01130 4 293 1.8E-84 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 Pfam PF00701 Dihydrodipicolinate synthetase family 5 291 5.1E-105 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 41 58 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 Gene3D G3DSA:3.20.20.70 3 297 1.1E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS17015 e74de7f33cc20603e76c69ac11bfb7d2 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 PRINTS PR00969 Pili chaperone signature 76 97 3.9E-20 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 PRINTS PR00969 Pili chaperone signature 169 184 3.9E-20 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 PRINTS PR00969 Pili chaperone signature 105 122 3.9E-20 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 PRINTS PR00969 Pili chaperone signature 132 147 3.9E-20 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 Gene3D G3DSA:2.60.40.10 154 240 1.1E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 SUPERFAMILY SSF49354 22 150 2.88E-31 T 28-03-2018 IPR008962 PapD-like WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 174 228 1.9E-10 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 Gene3D G3DSA:2.60.40.10 26 151 9.4E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 SUPERFAMILY SSF49584 144 235 2.75E-16 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24695 f97ac00bef920b54ec8eef5b9e523af7 241 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 30 150 2.2E-34 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 Gene3D G3DSA:2.30.30.60 178 228 3.5E-13 T 28-03-2018 WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 SUPERFAMILY SSF50182 162 228 3.6E-17 T 28-03-2018 IPR010920 LSM domain WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 SUPERFAMILY SSF82689 231 335 6.93E-21 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 194 228 - T 28-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 SUPERFAMILY SSF82861 79 160 1.57E-10 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 Gene3D G3DSA:3.30.70.100 230 329 1.2E-19 T 28-03-2018 WM46_RS06145 34cd94bc06eba7328496b3bba1a9119b 339 Pfam PF00924 Mechanosensitive ion channel 120 323 2.3E-60 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM46_RS17355 f465b04caaf5419306718537eed1e821 190 SUPERFAMILY SSF55821 4 187 6.1E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS17355 f465b04caaf5419306718537eed1e821 190 Gene3D G3DSA:3.90.870.10 1 188 1.1E-51 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS17355 f465b04caaf5419306718537eed1e821 190 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 7 188 40.683 T 28-03-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 WM46_RS17355 f465b04caaf5419306718537eed1e821 190 Pfam PF01300 Telomere recombination 15 190 2.1E-42 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 Pfam PF02610 L-arabinose isomerase 5 359 1.8E-179 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 303 4.0E-177 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 PIRSF PIRSF001478 1 500 2.9E-257 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 SUPERFAMILY SSF53743 1 326 4.18E-125 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 Hamap MF_00519 L-arabinose isomerase [araA]. 1 477 64.717 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 SUPERFAMILY SSF50443 329 497 7.32E-71 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal WM46_RS14520 0ad84d5237e5e541d50d224ea77407fb 500 Pfam PF11762 L-arabinose isomerase C-terminal domain 363 476 1.5E-45 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 Pfam PF00271 Helicase conserved C-terminal domain 236 339 2.8E-26 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 Gene3D G3DSA:3.40.50.300 224 453 1.4E-47 T 28-03-2018 WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 Gene3D G3DSA:3.40.50.300 7 223 2.3E-60 T 28-03-2018 WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 SUPERFAMILY SSF52540 75 361 4.2E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 Pfam PF00270 DEAD/DEAH box helicase 25 196 3.8E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 451 52.363 T 28-03-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 SMART SM00490 259 340 7.6E-32 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM46_RS10485 53c212bee34d20183d311a30f1a5d316 458 SMART SM00487 20 223 3.1E-62 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Pfam PF04546 Sigma-70, non-essential region 139 349 4.9E-75 T 28-03-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 404 417 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 376 612 1.3E-120 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 SUPERFAMILY SSF88659 453 526 8.78E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Pfam PF03979 Sigma-70 factor, region 1.1 4 81 1.4E-30 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Pfam PF04539 Sigma-70 region 3 459 534 3.5E-29 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 SUPERFAMILY SSF88946 115 447 6.02E-103 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 573 599 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 376 601 3.5E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Gene3D G3DSA:1.10.10.10 542 613 6.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Gene3D G3DSA:1.10.601.10 3 114 2.7E-14 T 28-03-2018 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Gene3D G3DSA:1.10.601.10 115 449 6.6E-108 T 28-03-2018 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Pfam PF04542 Sigma-70 region 2 380 449 1.7E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Gene3D G3DSA:1.10.10.10 450 500 7.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 613 46.937 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 PRINTS PR00046 Major sigma-70 factor signature 552 564 6.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 PRINTS PR00046 Major sigma-70 factor signature 404 417 6.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 PRINTS PR00046 Major sigma-70 factor signature 428 436 6.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 PRINTS PR00046 Major sigma-70 factor signature 573 588 6.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 PRINTS PR00046 Major sigma-70 factor signature 588 599 6.4E-31 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Pfam PF00140 Sigma-70 factor, region 1.2 98 128 1.8E-12 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 Pfam PF04545 Sigma-70, region 4 548 601 1.0E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS16310 98ce9bb33d341b90b5e672361a3794ce 614 SUPERFAMILY SSF88659 510 612 2.55E-25 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS17975 e8c6f455bd9dd91148aa35184a0bba37 110 Pfam PF00581 Rhodanese-like domain 9 98 4.0E-14 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS17975 e8c6f455bd9dd91148aa35184a0bba37 110 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 105 31.122 T 28-03-2018 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 WM46_RS17975 e8c6f455bd9dd91148aa35184a0bba37 110 SUPERFAMILY SSF52821 1 101 4.98E-28 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS17975 e8c6f455bd9dd91148aa35184a0bba37 110 Gene3D G3DSA:3.40.250.10 1 108 6.3E-26 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS17975 e8c6f455bd9dd91148aa35184a0bba37 110 SMART SM00450 7 102 2.8E-19 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS19750 d6ad2072df8d2a98e413466908a584ca 120 Pfam PF02656 Domain of unknown function (DUF202) 12 69 6.3E-10 T 28-03-2018 IPR003807 Domain of unknown function DUF202 WM46_RS19750 d6ad2072df8d2a98e413466908a584ca 120 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 8 71 9.0E-22 T 28-03-2018 IPR020264 Uncharacterised protein family YidG WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 Gene3D G3DSA:3.40.1280.10 186 345 1.8E-36 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 Gene3D G3DSA:3.30.1330.30 97 179 6.7E-9 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 110 181 1.4E-12 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 Pfam PF00588 SpoU rRNA Methylase family 199 336 1.6E-28 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 SUPERFAMILY SSF55315 103 179 7.06E-10 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 PIRSF PIRSF006280 1 345 5.3E-170 T 28-03-2018 IPR016479 tRNA/rRNA methyltransferase, YfiF, predicted GO:0008168 WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 SUPERFAMILY SSF75217 187 343 4.97E-36 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS00340 4e915935cd26e65376cc759d8ca1b396 345 SMART SM00967 109 184 4.0E-9 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Gene3D G3DSA:3.90.600.10 330 425 1.3E-35 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 1.6E-83 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Gene3D G3DSA:3.30.470.20 191 329 1.1E-62 T 28-03-2018 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 43.905 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Gene3D G3DSA:3.40.50.20 2 95 2.2E-37 T 28-03-2018 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 SUPERFAMILY SSF51246 329 424 3.51E-34 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 SUPERFAMILY SSF56059 104 323 9.72E-70 T 28-03-2018 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 SUPERFAMILY SSF52440 1 103 4.03E-37 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 332 422 2.4E-30 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 425 1.9E-189 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 SMART SM01210 330 424 1.6E-57 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Gene3D G3DSA:3.30.1490.20 135 189 5.9E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 SMART SM01209 103 296 1.5E-142 T 28-03-2018 WM46_RS21295 634db1ac5eaf0045d37144d74ee18160 429 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 1.3E-35 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS03185 fe9499a539b5cc4e2262ab82876dea5f 293 Gene3D G3DSA:3.40.50.300 45 278 1.4E-10 T 28-03-2018 WM46_RS03185 fe9499a539b5cc4e2262ab82876dea5f 293 Pfam PF01695 IstB-like ATP binding protein 107 264 4.6E-19 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 WM46_RS03185 fe9499a539b5cc4e2262ab82876dea5f 293 SUPERFAMILY SSF52540 141 269 7.03E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 232 1.2E-19 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 Gene3D G3DSA:3.30.1240.10 83 176 2.4E-25 T 28-03-2018 WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 5.5E-51 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 ProSitePatterns PS01229 Hypothetical cof family signature 2. 213 235 - T 28-03-2018 WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 Gene3D G3DSA:1.20.1110.10 177 264 3.5E-4 T 28-03-2018 WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 Gene3D G3DSA:3.40.50.1000 1 32 0.1 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 1.2E-60 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS10320 bd4ccfcbb551b323ceb2d7220f1e6ec4 271 SUPERFAMILY SSF56784 1 263 1.93E-62 T 28-03-2018 IPR023214 HAD-like domain WM46_RS06045 474013ea598e4d9de7e23043ace90932 268 Gene3D G3DSA:3.40.50.300 2 257 7.1E-66 T 28-03-2018 WM46_RS06045 474013ea598e4d9de7e23043ace90932 268 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS06045 474013ea598e4d9de7e23043ace90932 268 SUPERFAMILY SSF52540 5 251 5.64E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06045 474013ea598e4d9de7e23043ace90932 268 SMART SM00382 39 228 1.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06045 474013ea598e4d9de7e23043ace90932 268 Pfam PF00005 ABC transporter 31 178 1.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Pfam PF05190 MutS family domain IV 428 517 3.6E-28 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Gene3D G3DSA:3.40.1170.10 2 134 9.4E-48 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Gene3D G3DSA:1.10.1420.10 408 535 6.2E-31 T 28-03-2018 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 PIRSF PIRSF037677 4 190 6.9E-28 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 PIRSF PIRSF037677 219 831 2.2E-126 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 SUPERFAMILY SSF55271 5 116 4.05E-43 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 SMART SM00533 286 591 7.4E-109 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Pfam PF01624 MutS domain I 11 122 8.0E-43 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 SMART SM00534 607 794 1.0E-123 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 688 704 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Gene3D G3DSA:3.40.50.300 567 821 2.3E-42 T 28-03-2018 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 850 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 845 25.445 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Pfam PF00488 MutS domain V 610 797 1.6E-88 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 SUPERFAMILY SSF52540 567 798 8.22E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 SUPERFAMILY SSF48334 270 566 4.71E-90 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 SUPERFAMILY SSF53150 117 269 2.62E-43 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Pfam PF05188 MutS domain II 131 256 9.3E-34 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Gene3D G3DSA:3.30.420.110 135 265 9.0E-27 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Pfam PF05192 MutS domain III 272 559 7.6E-40 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 WM46_RS25320 d13f5bb511ce6ab8452269e5fde6bf15 853 Gene3D G3DSA:1.10.1420.10 266 407 1.3E-36 T 28-03-2018 WM46_RS14650 4df02acfbab5c70c9b90751771ca0b47 261 Gene3D G3DSA:3.90.226.10 4 214 5.3E-65 T 28-03-2018 WM46_RS14650 4df02acfbab5c70c9b90751771ca0b47 261 Hamap MF_01051 Carnitinyl-CoA dehydratase [caiD]. 1 261 71.711 T 28-03-2018 IPR022852 Carnitinyl-CoA dehydratase GO:0016836 WM46_RS14650 4df02acfbab5c70c9b90751771ca0b47 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 260 2.5E-83 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 WM46_RS14650 4df02acfbab5c70c9b90751771ca0b47 261 Gene3D G3DSA:1.10.12.10 215 261 2.5E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal WM46_RS14650 4df02acfbab5c70c9b90751771ca0b47 261 SUPERFAMILY SSF52096 2 261 1.46E-77 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS14650 4df02acfbab5c70c9b90751771ca0b47 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 7 89 5.7E-41 T 28-03-2018 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 PIRSF PIRSF001500 1 380 3.2E-142 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 Gene3D G3DSA:3.30.70.260 288 383 4.9E-25 T 28-03-2018 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 SUPERFAMILY SSF48600 6 93 6.96E-23 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 Pfam PF00800 Prephenate dehydratase 106 286 1.6E-58 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 Pfam PF01817 Chorismate mutase type II 11 89 2.0E-17 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 Gene3D G3DSA:3.40.190.10 198 273 4.2E-23 T 28-03-2018 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 325 332 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 Gene3D G3DSA:3.40.190.10 113 197 3.3E-30 T 28-03-2018 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 Gene3D G3DSA:1.20.59.10 1 112 1.8E-30 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 SUPERFAMILY SSF55021 280 377 2.44E-22 T 28-03-2018 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 SMART SM00830 11 91 8.7E-26 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00245 387216f8755786c023f0df66a5e3d1ca 386 SUPERFAMILY SSF53850 105 291 3.91E-53 T 28-03-2018 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 SUPERFAMILY SSF116726 413 483 8.5E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 SUPERFAMILY SSF56176 497 571 3.0E-9 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 SMART SM01091 492 573 4.4E-15 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 Gene3D G3DSA:3.30.465.10 492 573 7.3E-8 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 Pfam PF03471 Transporter associated domain 493 571 1.2E-9 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 Pfam PF00999 Sodium/hydrogen exchanger family 16 388 4.6E-59 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 Pfam PF02080 TrkA-C domain 421 483 1.6E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 Gene3D G3DSA:3.30.70.1450 415 487 2.1E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS05185 9a0513d81ab222d70d4605c1b4a5a152 577 Hamap MF_01075 K(+)/H(+) antiporter NhaP2 [nhaP2]. 1 576 49.69 T 28-03-2018 IPR023729 K(+)/H(+) antiporter NhaP2 GO:0005451|GO:0006812|GO:0006813|GO:0006884|GO:0016021 WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 SUPERFAMILY SSF53092 2 174 2.62E-52 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 Gene3D G3DSA:3.40.350.10 1 171 3.4E-47 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 Gene3D G3DSA:3.90.230.10 172 437 3.2E-89 T 28-03-2018 WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 SUPERFAMILY SSF55920 175 433 2.62E-88 T 28-03-2018 IPR000994 Peptidase M24 WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 SMART SM01011 1 136 1.6E-57 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 126 3.0E-35 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 348 360 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site WM46_RS24185 b250dd56f63de4e818f70071e1c696c2 437 Pfam PF00557 Metallopeptidase family M24 181 411 3.0E-66 T 28-03-2018 IPR000994 Peptidase M24 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 SMART SM01185 69 125 1.1E-14 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 62 9.6E-17 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 TIGRFAM TIGR02178 yeiP: elongation factor P-like protein YeiP 3 189 5.2E-101 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 SMART SM00841 133 188 3.1E-27 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Hamap MF_00646 Elongation factor P-like protein [yeiP]. 2 189 43.661 T 28-03-2018 IPR011897 Translation elongation factor P-like, YeiP WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 SUPERFAMILY SSF50104 1 65 1.93E-11 T 28-03-2018 IPR008991 Translation protein SH3-like domain WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Pfam PF09285 Elongation factor P, C-terminal 133 188 4.5E-19 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Gene3D G3DSA:2.40.50.140 66 131 1.1E-15 T 28-03-2018 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 SUPERFAMILY SSF50249 132 189 7.37E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Gene3D G3DSA:2.30.30.30 2 63 3.6E-16 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 124 4.4E-14 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 PIRSF PIRSF005901 1 190 7.3E-61 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 Gene3D G3DSA:2.40.50.140 133 188 4.4E-21 T 28-03-2018 WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 ProSitePatterns PS01275 Elongation factor P signature. 154 173 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site WM46_RS02355 0a852d4e15e4e919a24fa0c118156575 190 SUPERFAMILY SSF50249 67 130 1.03E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 Pfam PF01966 HD domain 26 138 9.5E-13 T 28-03-2018 IPR006674 HD domain WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 SMART SM00471 227 340 27.0 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 SMART SM00471 20 148 6.7E-4 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 SUPERFAMILY SSF109604 18 179 6.28E-16 T 28-03-2018 WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 Gene3D G3DSA:1.10.3210.10 2 184 3.8E-21 T 28-03-2018 WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 Gene3D G3DSA:1.10.3210.10 210 387 3.4E-6 T 28-03-2018 WM46_RS22140 e8f24c5393c7430dc15d7c20905eb8b6 390 SUPERFAMILY SSF109604 211 329 1.69E-7 T 28-03-2018 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 SUPERFAMILY SSF57802 429 478 3.62E-18 T 28-03-2018 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Gene3D G3DSA:3.60.15.10 1 247 1.8E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 PIRSF PIRSF005243 1 399 1.9E-162 T 28-03-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Gene3D G3DSA:3.40.50.360 253 395 1.2E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Pfam PF00753 Metallo-beta-lactamase superfamily 34 173 2.0E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Pfam PF00258 Flavodoxin 256 388 2.0E-12 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 SUPERFAMILY SSF56281 8 285 2.36E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 SUPERFAMILY SSF52218 251 396 4.51E-34 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Pfam PF00301 Rubredoxin 429 474 1.7E-20 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 PRINTS PR00163 Rubredoxin signature 428 444 1.2E-6 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 PRINTS PR00163 Rubredoxin signature 458 474 1.2E-6 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Hamap MF_01312 Anaerobic nitric oxide reductase flavorubredoxin [norV]. 1 478 94.467 T 28-03-2018 IPR023957 Anaerobic nitric oxide reductase flavorubredoxin GO:0005506|GO:0016966 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 Gene3D G3DSA:2.20.28.10 427 479 1.1E-19 T 28-03-2018 WM46_RS25465 81e8be95ba61dcdb555065f0d5472eb8 482 SMART SM00849 34 210 1.1E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS25680 d6268bb520f19616e088531911be202c 149 Hamap MF_00914 L-alanine exporter AlaE [alaE]. 1 144 34.066 T 28-03-2018 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 WM46_RS25680 d6268bb520f19616e088531911be202c 149 ProDom PD090021 MEMBRANE YGAW TRANSMEMBRANE INNER VV2263 Y3636 VC1828 VP1070 8 141 9.0E-67 T 28-03-2018 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 WM46_RS25680 d6268bb520f19616e088531911be202c 149 Pfam PF06610 L-alanine exporter 4 141 2.2E-67 T 28-03-2018 IPR010574 L-alanine exporter AlaE GO:0016021|GO:0034639 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 SUPERFAMILY SSF50692 1082 1235 7.69E-48 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Gene3D G3DSA:3.40.228.10 225 660 4.2E-105 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Pfam PF00384 Molybdopterin oxidoreductase 108 833 3.5E-189 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Gene3D G3DSA:2.40.40.20 1048 1238 1.0E-47 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Pfam PF01568 Molydopterin dinucleotide binding domain 1088 1202 9.8E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1235 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Gene3D G3DSA:2.20.25.90 55 98 9.1E-29 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Gene3D G3DSA:3.40.50.740 108 214 1.6E-4 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Gene3D G3DSA:4.10.1200.10 1 26 6.6E-15 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 SUPERFAMILY SSF53706 4 1070 0.0 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 SMART SM00926 43 105 9.8E-9 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 777 794 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 1.5E-16 T 28-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 Gene3D G3DSA:3.30.2070.10 795 835 1.5E-5 T 28-03-2018 WM46_RS05635 82dee6a9dc9ed12a92ce3a1ca2d45dcd 1247 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1125 1152 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 SMART SM00851 25 118 1.7E-26 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 PIRSF PIRSF006614 8 151 8.9E-67 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 Gene3D G3DSA:3.40.50.1380 1 152 1.2E-44 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 12 131 40.889 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 11 151 2.5E-73 T 28-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 SUPERFAMILY SSF52335 2 147 8.24E-59 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 Pfam PF02142 MGS-like domain 26 118 2.8E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS09615 1fcbaba18959d9f9dd27fd4c7557c57c 152 ProSitePatterns PS01335 Methylglyoxal synthase active site. 65 73 - T 28-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 199 0.0013 T 28-03-2018 WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 SUPERFAMILY SSF51735 10 244 1.06E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 Gene3D G3DSA:3.40.50.720 1 253 3.2E-61 T 28-03-2018 WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS05875 8d6f65a8d78c378d32e10268e638a193 253 Pfam PF00106 short chain dehydrogenase 14 209 2.1E-53 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01120 8eeb8f2ea59b2a107049d889fb6b79f6 169 Gene3D G3DSA:2.70.70.10 9 169 2.1E-59 T 28-03-2018 WM46_RS01120 8eeb8f2ea59b2a107049d889fb6b79f6 169 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 23 143 3.2E-51 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS01120 8eeb8f2ea59b2a107049d889fb6b79f6 169 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 22 146 1.1E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS01120 8eeb8f2ea59b2a107049d889fb6b79f6 169 SUPERFAMILY SSF51261 12 167 9.77E-57 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS01120 8eeb8f2ea59b2a107049d889fb6b79f6 169 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 85 97 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS22935 b98653858e7f9fdaac580167d3c35a22 333 SUPERFAMILY SSF53850 24 246 3.06E-39 T 28-03-2018 WM46_RS22935 b98653858e7f9fdaac580167d3c35a22 333 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 230 5.1E-17 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 WM46_RS22935 b98653858e7f9fdaac580167d3c35a22 333 SMART SM00062 26 241 5.6E-5 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS22935 b98653858e7f9fdaac580167d3c35a22 333 Gene3D G3DSA:3.40.190.10 120 331 1.1E-32 T 28-03-2018 WM46_RS22935 b98653858e7f9fdaac580167d3c35a22 333 Gene3D G3DSA:3.40.190.10 21 116 3.0E-12 T 28-03-2018 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 Pfam PF01467 Cytidylyltransferase-like 6 134 1.4E-22 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 Gene3D G3DSA:3.40.50.620 1 159 4.3E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.848 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 1.1E-61 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 0.004 T 28-03-2018 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 3.7E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 3.7E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 3.7E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 3.7E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 3.7E-51 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 SUPERFAMILY SSF52374 3 156 4.56E-46 T 28-03-2018 WM46_RS20160 dad75b1aeb8d5555cefcb5de966227ac 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 61 1.6E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 7 113 3.6E-33 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 Gene3D G3DSA:3.40.50.720 263 359 7.6E-10 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 SUPERFAMILY SSF51971 126 347 2.18E-46 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 126 395 6.6E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 Gene3D G3DSA:3.50.50.60 360 410 1.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 Gene3D G3DSA:3.50.50.60 125 262 1.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 361 383 8.8E-18 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 274 8.8E-18 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 146 8.8E-18 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 338 354 8.8E-18 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 Gene3D G3DSA:1.10.1060.10 1 124 1.3E-31 T 28-03-2018 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 371 389 6.1E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 252 276 6.1E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 148 6.1E-11 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS01440 6f3f0e00577865a098b47086797d40ac 410 SUPERFAMILY SSF46548 8 135 2.04E-26 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 SUPERFAMILY SSF46785 3 86 4.82E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 Gene3D G3DSA:1.10.10.10 4 91 5.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 Gene3D G3DSA:3.40.190.10 94 177 2.2E-13 T 28-03-2018 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 Pfam PF03466 LysR substrate binding domain 91 292 8.8E-42 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 Gene3D G3DSA:3.40.190.10 178 263 3.5E-23 T 28-03-2018 WM46_RS24975 8007bd0a2471cdb16bbb3e0c7fca2192 305 SUPERFAMILY SSF53850 93 295 1.71E-41 T 28-03-2018 WM46_RS16290 d481e7381e3143c9539563375d5ed7c9 205 Gene3D G3DSA:3.40.50.300 8 176 8.3E-18 T 28-03-2018 WM46_RS16290 d481e7381e3143c9539563375d5ed7c9 205 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 178 3.3E-40 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain WM46_RS16290 d481e7381e3143c9539563375d5ed7c9 205 SUPERFAMILY SSF52540 4 199 8.52E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16290 d481e7381e3143c9539563375d5ed7c9 205 Hamap MF_01389 Urease accessory protein UreG [ureG]. 6 204 47.184 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 WM46_RS16290 d481e7381e3143c9539563375d5ed7c9 205 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 8 202 7.0E-101 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 WM46_RS16290 d481e7381e3143c9539563375d5ed7c9 205 PIRSF PIRSF005624 2 204 6.9E-50 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 SUPERFAMILY SSF55729 1 337 3.03E-134 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 3 337 3.6E-152 T 28-03-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 3 337 1.7E-163 T 28-03-2018 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 Hamap MF_01171 Arginine N-succinyltransferase [astA]. 1 343 71.785 T 28-03-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 Gene3D G3DSA:2.40.40.20 274 337 4.2E-20 T 28-03-2018 WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 Gene3D G3DSA:3.40.630.30 1 273 6.2E-27 T 28-03-2018 WM46_RS08190 77065abb2789662da0d9951373f16fd6 344 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 335 2.0E-145 T 28-03-2018 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109 WM46_RS01395 09990087e759b601c50b6b8267c0512d 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 246 1.2E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS01395 09990087e759b601c50b6b8267c0512d 255 Gene3D G3DSA:3.40.190.10 13 147 9.6E-36 T 28-03-2018 WM46_RS01395 09990087e759b601c50b6b8267c0512d 255 SMART SM00062 25 248 1.1E-59 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS01395 09990087e759b601c50b6b8267c0512d 255 SUPERFAMILY SSF53850 8 248 8.26E-66 T 28-03-2018 WM46_RS01395 09990087e759b601c50b6b8267c0512d 255 SMART SM00079 25 247 1.7E-6 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 WM46_RS01395 09990087e759b601c50b6b8267c0512d 255 Gene3D G3DSA:3.40.190.10 148 252 1.3E-14 T 28-03-2018 WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 SUPERFAMILY SSF50331 238 329 1.98E-9 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 Gene3D G3DSA:2.40.50.140 259 325 3.7E-6 T 28-03-2018 WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 Pfam PF00005 ABC transporter 21 162 6.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 Pfam PF08402 TOBE domain 257 331 1.9E-15 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 SMART SM00382 29 212 1.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 SUPERFAMILY SSF52540 5 242 8.49E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS06560 001d4043c3bfc43ef1fd539b458cd590 337 Gene3D G3DSA:3.40.50.300 1 240 3.0E-71 T 28-03-2018 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 SUPERFAMILY SSF55031 181 294 6.43E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 Gene3D G3DSA:3.40.630.10 1 183 1.6E-28 T 28-03-2018 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 SUPERFAMILY SSF53187 305 381 7.43E-58 T 28-03-2018 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 SUPERFAMILY SSF53187 3 180 7.43E-58 T 28-03-2018 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 Pfam PF01546 Peptidase family M20/M25/M40 76 377 5.7E-32 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 110 147 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 Gene3D G3DSA:3.30.70.360 184 299 4.5E-21 T 28-03-2018 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 10 377 6.9E-165 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 Hamap MF_01108 Acetylornithine deacetylase [argE]. 3 382 66.784 T 28-03-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 WM46_RS20990 a07c50e6b50588caab1d50d160b220f9 383 Pfam PF07687 Peptidase dimerisation domain 178 288 5.1E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 380 2.3E-142 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 190 204 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 PIRSF PIRSF001434 1 384 3.9E-133 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 3 382 5.9E-212 T 28-03-2018 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|MetaCyc: PWY-801 WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 Gene3D G3DSA:3.40.640.10 1 247 2.3E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 SUPERFAMILY SSF53383 5 381 1.27E-119 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS20890 4f381689b61582f06e8cfb316651fa22 386 Gene3D G3DSA:3.90.1150.10 248 386 4.0E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 2.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 Gene3D G3DSA:3.40.190.10 98 185 3.4E-12 T 28-03-2018 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 Gene3D G3DSA:1.10.10.10 8 89 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 Pfam PF03466 LysR substrate binding domain 99 296 1.6E-31 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 Gene3D G3DSA:3.40.190.10 186 270 1.2E-9 T 28-03-2018 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 SUPERFAMILY SSF53850 99 298 1.14E-29 T 28-03-2018 WM46_RS16505 c82f8899cbceac2553ec4f53e66846ca 312 SUPERFAMILY SSF46785 7 115 8.88E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02715 d9c59f9251fac4a4d986217a299d5181 453 Pfam PF16325 Peptidase family U32 C-terminal domain 359 439 2.7E-21 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal WM46_RS02715 d9c59f9251fac4a4d986217a299d5181 453 Pfam PF01136 Peptidase family U32 75 343 5.7E-97 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS02715 d9c59f9251fac4a4d986217a299d5181 453 Gene3D G3DSA:3.20.20.70 8 170 1.3E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS02715 d9c59f9251fac4a4d986217a299d5181 453 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 260 9.4E-60 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 Gene3D G3DSA:3.40.50.1000 2 266 4.1E-36 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 ProSitePatterns PS01229 Hypothetical cof family signature 2. 212 234 - T 28-03-2018 WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 260 5.9E-67 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 231 1.0E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 SUPERFAMILY SSF56784 1 265 1.0E-66 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19050 55d445a99458b00d0b3c05325516238d 266 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 PIRSF PIRSF001356 1 263 3.4E-155 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 Gene3D G3DSA:3.60.90.10 32 189 1.3E-45 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 264 174.668 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 Pfam PF02675 S-adenosylmethionine decarboxylase 33 169 2.3E-30 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 3 261 5.0E-148 T 28-03-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 SUPERFAMILY SSF56276 112 173 5.1E-23 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 WM46_RS14185 90bcf620d7b6773606fb4f35d6211bac 264 SUPERFAMILY SSF56276 41 84 5.1E-23 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 SMART SM00283 119 366 4.2E-82 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 179 332 1.1E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 SUPERFAMILY SSF58104 86 367 1.1E-67 T 28-03-2018 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 SMART SM00304 66 118 0.0049 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 2.5E-6 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 308 337 2.5E-6 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 Gene3D G3DSA:1.10.287.950 63 173 4.3E-15 T 28-03-2018 WM46_RS23165 f2f1ac97b12450f3657fb07479481998 370 Gene3D G3DSA:1.10.287.950 174 370 6.2E-49 T 28-03-2018 WM46_RS25245 655cf102a67fc4eecdba62d91d764498 201 SUPERFAMILY SSF52540 20 194 1.93E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25245 655cf102a67fc4eecdba62d91d764498 201 Gene3D G3DSA:3.40.50.300 23 201 1.1E-48 T 28-03-2018 WM46_RS25245 655cf102a67fc4eecdba62d91d764498 201 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 10 193 1.0E-89 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 WM46_RS25245 655cf102a67fc4eecdba62d91d764498 201 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 26 197 39.201 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 WM46_RS25245 655cf102a67fc4eecdba62d91d764498 201 Pfam PF01583 Adenylylsulphate kinase 27 179 7.7E-74 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Gene3D G3DSA:3.30.70.1430 40 142 2.2E-25 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82866 811 1010 3.4E-43 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Gene3D G3DSA:3.30.2090.10 701 788 4.2E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Pfam PF00873 AcrB/AcrD/AcrF family 4 1008 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Gene3D G3DSA:1.20.1640.10 801 1022 3.9E-36 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Gene3D G3DSA:1.20.1640.10 281 503 3.7E-49 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Gene3D G3DSA:3.30.2090.10 181 269 8.0E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82693 136 182 1.12E-22 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82693 268 324 1.12E-22 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82693 40 135 5.58E-23 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82693 788 833 1.2E-5 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82693 662 701 1.2E-5 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82866 291 490 2.49E-49 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Hamap MF_01424 Multidrug resistance protein MdtC [mdtC]. 1 1024 27.05 T 28-03-2018 IPR023931 Multidrug resistance protein MdtC WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 605 619 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 9.9E-88 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82693 555 650 1.36E-17 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 Gene3D G3DSA:3.30.70.1430 557 652 1.3E-13 T 28-03-2018 WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82714 703 785 1.57E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02735 823d13c8a9391a2c88923d179a955060 1026 SUPERFAMILY SSF82714 183 266 2.49E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 SUPERFAMILY SSF52540 10 277 1.98E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 3 529 0.0 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 SUPERFAMILY SSF54980 393 468 3.45E-17 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Gene3D G3DSA:3.30.70.870 394 469 9.2E-11 T 28-03-2018 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 527 52.503 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Gene3D G3DSA:2.40.30.10 281 387 3.6E-21 T 28-03-2018 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 387 514 7.4E-47 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Gene3D G3DSA:3.40.50.300 8 280 2.1E-36 T 28-03-2018 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.6E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 PRINTS PR00315 GTP-binding elongation factor signature 15 28 6.6E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.6E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.6E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 PRINTS PR00315 GTP-binding elongation factor signature 65 73 6.6E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Pfam PF00009 Elongation factor Tu GTP binding domain 13 277 2.6E-46 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 Pfam PF03144 Elongation factor Tu domain 2 314 380 3.4E-10 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 156 1.4E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS24060 dcc3d9ae966c7b335c01dbc61b322740 529 SUPERFAMILY SSF50447 262 393 8.95E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 SUPERFAMILY SSF50331 240 344 3.64E-15 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 SMART SM00382 31 214 5.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 Pfam PF08402 TOBE domain 273 344 4.6E-11 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 Pfam PF00005 ABC transporter 23 164 4.9E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 Gene3D G3DSA:2.40.50.140 286 337 2.6E-7 T 28-03-2018 WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 Gene3D G3DSA:3.40.50.300 2 241 8.4E-78 T 28-03-2018 WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 Gene3D G3DSA:2.40.50.100 242 285 0.0017 T 28-03-2018 WM46_RS13120 5a8fb8105e992b345826a1c9103e41d1 348 SUPERFAMILY SSF52540 7 246 4.21E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17820 955fedf4e92ef257b2c2d782ae2b18b5 186 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS17820 955fedf4e92ef257b2c2d782ae2b18b5 186 Pfam PF00293 NUDIX domain 47 150 9.3E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS17820 955fedf4e92ef257b2c2d782ae2b18b5 186 Gene3D G3DSA:3.90.79.10 8 186 2.6E-34 T 28-03-2018 WM46_RS17820 955fedf4e92ef257b2c2d782ae2b18b5 186 SUPERFAMILY SSF55811 3 182 5.01E-39 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS17300 991dac1d6e472f8b24be72019ccfeac6 252 Gene3D G3DSA:3.40.50.300 9 251 2.5E-73 T 28-03-2018 WM46_RS17300 991dac1d6e472f8b24be72019ccfeac6 252 PIRSF PIRSF039085 9 252 7.7E-107 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS17300 991dac1d6e472f8b24be72019ccfeac6 252 SMART SM00382 37 224 5.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS17300 991dac1d6e472f8b24be72019ccfeac6 252 SUPERFAMILY SSF52540 12 246 6.29E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17300 991dac1d6e472f8b24be72019ccfeac6 252 Pfam PF00005 ABC transporter 28 176 3.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS17300 991dac1d6e472f8b24be72019ccfeac6 252 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 Gene3D G3DSA:2.60.40.1180 666 771 2.4E-32 T 28-03-2018 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 Gene3D G3DSA:2.60.40.1180 606 665 2.7E-20 T 28-03-2018 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 SUPERFAMILY SSF74650 1 247 2.64E-66 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 SUPERFAMILY SSF51011 586 665 4.53E-21 T 28-03-2018 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 SUPERFAMILY SSF51445 263 603 1.52E-90 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 Pfam PF01055 Glycosyl hydrolases family 31 240 667 5.4E-122 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 Gene3D G3DSA:2.60.40.1760 1 238 1.2E-55 T 28-03-2018 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 Pfam PF13802 Galactose mutarotase-like 159 218 1.9E-15 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 Gene3D G3DSA:3.20.20.80 239 605 2.8E-112 T 28-03-2018 WM46_RS20030 fffbb53b5ff520cfcbe290e99d5ad445 772 SUPERFAMILY SSF117125 666 770 2.75E-33 T 28-03-2018 WM46_RS00840 e925d43f3d5ac3d38448cff8deea0868 156 Gene3D G3DSA:3.40.30.10 1 154 2.1E-42 T 28-03-2018 WM46_RS00840 e925d43f3d5ac3d38448cff8deea0868 156 PIRSF PIRSF000239 1 153 1.5E-17 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS00840 e925d43f3d5ac3d38448cff8deea0868 156 Pfam PF00578 AhpC/TSA family 7 134 4.5E-39 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS00840 e925d43f3d5ac3d38448cff8deea0868 156 SUPERFAMILY SSF52833 3 154 4.02E-50 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 Gene3D G3DSA:2.60.40.10 155 241 5.3E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 PRINTS PR00969 Pili chaperone signature 109 126 1.9E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 PRINTS PR00969 Pili chaperone signature 31 40 1.9E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 PRINTS PR00969 Pili chaperone signature 80 101 1.9E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 PRINTS PR00969 Pili chaperone signature 135 150 1.9E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 PRINTS PR00969 Pili chaperone signature 170 185 1.9E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 SUPERFAMILY SSF49354 25 153 2.88E-41 T 28-03-2018 IPR008962 PapD-like WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 Gene3D G3DSA:2.60.40.10 31 151 2.1E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 SUPERFAMILY SSF49584 155 240 5.63E-19 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 108 125 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 30 153 8.8E-44 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS05990 6ca3b91ada24eb6b249a196a8a7199c6 244 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 175 238 2.3E-12 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS05795 63cd9bf509adfce3a596c3ec2aba15de 132 Pfam PF03061 Thioesterase superfamily 26 97 1.1E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM46_RS05795 63cd9bf509adfce3a596c3ec2aba15de 132 SUPERFAMILY SSF54637 8 131 2.29E-38 T 28-03-2018 IPR029069 HotDog domain WM46_RS05795 63cd9bf509adfce3a596c3ec2aba15de 132 Gene3D G3DSA:3.10.129.10 1 132 6.6E-34 T 28-03-2018 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 177 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Gene3D G3DSA:1.10.10.60 78 137 2.9E-17 T 28-03-2018 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 SMART SM00342 99 181 1.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 86 128 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 319 325 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 189 266 2.1E-16 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 SUPERFAMILY SSF46689 86 133 7.62E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Gene3D G3DSA:3.40.10.10 1 77 1.0E-26 T 28-03-2018 IPR035451 Ada-like domain WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 PIRSF PIRSF000409 1 354 2.9E-139 T 28-03-2018 IPR016221 Bifunctional regulatory protein Ada WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 270 348 1.5E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Pfam PF12833 Helix-turn-helix domain 105 182 1.2E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 269 348 1.1E-36 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 SUPERFAMILY SSF57884 4 91 1.18E-32 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Pfam PF02805 Metal binding domain of Ada 11 75 1.4E-30 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Gene3D G3DSA:1.10.10.10 265 350 1.0E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 SUPERFAMILY SSF46767 268 349 3.14E-31 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Gene3D G3DSA:3.30.160.70 183 264 5.6E-20 T 28-03-2018 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 Gene3D G3DSA:1.10.10.60 138 182 0.029 T 28-03-2018 WM46_RS02095 393c5eb833e47d8b1da96c30b3258582 354 SUPERFAMILY SSF53155 187 266 1.41E-21 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 Gene3D G3DSA:1.10.10.10 1 85 6.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 Gene3D G3DSA:3.40.190.10 179 270 2.2E-20 T 28-03-2018 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 SUPERFAMILY SSF53850 90 297 1.71E-38 T 28-03-2018 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 Pfam PF03466 LysR substrate binding domain 89 296 2.0E-41 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 SUPERFAMILY SSF46785 4 89 1.41E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 Gene3D G3DSA:3.40.190.10 90 178 1.4E-19 T 28-03-2018 WM46_RS07270 7c1a8bd889b94b145a2c3bf7560758fd 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.7E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 Gene3D G3DSA:3.30.413.10 108 318 4.8E-30 T 28-03-2018 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 TIGRFAM TIGR02912 sulfite_red_C: sulfite reductase, subunit C 4 321 2.4E-160 T 28-03-2018 IPR014261 Sulphite reductase, subunit C WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 SUPERFAMILY SSF56014 110 172 2.13E-28 T 28-03-2018 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 SUPERFAMILY SSF56014 234 325 2.13E-28 T 28-03-2018 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 PRINTS PR00397 Sirohaem Fe-binding site signature 110 128 7.6E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 PRINTS PR00397 Sirohaem Fe-binding site signature 151 169 7.6E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 SUPERFAMILY SSF54862 153 233 8.98E-17 T 28-03-2018 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 151 167 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 212 223 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 110 305 5.1E-16 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 23 82 6.1E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 Pfam PF13187 4Fe-4S dicluster domain 179 224 9.9E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 SUPERFAMILY SSF55124 18 83 4.91E-17 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS00590 e203d33579ac5f3bfac9b3bcd6277b17 337 Gene3D G3DSA:3.90.480.10 13 84 2.6E-10 T 28-03-2018 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 Gene3D G3DSA:3.40.640.10 140 444 5.6E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 Gene3D G3DSA:3.90.1150.10 447 639 5.7E-55 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 SUPERFAMILY SSF55904 610 754 1.57E-37 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 SUPERFAMILY SSF53383 140 607 1.08E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 140 590 2.0E-191 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 18 134 9.8E-26 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 615 743 3.7E-44 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 Gene3D G3DSA:3.90.100.10 640 755 2.4E-29 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 PIRSF PIRSF009393 1 755 2.6E-273 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 WM46_RS21960 f17a612aee3f36be1ef2e1e4760523a6 755 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 381 395 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 SUPERFAMILY SSF51556 51 346 2.72E-96 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 Gene3D G3DSA:2.30.40.10 1 64 1.1E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 Gene3D G3DSA:3.20.20.140 65 346 1.5E-100 T 28-03-2018 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 4 372 2.6E-85 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 SUPERFAMILY SSF51338 346 374 2.46E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 SUPERFAMILY SSF51338 2 49 2.46E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 Pfam PF01979 Amidohydrolase family 47 364 7.3E-20 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS16615 b7d180f402be6eddb24869c5382870b4 377 PIRSF PIRSF038994 1 375 1.6E-114 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 WM46_RS09280 cd7d91957e3d8c2ca4fa510994f536bf 215 Pfam PF01081 KDPG and KHG aldolase 9 200 2.0E-45 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS09280 cd7d91957e3d8c2ca4fa510994f536bf 215 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS09280 cd7d91957e3d8c2ca4fa510994f536bf 215 SUPERFAMILY SSF51569 2 208 1.25E-61 T 28-03-2018 WM46_RS09280 cd7d91957e3d8c2ca4fa510994f536bf 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 206 2.1E-55 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS09280 cd7d91957e3d8c2ca4fa510994f536bf 215 Gene3D G3DSA:3.20.20.70 4 214 2.6E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 SUPERFAMILY SSF53067 242 482 2.92E-64 T 28-03-2018 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 249 435 3.1E-32 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 SUPERFAMILY SSF53067 2 242 1.94E-72 T 28-03-2018 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 PIRSF PIRSF000538 1 484 9.4E-134 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 Gene3D G3DSA:3.30.420.40 238 481 2.5E-59 T 28-03-2018 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 347 367 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 240 6.0E-83 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 Gene3D G3DSA:3.30.420.40 1 237 1.6E-77 T 28-03-2018 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 126 138 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS20460 32950048e83afe034b759459d1f58ee2 484 TIGRFAM TIGR01312 XylB: xylulokinase 3 477 3.3E-190 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 Gene3D G3DSA:1.20.1050.10 97 214 4.1E-27 T 28-03-2018 WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 SUPERFAMILY SSF52833 1 88 4.1E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 1.9E-16 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 Pfam PF14497 Glutathione S-transferase, C-terminal domain 118 199 1.0E-8 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 Gene3D G3DSA:3.40.30.10 1 96 1.1E-24 T 28-03-2018 WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 SUPERFAMILY SSF47616 81 211 1.24E-31 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS02520 f5a79310dd93e5383d632997be4b630d 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 211 1.1E-89 T 28-03-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 241 261 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 Gene3D G3DSA:1.20.1090.10 160 363 5.7E-40 T 28-03-2018 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 150 178 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 SUPERFAMILY SSF56796 3 356 4.71E-82 T 28-03-2018 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 PIRSF PIRSF000112 1 361 2.7E-91 T 28-03-2018 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 Gene3D G3DSA:3.40.50.1970 1 159 5.5E-28 T 28-03-2018 WM46_RS17985 476911c3a2237c9c99ab7779c1302b52 369 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 347 9.5E-65 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 SUPERFAMILY SSF55103 259 542 1.14E-53 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Gene3D G3DSA:3.30.43.10 4 104 5.8E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Gene3D G3DSA:1.10.1060.10 546 703 1.3E-12 T 28-03-2018 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 SUPERFAMILY SSF56176 18 282 5.14E-54 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Pfam PF01565 FAD binding domain 52 192 2.2E-36 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Gene3D G3DSA:1.10.45.10 500 539 2.1E-9 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Gene3D G3DSA:3.30.465.10 105 304 1.2E-43 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 SUPERFAMILY SSF46548 655 691 8.89E-8 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 SUPERFAMILY SSF46548 518 622 8.89E-8 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 673 684 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Pfam PF02913 FAD linked oxidases, C-terminal domain 281 539 5.9E-64 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 WM46_RS07875 5fa018c64ce632e1044591b45bacbc49 1018 Pfam PF13183 4Fe-4S dicluster domain 576 687 4.5E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS04040 900353853e777fdc483b2de94ee47e88 212 Gene3D G3DSA:3.40.1400.10 1 212 1.2E-55 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 WM46_RS04040 900353853e777fdc483b2de94ee47e88 212 Pfam PF02502 Ribose/Galactose Isomerase 3 144 1.7E-28 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 WM46_RS04040 900353853e777fdc483b2de94ee47e88 212 Pfam PF12408 Ribose-5-phosphate isomerase 164 210 2.6E-21 T 28-03-2018 IPR022133 Ribose-5-phosphate isomerase, C-terminal WM46_RS04040 900353853e777fdc483b2de94ee47e88 212 SUPERFAMILY SSF89623 1 161 3.01E-36 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 Pfam PF03441 FAD binding domain of DNA photolyase 273 467 1.4E-85 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 Pfam PF00875 DNA photolyase 5 173 2.8E-47 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 343 362 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 Gene3D G3DSA:3.40.50.620 1 127 8.2E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 Gene3D G3DSA:1.25.40.80 132 290 5.9E-40 T 28-03-2018 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 Gene3D G3DSA:1.10.579.10 293 471 4.9E-76 T 28-03-2018 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 SUPERFAMILY SSF48173 194 471 3.66E-109 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 323 335 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 PRINTS PR00147 DNA photolyase signature 323 339 1.8E-32 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 PRINTS PR00147 DNA photolyase signature 382 396 1.8E-32 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 PRINTS PR00147 DNA photolyase signature 343 361 1.8E-32 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 PRINTS PR00147 DNA photolyase signature 143 159 1.8E-32 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 WM46_RS11075 5d5b31b05099f1cb0479363c23c46e5d 472 SUPERFAMILY SSF52425 3 198 4.97E-56 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 WM46_RS20175 b8f4ed1adc3aec3dc61b324bf1d16c17 374 Pfam PF00534 Glycosyl transferases group 1 184 350 1.3E-37 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS20175 b8f4ed1adc3aec3dc61b324bf1d16c17 374 Gene3D G3DSA:3.40.50.2000 183 355 3.2E-38 T 28-03-2018 WM46_RS20175 b8f4ed1adc3aec3dc61b324bf1d16c17 374 SUPERFAMILY SSF53756 3 354 1.61E-64 T 28-03-2018 WM46_RS20175 b8f4ed1adc3aec3dc61b324bf1d16c17 374 Gene3D G3DSA:3.40.50.2000 2 182 1.8E-5 T 28-03-2018 WM46_RS20175 b8f4ed1adc3aec3dc61b324bf1d16c17 374 Pfam PF13439 Glycosyltransferase Family 4 13 173 7.5E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 WM46_RS23430 7f0dbbf83946119b1d91cc373bcd2bf9 360 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 358 5.5E-73 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM46_RS23430 7f0dbbf83946119b1d91cc373bcd2bf9 360 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 6 358 2.9E-137 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 WM46_RS10400 11bc662f31b1bc8e222afef7a0f4b58b 295 SUPERFAMILY SSF103481 185 278 1.31E-10 T 28-03-2018 WM46_RS10400 11bc662f31b1bc8e222afef7a0f4b58b 295 SUPERFAMILY SSF103481 46 136 1.31E-6 T 28-03-2018 WM46_RS10400 11bc662f31b1bc8e222afef7a0f4b58b 295 Pfam PF00892 EamA-like transporter family 148 277 4.1E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 SUPERFAMILY SSF53067 4 195 3.24E-67 T 28-03-2018 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PRINTS PR00471 Acetate kinase family signature 173 186 1.4E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PRINTS PR00471 Acetate kinase family signature 5 16 1.4E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PRINTS PR00471 Acetate kinase family signature 374 386 1.4E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PRINTS PR00471 Acetate kinase family signature 203 224 1.4E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PRINTS PR00471 Acetate kinase family signature 300 313 1.4E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PRINTS PR00471 Acetate kinase family signature 322 338 1.4E-42 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 Gene3D G3DSA:3.30.420.40 197 403 1.2E-77 T 28-03-2018 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 SUPERFAMILY SSF53067 157 392 2.39E-86 T 28-03-2018 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 Hamap MF_00020 Acetate kinase [ackA]. 1 396 180.765 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 Hamap MF_01882 Probable propionate kinase [pduW]. 1 392 72.695 T 28-03-2018 IPR024896 Propionate kinase PduW GO:0008980|GO:0019543|GO:0051144 KEGG: 00640+2.7.2.15|MetaCyc: PWY-5437|MetaCyc: PWY-7013 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 TIGRFAM TIGR00016 ackA: acetate kinase 2 392 2.0E-153 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 Gene3D G3DSA:3.30.420.40 4 195 7.7E-74 T 28-03-2018 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 PIRSF PIRSF000722 1 397 3.7E-148 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS03430 63d67ff5ac3ca03a6e74cfd1a0ab84fd 404 Pfam PF00871 Acetokinase family 4 387 8.8E-148 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS02340 1d28d44ae6a738dac107cf317cdfc78c 377 Gene3D G3DSA:1.10.1130.10 104 376 8.5E-22 T 28-03-2018 WM46_RS02340 1d28d44ae6a738dac107cf317cdfc78c 377 PIRSF PIRSF000014 1 376 3.0E-131 T 28-03-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 WM46_RS02340 1d28d44ae6a738dac107cf317cdfc78c 377 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 5 175 3.8E-58 T 28-03-2018 IPR005126 NapC/NirT cytochrome c, N-terminal WM46_RS02340 1d28d44ae6a738dac107cf317cdfc78c 377 Gene3D G3DSA:1.10.1130.10 18 103 3.2E-6 T 28-03-2018 WM46_RS02340 1d28d44ae6a738dac107cf317cdfc78c 377 SUPERFAMILY SSF48695 9 176 9.75E-43 T 28-03-2018 IPR011031 Multihaem cytochrome WM46_RS04210 7927311f6b91b2c415005b0f96023e77 192 Gene3D G3DSA:2.60.40.1090 29 192 9.7E-27 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS04210 7927311f6b91b2c415005b0f96023e77 192 SUPERFAMILY SSF49401 30 191 2.09E-22 T 28-03-2018 IPR008966 Adhesion domain WM46_RS04210 7927311f6b91b2c415005b0f96023e77 192 Pfam PF00419 Fimbrial protein 31 191 4.7E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 Gene3D G3DSA:3.30.70.20 1 18 0.018 T 28-03-2018 WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 Gene3D G3DSA:3.30.70.20 19 70 5.4E-11 T 28-03-2018 WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 SUPERFAMILY SSF54862 1 170 1.5E-43 T 28-03-2018 WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 Pfam PF12798 4Fe-4S binding domain 131 151 0.017 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 Gene3D G3DSA:3.30.70.20 126 179 3.6E-9 T 28-03-2018 WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 Gene3D G3DSA:3.30.70.20 71 125 9.8E-18 T 28-03-2018 WM46_RS25450 60b33d1b5bff1e7ad4534893a6b06996 181 Pfam PF13247 4Fe-4S dicluster domain 55 104 4.2E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 4.9E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00183 E.coli/Salmonella-type porin signature 151 173 4.9E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00183 E.coli/Salmonella-type porin signature 96 118 4.9E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00183 E.coli/Salmonella-type porin signature 237 254 4.9E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00183 E.coli/Salmonella-type porin signature 266 285 4.9E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 4.9E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 Gene3D G3DSA:2.40.160.10 32 358 4.0E-56 T 28-03-2018 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 5.1E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 96 106 5.1E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 310 327 5.1E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 153 164 5.1E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 231 243 5.1E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 310 326 - T 28-03-2018 IPR013793 Porin, Gram-negative type, conserved site WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 Pfam PF00267 Gram-negative porin 27 358 1.1E-153 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06770 752a122df20c7c9c49ad41e3b889c044 358 SUPERFAMILY SSF56935 22 358 1.36E-85 T 28-03-2018 WM46_RS02200 2ffe0fc3e0d943dbeba1c2e3ce073abc 350 Gene3D G3DSA:1.25.40.10 210 350 3.2E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS02200 2ffe0fc3e0d943dbeba1c2e3ce073abc 350 SUPERFAMILY SSF48452 221 328 6.33E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS02200 2ffe0fc3e0d943dbeba1c2e3ce073abc 350 Pfam PF14559 Tetratricopeptide repeat 237 296 5.7E-7 T 28-03-2018 WM46_RS02200 2ffe0fc3e0d943dbeba1c2e3ce073abc 350 Pfam PF03918 Cytochrome C biogenesis protein 7 132 8.5E-51 T 28-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family WM46_RS24285 824d96750827698af05272d241978410 182 Gene3D G3DSA:3.90.79.10 31 181 1.2E-28 T 28-03-2018 WM46_RS24285 824d96750827698af05272d241978410 182 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 4 177 33.402 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 WM46_RS24285 824d96750827698af05272d241978410 182 PIRSF PIRSF018427 1 181 1.4E-57 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 WM46_RS24285 824d96750827698af05272d241978410 182 Pfam PF00293 NUDIX domain 31 161 4.7E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS24285 824d96750827698af05272d241978410 182 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 6 165 6.7E-48 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 WM46_RS24285 824d96750827698af05272d241978410 182 SUPERFAMILY SSF55811 4 166 7.31E-50 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS15845 8abce50eb91128b8a1effd55575cf81b 83 SUPERFAMILY SSF54786 12 75 1.69E-24 T 28-03-2018 WM46_RS15845 8abce50eb91128b8a1effd55575cf81b 83 Pfam PF06006 Bacterial protein of unknown function (DUF905) 8 74 5.1E-29 T 28-03-2018 IPR009253 Protein of unknown function DUF905 WM46_RS15845 8abce50eb91128b8a1effd55575cf81b 83 Gene3D G3DSA:3.30.160.130 7 76 2.3E-34 T 28-03-2018 WM46_RS15845 8abce50eb91128b8a1effd55575cf81b 83 ProDom PD028015 PLASMID YKFF YDEA R0111 YPJI YPMT1.60C C4569 AEC70 PSLT067 YFJA 9 74 1.0E-20 T 28-03-2018 IPR009253 Protein of unknown function DUF905 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 SUPERFAMILY SSF53738 305 446 3.06E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 482 538 3.9E-8 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 SUPERFAMILY SSF53738 209 317 2.82E-8 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 SUPERFAMILY SSF53738 26 235 9.89E-50 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 544 0.0 T 28-03-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Gene3D G3DSA:3.40.120.10 12 212 4.3E-47 T 28-03-2018 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 320 440 1.2E-30 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 SUPERFAMILY SSF55957 433 544 1.1E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 179 2.9E-36 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Gene3D G3DSA:3.40.120.10 326 442 2.1E-27 T 28-03-2018 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Gene3D G3DSA:3.30.310.50 443 546 3.2E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 1.9E-20 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS11145 325652785a4657ca6779815ed84ef623 546 Gene3D G3DSA:3.40.120.10 213 325 4.2E-21 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 372 604 2.3E-48 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 72 337 2.0E-37 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF81660 316 450 6.21E-37 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF81653 117 207 5.23E-21 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF81665 619 662 3.53E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF81665 30 103 3.53E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF81665 208 299 3.53E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 680 41.593 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 Gene3D G3DSA:3.40.1110.10 316 443 4.3E-24 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF56784 293 317 5.95E-39 T 28-03-2018 IPR023214 HAD-like domain WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF56784 377 404 5.95E-39 T 28-03-2018 IPR023214 HAD-like domain WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 SUPERFAMILY SSF56784 435 559 5.95E-39 T 28-03-2018 IPR023214 HAD-like domain WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 Pfam PF00122 E1-E2 ATPase 117 282 5.8E-34 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 Gene3D G3DSA:3.40.50.1000 444 577 3.5E-34 T 28-03-2018 IPR023214 HAD-like domain WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 307 313 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 2 677 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 Pfam PF00702 haloacid dehalogenase-like hydrolase 301 530 2.4E-37 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 154 168 3.7E-24 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 551 3.7E-24 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 473 3.7E-24 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 305 319 3.7E-24 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 516 535 3.7E-24 T 28-03-2018 WM46_RS11100 bf36f3e5cde2061a1a425fefe8d29a03 682 Gene3D G3DSA:2.70.150.10 17 208 1.5E-23 T 28-03-2018 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 Gene3D G3DSA:3.40.720.10 147 320 1.2E-32 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 Gene3D G3DSA:3.30.1120.10 323 470 7.8E-16 T 28-03-2018 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 SUPERFAMILY SSF53649 30 363 3.68E-79 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 SUPERFAMILY SSF53649 419 464 3.68E-79 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 Gene3D G3DSA:3.40.720.10 28 146 2.0E-21 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 Pfam PF00884 Sulfatase 152 298 1.8E-20 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS20915 e94be49aedbb2bb2bcd2abeeea22dd7e 491 Pfam PF00884 Sulfatase 32 129 1.3E-12 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 250 333 6.6E-18 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 Hamap MF_01602 Lipoate-protein ligase A [lplA]. 1 338 59.77 T 28-03-2018 IPR023741 Lipoate-protein ligase A GO:0016979|GO:0018055 KEGG: 00785+6.3.1.20 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 Gene3D G3DSA:3.30.390.50 250 337 1.0E-23 T 28-03-2018 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 SUPERFAMILY SSF82649 248 335 8.37E-25 T 28-03-2018 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 158 5.2E-9 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 1 329 4.0E-141 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 SUPERFAMILY SSF55681 3 247 1.16E-80 T 28-03-2018 WM46_RS24115 506adcc8ee2ef358a302987f5fb0beab 338 Gene3D G3DSA:3.30.930.10 2 249 2.5E-73 T 28-03-2018 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 Gene3D G3DSA:3.40.640.10 171 289 2.7E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 13 397 5.8E-165 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 Pfam PF00202 Aminotransferase class-III 20 394 4.1E-124 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 Gene3D G3DSA:3.90.1150.10 2 170 1.9E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 5 400 7.0E-222 T 28-03-2018 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 PIRSF PIRSF000521 167 400 2.5E-36 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 PIRSF PIRSF000521 26 154 1.2E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 398 45.14 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 SUPERFAMILY SSF53383 12 395 1.3E-125 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 Hamap MF_01173 Succinylornithine transaminase [astC]. 1 406 74.074 T 28-03-2018 IPR026330 Succinylornithine transaminase GO:0006527|GO:0006593|GO:0043825 KEGG: 00330+2.6.1.81 WM46_RS08195 a7651b9a653ebb524c95bb22f6b23c8b 406 Gene3D G3DSA:3.90.1150.10 290 405 3.0E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 PIRSF PIRSF004491 1 311 4.2E-103 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 Gene3D G3DSA:2.40.30.30 180 311 4.9E-40 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 Pfam PF06574 FAD synthetase 12 167 7.7E-57 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 SUPERFAMILY SSF52374 15 175 5.63E-33 T 28-03-2018 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 SMART SM00904 183 307 9.9E-63 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 Gene3D G3DSA:3.40.50.620 1 179 1.6E-48 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 Pfam PF01687 Riboflavin kinase 184 305 2.7E-37 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 SUPERFAMILY SSF82114 174 307 5.89E-44 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 WM46_RS14705 5e3fa1922ccf6556b4fb043fcc541c97 312 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 306 3.0E-119 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 WM46_RS18645 018f43c89b6b2305befc86e9ecaa1b1d 280 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 132 143 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS18645 018f43c89b6b2305befc86e9ecaa1b1d 280 Gene3D G3DSA:3.20.20.70 1 280 8.5E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS18645 018f43c89b6b2305befc86e9ecaa1b1d 280 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 279 2.3E-87 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS18645 018f43c89b6b2305befc86e9ecaa1b1d 280 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 279 3.0E-78 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS18645 018f43c89b6b2305befc86e9ecaa1b1d 280 PIRSF PIRSF001359 1 280 1.9E-85 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS18645 018f43c89b6b2305befc86e9ecaa1b1d 280 SUPERFAMILY SSF51569 3 279 4.4E-85 T 28-03-2018 WM46_RS05435 3a37e82e3fb4de169ce3ac1f8b57ade0 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 9.2E-54 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS05435 3a37e82e3fb4de169ce3ac1f8b57ade0 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 232 3.8E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS05435 3a37e82e3fb4de169ce3ac1f8b57ade0 269 Gene3D G3DSA:3.40.50.1000 1 268 1.0E-33 T 28-03-2018 IPR023214 HAD-like domain WM46_RS05435 3a37e82e3fb4de169ce3ac1f8b57ade0 269 SUPERFAMILY SSF56784 1 263 5.66E-63 T 28-03-2018 IPR023214 HAD-like domain WM46_RS05435 3a37e82e3fb4de169ce3ac1f8b57ade0 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 1.3E-54 T 28-03-2018 IPR023214 HAD-like domain WM46_RS15575 3a062e611ae099792a2dda1aef29745d 385 Gene3D G3DSA:1.10.287.470 121 174 2.2E-5 T 28-03-2018 WM46_RS15575 3a062e611ae099792a2dda1aef29745d 385 Gene3D G3DSA:2.40.50.100 56 120 1.2E-15 T 28-03-2018 WM46_RS15575 3a062e611ae099792a2dda1aef29745d 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 42 258 4.4E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS15575 3a062e611ae099792a2dda1aef29745d 385 SUPERFAMILY SSF111369 46 243 1.44E-24 T 28-03-2018 WM46_RS15575 3a062e611ae099792a2dda1aef29745d 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 34 370 9.7E-57 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS15575 3a062e611ae099792a2dda1aef29745d 385 Gene3D G3DSA:2.40.50.100 175 349 8.3E-7 T 28-03-2018 WM46_RS17600 dbeb287c70ecf10127f42b0c00eb5067 119 Hamap MF_00389 Protein TusC [tusC]. 1 119 35.064 T 28-03-2018 IPR017462 Sulphur relay, TusC/DsrF WM46_RS17600 dbeb287c70ecf10127f42b0c00eb5067 119 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 3 119 1.1E-44 T 28-03-2018 IPR017462 Sulphur relay, TusC/DsrF WM46_RS17600 dbeb287c70ecf10127f42b0c00eb5067 119 SUPERFAMILY SSF75169 1 119 2.5E-33 T 28-03-2018 IPR027396 DsrEFH-like WM46_RS17600 dbeb287c70ecf10127f42b0c00eb5067 119 Pfam PF02635 DsrE/DsrF-like family 2 119 3.0E-22 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein WM46_RS17600 dbeb287c70ecf10127f42b0c00eb5067 119 Gene3D G3DSA:3.40.1260.10 4 117 1.9E-18 T 28-03-2018 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Gene3D G3DSA:3.90.1170.30 1 46 6.9E-14 T 28-03-2018 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Gene3D G3DSA:3.90.1170.30 47 116 2.1E-4 T 28-03-2018 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 406 2.0E-194 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Pfam PF00364 Biotin-requiring enzyme 5 76 4.3E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 176 404 1.9E-81 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Gene3D G3DSA:3.30.559.10 159 404 2.9E-91 T 28-03-2018 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Pfam PF02817 e3 binding domain 114 146 4.9E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 SUPERFAMILY SSF47005 106 151 2.09E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 Gene3D G3DSA:4.10.320.10 117 158 7.0E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 SUPERFAMILY SSF52777 176 405 1.11E-89 T 28-03-2018 WM46_RS10980 ce300f09673de5b2543a22ceebf45037 406 SUPERFAMILY SSF51230 2 95 3.14E-24 T 28-03-2018 IPR011053 Single hybrid motif WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 Gene3D G3DSA:3.30.479.20 149 279 6.0E-48 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 SUPERFAMILY SSF54713 142 281 4.77E-53 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 SUPERFAMILY SSF46934 4 54 2.24E-18 T 28-03-2018 IPR009060 UBA-like GO:0005515 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 282 1.6E-120 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 Gene3D G3DSA:3.30.479.20 58 148 6.9E-15 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 Pfam PF00889 Elongation factor TS 71 263 2.6E-65 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 Hamap MF_00050 Elongation factor Ts [tsf]. 1 280 79.375 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 Gene3D G3DSA:1.10.8.10 1 56 1.0E-23 T 28-03-2018 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS13970 fdd8f1a4e4af76f4b41ec51eea92476b 283 SUPERFAMILY SSF54713 56 139 3.27E-20 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 SUPERFAMILY SSF51735 4 167 8.49E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 Gene3D G3DSA:3.40.50.720 2 169 7.2E-29 T 28-03-2018 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 Gene3D G3DSA:3.90.110.10 171 449 2.4E-67 T 28-03-2018 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 194 206 7.6E-52 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 SUPERFAMILY SSF56327 173 443 8.08E-76 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 199 415 1.1E-34 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 WM46_RS08125 a0648516231d15aa7e077ac07ed0fcbd 451 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 2.1E-76 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS16705 0d46fa14d212fc890fe39f1ee9c5be71 167 Pfam PF13508 Acetyltransferase (GNAT) domain 45 123 1.1E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS16705 0d46fa14d212fc890fe39f1ee9c5be71 167 SUPERFAMILY SSF55729 1 159 6.58E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS16705 0d46fa14d212fc890fe39f1ee9c5be71 167 Gene3D G3DSA:3.40.630.30 3 158 1.6E-19 T 28-03-2018 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 871 0.0 T 28-03-2018 IPR017729 Type VI secretion system, ATPase ClpV1 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 SUPERFAMILY SSF81923 13 124 2.55E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 SUPERFAMILY SSF52540 180 507 1.37E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Pfam PF07724 AAA domain (Cdc48 subfamily) 621 782 2.1E-37 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Gene3D G3DSA:1.10.8.60 362 572 4.3E-40 T 28-03-2018 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 SMART SM01086 788 880 4.1E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 626 644 2.8E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 733 747 2.8E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 671 689 2.8E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 700 718 2.8E-29 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 334 3.6E-7 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Gene3D G3DSA:3.40.50.300 176 361 6.8E-19 T 28-03-2018 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 SMART SM00382 217 362 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 SMART SM00382 622 822 9.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 788 862 1.1E-8 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 SUPERFAMILY SSF52540 571 869 5.09E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Gene3D G3DSA:1.10.1780.10 5 160 1.9E-21 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 656 674 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Gene3D G3DSA:3.40.50.300 589 802 5.5E-26 T 28-03-2018 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 Gene3D G3DSA:1.10.8.60 803 884 6.9E-9 T 28-03-2018 WM46_RS09050 bcf189acdd235d939b9454a9ec6a5c77 902 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 313 325 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 WM46_RS19935 7b5856e8555ca473c96a3d7c1bb8b8e4 141 Pfam PF03610 PTS system fructose IIA component 10 118 1.6E-15 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS19935 7b5856e8555ca473c96a3d7c1bb8b8e4 141 SUPERFAMILY SSF53062 9 129 8.5E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS19935 7b5856e8555ca473c96a3d7c1bb8b8e4 141 Gene3D G3DSA:3.40.50.510 2 141 3.4E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 Pfam PF00691 OmpA family 115 210 1.6E-22 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 ProSitePatterns PS01068 OmpA-like domain. 148 192 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 Gene3D G3DSA:3.30.1330.60 83 220 1.4E-41 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 SUPERFAMILY SSF103088 103 218 1.44E-37 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01021 OMPA domain signature 116 138 4.3E-13 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01021 OMPA domain signature 146 161 4.3E-13 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01021 OMPA domain signature 161 177 4.3E-13 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 161 178 8.3E-8 T 28-03-2018 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 199 219 8.3E-8 T 28-03-2018 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 132 158 8.3E-8 T 28-03-2018 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 179 198 8.3E-8 T 28-03-2018 WM46_RS20545 5a0dffde76d1c16ac14728e1716caa4b 220 Pfam PF13488 Glycine zipper 37 85 2.4E-12 T 28-03-2018 WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 8.3E-295 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 Pfam PF00005 ABC transporter 22 191 2.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 Pfam PF00005 ABC transporter 340 473 5.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 SMART SM00382 31 236 8.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 SMART SM00382 348 522 3.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 Pfam PF12848 ABC transporter 230 306 1.5E-11 T 28-03-2018 IPR032781 ABC-transporter extension domain WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 SUPERFAMILY SSF52540 301 526 8.04E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 Gene3D G3DSA:3.40.50.300 12 289 1.4E-56 T 28-03-2018 WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 Gene3D G3DSA:3.40.50.300 290 551 2.1E-56 T 28-03-2018 WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 SUPERFAMILY SSF52540 11 243 6.73E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14880 a48e14fadfa22dff5b1e0c5bec468431 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 2 325 2.8E-135 T 28-03-2018 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 190 204 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 Gene3D G3DSA:3.40.50.300 115 268 5.5E-25 T 28-03-2018 WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 Gene3D G3DSA:3.40.50.300 269 326 4.5E-7 T 28-03-2018 WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 Pfam PF00437 Type II/IV secretion system protein 61 259 5.4E-41 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 SUPERFAMILY SSF52540 4 325 4.46E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15075 61015ceb3a0b3d8c4f527a2ebd361294 326 Gene3D G3DSA:3.30.450.90 1 97 2.2E-15 T 28-03-2018 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 PIRSF PIRSF000111 1 866 0.0 T 28-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 632 660 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 Gene3D G3DSA:3.40.50.1970 430 643 1.4E-50 T 28-03-2018 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 SUPERFAMILY SSF53720 6 453 8.12E-84 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 Gene3D G3DSA:1.20.1090.10 644 868 1.1E-59 T 28-03-2018 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 Pfam PF00465 Iron-containing alcohol dehydrogenase 457 850 1.2E-114 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 Pfam PF00171 Aldehyde dehydrogenase family 5 280 3.8E-27 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 SUPERFAMILY SSF56796 449 867 2.62E-118 T 28-03-2018 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 Gene3D G3DSA:3.40.605.10 1 229 3.7E-33 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 Gene3D G3DSA:3.40.309.10 230 402 7.1E-26 T 28-03-2018 WM46_RS05730 3c8ecf298b015e1aba2d93e02347d7fb 891 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 720 740 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 Pfam PF00107 Zinc-binding dehydrogenase 152 256 4.7E-29 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 Gene3D G3DSA:3.90.180.10 1 151 6.2E-39 T 28-03-2018 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 Gene3D G3DSA:3.90.180.10 253 326 0.083 T 28-03-2018 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 Gene3D G3DSA:3.40.50.720 152 251 1.7E-17 T 28-03-2018 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 SUPERFAMILY SSF51735 113 272 2.44E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 SUPERFAMILY SSF50129 5 142 1.18E-33 T 28-03-2018 IPR011032 GroES-like WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 2.4E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS21630 6b2d3c81e2f6b79bf276ffb2042fd44e 327 SMART SM00829 11 325 1.3E-29 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS11355 492a576ab2ac091c29a9334953358aa9 196 Gene3D G3DSA:3.30.160.150 19 173 1.7E-47 T 28-03-2018 WM46_RS11355 492a576ab2ac091c29a9334953358aa9 196 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 4 164 26.052 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 WM46_RS11355 492a576ab2ac091c29a9334953358aa9 196 Pfam PF04390 Lipopolysaccharide-assembly 42 159 6.0E-14 T 28-03-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 439 1.5E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 183 195 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 SUPERFAMILY SSF47203 283 442 5.8E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 Gene3D G3DSA:2.40.110.10 179 275 4.0E-21 T 28-03-2018 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 398 417 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 181 275 1.1E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 SUPERFAMILY SSF56645 61 282 6.62E-32 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 WM46_RS22955 748c43abd04aee79a10e0bb1bef8a540 540 Gene3D G3DSA:1.20.140.10 276 447 1.8E-32 T 28-03-2018 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Gene3D G3DSA:2.30.42.10 390 475 4.0E-17 T 28-03-2018 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 SMART SM00228 290 372 1.4E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 SMART SM00228 397 467 3.2E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 PRINTS PR00834 HtrA/DegQ protease family signature 187 211 1.6E-60 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.6E-60 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 PRINTS PR00834 HtrA/DegQ protease family signature 330 342 1.6E-60 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 PRINTS PR00834 HtrA/DegQ protease family signature 146 166 1.6E-60 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 PRINTS PR00834 HtrA/DegQ protease family signature 125 137 1.6E-60 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 1.6E-60 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 288 368 2.1E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 392 464 1.6E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Gene3D G3DSA:2.40.10.10 27 161 6.3E-32 T 28-03-2018 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 SUPERFAMILY SSF50156 272 381 1.33E-22 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 SUPERFAMILY SSF50156 400 471 1.29E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Gene3D G3DSA:2.30.42.10 285 389 2.4E-26 T 28-03-2018 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 SUPERFAMILY SSF50494 18 59 7.27E-65 T 28-03-2018 IPR009003 Peptidase S1, PA clan WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 SUPERFAMILY SSF50494 112 299 7.27E-65 T 28-03-2018 IPR009003 Peptidase S1, PA clan WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Pfam PF13365 Trypsin-like peptidase domain 115 251 1.0E-32 T 28-03-2018 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 40 473 2.0E-166 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 WM46_RS14010 27299fb4aa8b62d298e02daaea0072ed 475 Gene3D G3DSA:2.40.10.10 162 280 9.4E-44 T 28-03-2018 WM46_RS19250 1674f7b456f9a5d7284567906f199851 367 Pfam PF00953 Glycosyl transferase family 4 75 232 5.9E-28 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 WM46_RS19250 1674f7b456f9a5d7284567906f199851 367 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 8 351 2.0E-170 T 28-03-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 WM46_RS19250 1674f7b456f9a5d7284567906f199851 367 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 9 353 28.143 T 28-03-2018 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 WM46_RS00995 48e436f51c941352392c99a5f6643922 395 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 191 219 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS00995 48e436f51c941352392c99a5f6643922 395 SUPERFAMILY SSF56796 22 393 8.5E-114 T 28-03-2018 WM46_RS00995 48e436f51c941352392c99a5f6643922 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 27 387 6.4E-113 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS00995 48e436f51c941352392c99a5f6643922 395 Gene3D G3DSA:1.20.1090.10 203 395 1.2E-57 T 28-03-2018 WM46_RS00995 48e436f51c941352392c99a5f6643922 395 Gene3D G3DSA:3.40.50.1970 27 201 1.6E-42 T 28-03-2018 WM46_RS00995 48e436f51c941352392c99a5f6643922 395 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 278 298 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS22785 601633f2deb705a71d0f0bed4377f82e 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 6.6E-33 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 WM46_RS22785 601633f2deb705a71d0f0bed4377f82e 105 SUPERFAMILY SSF103481 5 103 2.75E-21 T 28-03-2018 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 Hamap MF_01932 AMP nucleosidase [amn]. 3 484 59.318 T 28-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 11 484 1.7E-242 T 28-03-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 Gene3D G3DSA:3.40.50.1580 174 467 8.1E-69 T 28-03-2018 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 Pfam PF01048 Phosphorylase superfamily 267 431 1.9E-18 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 SUPERFAMILY SSF53167 9 484 1.57E-158 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 12 166 1.3E-52 T 28-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 WM46_RS03665 272ae4ed6e8f8b6684997795761d906d 484 Gene3D G3DSA:3.30.1730.10 6 170 9.9E-52 T 28-03-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Gene3D G3DSA:1.10.540.10 1 114 4.1E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 376 5.2E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 SUPERFAMILY SSF56645 1 227 3.8E-51 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Hamap MF_01052 Crotonobetainyl-CoA dehydrogenase [caiA]. 1 380 91.942 T 28-03-2018 IPR023450 Crotonobetainyl-CoA reductase CaiA GO:0009437|GO:0016627|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Gene3D G3DSA:1.20.140.10 216 380 8.1E-46 T 28-03-2018 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 109 1.9E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 SUPERFAMILY SSF47203 226 379 2.74E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 PIRSF PIRSF016578 241 378 8.4E-8 T 28-03-2018 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 PIRSF PIRSF016578 7 84 6.0E-6 T 28-03-2018 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Gene3D G3DSA:2.40.110.10 115 215 8.8E-24 T 28-03-2018 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 215 3.9E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM46_RS14635 fff9138fe6f7d6a24718d4f15dcc3d1b 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 Pfam PF00581 Rhodanese-like domain 138 233 2.3E-13 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 SMART SM00450 136 237 1.3E-24 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 Gene3D G3DSA:3.40.250.10 130 243 5.0E-28 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 Pfam PF12368 Rhodanase C-terminal 246 307 2.0E-18 T 28-03-2018 IPR022111 Rhodanase, C-terminal WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 SUPERFAMILY SSF52821 116 270 6.02E-32 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 Gene3D G3DSA:3.90.1150.10 8 85 0.17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS08885 cefe24fd85bb4d08aa26336059d02819 350 Hamap MF_00469 UPF0176 protein YceA [yceA]. 22 277 39.525 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 SUPERFAMILY SSF103473 18 430 5.75E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 Gene3D G3DSA:1.20.1250.20 17 230 7.7E-26 T 28-03-2018 WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 30 417 1.8E-145 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 Gene3D G3DSA:1.20.1250.20 231 429 3.4E-19 T 28-03-2018 WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 Pfam PF00083 Sugar (and other) transporter 24 221 1.6E-26 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS00305 e5cddd11ac4cad687bada224cdf31545 432 Pfam PF00083 Sugar (and other) transporter 224 419 1.3E-10 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS01635 3513e55fa0a0da53295d7b2ac3308fb9 257 Gene3D G3DSA:3.40.50.300 1 256 9.2E-74 T 28-03-2018 WM46_RS01635 3513e55fa0a0da53295d7b2ac3308fb9 257 SMART SM00382 30 229 5.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS01635 3513e55fa0a0da53295d7b2ac3308fb9 257 PIRSF PIRSF039085 2 257 1.0E-122 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS01635 3513e55fa0a0da53295d7b2ac3308fb9 257 SUPERFAMILY SSF52540 6 251 1.42E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01635 3513e55fa0a0da53295d7b2ac3308fb9 257 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS01635 3513e55fa0a0da53295d7b2ac3308fb9 257 Pfam PF00005 ABC transporter 21 181 5.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 Gene3D G3DSA:3.40.718.10 408 691 1.1E-63 T 28-03-2018 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 PIRSF PIRSF006107 1 713 0.0 T 28-03-2018 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 SUPERFAMILY SSF53659 392 709 5.76E-94 T 28-03-2018 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 Pfam PF01515 Phosphate acetyl/butaryl transferase 391 706 4.4E-128 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 SUPERFAMILY SSF52540 4 240 2.92E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 Pfam PF13500 AAA domain 5 229 8.4E-48 T 28-03-2018 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 Gene3D G3DSA:3.40.50.300 1 230 2.3E-28 T 28-03-2018 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 SUPERFAMILY SSF75138 229 353 3.53E-25 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 406 706 3.7E-138 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 Gene3D G3DSA:3.40.1390.20 231 366 2.2E-27 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like WM46_RS01715 77647886c1a6bac9bbe24432ce45eda8 713 Pfam PF07085 DRTGG domain 233 344 1.6E-29 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 SUPERFAMILY SSF51735 4 173 1.58E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 Gene3D G3DSA:3.40.50.720 1 180 5.7E-35 T 28-03-2018 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 466 3.1E-133 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 SUPERFAMILY SSF48179 177 468 1.26E-130 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 SMART SM01350 179 467 7.5E-222 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PIRSF PIRSF000109 1 468 2.0E-241 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 1.6E-229 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 Gene3D G3DSA:1.20.5.320 435 468 8.7E-22 T 28-03-2018 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 1.5E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 1.5E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 1.5E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 1.5E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 1.5E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 1.5E-89 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 Gene3D G3DSA:1.10.1040.10 181 434 1.2E-110 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS02990 bbbcfdd4d8bdcf23bbc68aa18e71f988 468 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 174 1.3E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 WM46_RS02030 c8f6aaf66b242cdf7ac839ad771d3726 338 SUPERFAMILY SSF55347 156 260 7.63E-11 T 28-03-2018 WM46_RS02030 c8f6aaf66b242cdf7ac839ad771d3726 338 Gene3D G3DSA:3.40.50.720 1 129 5.0E-35 T 28-03-2018 WM46_RS02030 c8f6aaf66b242cdf7ac839ad771d3726 338 Gene3D G3DSA:3.30.360.10 130 338 9.0E-21 T 28-03-2018 WM46_RS02030 c8f6aaf66b242cdf7ac839ad771d3726 338 SUPERFAMILY SSF51735 3 147 2.7E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02030 c8f6aaf66b242cdf7ac839ad771d3726 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 122 5.9E-30 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 PIRSF PIRSF000167 3 454 1.9E-179 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 Pfam PF06969 HemN C-terminal domain 363 431 1.6E-9 T 28-03-2018 IPR010723 HemN, C-terminal WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 SMART SM00729 52 272 6.6E-57 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 Pfam PF04055 Radical SAM superfamily 57 226 6.0E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 Gene3D G3DSA:3.20.20.70 41 353 2.0E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 SUPERFAMILY SSF102114 6 444 1.73E-147 T 28-03-2018 WM46_RS18855 14fb2bed3519a6e08a72aa903483a71f 457 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 6 457 2.5E-236 T 28-03-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 WM46_RS20845 5dbdd5a47c8dfd1b877efe3d2064c531 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 271 1.3E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20845 5dbdd5a47c8dfd1b877efe3d2064c531 277 Gene3D G3DSA:1.10.3720.10 4 261 1.4E-30 T 28-03-2018 WM46_RS20845 5dbdd5a47c8dfd1b877efe3d2064c531 277 SUPERFAMILY SSF161098 66 255 1.01E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20845 5dbdd5a47c8dfd1b877efe3d2064c531 277 TIGRFAM TIGR02790 nickel_nikC: nickel ABC transporter, permease subunit NikC 12 268 7.9E-118 T 28-03-2018 IPR014157 Nickel ABC transporter, permease subunit NikC GO:0015099|GO:0016021 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 30 158 9.1E-43 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 Gene3D G3DSA:2.60.40.10 160 247 3.4E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 PRINTS PR00969 Pili chaperone signature 30 39 3.0E-28 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 PRINTS PR00969 Pili chaperone signature 140 155 3.0E-28 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 PRINTS PR00969 Pili chaperone signature 109 126 3.0E-28 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 PRINTS PR00969 Pili chaperone signature 80 101 3.0E-28 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 PRINTS PR00969 Pili chaperone signature 179 194 3.0E-28 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 Gene3D G3DSA:2.60.40.10 29 159 1.1E-37 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 SUPERFAMILY SSF49354 24 158 1.96E-40 T 28-03-2018 IPR008962 PapD-like WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 184 243 1.6E-12 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24710 70172bf0c2fb952a91371891aaf9e5d3 250 SUPERFAMILY SSF49584 152 246 5.23E-13 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS04670 01bc494d6d279dedd98d56c69b23f9ed 370 Pfam PF04233 Phage Mu protein F like protein 153 273 1.5E-7 T 28-03-2018 IPR006528 Phage head morphogenesis domain WM46_RS04670 01bc494d6d279dedd98d56c69b23f9ed 370 PIRSF PIRSF034565 6 370 9.7E-139 T 28-03-2018 IPR017029 Putative phage head morphogenesis protein WM46_RS14165 b9d131df918c195ced4d6ef215331d5e 173 Gene3D G3DSA:3.40.1000.10 26 173 1.4E-11 T 28-03-2018 WM46_RS00445 1caef748881191365921961d0de4d7a2 454 SUPERFAMILY SSF55604 8 81 9.94E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS00445 1caef748881191365921961d0de4d7a2 454 Pfam PF02378 Phosphotransferase system, EIIC 118 392 8.3E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS00445 1caef748881191365921961d0de4d7a2 454 Gene3D G3DSA:3.30.1360.60 5 82 3.9E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS00445 1caef748881191365921961d0de4d7a2 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS00445 1caef748881191365921961d0de4d7a2 454 Pfam PF00367 phosphotransferase system, EIIB 11 39 4.6E-10 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 2 1295 21.592 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF82697 1 152 8.37E-54 T 28-03-2018 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Gene3D G3DSA:3.30.1330.10 220 425 2.0E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Gene3D G3DSA:3.30.1330.10 612 813 1.2E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Gene3D G3DSA:3.30.1330.10 183 219 0.0019 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF56042 818 1033 7.78E-57 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1293 0.0 T 28-03-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 432 588 1.2E-26 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 826 966 1.2E-13 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SMART SM01211 1039 1294 1.9E-155 T 28-03-2018 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF55326 221 428 1.53E-64 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Gene3D G3DSA:3.90.650.10 426 609 1.4E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Gene3D G3DSA:3.90.650.10 821 994 9.9E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Gene3D G3DSA:3.40.50.880 1038 1294 4.2E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF56042 432 615 7.92E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1039 1292 3.3E-102 T 28-03-2018 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF109736 155 220 1.27E-21 T 28-03-2018 WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF55326 618 816 8.37E-67 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00465 610d9d7cc3fa82cf128fe13e0330d40f 1295 SUPERFAMILY SSF52317 1035 1293 2.98E-98 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 SUPERFAMILY SSF100934 504 615 2.16E-36 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 SUPERFAMILY SSF100920 384 535 7.46E-50 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 Gene3D G3DSA:3.30.420.40 209 357 2.0E-39 T 28-03-2018 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 SUPERFAMILY SSF53067 19 196 1.83E-50 T 28-03-2018 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 SUPERFAMILY SSF53067 200 377 2.98E-52 T 28-03-2018 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 615 1.7E-270 T 28-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 Gene3D G3DSA:3.30.420.40 20 208 4.7E-56 T 28-03-2018 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 Gene3D G3DSA:2.60.34.10 387 528 5.9E-49 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 Pfam PF00012 Hsp70 protein 21 600 1.0E-202 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 Gene3D G3DSA:1.20.1270.10 529 615 2.6E-12 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 616 45.402 T 28-03-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 329 345 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 385 404 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 20 33 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 48 60 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 360 380 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 466 482 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 152 172 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS00640 ec3aa921fa69913cf85c88b47b2b189c 616 PRINTS PR00301 70kDa heat shock protein signature 211 221 1.4E-54 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 SUPERFAMILY SSF46785 3 73 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 Pfam PF07729 FCD domain 80 200 1.7E-8 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 SMART SM00345 11 69 4.8E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 69 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 Gene3D G3DSA:1.10.10.10 1 65 5.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 Gene3D G3DSA:1.20.120.530 66 216 1.1E-12 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23575 7bfffad01f14e37ed5b02462cb37a579 216 SUPERFAMILY SSF48008 80 206 2.3E-6 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS09140 889d12b918fb356e259a9442314565ce 212 Pfam PF08362 YcdC-like protein, C-terminal region 70 211 5.8E-59 T 28-03-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 TIGRFAM TIGR03613 RutR: pyrimidine utilization regulatory protein R 11 211 6.9E-113 T 28-03-2018 IPR019915 Transcription regulator, pyrimidine utilisation, RutR WM46_RS09140 889d12b918fb356e259a9442314565ce 212 Gene3D G3DSA:1.10.357.10 84 212 4.9E-25 T 28-03-2018 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 5.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 Gene3D G3DSA:1.10.10.60 1 44 3.9E-13 T 28-03-2018 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 SUPERFAMILY SSF46689 16 90 4.49E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS09140 889d12b918fb356e259a9442314565ce 212 SUPERFAMILY SSF48498 87 211 2.36E-42 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS09140 889d12b918fb356e259a9442314565ce 212 Gene3D G3DSA:1.10.260.40 45 83 1.4E-10 T 28-03-2018 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 Pfam PF00334 Nucleoside diphosphate kinase 4 137 3.1E-53 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 Gene3D G3DSA:3.30.70.141 2 142 5.7E-52 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 SUPERFAMILY SSF54919 1 140 1.83E-57 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 3.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 3.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 3.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.7E-39 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 SMART SM00562 3 140 2.1E-83 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS00685 ea162cb059970fd12a614050e6b453dd 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 34.209 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF56784 575 823 8.25E-60 T 28-03-2018 IPR023214 HAD-like domain WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF56784 518 538 8.25E-60 T 28-03-2018 IPR023214 HAD-like domain WM46_RS12320 68c060b6045faa211300db0de950036b 833 Pfam PF00403 Heavy-metal-associated domain 8 61 9.6E-10 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Pfam PF00403 Heavy-metal-associated domain 104 158 4.5E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM46_RS12320 68c060b6045faa211300db0de950036b 833 ProSitePatterns PS01047 Heavy-metal-associated domain. 104 133 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 WM46_RS12320 68c060b6045faa211300db0de950036b 833 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF55008 2 67 1.83E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Pfam PF00122 E1-E2 ATPase 319 499 1.1E-51 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Pfam PF00702 haloacid dehalogenase-like hydrolase 517 731 3.6E-49 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 689 705 1.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 748 773 1.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 717 733 1.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Gene3D G3DSA:3.30.70.100 94 166 2.3E-20 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Gene3D G3DSA:1.20.1110.10 286 543 4.1E-45 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Gene3D G3DSA:3.30.70.100 1 73 3.0E-14 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Gene3D G3DSA:3.40.50.1000 644 782 3.6E-47 T 28-03-2018 IPR023214 HAD-like domain WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 740 752 2.3E-26 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 664 674 2.3E-26 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 520 534 2.3E-26 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 717 736 2.3E-26 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 368 382 2.3E-26 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 653 2.3E-26 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 232 826 8.8E-193 T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 ProSitePatterns PS01229 Hypothetical cof family signature 2. 717 739 - T 28-03-2018 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF81665 285 322 9.15E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF81665 766 785 9.15E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF81665 419 514 9.15E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 Gene3D G3DSA:3.40.1110.10 544 643 1.9E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 522 528 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF55008 100 164 1.31E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM46_RS12320 68c060b6045faa211300db0de950036b 833 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 251 826 6.6E-182 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 SUPERFAMILY SSF81653 321 418 7.45E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 WM46_RS12320 68c060b6045faa211300db0de950036b 833 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 290 794 4.1E-89 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 172 1.8E-16 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Pfam PF00009 Elongation factor Tu GTP binding domain 2 181 1.1E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 PRINTS PR00315 GTP-binding elongation factor signature 90 101 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 PRINTS PR00315 GTP-binding elongation factor signature 126 135 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 PRINTS PR00315 GTP-binding elongation factor signature 6 19 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 PRINTS PR00315 GTP-binding elongation factor signature 74 84 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 PRINTS PR00315 GTP-binding elongation factor signature 49 57 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 SUPERFAMILY SSF54980 292 370 1.73E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Pfam PF00679 Elongation factor G C-terminus 399 482 2.4E-19 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Gene3D G3DSA:2.40.30.10 188 287 8.1E-27 T 28-03-2018 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Gene3D G3DSA:3.40.50.300 1 185 2.2E-36 T 28-03-2018 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Gene3D G3DSA:3.30.70.870 288 367 1.2E-27 T 28-03-2018 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Gene3D G3DSA:3.30.70.240 390 549 4.1E-25 T 28-03-2018 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 TIGRFAM TIGR01393 lepA: elongation factor 4 2 594 7.5E-302 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 SUPERFAMILY SSF52540 2 235 6.88E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 SUPERFAMILY SSF54980 399 493 5.28E-24 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Pfam PF03144 Elongation factor Tu domain 2 205 275 1.4E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 1.4E-49 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal WM46_RS00395 4bffa9b274b523c817361f71a5799550 599 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 307.102 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 WM46_RS09770 aa5bfd08aff854d8b1ccf7b8e4b53b94 182 SUPERFAMILY SSF55166 68 182 3.4E-32 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM46_RS09770 aa5bfd08aff854d8b1ccf7b8e4b53b94 182 Gene3D G3DSA:3.30.1380.10 56 182 1.4E-22 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM46_RS09770 aa5bfd08aff854d8b1ccf7b8e4b53b94 182 Pfam PF05951 Bacterial protein of unknown function (DUF882) 34 182 7.5E-60 T 28-03-2018 IPR010275 Protein of unknown function DUF882 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 Pfam PF08331 Domain of unknown function (DUF1730) 62 140 1.1E-24 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 Gene3D G3DSA:3.30.70.20 200 371 4.8E-11 T 28-03-2018 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 SUPERFAMILY SSF46548 139 256 2.56E-18 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 14 348 1.0E-150 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 Pfam PF13484 4Fe-4S double cluster binding domain 192 256 1.2E-18 T 28-03-2018 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 7 315 50.899 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS22855 155c54cae6029d8eed51153a36f134b5 379 Gene3D G3DSA:3.30.70.20 123 199 7.2E-4 T 28-03-2018 WM46_RS07130 5bea0dad91ed8d225938a96399b77531 133 ProSitePatterns PS00380 Rhodanese signature 1. 55 66 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 WM46_RS07130 5bea0dad91ed8d225938a96399b77531 133 Pfam PF00581 Rhodanese-like domain 52 123 1.4E-6 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS07130 5bea0dad91ed8d225938a96399b77531 133 SUPERFAMILY SSF52821 20 127 5.5E-19 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS07130 5bea0dad91ed8d225938a96399b77531 133 Gene3D G3DSA:3.40.250.10 26 132 3.5E-17 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS13565 ef23348115706f6bc39a69c2432b943a 730 Gene3D G3DSA:3.40.50.300 456 612 2.3E-5 T 28-03-2018 WM46_RS13565 ef23348115706f6bc39a69c2432b943a 730 Pfam PF05272 Virulence-associated protein E 426 618 8.3E-71 T 28-03-2018 IPR007936 Virulence-associated E WM46_RS20900 250263fdfbe3fa24dc2c250b6c8b210b 123 Gene3D G3DSA:1.20.1290.10 7 123 1.0E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS20900 250263fdfbe3fa24dc2c250b6c8b210b 123 SUPERFAMILY SSF69118 3 121 2.09E-34 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS20900 250263fdfbe3fa24dc2c250b6c8b210b 123 Pfam PF02627 Carboxymuconolactone decarboxylase family 33 118 1.4E-23 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS13770 751a106a1edc352a89223a342e4b8609 266 SUPERFAMILY SSF56219 44 260 3.4E-26 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS13770 751a106a1edc352a89223a342e4b8609 266 Gene3D G3DSA:3.60.10.10 35 260 1.3E-16 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS13770 751a106a1edc352a89223a342e4b8609 266 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 49 252 4.4E-9 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS13770 751a106a1edc352a89223a342e4b8609 266 Hamap MF_01119 UPF0294 protein YafD [yafD]. 1 260 53.985 T 28-03-2018 IPR022958 Uncharacterised protein family UPF0294 WM46_RS08375 2743019b04e90dad0ec2474e452d47f6 167 SUPERFAMILY SSF55826 10 163 6.28E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS08375 2743019b04e90dad0ec2474e452d47f6 167 Pfam PF04073 Aminoacyl-tRNA editing domain 30 154 1.4E-24 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS08375 2743019b04e90dad0ec2474e452d47f6 167 Gene3D G3DSA:3.90.960.10 4 167 4.1E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS03355 373697ade97f14b9727020fc1c158ed8 180 Pfam PF06890 Bacteriophage Mu Gp45 protein 5 158 1.5E-36 T 28-03-2018 IPR014462 Phage-associated protein Gp45 WM46_RS03355 373697ade97f14b9727020fc1c158ed8 180 PIRSF PIRSF012337 1 178 4.1E-36 T 28-03-2018 IPR014462 Phage-associated protein Gp45 WM46_RS04740 4841353deaa0fa7af6fdf47a4442771e 175 Pfam PF04383 KilA-N domain 9 113 1.5E-14 T 28-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding WM46_RS04740 4841353deaa0fa7af6fdf47a4442771e 175 SMART SM01252 9 116 2.1E-22 T 28-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 SUPERFAMILY SSF47831 146 254 7.98E-18 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Gene3D G3DSA:3.20.20.60 390 421 6.8E-8 T 28-03-2018 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 296 307 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 SUPERFAMILY SSF55594 5 89 1.31E-15 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Pfam PF00391 PEP-utilising enzyme, mobile domain 264 337 1.3E-14 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 SUPERFAMILY SSF51621 366 661 1.1E-95 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 689 829 8.6E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Pfam PF00381 PTS HPr component phosphorylation site 6 84 4.0E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 559 574 1.4E-20 T 28-03-2018 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 612 624 1.4E-20 T 28-03-2018 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 405 424 1.4E-20 T 28-03-2018 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 576 591 1.4E-20 T 28-03-2018 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Gene3D G3DSA:3.40.930.10 684 831 7.2E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Gene3D G3DSA:3.20.20.60 422 655 3.2E-67 T 28-03-2018 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 SUPERFAMILY SSF52009 236 355 1.03E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 363 653 9.3E-111 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Gene3D G3DSA:1.10.274.10 146 255 4.5E-18 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Pfam PF05524 PEP-utilising enzyme, N-terminal 141 237 3.2E-10 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 SUPERFAMILY SSF55804 689 828 1.01E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Gene3D G3DSA:3.30.1340.10 3 85 4.7E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 Gene3D G3DSA:3.50.30.10 256 389 3.5E-20 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 559 577 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 WM46_RS20945 20fb83d21ac9cc2cf679580c5dc13424 833 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 181 677 2.2E-141 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 SUPERFAMILY SSF56176 5 225 3.97E-46 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 478 4.4E-19 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 Pfam PF01565 FAD binding domain 51 190 1.1E-32 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 Gene3D G3DSA:3.30.465.10 102 227 7.1E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 Gene3D G3DSA:1.10.45.10 441 479 1.2E-7 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 SUPERFAMILY SSF55103 204 481 3.27E-24 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 WM46_RS25170 89d6d26439e3e0b62fb7d2a749d2f30e 484 Gene3D G3DSA:3.30.43.10 2 101 1.4E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 SUPERFAMILY SSF53335 137 244 1.79E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 118 244 4.6E-49 T 28-03-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 266 662 5.1E-155 T 28-03-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 7 657 28.205 T 28-03-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 Gene3D G3DSA:3.40.50.150 9 252 2.5E-83 T 28-03-2018 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 Pfam PF01266 FAD dependent oxidoreductase 267 632 6.6E-45 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 Gene3D G3DSA:3.50.50.60 254 669 1.0E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 SUPERFAMILY SSF51905 571 662 9.5E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01530 d498007619df25dd96ed0e62910ef9ae 670 SUPERFAMILY SSF51905 267 478 9.5E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 558 1.3E-107 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 1.2E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 586 3.7E-277 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 Gene3D G3DSA:2.40.50.140 1 108 1.6E-26 T 28-03-2018 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 5.5E-17 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 Gene3D G3DSA:3.30.930.10 131 586 5.5E-102 T 28-03-2018 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 SUPERFAMILY SSF50249 1 105 2.48E-34 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 584 33.637 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 SUPERFAMILY SSF55261 288 419 1.13E-47 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 SUPERFAMILY SSF55681 108 287 4.02E-105 T 28-03-2018 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 SUPERFAMILY SSF55681 420 584 4.02E-105 T 28-03-2018 WM46_RS04280 08626a46a4d77b9dd1aeab4b12538786 590 Pfam PF02938 GAD domain 307 406 4.3E-32 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82693 138 182 1.62E-23 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82693 274 330 1.62E-23 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Gene3D G3DSA:1.20.1640.10 820 1030 2.5E-37 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 9.8E-110 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82693 39 132 1.1E-25 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Gene3D G3DSA:1.20.1640.10 290 510 3.5E-43 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82866 296 497 2.75E-48 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Gene3D G3DSA:3.30.70.1440 673 769 2.4E-21 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82714 182 272 7.06E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82693 566 672 8.89E-30 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1034 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Gene3D G3DSA:3.30.2090.10 180 275 3.7E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Gene3D G3DSA:3.30.70.1430 38 141 5.7E-28 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82714 723 809 1.44E-23 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 Gene3D G3DSA:3.30.70.1430 568 672 1.0E-24 T 28-03-2018 WM46_RS00900 5de462ffc96400923a50a40f4b819895 1037 SUPERFAMILY SSF82866 807 1030 2.35E-44 T 28-03-2018 WM46_RS12190 aa5a510bc65c8d5804b4ff90236f0356 70 SUPERFAMILY SSF55174 7 68 7.59E-20 T 28-03-2018 WM46_RS12190 aa5a510bc65c8d5804b4ff90236f0356 70 Pfam PF13275 S4 domain 9 68 2.3E-24 T 28-03-2018 WM46_RS12190 aa5a510bc65c8d5804b4ff90236f0356 70 Gene3D G3DSA:3.10.290.10 1 70 6.1E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 Pfam PF09397 Ftsk gamma domain 1272 1332 4.0E-28 T 28-03-2018 IPR018541 FtsK gamma domain WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 SUPERFAMILY SSF46785 1270 1334 5.26E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 Pfam PF01580 FtsK/SpoIIIE family 956 1169 2.7E-75 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 SMART SM00843 1270 1335 3.6E-42 T 28-03-2018 IPR018541 FtsK gamma domain WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 Gene3D G3DSA:1.10.10.10 1272 1326 5.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 SUPERFAMILY SSF52540 930 1242 4.91E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 Gene3D G3DSA:3.40.50.300 666 1209 4.8E-55 T 28-03-2018 WM46_RS09940 824180276f50820b20d40bcd19705a73 1337 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 39 210 3.9E-41 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SMART SM00316 620 690 3.6E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF46915 226 325 1.44E-25 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 2.8E-18 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF01138 3' exoribonuclease family, domain 1 324 456 3.7E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 693 30.476 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Gene3D G3DSA:2.40.50.140 617 698 1.6E-26 T 28-03-2018 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Gene3D G3DSA:3.30.230.70 317 544 5.2E-58 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF55666 450 547 1.96E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF00575 S1 RNA binding domain 619 690 2.8E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Gene3D G3DSA:3.30.1370.10 554 616 1.6E-13 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 PIRSF PIRSF005499 2 711 6.6E-302 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Gene3D G3DSA:1.10.10.400 249 316 6.2E-20 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Gene3D G3DSA:3.30.230.70 13 248 1.0E-53 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF03725 3' exoribonuclease family, domain 2 460 527 1.7E-4 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 2.5E-14 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF54791 554 622 2.81E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 691 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SMART SM00322 552 617 4.2E-12 T 28-03-2018 IPR004087 K Homology domain GO:0003676 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF54211 4 144 1.32E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF50249 608 693 1.39E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF00013 KH domain 556 614 8.0E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 320 8.7E-26 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF55666 145 235 3.8E-31 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS16745 a30af9d136581e7ab2c6b0d9d4d308d2 711 SUPERFAMILY SSF54211 301 492 2.43E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS16655 50780236fb67b982e751468561ec0574 287 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 283 5.0E-114 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS16655 50780236fb67b982e751468561ec0574 287 SUPERFAMILY SSF53790 12 232 4.97E-83 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS16655 50780236fb67b982e751468561ec0574 287 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 213 1.9E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS16655 50780236fb67b982e751468561ec0574 287 PIRSF PIRSF005917 1 287 9.3E-107 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS16655 50780236fb67b982e751468561ec0574 287 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 234 38.214 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS16655 50780236fb67b982e751468561ec0574 287 Gene3D G3DSA:3.30.950.10 122 237 3.5E-41 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS16655 50780236fb67b982e751468561ec0574 287 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS16655 50780236fb67b982e751468561ec0574 287 Gene3D G3DSA:3.40.1010.10 11 121 1.5E-44 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 Gene3D G3DSA:3.20.20.70 8 341 7.1E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 338 6.6E-78 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 SMART SM01240 7 344 6.5E-138 T 28-03-2018 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 176 188 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 Hamap MF_00596 GMP reductase [guaC]. 1 345 55.492 T 28-03-2018 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 SUPERFAMILY SSF51412 6 336 4.97E-99 T 28-03-2018 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 PIRSF PIRSF000235 1 347 1.1E-197 T 28-03-2018 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 WM46_RS14315 1e12db472754b0f4fdf5702bd25fa917 347 TIGRFAM TIGR01305 GMP_reduct_1: guanosine monophosphate reductase 2 344 1.2E-207 T 28-03-2018 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: R-HSA-74217 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Gene3D G3DSA:3.30.365.10 794 956 3.7E-43 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 TIGRFAM TIGR03313 Se_sel_red_Mo: probable selenate reductase, molybdenum-binding subunit 5 955 0.0 T 28-03-2018 IPR017699 Molybdenum-binding protein YgfN/XdhD WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 SUPERFAMILY SSF47741 84 188 3.14E-15 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 187 297 1.4E-29 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Gene3D G3DSA:3.30.365.10 364 469 1.4E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 SUPERFAMILY SSF56003 301 318 1.27E-167 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 SUPERFAMILY SSF56003 354 955 1.27E-167 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Gene3D G3DSA:3.30.365.10 646 793 2.3E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 SMART SM01008 186 298 5.2E-35 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Gene3D G3DSA:3.90.1170.50 180 299 2.7E-26 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 355 893 4.8E-150 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Gene3D G3DSA:1.10.150.120 73 179 2.9E-12 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Gene3D G3DSA:3.30.365.10 470 638 4.1E-37 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 SUPERFAMILY SSF54665 164 317 4.58E-45 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 Pfam PF01799 [2Fe-2S] binding domain 73 144 7.0E-8 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 PIRSF PIRSF000127 51 146 1.1 T 28-03-2018 IPR016208 Aldehyde oxidase/xanthine dehydrogenase GO:0005506|GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 PIRSF PIRSF000127 355 947 2.4E-68 T 28-03-2018 IPR016208 Aldehyde oxidase/xanthine dehydrogenase GO:0005506|GO:0016491|GO:0055114 WM46_RS24310 99fe0f0874f4adbfb6dd4c91dda8d71d 956 PIRSF PIRSF000127 139 344 6.0E-16 T 28-03-2018 IPR016208 Aldehyde oxidase/xanthine dehydrogenase GO:0005506|GO:0016491|GO:0055114 WM46_RS11805 82abff8eb95c77f57309825335538634 727 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 37 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS11805 82abff8eb95c77f57309825335538634 727 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 74 727 5.0E-117 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS11805 82abff8eb95c77f57309825335538634 727 SUPERFAMILY SSF56935 29 34 4.76E-98 T 28-03-2018 WM46_RS11805 82abff8eb95c77f57309825335538634 727 SUPERFAMILY SSF56935 64 727 4.76E-98 T 28-03-2018 WM46_RS11805 82abff8eb95c77f57309825335538634 727 Gene3D G3DSA:2.170.130.10 20 185 2.5E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS11805 82abff8eb95c77f57309825335538634 727 Pfam PF00593 TonB dependent receptor 281 725 1.1E-33 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS11805 82abff8eb95c77f57309825335538634 727 Gene3D G3DSA:2.40.170.20 186 727 1.1E-61 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS11805 82abff8eb95c77f57309825335538634 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 73 168 4.5E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS14410 930686a9079d7754e52c07a3331b29ac 588 Gene3D G3DSA:3.90.1310.10 36 235 7.8E-44 T 28-03-2018 WM46_RS14410 930686a9079d7754e52c07a3331b29ac 588 SUPERFAMILY SSF56519 63 233 3.53E-46 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM46_RS14410 930686a9079d7754e52c07a3331b29ac 588 SUPERFAMILY SSF56601 235 563 1.16E-86 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS14410 930686a9079d7754e52c07a3331b29ac 588 Gene3D G3DSA:3.40.710.10 236 585 1.0E-78 T 28-03-2018 WM46_RS14410 930686a9079d7754e52c07a3331b29ac 588 Pfam PF03717 Penicillin-binding Protein dimerisation domain 69 220 6.8E-20 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM46_RS14410 930686a9079d7754e52c07a3331b29ac 588 Pfam PF00905 Penicillin binding protein transpeptidase domain 260 554 7.3E-84 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 SUPERFAMILY SSF52172 1 173 3.13E-38 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 SMART SM00862 145 220 7.6E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 Pfam PF00072 Response regulator receiver domain 3 112 3.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 SMART SM00448 1 112 5.9E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 Gene3D G3DSA:1.10.10.10 119 223 4.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08495 5a840f65abc15b20b41fff964dc4cdcf 223 Gene3D G3DSA:3.40.50.2300 1 118 5.7E-34 T 28-03-2018 WM46_RS20395 69ddf6677983094e134b19368c4ae8d3 324 Pfam PF03466 LysR substrate binding domain 93 303 1.8E-18 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS20395 69ddf6677983094e134b19368c4ae8d3 324 Gene3D G3DSA:1.10.10.10 1 88 3.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20395 69ddf6677983094e134b19368c4ae8d3 324 Gene3D G3DSA:3.40.190.10 171 278 4.2E-19 T 28-03-2018 WM46_RS20395 69ddf6677983094e134b19368c4ae8d3 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.5E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20395 69ddf6677983094e134b19368c4ae8d3 324 SUPERFAMILY SSF53850 94 308 3.44E-23 T 28-03-2018 WM46_RS20395 69ddf6677983094e134b19368c4ae8d3 324 SUPERFAMILY SSF46785 4 115 2.01E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01510 3a9a783e72cf287d0359de73477a7cba 274 Pfam PF03411 Penicillin-insensitive murein endopeptidase 36 270 2.0E-93 T 28-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 WM46_RS01510 3a9a783e72cf287d0359de73477a7cba 274 SUPERFAMILY SSF55166 21 272 1.26E-101 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM46_RS01510 3a9a783e72cf287d0359de73477a7cba 274 Hamap MF_01623 Penicillin-insensitive murein endopeptidase [mepA]. 1 274 69.932 T 28-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 WM46_RS01510 3a9a783e72cf287d0359de73477a7cba 274 Gene3D G3DSA:3.30.1380.10 20 274 1.2E-96 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM46_RS01510 3a9a783e72cf287d0359de73477a7cba 274 PIRSF PIRSF018455 1 274 8.9E-120 T 28-03-2018 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 WM46_RS04955 97b3193f3dc0e67afc431b3636b7b6db 266 Pfam PF03609 PTS system sorbose-specific iic component 6 237 2.4E-75 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS04955 97b3193f3dc0e67afc431b3636b7b6db 266 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 266 1.2E-128 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS08440 f9a8c307195edeab8edf603ee3d3362d 500 SMART SM00267 323 499 1.5E-49 T 28-03-2018 IPR000160 GGDEF domain WM46_RS08440 f9a8c307195edeab8edf603ee3d3362d 500 Gene3D G3DSA:3.30.70.270 327 500 2.9E-51 T 28-03-2018 WM46_RS08440 f9a8c307195edeab8edf603ee3d3362d 500 SUPERFAMILY SSF55073 339 498 1.33E-44 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS08440 f9a8c307195edeab8edf603ee3d3362d 500 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 332 498 1.3E-46 T 28-03-2018 IPR000160 GGDEF domain WM46_RS08440 f9a8c307195edeab8edf603ee3d3362d 500 Pfam PF00990 Diguanylate cyclase, GGDEF domain 334 495 6.8E-42 T 28-03-2018 IPR000160 GGDEF domain WM46_RS10765 269be40da6b98accf52c6171e2938604 347 Gene3D G3DSA:3.40.50.10800 118 208 1.0E-18 T 28-03-2018 WM46_RS10765 269be40da6b98accf52c6171e2938604 347 SUPERFAMILY SSF142754 29 341 1.44E-106 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 WM46_RS10765 269be40da6b98accf52c6171e2938604 347 Pfam PF02445 Quinolinate synthetase A protein 31 340 3.5E-102 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 WM46_RS10765 269be40da6b98accf52c6171e2938604 347 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 23 342 4.1E-124 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 WM46_RS10765 269be40da6b98accf52c6171e2938604 347 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 347 70.943 T 28-03-2018 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 WM46_RS10765 269be40da6b98accf52c6171e2938604 347 Gene3D G3DSA:3.40.50.10800 25 110 6.0E-18 T 28-03-2018 WM46_RS10765 269be40da6b98accf52c6171e2938604 347 Gene3D G3DSA:3.40.50.10800 209 323 6.8E-31 T 28-03-2018 WM46_RS23885 baecd79306f68d7debf0c3c9c07774e7 355 SUPERFAMILY SSF111369 177 253 2.62E-6 T 28-03-2018 WM46_RS23885 baecd79306f68d7debf0c3c9c07774e7 355 Gene3D G3DSA:2.40.50.100 194 294 0.0065 T 28-03-2018 WM46_RS23885 baecd79306f68d7debf0c3c9c07774e7 355 Gene3D G3DSA:1.10.287.470 118 193 1.9E-7 T 28-03-2018 WM46_RS23885 baecd79306f68d7debf0c3c9c07774e7 355 SUPERFAMILY SSF111369 44 167 9.02E-11 T 28-03-2018 WM46_RS23885 baecd79306f68d7debf0c3c9c07774e7 355 Gene3D G3DSA:2.40.50.100 45 117 1.3E-13 T 28-03-2018 WM46_RS23885 baecd79306f68d7debf0c3c9c07774e7 355 Pfam PF13533 Biotin-lipoyl like 45 89 5.6E-11 T 28-03-2018 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 SUPERFAMILY SSF50104 2 114 5.11E-48 T 28-03-2018 IPR008991 Translation protein SH3-like domain WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 30.618 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 PIRSF PIRSF002191 1 115 2.0E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 Pfam PF01245 Ribosomal protein L19 3 113 5.5E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00200 70d6be53964bf5909fa86ec2a696a175 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.7E-53 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS14470 7d9b967ed5a4c3e4cf4ff5b9eeb63bcf 201 SUPERFAMILY SSF52016 3 193 2.35E-61 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS14470 7d9b967ed5a4c3e4cf4ff5b9eeb63bcf 201 Pfam PF00694 Aconitase C-terminal domain 3 126 8.6E-40 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14470 7d9b967ed5a4c3e4cf4ff5b9eeb63bcf 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 200 44.911 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 WM46_RS14470 7d9b967ed5a4c3e4cf4ff5b9eeb63bcf 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 3 189 3.6E-100 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 WM46_RS14470 7d9b967ed5a4c3e4cf4ff5b9eeb63bcf 201 Gene3D G3DSA:3.20.19.10 1 177 5.8E-51 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 Gene3D G3DSA:3.30.565.10 385 558 1.9E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 Gene3D G3DSA:3.30.450.40 233 374 9.5E-9 T 28-03-2018 IPR029016 GAF domain-like WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 SUPERFAMILY SSF55874 424 557 6.3E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 Pfam PF13185 GAF domain 244 352 2.4E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 SMART SM00065 218 365 3.1E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 Pfam PF07694 5TMR of 5TMR-LYT 28 196 3.9E-59 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 SUPERFAMILY SSF55781 243 359 3.27E-9 T 28-03-2018 IPR029016 GAF domain-like WM46_RS02605 33be1b87ccff93c8384c346abb2a0309 562 Pfam PF06580 Histidine kinase 371 448 1.1E-25 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 SUPERFAMILY SSF51261 468 619 1.05E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS15325 d409734625e581f2a2cf97be47085003 625 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 617 2.4E-215 T 28-03-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 Gene3D G3DSA:2.70.70.10 463 623 1.1E-55 T 28-03-2018 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 Gene3D G3DSA:3.30.1360.60 4 80 7.6E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 Pfam PF02378 Phosphotransferase system, EIIC 108 392 4.1E-28 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 476 596 1.4E-42 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 538 550 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 SUPERFAMILY SSF55604 5 81 8.11E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 475 600 8.7E-48 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS15325 d409734625e581f2a2cf97be47085003 625 Pfam PF00367 phosphotransferase system, EIIB 9 41 5.7E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 Pfam PF08218 Citrate lyase ligase C-terminal domain 147 333 2.4E-80 T 28-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 PIRSF PIRSF005751 1 351 7.1E-137 T 28-03-2018 IPR005216 Citrate lyase ligase GO:0008771 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 SUPERFAMILY SSF55729 39 119 1.08E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 Gene3D G3DSA:3.40.50.620 130 337 7.1E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 147 204 4.1E-11 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 SMART SM00764 147 333 1.8E-133 T 28-03-2018 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 TIGRFAM TIGR00124 cit_ly_ligase: [citrate (pro-3S)-lyase] ligase 7 337 1.1E-166 T 28-03-2018 IPR005216 Citrate lyase ligase GO:0008771 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 SUPERFAMILY SSF52374 144 335 2.15E-24 T 28-03-2018 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 121 338 4.0E-117 T 28-03-2018 WM46_RS11475 24d518c7e50efb428761d7aa89009409 358 Gene3D G3DSA:3.40.630.30 15 129 6.4E-7 T 28-03-2018 WM46_RS14985 773fc83c219b4093e77256b382ebe1c3 425 SUPERFAMILY SSF51735 159 336 8.76E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS14985 773fc83c219b4093e77256b382ebe1c3 425 Pfam PF00107 Zinc-binding dehydrogenase 186 329 8.1E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS14985 773fc83c219b4093e77256b382ebe1c3 425 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 97 4.6E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS14985 773fc83c219b4093e77256b382ebe1c3 425 SUPERFAMILY SSF50129 3 188 1.95E-24 T 28-03-2018 IPR011032 GroES-like WM46_RS14985 773fc83c219b4093e77256b382ebe1c3 425 Gene3D G3DSA:3.40.50.720 153 343 4.4E-17 T 28-03-2018 WM46_RS14985 773fc83c219b4093e77256b382ebe1c3 425 Gene3D G3DSA:3.90.180.10 1 152 6.0E-19 T 28-03-2018 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 354 1.9E-122 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 Gene3D G3DSA:1.20.1090.10 173 362 2.1E-68 T 28-03-2018 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 SUPERFAMILY SSF56796 4 356 5.76E-118 T 28-03-2018 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 358 43.389 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 Gene3D G3DSA:3.40.50.1970 4 172 2.4E-50 T 28-03-2018 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 Pfam PF01761 3-dehydroquinate synthase 67 325 1.0E-108 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM46_RS17775 2121b493db8d8c4d4fea02d6c8e498d9 362 PIRSF PIRSF001455 10 361 4.1E-107 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 WM46_RS22380 2daf927c2602e5216f1b1da10ceb112c 379 Hamap MF_01167 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase [arnB]. 1 379 69.518 T 28-03-2018 IPR022850 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase, ArnB GO:0008483 KEGG: 00520+2.6.1.87 WM46_RS22380 2daf927c2602e5216f1b1da10ceb112c 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 373 2.9E-129 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS22380 2daf927c2602e5216f1b1da10ceb112c 379 Gene3D G3DSA:3.40.640.10 1 245 1.3E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS22380 2daf927c2602e5216f1b1da10ceb112c 379 SUPERFAMILY SSF53383 4 376 1.24E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS22380 2daf927c2602e5216f1b1da10ceb112c 379 PIRSF PIRSF000390 1 379 2.3E-110 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS22380 2daf927c2602e5216f1b1da10ceb112c 379 Gene3D G3DSA:3.90.1150.10 246 379 1.2E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 SMART SM00341 210 289 5.0E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 SUPERFAMILY SSF53098 2 210 4.23E-67 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 TIGRFAM TIGR01388 rnd: ribonuclease D 5 372 8.9E-157 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 Pfam PF00570 HRDC domain 213 279 2.0E-14 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 SUPERFAMILY SSF47819 295 372 3.18E-23 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 Hamap MF_01899 Ribonuclease D [rnd]. 3 371 45.255 T 28-03-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 SUPERFAMILY SSF47819 195 301 6.21E-30 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 Pfam PF01612 3'-5' exonuclease 3 170 5.3E-46 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 Gene3D G3DSA:3.30.420.10 1 194 7.2E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 SMART SM00474 3 171 2.0E-54 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM46_RS05025 6931b1f5974ec184c98627197035e273 375 Gene3D G3DSA:1.10.150.80 195 293 9.0E-23 T 28-03-2018 WM46_RS08785 f4bb6698616aa7277896b26c37a9e2cf 134 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site WM46_RS08785 f4bb6698616aa7277896b26c37a9e2cf 134 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 134 2.4E-51 T 28-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 WM46_RS08785 f4bb6698616aa7277896b26c37a9e2cf 134 Pfam PF00460 Flagella basal body rod protein 7 37 1.3E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 WM46_RS08785 f4bb6698616aa7277896b26c37a9e2cf 134 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 87 131 2.4E-12 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 Hamap MF_00174 Elongation factor P--(R)-beta-lysine ligase [epmA]. 2 325 57.815 T 28-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 SUPERFAMILY SSF55681 12 320 3.98E-85 T 28-03-2018 WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 Pfam PF00152 tRNA synthetases class II (D, K and N) 15 321 1.1E-49 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 17 320 2.0E-133 T 28-03-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 PRINTS PR00982 Lysyl-tRNA synthetase signature 99 116 2.5E-6 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 PRINTS PR00982 Lysyl-tRNA synthetase signature 31 41 2.5E-6 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS22815 6c22502b339a8aeb747cfeace4cd6e51 325 Gene3D G3DSA:3.30.930.10 9 324 2.9E-70 T 28-03-2018 WM46_RS13740 bb9903e710efdcd347fc22ca642cdc46 242 Gene3D G3DSA:3.30.420.10 1 191 4.8E-41 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13740 bb9903e710efdcd347fc22ca642cdc46 242 SUPERFAMILY SSF53098 7 183 6.51E-53 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13740 bb9903e710efdcd347fc22ca642cdc46 242 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 7 241 5.7E-96 T 28-03-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS13740 bb9903e710efdcd347fc22ca642cdc46 242 Pfam PF00929 Exonuclease 9 175 4.9E-42 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS13740 bb9903e710efdcd347fc22ca642cdc46 242 SMART SM00479 7 184 4.6E-52 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS13740 bb9903e710efdcd347fc22ca642cdc46 242 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 6 224 2.9E-97 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 SUPERFAMILY SSF54373 180 283 1.84E-24 T 28-03-2018 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 Pfam PF01494 FAD binding domain 6 184 6.8E-11 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 9.1E-6 T 28-03-2018 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 9.1E-6 T 28-03-2018 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 SUPERFAMILY SSF51905 2 179 4.45E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 SUPERFAMILY SSF51905 283 392 4.45E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS07940 d725a5c7be74a046e5f8974936dba400 429 Gene3D G3DSA:3.50.50.60 1 364 1.0E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02375 59313af30f29aceada0b7710f1787826 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02375 59313af30f29aceada0b7710f1787826 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02375 59313af30f29aceada0b7710f1787826 312 Gene3D G3DSA:3.40.1190.20 47 312 1.8E-54 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02375 59313af30f29aceada0b7710f1787826 312 SUPERFAMILY SSF53613 7 290 2.81E-69 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02375 59313af30f29aceada0b7710f1787826 312 PIRSF PIRSF000535 2 311 2.6E-118 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 WM46_RS02375 59313af30f29aceada0b7710f1787826 312 Gene3D G3DSA:2.20.150.10 12 46 8.7E-11 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain WM46_RS02375 59313af30f29aceada0b7710f1787826 312 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 5 308 4.2E-99 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 WM46_RS02375 59313af30f29aceada0b7710f1787826 312 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 5 308 2.0E-101 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 WM46_RS02375 59313af30f29aceada0b7710f1787826 312 Pfam PF00294 pfkB family carbohydrate kinase 14 293 3.5E-68 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS25155 cf7080a10af6e86707020218474c2339 492 SUPERFAMILY SSF53067 218 467 1.3E-44 T 28-03-2018 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 Gene3D G3DSA:3.30.420.40 115 213 6.8E-17 T 28-03-2018 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 PIRSF PIRSF000538 112 472 2.6E-52 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 PIRSF PIRSF000538 3 117 4.7E-17 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 225 418 1.2E-22 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 SUPERFAMILY SSF53067 4 216 1.69E-38 T 28-03-2018 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 Gene3D G3DSA:3.30.420.40 214 468 3.8E-45 T 28-03-2018 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 121 216 1.5E-7 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 110 1.6E-11 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS25155 cf7080a10af6e86707020218474c2339 492 Gene3D G3DSA:3.30.420.40 1 114 5.1E-21 T 28-03-2018 WM46_RS20025 bd45b0c792bb7687748990a12c184c0a 460 Gene3D G3DSA:1.20.1250.20 19 217 6.8E-14 T 28-03-2018 WM46_RS20025 bd45b0c792bb7687748990a12c184c0a 460 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 444 6.5E-152 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS20025 bd45b0c792bb7687748990a12c184c0a 460 SUPERFAMILY SSF103473 13 426 1.96E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20025 bd45b0c792bb7687748990a12c184c0a 460 Pfam PF13347 MFS/sugar transport protein 13 429 3.7E-101 T 28-03-2018 WM46_RS20025 bd45b0c792bb7687748990a12c184c0a 460 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 62 87 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 WM46_RS20025 bd45b0c792bb7687748990a12c184c0a 460 Gene3D G3DSA:1.20.1250.20 218 431 9.7E-10 T 28-03-2018 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 1 627 0.0 T 28-03-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Gene3D G3DSA:3.40.50.980 240 398 1.0E-33 T 28-03-2018 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 SUPERFAMILY SSF56801 4 625 7.46E-156 T 28-03-2018 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Pfam PF00501 AMP-binding enzyme 59 500 5.2E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Gene3D G3DSA:3.40.50.980 49 239 8.5E-41 T 28-03-2018 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 592 1.8E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 57 7.4E-22 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Gene3D G3DSA:2.30.38.10 399 493 1.1E-10 T 28-03-2018 WM46_RS13160 04667cbc86a045e54d3339a6be33f077 628 Gene3D G3DSA:3.30.300.30 494 608 1.4E-22 T 28-03-2018 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 SUPERFAMILY SSF50129 8 174 4.41E-50 T 28-03-2018 IPR011032 GroES-like WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 SMART SM00829 12 344 0.0011 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 146 3.0E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 Gene3D G3DSA:3.40.50.20 255 344 2.5E-5 T 28-03-2018 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 Gene3D G3DSA:3.40.50.20 193 254 2.0E-17 T 28-03-2018 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 SUPERFAMILY SSF51735 150 314 4.04E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 180 207 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 Pfam PF00107 Zinc-binding dehydrogenase 187 310 9.3E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS13240 2c33c936371628a08fbf8b905af3db1b 351 Gene3D G3DSA:3.90.180.10 7 192 9.3E-54 T 28-03-2018 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 Pfam PF02311 AraC-like ligand binding domain 15 153 2.3E-25 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 Gene3D G3DSA:2.60.120.280 3 159 1.9E-18 T 28-03-2018 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 Gene3D G3DSA:1.10.10.60 226 274 1.8E-9 T 28-03-2018 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 Pfam PF12833 Helix-turn-helix domain 193 270 9.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 SUPERFAMILY SSF46689 174 221 5.38E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 SUPERFAMILY SSF51215 13 153 1.07E-25 T 28-03-2018 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 SUPERFAMILY SSF46689 223 272 2.02E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 Gene3D G3DSA:1.10.10.60 166 225 1.3E-11 T 28-03-2018 WM46_RS22680 f9f620fa2f36729f1df97cd35ef75a3b 281 SMART SM00342 187 269 1.0E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS08265 6fe7165f5138efbc8e5f32df2309855f 293 Gene3D G3DSA:1.10.10.10 5 109 1.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08265 6fe7165f5138efbc8e5f32df2309855f 293 SUPERFAMILY SSF53697 101 286 1.57E-37 T 28-03-2018 WM46_RS08265 6fe7165f5138efbc8e5f32df2309855f 293 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 79 7.0E-18 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS08265 6fe7165f5138efbc8e5f32df2309855f 293 SUPERFAMILY SSF46689 7 81 3.58E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS08265 6fe7165f5138efbc8e5f32df2309855f 293 Gene3D G3DSA:3.40.50.10490 110 286 1.9E-34 T 28-03-2018 WM46_RS08265 6fe7165f5138efbc8e5f32df2309855f 293 Pfam PF01380 SIS domain 133 259 1.4E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS21665 f633a6af6c20de204f6535ba03592d02 175 Pfam PF00436 Single-strand binding protein family 6 112 1.8E-42 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 WM46_RS21665 f633a6af6c20de204f6535ba03592d02 175 Gene3D G3DSA:2.40.50.140 1 118 2.0E-46 T 28-03-2018 WM46_RS21665 f633a6af6c20de204f6535ba03592d02 175 SUPERFAMILY SSF50249 4 175 8.23E-63 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS21665 f633a6af6c20de204f6535ba03592d02 175 PIRSF PIRSF002070 2 158 1.7E-41 T 28-03-2018 WM46_RS21665 f633a6af6c20de204f6535ba03592d02 175 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 175 1.8E-63 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM46_RS21665 f633a6af6c20de204f6535ba03592d02 175 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 39.824 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 Pfam PF01926 50S ribosome-binding GTPase 161 284 1.9E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 Hamap MF_01454 GTPase Obg [obg]. 2 333 48.265 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 331 3.0E-148 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 SUPERFAMILY SSF52540 151 344 2.96E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 Gene3D G3DSA:3.40.50.300 159 378 7.2E-33 T 28-03-2018 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 SUPERFAMILY SSF82051 2 157 1.24E-56 T 28-03-2018 IPR006169 GTP1/OBG domain WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 Pfam PF01018 GTP1/OBG 4 157 1.0E-58 T 28-03-2018 IPR006169 GTP1/OBG domain WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 3.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 3.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 3.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 3.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 Gene3D G3DSA:2.70.210.12 2 156 7.4E-58 T 28-03-2018 IPR006169 GTP1/OBG domain WM46_RS16840 8688639edc5bee7c2e55c26b21cf8eae 390 PIRSF PIRSF002401 1 376 4.8E-141 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 ProSitePatterns PS00928 Trehalase signature 2. 459 468 - T 28-03-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 452 468 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 314 331 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 346 363 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 530 543 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 207 225 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 281 298 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 PRINTS PR00744 Glycosyl hydrolase family 37 signature 389 405 9.2E-46 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 Pfam PF01204 Trehalase 70 546 3.6E-163 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 Hamap MF_01059 Cytoplasmic trehalase [treF]. 34 549 80.317 T 28-03-2018 IPR023715 Trehalase, cytoplasmic GO:0004555|GO:0005737|GO:0005993|GO:0071474 KEGG: 00500+3.2.1.28 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 SUPERFAMILY SSF48208 55 547 4.42E-147 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 Gene3D G3DSA:1.50.10.10 56 549 4.2E-136 T 28-03-2018 WM46_RS20755 060d2671dcdbedf694d6f9ee14253b31 549 ProSitePatterns PS00927 Trehalase signature 1. 165 178 - T 28-03-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 550 53.957 T 28-03-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 SUPERFAMILY SSF50715 340 548 1.15E-79 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Gene3D G3DSA:1.10.1160.10 261 338 2.2E-36 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Gene3D G3DSA:2.40.240.10 463 548 2.2E-32 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 552 0.0 T 28-03-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 2.4E-9 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 2.4E-9 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 2.4E-9 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 2.4E-9 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Gene3D G3DSA:3.40.50.620 7 41 0.14 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Gene3D G3DSA:3.40.50.620 155 260 2.1E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Gene3D G3DSA:3.40.50.620 42 154 2.9E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 1.1E-126 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 SUPERFAMILY SSF52374 11 337 4.56E-103 T 28-03-2018 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Gene3D G3DSA:2.40.240.10 348 462 1.3E-47 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS11205 9d1d6ee61c9a7713fee212fbab374355 555 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 529 9.4E-64 T 28-03-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS13680 519a5c1a8c3841a3aa2e0f6d7ac904d7 150 Pfam PF13673 Acetyltransferase (GNAT) domain 31 145 1.3E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS13680 519a5c1a8c3841a3aa2e0f6d7ac904d7 150 Gene3D G3DSA:3.40.630.30 1 85 6.0E-15 T 28-03-2018 WM46_RS13680 519a5c1a8c3841a3aa2e0f6d7ac904d7 150 Gene3D G3DSA:3.40.630.30 86 150 6.3E-7 T 28-03-2018 WM46_RS13680 519a5c1a8c3841a3aa2e0f6d7ac904d7 150 SUPERFAMILY SSF55729 3 146 3.01E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Pfam PF14579 Helix-hairpin-helix motif 808 897 3.3E-25 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Gene3D G3DSA:1.10.150.280 780 894 3.6E-8 T 28-03-2018 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Gene3D G3DSA:3.20.20.140 1 247 3.8E-39 T 28-03-2018 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 SMART SM00481 7 74 1.0E-25 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1031 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 292 735 2.1E-177 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Pfam PF02811 PHP domain 8 171 1.4E-39 T 28-03-2018 IPR004013 PHP domain GO:0003824 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Gene3D G3DSA:2.40.50.140 979 1074 4.9E-16 T 28-03-2018 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 SUPERFAMILY SSF89550 6 263 1.77E-16 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM46_RS13900 c414c5d220b907e598eab6143e85d47b 1160 Pfam PF01336 OB-fold nucleic acid binding domain 1000 1072 1.8E-8 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM46_RS08610 427bb9585c7b35ec60c6030f3b448e37 341 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 11 318 1.8E-99 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS08610 427bb9585c7b35ec60c6030f3b448e37 341 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 332 48.507 T 28-03-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 WM46_RS08610 427bb9585c7b35ec60c6030f3b448e37 341 Gene3D G3DSA:3.20.20.300 1 341 1.0E-80 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS08610 427bb9585c7b35ec60c6030f3b448e37 341 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 234 251 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 WM46_RS08610 427bb9585c7b35ec60c6030f3b448e37 341 SUPERFAMILY SSF51445 3 318 2.0E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Gene3D G3DSA:2.30.42.10 367 455 8.6E-15 T 28-03-2018 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 SUPERFAMILY SSF50156 384 454 5.13E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Gene3D G3DSA:2.30.42.10 262 366 1.1E-25 T 28-03-2018 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Gene3D G3DSA:2.40.10.10 140 257 2.0E-40 T 28-03-2018 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 PRINTS PR00834 HtrA/DegQ protease family signature 221 238 4.0E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 PRINTS PR00834 HtrA/DegQ protease family signature 307 319 4.0E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 PRINTS PR00834 HtrA/DegQ protease family signature 199 216 4.0E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 PRINTS PR00834 HtrA/DegQ protease family signature 102 114 4.0E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 PRINTS PR00834 HtrA/DegQ protease family signature 123 143 4.0E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 PRINTS PR00834 HtrA/DegQ protease family signature 164 188 4.0E-58 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 376 443 5.5E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Pfam PF13365 Trypsin-like peptidase domain 92 228 1.0E-29 T 28-03-2018 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Gene3D G3DSA:2.40.10.10 31 139 5.4E-34 T 28-03-2018 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 Pfam PF13180 PDZ domain 278 358 4.7E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 SUPERFAMILY SSF50494 39 263 3.29E-62 T 28-03-2018 IPR009003 Peptidase S1, PA clan WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 41 453 1.7E-160 T 28-03-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 SUPERFAMILY SSF50156 225 350 6.57E-23 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 SMART SM00228 267 349 1.8E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17070 afd3d87734786da4803ad36a86c223ff 455 SMART SM00228 374 447 1.5E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 1.8E-27 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 SUPERFAMILY SSF48179 191 287 1.67E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Gene3D G3DSA:3.40.50.720 288 388 8.1E-17 T 28-03-2018 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 376 4.6E-8 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 PIRSF PIRSF000124 1 388 1.7E-140 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Gene3D G3DSA:1.10.1040.10 212 287 6.2E-28 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 SUPERFAMILY SSF52413 283 387 2.49E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 PIRSF PIRSF500134 338 388 6.2E-4 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 PIRSF PIRSF500134 1 344 1.9E-119 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 169 3.3E-31 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Gene3D G3DSA:3.40.50.720 1 193 1.6E-48 T 28-03-2018 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 378 9.7E-103 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 SUPERFAMILY SSF51735 1 194 1.17E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 SMART SM00984 300 387 1.8E-12 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS02995 2064da35b1566df71cb8dd2d317e3c4e 388 Gene3D G3DSA:1.20.5.100 194 211 4.9E-14 T 28-03-2018 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 Gene3D G3DSA:3.40.50.2300 1 135 1.0E-23 T 28-03-2018 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 SMART SM00448 1 112 8.6E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 SMART SM00850 145 243 1.3E-38 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 Pfam PF00072 Response regulator receiver domain 3 112 9.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 Gene3D G3DSA:2.40.50.40 136 205 2.1E-17 T 28-03-2018 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 SUPERFAMILY SSF52172 2 164 7.83E-27 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 Pfam PF04397 LytTr DNA-binding domain 146 242 7.2E-33 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM46_RS01340 28232faefd29b09cb72cb47808123c48 244 Gene3D G3DSA:2.20.25.10 206 243 6.3E-18 T 28-03-2018 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 10 477 3.1E-237 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 Gene3D G3DSA:3.40.309.10 268 465 1.5E-67 T 28-03-2018 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 SUPERFAMILY SSF53720 4 483 6.54E-169 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 Gene3D G3DSA:3.40.605.10 1 267 2.5E-105 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 Hamap MF_00804 NAD/NADP-dependent betaine aldehyde dehydrogenase [betB]. 4 490 57.905 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 WM46_RS11720 89dde708ed746f5eece926ac4055403b 490 Pfam PF00171 Aldehyde dehydrogenase family 17 479 1.2E-175 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS04465 cbea6536189e1ff03339d492218ff87d 164 SUPERFAMILY SSF54171 106 159 2.75E-6 T 28-03-2018 IPR016177 DNA-binding domain GO:0003677 WM46_RS04465 cbea6536189e1ff03339d492218ff87d 164 Pfam PF00847 AP2 domain 106 143 3.3E-6 T 28-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 WM46_RS04465 cbea6536189e1ff03339d492218ff87d 164 Pfam PF13392 HNH endonuclease 53 95 7.1E-14 T 28-03-2018 IPR003615 HNH nuclease WM46_RS04465 cbea6536189e1ff03339d492218ff87d 164 SUPERFAMILY SSF54060 16 101 2.0E-20 T 28-03-2018 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 3.7E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 Gene3D G3DSA:3.40.190.10 95 181 1.1E-9 T 28-03-2018 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 SUPERFAMILY SSF46785 5 115 1.26E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 SUPERFAMILY SSF53850 94 302 3.62E-39 T 28-03-2018 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 Gene3D G3DSA:1.10.10.10 2 93 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 Gene3D G3DSA:3.40.190.10 182 270 4.0E-22 T 28-03-2018 WM46_RS08730 6771ea97da694664cad1d5067d21f171 311 Pfam PF03466 LysR substrate binding domain 94 298 7.1E-37 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 Gene3D G3DSA:1.20.1250.20 246 462 4.2E-19 T 28-03-2018 WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 PIRSF PIRSF002808 11 461 1.6E-102 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 SUPERFAMILY SSF103473 20 450 1.57E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 426 6.0E-148 T 28-03-2018 WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 ProSitePatterns PS00942 glpT family of transporters signature. 156 172 - T 28-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 Pfam PF07690 Major Facilitator Superfamily 35 397 2.0E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19850 14bdb7310d895e13f9f11e66273f336e 463 Gene3D G3DSA:1.20.1250.20 16 244 4.6E-23 T 28-03-2018 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 14 421 2.1E-242 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 Gene3D G3DSA:1.10.580.10 27 281 7.9E-87 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PRINTS PR00143 Citrate synthase signature 165 178 5.1E-56 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PRINTS PR00143 Citrate synthase signature 359 375 5.1E-56 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PRINTS PR00143 Citrate synthase signature 219 234 5.1E-56 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PRINTS PR00143 Citrate synthase signature 241 269 5.1E-56 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PRINTS PR00143 Citrate synthase signature 379 393 5.1E-56 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PRINTS PR00143 Citrate synthase signature 296 316 5.1E-56 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 SUPERFAMILY SSF48256 8 422 1.09E-167 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 Gene3D G3DSA:1.10.230.10 282 379 4.8E-37 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 PIRSF PIRSF001369 38 427 8.5E-176 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 Pfam PF00285 Citrate synthase, C-terminal domain 46 410 1.4E-131 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS11020 59c57e876fa31ef4f2eb7c5c45061dfa 427 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 280 3.2E-121 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 24 65 1.6E-7 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 Pfam PF02569 Pantoate-beta-alanine ligase 3 278 2.3E-101 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 39.435 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 SUPERFAMILY SSF52374 3 280 2.31E-104 T 28-03-2018 WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 Gene3D G3DSA:3.40.50.620 1 176 3.5E-75 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14115 369888ec349ff1f4aca7d585134e209b 284 Gene3D G3DSA:3.30.1300.10 180 283 1.9E-30 T 28-03-2018 WM46_RS13910 f98cfd3de5f546273b96f3cd611a84aa 382 Gene3D G3DSA:3.40.50.2000 185 367 6.8E-15 T 28-03-2018 WM46_RS13910 f98cfd3de5f546273b96f3cd611a84aa 382 Pfam PF02684 Lipid-A-disaccharide synthetase 9 377 2.3E-156 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS13910 f98cfd3de5f546273b96f3cd611a84aa 382 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 1 380 4.5E-189 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS13910 f98cfd3de5f546273b96f3cd611a84aa 382 SUPERFAMILY SSF53756 9 376 2.98E-28 T 28-03-2018 WM46_RS13910 f98cfd3de5f546273b96f3cd611a84aa 382 Gene3D G3DSA:3.40.50.2000 1 184 6.8E-5 T 28-03-2018 WM46_RS13910 f98cfd3de5f546273b96f3cd611a84aa 382 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 6 382 43.593 T 28-03-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS21180 48e43a0e8f6ead1a329914d0295644dd 165 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 26.485 T 28-03-2018 IPR022973 Ribosomal protein L10 WM46_RS21180 48e43a0e8f6ead1a329914d0295644dd 165 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS21180 48e43a0e8f6ead1a329914d0295644dd 165 Pfam PF00466 Ribosomal protein L10 5 101 4.1E-25 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 WM46_RS21180 48e43a0e8f6ead1a329914d0295644dd 165 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 78 161 1.0E-4 T 28-03-2018 WM46_RS21180 48e43a0e8f6ead1a329914d0295644dd 165 SUPERFAMILY SSF160369 4 160 2.35E-47 T 28-03-2018 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 Gene3D G3DSA:3.30.499.10 31 239 2.2E-74 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 Gene3D G3DSA:3.30.499.10 372 576 6.0E-62 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 Gene3D G3DSA:3.20.19.10 652 891 1.6E-94 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 ProSitePatterns PS00450 Aconitase family signature 1. 427 443 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 890 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 ProSitePatterns PS01244 Aconitase family signature 2. 493 506 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 217 232 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 431 442 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 279 292 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 293 306 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 146 159 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 203 216 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 493 506 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 170 178 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 PRINTS PR00415 Aconitase family signature 372 386 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 SUPERFAMILY SSF52016 630 890 5.49E-91 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 Gene3D G3DSA:3.40.1060.10 240 371 1.4E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 Pfam PF00330 Aconitase family (aconitate hydratase) 69 562 2.7E-181 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 Pfam PF00694 Aconitase C-terminal domain 691 818 3.1E-51 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS05915 0d1bbc1a62109e897a191c1aac737a70 891 SUPERFAMILY SSF53732 10 625 2.62E-223 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 Gene3D G3DSA:3.40.50.880 9 241 3.9E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 SUPERFAMILY SSF46689 223 273 4.61E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 Gene3D G3DSA:1.10.10.60 278 327 6.1E-12 T 28-03-2018 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 SUPERFAMILY SSF46689 276 326 1.48E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 SUPERFAMILY SSF52317 16 204 1.09E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 Gene3D G3DSA:1.10.260.40 254 277 0.035 T 28-03-2018 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 Pfam PF12833 Helix-turn-helix domain 245 323 1.6E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 Gene3D G3DSA:1.10.10.60 242 253 0.038 T 28-03-2018 WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 Pfam PF01965 DJ-1/PfpI family 16 183 2.9E-18 T 28-03-2018 IPR002818 DJ-1/PfpI WM46_RS07135 ef04d7e2301da5dc1949c763875e4d93 330 SMART SM00342 239 322 6.7E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS14640 5d53cb519be2dfb2fb60315712bf4743 405 Hamap MF_01050 L-carnitine CoA-transferase [caiB]. 1 405 96.479 T 28-03-2018 IPR023452 L-carnitine CoA-transferase CaiB GO:0009437|GO:0016782 WM46_RS14640 5d53cb519be2dfb2fb60315712bf4743 405 SUPERFAMILY SSF89796 5 401 1.7E-99 T 28-03-2018 IPR023606 CoA-transferase family III domain WM46_RS14640 5d53cb519be2dfb2fb60315712bf4743 405 Pfam PF02515 CoA-transferase family III 12 378 1.0E-78 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 WM46_RS14640 5d53cb519be2dfb2fb60315712bf4743 405 Gene3D G3DSA:3.40.50.10540 6 405 1.1E-82 T 28-03-2018 IPR023606 CoA-transferase family III domain WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 TIGRFAM TIGR02183 GRXA: glutaredoxin, GrxA family 2 86 3.7E-52 T 28-03-2018 IPR011902 Glutaredoxin, GrxA GO:0009055|GO:0015035|GO:0045454 WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 ProSitePatterns PS00195 Glutaredoxin active site. 5 20 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 Pfam PF00462 Glutaredoxin 4 69 6.7E-17 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 SUPERFAMILY SSF52833 4 82 7.12E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 PRINTS PR00160 Glutaredoxin signature 3 21 6.0E-12 T 28-03-2018 IPR014025 Glutaredoxin subgroup WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 PRINTS PR00160 Glutaredoxin signature 66 79 6.0E-12 T 28-03-2018 IPR014025 Glutaredoxin subgroup WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 PRINTS PR00160 Glutaredoxin signature 52 65 6.0E-12 T 28-03-2018 IPR014025 Glutaredoxin subgroup WM46_RS10185 bb9c5f787cb2e10386a11ae76a3a248a 87 Gene3D G3DSA:3.40.30.10 1 84 3.4E-22 T 28-03-2018 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 SMART SM00841 131 186 6.9E-33 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Gene3D G3DSA:2.30.30.30 4 63 3.2E-24 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Hamap MF_00141 Elongation factor P [efp]. 3 187 50.541 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 TIGRFAM TIGR00038 efp: translation elongation factor P 6 187 5.8E-76 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 7 61 1.4E-23 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 SUPERFAMILY SSF50249 70 128 4.24E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 SMART SM01185 69 123 5.3E-25 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 PIRSF PIRSF005901 2 188 1.4E-66 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 SUPERFAMILY SSF50249 130 187 1.2E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 72 123 7.5E-22 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Gene3D G3DSA:2.40.50.140 67 129 4.8E-24 T 28-03-2018 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 SUPERFAMILY SSF50104 3 63 2.35E-17 T 28-03-2018 IPR008991 Translation protein SH3-like domain WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Pfam PF09285 Elongation factor P, C-terminal 131 186 4.3E-26 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 WM46_RS22760 e2fce45e53b6e16b846f9f0e0d498f2a 188 Gene3D G3DSA:2.40.50.140 131 186 1.4E-27 T 28-03-2018 WM46_RS10190 141e4adb4327cd7f135bd4e6d3f5355b 125 Pfam PF11045 Putative inner membrane protein of Enterobacteriaceae 4 117 2.5E-45 T 28-03-2018 IPR020368 Uncharacterised protein family YbjM GO:0016021 WM46_RS10190 141e4adb4327cd7f135bd4e6d3f5355b 125 ProDom PD079046 MEMBRANE INNER YBJM TRANSMEMBRANE 1 117 2.0E-36 T 28-03-2018 IPR020368 Uncharacterised protein family YbjM GO:0016021 WM46_RS04820 6c2803cb7f0daa8159da03caa9b2e5ed 83 Gene3D G3DSA:2.10.109.10 2 82 2.4E-11 T 28-03-2018 WM46_RS04820 6c2803cb7f0daa8159da03caa9b2e5ed 83 SUPERFAMILY SSF51306 1 78 5.76E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS02385 f9c2004c0102dce20355b463de4f3cfc 313 Gene3D G3DSA:3.40.1190.20 2 312 7.2E-54 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02385 f9c2004c0102dce20355b463de4f3cfc 313 SUPERFAMILY SSF53613 7 305 7.17E-59 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02385 f9c2004c0102dce20355b463de4f3cfc 313 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 40 64 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02385 f9c2004c0102dce20355b463de4f3cfc 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02385 f9c2004c0102dce20355b463de4f3cfc 313 Pfam PF00294 pfkB family carbohydrate kinase 5 295 1.4E-60 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS20255 1b60075f37e8157f169dd73a2c721a22 319 Gene3D G3DSA:3.20.20.370 17 241 2.9E-80 T 28-03-2018 WM46_RS20255 1b60075f37e8157f169dd73a2c721a22 319 Pfam PF04748 Divergent polysaccharide deacetylase 28 238 1.0E-74 T 28-03-2018 IPR006837 Divergent polysaccharide deacetylase WM46_RS20255 1b60075f37e8157f169dd73a2c721a22 319 SUPERFAMILY SSF88713 24 238 3.39E-72 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS15895 79efbac7e8784716f2b24f313c419048 289 SUPERFAMILY SSF47616 133 279 1.02E-32 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS15895 79efbac7e8784716f2b24f313c419048 289 Gene3D G3DSA:3.40.30.10 45 145 3.4E-23 T 28-03-2018 WM46_RS15895 79efbac7e8784716f2b24f313c419048 289 Pfam PF02798 Glutathione S-transferase, N-terminal domain 45 127 2.3E-5 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS15895 79efbac7e8784716f2b24f313c419048 289 SUPERFAMILY SSF52833 37 130 6.34E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS15895 79efbac7e8784716f2b24f313c419048 289 Gene3D G3DSA:1.20.1050.10 146 288 6.5E-28 T 28-03-2018 WM46_RS15895 79efbac7e8784716f2b24f313c419048 289 Pfam PF13410 Glutathione S-transferase, C-terminal domain 174 244 3.3E-9 T 28-03-2018 WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 Gene3D G3DSA:3.40.50.2300 167 340 4.9E-33 T 28-03-2018 WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 Gene3D G3DSA:1.10.260.40 3 61 1.4E-10 T 28-03-2018 WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 SUPERFAMILY SSF53822 72 339 1.53E-37 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 1.2E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 Pfam PF13377 Periplasmic binding protein-like domain 174 337 1.2E-26 T 28-03-2018 WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 SUPERFAMILY SSF47413 4 59 1.51E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS10330 fe11e80074711cc01b32985ea3dd01d0 357 Gene3D G3DSA:3.40.50.2300 62 166 2.0E-8 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 58 82 6.4E-11 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 84 104 6.4E-11 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 417 439 6.4E-11 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 265 287 6.4E-11 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 Pfam PF00361 Proton-conducting membrane transporter 133 425 7.2E-99 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 610 1.4E-237 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 247 273 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 246 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 418 437 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 82 107 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 315 327 9.5E-55 T 28-03-2018 WM46_RS01810 194cba2485c22409d49cfe0a17ee7aba 613 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 121 7.3E-23 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS13325 a2198aaa881e942cd96505fdd91d074f 444 SUPERFAMILY SSF52777 18 193 7.89E-29 T 28-03-2018 WM46_RS13325 a2198aaa881e942cd96505fdd91d074f 444 Pfam PF00668 Condensation domain 16 353 1.2E-42 T 28-03-2018 IPR001242 Condensation domain WM46_RS13325 a2198aaa881e942cd96505fdd91d074f 444 Gene3D G3DSA:3.30.559.10 5 234 1.1E-20 T 28-03-2018 WM46_RS13325 a2198aaa881e942cd96505fdd91d074f 444 SUPERFAMILY SSF52777 200 435 3.39E-24 T 28-03-2018 WM46_RS00235 ab700d6a8600645d3cde7bde5e555cc0 356 Gene3D G3DSA:3.20.20.70 9 356 2.3E-130 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS00235 ab700d6a8600645d3cde7bde5e555cc0 356 PIRSF PIRSF001361 1 354 1.8E-164 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM46_RS00235 ab700d6a8600645d3cde7bde5e555cc0 356 SUPERFAMILY SSF51569 8 345 3.02E-135 T 28-03-2018 WM46_RS00235 ab700d6a8600645d3cde7bde5e555cc0 356 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 8 350 5.4E-175 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM46_RS00235 ab700d6a8600645d3cde7bde5e555cc0 356 Pfam PF00793 DAHP synthetase I family 40 340 1.3E-108 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS07505 69d740c2f0d067b046b5732cc7b721fa 155 Pfam PF05433 Glycine zipper 2TM domain 62 102 2.4E-7 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 WM46_RS05970 a493b301d767f8422c490450363d6294 644 Hamap MF_01036 Exoribonuclease 2 [rnb]. 1 643 45.272 T 28-03-2018 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 WM46_RS05970 a493b301d767f8422c490450363d6294 644 SUPERFAMILY SSF50249 176 556 4.2E-115 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS05970 a493b301d767f8422c490450363d6294 644 SUPERFAMILY SSF50249 8 80 1.08E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS05970 a493b301d767f8422c490450363d6294 644 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 6 641 1.3E-247 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 WM46_RS05970 a493b301d767f8422c490450363d6294 644 SMART SM00357 23 79 1.0E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS05970 a493b301d767f8422c490450363d6294 644 Pfam PF00575 S1 RNA binding domain 559 636 2.0E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS05970 a493b301d767f8422c490450363d6294 644 ProSitePatterns PS01175 Ribonuclease II family signature. 484 508 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site WM46_RS05970 a493b301d767f8422c490450363d6294 644 Pfam PF00773 RNB domain 189 516 7.4E-85 T 28-03-2018 WM46_RS05970 a493b301d767f8422c490450363d6294 644 Gene3D G3DSA:2.40.50.140 558 644 1.2E-7 T 28-03-2018 WM46_RS05970 a493b301d767f8422c490450363d6294 644 SUPERFAMILY SSF50249 560 642 1.77E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS05970 a493b301d767f8422c490450363d6294 644 Pfam PF08206 Ribonuclease B OB domain 24 80 1.3E-19 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain WM46_RS05970 a493b301d767f8422c490450363d6294 644 SUPERFAMILY SSF50249 83 171 3.26E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS05970 a493b301d767f8422c490450363d6294 644 TIGRFAM TIGR02062 RNase_B: exoribonuclease II 1 642 0.0 T 28-03-2018 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 WM46_RS05970 a493b301d767f8422c490450363d6294 644 SMART SM00955 189 517 9.1E-130 T 28-03-2018 WM46_RS16055 7465cef3d0f40220c0d6633d2c5a4f31 130 Gene3D G3DSA:2.40.50.200 22 130 3.9E-41 T 28-03-2018 WM46_RS16055 7465cef3d0f40220c0d6633d2c5a4f31 130 TIGRFAM TIGR00156 TIGR00156: TIGR00156 family protein 2 128 2.1E-62 T 28-03-2018 IPR016052 Bacteriophage 933W, L0136 WM46_RS16055 7465cef3d0f40220c0d6633d2c5a4f31 130 SUPERFAMILY SSF101756 31 127 2.62E-36 T 28-03-2018 IPR005220 Bacterial OB-fold WM46_RS16055 7465cef3d0f40220c0d6633d2c5a4f31 130 Pfam PF04076 Bacterial OB fold (BOF) protein 25 127 4.6E-46 T 28-03-2018 IPR005220 Bacterial OB-fold WM46_RS20345 4d1d65aa3b2a3cd22cfaeb1fd7214d1a 120 PIRSF PIRSF028770 1 120 3.1E-62 T 28-03-2018 IPR011223 Uncharacterised conserved protein UCP028770 WM46_RS20345 4d1d65aa3b2a3cd22cfaeb1fd7214d1a 120 Pfam PF11742 Protein of unknown function (DUF3302) 3 78 4.3E-40 T 28-03-2018 IPR011223 Uncharacterised conserved protein UCP028770 WM46_RS00715 1044585452c2be5a5f8753f0adfe9d66 206 Gene3D G3DSA:1.25.40.10 3 195 7.7E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00715 1044585452c2be5a5f8753f0adfe9d66 206 Pfam PF09976 Tetratricopeptide repeat-like domain 15 205 7.2E-55 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 WM46_RS00715 1044585452c2be5a5f8753f0adfe9d66 206 PIRSF PIRSF006170 1 206 8.9E-57 T 28-03-2018 IPR026039 Uncharacterised protein family UPF0070 WM46_RS00715 1044585452c2be5a5f8753f0adfe9d66 206 SUPERFAMILY SSF48452 88 186 4.98E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS11780 44f63fefb248914665a4409462547680 323 Gene3D G3DSA:3.40.50.2300 165 323 1.3E-46 T 28-03-2018 WM46_RS11780 44f63fefb248914665a4409462547680 323 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS11780 44f63fefb248914665a4409462547680 323 Gene3D G3DSA:3.40.50.2300 57 164 7.7E-20 T 28-03-2018 WM46_RS11780 44f63fefb248914665a4409462547680 323 SUPERFAMILY SSF53822 60 323 2.86E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS11780 44f63fefb248914665a4409462547680 323 Pfam PF13377 Periplasmic binding protein-like domain 166 323 3.1E-35 T 28-03-2018 WM46_RS11780 44f63fefb248914665a4409462547680 323 SMART SM00354 1 70 3.8E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS11780 44f63fefb248914665a4409462547680 323 SUPERFAMILY SSF47413 2 58 3.38E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS11780 44f63fefb248914665a4409462547680 323 Gene3D G3DSA:1.10.260.40 1 56 7.6E-23 T 28-03-2018 WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 SUPERFAMILY SSF54631 291 431 2.36E-25 T 28-03-2018 WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 Pfam PF03741 Integral membrane protein TerC family 14 203 1.3E-49 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 Pfam PF00571 CBS domain 302 358 1.1E-4 T 28-03-2018 IPR000644 CBS domain WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 Pfam PF00571 CBS domain 372 422 1.0E-6 T 28-03-2018 IPR000644 CBS domain WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 Pfam PF03471 Transporter associated domain 440 516 7.4E-20 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 SMART SM01091 439 518 6.0E-26 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 Gene3D G3DSA:3.30.465.10 434 518 1.8E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 SUPERFAMILY SSF56176 437 522 8.45E-22 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS02780 33994e80da3546fefb1322cb4019bf87 527 Gene3D G3DSA:3.10.580.10 283 433 5.8E-27 T 28-03-2018 WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 7.1E-267 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 SUPERFAMILY SSF52540 3 269 2.23E-122 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 Pfam PF00117 Glutamine amidotransferase class-I 301 535 1.3E-65 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 Pfam PF06418 CTP synthase N-terminus 5 266 3.9E-126 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 Hamap MF_01227 CTP synthase [pyrG]. 3 540 51.533 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 SUPERFAMILY SSF52317 289 542 5.59E-89 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 Gene3D G3DSA:3.40.50.300 1 285 4.9E-129 T 28-03-2018 WM46_RS25125 4343f1b58db927f88f7f485c59ce91cf 545 Gene3D G3DSA:3.40.50.880 286 543 4.8E-77 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 SUPERFAMILY SSF56645 117 355 1.28E-46 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Pfam PF09317 Domain of unknown function (DUF1974) 514 792 4.0E-118 T 28-03-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 360 504 4.4E-12 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Gene3D G3DSA:2.40.110.10 236 352 8.8E-17 T 28-03-2018 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 237 328 5.1E-9 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Gene3D G3DSA:1.20.140.10 353 508 3.2E-19 T 28-03-2018 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 147 232 2.3E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 SUPERFAMILY SSF47203 360 515 4.83E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS13725 b9f75feabcd6a689c58e6cbabb27e0aa 814 Gene3D G3DSA:1.10.540.10 76 235 6.8E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 SMART SM00650 25 198 4.0E-83 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 Gene3D G3DSA:3.40.50.150 2 203 1.0E-50 T 28-03-2018 WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 265 3.4E-86 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 265 54.75 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 SUPERFAMILY SSF53335 17 266 4.1E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 Gene3D G3DSA:1.10.8.100 204 264 5.8E-19 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 WM46_RS14565 29be33cf5bea7fc31778ff08f3ce978c 273 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 11 264 7.7E-90 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 WM46_RS21530 aab245e7444f41649b718f28dc50878a 169 Pfam PF00583 Acetyltransferase (GNAT) family 53 145 8.2E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS21530 aab245e7444f41649b718f28dc50878a 169 Gene3D G3DSA:3.40.630.30 1 152 5.1E-23 T 28-03-2018 WM46_RS21530 aab245e7444f41649b718f28dc50878a 169 SUPERFAMILY SSF55729 2 169 1.36E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS07410 e2d8c51ce78e9bd3a996e86b3508ea94 333 Hamap MF_00540 Adenosine deaminase [add]. 1 331 53.235 T 28-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 WM46_RS07410 e2d8c51ce78e9bd3a996e86b3508ea94 333 SUPERFAMILY SSF51556 5 326 6.43E-77 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS07410 e2d8c51ce78e9bd3a996e86b3508ea94 333 Gene3D G3DSA:3.20.20.140 4 333 9.8E-74 T 28-03-2018 WM46_RS07410 e2d8c51ce78e9bd3a996e86b3508ea94 333 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 274 280 - T 28-03-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 WM46_RS07410 e2d8c51ce78e9bd3a996e86b3508ea94 333 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 6 330 2.4E-107 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 WM46_RS07410 e2d8c51ce78e9bd3a996e86b3508ea94 333 Pfam PF00962 Adenosine/AMP deaminase 6 329 1.3E-101 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 WM46_RS23030 e8ee0f825f55cab9ae55d2f6a8d84a89 220 Hamap MF_01606 Iron-sulfur cluster repair protein YtfE [ytfE]. 1 220 52.354 T 28-03-2018 IPR023742 Iron-sulfur cluster repair protein YftE GO:0006950|GO:0030091 WM46_RS23030 e8ee0f825f55cab9ae55d2f6a8d84a89 220 Pfam PF04405 Domain of Unknown function (DUF542) 5 58 2.5E-20 T 28-03-2018 IPR019903 Repair of iron centres family WM46_RS23030 e8ee0f825f55cab9ae55d2f6a8d84a89 220 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 216 1.3E-80 T 28-03-2018 IPR019903 Repair of iron centres family WM46_RS23030 e8ee0f825f55cab9ae55d2f6a8d84a89 220 Gene3D G3DSA:1.10.3910.10 3 60 1.9E-12 T 28-03-2018 WM46_RS23030 e8ee0f825f55cab9ae55d2f6a8d84a89 220 Pfam PF01814 Hemerythrin HHE cation binding domain 77 216 1.6E-26 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 WM46_RS23030 e8ee0f825f55cab9ae55d2f6a8d84a89 220 Gene3D G3DSA:1.20.120.520 61 218 4.3E-31 T 28-03-2018 WM46_RS05010 7ab4510338c2f13c9fa6348e75878536 231 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 219 6.3E-69 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 WM46_RS05010 7ab4510338c2f13c9fa6348e75878536 231 SUPERFAMILY SSF53067 3 105 3.88E-30 T 28-03-2018 WM46_RS05010 7ab4510338c2f13c9fa6348e75878536 231 Gene3D G3DSA:3.30.420.40 145 231 0.0022 T 28-03-2018 WM46_RS05010 7ab4510338c2f13c9fa6348e75878536 231 SUPERFAMILY SSF53067 108 217 5.18E-31 T 28-03-2018 WM46_RS05010 7ab4510338c2f13c9fa6348e75878536 231 Gene3D G3DSA:3.30.420.40 1 138 4.4E-39 T 28-03-2018 WM46_RS05010 7ab4510338c2f13c9fa6348e75878536 231 Pfam PF00814 Glycoprotease family 28 133 9.6E-28 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 SUPERFAMILY SSF55973 112 232 2.47E-52 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 2 381 59.968 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 SUPERFAMILY SSF55973 233 382 7.46E-71 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 116 126 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Gene3D G3DSA:3.30.300.10 11 133 1.5E-44 T 28-03-2018 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Gene3D G3DSA:3.30.300.10 246 383 2.5E-49 T 28-03-2018 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 4 101 5.9E-43 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 370 5.0E-69 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 SUPERFAMILY SSF55973 3 109 2.08E-47 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Pfam PF02772 S-adenosylmethionine synthetase, central domain 114 231 7.2E-46 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 Gene3D G3DSA:3.30.300.10 134 233 1.3E-43 T 28-03-2018 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 PIRSF PIRSF000497 1 382 1.2E-175 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS15035 4be65e891eab48c6828637396ed85e6e 384 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 5 380 4.0E-200 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 Gene3D G3DSA:2.60.40.10 152 240 3.8E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 SUPERFAMILY SSF49584 143 238 1.7E-17 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 PRINTS PR00969 Pili chaperone signature 76 97 2.2E-30 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 PRINTS PR00969 Pili chaperone signature 27 36 2.2E-30 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 PRINTS PR00969 Pili chaperone signature 105 122 2.2E-30 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 PRINTS PR00969 Pili chaperone signature 166 181 2.2E-30 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 PRINTS PR00969 Pili chaperone signature 131 146 2.2E-30 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 Gene3D G3DSA:2.60.40.10 26 150 1.8E-35 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 104 121 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 SUPERFAMILY SSF49354 21 149 9.94E-39 T 28-03-2018 IPR008962 PapD-like WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 26 150 1.9E-41 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS07575 3604df713a22fc4b73055d58996b19fb 240 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 172 233 2.4E-14 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 392 46.891 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 Gene3D G3DSA:3.40.50.720 1 150 4.9E-53 T 28-03-2018 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 PIRSF PIRSF006205 1 398 3.0E-157 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 Gene3D G3DSA:1.10.1740.10 312 396 1.6E-30 T 28-03-2018 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 SUPERFAMILY SSF69055 301 394 3.53E-31 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 8.6E-49 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 387 5.2E-41 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 9.9E-36 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 397 1.8E-189 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 SUPERFAMILY SSF51735 2 150 1.47E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS13955 89fabd5ee2f3eb18f11190e0e96bc414 398 SUPERFAMILY SSF55347 126 274 1.34E-61 T 28-03-2018 WM46_RS14975 c6abe4d656e495982518912c8e280892 169 Pfam PF05068 Mannitol repressor 5 167 5.0E-50 T 28-03-2018 IPR007761 Mannitol repressor MtlR-like WM46_RS14975 c6abe4d656e495982518912c8e280892 169 Gene3D G3DSA:1.20.120.330 4 167 3.6E-45 T 28-03-2018 WM46_RS14975 c6abe4d656e495982518912c8e280892 169 SUPERFAMILY SSF158668 1 167 1.09E-52 T 28-03-2018 WM46_RS10810 d81a6cff9f9566226dd49a9151440dd4 402 Pfam PF06519 TolA C-terminal 307 400 4.0E-38 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 WM46_RS10810 d81a6cff9f9566226dd49a9151440dd4 402 TIGRFAM TIGR02794 tolA_full: protein TolA 223 402 2.7E-43 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 WM46_RS10810 d81a6cff9f9566226dd49a9151440dd4 402 TIGRFAM TIGR02794 tolA_full: protein TolA 12 242 1.4E-46 T 28-03-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 WM46_RS10810 d81a6cff9f9566226dd49a9151440dd4 402 Gene3D G3DSA:3.30.1150.10 325 397 1.0E-19 T 28-03-2018 WM46_RS10810 d81a6cff9f9566226dd49a9151440dd4 402 SUPERFAMILY SSF74653 315 402 3.73E-22 T 28-03-2018 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 3.9E-26 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 Gene3D G3DSA:2.60.300.12 2 107 8.8E-38 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 SUPERFAMILY SSF89360 1 96 2.75E-32 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 Hamap MF_01429 Iron-binding protein IscA [iscA]. 1 107 45.262 T 28-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.9E-61 T 28-03-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 WM46_RS00630 bd410dade68c3f67eaa9204cf2817a2e 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 8.2E-38 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 WM46_RS17225 bb9fc7598e77e7ef8bd32f55369f0a82 230 Gene3D G3DSA:2.40.160.40 26 230 7.4E-28 T 28-03-2018 WM46_RS17225 bb9fc7598e77e7ef8bd32f55369f0a82 230 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 16 230 1.5E-54 T 28-03-2018 IPR009331 Oligogalacturonate-specific porin WM46_RS17225 bb9fc7598e77e7ef8bd32f55369f0a82 230 SUPERFAMILY SSF56935 49 229 1.28E-6 T 28-03-2018 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 Gene3D G3DSA:1.10.10.10 1 89 6.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 7.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 7.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 7.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 Pfam PF03466 LysR substrate binding domain 92 292 1.3E-41 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 SUPERFAMILY SSF53850 93 293 8.22E-41 T 28-03-2018 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 SUPERFAMILY SSF46785 3 84 4.99E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 Gene3D G3DSA:3.40.190.10 93 183 1.5E-22 T 28-03-2018 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 Gene3D G3DSA:3.40.190.10 184 266 8.6E-22 T 28-03-2018 WM46_RS24790 b169f7b497cbe5e83b32aea393b350c9 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14305 368544564e8473c069f4aea8a3fe1f3a 461 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 281 295 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 WM46_RS14305 368544564e8473c069f4aea8a3fe1f3a 461 Pfam PF00437 Type II/IV secretion system protein 88 353 2.6E-84 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 WM46_RS14305 368544564e8473c069f4aea8a3fe1f3a 461 SUPERFAMILY SSF52540 84 454 8.24E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14305 368544564e8473c069f4aea8a3fe1f3a 461 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 8 70 3.6E-5 T 28-03-2018 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 WM46_RS14305 368544564e8473c069f4aea8a3fe1f3a 461 Gene3D G3DSA:3.40.50.300 187 461 4.4E-50 T 28-03-2018 WM46_RS14305 368544564e8473c069f4aea8a3fe1f3a 461 Gene3D G3DSA:3.30.450.90 49 186 1.6E-38 T 28-03-2018 WM46_RS06505 8b27db3517692892313f630287913f5b 289 Gene3D G3DSA:1.10.10.60 242 289 1.1E-15 T 28-03-2018 WM46_RS06505 8b27db3517692892313f630287913f5b 289 Pfam PF12833 Helix-turn-helix domain 209 287 2.0E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS06505 8b27db3517692892313f630287913f5b 289 SMART SM00342 203 286 7.9E-32 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS06505 8b27db3517692892313f630287913f5b 289 SUPERFAMILY SSF46689 239 288 1.3E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06505 8b27db3517692892313f630287913f5b 289 Gene3D G3DSA:1.10.10.60 183 241 1.7E-15 T 28-03-2018 WM46_RS06505 8b27db3517692892313f630287913f5b 289 SUPERFAMILY SSF46689 189 237 7.17E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06505 8b27db3517692892313f630287913f5b 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 270 286 7.4E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS06505 8b27db3517692892313f630287913f5b 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 255 270 7.4E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS06505 8b27db3517692892313f630287913f5b 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 240 282 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS12140 a0b50cacd3aafeaeb9180be3dff777d9 134 Pfam PF01807 CHC2 zinc finger 2 60 2.9E-22 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM46_RS12140 a0b50cacd3aafeaeb9180be3dff777d9 134 Gene3D G3DSA:3.90.580.10 1 119 3.5E-18 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM46_RS12140 a0b50cacd3aafeaeb9180be3dff777d9 134 SUPERFAMILY SSF57783 2 62 3.51E-20 T 28-03-2018 WM46_RS12140 a0b50cacd3aafeaeb9180be3dff777d9 134 SMART SM00400 21 71 2.6E-13 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 Pfam PF00158 Sigma-54 interaction domain 191 357 8.8E-48 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 SMART SM00382 210 355 3.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 SUPERFAMILY SSF52540 193 440 4.4E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 Gene3D G3DSA:3.40.50.300 186 365 6.1E-23 T 28-03-2018 WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 Gene3D G3DSA:3.40.50.10770 26 141 5.0E-7 T 28-03-2018 WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 PIRSF PIRSF037354 2 524 2.4E-259 T 28-03-2018 IPR017183 Sigma54-dependent transcriptional activator, RtcR GO:0003700|GO:0006355 WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 Pfam PF06956 Regulator of RNA terminal phosphate cyclase 3 188 7.9E-82 T 28-03-2018 IPR009715 Regulator of RNA terminal phosphate cyclase WM46_RS21470 385c8b18b8fdbf283d9cb303d6543b2d 526 Gene3D G3DSA:1.10.8.60 366 448 1.9E-14 T 28-03-2018 WM46_RS23365 120c08462045a06b52663cc9f3b80264 366 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 4 174 1.0E-67 T 28-03-2018 IPR005126 NapC/NirT cytochrome c, N-terminal WM46_RS23365 120c08462045a06b52663cc9f3b80264 366 SUPERFAMILY SSF48695 4 175 5.71E-45 T 28-03-2018 IPR011031 Multihaem cytochrome WM46_RS23365 120c08462045a06b52663cc9f3b80264 366 PIRSF PIRSF000014 1 366 1.3E-141 T 28-03-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 WM46_RS23365 120c08462045a06b52663cc9f3b80264 366 Gene3D G3DSA:3.90.10.10 36 363 1.1E-29 T 28-03-2018 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 SUPERFAMILY SSF55347 155 317 9.23E-58 T 28-03-2018 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 SUPERFAMILY SSF51735 1 179 9.17E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 4 328 4.3E-195 T 28-03-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 1.8E-54 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 Gene3D G3DSA:3.30.360.10 165 318 9.1E-53 T 28-03-2018 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 104 1.8E-34 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 2 337 65.871 T 28-03-2018 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 SMART SM00846 3 155 1.1E-80 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 PIRSF PIRSF000149 1 337 6.9E-134 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 7.0E-29 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 7.0E-29 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 7.0E-29 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 7.0E-29 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 7.0E-29 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14940 8fecd4738f33bb6a977a365930bcd10d 339 Gene3D G3DSA:3.40.50.720 1 164 4.6E-66 T 28-03-2018 WM46_RS22115 317809f239ea612167c1aa4601342e83 459 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 447 1.7E-63 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 WM46_RS22115 317809f239ea612167c1aa4601342e83 459 SUPERFAMILY SSF56954 2 447 3.01E-82 T 28-03-2018 WM46_RS22115 317809f239ea612167c1aa4601342e83 459 Gene3D G3DSA:1.20.1600.10 18 452 6.5E-68 T 28-03-2018 WM46_RS22115 317809f239ea612167c1aa4601342e83 459 Pfam PF02321 Outer membrane efflux protein 268 440 2.3E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS22115 317809f239ea612167c1aa4601342e83 459 Pfam PF02321 Outer membrane efflux protein 55 239 4.9E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS18985 5701f6b86ceca1cfeb22bceb8fda250d 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 WM46_RS18985 5701f6b86ceca1cfeb22bceb8fda250d 260 PIRSF PIRSF005902 1 260 1.1E-75 T 28-03-2018 IPR001130 TatD family GO:0016788 WM46_RS18985 5701f6b86ceca1cfeb22bceb8fda250d 260 Hamap MF_00901 3'-5' ssDNA/RNA exonuclease TatD [tatD]. 1 259 64.046 T 28-03-2018 IPR024918 3'-5' ssDNA/RNA exonuclease TatD GO:0008408 WM46_RS18985 5701f6b86ceca1cfeb22bceb8fda250d 260 SUPERFAMILY SSF51556 1 258 1.47E-84 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS18985 5701f6b86ceca1cfeb22bceb8fda250d 260 Gene3D G3DSA:3.20.20.140 1 260 3.2E-81 T 28-03-2018 WM46_RS18985 5701f6b86ceca1cfeb22bceb8fda250d 260 Pfam PF01026 TatD related DNase 2 256 5.7E-69 T 28-03-2018 IPR001130 TatD family GO:0016788 WM46_RS05155 77c95351b67e92f4cdb503efe61fbf7c 176 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 167 22.547 T 28-03-2018 IPR022920 Disulphide bond formation protein DsbB WM46_RS05155 77c95351b67e92f4cdb503efe61fbf7c 176 Pfam PF02600 Disulfide bond formation protein DsbB 12 159 3.2E-46 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 WM46_RS05155 77c95351b67e92f4cdb503efe61fbf7c 176 Gene3D G3DSA:1.20.1550.10 1 176 3.4E-55 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain WM46_RS05155 77c95351b67e92f4cdb503efe61fbf7c 176 SUPERFAMILY SSF158442 15 161 1.1E-45 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 Pfam PF02779 Transketolase, pyrimidine binding domain 353 523 6.0E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 Gene3D G3DSA:3.40.50.970 1 363 8.2E-125 T 28-03-2018 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 SUPERFAMILY SSF52922 532 663 1.31E-42 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 SMART SM00861 354 524 3.1E-65 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 4 663 0.0 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 ProSitePatterns PS00801 Transketolase signature 1. 11 31 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 Gene3D G3DSA:3.40.50.970 364 539 1.4E-40 T 28-03-2018 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 SUPERFAMILY SSF52518 4 320 8.04E-120 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 Pfam PF02780 Transketolase, C-terminal domain 539 654 4.4E-19 T 28-03-2018 IPR033248 Transketolase, C-terminal domain WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 SUPERFAMILY SSF52518 332 525 8.99E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 3 333 1.0E-171 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS00930 c61f41bef64f1f08c489baf31a31040a 664 Gene3D G3DSA:3.40.50.920 540 664 1.4E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS18110 7b3b64cf14b08ecbd67a104700d54882 237 SUPERFAMILY SSF52540 4 234 3.62E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18110 7b3b64cf14b08ecbd67a104700d54882 237 PIRSF PIRSF039137 1 237 2.2E-104 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 WM46_RS18110 7b3b64cf14b08ecbd67a104700d54882 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS18110 7b3b64cf14b08ecbd67a104700d54882 237 SMART SM00382 30 216 8.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18110 7b3b64cf14b08ecbd67a104700d54882 237 Pfam PF00005 ABC transporter 21 165 6.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18110 7b3b64cf14b08ecbd67a104700d54882 237 Gene3D G3DSA:3.40.50.300 1 237 3.6E-59 T 28-03-2018 WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 110 135 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 135 4.4E-16 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 SUPERFAMILY SSF51604 123 369 8.38E-50 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 Gene3D G3DSA:3.30.390.10 1 125 8.8E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 SMART SM00922 154 246 4.7E-11 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 195 226 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 Gene3D G3DSA:3.20.20.120 126 358 7.2E-43 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 Pfam PF13378 Enolase C-terminal domain-like 167 360 1.4E-37 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23545 2bb58db72ca0cb55bc9267cba56607fe 372 SUPERFAMILY SSF54826 1 138 1.77E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 Gene3D G3DSA:3.30.390.10 3 117 1.3E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 4.9E-35 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 SMART SM00922 128 259 4.6E-16 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 Gene3D G3DSA:3.20.20.120 118 373 1.3E-58 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 SUPERFAMILY SSF54826 1 112 8.77E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 SUPERFAMILY SSF51604 98 388 2.75E-80 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 Pfam PF13378 Enolase C-terminal domain-like 142 379 7.4E-43 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS07180 dedc7b8aca32158ac4588293156a61a5 404 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 209 240 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 137 2.6E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 SUPERFAMILY SSF50129 2 184 8.07E-43 T 28-03-2018 IPR011032 GroES-like WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 Gene3D G3DSA:3.90.180.10 2 184 2.9E-47 T 28-03-2018 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 SMART SM00829 13 335 1.3E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 Pfam PF00107 Zinc-binding dehydrogenase 179 299 7.3E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 172 199 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 SUPERFAMILY SSF51735 142 305 4.16E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 Gene3D G3DSA:3.90.180.10 259 337 0.038 T 28-03-2018 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM46_RS23465 a3f1ba54ee6b5cf07e338cc71fabfd06 339 Gene3D G3DSA:3.40.50.20 185 256 8.5E-18 T 28-03-2018 WM46_RS21670 0fdc9e6e24230f21fce952060574ed63 143 Gene3D G3DSA:3.40.50.620 2 143 6.0E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS21670 0fdc9e6e24230f21fce952060574ed63 143 PRINTS PR01438 Universal stress protein signature 104 116 8.6E-9 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS21670 0fdc9e6e24230f21fce952060574ed63 143 PRINTS PR01438 Universal stress protein signature 121 143 8.6E-9 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS21670 0fdc9e6e24230f21fce952060574ed63 143 SUPERFAMILY SSF52402 5 143 2.18E-24 T 28-03-2018 WM46_RS21670 0fdc9e6e24230f21fce952060574ed63 143 Pfam PF00582 Universal stress protein family 1 143 6.4E-23 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SUPERFAMILY SSF46955 403 475 5.4E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SMART SM00873 212 385 5.5E-101 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SUPERFAMILY SSF54991 696 794 5.23E-31 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:3.30.56.10 141 184 1.1E-8 T 28-03-2018 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:2.40.50.140 54 140 1.1E-44 T 28-03-2018 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SMART SM00874 403 471 1.3E-31 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Pfam PF01588 Putative tRNA binding domain 45 145 6.0E-28 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:3.50.40.10 195 395 2.0E-74 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SUPERFAMILY SSF50249 35 198 6.37E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SUPERFAMILY SSF55681 467 690 6.96E-57 T 28-03-2018 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:3.30.70.380 698 794 1.3E-23 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:3.30.930.10 489 690 7.9E-39 T 28-03-2018 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Pfam PF03483 B3/4 domain 212 385 9.2E-72 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 788 49.836 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Pfam PF03484 tRNA synthetase B5 domain 406 471 2.5E-21 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:3.30.56.10 402 475 3.5E-26 T 28-03-2018 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SMART SM00896 701 794 9.7E-46 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Pfam PF03147 Ferredoxin-fold anticodon binding domain 701 794 1.5E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 Gene3D G3DSA:3.30.56.10 1 53 3.4E-11 T 28-03-2018 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 794 2.1E-300 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 WM46_RS08010 7fb049fda8985926b191a751d5237775 795 SUPERFAMILY SSF56037 195 394 3.4E-78 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 183 730 5.0E-163 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 183 728 3.6E-181 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Gene3D G3DSA:3.30.70.100 46 118 3.9E-17 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Pfam PF00122 E1-E2 ATPase 234 414 2.2E-48 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Pfam PF00702 haloacid dehalogenase-like hydrolase 432 639 3.4E-34 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF81653 236 333 1.83E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Gene3D G3DSA:3.40.50.1000 555 693 3.9E-36 T 28-03-2018 IPR023214 HAD-like domain WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 436 442 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Gene3D G3DSA:3.40.1110.10 449 554 1.0E-27 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF55008 49 111 3.27E-16 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Pfam PF00403 Heavy-metal-associated domain 53 110 1.9E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 ProSitePatterns PS01047 Heavy-metal-associated domain. 54 83 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 Gene3D G3DSA:1.20.1110.10 124 448 2.4E-29 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 206 705 1.7E-79 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF81665 675 714 3.27E-19 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF81665 334 428 3.27E-19 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF81665 186 237 3.27E-19 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF56784 525 726 1.53E-49 T 28-03-2018 IPR023214 HAD-like domain WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 SUPERFAMILY SSF56784 433 452 1.53E-49 T 28-03-2018 IPR023214 HAD-like domain WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 626 642 7.5E-5 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 657 682 7.5E-5 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 564 9.6E-28 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 283 297 9.6E-28 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 448 9.6E-28 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 585 9.6E-28 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 661 9.6E-28 T 28-03-2018 WM46_RS18200 596ff4d8339df06d1a6c7b3956251700 732 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 645 9.6E-28 T 28-03-2018 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 SUPERFAMILY SSF63520 303 405 1.1E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 411 467 8.8E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 6 57 4.6E-7 T 28-03-2018 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 SUPERFAMILY SSF63520 186 286 3.14E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Gene3D G3DSA:1.10.10.10 85 152 3.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Gene3D G3DSA:1.10.10.10 1 69 1.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 SUPERFAMILY SSF52794 409 485 2.41E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Gene3D G3DSA:1.10.1790.10 192 290 1.1E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Pfam PF00874 PRD domain 203 286 8.1E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Pfam PF00874 PRD domain 313 402 6.4E-14 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Gene3D G3DSA:1.10.1790.10 302 406 7.9E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS09430 56f5ea62340850e0a2370ee83ec08727 501 Gene3D G3DSA:3.40.50.2300 407 496 1.8E-18 T 28-03-2018 WM46_RS24590 393dcda08b1c0fd543b5e6d700276384 301 SUPERFAMILY SSF49401 182 301 1.14E-26 T 28-03-2018 IPR008966 Adhesion domain WM46_RS24590 393dcda08b1c0fd543b5e6d700276384 301 SUPERFAMILY SSF49401 23 180 3.98E-64 T 28-03-2018 IPR008966 Adhesion domain WM46_RS24590 393dcda08b1c0fd543b5e6d700276384 301 Pfam PF00419 Fimbrial protein 176 301 4.7E-8 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24590 393dcda08b1c0fd543b5e6d700276384 301 Gene3D G3DSA:2.60.40.1090 181 301 2.6E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24590 393dcda08b1c0fd543b5e6d700276384 301 Gene3D G3DSA:2.60.40.1090 23 180 1.4E-60 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24590 393dcda08b1c0fd543b5e6d700276384 301 Pfam PF09160 FimH, mannose binding 25 168 8.7E-61 T 28-03-2018 IPR015243 FimH, mannose-binding domain WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Pfam PF00271 Helicase conserved C-terminal domain 480 588 2.1E-15 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 SUPERFAMILY SSF52540 205 453 1.18E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Gene3D G3DSA:1.10.150.20 2 51 3.3E-4 T 28-03-2018 WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Gene3D G3DSA:3.40.50.300 456 689 6.7E-25 T 28-03-2018 WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 28 664 8.3E-248 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Pfam PF17191 RecG wedge domain 14 171 1.2E-21 T 28-03-2018 IPR033454 RecG, wedge domain WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 SMART SM00490 505 589 4.0E-20 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Gene3D G3DSA:3.40.50.300 250 455 1.3E-35 T 28-03-2018 WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 SMART SM00487 265 459 2.4E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Pfam PF00270 DEAD/DEAH box helicase 292 433 9.0E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 Gene3D G3DSA:2.40.50.140 52 141 1.7E-11 T 28-03-2018 WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 SUPERFAMILY SSF50249 9 176 2.06E-43 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 SUPERFAMILY SSF52540 508 653 1.3E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20070 3864c9252497fe7c82fee4b8af131a95 693 SUPERFAMILY SSF52540 292 342 1.3E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01100 0d5b28e5d03d3ff1dcdad599bfb0f99f 238 SUPERFAMILY SSF52317 3 214 2.36E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS01100 0d5b28e5d03d3ff1dcdad599bfb0f99f 238 Pfam PF00117 Glutamine amidotransferase class-I 30 185 1.4E-13 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS01100 0d5b28e5d03d3ff1dcdad599bfb0f99f 238 Gene3D G3DSA:3.40.50.880 1 236 2.2E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 Gene3D G3DSA:1.20.1560.10 1 303 1.7E-21 T 28-03-2018 WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 Gene3D G3DSA:3.40.50.300 320 547 2.0E-41 T 28-03-2018 WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 SUPERFAMILY SSF52540 313 529 7.02E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 SUPERFAMILY SSF90123 5 299 1.1E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 SMART SM00382 348 533 6.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 2 527 2.0E-111 T 28-03-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 WM46_RS02105 2cd83576f1f085c3721869ba6de94256 547 Pfam PF00005 ABC transporter 341 477 4.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 Pfam PF01979 Amidohydrolase family 47 334 5.3E-7 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 PIRSF PIRSF039004 1 376 5.6E-132 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 SUPERFAMILY SSF51556 51 316 1.52E-72 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 3 364 4.3E-177 T 28-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 SUPERFAMILY SSF51338 317 365 2.21E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 SUPERFAMILY SSF51338 1 51 2.21E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 Gene3D G3DSA:2.30.40.10 1 57 5.3E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS23225 6b27248384d742cd5c3c9a2c5298658d 377 Gene3D G3DSA:3.20.20.140 58 315 2.9E-46 T 28-03-2018 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 Gene3D G3DSA:3.40.190.10 158 271 7.3E-5 T 28-03-2018 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 5 472 46.93 T 28-03-2018 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 SUPERFAMILY SSF53955 245 398 1.24E-34 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 SUPERFAMILY SSF53955 433 443 1.24E-34 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 SMART SM00062 44 269 6.5E-42 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 268 2.4E-28 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 SUPERFAMILY SSF53850 45 268 3.04E-34 T 28-03-2018 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 Gene3D G3DSA:1.10.530.10 273 451 2.3E-36 T 28-03-2018 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 310 338 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 Pfam PF01464 Transglycosylase SLT domain 297 402 1.1E-24 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS00460 64e486b5478e3ad2de940f157b425546 516 Gene3D G3DSA:3.40.190.10 34 150 1.8E-16 T 28-03-2018 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 PRINTS PR00969 Pili chaperone signature 26 35 4.8E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 PRINTS PR00969 Pili chaperone signature 71 92 4.8E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 PRINTS PR00969 Pili chaperone signature 99 116 4.8E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 PRINTS PR00969 Pili chaperone signature 160 175 4.8E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 PRINTS PR00969 Pili chaperone signature 125 140 4.8E-31 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 SUPERFAMILY SSF49584 144 223 1.7E-16 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS04205 8347df65e5927508ccf5b14186420800 230 SUPERFAMILY SSF49354 20 143 2.12E-40 T 28-03-2018 IPR008962 PapD-like WM46_RS04205 8347df65e5927508ccf5b14186420800 230 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 165 222 2.4E-9 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS04205 8347df65e5927508ccf5b14186420800 230 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 25 144 3.5E-40 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS04205 8347df65e5927508ccf5b14186420800 230 Gene3D G3DSA:2.60.40.10 25 144 3.2E-36 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS04205 8347df65e5927508ccf5b14186420800 230 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 98 115 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS04205 8347df65e5927508ccf5b14186420800 230 Gene3D G3DSA:2.60.40.10 145 230 9.1E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS01775 7aee74dd56df658ddde30445bbc61a70 166 Gene3D G3DSA:3.40.30.10 84 166 2.7E-14 T 28-03-2018 WM46_RS01775 7aee74dd56df658ddde30445bbc61a70 166 SUPERFAMILY SSF52833 16 165 9.28E-51 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS01775 7aee74dd56df658ddde30445bbc61a70 166 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 24 166 1.4E-50 T 28-03-2018 WM46_RS01775 7aee74dd56df658ddde30445bbc61a70 166 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 22 166 2.9E-52 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01775 7aee74dd56df658ddde30445bbc61a70 166 PIRSF PIRSF000216 1 166 6.1E-54 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01775 7aee74dd56df658ddde30445bbc61a70 166 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 123 141 - T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS16515 9a1c13c2887f31a58114fe8f766b49d4 351 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 47 265 1.5E-12 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS16515 9a1c13c2887f31a58114fe8f766b49d4 351 SUPERFAMILY SSF111369 35 272 1.05E-51 T 28-03-2018 WM46_RS16515 9a1c13c2887f31a58114fe8f766b49d4 351 Gene3D G3DSA:1.20.1600.10 71 269 1.1E-24 T 28-03-2018 WM46_RS16515 9a1c13c2887f31a58114fe8f766b49d4 351 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 23 348 5.7E-71 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS16515 9a1c13c2887f31a58114fe8f766b49d4 351 Gene3D G3DSA:2.40.50.100 30 70 5.5E-6 T 28-03-2018 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.536 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 Gene3D G3DSA:1.10.287.180 3 75 8.2E-33 T 28-03-2018 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 SUPERFAMILY SSF54534 81 157 6.28E-25 T 28-03-2018 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 1.8E-59 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 3.0E-29 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 7.0E-32 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 PIRSF PIRSF006092 1 158 2.8E-55 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 Gene3D G3DSA:3.10.50.30 76 158 2.4E-28 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM46_RS16830 950bdd8d8faae168f68480bc86a0535d 158 SUPERFAMILY SSF46557 3 78 4.97E-29 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 109 421 1.4E-104 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 Hamap MF_00504 Peptidase B [pepB]. 3 427 64.625 T 28-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 275 282 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 SUPERFAMILY SSF53187 107 426 2.23E-103 T 28-03-2018 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 Gene3D G3DSA:3.40.630.10 94 427 5.9E-113 T 28-03-2018 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 Pfam PF12404 Peptidase 5 81 2.4E-32 T 28-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 PRINTS PR00481 Cytosol aminopeptidase signature 190 207 3.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 PRINTS PR00481 Cytosol aminopeptidase signature 212 233 3.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 PRINTS PR00481 Cytosol aminopeptidase signature 249 270 3.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 PRINTS PR00481 Cytosol aminopeptidase signature 271 291 3.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 PRINTS PR00481 Cytosol aminopeptidase signature 299 314 3.4E-45 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00655 8db9244d6c3cb1f62939b1495a5b2975 427 PIRSF PIRSF036388 1 427 1.1E-237 T 28-03-2018 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.132 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.0E-40 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 Gene3D G3DSA:1.10.287.10 2 89 6.6E-37 T 28-03-2018 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 7.0E-40 T 28-03-2018 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 Pfam PF00312 Ribosomal protein S15 9 88 1.5E-37 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 SUPERFAMILY SSF47060 3 89 5.3E-35 T 28-03-2018 IPR009068 S15/NS1, RNA-binding WM46_RS16750 f0c95edb037e280ed1c68ea87612755d 89 SMART SM01387 8 88 6.6E-52 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 Gene3D G3DSA:3.40.47.10 267 390 3.6E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 SUPERFAMILY SSF53901 4 265 1.96E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 SUPERFAMILY SSF53901 271 392 5.94E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 Gene3D G3DSA:3.40.47.10 1 132 2.6E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 Gene3D G3DSA:3.40.47.10 150 266 2.2E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 Pfam PF00108 Thiolase, N-terminal domain 4 263 4.1E-104 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 Pfam PF02803 Thiolase, C-terminal domain 270 392 2.1E-52 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 8.3E-150 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 PIRSF PIRSF000429 1 394 4.1E-133 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS02040 e5d78701a1830af48f0c3bc6da7c41e3 394 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 Gene3D G3DSA:3.40.309.10 273 464 2.2E-70 T 28-03-2018 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 SUPERFAMILY SSF53720 6 481 4.19E-174 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 Pfam PF00171 Aldehyde dehydrogenase family 19 477 8.8E-173 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 476 5.2E-236 T 28-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 Gene3D G3DSA:3.40.605.10 7 272 3.7E-107 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS25725 ddcc3db4d4873852d6b2358eaa8bacb4 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 390 4.8E-197 T 28-03-2018 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 SUPERFAMILY SSF51905 274 386 3.21E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 SUPERFAMILY SSF51905 1 172 3.21E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 Gene3D G3DSA:3.50.50.60 3 168 4.5E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 Gene3D G3DSA:3.30.9.10 313 388 4.3E-13 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 Gene3D G3DSA:3.30.9.10 169 281 1.9E-45 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 Pfam PF01494 FAD binding domain 2 342 8.4E-84 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 2.7E-30 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.7E-30 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 2.7E-30 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 2.7E-30 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.7E-30 T 28-03-2018 WM46_RS23980 df61ca8d737169af17021d48eceb5c11 395 SUPERFAMILY SSF54373 175 275 1.29E-42 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 8 520 2.5E-235 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.3E-10 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.3E-10 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 Pfam PF02910 Fumarate reductase flavoprotein C-term 441 520 6.9E-14 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 SUPERFAMILY SSF56425 238 353 4.64E-40 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 PIRSF PIRSF000171 339 532 4.4E-14 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 PIRSF PIRSF000171 1 257 1.6E-21 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 Pfam PF00890 FAD binding domain 10 392 7.7E-103 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 377 4.2E-5 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.2E-5 T 28-03-2018 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 SUPERFAMILY SSF51905 356 447 2.53E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 SUPERFAMILY SSF51905 4 255 2.53E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 Gene3D G3DSA:1.20.58.100 439 539 7.5E-28 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 Gene3D G3DSA:3.50.50.60 1 438 9.0E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00365 2b569622750cdb7e9fab56cb1778a779 540 SUPERFAMILY SSF46977 425 525 9.94E-32 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS24195 4bd44a64357664d755515082f0014937 400 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 295 308 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 WM46_RS24195 4bd44a64357664d755515082f0014937 400 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 391 8.7E-135 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 WM46_RS24195 4bd44a64357664d755515082f0014937 400 SUPERFAMILY SSF51905 4 177 1.43E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24195 4bd44a64357664d755515082f0014937 400 SUPERFAMILY SSF51905 268 385 1.43E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24195 4bd44a64357664d755515082f0014937 400 Pfam PF01494 FAD binding domain 4 345 5.5E-31 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS24195 4bd44a64357664d755515082f0014937 400 Gene3D G3DSA:3.50.50.60 1 365 5.1E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24195 4bd44a64357664d755515082f0014937 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 8.6E-20 T 28-03-2018 WM46_RS24195 4bd44a64357664d755515082f0014937 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 8.6E-20 T 28-03-2018 WM46_RS24195 4bd44a64357664d755515082f0014937 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 8.6E-20 T 28-03-2018 WM46_RS24195 4bd44a64357664d755515082f0014937 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 8.6E-20 T 28-03-2018 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 Gene3D G3DSA:3.40.190.10 176 264 6.2E-29 T 28-03-2018 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 SUPERFAMILY SSF46785 1 86 1.27E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 Pfam PF03466 LysR substrate binding domain 89 292 3.6E-53 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.5E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 Gene3D G3DSA:3.40.190.10 87 175 7.3E-21 T 28-03-2018 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 Gene3D G3DSA:1.10.10.10 1 82 4.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21050 89ced598f62b2a1a673d40c90d3bdecf 305 SUPERFAMILY SSF53850 89 295 1.55E-46 T 28-03-2018 WM46_RS22765 632a9b868e3643141ba0c623f9a4ca17 44 Pfam PF08085 Entericidin EcnA/B family 23 43 3.2E-7 T 28-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 WM46_RS03350 390bc47f74ede4707a63a7f0b4f8eb45 361 PIRSF PIRSF004440 1 356 1.7E-75 T 28-03-2018 IPR026276 Baseplate protein GpP WM46_RS03350 390bc47f74ede4707a63a7f0b4f8eb45 361 SUPERFAMILY SSF69279 182 350 3.85E-45 T 28-03-2018 WM46_RS03350 390bc47f74ede4707a63a7f0b4f8eb45 361 SUPERFAMILY SSF69279 7 180 3.59E-50 T 28-03-2018 WM46_RS03350 390bc47f74ede4707a63a7f0b4f8eb45 361 Pfam PF05954 Phage late control gene D protein (GPD) 35 331 1.5E-10 T 28-03-2018 WM46_RS03350 390bc47f74ede4707a63a7f0b4f8eb45 361 Gene3D G3DSA:2.30.300.10 4 199 3.2E-58 T 28-03-2018 WM46_RS03350 390bc47f74ede4707a63a7f0b4f8eb45 361 Gene3D G3DSA:2.30.300.10 237 355 3.6E-23 T 28-03-2018 WM46_RS06410 4d7ac40172bd49e5444c7b292d0f4158 246 SUPERFAMILY SSF49482 10 240 8.9E-78 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 WM46_RS06410 4d7ac40172bd49e5444c7b292d0f4158 246 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 12 44 1.4E-14 T 28-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 WM46_RS06410 4d7ac40172bd49e5444c7b292d0f4158 246 Pfam PF00775 Dioxygenase 48 231 2.8E-54 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 WM46_RS06410 4d7ac40172bd49e5444c7b292d0f4158 246 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 18 239 3.3E-109 T 28-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 WM46_RS06410 4d7ac40172bd49e5444c7b292d0f4158 246 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 82 110 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 WM46_RS06410 4d7ac40172bd49e5444c7b292d0f4158 246 Gene3D G3DSA:2.60.130.10 3 240 7.5E-59 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 Gene3D G3DSA:3.40.50.720 2 143 3.1E-35 T 28-03-2018 WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 Gene3D G3DSA:3.30.360.10 144 418 9.3E-53 T 28-03-2018 WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 129 4.3E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 SUPERFAMILY SSF51735 4 156 8.2E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 SUPERFAMILY SSF55347 276 355 9.81E-25 T 28-03-2018 WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 SUPERFAMILY SSF55347 137 220 9.81E-25 T 28-03-2018 WM46_RS16570 5b9e0675c07a842ada43eef422b08a9e 418 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 227 1.2E-9 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS16725 ed9c367c59c539cd79d0c330f6a523be 335 Pfam PF00296 Luciferase-like monooxygenase 8 304 9.1E-36 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 WM46_RS16725 ed9c367c59c539cd79d0c330f6a523be 335 SUPERFAMILY SSF51679 6 327 2.47E-86 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 WM46_RS16725 ed9c367c59c539cd79d0c330f6a523be 335 Gene3D G3DSA:3.20.20.30 6 329 1.7E-71 T 28-03-2018 WM46_RS16725 ed9c367c59c539cd79d0c330f6a523be 335 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 326 1.7E-133 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 WM46_RS07195 f8c94ebee73ece5026af36214d926494 186 SUPERFAMILY SSF55729 7 164 5.4E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS07195 f8c94ebee73ece5026af36214d926494 186 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 3.2E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS07195 f8c94ebee73ece5026af36214d926494 186 Gene3D G3DSA:3.40.630.30 6 174 1.2E-32 T 28-03-2018 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 332 473 1.5E-64 T 28-03-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 Pfam PF00294 pfkB family carbohydrate kinase 13 305 1.8E-58 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 5 312 2.4E-129 T 28-03-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 SUPERFAMILY SSF52374 340 471 9.85E-22 T 28-03-2018 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 SUPERFAMILY SSF53613 12 309 2.65E-60 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 Gene3D G3DSA:3.40.50.620 319 477 2.3E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 Pfam PF01467 Cytidylyltransferase-like 345 468 6.6E-15 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 Gene3D G3DSA:3.40.1190.20 2 310 3.3E-60 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 342 408 1.1E-17 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS16195 06c4e722c8f6927d0b51ad570af8ac2c 477 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 43.686 T 28-03-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 SUPERFAMILY SSF100950 77 232 1.78E-27 T 28-03-2018 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 Pfam PF00455 DeoR C terminal sensor domain 77 232 5.6E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 Gene3D G3DSA:3.40.50.1360 67 232 6.6E-28 T 28-03-2018 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 23 37 2.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 37 55 2.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 SMART SM01134 74 234 5.9E-48 T 28-03-2018 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 SUPERFAMILY SSF46785 4 56 6.11E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 Gene3D G3DSA:1.10.10.10 1 57 2.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 SMART SM00420 5 57 6.0E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS24990 a8f23b5d9e87426129c9b417b5736fbe 234 Pfam PF08220 DeoR-like helix-turn-helix domain 5 59 1.8E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 90 2.0E-39 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 Gene3D G3DSA:2.60.15.10 1 90 1.2E-27 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 21.743 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 1.7E-29 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 Gene3D G3DSA:1.20.5.440 91 131 1.8E-13 T 28-03-2018 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 1.9E-46 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 133 2.7E-13 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 SUPERFAMILY SSF46604 88 137 1.83E-15 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19530 7c822d833aaa9ab068106d69b8936a09 139 SUPERFAMILY SSF51344 3 86 2.49E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS15400 21f642da00947002e0b09b0761132397 592 SMART SM00382 392 564 2.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS15400 21f642da00947002e0b09b0761132397 592 Gene3D G3DSA:3.40.50.300 345 575 9.3E-36 T 28-03-2018 WM46_RS15400 21f642da00947002e0b09b0761132397 592 SUPERFAMILY SSF52540 362 567 9.61E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15400 21f642da00947002e0b09b0761132397 592 Gene3D G3DSA:1.20.1560.10 19 344 1.3E-35 T 28-03-2018 WM46_RS15400 21f642da00947002e0b09b0761132397 592 Pfam PF06472 ABC transporter transmembrane region 2 20 293 2.8E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS15400 21f642da00947002e0b09b0761132397 592 Pfam PF00005 ABC transporter 384 521 1.2E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS15400 21f642da00947002e0b09b0761132397 592 SUPERFAMILY SSF90123 37 340 1.96E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS15400 21f642da00947002e0b09b0761132397 592 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 396 409 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS15400 21f642da00947002e0b09b0761132397 592 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 Gene3D G3DSA:3.40.50.720 1 162 4.4E-30 T 28-03-2018 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 Gene3D G3DSA:1.10.1040.10 163 294 7.8E-27 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 Hamap MF_01913 3-sulfolactaldehyde reductase. 1 292 61.612 T 28-03-2018 IPR030876 3-sulfolactaldehyde reductase GO:0061596|GO:1902777 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|MetaCyc: PWY-7446 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 9.4E-26 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 SUPERFAMILY SSF51735 3 160 5.38E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 PIRSF PIRSF000103 1 295 1.0E-98 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 160 5.0E-45 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 WM46_RS18780 4ae591ed156705d6b6934d87792095fe 296 SUPERFAMILY SSF48179 163 286 1.7E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 214 1.4E-99 T 28-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 Hamap MF_00496 Fructose-6-phosphate aldolase [fsa]. 1 220 49.853 T 28-03-2018 IPR023001 Fructose-6-phosphate aldolase GO:0016832 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 Gene3D G3DSA:3.20.20.70 1 219 5.0E-61 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 SUPERFAMILY SSF51569 1 218 3.02E-66 T 28-03-2018 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 ProSitePatterns PS00958 Transaldolase active site. 82 99 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS20940 45c320b97cca094e4deba1643eb0dfea 220 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 208 7.7E-48 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS12765 071e67b38d7f0ecd27cda2a47c991917 139 SUPERFAMILY SSF48013 3 136 5.49E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM46_RS12765 071e67b38d7f0ecd27cda2a47c991917 139 Gene3D G3DSA:1.10.940.10 1 138 1.2E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM46_RS12765 071e67b38d7f0ecd27cda2a47c991917 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 6 132 2.4E-45 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 WM46_RS12765 071e67b38d7f0ecd27cda2a47c991917 139 Pfam PF01029 NusB family 7 131 7.5E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM46_RS12765 071e67b38d7f0ecd27cda2a47c991917 139 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 4 135 23.616 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 PIRSF PIRSF003073 2 258 1.1E-89 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 Gene3D G3DSA:3.40.50.300 49 239 1.9E-17 T 28-03-2018 WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 SMART SM00382 102 236 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 Pfam PF01695 IstB-like ATP binding protein 57 235 4.5E-72 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 194 208 5.3E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 106 124 5.3E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS15465 e2f92cf9d44ae758e06c35aff7e1e665 260 SUPERFAMILY SSF52540 70 247 1.41E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19195 61ff6beb65b6c85024f1804462303204 246 Hamap MF_01001 UDP-N-acetyl-D-mannosaminuronic acid transferase [wecG]. 1 246 60.469 T 28-03-2018 IPR023085 UDP-N-acetyl-D-mannosaminuronic acid transferase GO:0009246|GO:0016758 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS19195 61ff6beb65b6c85024f1804462303204 246 Gene3D G3DSA:3.20.20.70 142 210 0.24 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS19195 61ff6beb65b6c85024f1804462303204 246 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 65 231 2.7E-53 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS19195 61ff6beb65b6c85024f1804462303204 246 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 61 237 7.1E-76 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Gene3D G3DSA:3.30.365.10 276 435 4.3E-43 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 SUPERFAMILY SSF54665 5 158 5.23E-40 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Gene3D G3DSA:3.30.365.10 600 764 1.7E-42 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 159 700 4.2E-163 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 SUPERFAMILY SSF56003 143 759 1.01E-177 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 139 2.1E-34 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Gene3D G3DSA:3.30.365.10 463 599 8.6E-38 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 SMART SM01008 23 139 7.0E-45 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Gene3D G3DSA:3.90.1170.50 1 139 4.6E-36 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead WM46_RS24385 04dcd74f0606766ee512089cd54da241 765 Gene3D G3DSA:3.30.365.10 168 275 1.5E-28 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 WM46_RS19980 27e74b1c2be58d1134db6f9bba96d0c2 853 Pfam PF00577 Outer membrane usher protein 204 756 5.2E-165 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS19980 27e74b1c2be58d1134db6f9bba96d0c2 853 Pfam PF13953 PapC C-terminal domain 766 830 5.1E-19 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS19980 27e74b1c2be58d1134db6f9bba96d0c2 853 Pfam PF13954 PapC N-terminal domain 43 188 1.6E-38 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS19980 27e74b1c2be58d1134db6f9bba96d0c2 853 SUPERFAMILY SSF141729 61 179 6.8E-28 T 28-03-2018 WM46_RS19980 27e74b1c2be58d1134db6f9bba96d0c2 853 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 315 325 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 115 4.9E-31 T 28-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 SUPERFAMILY SSF142019 94 303 6.02E-61 T 28-03-2018 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 139 283 3.7E-47 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 713 267.663 T 28-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Pfam PF12838 4Fe-4S dicluster domain 377 430 2.7E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Gene3D G3DSA:3.30.70.20 384 485 2.6E-16 T 28-03-2018 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Gene3D G3DSA:3.30.70.20 325 383 0.019 T 28-03-2018 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 SUPERFAMILY SSF46548 335 444 3.14E-19 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 13 445 8.7E-179 T 28-03-2018 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 416 427 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07445 fa59c213bab9e3ad014781c6c62175d2 713 Pfam PF10531 SLBB domain 296 344 1.1E-12 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 31.158 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 97 4.6E-55 T 28-03-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 Pfam PF00216 Bacterial DNA-binding protein 3 91 2.7E-30 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 3.1E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 3.1E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 3.1E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 Gene3D G3DSA:4.10.520.10 1 99 2.4E-33 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 SUPERFAMILY SSF47729 3 93 1.16E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS08005 59ec5d46b9f3ed5fc9297c10221bdeba 99 SMART SM00411 3 92 1.2E-43 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 Gene3D G3DSA:3.30.70.1450 217 306 2.3E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 Pfam PF03600 Citrate transporter 430 607 6.4E-21 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 Pfam PF03600 Citrate transporter 16 199 5.7E-38 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 SUPERFAMILY SSF116726 231 292 2.49E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 Pfam PF02080 TrkA-C domain 231 303 6.7E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 Pfam PF02080 TrkA-C domain 326 390 2.3E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 Gene3D G3DSA:3.30.70.1450 323 397 3.6E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 SUPERFAMILY SSF116726 322 393 3.14E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS01740 e9b834eb838954fbd798538e68f0572d 610 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 558 574 - T 28-03-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 Gene3D G3DSA:1.10.10.10 1 48 9.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 Gene3D G3DSA:1.10.10.10 131 236 0.31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 Pfam PF00665 Integrase core domain 236 339 4.7E-15 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 SUPERFAMILY SSF53098 235 382 2.15E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 Gene3D G3DSA:1.10.10.60 61 104 3.1E-8 T 28-03-2018 WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 Pfam PF13936 Helix-turn-helix domain 61 102 1.3E-12 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain WM46_RS15185 e8d5e0cbf7803e869509e71fa848c21e 386 Gene3D G3DSA:3.30.420.10 237 384 1.2E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS03505 cf62315943918d1265ddcb7d513c8389 173 Pfam PF02287 Dehydratase small subunit 39 170 2.3E-61 T 28-03-2018 IPR003207 Propanediol/glycerol dehydratase, small subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013 WM46_RS03505 cf62315943918d1265ddcb7d513c8389 173 PIRSF PIRSF018505 1 173 6.1E-77 T 28-03-2018 IPR003207 Propanediol/glycerol dehydratase, small subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013 WM46_RS03505 cf62315943918d1265ddcb7d513c8389 173 SUPERFAMILY SSF47148 37 173 1.83E-63 T 28-03-2018 IPR003207 Propanediol/glycerol dehydratase, small subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 57 95 5.2E-16 T 28-03-2018 IPR013575 Initiation factor 2 associated domain, bacterial WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Gene3D G3DSA:2.40.30.10 569 697 6.9E-30 T 28-03-2018 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 312 895 7.9E-298 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 ProSitePatterns PS01176 Initiation factor 2 signature. 846 868 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Pfam PF00009 Elongation factor Tu GTP binding domain 400 556 2.8E-35 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Gene3D G3DSA:2.40.30.10 796 894 3.5E-31 T 28-03-2018 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 SUPERFAMILY SSF52540 395 563 7.46E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 893 17.64 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Pfam PF11987 Translation-initiation factor 2 680 785 4.0E-36 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 1.3E-8 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 320 370 1.1E-14 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Gene3D G3DSA:3.40.50.10050 698 774 4.9E-25 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 SUPERFAMILY SSF46955 3 50 1.45E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Gene3D G3DSA:3.30.56.50 322 363 1.6E-9 T 28-03-2018 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Gene3D G3DSA:3.30.56.50 4 45 7.1E-11 T 28-03-2018 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 SUPERFAMILY SSF50447 797 893 4.12E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 SUPERFAMILY SSF50447 569 650 7.9E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 SUPERFAMILY SSF52156 673 802 3.66E-37 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 399 554 5.7E-34 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS16770 5f136fe4ebaa708e83094ecef4fa2fba 896 Gene3D G3DSA:3.40.50.300 379 568 1.1E-39 T 28-03-2018 WM46_RS07530 cfa79835b2aa138cfbd92ba6045a8c1a 173 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 34 172 1.6E-32 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 WM46_RS07530 cfa79835b2aa138cfbd92ba6045a8c1a 173 Gene3D G3DSA:2.60.40.200 19 173 2.4E-37 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 WM46_RS07530 cfa79835b2aa138cfbd92ba6045a8c1a 173 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 161 172 - T 28-03-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 WM46_RS07530 cfa79835b2aa138cfbd92ba6045a8c1a 173 SUPERFAMILY SSF49329 23 173 4.32E-48 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 WM46_RS01750 b8f438051dc296923845d0c600219d03 405 SUPERFAMILY SSF53383 7 401 1.01E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS01750 b8f438051dc296923845d0c600219d03 405 Gene3D G3DSA:3.40.640.10 53 280 5.5E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS01750 b8f438051dc296923845d0c600219d03 405 Gene3D G3DSA:3.90.1150.10 281 405 3.3E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS01750 b8f438051dc296923845d0c600219d03 405 Pfam PF00155 Aminotransferase class I and II 58 385 1.5E-45 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 Gene3D G3DSA:3.90.25.10 249 372 7.4E-35 T 28-03-2018 WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 Gene3D G3DSA:3.90.25.10 207 248 3.1E-22 T 28-03-2018 WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 346 6.4E-163 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 Gene3D G3DSA:3.40.50.720 1 206 2.3E-27 T 28-03-2018 WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 SUPERFAMILY SSF51735 2 353 1.47E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 353 7.8E-179 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 WM46_RS02840 a4f4286313713b6d9ae2f1f68ae487d3 373 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 356 56.775 T 28-03-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Pfam PF02875 Mur ligase family, glutamate ligase domain 312 360 1.0E-9 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Gene3D G3DSA:3.40.50.720 1 90 9.2E-12 T 28-03-2018 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 449 6.9E-269 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Gene3D G3DSA:3.40.1190.10 91 312 3.2E-37 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Pfam PF08245 Mur ligase middle domain 108 291 4.1E-18 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Pfam PF01225 Mur ligase family, catalytic domain 2 101 8.6E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 SUPERFAMILY SSF53244 312 447 4.19E-37 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 SUPERFAMILY SSF53623 95 308 1.57E-48 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 SUPERFAMILY SSF51984 1 90 3.01E-23 T 28-03-2018 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Gene3D G3DSA:3.90.190.20 313 451 2.3E-27 T 28-03-2018 WM46_RS23175 b0af635a30a1258d227b50b3eec02762 459 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 450 58.908 T 28-03-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 Gene3D G3DSA:3.40.50.2300 172 338 2.9E-32 T 28-03-2018 WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 SUPERFAMILY SSF53822 64 320 4.91E-55 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 SUPERFAMILY SSF47413 6 65 2.19E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 Gene3D G3DSA:1.10.260.40 5 60 3.9E-15 T 28-03-2018 WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 67 316 3.5E-21 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 54 1.2E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 SMART SM00354 6 77 7.4E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS20540 e31a09af284935ef1f3777c15d14b597 338 Gene3D G3DSA:3.40.50.2300 61 171 1.2E-31 T 28-03-2018 WM46_RS24180 6d04774cd77aa5a46258c37a503fe92f 194 Hamap MF_00346 UPF0149 protein YgfB [ygfB]. 8 192 37.8 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS24180 6d04774cd77aa5a46258c37a503fe92f 194 Pfam PF03695 Uncharacterised protein family (UPF0149) 14 179 1.0E-39 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS24180 6d04774cd77aa5a46258c37a503fe92f 194 SUPERFAMILY SSF101327 9 178 6.67E-54 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS24180 6d04774cd77aa5a46258c37a503fe92f 194 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 13 168 9.9E-14 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 SMART SM00304 339 393 4.4E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Gene3D G3DSA:3.30.450.20 188 317 5.1E-15 T 28-03-2018 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Gene3D G3DSA:3.30.450.20 80 187 4.4E-14 T 28-03-2018 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Gene3D G3DSA:1.10.287.950 337 449 5.9E-14 T 28-03-2018 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Gene3D G3DSA:1.10.287.950 450 643 5.6E-44 T 28-03-2018 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Pfam PF00672 HAMP domain 339 388 5.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 453 607 5.7E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 415 444 1.3E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 569 598 1.3E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 521 550 1.3E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 315 335 1.3E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 492 519 1.3E-50 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 Pfam PF02743 Cache domain 48 257 2.2E-20 T 28-03-2018 IPR033479 Double Cache domain 1 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 SMART SM00283 394 641 3.4E-72 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS06875 2532a0a89e39d3fcdac7a603f97bbc02 643 SUPERFAMILY SSF58104 361 642 1.23E-67 T 28-03-2018 WM46_RS00815 c026ec213ec687ef43a8c0bb952e76bb 280 Gene3D G3DSA:1.10.260.40 65 269 0.12 T 28-03-2018 WM46_RS00815 c026ec213ec687ef43a8c0bb952e76bb 280 Gene3D G3DSA:1.10.10.10 38 64 6.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS00815 c026ec213ec687ef43a8c0bb952e76bb 280 SUPERFAMILY SSF46689 21 107 5.47E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS00815 c026ec213ec687ef43a8c0bb952e76bb 280 Gene3D G3DSA:1.10.10.60 10 37 3.1E-6 T 28-03-2018 WM46_RS00815 c026ec213ec687ef43a8c0bb952e76bb 280 Pfam PF13384 Homeodomain-like domain 15 46 1.3E-5 T 28-03-2018 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Pfam PF04542 Sigma-70 region 2 16 88 1.7E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 PRINTS PR00046 Major sigma-70 factor signature 67 75 3.4E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 PRINTS PR00046 Major sigma-70 factor signature 189 201 3.4E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 PRINTS PR00046 Major sigma-70 factor signature 221 232 3.4E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 PRINTS PR00046 Major sigma-70 factor signature 43 56 3.4E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 PRINTS PR00046 Major sigma-70 factor signature 206 221 3.4E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 SUPERFAMILY SSF88659 89 156 5.23E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Gene3D G3DSA:1.10.10.10 89 136 4.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Gene3D G3DSA:1.10.1740.10 2 86 4.5E-22 T 28-03-2018 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 43 56 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 SUPERFAMILY SSF88946 5 88 3.66E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 16 236 2.4E-86 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Gene3D G3DSA:1.10.10.10 145 239 3.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 5 239 63.325 T 28-03-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 206 232 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 236 1.3E-33 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 SUPERFAMILY SSF88659 157 237 6.92E-20 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 PIRSF PIRSF000770 1 238 8.1E-42 T 28-03-2018 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Pfam PF04545 Sigma-70, region 4 185 233 1.2E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS03885 c9d78cd1f2882763ba95de073c2cc582 239 Pfam PF04539 Sigma-70 region 3 97 167 6.5E-19 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS11670 18b1c75800e0deb469a0439860108994 317 Gene3D G3DSA:1.10.10.60 1 54 3.5E-15 T 28-03-2018 WM46_RS11670 18b1c75800e0deb469a0439860108994 317 Pfam PF04198 Putative sugar-binding domain 63 314 2.2E-64 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 WM46_RS11670 18b1c75800e0deb469a0439860108994 317 SUPERFAMILY SSF100950 63 313 2.79E-66 T 28-03-2018 WM46_RS11670 18b1c75800e0deb469a0439860108994 317 SUPERFAMILY SSF46785 13 65 4.82E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11670 18b1c75800e0deb469a0439860108994 317 Gene3D G3DSA:3.40.50.1360 60 314 4.8E-41 T 28-03-2018 WM46_RS16825 a226985afc36e5fe693cbf51eee64eff 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 97 2.5E-42 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 WM46_RS16825 a226985afc36e5fe693cbf51eee64eff 97 SMART SM01103 3 86 4.2E-41 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM46_RS16825 a226985afc36e5fe693cbf51eee64eff 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 2.8E-22 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM46_RS16825 a226985afc36e5fe693cbf51eee64eff 97 SUPERFAMILY SSF75471 1 95 1.7E-31 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM46_RS16825 a226985afc36e5fe693cbf51eee64eff 97 Gene3D G3DSA:3.30.110.60 2 97 1.8E-28 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM46_RS16825 a226985afc36e5fe693cbf51eee64eff 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 97 3.0E-44 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 277 290 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 329 344 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 254 272 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 88 98 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 3.2E-68 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 Gene3D G3DSA:3.40.50.2300 153 332 7.8E-34 T 28-03-2018 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 Gene3D G3DSA:3.40.50.2300 10 152 3.2E-35 T 28-03-2018 WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 Pfam PF13458 Periplasmic binding protein 26 363 7.7E-61 T 28-03-2018 IPR028081 Leucine-binding protein domain WM46_RS18130 a1d572fd3d79600e888c6b8661643c09 369 SUPERFAMILY SSF53822 24 363 1.59E-89 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS19840 3d76bdce06a9b28d8a4545d1c8b0a7d1 500 Gene3D G3DSA:3.30.565.10 273 498 1.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19840 3d76bdce06a9b28d8a4545d1c8b0a7d1 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 412 498 2.3E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19840 3d76bdce06a9b28d8a4545d1c8b0a7d1 500 SUPERFAMILY SSF55874 381 497 5.76E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19840 3d76bdce06a9b28d8a4545d1c8b0a7d1 500 Pfam PF05231 MASE1 11 275 2.1E-13 T 28-03-2018 IPR007895 MASE1 WM46_RS19840 3d76bdce06a9b28d8a4545d1c8b0a7d1 500 SMART SM00387 409 499 6.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19840 3d76bdce06a9b28d8a4545d1c8b0a7d1 500 Pfam PF07730 Histidine kinase 305 370 2.1E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 PIRSF PIRSF500176 2 332 5.6E-117 T 28-03-2018 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 84 94 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 PIRSF PIRSF001220 1 334 5.2E-97 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 SMART SM00870 5 323 5.1E-140 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 8 16 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 Pfam PF00710 Asparaginase, N-terminal 6 187 7.1E-65 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 Gene3D G3DSA:3.40.50.1170 1 208 7.2E-80 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 SUPERFAMILY SSF53774 3 335 5.63E-112 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 PRINTS PR00139 Asparaginase/glutaminase family signature 6 17 4.5E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 PRINTS PR00139 Asparaginase/glutaminase family signature 83 101 4.5E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 PRINTS PR00139 Asparaginase/glutaminase family signature 260 278 4.5E-17 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 335 5.8E-136 T 28-03-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 WM46_RS08305 f2b301f03d4f0b3bf597beed4bbb5d77 338 Gene3D G3DSA:3.40.50.40 210 337 1.3E-41 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 PRINTS PR00969 Pili chaperone signature 98 115 1.7E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 PRINTS PR00969 Pili chaperone signature 24 33 1.7E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 PRINTS PR00969 Pili chaperone signature 157 172 1.7E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 PRINTS PR00969 Pili chaperone signature 70 91 1.7E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 PRINTS PR00969 Pili chaperone signature 122 137 1.7E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 SUPERFAMILY SSF49584 141 219 8.63E-24 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 Gene3D G3DSA:2.60.40.10 143 225 1.4E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 23 141 1.7E-42 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 97 114 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 Gene3D G3DSA:2.60.40.10 24 138 5.4E-38 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 162 218 3.7E-16 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24525 d9b3c915314b282ee2b8bb42ddc510c9 225 SUPERFAMILY SSF49354 18 140 7.85E-41 T 28-03-2018 IPR008962 PapD-like WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SUPERFAMILY SSF53850 59 267 1.45E-21 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SMART SM00062 304 523 2.6E-29 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SMART SM00062 58 280 4.3E-6 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 267 5.3E-16 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 305 520 2.9E-28 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:1.20.120.160 952 1060 1.7E-11 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SUPERFAMILY SSF53850 297 522 3.32E-32 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SMART SM00448 831 942 1.9E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:3.40.190.10 42 163 5.5E-17 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:3.40.190.10 288 418 3.2E-20 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 PRINTS PR00344 Bacterial sensor protein C-terminal signature 735 749 3.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 PRINTS PR00344 Bacterial sensor protein C-terminal signature 792 805 3.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 PRINTS PR00344 Bacterial sensor protein C-terminal signature 753 763 3.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 PRINTS PR00344 Bacterial sensor protein C-terminal signature 768 786 3.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SUPERFAMILY SSF55874 642 806 6.29E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SUPERFAMILY SSF47384 571 652 3.53E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Pfam PF00072 Response regulator receiver domain 833 940 3.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Pfam PF00512 His Kinase A (phospho-acceptor) domain 586 652 1.9E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:3.40.50.2300 823 951 1.1E-33 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:1.10.287.130 576 648 2.3E-15 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SMART SM00388 585 652 5.4E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SMART SM00387 699 808 9.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Pfam PF01627 Hpt domain 984 1054 4.9E-7 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:3.30.565.10 662 813 1.1E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:3.40.190.10 164 232 0.0021 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SUPERFAMILY SSF52172 830 958 1.35E-31 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Gene3D G3DSA:3.40.190.10 419 521 2.9E-6 T 28-03-2018 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 SUPERFAMILY SSF47226 925 1051 3.53E-13 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS24510 6dabeb5475ac3386ea7be4a6a98d8a80 1061 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 700 807 2.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 15 395 3.6E-160 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 25 41 - T 28-03-2018 IPR013061 Tryptophan/tryrosine permease, conserved site WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 45 64 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 327 345 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 155 175 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 90 110 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 293 312 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 348 367 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 232 251 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 18 41 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 PRINTS PR00166 Aromatic amino acid permease signature 193 215 2.1E-104 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS16730 dbec69bcf1fe36b8f98e9a30d9dcd9af 414 Pfam PF03222 Tryptophan/tyrosine permease family 10 402 6.6E-153 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 WM46_RS15815 d2bbb91159d46c6234bb259ad748230e 68 Gene3D G3DSA:1.10.10.10 16 68 2.8E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15815 d2bbb91159d46c6234bb259ad748230e 68 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 11 59 4.7E-10 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 SUPERFAMILY SSF54862 81 213 4.02E-34 T 28-03-2018 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Gene3D G3DSA:2.40.40.20 824 901 3.3E-13 T 28-03-2018 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 SMART SM00926 221 275 5.8E-9 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 221 274 2.2E-9 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 150 160 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 SMART SM00929 88 128 1.9E-19 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Pfam PF00384 Molybdopterin oxidoreductase 563 638 1.2E-7 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 SUPERFAMILY SSF53706 219 688 4.9E-84 T 28-03-2018 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 103 115 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 124 1.1E-14 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Gene3D G3DSA:3.40.50.740 281 414 3.2E-10 T 28-03-2018 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 655 1.2E-205 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 SUPERFAMILY SSF54292 1 77 7.44E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Gene3D G3DSA:3.40.50.740 471 663 2.1E-21 T 28-03-2018 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Gene3D G3DSA:2.20.25.90 214 280 3.1E-9 T 28-03-2018 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 SUPERFAMILY SSF50692 814 891 1.06E-13 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Gene3D G3DSA:3.10.20.30 1 165 1.3E-10 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Pfam PF01568 Molydopterin dinucleotide binding domain 828 890 5.3E-7 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS01785 b914ed78d1e7221a7ff1b6a1702792ce 908 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 78 2.5E-11 T 28-03-2018 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Gene3D G3DSA:3.40.1190.10 108 324 2.6E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14375 8950fefc86395352da3762809c765b48 491 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 21 475 1.6E-182 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Pfam PF08245 Mur ligase middle domain 124 304 4.0E-29 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14375 8950fefc86395352da3762809c765b48 491 SUPERFAMILY SSF51984 20 106 3.01E-29 T 28-03-2018 WM46_RS14375 8950fefc86395352da3762809c765b48 491 SUPERFAMILY SSF53623 105 322 1.83E-73 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Gene3D G3DSA:3.90.190.20 325 480 6.8E-34 T 28-03-2018 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 326 418 3.2E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Pfam PF01225 Mur ligase family, catalytic domain 21 118 1.6E-29 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 19 481 43.263 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14375 8950fefc86395352da3762809c765b48 491 SUPERFAMILY SSF53244 323 476 4.58E-44 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14375 8950fefc86395352da3762809c765b48 491 Gene3D G3DSA:3.40.50.720 1 107 2.3E-18 T 28-03-2018 WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SMART SM00487 106 443 2.6E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 Gene3D G3DSA:3.40.50.300 796 1314 1.1E-19 T 28-03-2018 WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 Pfam PF00270 DEAD/DEAH box helicase 125 218 1.2E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SUPERFAMILY SSF52540 125 151 6.03E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SUPERFAMILY SSF52540 1218 1318 6.03E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SUPERFAMILY SSF52540 190 217 6.03E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SUPERFAMILY SSF52540 105 159 2.28E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SUPERFAMILY SSF52540 311 408 2.28E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SUPERFAMILY SSF52540 187 235 2.28E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 SMART SM00490 1179 1289 0.0017 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 Pfam PF00271 Helicase conserved C-terminal domain 1242 1289 1.9E-6 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS05355 32ba6ee84628cc8070d02038396508a9 1983 Gene3D G3DSA:3.40.50.300 98 685 8.2E-18 T 28-03-2018 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 46.734 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 PIRSF PIRSF000813 1 408 4.1E-206 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Gene3D G3DSA:3.30.460.10 1 118 9.8E-31 T 28-03-2018 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 SUPERFAMILY SSF81301 2 119 6.54E-32 T 28-03-2018 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Pfam PF01966 HD domain 229 328 3.6E-12 T 28-03-2018 IPR006674 HD domain WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Gene3D G3DSA:1.10.3090.10 119 408 6.0E-60 T 28-03-2018 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 SUPERFAMILY SSF81891 120 404 7.19E-56 T 28-03-2018 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Pfam PF01743 Poly A polymerase head domain 3 122 5.9E-19 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 407 54.312 T 28-03-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 WM46_RS16220 7cea92f38b763be89121388415fe8d68 413 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 150 212 1.4E-15 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM46_RS22055 c04b410d367f6a6fa5e56c64238e4769 824 Pfam PF13953 PapC C-terminal domain 751 807 3.0E-13 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS22055 c04b410d367f6a6fa5e56c64238e4769 824 SUPERFAMILY SSF141729 31 147 2.09E-27 T 28-03-2018 WM46_RS22055 c04b410d367f6a6fa5e56c64238e4769 824 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 302 312 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS22055 c04b410d367f6a6fa5e56c64238e4769 824 Pfam PF13954 PapC N-terminal domain 32 173 2.8E-36 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS22055 c04b410d367f6a6fa5e56c64238e4769 824 Pfam PF00577 Outer membrane usher protein 191 740 4.5E-173 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11910 9935478ce5bba502553bc0531c8e4634 354 SUPERFAMILY SSF53474 183 350 6.42E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11910 9935478ce5bba502553bc0531c8e4634 354 SUPERFAMILY SSF53474 58 152 6.42E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11910 9935478ce5bba502553bc0531c8e4634 354 Gene3D G3DSA:3.40.50.1820 16 354 1.2E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11910 9935478ce5bba502553bc0531c8e4634 354 Pfam PF12697 Alpha/beta hydrolase family 81 298 4.6E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 73 92 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 184 201 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 54 72 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 210 228 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 233 250 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 255 273 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00691 Adhesin B signature 29 50 1.5E-35 T 28-03-2018 IPR006129 Adhesin B GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 Pfam PF01297 Zinc-uptake complex component A periplasmic 32 295 3.4E-72 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 Gene3D G3DSA:3.40.50.1980 22 174 2.9E-45 T 28-03-2018 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00690 Adhesin family signature 60 73 8.9E-42 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00690 Adhesin family signature 237 255 8.9E-42 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00690 Adhesin family signature 263 282 8.9E-42 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00690 Adhesin family signature 73 90 8.9E-42 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00690 Adhesin family signature 29 47 8.9E-42 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 PRINTS PR00690 Adhesin family signature 184 205 8.9E-42 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 SUPERFAMILY SSF53807 26 298 2.75E-90 T 28-03-2018 WM46_RS25340 7e448fc4fccafb4d6094f159393f32fe 305 Gene3D G3DSA:3.40.50.1980 175 298 7.0E-29 T 28-03-2018 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 ProSitePatterns PS00450 Aconitase family signature 1. 702 719 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Gene3D G3DSA:3.30.499.10 683 865 3.8E-54 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 4.0E-98 T 28-03-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 854 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Pfam PF11791 Aconitate B N-terminal domain 4 156 1.6E-68 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 SUPERFAMILY SSF53732 380 859 4.05E-149 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Gene3D G3DSA:3.20.19.10 162 363 2.2E-33 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 SUPERFAMILY SSF74778 2 160 1.44E-69 T 28-03-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Gene3D G3DSA:3.30.499.10 402 520 5.4E-10 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 PIRSF PIRSF036687 1 859 0.0 T 28-03-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Pfam PF00330 Aconitase family (aconitate hydratase) 472 818 1.5E-38 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 Gene3D G3DSA:3.40.1060.10 521 682 4.4E-26 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14230 224cedbef9251d2e2070e809363c047e 865 SUPERFAMILY SSF52016 162 371 7.59E-72 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS19970 5ace9a83dab830df05c9a7095e30e21c 185 Gene3D G3DSA:2.60.40.1090 28 185 1.6E-31 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS19970 5ace9a83dab830df05c9a7095e30e21c 185 Pfam PF16970 Type-1 fimbrial protein, A 56 185 1.6E-21 T 28-03-2018 WM46_RS19970 5ace9a83dab830df05c9a7095e30e21c 185 SUPERFAMILY SSF49401 29 185 1.09E-26 T 28-03-2018 IPR008966 Adhesion domain WM46_RS18635 a9958ce7ba29f5707def04c4c806a3fd 145 SUPERFAMILY SSF55804 8 145 1.96E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS18635 a9958ce7ba29f5707def04c4c806a3fd 145 Gene3D G3DSA:3.40.930.10 2 145 2.9E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS18635 a9958ce7ba29f5707def04c4c806a3fd 145 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 145 3.2E-28 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 Pfam PF00106 short chain dehydrogenase 3 197 1.0E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 Gene3D G3DSA:3.40.50.720 1 259 2.7E-53 T 28-03-2018 WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25490 cb6b15d360e4185822d9915f8211f846 259 SUPERFAMILY SSF51735 2 258 2.94E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 SUPERFAMILY SSF81464 29 116 8.34E-24 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 Gene3D G3DSA:2.60.40.420 114 281 1.3E-52 T 28-03-2018 IPR008972 Cupredoxin WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 149 218 4.1E-5 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 SUPERFAMILY SSF49503 120 282 8.59E-54 T 28-03-2018 IPR008972 Cupredoxin WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 Gene3D G3DSA:1.10.287.90 28 113 1.1E-19 T 28-03-2018 WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 Pfam PF06481 COX Aromatic Rich Motif 239 285 1.9E-18 T 28-03-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 13 239 5.2E-124 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 WM46_RS12665 cfb21c8f3095145e06c7797eb2dea090 318 PIRSF PIRSF000292 1 313 2.1E-133 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 SUPERFAMILY SSF46785 6 87 4.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 Pfam PF03466 LysR substrate binding domain 89 284 6.0E-18 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 Gene3D G3DSA:1.10.10.10 1 84 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 Gene3D G3DSA:3.40.190.10 90 180 2.5E-10 T 28-03-2018 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 SUPERFAMILY SSF53850 88 285 1.12E-23 T 28-03-2018 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 Gene3D G3DSA:3.40.190.10 181 260 2.8E-7 T 28-03-2018 WM46_RS24760 154255b31edcc30c39aaca2391e27a7f 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16645 de76b758d9ba86fef7735a4f5c2f70ef 263 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 5 263 4.5E-90 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS16645 de76b758d9ba86fef7735a4f5c2f70ef 263 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 4 263 5.5E-123 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 121 2.8E-24 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 262 276 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 PIRSF PIRSF000148 1 368 2.8E-71 T 28-03-2018 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 SMART SM00859 3 123 1.1E-24 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 Gene3D G3DSA:3.30.360.10 144 351 1.5E-60 T 28-03-2018 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 Gene3D G3DSA:3.40.50.720 1 143 1.3E-17 T 28-03-2018 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 SUPERFAMILY SSF55347 135 355 8.11E-79 T 28-03-2018 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 367 5.8E-223 T 28-03-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 354 1.7E-60 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 368 34.445 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS18035 a71ba8ea6f6b26b96d346860a26f8c9a 368 SUPERFAMILY SSF51735 1 148 1.22E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS13435 f24206414e5fd4c8da2b9a7b13344076 299 Gene3D G3DSA:3.40.50.1980 139 299 8.9E-31 T 28-03-2018 WM46_RS13435 f24206414e5fd4c8da2b9a7b13344076 299 Pfam PF01497 Periplasmic binding protein 39 267 1.0E-27 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS13435 f24206414e5fd4c8da2b9a7b13344076 299 SUPERFAMILY SSF53807 17 276 2.51E-58 T 28-03-2018 WM46_RS13435 f24206414e5fd4c8da2b9a7b13344076 299 Gene3D G3DSA:3.40.50.1980 14 138 5.5E-28 T 28-03-2018 WM46_RS18775 7fd9058793618371d5948043ae27877e 298 Hamap MF_00999 Sulfofructose kinase. 1 298 64.793 T 28-03-2018 IPR030877 Sulfofructose kinase GO:0061594 MetaCyc: PWY-7446 WM46_RS18775 7fd9058793618371d5948043ae27877e 298 PRINTS PR00990 Ribokinase signature 33 52 1.8E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS18775 7fd9058793618371d5948043ae27877e 298 PRINTS PR00990 Ribokinase signature 6 27 1.8E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS18775 7fd9058793618371d5948043ae27877e 298 PRINTS PR00990 Ribokinase signature 209 220 1.8E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS18775 7fd9058793618371d5948043ae27877e 298 Pfam PF00294 pfkB family carbohydrate kinase 2 286 3.3E-62 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS18775 7fd9058793618371d5948043ae27877e 298 SUPERFAMILY SSF53613 1 293 9.67E-67 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS18775 7fd9058793618371d5948043ae27877e 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS18775 7fd9058793618371d5948043ae27877e 298 Gene3D G3DSA:3.40.1190.20 1 296 1.2E-64 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 Gene3D G3DSA:3.40.47.10 259 403 1.5E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 SMART SM00825 Beta-ketoacyl synthase 4 405 1.1E-12 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 SUPERFAMILY SSF53901 1 252 8.64E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 SUPERFAMILY SSF53901 214 402 6.17E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 245 1.6E-39 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 153 169 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 360 4.5E-29 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM46_RS01535 80ad9c45eb0d181b7abafe21068c362b 405 Gene3D G3DSA:3.40.47.10 4 258 2.9E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 Gene3D G3DSA:3.40.250.10 156 283 9.8E-26 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 SMART SM00450 7 132 2.9E-29 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 SMART SM00450 155 275 1.2E-22 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 SUPERFAMILY SSF52821 165 279 2.62E-32 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 SUPERFAMILY SSF52821 3 150 1.7E-41 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 Pfam PF00581 Rhodanese-like domain 165 270 3.4E-10 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 Pfam PF00581 Rhodanese-like domain 9 128 3.3E-18 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 ProSitePatterns PS00683 Rhodanese C-terminal signature. 259 269 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 WM46_RS00670 85e65489eeb714b3fd6a25960b4c526c 283 Gene3D G3DSA:3.40.250.10 1 154 1.2E-34 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 SMART SM00354 1 71 7.5E-36 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 Gene3D G3DSA:3.40.50.2300 174 311 5.2E-42 T 28-03-2018 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 Gene3D G3DSA:3.40.50.2300 56 173 2.8E-30 T 28-03-2018 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 SUPERFAMILY SSF53822 60 332 1.22E-84 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 Gene3D G3DSA:1.10.260.40 2 55 1.6E-20 T 28-03-2018 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.1E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.6E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.6E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 SUPERFAMILY SSF47413 1 59 3.3E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS24805 c92c6aa3908294cad1063105053b8398 342 Pfam PF13377 Periplasmic binding protein-like domain 168 329 5.8E-36 T 28-03-2018 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 Pfam PF00919 Uncharacterized protein family UPF0004 9 95 2.1E-21 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 Pfam PF04055 Radical SAM superfamily 146 323 4.8E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 438 8.4E-109 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 SMART SM00729 140 365 8.5E-54 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 SUPERFAMILY SSF102114 107 371 3.01E-53 T 28-03-2018 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 144 164 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 8 440 63.431 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 9 438 2.4E-199 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 Gene3D G3DSA:2.40.50.140 380 441 1.9E-21 T 28-03-2018 WM46_RS10265 c465cdfeb629880cd7a5e75e11c75e6b 441 Gene3D G3DSA:3.80.30.20 137 379 7.2E-47 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe WM46_RS05080 af43275028df510181159ced5d5e89c0 326 Gene3D G3DSA:3.40.50.1100 163 326 1.9E-37 T 28-03-2018 WM46_RS05080 af43275028df510181159ced5d5e89c0 326 Gene3D G3DSA:3.40.50.1100 19 162 4.0E-40 T 28-03-2018 WM46_RS05080 af43275028df510181159ced5d5e89c0 326 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 308 2.7E-78 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS05080 af43275028df510181159ced5d5e89c0 326 SUPERFAMILY SSF53686 8 317 2.23E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 Pfam PF00696 Amino acid kinase family 6 234 1.7E-44 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 SUPERFAMILY SSF53633 6 256 4.71E-65 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 Gene3D G3DSA:2.30.130.10 274 366 1.1E-29 T 28-03-2018 IPR002478 PUA domain GO:0003723 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 PIRSF PIRSF000729 1 367 5.2E-146 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 SMART SM00359 276 359 1.7E-22 T 28-03-2018 IPR002478 PUA domain GO:0003723 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 207 224 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 SUPERFAMILY SSF88697 276 365 1.49E-23 T 28-03-2018 IPR015947 PUA-like domain WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 Gene3D G3DSA:3.40.1160.10 1 265 4.1E-63 T 28-03-2018 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 PRINTS PR00474 Glutamate 5-kinase family signature 116 137 1.6E-56 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 PRINTS PR00474 Glutamate 5-kinase family signature 76 104 1.6E-56 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 PRINTS PR00474 Glutamate 5-kinase family signature 209 229 1.6E-56 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 PRINTS PR00474 Glutamate 5-kinase family signature 42 56 1.6E-56 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 PRINTS PR00474 Glutamate 5-kinase family signature 148 175 1.6E-56 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 Pfam PF01472 PUA domain 276 350 2.0E-22 T 28-03-2018 IPR002478 PUA domain GO:0003723 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 5 365 9.1E-156 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM46_RS13650 8cec993245c427798359c2a6dd47efb9 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 5 259 36.034 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM46_RS06805 14fa3f1bee7bf246b0efb6b25e81f18b 94 Pfam PF01381 Helix-turn-helix 13 65 2.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS06805 14fa3f1bee7bf246b0efb6b25e81f18b 94 SMART SM00530 12 67 2.8E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS06805 14fa3f1bee7bf246b0efb6b25e81f18b 94 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 81 2.2E-27 T 28-03-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 WM46_RS06805 14fa3f1bee7bf246b0efb6b25e81f18b 94 Gene3D G3DSA:1.10.260.40 1 82 5.5E-14 T 28-03-2018 WM46_RS06805 14fa3f1bee7bf246b0efb6b25e81f18b 94 SUPERFAMILY SSF47413 9 87 4.74E-24 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 SUPERFAMILY SSF53850 15 264 1.35E-75 T 28-03-2018 WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 SMART SM00062 42 263 1.8E-85 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 Gene3D G3DSA:3.40.190.10 8 160 4.5E-47 T 28-03-2018 WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 65 78 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 1.4E-70 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 Gene3D G3DSA:3.40.190.10 161 265 4.2E-16 T 28-03-2018 WM46_RS03895 b4ba7b5c2ab70b681527289a73e9d3ae 266 SMART SM00079 42 262 5.3E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 WM46_RS10830 baef3cd07e5c33d7914938b4c0fcc416 97 TIGRFAM TIGR02112 cyd_oper_ybgE: cyd operon protein YbgE 5 97 5.5E-40 T 28-03-2018 IPR011846 Cyd operon protein YbgE WM46_RS10830 baef3cd07e5c33d7914938b4c0fcc416 97 Pfam PF09600 Cyd operon protein YbgE (Cyd_oper_YbgE) 17 95 2.6E-33 T 28-03-2018 IPR011846 Cyd operon protein YbgE WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 Gene3D G3DSA:3.40.50.300 254 492 1.7E-38 T 28-03-2018 WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 Pfam PF00005 ABC transporter 21 172 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 Pfam PF00005 ABC transporter 273 425 2.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 SUPERFAMILY SSF52540 244 483 7.68E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 SMART SM00382 280 474 2.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 SMART SM00382 30 226 6.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 Gene3D G3DSA:3.40.50.300 1 240 4.7E-49 T 28-03-2018 WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 SUPERFAMILY SSF52540 4 233 1.49E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18585 3d9cb766a34b18de83b870fc5c27c15a 501 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS13560 d68e11707f0e51eee4eb8ae00725e794 91 Gene3D G3DSA:1.10.10.10 7 88 0.0012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 Gene3D G3DSA:3.40.50.300 309 569 2.2E-33 T 28-03-2018 WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 SUPERFAMILY SSF52540 292 505 7.5E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 SUPERFAMILY SSF52540 8 203 4.27E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 Gene3D G3DSA:3.40.50.300 1 287 1.3E-42 T 28-03-2018 WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 SMART SM00382 29 205 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 SMART SM00382 322 503 2.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 Pfam PF00005 ABC transporter 319 443 1.5E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS06815 51e598d2892edef2d30a0a6e31cfc767 571 Pfam PF00005 ABC transporter 21 153 9.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Gene3D G3DSA:3.30.1370.20 435 518 9.6E-43 T 28-03-2018 IPR016173 D-lactate dehydrogenase, C-terminal subdomain 2 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 SUPERFAMILY SSF56176 10 271 3.08E-72 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Gene3D G3DSA:3.30.465.10 107 268 9.3E-79 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 SUPERFAMILY SSF55103 275 567 1.16E-117 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 PIRSF PIRSF000101 4 569 2.5E-304 T 28-03-2018 IPR012256 D-lactate dehydrogenase GO:0004457|GO:0005887|GO:0006089|GO:0050660|GO:0051287 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Gene3D G3DSA:3.30.43.10 1 104 1.3E-10 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Pfam PF01565 FAD binding domain 47 166 1.6E-7 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Pfam PF09330 D-lactate dehydrogenase, membrane binding 278 567 3.8E-147 T 28-03-2018 IPR015409 D-lactate dehydrogenase, membrane binding, C-terminal GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Gene3D G3DSA:3.30.70.610 349 434 5.0E-30 T 28-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 WM46_RS02565 9e5acb140e40f77ed857d8ccef5cbe48 573 Gene3D G3DSA:3.30.70.610 269 348 1.4E-20 T 28-03-2018 IPR016172 D-lactate dehydrogenase, C-terminal subdomain 1 GO:0006089|GO:0050660|GO:0055085 KEGG: 00620+1.1.1.28|MetaCyc: PWY-6454|MetaCyc: PWY-6901 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 PRINTS PR00446 Hydrogen uptake protein signature 56 66 7.7E-24 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 PRINTS PR00446 Hydrogen uptake protein signature 3 15 7.7E-24 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 PRINTS PR00446 Hydrogen uptake protein signature 35 52 7.7E-24 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 PRINTS PR00446 Hydrogen uptake protein signature 15 26 7.7E-24 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 PRINTS PR00446 Hydrogen uptake protein signature 68 84 7.7E-24 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 3 153 2.0E-54 T 28-03-2018 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 SUPERFAMILY SSF53163 1 159 9.16E-47 T 28-03-2018 IPR023430 Peptidase HybD-like domain WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 Pfam PF01750 Hydrogenase maturation protease 20 147 4.6E-37 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 Gene3D G3DSA:3.40.50.1450 1 162 2.3E-56 T 28-03-2018 IPR023430 Peptidase HybD-like domain WM46_RS15925 23e8c31eb45ea0b751dbd14e4768c7ff 164 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 148 1.6E-46 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS00545 d231db7c5ffa4fd7f24a25d1e4904b6f 426 Pfam PF00874 PRD domain 241 328 2.0E-11 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS00545 d231db7c5ffa4fd7f24a25d1e4904b6f 426 Pfam PF00874 PRD domain 132 216 4.1E-6 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS00545 d231db7c5ffa4fd7f24a25d1e4904b6f 426 Gene3D G3DSA:1.10.1790.10 227 333 1.1E-12 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS00545 d231db7c5ffa4fd7f24a25d1e4904b6f 426 SUPERFAMILY SSF63520 231 333 1.44E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 11 620 0.0 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 SUPERFAMILY SSF52922 491 619 1.01E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Pfam PF02779 Transketolase, pyrimidine binding domain 320 480 2.0E-39 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 12 282 2.7E-116 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 620 46.546 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Gene3D G3DSA:3.40.50.970 297 487 3.0E-62 T 28-03-2018 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 SUPERFAMILY SSF52518 317 504 1.28E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Gene3D G3DSA:3.40.50.920 495 620 1.8E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 SMART SM00861 319 484 2.1E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Gene3D G3DSA:3.40.50.970 3 296 9.6E-75 T 28-03-2018 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 Pfam PF02780 Transketolase, C-terminal domain 495 611 3.3E-26 T 28-03-2018 IPR033248 Transketolase, C-terminal domain WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 SUPERFAMILY SSF52518 10 199 2.75E-75 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS12745 7934a41a481635a549a630bb7bc7cf2c 620 SUPERFAMILY SSF52518 243 381 2.75E-75 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS23515 434253e82f0e0479dfcdb49b67f904ef 427 Gene3D G3DSA:1.20.1250.20 216 426 1.4E-28 T 28-03-2018 WM46_RS23515 434253e82f0e0479dfcdb49b67f904ef 427 Gene3D G3DSA:1.20.1250.20 1 202 6.3E-41 T 28-03-2018 WM46_RS23515 434253e82f0e0479dfcdb49b67f904ef 427 PIRSF PIRSF002808 1 426 1.3E-38 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS23515 434253e82f0e0479dfcdb49b67f904ef 427 SUPERFAMILY SSF103473 4 418 2.09E-87 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS23515 434253e82f0e0479dfcdb49b67f904ef 427 Pfam PF07690 Major Facilitator Superfamily 16 380 1.3E-61 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS08055 ae728358ce965047746eb8d4d75f95e8 272 Gene3D G3DSA:1.10.10.60 219 268 9.6E-4 T 28-03-2018 WM46_RS08055 ae728358ce965047746eb8d4d75f95e8 272 SMART SM00342 171 253 0.0059 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS08055 ae728358ce965047746eb8d4d75f95e8 272 Pfam PF12833 Helix-turn-helix domain 180 255 8.5E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 SMART SM00448 4 115 8.6E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 SUPERFAMILY SSF46689 380 469 1.68E-24 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Gene3D G3DSA:1.10.10.60 383 469 1.1E-26 T 28-03-2018 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Gene3D G3DSA:3.40.50.300 136 312 1.8E-28 T 28-03-2018 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 8.0E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 469 8.0E-11 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Gene3D G3DSA:1.10.8.60 313 382 2.6E-22 T 28-03-2018 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 SUPERFAMILY SSF52172 6 185 2.42E-47 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 SMART SM00382 160 311 7.8E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Pfam PF00072 Response regulator receiver domain 6 115 3.8E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 SUPERFAMILY SSF52540 139 383 5.51E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 6 466 9.4E-247 T 28-03-2018 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Gene3D G3DSA:3.40.50.2300 2 135 5.9E-37 T 28-03-2018 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Pfam PF02954 Bacterial regulatory protein, Fis family 427 466 1.7E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS18845 978df6ca4261f07ad6e4a6a52210bb52 469 Pfam PF00158 Sigma-54 interaction domain 140 306 9.4E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 211 221 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 SUPERFAMILY SSF51161 312 411 1.0E-18 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 21 397 2.1E-156 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 Pfam PF00483 Nucleotidyl transferase 22 291 1.5E-69 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 SUPERFAMILY SSF53448 378 393 8.21E-78 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 SUPERFAMILY SSF53448 20 294 8.21E-78 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 Gene3D G3DSA:2.160.10.10 334 419 5.1E-7 T 28-03-2018 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 26 45 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 Gene3D G3DSA:3.90.550.10 20 333 1.3E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 113 121 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 WM46_RS18020 f1fc3e90ab691048c99955f72c94db74 430 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 17 423 52.521 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 WM46_RS15760 c41ef081afaf4bf7775b01defbc125b2 306 Pfam PF08279 HTH domain 12 64 6.4E-5 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 WM46_RS15760 c41ef081afaf4bf7775b01defbc125b2 306 Pfam PF13280 WYL domain 129 289 8.2E-25 T 28-03-2018 IPR026881 WYL domain WM46_RS15760 c41ef081afaf4bf7775b01defbc125b2 306 Gene3D G3DSA:1.10.10.10 8 77 1.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16855 763325c84a96f90d1f2b430d54f3ef9a 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.6E-37 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16855 763325c84a96f90d1f2b430d54f3ef9a 103 SUPERFAMILY SSF141091 1 102 6.8E-37 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16855 763325c84a96f90d1f2b430d54f3ef9a 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 4.8E-45 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16855 763325c84a96f90d1f2b430d54f3ef9a 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.783 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16855 763325c84a96f90d1f2b430d54f3ef9a 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 313 1.5E-102 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 SUPERFAMILY SSF51569 1 316 3.56E-118 T 28-03-2018 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 TIGRFAM TIGR00874 talAB: transaldolase 4 316 6.5E-166 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 Gene3D G3DSA:3.20.20.70 2 316 9.1E-125 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS14785 14b8b972384f27d8953efefa40ef8ace 317 Hamap MF_00492 Transaldolase [tal]. 2 317 52.239 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Gene3D G3DSA:2.40.128.130 2786 3104 1.7E-42 T 28-03-2018 WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF103515 2805 3092 9.42E-41 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 1794 2047 1.38E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 1479 1647 1.38E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 1690 1754 1.38E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 2427 2783 4.08E-35 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2594 2624 2.8E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1499 1529 9.6E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1820 1851 7.2E-12 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2126 2157 6.3E-11 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2436 2467 1.8E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 2526 2556 3.6E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1428 1454 8.4E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 23 1.0E-8 T 28-03-2018 IPR024973 ESPR domain WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Gene3D G3DSA:2.160.20.20 845 1382 2.0E-12 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Gene3D G3DSA:2.160.20.20 2223 2785 9.7E-27 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 770 803 7800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 2454 2483 5200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 2317 2338 3000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 2704 2735 1600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 2892 2920 3000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 1149 1171 10000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00710 1088 1110 100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SMART SM00869 2825 3088 4.0E-35 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 1919 2248 3.45E-8 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 2669 3103 1.7E-53 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 1434 1453 0.0041 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 2526 2555 2.0E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 1821 1850 1.2E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 2127 2156 6.2E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 2597 2622 5.5E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 2439 2466 6.0E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 Pfam PF12951 Passenger-associated-transport-repeat 1499 1528 7.5E-5 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 2254 2292 2.07E-6 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS11825 57d65fc27c7ddeb670cef1fdbd558d51 3104 SUPERFAMILY SSF51126 2326 2494 2.07E-6 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS16245 9904f34628babfe7a99e6f15edf0bc1c 303 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 14 287 5.2E-121 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS16245 9904f34628babfe7a99e6f15edf0bc1c 303 Pfam PF05681 Fumarate hydratase (Fumerase) 16 284 3.4E-78 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 Gene3D G3DSA:1.10.10.10 2 70 4.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 SMART SM01134 87 248 8.2E-73 T 28-03-2018 WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 SUPERFAMILY SSF46785 16 71 5.17E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 SMART SM00420 18 70 4.8E-22 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 Pfam PF00455 DeoR C terminal sensor domain 89 247 5.2E-56 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 SUPERFAMILY SSF100950 89 250 1.36E-32 T 28-03-2018 WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 Pfam PF08220 DeoR-like helix-turn-helix domain 18 73 2.3E-20 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 ProSitePatterns PS00894 DeoR-type HTH domain signature. 18 52 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS16585 8b2546851f9e5bf7b852f107e100c4bd 267 Gene3D G3DSA:3.40.50.1360 79 253 1.3E-42 T 28-03-2018 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 Pfam PF00455 DeoR C terminal sensor domain 79 234 1.7E-37 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 Gene3D G3DSA:1.10.10.10 5 66 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 SUPERFAMILY SSF46785 9 62 7.68E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 SUPERFAMILY SSF100950 78 235 3.35E-22 T 28-03-2018 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 5.8E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 5.8E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 Gene3D G3DSA:3.40.50.1360 68 241 5.0E-27 T 28-03-2018 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 Pfam PF08220 DeoR-like helix-turn-helix domain 11 63 1.3E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 SMART SM00420 11 63 2.8E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS22545 cf794ff7cf2ce68ec0aaac6559b42d86 254 SMART SM01134 76 241 1.4E-45 T 28-03-2018 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 Gene3D G3DSA:1.10.260.40 2 55 3.0E-23 T 28-03-2018 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 Gene3D G3DSA:3.40.50.2300 179 300 1.8E-38 T 28-03-2018 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 SMART SM00354 1 71 9.0E-36 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 Gene3D G3DSA:3.40.50.2300 56 178 2.3E-23 T 28-03-2018 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 SUPERFAMILY SSF53822 60 332 3.34E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.4E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 SUPERFAMILY SSF47413 1 59 5.96E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS25445 b84f442fb4df31ada257e136ee182a05 337 Pfam PF13377 Periplasmic binding protein-like domain 171 331 2.2E-30 T 28-03-2018 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 472 597 1.6E-44 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 SUPERFAMILY SSF51261 467 616 5.76E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 Pfam PF00367 phosphotransferase system, EIIB 12 41 4.5E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 23 40 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 474 593 2.1E-38 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 535 547 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 Gene3D G3DSA:3.30.1360.60 8 84 3.2E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 Gene3D G3DSA:2.70.70.10 461 618 2.8E-50 T 28-03-2018 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 SUPERFAMILY SSF55604 10 84 1.83E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS15380 c4ed8989eb9c8407cc24391a0aa66ae1 618 Pfam PF02378 Phosphotransferase system, EIIC 107 389 7.1E-30 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Gene3D G3DSA:2.40.50.100 907 1021 8.6E-28 T 28-03-2018 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Gene3D G3DSA:2.40.50.100 1022 1126 2.4E-12 T 28-03-2018 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 1.0E-77 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 SMART SM00663 235 514 1.1E-184 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 393 1.2E-7 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Pfam PF00623 RNA polymerase Rpb1, domain 2 392 485 3.9E-27 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1374 18.998 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 1.7E-18 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Gene3D G3DSA:2.40.40.20 346 488 7.3E-40 T 28-03-2018 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1367 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 SUPERFAMILY SSF64484 1133 1363 0.0 T 28-03-2018 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 SUPERFAMILY SSF64484 16 944 0.0 T 28-03-2018 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Gene3D G3DSA:2.40.50.100 1153 1213 4.8E-14 T 28-03-2018 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.2E-89 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21195 1c26664f372c49c5af17512cac1dcc9b 1407 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 1.6E-26 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 2 235 1.1E-64 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 Pfam PF01709 Transcriptional regulator 4 235 2.1E-77 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 Gene3D G3DSA:3.30.70.980 82 174 2.8E-23 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 Gene3D G3DSA:3.30.70.980 181 236 9.7E-7 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 SUPERFAMILY SSF75625 2 235 1.57E-76 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 29.732 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.484 T 28-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN WM46_RS05250 d18f4da474a9123edbb742abdf5d2262 238 Gene3D G3DSA:1.10.10.200 2 76 8.7E-24 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 SMART SM01192 143 430 1.3E-214 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PIRSF PIRSF001400 1 430 2.4E-192 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 SUPERFAMILY SSF54826 3 138 2.5E-56 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 9.8E-206 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 Pfam PF03952 Enolase, N-terminal domain 4 134 8.0E-58 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 ProSitePatterns PS00164 Enolase signature. 339 352 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 429 5.3E-142 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PRINTS PR00148 Enolase signature 107 123 3.9E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PRINTS PR00148 Enolase signature 37 51 3.9E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PRINTS PR00148 Enolase signature 165 178 3.9E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PRINTS PR00148 Enolase signature 368 385 3.9E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PRINTS PR00148 Enolase signature 316 327 3.9E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 PRINTS PR00148 Enolase signature 339 353 3.9E-44 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 Gene3D G3DSA:3.20.20.120 128 430 3.8E-105 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 Gene3D G3DSA:3.30.390.10 3 127 9.0E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 SMART SM01193 4 134 6.0E-93 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 SUPERFAMILY SSF51604 143 427 4.95E-128 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25130 066135936bc56a798048e98a0b1da9d6 431 Hamap MF_00318 Enolase [eno]. 2 416 44.246 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS11610 361679055f5abe01217c62be7cb42b27 330 Gene3D G3DSA:1.10.3470.10 3 330 5.2E-62 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS11610 361679055f5abe01217c62be7cb42b27 330 SUPERFAMILY SSF81345 3 325 1.7E-71 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS11610 361679055f5abe01217c62be7cb42b27 330 Pfam PF01032 FecCD transport family 20 324 9.7E-83 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS23095 88bb21a9c1a689fcc4b897494011820a 340 SUPERFAMILY SSF51735 3 154 6.08E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23095 88bb21a9c1a689fcc4b897494011820a 340 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 192 4.3E-5 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS23095 88bb21a9c1a689fcc4b897494011820a 340 Gene3D G3DSA:3.30.360.10 139 340 2.6E-36 T 28-03-2018 WM46_RS23095 88bb21a9c1a689fcc4b897494011820a 340 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 116 4.6E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS23095 88bb21a9c1a689fcc4b897494011820a 340 SUPERFAMILY SSF55347 127 306 1.55E-26 T 28-03-2018 WM46_RS23095 88bb21a9c1a689fcc4b897494011820a 340 Gene3D G3DSA:3.40.50.720 1 138 1.3E-35 T 28-03-2018 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 SUPERFAMILY SSF64397 4 232 1.96E-76 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 Gene3D G3DSA:3.90.1280.10 226 281 1.4E-24 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 Pfam PF01430 Hsp33 protein 5 272 1.2E-85 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 Gene3D G3DSA:3.55.30.10 1 176 7.4E-62 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 Hamap MF_00117 33 kDa chaperonin [hslO]. 4 284 33.803 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 SUPERFAMILY SSF118352 225 283 1.01E-19 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 Gene3D G3DSA:1.10.287.480 181 225 2.2E-20 T 28-03-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain WM46_RS17840 30213cc7c324c38c4cd144d8e3a7a2f9 292 PIRSF PIRSF005261 1 285 4.4E-72 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 95 9.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 Gene3D G3DSA:1.10.10.10 26 103 4.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 SUPERFAMILY SSF48008 120 252 1.86E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 SUPERFAMILY SSF46785 28 99 3.74E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 Gene3D G3DSA:1.20.120.530 116 262 7.9E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 Pfam PF07729 FCD domain 125 246 1.7E-21 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 SMART SM00345 36 95 2.3E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 SMART SM00895 123 247 2.2E-17 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 Hamap MF_01236 Transcriptional regulator NanR [nanR]. 4 257 63.377 T 28-03-2018 IPR023730 HTH-type transcriptional repressor NanR WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 5.6E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS17020 c882c933a5a57f925ed3d81f944de164 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 5.6E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS16180 e475c9920072c61135f409ea72aa12bf 217 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 209 2.3E-84 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS16180 e475c9920072c61135f409ea72aa12bf 217 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 17 208 5.3E-82 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS16180 e475c9920072c61135f409ea72aa12bf 217 Gene3D G3DSA:3.90.870.10 3 217 1.9E-92 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS16180 e475c9920072c61135f409ea72aa12bf 217 SUPERFAMILY SSF55821 7 213 5.04E-85 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS16180 e475c9920072c61135f409ea72aa12bf 217 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 213 43.1 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS09420 98eb3263110c96308bc1b42da19b15dd 506 Pfam PF02264 LamB porin 100 505 2.3E-91 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS09420 98eb3263110c96308bc1b42da19b15dd 506 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 103 502 6.0E-136 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS09420 98eb3263110c96308bc1b42da19b15dd 506 Pfam PF11471 Maltoporin periplasmic N-terminal extension 16 55 5.0E-7 T 28-03-2018 IPR021570 LamB-type porin N-terminal domain WM46_RS09420 98eb3263110c96308bc1b42da19b15dd 506 Gene3D G3DSA:2.40.170.10 95 506 3.4E-104 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS09420 98eb3263110c96308bc1b42da19b15dd 506 SUPERFAMILY SSF56935 97 506 5.86E-117 T 28-03-2018 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 SMART SM00883 2 95 1.8E-48 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 PRINTS PR00297 10kDa chaperonin signature 25 46 1.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 PRINTS PR00297 10kDa chaperonin signature 3 18 1.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 PRINTS PR00297 10kDa chaperonin signature 60 72 1.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 PRINTS PR00297 10kDa chaperonin signature 82 95 1.9E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 Pfam PF00166 Chaperonin 10 Kd subunit 3 95 6.1E-29 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 Gene3D G3DSA:2.30.33.40 1 96 8.6E-32 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 23.933 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 WM46_RS22730 bf2f28338771592655e65e54b8064644 97 SUPERFAMILY SSF50129 1 96 1.65E-30 T 28-03-2018 IPR011032 GroES-like WM46_RS22730 bf2f28338771592655e65e54b8064644 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 386 854 4.6E-29 T 28-03-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 Gene3D G3DSA:2.60.40.1180 375 504 9.4E-18 T 28-03-2018 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 SUPERFAMILY SSF88713 6 272 8.15E-52 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 Gene3D G3DSA:3.20.110.10 2 249 4.6E-56 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 SUPERFAMILY SSF74650 375 849 1.16E-71 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 Gene3D G3DSA:1.20.1270.50 279 374 5.2E-18 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 7 271 6.9E-40 T 28-03-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 SMART SM00872 279 357 8.1E-17 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 SUPERFAMILY SSF88688 286 378 4.9E-8 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain WM46_RS10850 af1f6d8e17fba312ca4670cb7e5606b8 877 Pfam PF09261 Alpha mannosidase middle domain 280 356 1.8E-7 T 28-03-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 WM46_RS10440 e50c87078f05ce53f56f0f7230902f3f 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 37 67 1.5E-14 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 WM46_RS10440 e50c87078f05ce53f56f0f7230902f3f 88 SUPERFAMILY SSF57716 39 73 1.57E-8 T 28-03-2018 WM46_RS10440 e50c87078f05ce53f56f0f7230902f3f 88 PRINTS PR00618 DksA/TraR zinc finger signature 39 50 5.5E-6 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria WM46_RS10440 e50c87078f05ce53f56f0f7230902f3f 88 PRINTS PR00618 DksA/TraR zinc finger signature 51 63 5.5E-6 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria WM46_RS10440 e50c87078f05ce53f56f0f7230902f3f 88 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 39 63 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site WM46_RS10440 e50c87078f05ce53f56f0f7230902f3f 88 TIGRFAM TIGR02419 C4_traR_proteo: phage/conjugal plasmid C-4 type zinc finger protein, TraR family 9 67 3.7E-18 T 28-03-2018 IPR012783 Zinc finger, C4 DksA/TraR-type WM46_RS11410 4c84219c3a44f20b55c173239e8dae1e 87 SUPERFAMILY SSF117991 1 87 3.27E-31 T 28-03-2018 IPR027471 YbeD-like domain WM46_RS11410 4c84219c3a44f20b55c173239e8dae1e 87 Gene3D G3DSA:3.30.70.260 5 87 1.8E-30 T 28-03-2018 WM46_RS11410 4c84219c3a44f20b55c173239e8dae1e 87 Pfam PF04359 Protein of unknown function (DUF493) 7 87 7.3E-29 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 WM46_RS11410 4c84219c3a44f20b55c173239e8dae1e 87 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 87 26.407 T 28-03-2018 IPR007454 Uncharacterised protein family UPF0250 WM46_RS02165 f983565f742350536da446c20863e26d 206 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS02165 f983565f742350536da446c20863e26d 206 Gene3D G3DSA:3.40.50.300 1 203 1.5E-40 T 28-03-2018 WM46_RS02165 f983565f742350536da446c20863e26d 206 SMART SM00382 26 205 2.0E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02165 f983565f742350536da446c20863e26d 206 Pfam PF00005 ABC transporter 18 154 1.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS02165 f983565f742350536da446c20863e26d 206 SUPERFAMILY SSF52540 2 190 1.11E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02165 f983565f742350536da446c20863e26d 206 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 197 2.8E-83 T 28-03-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.4E-107 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 PIRSF PIRSF002155 1 227 3.2E-79 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.461 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 Gene3D G3DSA:3.40.50.790 68 149 6.2E-35 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 2.8E-52 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 Gene3D G3DSA:3.30.190.20 150 228 1.5E-21 T 28-03-2018 WM46_RS21170 fe571cbc137c0e0fb324fa04a95444e0 234 SUPERFAMILY SSF56808 6 225 5.1E-83 T 28-03-2018 IPR023674 Ribosomal protein L1-like WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 Gene3D G3DSA:2.40.160.20 28 229 2.1E-48 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 Pfam PF01389 OmpA-like transmembrane domain 42 217 4.2E-76 T 28-03-2018 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 SUPERFAMILY SSF103088 234 357 9.03E-36 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 336 349 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 263 282 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 202 216 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 302 321 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 126 142 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 188 202 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01022 Outer membrane protein A signature 234 249 1.1E-72 T 28-03-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01021 OMPA domain signature 246 268 9.5E-24 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01021 OMPA domain signature 293 309 9.5E-24 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 PRINTS PR01021 OMPA domain signature 278 293 9.5E-24 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 Pfam PF00691 OmpA family 245 340 1.0E-23 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 SUPERFAMILY SSF56925 41 218 3.4E-46 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 ProSitePatterns PS01068 OmpA-like domain. 280 324 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 WM46_RS09645 38d903e259f7f89934fbc82b676f5d83 369 Gene3D G3DSA:3.30.1330.60 230 368 2.9E-40 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS25205 abbb8844c127871fd89445238f4ded59 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 6 120 2.0E-33 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 WM46_RS25205 abbb8844c127871fd89445238f4ded59 120 SUPERFAMILY SSF55620 3 119 2.95E-40 T 28-03-2018 WM46_RS25205 abbb8844c127871fd89445238f4ded59 120 PIRSF PIRSF006113 1 120 1.3E-55 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 WM46_RS25205 abbb8844c127871fd89445238f4ded59 120 Gene3D G3DSA:3.30.479.10 1 120 1.5E-38 T 28-03-2018 WM46_RS25205 abbb8844c127871fd89445238f4ded59 120 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 5 96 5.6E-33 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 WM46_RS25205 abbb8844c127871fd89445238f4ded59 120 TIGRFAM TIGR00039 6PTHBS: 6-pyruvoyl tetrahydropterin synthase/QueD family protein 3 120 5.7E-38 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 WM46_RS06355 59869bb455cce3af72d3573a11da9880 479 SUPERFAMILY SSF53720 4 477 1.96E-158 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS06355 59869bb455cce3af72d3573a11da9880 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS06355 59869bb455cce3af72d3573a11da9880 479 Gene3D G3DSA:3.40.605.10 1 265 5.7E-92 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS06355 59869bb455cce3af72d3573a11da9880 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS06355 59869bb455cce3af72d3573a11da9880 479 Gene3D G3DSA:3.40.309.10 266 445 3.4E-66 T 28-03-2018 WM46_RS06355 59869bb455cce3af72d3573a11da9880 479 Pfam PF00171 Aldehyde dehydrogenase family 22 475 2.3E-163 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS23105 6b72ec43521e5ecfa6e6cce3cce08074 394 Gene3D G3DSA:3.30.360.10 138 354 3.3E-42 T 28-03-2018 WM46_RS23105 6b72ec43521e5ecfa6e6cce3cce08074 394 Gene3D G3DSA:3.40.50.720 1 137 3.5E-36 T 28-03-2018 WM46_RS23105 6b72ec43521e5ecfa6e6cce3cce08074 394 SUPERFAMILY SSF55347 129 259 3.6E-30 T 28-03-2018 WM46_RS23105 6b72ec43521e5ecfa6e6cce3cce08074 394 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 239 1.0E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS23105 6b72ec43521e5ecfa6e6cce3cce08074 394 SUPERFAMILY SSF51735 2 159 9.67E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23105 6b72ec43521e5ecfa6e6cce3cce08074 394 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 123 6.8E-28 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS22825 87d74155997e88436681d76d50d7f298 323 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 287 50.873 T 28-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 WM46_RS22825 87d74155997e88436681d76d50d7f298 323 Pfam PF02666 Phosphatidylserine decarboxylase 63 282 3.1E-58 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 WM46_RS22825 87d74155997e88436681d76d50d7f298 323 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 49 286 5.1E-101 T 28-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Gene3D G3DSA:3.40.50.300 92 297 6.8E-40 T 28-03-2018 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 SMART SM00962 100 296 4.1E-120 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 439 35.024 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 SMART SM00963 1 86 2.9E-37 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 7.3E-182 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.8E-23 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Gene3D G3DSA:1.20.120.140 1 91 1.3E-30 T 28-03-2018 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 SMART SM00382 99 247 7.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Gene3D G3DSA:1.10.260.30 328 432 5.7E-39 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Pfam PF02978 Signal peptide binding domain 329 427 4.3E-33 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 1.1E-75 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 SUPERFAMILY SSF52540 42 354 3.59E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00180 e92f50074ba7344103303ca0b7ba649b 453 SUPERFAMILY SSF47446 298 431 1.7E-46 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 Gene3D G3DSA:3.30.930.10 105 430 2.4E-96 T 28-03-2018 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 PIRSF PIRSF001529 1 430 5.0E-186 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 Gene3D G3DSA:1.10.287.40 2 104 1.9E-26 T 28-03-2018 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 SUPERFAMILY SSF55681 116 424 9.95E-100 T 28-03-2018 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 428 41.734 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 228 406 6.2E-37 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 PRINTS PR00981 Seryl-tRNA synthetase signature 282 295 1.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 PRINTS PR00981 Seryl-tRNA synthetase signature 270 282 1.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 PRINTS PR00981 Seryl-tRNA synthetase signature 322 335 1.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 PRINTS PR00981 Seryl-tRNA synthetase signature 339 355 1.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 1.1E-33 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 2.7E-33 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 SUPERFAMILY SSF46589 1 112 2.67E-32 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 WM46_RS09925 7f589c576b9813e01e57aac356a30137 430 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 423 7.0E-185 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 WM46_RS10270 686a9af74a378fd3c6032ecbcead2fc5 303 SUPERFAMILY SSF161098 96 283 2.88E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10270 686a9af74a378fd3c6032ecbcead2fc5 303 Gene3D G3DSA:1.10.3720.10 26 291 2.5E-45 T 28-03-2018 WM46_RS10270 686a9af74a378fd3c6032ecbcead2fc5 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 302 6.7E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10270 686a9af74a378fd3c6032ecbcead2fc5 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 69 8.1E-13 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 SUPERFAMILY SSF55252 87 155 1.44E-13 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 SUPERFAMILY SSF46785 10 78 5.86E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 Pfam PF02863 Arginine repressor, C-terminal domain 88 152 9.8E-13 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 Pfam PF01316 Arginine repressor, DNA binding domain 17 76 5.9E-13 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 139 0.004 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 PRINTS PR01467 Bacterial arginine repressor signature 46 61 1.0E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 PRINTS PR01467 Bacterial arginine repressor signature 29 42 1.0E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 PRINTS PR01467 Bacterial arginine repressor signature 125 140 1.0E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 PRINTS PR01467 Bacterial arginine repressor signature 95 108 1.0E-12 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 Gene3D G3DSA:3.30.1360.40 82 153 1.6E-16 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 Hamap MF_00173 Arginine repressor [argR]. 1 159 43.261 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS23325 41213cb54ec173aa3cff6cab0610afb7 159 Gene3D G3DSA:1.10.10.10 11 75 6.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07945 ddda45be24ea4b644846c16daa19b1da 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07945 ddda45be24ea4b644846c16daa19b1da 97 SUPERFAMILY SSF54862 43 91 3.31E-8 T 28-03-2018 WM46_RS07945 ddda45be24ea4b644846c16daa19b1da 97 Gene3D G3DSA:3.30.70.20 30 87 1.0E-5 T 28-03-2018 WM46_RS07945 ddda45be24ea4b644846c16daa19b1da 97 PIRSF PIRSF036548 3 97 1.6E-37 T 28-03-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 WM46_RS05325 758a194af925e4b49da1c1cf73bb543b 389 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 384 5.9E-116 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 WM46_RS05325 758a194af925e4b49da1c1cf73bb543b 389 Gene3D G3DSA:3.40.640.10 72 272 6.5E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS05325 758a194af925e4b49da1c1cf73bb543b 389 Pfam PF00155 Aminotransferase class I and II 62 379 7.7E-27 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS05325 758a194af925e4b49da1c1cf73bb543b 389 SUPERFAMILY SSF53383 17 384 1.21E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS05325 758a194af925e4b49da1c1cf73bb543b 389 Gene3D G3DSA:3.90.1150.10 273 383 1.3E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS05325 758a194af925e4b49da1c1cf73bb543b 389 Gene3D G3DSA:3.90.1150.10 1 71 9.9E-8 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 Pfam PF00654 Voltage gated chloride channel 89 437 5.0E-91 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 Hamap MF_01128 H(+)/Cl(-) exchange transporter ClcA [clcA]. 3 469 52.606 T 28-03-2018 IPR023861 Chloride channel, ClcA GO:0005887|GO:0006821|GO:0015108 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 SUPERFAMILY SSF81340 16 453 2.09E-111 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 Gene3D G3DSA:1.10.3080.10 16 461 1.7E-106 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 PRINTS PR00762 Chloride channel signature 352 372 9.0E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 PRINTS PR00762 Chloride channel signature 405 424 9.0E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 PRINTS PR00762 Chloride channel signature 102 119 9.0E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 PRINTS PR00762 Chloride channel signature 183 202 9.0E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS14040 bffe16c1f4dc7b6747fece78e9693a50 473 PRINTS PR00762 Chloride channel signature 387 403 9.0E-29 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS05575 115be5ef3816c90b2440e63f6650ba9e 284 SUPERFAMILY SSF51569 3 277 4.49E-103 T 28-03-2018 WM46_RS05575 115be5ef3816c90b2440e63f6650ba9e 284 Pfam PF00793 DAHP synthetase I family 10 275 9.7E-68 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS05575 115be5ef3816c90b2440e63f6650ba9e 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 275 5.9E-118 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS05575 115be5ef3816c90b2440e63f6650ba9e 284 Gene3D G3DSA:3.20.20.70 17 280 2.2E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS05575 115be5ef3816c90b2440e63f6650ba9e 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 277 49.532 T 28-03-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.6E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 3.2E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 61.059 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Gene3D G3DSA:2.40.30.10 300 393 1.8E-32 T 28-03-2018 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 5.6E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 4.8E-33 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 SUPERFAMILY SSF50465 298 393 4.32E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Gene3D G3DSA:3.40.50.300 75 203 9.9E-31 T 28-03-2018 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 393 5.7E-239 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Gene3D G3DSA:3.40.50.300 2 74 5.6E-11 T 28-03-2018 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 SUPERFAMILY SSF52540 6 219 2.02E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 Gene3D G3DSA:2.40.30.10 206 299 1.2E-32 T 28-03-2018 WM46_RS21150 8c1e24d1195d7759cfa576f33a585683 394 SUPERFAMILY SSF50447 205 301 2.16E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 SUPERFAMILY SSF52540 7 234 1.64E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 Gene3D G3DSA:3.40.50.300 257 495 2.5E-37 T 28-03-2018 WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 SUPERFAMILY SSF52540 261 489 7.38E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 Gene3D G3DSA:3.40.50.300 3 241 3.8E-51 T 28-03-2018 WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 SMART SM00382 32 222 2.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 SMART SM00382 283 478 0.0045 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 Pfam PF00005 ABC transporter 23 174 8.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS00570 03e2349223c9eb593b2e5630c5530cdc 502 Pfam PF00005 ABC transporter 275 429 1.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS13100 4cdadd15faee3fd66d40ee2f151a2df7 513 SUPERFAMILY SSF55874 395 505 2.75E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS13100 4cdadd15faee3fd66d40ee2f151a2df7 513 Pfam PF07730 Histidine kinase 316 380 8.3E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM46_RS13100 4cdadd15faee3fd66d40ee2f151a2df7 513 Gene3D G3DSA:3.30.565.10 340 507 9.3E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS13100 4cdadd15faee3fd66d40ee2f151a2df7 513 SMART SM00387 419 508 4.9E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS13100 4cdadd15faee3fd66d40ee2f151a2df7 513 Pfam PF05231 MASE1 11 281 1.6E-44 T 28-03-2018 IPR007895 MASE1 WM46_RS13100 4cdadd15faee3fd66d40ee2f151a2df7 513 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 506 1.6E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 Gene3D G3DSA:3.40.50.720 46 257 1.6E-58 T 28-03-2018 WM46_RS23570 25b2e75286092c5719edd723813939ea 257 Gene3D G3DSA:3.40.50.720 1 45 2.2E-7 T 28-03-2018 WM46_RS23570 25b2e75286092c5719edd723813939ea 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS23570 25b2e75286092c5719edd723813939ea 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 1.6E-59 T 28-03-2018 WM46_RS23570 25b2e75286092c5719edd723813939ea 257 SUPERFAMILY SSF51735 4 254 3.78E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23570 25b2e75286092c5719edd723813939ea 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10930 c55384e69d7e64c3804d15811969eb12 421 Pfam PF07005 Putative sugar-binding N-terminal domain 6 232 5.6E-67 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain WM46_RS10930 c55384e69d7e64c3804d15811969eb12 421 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 257 413 1.5E-37 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain WM46_RS10930 c55384e69d7e64c3804d15811969eb12 421 SUPERFAMILY SSF142764 6 418 6.67E-123 T 28-03-2018 WM46_RS10930 c55384e69d7e64c3804d15811969eb12 421 Gene3D G3DSA:3.40.50.10840 5 241 9.0E-74 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 Pfam PF00672 HAMP domain 175 223 2.1E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 468 556 1.5E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 SUPERFAMILY SSF158472 175 225 1.57E-7 T 28-03-2018 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 Pfam PF07730 Histidine kinase 361 425 1.8E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 Gene3D G3DSA:3.30.565.10 424 565 6.5E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 SMART SM00304 174 227 8.7E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 32 127 1.6E-22 T 28-03-2018 IPR029095 NarX-like, N-terminal WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 PIRSF PIRSF003167 1 301 2.5E-78 T 28-03-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 PIRSF PIRSF003167 288 568 5.6E-102 T 28-03-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 SMART SM00387 465 559 1.1E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 Gene3D G3DSA:1.20.58.60 32 261 0.028 T 28-03-2018 WM46_RS00905 a6301f80c97aa721f77f89a5a58ee2ee 568 SUPERFAMILY SSF55874 424 555 1.7E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 Gene3D G3DSA:4.10.520.10 1 94 6.4E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 7.7E-30 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 5.1E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 5.1E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 5.1E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 93 2.6E-53 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 SUPERFAMILY SSF47729 1 91 1.44E-29 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 SMART SM00411 1 91 4.9E-43 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS09845 bb4ab413139efe1e55b7a88fcc10ae28 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 30.373 T 28-03-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 348 361 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 SUPERFAMILY SSF55785 188 293 2.09E-10 T 28-03-2018 IPR000014 PAS domain WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Gene3D G3DSA:3.40.50.10660 89 168 9.2E-15 T 28-03-2018 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Gene3D G3DSA:1.10.10.60 596 636 5.2E-6 T 28-03-2018 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 SMART SM00091 197 263 6.7E-6 T 28-03-2018 IPR000014 PAS domain WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Pfam PF00158 Sigma-54 interaction domain 325 491 2.9E-67 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 SUPERFAMILY SSF159800 9 187 2.48E-36 T 28-03-2018 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Gene3D G3DSA:3.30.450.20 183 305 2.2E-10 T 28-03-2018 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Gene3D G3DSA:1.10.8.60 497 595 1.5E-11 T 28-03-2018 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Pfam PF00989 PAS fold 198 248 4.6E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 194 260 1.2E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Gene3D G3DSA:3.40.50.300 317 496 4.8E-26 T 28-03-2018 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Pfam PF06506 Propionate catabolism activator 33 192 3.9E-39 T 28-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 SUPERFAMILY SSF46689 532 634 2.51E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 SMART SM00382 344 489 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 SUPERFAMILY SSF52540 324 550 3.52E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23720 29689a563e9210198b0ebac92562eb75 637 Gene3D G3DSA:3.40.50.2300 4 88 2.3E-12 T 28-03-2018 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 Gene3D G3DSA:2.40.170.20 256 774 1.3E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 Pfam PF07715 TonB-dependent Receptor Plug Domain 132 244 2.5E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 Pfam PF00593 TonB dependent receptor 329 772 1.0E-48 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 SMART SM00965 56 107 3.7E-12 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 SUPERFAMILY SSF56935 117 774 1.22E-120 T 28-03-2018 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 132 774 1.1E-160 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 Pfam PF07660 Secretin and TonB N terminus short domain 58 105 2.0E-7 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 757 774 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS13430 215bfc699fd9ef159e4a6632664347ab 774 Gene3D G3DSA:2.170.130.10 128 255 9.6E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 Pfam PF08841 Diol dehydratase reactivase ATPase-like domain 275 602 1.6E-163 T 28-03-2018 IPR030994 Diol dehydratase reactivase ATPase-like domain WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 TIGRFAM TIGR04491 reactive_PduG: diol dehydratase reactivase alpha subunit 3 601 1.6E-286 T 28-03-2018 IPR009191 Diol dehydratase-reactivating factor alpha subunit WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 Gene3D G3DSA:3.30.420.40 1 107 9.5E-16 T 28-03-2018 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 Gene3D G3DSA:3.30.420.40 510 610 1.2E-18 T 28-03-2018 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 Gene3D G3DSA:3.30.420.40 280 411 0.0029 T 28-03-2018 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 SUPERFAMILY SSF53067 255 403 4.14E-70 T 28-03-2018 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 SUPERFAMILY SSF53067 3 93 4.14E-70 T 28-03-2018 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 SUPERFAMILY SSF82317 93 254 1.83E-67 T 28-03-2018 IPR028975 Diol dehydratase-reactivating factor, alpha subunit, swiveling domain WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 SUPERFAMILY SSF53067 407 600 1.44E-33 T 28-03-2018 WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 Gene3D G3DSA:3.50.30.70 108 247 1.3E-67 T 28-03-2018 IPR028975 Diol dehydratase-reactivating factor, alpha subunit, swiveling domain WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 PIRSF PIRSF011502 1 608 0.0 T 28-03-2018 IPR009191 Diol dehydratase-reactivating factor alpha subunit WM46_RS03500 851fce6b4fcfd9df3d9adbd4667c5430 610 Gene3D G3DSA:2.40.50.140 466 509 5.9E-25 T 28-03-2018 WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 Pfam PF00072 Response regulator receiver domain 3 113 3.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 SMART SM00448 1 112 1.3E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 SMART SM00862 146 221 2.1E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 Gene3D G3DSA:1.10.10.10 121 227 8.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.2E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 Gene3D G3DSA:3.40.50.2300 1 120 3.9E-32 T 28-03-2018 WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 SUPERFAMILY SSF52172 1 177 1.96E-38 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS11860 2a435c1c758884b539398d2b0a6f85f9 227 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 1.1E-97 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 Pfam PF00364 Biotin-requiring enzyme 82 154 9.1E-25 T 28-03-2018 IPR000089 Biotin/lipoyl attachment WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 155 2.7E-69 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 116 129 1.9E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 84 97 1.9E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 101 115 1.9E-18 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 SUPERFAMILY SSF51230 80 155 5.63E-26 T 28-03-2018 IPR011053 Single hybrid motif WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 Gene3D G3DSA:2.40.50.100 4 155 2.3E-21 T 28-03-2018 WM46_RS17210 4efb8db15dfe5332b14c983ceb860a41 155 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 111 128 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM46_RS21800 2a4b64855cae70a653abe02ef9810e7e 206 SUPERFAMILY SSF48452 70 184 9.76E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS21800 2a4b64855cae70a653abe02ef9810e7e 206 Gene3D G3DSA:1.25.40.10 41 121 1.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS21800 2a4b64855cae70a653abe02ef9810e7e 206 SMART SM00028 81 114 0.3 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS21800 2a4b64855cae70a653abe02ef9810e7e 206 SMART SM00028 152 185 35.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS21800 2a4b64855cae70a653abe02ef9810e7e 206 Gene3D G3DSA:1.25.40.10 122 202 2.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS14105 0a5d86302bfa9d8883db13141f3053bc 159 SUPERFAMILY SSF55083 1 154 4.58E-53 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM46_RS14105 0a5d86302bfa9d8883db13141f3053bc 159 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM46_RS14105 0a5d86302bfa9d8883db13141f3053bc 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 6.0E-35 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM46_RS14105 0a5d86302bfa9d8883db13141f3053bc 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 134 1.5E-44 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM46_RS14105 0a5d86302bfa9d8883db13141f3053bc 159 Gene3D G3DSA:3.30.70.560 1 158 3.3E-54 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 SMART SM00912 46 168 5.9E-50 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF04829 Pre-toxin domain with VENN motif 3292 3343 2.2E-14 T 28-03-2018 IPR006914 VENN motif-containing domain WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13930 DNA/RNA non-specific endonuclease 3490 3613 8.7E-32 T 28-03-2018 WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 828 986 9.7E-11 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 1237 1306 3.5E-5 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 322 423 1.2E-6 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 987 1071 1.1E-4 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 424 502 1.3E-4 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 1086 1236 9.2E-5 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 32 321 1.5E-59 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 660 780 2.9E-10 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 781 827 0.0034 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 1423 1668 0.0025 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 2044 2184 0.0014 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 2185 2385 5.9E-5 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Gene3D G3DSA:2.160.20.10 1822 2043 1.3E-8 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 2006 2073 1.0E-9 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 2555 2659 1.1E-7 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 1945 1991 0.0035 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 2443 2547 1.2E-11 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 2216 2347 2.7E-10 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 2131 2205 9.1E-7 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF13332 Haemagluttinin repeat 2783 2947 2.6E-41 T 28-03-2018 IPR025157 Hemagglutinin repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 Pfam PF05860 haemagglutination activity domain 37 166 1.1E-32 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 SUPERFAMILY SSF51126 40 311 1.07E-60 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1845 1883 4.1E-4 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 394 429 0.25 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1094 1119 0.61 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 999 1035 2.2 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1885 1905 0.12 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1016 1047 0.23 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1456 1492 0.0074 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 958 995 0.13 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 738 774 0.016 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1252 1292 0.034 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 923 956 1.1 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 774 810 0.12 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 755 793 3.1E-5 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1055 1089 0.0087 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 582 620 2.2 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 622 659 2.2 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 836 859 0.46 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 351 386 0.0034 T 28-03-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat WM46_RS15775 a2459cd5e5a8b2be422becbd38a7d3fd 3629 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 64 163 2.5E-18 T 28-03-2018 IPR008638 Filamentous haemagglutinin, N-terminal WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 164 1.7E-15 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 Gene3D G3DSA:3.30.1330.10 31 161 5.4E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 335 1.9E-154 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 SUPERFAMILY SSF55326 7 170 2.09E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 Gene3D G3DSA:3.90.650.10 171 345 3.5E-63 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 339 1.1E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 SUPERFAMILY SSF56042 171 342 1.79E-64 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS00775 4f24afb62e56a0abcab45edff7be60a5 345 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 344 47.262 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 WM46_RS21455 ef84d686b5f5207d55fdda4242df7015 280 SUPERFAMILY SSF51366 86 261 1.73E-20 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS21455 ef84d686b5f5207d55fdda4242df7015 280 SUPERFAMILY SSF51366 37 55 1.73E-20 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS21455 ef84d686b5f5207d55fdda4242df7015 280 Gene3D G3DSA:3.20.20.70 6 163 1.9E-9 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS21455 ef84d686b5f5207d55fdda4242df7015 280 Gene3D G3DSA:3.20.20.70 164 263 5.4E-13 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS25475 fea520333ce853e950e0259676743810 321 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 43 311 8.3E-132 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 WM46_RS25475 fea520333ce853e950e0259676743810 321 Gene3D G3DSA:3.40.50.10490 2 195 8.7E-45 T 28-03-2018 WM46_RS25475 fea520333ce853e950e0259676743810 321 Gene3D G3DSA:3.10.580.10 196 318 2.4E-18 T 28-03-2018 WM46_RS25475 fea520333ce853e950e0259676743810 321 PIRSF PIRSF004692 1 321 1.6E-120 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 WM46_RS25475 fea520333ce853e950e0259676743810 321 SUPERFAMILY SSF54631 261 317 9.89E-9 T 28-03-2018 WM46_RS25475 fea520333ce853e950e0259676743810 321 Pfam PF00571 CBS domain 267 316 1.2E-4 T 28-03-2018 IPR000644 CBS domain WM46_RS25475 fea520333ce853e950e0259676743810 321 Pfam PF01380 SIS domain 39 169 5.2E-29 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS25475 fea520333ce853e950e0259676743810 321 SUPERFAMILY SSF53697 10 255 1.56E-51 T 28-03-2018 WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 Pfam PF00905 Penicillin binding protein transpeptidase domain 272 609 3.1E-90 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 19 612 1.0E-237 T 28-03-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0016020 WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 Gene3D G3DSA:3.90.1310.10 33 249 8.8E-54 T 28-03-2018 WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 Gene3D G3DSA:3.40.710.10 250 618 4.9E-82 T 28-03-2018 WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 SUPERFAMILY SSF56601 254 611 1.27E-91 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 SUPERFAMILY SSF56519 56 253 1.26E-53 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM46_RS11390 b59dfcd2935baa3a154492ee112fd0bd 633 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 239 6.3E-45 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 Gene3D G3DSA:3.40.1160.10 2 301 1.7E-42 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 TIGRFAM TIGR00746 arcC: carbamate kinase 3 300 6.4E-109 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 Pfam PF00696 Amino acid kinase family 3 278 4.8E-25 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PIRSF PIRSF000723 1 301 8.8E-105 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 SUPERFAMILY SSF53633 3 299 2.62E-66 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 104 123 7.5E-53 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 152 171 7.5E-53 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 205 220 7.5E-53 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 73 91 7.5E-53 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 175 193 7.5E-53 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 7.5E-53 T 28-03-2018 WM46_RS14925 715c11755b6821b465eb9efb246ec05d 301 PRINTS PR01469 Bacterial carbamate kinase signature 256 271 7.5E-53 T 28-03-2018 WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 SUPERFAMILY SSF52922 176 312 3.14E-28 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 Gene3D G3DSA:3.40.50.970 3 180 6.0E-28 T 28-03-2018 WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 Pfam PF02779 Transketolase, pyrimidine binding domain 13 168 8.9E-16 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 Gene3D G3DSA:3.40.50.920 181 315 3.4E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 SMART SM00861 9 170 1.0E-24 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 SUPERFAMILY SSF52518 5 177 4.71E-34 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS11680 59fd16f477790b27fef05d2f2ddacef4 315 Pfam PF02780 Transketolase, C-terminal domain 181 285 2.7E-23 T 28-03-2018 IPR033248 Transketolase, C-terminal domain WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 Pfam PF03466 LysR substrate binding domain 116 316 1.1E-16 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 Gene3D G3DSA:3.40.190.10 204 285 1.0E-9 T 28-03-2018 WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 Gene3D G3DSA:3.40.190.10 117 203 3.7E-10 T 28-03-2018 WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 SUPERFAMILY SSF46785 26 107 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 Gene3D G3DSA:1.10.10.10 24 108 3.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 SUPERFAMILY SSF53850 116 315 5.97E-24 T 28-03-2018 WM46_RS11420 0b9dc7f7d4127c945407c42c6139497b 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 31 89 1.8E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS04695 60b60aa9a60b97b2e7696921b8eaa08c 485 SUPERFAMILY SSF53448 10 205 2.63E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS04695 60b60aa9a60b97b2e7696921b8eaa08c 485 Gene3D G3DSA:3.90.550.10 10 256 1.7E-9 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 Pfam PF00797 N-acetyltransferase 22 255 2.9E-82 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 1.2E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 151 170 1.2E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 1.2E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 1.2E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 PRINTS PR01543 Arylamine N-acetyltransferase signature 101 126 1.2E-9 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 Gene3D G3DSA:3.30.2140.10 152 268 4.0E-14 T 28-03-2018 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 SUPERFAMILY SSF54001 2 267 3.92E-84 T 28-03-2018 WM46_RS06715 b10479fee0c7d779182c1917c6b46af1 281 Gene3D G3DSA:3.30.2140.10 2 151 3.4E-39 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 Gene3D G3DSA:1.20.200.10 103 372 7.1E-77 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00145 Argininosuccinate lyase family signature 97 119 5.9E-10 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00145 Argininosuccinate lyase family signature 273 289 5.9E-10 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00145 Argininosuccinate lyase family signature 228 252 5.9E-10 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00145 Argininosuccinate lyase family signature 138 158 5.9E-10 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 SMART SM00998 361 440 5.1E-24 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 6.1E-21 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 6.1E-21 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00149 Fumarate lyase superfamily signature 273 289 6.1E-21 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 PRINTS PR00149 Fumarate lyase superfamily signature 228 255 6.1E-21 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 Gene3D G3DSA:1.10.40.30 373 440 1.8E-20 T 28-03-2018 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 SUPERFAMILY SSF48557 13 446 1.1E-109 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 ProSitePatterns PS00163 Fumarate lyases signature. 273 282 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 439 3.3E-16 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 8 345 6.7E-120 T 28-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 Gene3D G3DSA:1.10.275.10 1 102 6.3E-15 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS06195 7c2a88ca3f22cbe297c379f990788204 454 Pfam PF00206 Lyase 13 293 1.1E-52 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.9E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 SUPERFAMILY SSF53850 94 293 1.81E-32 T 28-03-2018 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 Gene3D G3DSA:3.40.190.10 94 182 7.9E-17 T 28-03-2018 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 Pfam PF03466 LysR substrate binding domain 93 293 3.7E-39 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 SUPERFAMILY SSF46785 7 92 1.43E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 Gene3D G3DSA:3.40.190.10 183 271 1.6E-20 T 28-03-2018 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 6.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 6.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 6.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01190 235b5720fb7afdaf4b615b75510208f9 294 Gene3D G3DSA:1.10.10.10 1 92 4.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1563 1661 5.1E-5 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2348 2446 3.6E-8 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2791 2895 0.079 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1003 1101 0.026 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2121 2223 0.059 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1339 1438 0.11 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 891 990 7.5E-8 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2458 2558 0.009 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1674 1773 0.21 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1898 1997 0.0027 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2232 2334 0.056 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1115 1214 0.035 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1786 1885 0.0017 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 779 878 0.025 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2010 2107 0.0066 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1227 1326 6.8E-6 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 667 754 0.013 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2680 2779 0.068 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 1451 1550 7.3E-4 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00634 2571 2670 0.017 T 28-03-2018 IPR003344 Big-1 (bacterial Ig-like domain 1) domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1227 1329 9.68E-15 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1116 1218 1.12E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1783 1891 2.5E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2456 2565 3.6E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1337 1444 9.8E-20 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2231 2341 1.9E-19 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1225 1332 1.1E-24 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 776 884 2.8E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1671 1779 9.4E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 664 772 2.2E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1000 1108 1.6E-20 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1448 1556 2.4E-23 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1897 2004 7.1E-21 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2119 2226 7.2E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1112 1219 3.4E-22 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2348 2452 5.2E-24 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2788 2900 2.1E-11 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2007 2115 3.9E-21 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2569 2676 3.5E-19 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 889 995 8.0E-23 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 1561 1667 2.6E-24 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF09134 Invasin, domain 3 2682 2785 2.7E-15 T 28-03-2018 IPR015217 Invasin, domain 3 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2231 2330 2.25E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Pfam PF11924 Inverse autotransporter, beta-domain 150 422 8.6E-108 T 28-03-2018 IPR024519 Inverse autotransporter, beta-domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1671 1775 2.88E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:3.10.350.10 67 144 2.6E-8 T 28-03-2018 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2785 2897 7.32E-11 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1002 1100 9.16E-13 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2458 2560 2.62E-11 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2017 2106 4.45E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1562 1664 2.88E-14 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:3.10.100.10 2994 3090 2.2E-6 T 28-03-2018 IPR016186 C-type lectin-like/link domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 PRINTS PR01369 Intimin signature 371 390 4.1E-8 T 28-03-2018 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 PRINTS PR01369 Intimin signature 275 290 4.1E-8 T 28-03-2018 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 PRINTS PR01369 Intimin signature 303 322 4.1E-8 T 28-03-2018 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 PRINTS PR01369 Intimin signature 458 470 4.1E-8 T 28-03-2018 IPR003535 Intimin/invasin bacterial adhesion mediator protein GO:0007155 WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 891 992 8.89E-14 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1336 1435 1.36E-11 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SMART SM00257 73 121 3.6E-5 T 28-03-2018 IPR018392 LysM domain WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 778 881 7.85E-14 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2571 2673 1.23E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1384 1495 1.6E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1611 1717 2.8E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 422 595 3.7E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1271 1383 1.8E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1942 2051 2.4E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2054 2164 4.3E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 596 712 1.3E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1155 1270 7.1E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 822 937 8.4E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2165 2275 3.0E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2724 2828 2.0E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1048 1154 1.7E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 713 821 7.6E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2616 2723 4.7E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1832 1941 4.5E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1496 1610 4.8E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 938 1047 3.1E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 1718 1831 4.8E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2502 2615 1.2E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2392 2501 8.5E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 Gene3D G3DSA:2.60.120.260 2276 2391 1.2E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2905 2988 1.92E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1895 2000 1.07E-13 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 662 769 3.66E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1449 1554 3.14E-13 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 1784 1889 1.26E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2348 2441 6.54E-15 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2683 2783 2.15E-10 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS07670 c22b4e50c8a14c04f542248503aa044e 3093 SUPERFAMILY SSF49373 2121 2224 1.26E-12 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Pfam PF00271 Helicase conserved C-terminal domain 435 544 8.2E-18 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 5 666 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Pfam PF04851 Type III restriction enzyme, res subunit 13 119 2.2E-9 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Gene3D G3DSA:4.10.860.10 611 673 2.4E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 SMART SM00487 9 425 2.8E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 SMART SM00490 460 546 4.7E-20 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 SUPERFAMILY SSF52540 3 415 1.05E-138 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Gene3D G3DSA:3.40.50.300 415 589 4.1E-33 T 28-03-2018 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Gene3D G3DSA:3.40.50.300 10 413 8.4E-34 T 28-03-2018 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 SUPERFAMILY SSF46600 626 669 4.05E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 668 44.377 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Pfam PF12344 Ultra-violet resistance protein B 552 593 7.2E-22 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 Pfam PF02151 UvrB/uvrC motif 634 667 7.8E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 SUPERFAMILY SSF52540 459 581 5.21E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10570 58dcd7ebaac83921e636eb5a8dea77a1 673 SUPERFAMILY SSF52540 37 82 5.21E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13635 1fa48fbff0ae35b03d006f2e5da299a1 390 Gene3D G3DSA:1.10.150.130 86 200 8.7E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS13635 1fa48fbff0ae35b03d006f2e5da299a1 390 Pfam PF13356 Arm DNA-binding domain 3 86 6.6E-20 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS13635 1fa48fbff0ae35b03d006f2e5da299a1 390 Gene3D G3DSA:1.10.443.10 201 384 3.5E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS13635 1fa48fbff0ae35b03d006f2e5da299a1 390 SUPERFAMILY SSF56349 96 378 2.41E-58 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS13635 1fa48fbff0ae35b03d006f2e5da299a1 390 Pfam PF00589 Phage integrase family 204 368 7.9E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 95 138 2.0E-18 T 28-03-2018 WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 66 1.0E-27 T 28-03-2018 WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 Pfam PF00936 BMC domain 4 76 1.5E-22 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 Pfam PF00936 BMC domain 96 173 9.1E-22 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 PIRSF PIRSF034834 1 183 5.4E-82 T 28-03-2018 IPR011238 Polyhedral organelle shell protein PduT WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 SMART SM00877 3 77 3.2E-28 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 SMART SM00877 95 173 1.0E-27 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 SUPERFAMILY SSF143414 95 181 6.28E-23 T 28-03-2018 WM46_RS03445 00ccbc69a50bdee7466286c857c5d4c7 184 SUPERFAMILY SSF143414 3 93 1.83E-25 T 28-03-2018 WM46_RS22590 9a1651bbe76a9b1a20c4c960e42a78de 296 SUPERFAMILY SSF56349 18 270 5.49E-12 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS22590 9a1651bbe76a9b1a20c4c960e42a78de 296 Gene3D G3DSA:1.10.443.10 127 296 3.0E-9 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS22590 9a1651bbe76a9b1a20c4c960e42a78de 296 Pfam PF12835 Integrase 104 251 4.1E-59 T 28-03-2018 IPR024456 Integrase catalytic domain, putative WM46_RS22590 9a1651bbe76a9b1a20c4c960e42a78de 296 Gene3D G3DSA:1.10.150.130 3 126 7.0E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS22590 9a1651bbe76a9b1a20c4c960e42a78de 296 Pfam PF12834 Phage integrase, N-terminal 1 90 2.4E-35 T 28-03-2018 IPR024457 Putative integrase, N-terminal WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 Gene3D G3DSA:3.30.70.20 10 47 5.5E-8 T 28-03-2018 WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 Gene3D G3DSA:3.30.70.20 80 165 6.9E-6 T 28-03-2018 WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 Gene3D G3DSA:3.30.70.20 48 79 4.6E-13 T 28-03-2018 WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 SUPERFAMILY SSF54862 18 115 1.42E-22 T 28-03-2018 WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 Pfam PF12838 4Fe-4S dicluster domain 39 89 2.1E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS25410 ff361c2f4e083cda20a4c2fe111bf682 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS20910 28192463e013d07360796ccd33bbf0f5 296 Pfam PF02219 Methylenetetrahydrofolate reductase 16 291 6.2E-109 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 WM46_RS20910 28192463e013d07360796ccd33bbf0f5 296 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 290 1.8E-107 T 28-03-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 WM46_RS20910 28192463e013d07360796ccd33bbf0f5 296 Gene3D G3DSA:3.20.20.220 1 296 6.8E-102 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like WM46_RS20910 28192463e013d07360796ccd33bbf0f5 296 SUPERFAMILY SSF51730 22 294 1.41E-98 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 SMART SM00382 28 180 1.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 Pfam PF00158 Sigma-54 interaction domain 9 170 4.7E-62 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 SUPERFAMILY SSF52540 9 247 1.87E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 222 231 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 8 322 5.0E-161 T 28-03-2018 IPR014317 Transcription activator PspF WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 94 109 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 305 324 1.4E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 288 305 1.4E-7 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 Pfam PF02954 Bacterial regulatory protein, Fis family 284 321 9.8E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 Gene3D G3DSA:1.10.10.60 268 324 3.5E-11 T 28-03-2018 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 Gene3D G3DSA:3.40.50.300 1 179 6.3E-29 T 28-03-2018 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 Gene3D G3DSA:1.10.8.60 180 258 3.1E-17 T 28-03-2018 WM46_RS06070 28e4642d480bef0ca95ce2d890db4995 324 SUPERFAMILY SSF46689 222 324 5.38E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS24985 da49c1c7d6f90b99d73755bc056d684f 366 Gene3D G3DSA:3.40.50.150 176 357 4.0E-22 T 28-03-2018 WM46_RS24985 da49c1c7d6f90b99d73755bc056d684f 366 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 355 85.953 T 28-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 WM46_RS24985 da49c1c7d6f90b99d73755bc056d684f 366 Pfam PF01728 FtsJ-like methyltransferase 186 279 1.9E-8 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 WM46_RS24985 da49c1c7d6f90b99d73755bc056d684f 366 PIRSF PIRSF028774 1 360 6.0E-189 T 28-03-2018 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 WM46_RS24985 da49c1c7d6f90b99d73755bc056d684f 366 SUPERFAMILY SSF53335 184 296 1.06E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 Pfam PF00871 Acetokinase family 7 386 1.1E-161 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 SUPERFAMILY SSF53067 153 392 2.73E-85 T 28-03-2018 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 199 216 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 TIGRFAM TIGR00016 ackA: acetate kinase 4 392 3.6E-167 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 Gene3D G3DSA:3.30.420.40 6 191 8.4E-64 T 28-03-2018 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 Hamap MF_01881 Propionate kinase [tdcD]. 1 402 74.703 T 28-03-2018 IPR024917 Propionate kinase KEGG: 00640+2.7.2.15|MetaCyc: PWY-5437|MetaCyc: PWY-7013 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 SUPERFAMILY SSF53067 5 190 2.23E-64 T 28-03-2018 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PRINTS PR00471 Acetate kinase family signature 199 220 1.2E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PRINTS PR00471 Acetate kinase family signature 296 309 1.2E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PRINTS PR00471 Acetate kinase family signature 374 386 1.2E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PRINTS PR00471 Acetate kinase family signature 318 334 1.2E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PRINTS PR00471 Acetate kinase family signature 169 182 1.2E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PRINTS PR00471 Acetate kinase family signature 7 18 1.2E-46 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 Gene3D G3DSA:3.30.420.40 193 401 1.1E-74 T 28-03-2018 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 7 18 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 Hamap MF_00020 Acetate kinase [ackA]. 1 396 161.882 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS16490 ac6946e7ec0ef4174e99cb472ca4e49e 402 PIRSF PIRSF000722 3 396 5.0E-134 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 SUPERFAMILY SSF74650 5 248 2.17E-49 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 SUPERFAMILY SSF51445 252 599 1.24E-71 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Gene3D G3DSA:3.20.20.80 249 621 9.8E-104 T 28-03-2018 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Gene3D G3DSA:2.60.40.1180 622 684 9.1E-23 T 28-03-2018 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Pfam PF13802 Galactose mutarotase-like 151 218 1.6E-23 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 SUPERFAMILY SSF51011 602 683 3.96E-18 T 28-03-2018 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Gene3D G3DSA:2.60.40.1760 13 248 2.5E-47 T 28-03-2018 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Pfam PF17137 Domain of unknown function (DUF5110) 705 771 1.4E-7 T 28-03-2018 IPR033403 Domain of unknown function DUF5110 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Pfam PF01055 Glycosyl hydrolases family 31 243 686 4.3E-116 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 WM46_RS10340 df65309ebb8be5dcc43ae07ad6dfc85b 792 Gene3D G3DSA:2.60.40.1180 685 788 1.2E-10 T 28-03-2018 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 Gene3D G3DSA:3.40.228.10 1 265 6.7E-70 T 28-03-2018 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 715 742 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 Gene3D G3DSA:3.40.50.740 266 449 7.3E-29 T 28-03-2018 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 Pfam PF01568 Molydopterin dinucleotide binding domain 681 796 2.7E-15 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 Gene3D G3DSA:3.40.228.10 465 627 3.5E-14 T 28-03-2018 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 Gene3D G3DSA:2.40.40.20 628 803 2.1E-40 T 28-03-2018 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 Pfam PF00384 Molybdopterin oxidoreductase 2 377 1.7E-21 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 SUPERFAMILY SSF50692 641 803 3.39E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 SUPERFAMILY SSF53706 1 638 7.2E-233 T 28-03-2018 WM46_RS06785 4d2077ef2ac6f49943be18525428513a 803 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 802 0.0 T 28-03-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 73 93 6.5E-42 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 13 30 6.5E-42 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 97 119 6.5E-42 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 123 141 6.5E-42 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 Gene3D G3DSA:3.10.420.10 1 153 1.6E-56 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 Hamap MF_00821 Protein-export protein SecB [secB]. 1 145 33.593 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 Pfam PF02556 Preprotein translocase subunit SecB 5 144 6.1E-58 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 SUPERFAMILY SSF54611 2 141 8.28E-54 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS20280 f5f817116ad388d71f5f67355b50c351 155 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 5 147 5.1E-71 T 28-03-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 65 85 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 3 22 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 128 149 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 44 64 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 23 43 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 86 106 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PRINTS PR00601 Bacterioferritin signature 107 127 1.6E-77 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 Pfam PF00210 Ferritin-like domain 8 143 7.9E-39 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 PIRSF PIRSF002560 1 157 2.2E-71 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 SUPERFAMILY SSF47240 1 154 1.06E-53 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 1.1E-81 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 WM46_RS17560 cddc17cf573f66f8bf5615efb5abbac5 158 Gene3D G3DSA:1.20.1260.10 2 150 2.2E-39 T 28-03-2018 IPR012347 Ferritin-related WM46_RS07520 bee3696c1492540636358aaf63ea101e 285 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 43 230 1.0E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS07520 bee3696c1492540636358aaf63ea101e 285 Gene3D G3DSA:2.40.50.100 142 281 2.0E-6 T 28-03-2018 WM46_RS07520 bee3696c1492540636358aaf63ea101e 285 SUPERFAMILY SSF111369 42 218 6.93E-27 T 28-03-2018 WM46_RS07520 bee3696c1492540636358aaf63ea101e 285 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 230 1.1E-38 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS07520 bee3696c1492540636358aaf63ea101e 285 Gene3D G3DSA:2.40.50.100 43 116 2.1E-17 T 28-03-2018 WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 SMART SM00382 209 389 7.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 288 303 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 400 492 4.1E-30 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 SUPERFAMILY SSF52540 189 500 4.48E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 SUPERFAMILY SSF54211 11 169 7.21E-29 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 1.8E-43 T 28-03-2018 WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 492 7.8E-233 T 28-03-2018 IPR004482 Mg chelatase-related protein WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 Gene3D G3DSA:3.40.50.300 186 452 4.5E-23 T 28-03-2018 WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 189 386 3.7E-88 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain WM46_RS19360 2de2b7a391aabb02c510f671dd0745b7 506 Gene3D G3DSA:3.30.230.10 2 185 2.0E-35 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS15915 680b623049d63b5b6efb4e075e057471 113 PIRSF PIRSF004761 1 113 3.6E-38 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS15915 680b623049d63b5b6efb4e075e057471 113 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 113 24.72 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS15915 680b623049d63b5b6efb4e075e057471 113 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 28-03-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site WM46_RS15915 680b623049d63b5b6efb4e075e057471 113 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 3.2E-33 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS15915 680b623049d63b5b6efb4e075e057471 113 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 113 1.1E-44 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 6.5E-9 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 6.5E-9 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 6.5E-9 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 6.5E-9 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 6.5E-9 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 Gene3D G3DSA:1.20.1250.20 12 197 9.0E-28 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 Gene3D G3DSA:1.20.1250.20 256 465 1.6E-21 T 28-03-2018 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 432 1.5E-77 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 Pfam PF07690 Major Facilitator Superfamily 17 406 1.8E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 SUPERFAMILY SSF103473 14 195 2.22E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19410 a3c8a90618b9e223550a71c985d1a360 475 SUPERFAMILY SSF103473 245 453 2.22E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04350 bf45a270725375665b34de065ccf31a8 603 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 505 516 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS04350 bf45a270725375665b34de065ccf31a8 603 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS04350 bf45a270725375665b34de065ccf31a8 603 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 601 0.0 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 WM46_RS04350 bf45a270725375665b34de065ccf31a8 603 SUPERFAMILY SSF52016 419 600 1.33E-57 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS04350 bf45a270725375665b34de065ccf31a8 603 SUPERFAMILY SSF143975 1 418 2.88E-146 T 28-03-2018 WM46_RS04350 bf45a270725375665b34de065ccf31a8 603 Pfam PF00920 Dehydratase family 66 598 7.2E-159 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PIRSF PIRSF000350 2 463 4.3E-70 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 SUPERFAMILY SSF55424 345 463 1.05E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 2 466 69.997 T 28-03-2018 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 346 457 2.5E-30 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 Gene3D G3DSA:3.40.50.720 171 336 2.6E-28 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 1.4E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 Gene3D G3DSA:3.50.50.60 3 164 1.9E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 Gene3D G3DSA:3.30.390.30 337 463 6.7E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 SUPERFAMILY SSF51905 2 335 1.83E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 363 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 1.6E-49 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.2E-25 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 1.2E-25 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 1.2E-25 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.2E-25 T 28-03-2018 WM46_RS21055 3bdab4c18eb074f9a689f1ab379986be 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 1.2E-25 T 28-03-2018 WM46_RS09665 1127e2eb20a4b0401ee615edbc75b9f9 55 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 55 4.0E-25 T 28-03-2018 IPR007040 Ribosome modulation factor WM46_RS09665 1127e2eb20a4b0401ee615edbc75b9f9 55 Gene3D G3DSA:1.10.10.620 3 53 3.2E-26 T 28-03-2018 WM46_RS09665 1127e2eb20a4b0401ee615edbc75b9f9 55 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 31.824 T 28-03-2018 IPR007040 Ribosome modulation factor WM46_RS09665 1127e2eb20a4b0401ee615edbc75b9f9 55 Pfam PF04957 Ribosome modulation factor 1 52 2.6E-30 T 28-03-2018 IPR007040 Ribosome modulation factor WM46_RS10655 c56396e4a78f5e5871c7213addc87659 257 Gene3D G3DSA:3.40.190.10 122 218 1.1E-32 T 28-03-2018 WM46_RS10655 c56396e4a78f5e5871c7213addc87659 257 Gene3D G3DSA:3.40.190.10 26 121 2.5E-17 T 28-03-2018 WM46_RS10655 c56396e4a78f5e5871c7213addc87659 257 PIRSF PIRSF004846 1 257 3.9E-84 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 WM46_RS10655 c56396e4a78f5e5871c7213addc87659 257 SUPERFAMILY SSF53850 28 255 3.16E-70 T 28-03-2018 WM46_RS10655 c56396e4a78f5e5871c7213addc87659 257 Pfam PF13531 Bacterial extracellular solute-binding protein 29 254 2.5E-50 T 28-03-2018 WM46_RS10655 c56396e4a78f5e5871c7213addc87659 257 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 34 253 5.0E-87 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 WM46_RS01585 9b319d837489c8087a63258d77524931 422 Gene3D G3DSA:3.90.190.20 288 419 4.0E-30 T 28-03-2018 WM46_RS01585 9b319d837489c8087a63258d77524931 422 Pfam PF02875 Mur ligase family, glutamate ligase domain 287 346 1.3E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 144 159 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 Pfam PF08245 Mur ligase middle domain 54 195 1.0E-9 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 SUPERFAMILY SSF53623 13 284 5.04E-88 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 SUPERFAMILY SSF53244 286 413 5.23E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 PIRSF PIRSF001563 6 418 2.9E-106 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 52 75 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 Gene3D G3DSA:3.40.1190.10 1 287 2.3E-78 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS01585 9b319d837489c8087a63258d77524931 422 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 413 3.4E-112 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 304 3.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 SMART SM00387 349 461 1.6E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 SUPERFAMILY SSF55874 293 459 3.54E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 SMART SM00388 240 304 5.0E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 Gene3D G3DSA:1.10.287.130 245 299 1.5E-13 T 28-03-2018 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 2.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 2.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 2.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 2.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 SUPERFAMILY SSF158472 188 236 4.97E-9 T 28-03-2018 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 460 1.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 Gene3D G3DSA:3.30.450.20 35 244 0.002 T 28-03-2018 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 Gene3D G3DSA:3.30.565.10 308 466 1.8E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 SUPERFAMILY SSF47384 223 304 7.06E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 SMART SM00304 187 239 2.1E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS02725 a720ea63e65015bbd69f1625b1e7057c 467 Pfam PF00672 HAMP domain 188 235 2.1E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS03460 c4dac64e5138733cb2aabb9e8c09ca44 461 SUPERFAMILY SSF53720 32 452 6.02E-60 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS03460 c4dac64e5138733cb2aabb9e8c09ca44 461 PIRSF PIRSF036410 1 461 7.7E-209 T 28-03-2018 IPR012408 Acetaldehyde/propionaldehyde dehydrogenase, EutE/PduP-related WM46_RS03460 c4dac64e5138733cb2aabb9e8c09ca44 461 Gene3D G3DSA:3.40.309.10 252 422 2.9E-22 T 28-03-2018 WM46_RS03460 c4dac64e5138733cb2aabb9e8c09ca44 461 Gene3D G3DSA:3.40.605.10 30 251 3.4E-34 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS03460 c4dac64e5138733cb2aabb9e8c09ca44 461 Pfam PF00171 Aldehyde dehydrogenase family 33 290 7.3E-26 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 SUPERFAMILY SSF54534 96 241 3.34E-37 T 28-03-2018 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 SUPERFAMILY SSF109998 248 429 1.27E-47 T 28-03-2018 IPR027304 Trigger factor/SurA domain WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 TIGRFAM TIGR00115 tig: trigger factor 13 412 4.7E-143 T 28-03-2018 IPR005215 Trigger factor GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 SUPERFAMILY SSF102735 1 131 5.75E-39 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 412 8.8E-41 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 Gene3D G3DSA:1.10.3120.10 211 389 1.7E-47 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 Hamap MF_00303 Trigger factor [tig]. 1 418 22.061 T 28-03-2018 IPR005215 Trigger factor GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 PIRSF PIRSF003095 1 432 5.2E-131 T 28-03-2018 IPR005215 Trigger factor GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 Gene3D G3DSA:3.30.70.1050 1 118 2.3E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 2.5E-41 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 WM46_RS12635 5fb6fa3c73440e183bf59aaff3e45bbb 432 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 236 4.9E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 Gene3D G3DSA:2.30.42.10 221 309 7.4E-19 T 28-03-2018 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 SUPERFAMILY SSF50156 195 290 1.58E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 450 8.7E-172 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 SUPERFAMILY SSF50156 86 187 1.31E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 209 277 8.0E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 Gene3D G3DSA:2.30.42.10 126 220 4.6E-12 T 28-03-2018 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 SMART SM00228 211 280 7.9E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 SMART SM00228 115 186 0.032 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS13940 3e3f61864b2f3273dc4c29358a33a7ee 450 Pfam PF02163 Peptidase family M50 10 438 1.3E-87 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 WM46_RS05455 794cda4e472cac7a56d236381fac69f4 283 SUPERFAMILY SSF55469 31 282 2.49E-52 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS05455 794cda4e472cac7a56d236381fac69f4 283 Pfam PF00881 Nitroreductase family 37 196 4.1E-20 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 WM46_RS05455 794cda4e472cac7a56d236381fac69f4 283 PIRSF PIRSF005426 28 283 4.0E-70 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 WM46_RS05455 794cda4e472cac7a56d236381fac69f4 283 Gene3D G3DSA:3.40.109.10 29 283 4.5E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 SUPERFAMILY SSF47323 391 548 8.41E-47 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Gene3D G3DSA:2.170.220.10 181 248 1.4E-15 T 28-03-2018 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Gene3D G3DSA:2.40.50.140 567 677 1.1E-24 T 28-03-2018 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 543 677 3.3E-47 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 SUPERFAMILY SSF50249 570 676 3.92E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Gene3D G3DSA:3.40.50.620 249 372 9.6E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 536 1.6E-208 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Gene3D G3DSA:2.20.28.20 142 175 2.0E-15 T 28-03-2018 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Gene3D G3DSA:1.10.730.10 374 537 1.3E-36 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 SUPERFAMILY SSF52374 176 388 1.41E-106 T 28-03-2018 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 SUPERFAMILY SSF52374 6 141 1.41E-106 T 28-03-2018 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Pfam PF01588 Putative tRNA binding domain 581 674 5.6E-22 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Gene3D G3DSA:3.40.50.620 5 133 4.6E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 292 307 7.1E-26 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 7.1E-26 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 7.1E-26 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 7.1E-26 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 7.1E-26 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 385 396 7.1E-26 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Pfam PF09334 tRNA synthetases class I (M) 8 397 3.7E-165 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 SUPERFAMILY SSF57770 142 176 1.15E-12 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS02625 0459cec8fd707761c70908912e61c1ee 677 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 546 41.878 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS06650 31894ddcd33983e1ee44d58f13b5f620 353 Gene3D G3DSA:2.130.10.10 31 353 1.8E-49 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 WM46_RS06650 31894ddcd33983e1ee44d58f13b5f620 353 SUPERFAMILY SSF51004 39 337 1.31E-37 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain WM46_RS18040 0655fb238143a2b9d84a7f3311c0dbdd 197 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 191 2.7E-30 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 WM46_RS18040 0655fb238143a2b9d84a7f3311c0dbdd 197 Pfam PF01914 MarC family integral membrane protein 1 195 3.2E-64 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 Gene3D G3DSA:1.25.60.10 37 154 1.3E-16 T 28-03-2018 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 Gene3D G3DSA:1.10.357.20 305 478 1.1E-33 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 Gene3D G3DSA:3.10.580.10 155 290 1.9E-16 T 28-03-2018 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 Pfam PF00571 CBS domain 229 283 2.6E-6 T 28-03-2018 IPR000644 CBS domain WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 Pfam PF01769 Divalent cation transporter 349 470 2.7E-23 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 SMART SM00924 62 165 6.2E-30 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 TIGRFAM TIGR00400 mgtE: magnesium transporter 53 477 1.6E-74 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 Pfam PF03448 MgtE intracellular N domain 63 163 4.8E-24 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 SUPERFAMILY SSF161093 306 477 6.8E-48 T 28-03-2018 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 SUPERFAMILY SSF54631 164 303 8.84E-26 T 28-03-2018 WM46_RS02110 034e9bd509adf305cab935e57a6e8e87 478 SUPERFAMILY SSF158791 50 161 1.57E-23 T 28-03-2018 WM46_RS08395 36369d17cd02006c4ba20978eb5ce72c 393 TIGRFAM TIGR00896 CynX: cyanate transporter 14 367 1.9E-139 T 28-03-2018 IPR004747 Cyanate transport system protein GO:0016021 WM46_RS08395 36369d17cd02006c4ba20978eb5ce72c 393 Pfam PF07690 Major Facilitator Superfamily 22 348 3.6E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS08395 36369d17cd02006c4ba20978eb5ce72c 393 Gene3D G3DSA:1.20.1250.20 199 391 3.3E-20 T 28-03-2018 WM46_RS08395 36369d17cd02006c4ba20978eb5ce72c 393 Gene3D G3DSA:1.20.1250.20 10 198 6.4E-16 T 28-03-2018 WM46_RS08395 36369d17cd02006c4ba20978eb5ce72c 393 SUPERFAMILY SSF103473 8 387 2.88E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS17770 5a625b087f442d7cc0f4b705f829513e 429 SUPERFAMILY SSF110997 345 409 6.41E-7 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS17770 5a625b087f442d7cc0f4b705f829513e 429 Hamap MF_02021 Cell division protein DamX [damX]. 1 429 25.694 T 28-03-2018 IPR032899 Cell division protein DamX GO:0030428|GO:0032506 WM46_RS17770 5a625b087f442d7cc0f4b705f829513e 429 Gene3D G3DSA:3.30.70.1070 348 412 2.8E-4 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS17770 5a625b087f442d7cc0f4b705f829513e 429 Pfam PF05036 Sporulation related domain 346 418 2.5E-12 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 49.575 T 28-03-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 320 8.0E-141 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 PIRSF PIRSF006621 1 321 7.5E-100 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 Gene3D G3DSA:3.20.20.70 8 240 3.8E-55 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 Pfam PF01207 Dihydrouridine synthase (Dus) 14 318 8.2E-116 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 Gene3D G3DSA:1.10.1200.80 252 321 1.3E-21 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 WM46_RS17245 0f36a0cfc7a4f6f6a81a4e105e97b11d 321 SUPERFAMILY SSF51395 10 319 1.67E-86 T 28-03-2018 WM46_RS22930 dbacda9becc816ae71f5f641e75dfaa6 235 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 228 9.7E-57 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS22930 dbacda9becc816ae71f5f641e75dfaa6 235 TIGRFAM TIGR00035 asp_race: aspartate racemase 6 230 1.1E-46 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 WM46_RS22930 dbacda9becc816ae71f5f641e75dfaa6 235 SUPERFAMILY SSF53681 122 228 2.4E-20 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS22930 dbacda9becc816ae71f5f641e75dfaa6 235 Gene3D G3DSA:3.40.50.1860 121 217 1.3E-20 T 28-03-2018 WM46_RS22930 dbacda9becc816ae71f5f641e75dfaa6 235 SUPERFAMILY SSF53681 7 115 2.4E-31 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS22930 dbacda9becc816ae71f5f641e75dfaa6 235 Gene3D G3DSA:3.40.50.1860 5 120 1.7E-34 T 28-03-2018 WM46_RS23485 ffc89d61bb6a2560a1016b29622de4db 75 Gene3D G3DSA:3.40.930.10 2 75 1.9E-9 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS23485 ffc89d61bb6a2560a1016b29622de4db 75 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 73 3.3E-7 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS23485 ffc89d61bb6a2560a1016b29622de4db 75 SUPERFAMILY SSF55804 3 73 3.66E-11 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 SUPERFAMILY SSF52540 272 511 1.59E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 SMART SM00382 292 436 7.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 160 207 3.2E-6 T 28-03-2018 IPR000014 PAS domain WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 486 495 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Pfam PF02954 Bacterial regulatory protein, Fis family 548 587 4.8E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Gene3D G3DSA:3.40.50.300 271 458 7.9E-29 T 28-03-2018 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Pfam PF00158 Sigma-54 interaction domain 272 439 1.6E-67 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 SMART SM00091 160 225 2.2E-5 T 28-03-2018 IPR000014 PAS domain WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Gene3D G3DSA:3.30.450.20 163 270 1.2E-8 T 28-03-2018 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Gene3D G3DSA:1.10.10.60 553 589 5.3E-15 T 28-03-2018 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 SUPERFAMILY SSF46689 542 589 5.12E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 SUPERFAMILY SSF55785 162 221 1.1E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Gene3D G3DSA:1.10.8.60 459 552 5.3E-21 T 28-03-2018 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Gene3D G3DSA:3.30.450.40 7 162 4.2E-4 T 28-03-2018 IPR029016 GAF domain-like WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 Pfam PF00989 PAS fold 162 205 2.6E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS24370 4012aa75e6ba9e1d52e08f0e3a9b238c 592 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 296 309 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS11620 bbd9c53ed1b086b1ff25b6b529308a3d 377 Gene3D G3DSA:3.30.1890.10 52 213 3.1E-38 T 28-03-2018 WM46_RS11620 bbd9c53ed1b086b1ff25b6b529308a3d 377 SUPERFAMILY SSF160355 65 329 3.4E-80 T 28-03-2018 WM46_RS11620 bbd9c53ed1b086b1ff25b6b529308a3d 377 Pfam PF02706 Chain length determinant protein 25 122 1.2E-20 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 WM46_RS11620 bbd9c53ed1b086b1ff25b6b529308a3d 377 Gene3D G3DSA:1.10.287.210 214 312 2.0E-28 T 28-03-2018 WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 SMART SM00304 176 228 5.0E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 35 124 4.1E-10 T 28-03-2018 IPR029095 NarX-like, N-terminal WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 SMART SM00387 494 587 4.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 SUPERFAMILY SSF158472 178 226 3.79E-6 T 28-03-2018 WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 Gene3D G3DSA:3.30.565.10 454 587 4.3E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 497 583 1.8E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 Pfam PF07730 Histidine kinase 390 453 3.0E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 PIRSF PIRSF003167 1 597 1.7E-194 T 28-03-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 Gene3D G3DSA:3.30.450.40 212 331 7.7E-4 T 28-03-2018 IPR029016 GAF domain-like WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 SUPERFAMILY SSF55874 466 583 3.8E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS05615 62e946442dacc1391e8c1b0c8a9f2f7c 598 Pfam PF00672 HAMP domain 177 224 4.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 ProSitePatterns PS00194 Thioredoxin family active site. 111 129 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 Pfam PF13098 Thioredoxin-like domain 105 227 7.8E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 Gene3D G3DSA:3.10.450.70 19 79 1.6E-22 T 28-03-2018 WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 Gene3D G3DSA:3.40.30.10 93 237 3.8E-29 T 28-03-2018 WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 SUPERFAMILY SSF52833 87 233 9.89E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 Pfam PF10411 Disulfide bond isomerase protein N-terminus 27 76 1.4E-15 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal WM46_RS24265 5be4912d9ea275b71362c822d25788a4 237 SUPERFAMILY SSF54423 23 81 3.92E-18 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 254 1.5E-82 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 SUPERFAMILY SSF101790 271 361 3.92E-26 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Gene3D G3DSA:3.30.1360.120 136 231 1.3E-23 T 28-03-2018 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 359 1.1E-164 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 PIRSF PIRSF006487 1 363 1.7E-78 T 28-03-2018 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Gene3D G3DSA:2.40.30.110 277 364 6.5E-19 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Gene3D G3DSA:3.30.1360.120 2 135 1.5E-32 T 28-03-2018 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 SUPERFAMILY SSF103025 3 277 2.2E-89 T 28-03-2018 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 359 44.42 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 262 353 4.2E-17 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 WM46_RS24200 fe69ac84f0d390236fafcfb6f9b1b486 364 Gene3D G3DSA:4.10.1250.10 232 276 2.6E-16 T 28-03-2018 WM46_RS01360 7e330fd110ab41459152df9dd6fffdaa 306 PIRSF PIRSF026649 3 305 5.5E-91 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM46_RS01360 7e330fd110ab41459152df9dd6fffdaa 306 Hamap MF_01943 Lipid A biosynthesis palmitoleoyltransferase [lpxP]. 3 305 69.84 T 28-03-2018 IPR030857 Lipid A biosynthesis palmitoleoyltransferase, LpxP GO:0008951|GO:0009409|GO:0036104 KEGG: 00600+2.3.1.24 WM46_RS01360 7e330fd110ab41459152df9dd6fffdaa 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 296 3.3E-112 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM46_RS01360 7e330fd110ab41459152df9dd6fffdaa 306 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 5 305 5.1E-140 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 WM46_RS01360 7e330fd110ab41459152df9dd6fffdaa 306 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 305 49.619 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 SUPERFAMILY SSF48179 162 268 3.06E-37 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 Gene3D G3DSA:3.40.50.720 1 159 3.1E-34 T 28-03-2018 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 SUPERFAMILY SSF51735 3 159 4.3E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 26.973 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 PIRSF PIRSF000193 2 269 7.1E-98 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 1.1E-92 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 Gene3D G3DSA:1.10.3730.10 160 269 1.4E-43 T 28-03-2018 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 3.1E-24 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 WM46_RS12970 0368690d61445ddb2a9a3dc8a831236d 269 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 4.8E-38 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 109 136 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 361 379 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 252 271 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 320 345 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PRINTS PR00083 Histidinol dehydrogenase signature 230 251 7.4E-102 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 Gene3D G3DSA:3.40.50.1980 29 225 1.3E-86 T 28-03-2018 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 426 6.8E-160 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 PIRSF PIRSF000099 1 430 3.8E-171 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 Pfam PF00815 Histidinol dehydrogenase 28 427 1.1E-164 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 230 262 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 SUPERFAMILY SSF53720 6 429 1.75E-92 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 Gene3D G3DSA:3.40.50.1980 226 371 2.5E-70 T 28-03-2018 WM46_RS03035 46f6daa8a7a7e63d63bf124bf9a9ed00 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 427 41.15 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 SUPERFAMILY SSF52172 4 130 6.12E-26 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 Pfam PF00072 Response regulator receiver domain 10 120 1.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 SUPERFAMILY SSF46894 136 208 4.76E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 Gene3D G3DSA:1.10.10.10 143 209 1.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 6.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 1.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 1.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 1.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 SMART SM00421 146 203 6.8E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 Gene3D G3DSA:3.40.50.2300 1 142 5.1E-25 T 28-03-2018 WM46_RS24505 e5be2171653ea9506eac32b04967ccf1 209 SMART SM00448 7 119 4.9E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 333 5.2E-125 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 SUPERFAMILY SSF55347 154 308 4.11E-49 T 28-03-2018 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 149 165 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 Gene3D G3DSA:3.40.50.720 1 162 4.5E-44 T 28-03-2018 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 334 38.459 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 163 311 3.5E-18 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 Gene3D G3DSA:3.30.360.10 163 308 2.6E-49 T 28-03-2018 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 SMART SM00859 3 146 4.8E-54 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 146 2.6E-33 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS20995 491b1ac924f33afae9f64a511679ec3f 334 SUPERFAMILY SSF51735 1 172 1.16E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 SUPERFAMILY SSF69075 317 417 2.48E-26 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 418 30.719 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 Gene3D G3DSA:3.40.50.720 161 313 1.5E-23 T 28-03-2018 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 Gene3D G3DSA:1.10.1200.70 332 418 4.2E-22 T 28-03-2018 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 SUPERFAMILY SSF69742 1 158 6.93E-47 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 SUPERFAMILY SSF51735 162 315 1.82E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 2.0E-48 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 172 306 5.0E-49 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 418 1.3E-167 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 416 3.0E-23 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS05550 6442a6e188c3dd424614fbd073bd8cc0 418 PIRSF PIRSF000445 1 418 1.6E-153 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 WM46_RS13670 78e8475e58aeffef6ca5266dfa22ff8d 152 SUPERFAMILY SSF53271 4 145 3.54E-32 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS13670 78e8475e58aeffef6ca5266dfa22ff8d 152 Pfam PF00156 Phosphoribosyl transferase domain 12 145 3.2E-15 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM46_RS13670 78e8475e58aeffef6ca5266dfa22ff8d 152 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 1 152 40.438 T 28-03-2018 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22 WM46_RS13670 78e8475e58aeffef6ca5266dfa22ff8d 152 Gene3D G3DSA:3.40.50.2020 1 152 6.9E-27 T 28-03-2018 WM46_RS08875 aaca74cadd8d1da7629e109b8d2c3367 190 SUPERFAMILY SSF81342 5 182 1.1E-37 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM46_RS08875 aaca74cadd8d1da7629e109b8d2c3367 190 Pfam PF01292 Prokaryotic cytochrome b561 9 180 1.2E-27 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM46_RS08875 aaca74cadd8d1da7629e109b8d2c3367 190 Gene3D G3DSA:1.20.950.20 1 189 9.6E-35 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:2.40.40.20 1047 1237 1.6E-46 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Pfam PF01568 Molydopterin dinucleotide binding domain 1087 1199 1.7E-20 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:3.40.50.740 108 213 0.0027 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 776 793 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:3.40.50.740 647 789 7.6E-34 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Pfam PF00384 Molybdopterin oxidoreductase 108 831 6.4E-167 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 SMART SM00926 43 105 6.6E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:2.20.25.90 55 98 1.3E-28 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1234 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:3.30.2070.10 794 834 4.0E-5 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:3.40.228.10 225 646 5.0E-104 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 4 40 6.3E-16 T 28-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 SUPERFAMILY SSF50692 1082 1235 1.18E-46 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 Gene3D G3DSA:4.10.1200.10 1 26 9.0E-15 T 28-03-2018 WM46_RS06745 285a20612df8ed2d03cd2d9e8d1aaf19 1246 SUPERFAMILY SSF53706 5 1070 0.0 T 28-03-2018 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Gene3D G3DSA:2.40.50.140 49 116 6.0E-32 T 28-03-2018 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 SUPERFAMILY SSF68912 1 46 2.0E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 SMART SM00382 170 355 5.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 SUPERFAMILY SSF50249 48 125 9.0E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 4.3E-17 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 1.0E-222 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 SMART SM00357 52 118 9.6E-19 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Gene3D G3DSA:1.10.720.10 1 43 1.9E-13 T 28-03-2018 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.7E-32 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 252.259 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 8.1E-23 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 SMART SM00959 5 47 6.9E-18 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 Gene3D G3DSA:3.40.50.300 129 419 5.9E-58 T 28-03-2018 WM46_RS19260 ad1a8af67b9c891d8755099b984fd1ea 419 SUPERFAMILY SSF52540 90 371 1.22E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 8.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 8.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 8.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 180 0.0016 T 28-03-2018 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 SUPERFAMILY SSF51735 4 249 1.76E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 97 117 1.2E-65 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 162 185 1.2E-65 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 227 246 1.2E-65 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 201 220 1.2E-65 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 1.2E-65 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 77 94 1.2E-65 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 Gene3D G3DSA:3.40.50.720 46 251 5.4E-56 T 28-03-2018 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 Gene3D G3DSA:3.40.50.720 1 45 8.2E-8 T 28-03-2018 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 248 1.9E-51 T 28-03-2018 WM46_RS11575 6be8abe837c9209186164121f8d628bf 251 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 250 5.6E-106 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 WM46_RS23200 82940f2434327e27c865b246d8ffb7ea 106 Gene3D G3DSA:1.10.1790.10 2 106 3.7E-9 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS23200 82940f2434327e27c865b246d8ffb7ea 106 SUPERFAMILY SSF63520 25 103 5.49E-7 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS23200 82940f2434327e27c865b246d8ffb7ea 106 TIGRFAM TIGR03582 EF_0829: PRD domain protein, EF_0829/AHA_3910 family 10 105 1.5E-41 T 28-03-2018 IPR020044 PRD domain protein, EF0829/AHA3910 WM46_RS24500 3b69271bd7f397ed6ce3cca6d5d55eab 228 Pfam PF07670 Nucleoside recognition 86 188 4.1E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 WM46_RS14145 06f3e299c279ce351ba5e928c01856ce 220 Pfam PF00484 Carbonic anhydrase 38 187 1.8E-50 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS14145 06f3e299c279ce351ba5e928c01856ce 220 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS14145 06f3e299c279ce351ba5e928c01856ce 220 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS14145 06f3e299c279ce351ba5e928c01856ce 220 Gene3D G3DSA:3.40.1050.10 1 220 4.9E-74 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS14145 06f3e299c279ce351ba5e928c01856ce 220 SUPERFAMILY SSF53056 2 213 2.49E-74 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS14145 06f3e299c279ce351ba5e928c01856ce 220 SMART SM00947 30 192 3.4E-69 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS18755 547c934b10eb0d2bc0f2522cb0d566af 290 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 16 287 23.488 T 28-03-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial WM46_RS18755 547c934b10eb0d2bc0f2522cb0d566af 290 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 18 275 8.9E-104 T 28-03-2018 IPR017039 Virulence factor BrkB WM46_RS18755 547c934b10eb0d2bc0f2522cb0d566af 290 PIRSF PIRSF035875 1 290 1.4E-74 T 28-03-2018 IPR017039 Virulence factor BrkB WM46_RS18755 547c934b10eb0d2bc0f2522cb0d566af 290 Pfam PF03631 Virulence factor BrkB 29 274 9.6E-58 T 28-03-2018 IPR017039 Virulence factor BrkB WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 Gene3D G3DSA:1.10.287.1040 8 75 3.1E-26 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 65 6.4E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 PIRSF PIRSF006488 1 80 3.6E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 SUPERFAMILY SSF116842 2 74 1.7E-22 T 28-03-2018 WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 Pfam PF02609 Exonuclease VII small subunit 11 62 5.5E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 16.785 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS12735 6beb8efbc6d16ec472bd84a6bc62e9c1 80 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 50 6.0E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS25670 21e0d0c49e0ac100744fe08203c97d21 108 Pfam PF05957 Bacterial protein of unknown function (DUF883) 16 107 3.1E-25 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB WM46_RS25670 21e0d0c49e0ac100744fe08203c97d21 108 Gene3D G3DSA:1.20.120.20 6 84 4.3E-4 T 28-03-2018 WM46_RS20075 2edf5f881fd0ef90d29d7410fc6095f7 229 Pfam PF00588 SpoU rRNA Methylase family 20 159 1.9E-36 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM46_RS20075 2edf5f881fd0ef90d29d7410fc6095f7 229 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 197 36.733 T 28-03-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 WM46_RS20075 2edf5f881fd0ef90d29d7410fc6095f7 229 Pfam PF12105 SpoU, rRNA methylase, C-terminal 163 218 2.6E-23 T 28-03-2018 IPR022724 RNA methyltransferase, SpoU/TrmH type, C-terminal GO:0009020 WM46_RS20075 2edf5f881fd0ef90d29d7410fc6095f7 229 Gene3D G3DSA:3.40.1280.10 1 189 2.0E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS20075 2edf5f881fd0ef90d29d7410fc6095f7 229 SUPERFAMILY SSF75217 4 184 1.11E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 Pfam PF12464 Maltose acetyltransferase 7 57 4.5E-16 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 92 109 0.0039 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 129 164 3.1E-11 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 Gene3D G3DSA:2.160.10.10 2 183 1.1E-52 T 28-03-2018 WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 138 166 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 SUPERFAMILY SSF51161 2 182 6.24E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS12455 027cb36e7d240096d3ea28cbfdbf39b4 183 SMART SM01266 5 59 3.3E-18 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 515 973 2.5E-122 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 Gene3D G3DSA:2.160.20.20 127 625 3.1E-58 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 Gene3D G3DSA:2.40.128.130 651 973 7.1E-52 T 28-03-2018 WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 SUPERFAMILY SSF51126 212 622 5.96E-33 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 SUPERFAMILY SSF103515 661 973 1.11E-48 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 SMART SM00869 693 962 4.0E-43 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13210 5f350bd41df0de5e81daca86c706c968 973 Pfam PF03797 Autotransporter beta-domain 696 951 1.2E-49 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS06040 62ea6ecdd4cd9c2d64fd21d78dbc146e 446 Gene3D G3DSA:2.60.40.1090 249 446 9.6E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS06040 62ea6ecdd4cd9c2d64fd21d78dbc146e 446 SUPERFAMILY SSF49401 412 446 2.98E-6 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06040 62ea6ecdd4cd9c2d64fd21d78dbc146e 446 SUPERFAMILY SSF49401 258 301 2.98E-6 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06040 62ea6ecdd4cd9c2d64fd21d78dbc146e 446 SUPERFAMILY SSF49401 345 380 2.98E-6 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06040 62ea6ecdd4cd9c2d64fd21d78dbc146e 446 Pfam PF00419 Fimbrial protein 256 446 8.7E-6 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS08680 23a0097158583851a08a663053888e91 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 2.9E-5 T 28-03-2018 WM46_RS08680 23a0097158583851a08a663053888e91 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 SUPERFAMILY SSF51735 4 243 2.33E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08680 23a0097158583851a08a663053888e91 244 Gene3D G3DSA:3.40.50.720 2 158 1.7E-51 T 28-03-2018 WM46_RS08680 23a0097158583851a08a663053888e91 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 1.6E-101 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS08680 23a0097158583851a08a663053888e91 244 Gene3D G3DSA:3.40.50.720 159 242 4.0E-27 T 28-03-2018 WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 4.0E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.0E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 4.0E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 4.0E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.0E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.0E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08680 23a0097158583851a08a663053888e91 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 6.8E-68 T 28-03-2018 WM46_RS21280 aa67b007fd57cec529080e1292003793 142 ProDom PD097062 ZINC RESISTANCE-ASSOCIATED PERIPLASMIC PRECURSOR SIGNAL YJAI SEQUENCING DIRECT DFFA 1 120 2.0E-33 T 28-03-2018 IPR020365 Zinc resistance-associated protein, ZraP GO:0008270|GO:0042597 WM46_RS21280 aa67b007fd57cec529080e1292003793 142 Pfam PF13801 Heavy-metal resistance 10 123 8.4E-25 T 28-03-2018 IPR025961 Heavy-metal resistance protein WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 ProSitePatterns PS00321 recA signature. 215 223 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 Pfam PF00154 recA bacterial DNA recombination protein 9 270 6.6E-142 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 SUPERFAMILY SSF54752 272 327 5.49E-21 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 Gene3D G3DSA:3.40.50.300 28 270 8.5E-47 T 28-03-2018 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 Gene3D G3DSA:3.30.250.10 272 328 6.1E-26 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 Hamap MF_00268 Protein RecA [recA]. 7 331 50.984 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 PRINTS PR00142 RecA protein signature 129 158 1.9E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 PRINTS PR00142 RecA protein signature 167 196 1.9E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 PRINTS PR00142 RecA protein signature 212 240 1.9E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 PRINTS PR00142 RecA protein signature 299 316 1.9E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 PRINTS PR00142 RecA protein signature 245 274 1.9E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 PRINTS PR00142 RecA protein signature 95 124 1.9E-83 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 6.8E-173 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 SMART SM00382 59 230 4.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25520 e30468fab925131f8860812afc5dbac5 353 SUPERFAMILY SSF52540 6 269 3.85E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 PIRSF PIRSF015626 4 278 4.3E-82 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 34 276 1.3E-97 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 Gene3D G3DSA:3.40.140.10 142 278 1.1E-41 T 28-03-2018 WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 Gene3D G3DSA:3.10.20.10 40 126 5.7E-22 T 28-03-2018 WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 Pfam PF02634 FdhD/NarQ family 38 275 5.0E-70 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 SUPERFAMILY SSF53927 23 276 4.21E-79 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS18675 324301a7987bdb07addb8b23b3370f64 278 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 13 276 33.134 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Pfam PF13090 Polyphosphate kinase C-terminal domain 333 678 3.0E-144 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Gene3D G3DSA:3.30.1840.10 109 307 4.5E-51 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 SUPERFAMILY SSF143724 107 313 6.47E-59 T 28-03-2018 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Gene3D G3DSA:3.30.870.10 502 688 1.6E-32 T 28-03-2018 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Pfam PF13089 Polyphosphate kinase N-terminal domain 7 109 3.6E-31 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 PIRSF PIRSF015589 1 688 1.4E-240 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 SUPERFAMILY SSF140356 3 105 7.85E-34 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Gene3D G3DSA:3.30.870.10 316 501 1.8E-26 T 28-03-2018 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Hamap MF_00347 Polyphosphate kinase [ppk]. 5 683 27.327 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 679 1.6E-257 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Gene3D G3DSA:1.20.58.310 9 108 3.4E-34 T 28-03-2018 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 SUPERFAMILY SSF56024 503 685 4.26E-69 T 28-03-2018 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 Pfam PF02503 Polyphosphate kinase middle domain 119 319 1.1E-41 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 WM46_RS00765 6de8063dcb28584b96fad59b2d80a25e 688 SUPERFAMILY SSF56024 320 499 1.26E-56 T 28-03-2018 WM46_RS05490 0c20694d3f756c1dcb9c344ce3324e7c 379 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 249 335 1.4E-27 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 WM46_RS05490 0c20694d3f756c1dcb9c344ce3324e7c 379 Gene3D G3DSA:1.20.810.10 3 379 3.6E-111 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 WM46_RS05490 0c20694d3f756c1dcb9c344ce3324e7c 379 Pfam PF00033 Cytochrome b/b6/petB 17 189 2.5E-53 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 WM46_RS05490 0c20694d3f756c1dcb9c344ce3324e7c 379 SUPERFAMILY SSF81648 212 340 4.32E-35 T 28-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 WM46_RS05490 0c20694d3f756c1dcb9c344ce3324e7c 379 SUPERFAMILY SSF81342 6 251 2.35E-68 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 PIRSF PIRSF000141 1 418 3.5E-168 T 28-03-2018 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 Gene3D G3DSA:3.50.50.60 3 419 6.0E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 Pfam PF00890 FAD binding domain 4 399 1.2E-62 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 Hamap MF_00753 Anaerobic glycerol-3-phosphate dehydrogenase subunit B [glpB]. 1 415 48.509 T 28-03-2018 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 SUPERFAMILY SSF51905 249 414 1.4E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 SUPERFAMILY SSF51905 1 169 1.4E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01965 ab7a289945704593679ac03ba970117d 419 TIGRFAM TIGR03378 glycerol3P_GlpB: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit 3 411 4.1E-173 T 28-03-2018 IPR009158 Glycerol-3-phosphate dehydrogenase, GlpB subunit GO:0004368|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 WM46_RS01410 42856436d21bfc86bfa23345a480f1c1 110 SUPERFAMILY SSF160113 1 57 6.67E-20 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 WM46_RS01410 42856436d21bfc86bfa23345a480f1c1 110 Gene3D G3DSA:3.30.160.160 54 99 4.0E-12 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 WM46_RS01410 42856436d21bfc86bfa23345a480f1c1 110 Gene3D G3DSA:3.30.160.160 4 48 7.0E-18 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 WM46_RS01410 42856436d21bfc86bfa23345a480f1c1 110 SUPERFAMILY SSF160113 61 108 4.19E-15 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 WM46_RS01410 42856436d21bfc86bfa23345a480f1c1 110 Pfam PF07411 Domain of unknown function (DUF1508) 11 57 9.6E-22 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 WM46_RS01410 42856436d21bfc86bfa23345a480f1c1 110 Pfam PF07411 Domain of unknown function (DUF1508) 61 108 8.9E-20 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 Gene3D G3DSA:3.40.50.1100 101 197 3.8E-18 T 28-03-2018 WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 Gene3D G3DSA:3.40.50.1100 322 395 1.7E-13 T 28-03-2018 WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 Gene3D G3DSA:3.40.50.1100 198 319 1.6E-39 T 28-03-2018 WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 SUPERFAMILY SSF53686 1 425 3.93E-131 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 Pfam PF14821 Threonine synthase N terminus 8 80 4.1E-13 T 28-03-2018 IPR029144 Threonine synthase, N-terminal WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 97 111 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 TIGRFAM TIGR00260 thrC: threonine synthase 52 397 3.3E-127 T 28-03-2018 IPR004450 Threonine synthase-like WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 97 369 9.7E-24 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS14800 6431d20d61cac532113d03b2d5b3e335 427 Gene3D G3DSA:3.90.1380.10 1 81 1.4E-18 T 28-03-2018 IPR029144 Threonine synthase, N-terminal WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 Gene3D G3DSA:3.20.20.70 10 251 1.2E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 SUPERFAMILY SSF51395 12 321 7.33E-70 T 28-03-2018 WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 PIRSF PIRSF006621 1 327 5.2E-72 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 4 329 53.003 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 Pfam PF01207 Dihydrouridine synthase (Dus) 16 325 3.8E-97 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 13 328 7.7E-171 T 28-03-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 WM46_RS21620 ad4710b82778c259366a9b1000681ed1 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS02575 500c5efdf22322f437d63c8a88f9b5fc 305 Gene3D G3DSA:3.40.190.10 18 173 1.8E-25 T 28-03-2018 WM46_RS02575 500c5efdf22322f437d63c8a88f9b5fc 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 26 300 1.5E-60 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 WM46_RS02575 500c5efdf22322f437d63c8a88f9b5fc 305 Gene3D G3DSA:3.40.190.10 174 303 4.8E-18 T 28-03-2018 WM46_RS02575 500c5efdf22322f437d63c8a88f9b5fc 305 SUPERFAMILY SSF53850 26 303 5.97E-59 T 28-03-2018 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Gene3D G3DSA:1.10.287.130 280 341 1.7E-17 T 28-03-2018 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Pfam PF01627 Hpt domain 686 758 1.6E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SUPERFAMILY SSF47226 661 773 9.29E-28 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 PIRSF PIRSF003182 1 778 0.0 T 28-03-2018 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 445 8.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 8.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 459 8.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 485 8.8E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SMART SM00091 155 221 2.1E-7 T 28-03-2018 IPR000014 PAS domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Pfam PF00989 PAS fold 156 266 5.1E-18 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SMART SM00388 282 347 1.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Gene3D G3DSA:1.20.120.160 646 763 3.5E-17 T 28-03-2018 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SMART SM00387 394 507 2.2E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 276 5.0E-14 T 28-03-2018 IPR000014 PAS domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SUPERFAMILY SSF55785 140 267 9.77E-21 T 28-03-2018 IPR000014 PAS domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Gene3D G3DSA:3.40.50.2300 515 645 7.2E-30 T 28-03-2018 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Pfam PF00072 Response regulator receiver domain 528 639 2.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Gene3D G3DSA:3.30.450.20 102 279 1.5E-25 T 28-03-2018 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SUPERFAMILY SSF55874 336 503 6.68E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 346 2.2E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SUPERFAMILY SSF47384 269 347 5.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Gene3D G3DSA:1.10.287.970 3 88 7.3E-39 T 28-03-2018 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Gene3D G3DSA:3.30.565.10 342 506 5.1E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SUPERFAMILY SSF52172 526 645 3.27E-27 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SMART SM00073 675 772 1.6E-20 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 SMART SM00448 526 639 5.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS16975 10045cf5f0adc0191d3df1fcfa5e8b57 778 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 504 2.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12825 8570a685b3092c8b3676f26b53a5a941 356 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 5.0E-169 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM46_RS12825 8570a685b3092c8b3676f26b53a5a941 356 Pfam PF02547 Queuosine biosynthesis protein 4 343 6.5E-133 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM46_RS12825 8570a685b3092c8b3676f26b53a5a941 356 SUPERFAMILY SSF111337 1 343 9.68E-139 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM46_RS12825 8570a685b3092c8b3676f26b53a5a941 356 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 47.809 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 WM46_RS12825 8570a685b3092c8b3676f26b53a5a941 356 Gene3D G3DSA:3.40.1780.10 175 344 6.7E-67 T 28-03-2018 WM46_RS12825 8570a685b3092c8b3676f26b53a5a941 356 Gene3D G3DSA:3.40.1780.10 1 139 8.3E-31 T 28-03-2018 WM46_RS14395 646ae1a04e2d10f5288059da5a361dee 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14395 646ae1a04e2d10f5288059da5a361dee 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 9.3E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14395 646ae1a04e2d10f5288059da5a361dee 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14395 646ae1a04e2d10f5288059da5a361dee 360 Pfam PF00953 Glycosyl transferase family 4 99 284 6.9E-34 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 WM46_RS14395 646ae1a04e2d10f5288059da5a361dee 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 1.8E-162 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14395 646ae1a04e2d10f5288059da5a361dee 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.885 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS21220 34b0430a0b4d3555c1b0b1cf115f453e 256 Gene3D G3DSA:3.20.20.70 1 256 1.9E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS21220 34b0430a0b4d3555c1b0b1cf115f453e 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 247 5.4E-109 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 WM46_RS21220 34b0430a0b4d3555c1b0b1cf115f453e 256 Hamap MF_00443 Thiazole synthase [thiG]. 1 253 42.943 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 WM46_RS21220 34b0430a0b4d3555c1b0b1cf115f453e 256 SUPERFAMILY SSF110399 1 236 8.5E-82 T 28-03-2018 WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 Pfam PF00664 ABC transporter transmembrane region 27 295 1.4E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 Pfam PF00005 ABC transporter 357 505 1.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 Gene3D G3DSA:1.20.1560.10 6 326 1.1E-62 T 28-03-2018 WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 SMART SM00382 366 557 1.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 Gene3D G3DSA:3.40.50.300 327 581 5.2E-65 T 28-03-2018 WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 SUPERFAMILY SSF52540 335 576 9.52E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 SUPERFAMILY SSF90123 12 325 1.29E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS12565 7bf49baf8535a63f8be684287ad30aad 592 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS14225 8dd1af29a9e6e54627718cb5c08d00f0 120 Pfam PF06062 Uncharacterised protein family (UPF0231) 1 117 1.9E-42 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 WM46_RS14225 8dd1af29a9e6e54627718cb5c08d00f0 120 Hamap MF_01053 UPF0231 protein YacL [yacL]. 1 119 29.523 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 WM46_RS14225 8dd1af29a9e6e54627718cb5c08d00f0 120 PIRSF PIRSF006287 1 120 1.4E-49 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 WM46_RS14225 8dd1af29a9e6e54627718cb5c08d00f0 120 ProDom PD020773 UPF0231 YACL UNCHARACTERISED UCP006287 VC0605 UNCHARACTERIZED 3'REGION VV2750 BCR OXIDASE 1 117 9.0E-59 T 28-03-2018 IPR008249 Uncharacterised protein family UPF0231 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Gene3D G3DSA:3.40.50.970 167 518 1.6E-93 T 28-03-2018 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 SUPERFAMILY SSF52518 575 791 2.02E-52 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Gene3D G3DSA:3.40.50.970 591 800 4.8E-58 T 28-03-2018 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 788 930 5.8E-54 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 SUPERFAMILY SSF52518 121 546 1.69E-88 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 14 930 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Gene3D G3DSA:1.10.287.1150 83 166 2.4E-24 T 28-03-2018 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Pfam PF02779 Transketolase, pyrimidine binding domain 591 785 3.6E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 50 1.9E-15 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 SMART SM00861 591 784 3.0E-65 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 Pfam PF00676 Dehydrogenase E1 component 218 511 3.5E-48 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 WM46_RS10985 712e660019ffdbaba27f8e3b70da382a 933 PIRSF PIRSF000157 1 932 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 Gene3D G3DSA:1.25.20.10 28 390 2.3E-51 T 28-03-2018 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 Gene3D G3DSA:1.10.1240.20 404 472 2.4E-18 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 Gene3D G3DSA:1.10.530.10 473 645 2.7E-42 T 28-03-2018 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 SUPERFAMILY SSF53955 479 641 1.34E-52 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 501 529 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 Pfam PF14718 Soluble lytic murein transglycosylase L domain 408 472 3.5E-22 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 SUPERFAMILY SSF48435 28 477 2.09E-135 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 WM46_RS14875 c9c96f8d239ec50ef0f280d038fcf068 645 Pfam PF01464 Transglycosylase SLT domain 484 595 5.7E-34 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS14445 54c9f129da71d17937be459084601275 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14445 54c9f129da71d17937be459084601275 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 73 9.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14445 54c9f129da71d17937be459084601275 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 62 9.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14445 54c9f129da71d17937be459084601275 316 Gene3D G3DSA:1.10.10.10 6 102 6.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14445 54c9f129da71d17937be459084601275 316 SUPERFAMILY SSF46785 21 100 1.09E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14445 54c9f129da71d17937be459084601275 316 SUPERFAMILY SSF53850 107 313 2.9E-36 T 28-03-2018 WM46_RS14445 54c9f129da71d17937be459084601275 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 26 83 1.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14445 54c9f129da71d17937be459084601275 316 Gene3D G3DSA:3.40.190.10 199 286 1.6E-6 T 28-03-2018 WM46_RS14445 54c9f129da71d17937be459084601275 316 Pfam PF03466 LysR substrate binding domain 140 313 1.3E-14 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS14445 54c9f129da71d17937be459084601275 316 Gene3D G3DSA:3.40.190.10 110 198 6.6E-8 T 28-03-2018 WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 SUPERFAMILY SSF51126 73 508 2.42E-32 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 Pfam PF03212 Pertactin 381 501 1.4E-10 T 28-03-2018 IPR004899 Pertactin, central region WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 SUPERFAMILY SSF103515 541 855 4.18E-53 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 140 185 1.7E-8 T 28-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 323 351 4.1E-8 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 Gene3D G3DSA:2.40.128.130 533 855 2.2E-56 T 28-03-2018 WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 404 855 3.1E-124 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 Gene3D G3DSA:2.160.20.20 13 506 3.7E-39 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 SMART SM00869 575 844 1.2E-46 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13190 e5a701247eb2bb0a3fc13ec56a6ab13c 855 Pfam PF03797 Autotransporter beta-domain 578 833 1.3E-52 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13070 59964a2bfca82d2a7d711d2224b2f539 275 SUPERFAMILY SSF161098 75 258 2.22E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13070 59964a2bfca82d2a7d711d2224b2f539 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 269 1.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13070 59964a2bfca82d2a7d711d2224b2f539 275 Gene3D G3DSA:1.10.3720.10 18 273 2.2E-32 T 28-03-2018 WM46_RS11315 5d46a094cbb7e4f7b91d44c17a218196 512 SUPERFAMILY SSF56317 215 490 8.11E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS11315 5d46a094cbb7e4f7b91d44c17a218196 512 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 63 458 2.8E-116 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 WM46_RS11315 5d46a094cbb7e4f7b91d44c17a218196 512 Pfam PF00795 Carbon-nitrogen hydrolase 223 478 5.4E-39 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS11315 5d46a094cbb7e4f7b91d44c17a218196 512 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 10 495 24.072 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 WM46_RS11315 5d46a094cbb7e4f7b91d44c17a218196 512 Gene3D G3DSA:3.60.110.10 219 481 6.8E-36 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 Hamap MF_01987 Ribokinase [rbsK]. 2 301 21.19 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 Gene3D G3DSA:3.40.1190.20 1 310 2.3E-70 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 SUPERFAMILY SSF53613 2 302 2.18E-73 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 PRINTS PR00990 Ribokinase signature 105 118 1.8E-23 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 PRINTS PR00990 Ribokinase signature 173 188 1.8E-23 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 PRINTS PR00990 Ribokinase signature 6 27 1.8E-23 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 PRINTS PR00990 Ribokinase signature 33 52 1.8E-23 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 PRINTS PR00990 Ribokinase signature 217 228 1.8E-23 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 Pfam PF00294 pfkB family carbohydrate kinase 4 285 5.5E-54 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS09370 bcf84a7eaa2ce67f00ebfdb70e483dd7 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 Gene3D G3DSA:3.30.980.20 94 183 5.9E-29 T 28-03-2018 WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 TIGRFAM TIGR02463 MPGP_rel: mannosyl-3-phosphoglycerate phosphatase homolog 9 232 9.1E-90 T 28-03-2018 WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 Pfam PF08282 haloacid dehalogenase-like hydrolase 10 232 1.2E-13 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 Gene3D G3DSA:3.40.50.1000 2 72 0.0027 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 9 267 6.7E-89 T 28-03-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 SUPERFAMILY SSF56784 7 232 2.57E-44 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03755 f0a56c02c36dfc6030d29a9443435561 271 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 9 231 1.9E-37 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Pfam PF00809 Pterin binding enzyme 360 598 9.5E-62 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Pfam PF02574 Homocysteine S-methyltransferase 17 325 5.7E-80 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 PIRSF PIRSF000381 1 1195 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 SUPERFAMILY SSF51717 356 630 3.92E-88 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Gene3D G3DSA:1.10.1240.10 652 731 1.2E-37 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 SMART SM01018 657 740 7.7E-45 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 SUPERFAMILY SSF82282 7 399 3.4E-119 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Gene3D G3DSA:3.40.50.280 732 903 2.9E-55 T 28-03-2018 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 SUPERFAMILY SSF56507 903 1226 4.71E-135 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Gene3D G3DSA:3.10.196.10 956 1080 7.4E-46 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Gene3D G3DSA:3.10.196.10 1081 1227 2.3E-64 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Pfam PF02310 B12 binding domain 748 840 4.2E-18 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 SUPERFAMILY SSF47644 653 739 1.02E-28 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 938 1208 1.1E-126 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Pfam PF02607 B12 binding domain 660 733 3.5E-25 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 TIGRFAM TIGR02082 metH: methionine synthase 12 1192 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Gene3D G3DSA:3.20.20.20 345 644 7.2E-75 T 28-03-2018 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 SUPERFAMILY SSF52242 742 894 3.66E-48 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM46_RS21360 4169e188c63e97a303225f1d9e59df44 1227 Gene3D G3DSA:3.20.20.330 2 336 1.3E-112 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Pfam PF00117 Glutamine amidotransferase class-I 6 186 1.6E-43 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00097 Anthranilate synthase component II signature 4 18 2.0E-33 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00097 Anthranilate synthase component II signature 79 90 2.0E-33 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00097 Anthranilate synthase component II signature 166 179 2.0E-33 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00097 Anthranilate synthase component II signature 52 61 2.0E-33 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00097 Anthranilate synthase component II signature 124 136 2.0E-33 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00097 Anthranilate synthase component II signature 104 112 2.0E-33 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Gene3D G3DSA:3.40.1030.10 276 530 4.8E-91 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 186 7.5E-55 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 SUPERFAMILY SSF52317 3 191 9.54E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Pfam PF02885 Glycosyl transferase family, helical bundle domain 202 262 2.0E-14 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 202 530 38.642 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Gene3D G3DSA:1.20.970.10 193 275 5.7E-16 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 204 528 6.9E-129 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 6.6E-13 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 6.6E-13 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 6.6E-13 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 7.3E-5 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 7.3E-5 T 28-03-2018 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 SUPERFAMILY SSF47648 200 266 4.45E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 SUPERFAMILY SSF52418 269 527 1.06E-90 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Gene3D G3DSA:3.40.50.880 1 192 8.7E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS05845 2900ebdb265781548d3b5739306f322e 531 Pfam PF00591 Glycosyl transferase family, a/b domain 273 521 5.4E-101 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS16205 9ad9ff1a9fee41eac64f9bc7706891b9 433 SMART SM01118 2 202 5.9E-41 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 WM46_RS16205 9ad9ff1a9fee41eac64f9bc7706891b9 433 Pfam PF01928 CYTH domain 3 196 1.6E-34 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 WM46_RS16205 9ad9ff1a9fee41eac64f9bc7706891b9 433 SUPERFAMILY SSF55154 1 218 9.16E-52 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 WM46_RS16205 9ad9ff1a9fee41eac64f9bc7706891b9 433 Gene3D G3DSA:2.40.320.10 1 211 4.5E-45 T 28-03-2018 WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 SUPERFAMILY SSF53822 258 287 7.85E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 SUPERFAMILY SSF53822 529 682 7.85E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 SUPERFAMILY SSF53822 360 490 7.85E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Pfam PF04348 LppC putative lipoprotein 40 285 5.8E-46 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Pfam PF04348 LppC putative lipoprotein 355 678 1.0E-86 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Gene3D G3DSA:3.40.50.2300 168 239 0.04 T 28-03-2018 WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Gene3D G3DSA:3.40.50.2300 530 671 9.4E-15 T 28-03-2018 WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Gene3D G3DSA:3.40.50.2300 255 486 2.7E-46 T 28-03-2018 WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Hamap MF_01890 Penicillin-binding protein activator LpoA [lpoA]. 1 678 36.246 T 28-03-2018 IPR007443 Penicillin-binding protein activator LpoA WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 SUPERFAMILY SSF48435 50 151 6.67E-5 T 28-03-2018 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 WM46_RS16660 76a3c25e15606c87c7a481f5312a70ff 684 Gene3D G3DSA:1.25.40.10 49 167 1.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS16215 cdc27d0a6c9c75280fc0e15d1732f97b 206 Pfam PF08239 Bacterial SH3 domain 35 83 4.3E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type WM46_RS16215 cdc27d0a6c9c75280fc0e15d1732f97b 206 Gene3D G3DSA:1.20.5.50 91 170 2.1E-6 T 28-03-2018 WM46_RS16215 cdc27d0a6c9c75280fc0e15d1732f97b 206 Gene3D G3DSA:2.30.30.410 14 90 2.9E-10 T 28-03-2018 WM46_RS16215 cdc27d0a6c9c75280fc0e15d1732f97b 206 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 27 204 2.9E-52 T 28-03-2018 IPR016476 SH3 domain protein WM46_RS16215 cdc27d0a6c9c75280fc0e15d1732f97b 206 PIRSF PIRSF006158 1 205 2.9E-71 T 28-03-2018 IPR016476 SH3 domain protein WM46_RS16215 cdc27d0a6c9c75280fc0e15d1732f97b 206 SMART SM00287 23 88 9.7E-13 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type WM46_RS11370 6937e34756d9866dd68289d393bed9a3 361 Gene3D G3DSA:3.90.1150.10 263 355 6.8E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS11370 6937e34756d9866dd68289d393bed9a3 361 Pfam PF00155 Aminotransferase class I and II 25 350 2.6E-39 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS11370 6937e34756d9866dd68289d393bed9a3 361 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 8 350 5.4E-100 T 28-03-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 WM46_RS11370 6937e34756d9866dd68289d393bed9a3 361 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 213 226 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 WM46_RS11370 6937e34756d9866dd68289d393bed9a3 361 Gene3D G3DSA:3.40.640.10 38 262 3.6E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS11370 6937e34756d9866dd68289d393bed9a3 361 SUPERFAMILY SSF53383 6 354 8.76E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 3.2E-17 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 SUPERFAMILY SSF50465 298 393 3.17E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 200 5.6E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 393 2.9E-239 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Gene3D G3DSA:3.40.50.300 2 74 5.6E-11 T 28-03-2018 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 7.9E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Gene3D G3DSA:3.40.50.300 75 203 9.6E-31 T 28-03-2018 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Gene3D G3DSA:2.40.30.10 300 393 4.4E-33 T 28-03-2018 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 1.5E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Gene3D G3DSA:2.40.30.10 206 299 9.6E-33 T 28-03-2018 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 SUPERFAMILY SSF52540 6 219 2.06E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 60.984 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS17575 91e6850f5ed910ca280a51ec5e84c3d2 394 SUPERFAMILY SSF50447 205 301 2.16E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 332 8.3E-138 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 SUPERFAMILY SSF53671 2 332 1.26E-99 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 Gene3D G3DSA:3.40.50.1370 164 334 2.5E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 333 83.174 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 330 2.1E-54 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 5.7E-49 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 1.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 1.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 1.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 1.2E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 Gene3D G3DSA:3.40.50.1370 5 163 2.5E-57 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 5.9E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 5.9E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 5.9E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 5.9E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23375 ede0ae9ba29bebb264475bb44e9b5284 334 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 5.9E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS16575 b75d712706c1bd44dbaac901e917f4c7 306 Pfam PF00480 ROK family 3 298 1.7E-60 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS16575 b75d712706c1bd44dbaac901e917f4c7 306 Gene3D G3DSA:3.30.420.40 1 114 3.4E-19 T 28-03-2018 WM46_RS16575 b75d712706c1bd44dbaac901e917f4c7 306 Gene3D G3DSA:3.30.420.40 115 303 1.3E-44 T 28-03-2018 WM46_RS16575 b75d712706c1bd44dbaac901e917f4c7 306 SUPERFAMILY SSF53067 1 299 2.64E-53 T 28-03-2018 WM46_RS05195 009c1d9e7c389ba2537bc3fc189953f7 203 Gene3D G3DSA:1.10.530.10 21 203 1.5E-28 T 28-03-2018 WM46_RS05195 009c1d9e7c389ba2537bc3fc189953f7 203 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 60 88 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM46_RS05195 009c1d9e7c389ba2537bc3fc189953f7 203 SUPERFAMILY SSF53955 37 197 5.93E-26 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS05195 009c1d9e7c389ba2537bc3fc189953f7 203 Pfam PF01464 Transglycosylase SLT domain 43 168 2.3E-28 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS05195 009c1d9e7c389ba2537bc3fc189953f7 203 Hamap MF_01381 Endo-type membrane-bound lytic murein transglycosylase A [emtA]. 1 203 64.192 T 28-03-2018 IPR023946 Endo-type membrane-bound lytic murein transglycosylase A GO:0008932|GO:0009279|GO:0016837|GO:0016998 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 SUPERFAMILY SSF56601 11 285 1.88E-83 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 265 7.9E-101 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 Gene3D G3DSA:3.40.710.10 22 302 1.6E-51 T 28-03-2018 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 Gene3D G3DSA:2.60.410.10 303 376 6.7E-19 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.4E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.4E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.4E-18 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 SUPERFAMILY SSF69189 285 378 8.63E-25 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 285 376 8.7E-24 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS10240 4a93112ed2f99c9c4126d4e6fb693382 400 SMART SM00936 285 376 4.6E-35 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 487 503 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 525 537 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 113 127 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 70 83 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 268 281 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 505 522 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 35 50 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 736 752 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR00418 DNA topoisomerase II family signature 420 434 9.3E-71 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Pfam PF00204 DNA gyrase B 221 390 3.7E-59 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 SUPERFAMILY SSF54211 221 392 7.4E-62 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 SMART SM00387 31 175 4.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 173 4.4E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Gene3D G3DSA:3.30.230.10 221 392 2.8E-66 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Pfam PF01751 Toprim domain 419 531 4.1E-18 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 470 479 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 220 242 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 312 328 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 181 196 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 196 209 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 757 769 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 773 789 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 5 15 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 360 374 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 PRINTS PR01159 DNA gyrase subunit B signature 374 394 2.1E-80 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 SMART SM00433 35 797 3.1E-282 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 5 804 0.0 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 733 793 6.6E-30 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 SUPERFAMILY SSF55874 4 220 6.55E-77 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 ProSitePatterns PS00177 DNA topoisomerase II signature. 422 430 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Gene3D G3DSA:3.40.50.670 402 801 2.7E-108 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Gene3D G3DSA:3.30.565.10 17 220 6.6E-76 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 SUPERFAMILY SSF56719 730 795 1.46E-86 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 SUPERFAMILY SSF56719 394 560 1.46E-86 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM46_RS19665 120f1672d2d20adc90cd6aecf89a7f0f 804 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 2 804 115.769 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 SUPERFAMILY SSF52540 1 343 3.49E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 357 96.719 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 Gene3D G3DSA:3.40.50.300 1 357 4.5E-31 T 28-03-2018 WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 355 3.2E-137 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 ProSitePatterns PS00618 RecF protein signature 2. 298 316 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 354 9.2E-40 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal WM46_RS19660 b18aad6fa21fc33c6d0dee0616b107e7 357 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 WM46_RS13080 98722e0670c5bfd95ee3fdf9edbff0bf 320 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 25 320 9.6E-157 T 28-03-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 WM46_RS13080 98722e0670c5bfd95ee3fdf9edbff0bf 320 SUPERFAMILY SSF53850 34 306 2.26E-47 T 28-03-2018 WM46_RS13080 98722e0670c5bfd95ee3fdf9edbff0bf 320 Gene3D G3DSA:3.40.190.10 20 119 4.7E-11 T 28-03-2018 WM46_RS13080 98722e0670c5bfd95ee3fdf9edbff0bf 320 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 24 247 3.3E-26 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 WM46_RS13080 98722e0670c5bfd95ee3fdf9edbff0bf 320 SMART SM00062 24 239 1.5E-27 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS13080 98722e0670c5bfd95ee3fdf9edbff0bf 320 Gene3D G3DSA:3.40.190.10 120 320 8.9E-41 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82714 183 272 3.01E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Pfam PF00873 AcrB/AcrD/AcrF family 1 1020 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Gene3D G3DSA:3.30.2090.10 714 802 5.6E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1022 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82693 562 664 5.06E-26 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Gene3D G3DSA:1.20.1640.10 804 1022 7.4E-41 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Gene3D G3DSA:3.30.2090.10 181 276 7.5E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82714 715 801 1.12E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82866 824 1020 4.97E-44 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 549 566 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 618 632 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 9.8E-82 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82693 136 182 1.38E-23 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82693 275 331 1.38E-23 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82693 38 130 1.59E-26 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Gene3D G3DSA:3.30.70.1430 38 140 5.9E-27 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82693 665 714 2.27E-24 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82693 801 850 2.27E-24 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 SUPERFAMILY SSF82866 298 498 1.83E-46 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Gene3D G3DSA:1.20.1640.10 288 509 1.1E-45 T 28-03-2018 WM46_RS16510 1db2737123bb05af8ced09a4958c5ad2 1031 Gene3D G3DSA:3.30.70.1430 564 664 1.1E-19 T 28-03-2018 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 PRINTS PR00069 Aldo-keto reductase signature 81 99 2.8E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 PRINTS PR00069 Aldo-keto reductase signature 149 178 2.8E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 PRINTS PR00069 Aldo-keto reductase signature 114 131 2.8E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 PRINTS PR00069 Aldo-keto reductase signature 186 210 2.8E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 PRINTS PR00069 Aldo-keto reductase signature 25 49 2.8E-45 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 Gene3D G3DSA:3.20.20.100 1 263 2.9E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 SUPERFAMILY SSF51430 2 257 1.13E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 114 131 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 Pfam PF00248 Aldo/keto reductase family 8 250 1.7E-49 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS13785 591fe10c1a331013138837547f4e48c6 267 PIRSF PIRSF000097 1 265 1.9E-67 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 SUPERFAMILY SSF52283 1 133 5.27E-26 T 28-03-2018 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 Hamap MF_01667 Glyoxylate/hydroxypyruvate reductase B [ghrB]. 1 324 73.295 T 28-03-2018 IPR023756 Glyoxylate/hydroxypyruvate reductase B GO:0016618|GO:0030267|GO:0055114 KEGG: 00260+1.1.1.81|KEGG: 00620+1.1.1.79|KEGG: 00630+1.1.1.79+1.1.1.81|MetaCyc: PWY-1622 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 Gene3D G3DSA:3.40.50.720 1 113 2.5E-26 T 28-03-2018 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 2.4E-29 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 287 7.0E-61 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 Gene3D G3DSA:3.40.50.720 114 290 4.7E-54 T 28-03-2018 WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 SUPERFAMILY SSF51735 100 288 7.74E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20520 02b1a89c211c73377c5fb0a8b523f6f2 324 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 Gene3D G3DSA:1.20.1560.10 1 323 5.2E-58 T 28-03-2018 WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 SUPERFAMILY SSF90123 7 327 1.07E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 SUPERFAMILY SSF52540 328 572 6.91E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 SMART SM00382 361 547 5.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 Pfam PF00005 ABC transporter 352 500 1.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 Pfam PF00664 ABC transporter transmembrane region 22 291 6.3E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 Gene3D G3DSA:3.40.50.300 324 577 1.2E-65 T 28-03-2018 WM46_RS12570 089155a32c4f3108c35d586c5ff68bea 590 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 SUPERFAMILY SSF54826 27 157 7.96E-26 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 Pfam PF13378 Enolase C-terminal domain-like 187 383 4.0E-60 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 SMART SM00922 176 273 4.3E-27 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 223 254 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 Gene3D G3DSA:3.20.20.120 163 381 2.6E-61 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 60 156 5.3E-13 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 SUPERFAMILY SSF51604 144 385 3.01E-71 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS06675 70f5b6e29d399df56c2887711961e7a7 398 Gene3D G3DSA:3.30.390.10 21 162 2.0E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 Gene3D G3DSA:1.10.220.30 5 67 3.4E-10 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 Pfam PF14841 FliG middle domain 116 187 7.9E-24 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PIRSF PIRSF003161 1 332 1.3E-117 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 Gene3D G3DSA:1.10.220.30 68 190 2.4E-21 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 Gene3D G3DSA:1.10.220.30 195 332 1.5E-29 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 Pfam PF14842 FliG N-terminal domain 5 104 3.9E-29 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 SUPERFAMILY SSF48029 7 105 2.88E-18 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 SUPERFAMILY SSF48029 116 325 9.68E-63 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 226 246 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 272 298 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 195 220 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 5 21 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 115 138 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 34 60 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 PRINTS PR00954 Flagellar motor switch protein FliG signature 248 268 1.8E-75 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 3 332 2.1E-150 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 WM46_RS03830 00dc9821aa3387f3178c032b0aabe7de 332 Pfam PF01706 FliG C-terminal domain 219 324 2.2E-37 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 253 439 6.0E-27 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 TIGRFAM TIGR02627 rhamnulo_kin: rhamnulokinase 7 460 7.2E-235 T 28-03-2018 IPR013449 Rhamnulokinase GO:0008993|GO:0019301 KEGG: 00040+2.7.1.5|KEGG: 00051+2.7.1.5 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 SUPERFAMILY SSF53067 6 245 4.01E-48 T 28-03-2018 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 243 1.4E-31 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 SUPERFAMILY SSF53067 250 472 4.75E-32 T 28-03-2018 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 Gene3D G3DSA:3.30.420.40 236 485 2.0E-41 T 28-03-2018 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 Hamap MF_01535 Rhamnulokinase [rhaB]. 6 483 53.238 T 28-03-2018 IPR013449 Rhamnulokinase GO:0008993|GO:0019301 KEGG: 00040+2.7.1.5|KEGG: 00051+2.7.1.5 WM46_RS18565 78a596875fdd40496e2c562150e8a480 489 Gene3D G3DSA:3.30.420.40 1 235 2.7E-46 T 28-03-2018 WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 Gene3D G3DSA:3.40.190.10 182 268 2.3E-18 T 28-03-2018 WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.3E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 Gene3D G3DSA:3.40.190.10 83 181 1.6E-15 T 28-03-2018 WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 SUPERFAMILY SSF53850 91 301 5.97E-39 T 28-03-2018 WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 Pfam PF03466 LysR substrate binding domain 91 296 1.1E-38 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 SUPERFAMILY SSF46785 5 87 2.33E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09980 e75247585913dacef9b9654ade8e8bd2 303 Gene3D G3DSA:1.10.10.10 3 82 9.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Gene3D G3DSA:3.40.50.740 120 329 2.1E-36 T 28-03-2018 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 726 753 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 61 80 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 SUPERFAMILY SSF53706 57 692 1.83E-170 T 28-03-2018 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Gene3D G3DSA:2.20.25.90 50 119 1.1E-17 T 28-03-2018 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 14 811 0.0 T 28-03-2018 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Gene3D G3DSA:2.40.40.20 672 811 7.7E-33 T 28-03-2018 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 56 115 8.4E-14 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Pfam PF00384 Molybdopterin oxidoreductase 118 568 9.8E-85 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 SMART SM00926 56 115 2.3E-10 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Pfam PF01568 Molydopterin dinucleotide binding domain 690 803 1.3E-26 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Gene3D G3DSA:3.40.50.740 338 611 9.3E-44 T 28-03-2018 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 Gene3D G3DSA:3.40.228.10 612 671 1.1E-11 T 28-03-2018 WM46_RS07215 5fefb56ca9a3d04489e109c064e23e96 811 SUPERFAMILY SSF50692 636 811 1.33E-37 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Pfam PF08521 Two-component sensor kinase N-terminal 22 158 7.4E-6 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 SUPERFAMILY SSF55874 291 448 2.23E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 301 5.6E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 SMART SM00388 236 302 1.2E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 SMART SM00387 348 449 3.8E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Gene3D G3DSA:3.30.565.10 306 449 2.3E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 447 7.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Gene3D G3DSA:1.20.5.1040 7 58 1.1E-10 T 28-03-2018 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Gene3D G3DSA:1.20.5.1040 130 183 1.8E-14 T 28-03-2018 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 Gene3D G3DSA:1.10.287.130 225 298 4.6E-12 T 28-03-2018 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 8.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 8.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS16065 7e38079ccc6ea9e0646df787fdafcd95 449 SUPERFAMILY SSF47384 219 301 1.73E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 Gene3D G3DSA:1.10.260.40 33 73 7.1E-5 T 28-03-2018 WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 SUPERFAMILY SSF53098 118 290 1.52E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 Gene3D G3DSA:3.30.420.10 114 323 5.1E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 SUPERFAMILY SSF46689 2 39 9.41E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 Gene3D G3DSA:1.10.10.60 1 32 3.5E-14 T 28-03-2018 WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 Pfam PF13936 Helix-turn-helix domain 2 39 3.4E-7 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain WM46_RS26080 a352a3e0c959e2d28a8574ecdc98e0dc 341 Pfam PF00665 Integrase core domain 118 243 1.7E-23 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 949 16.198 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Pfam PF08264 Anticodon-binding domain of tRNA 674 823 1.3E-41 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 886 944 5.4E-16 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 932 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 SUPERFAMILY SSF50677 191 365 4.06E-57 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Gene3D G3DSA:3.40.50.620 2 630 1.7E-135 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 SUPERFAMILY SSF46589 884 947 9.42E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 2.0E-35 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 2.0E-35 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 PRINTS PR00986 Valyl-tRNA synthetase signature 500 518 2.0E-35 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 PRINTS PR00986 Valyl-tRNA synthetase signature 469 490 2.0E-35 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 PRINTS PR00986 Valyl-tRNA synthetase signature 369 382 2.0E-35 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 631 7.3E-232 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Gene3D G3DSA:1.10.287.380 877 946 5.5E-23 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 SUPERFAMILY SSF52374 364 571 9.12E-137 T 28-03-2018 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 SUPERFAMILY SSF52374 1 192 9.12E-137 T 28-03-2018 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 SUPERFAMILY SSF52374 609 641 9.12E-137 T 28-03-2018 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 SUPERFAMILY SSF47323 642 899 1.33E-69 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS23405 10b4370b084cfeff55b22caab4254c92 951 Gene3D G3DSA:1.10.730.10 631 816 4.9E-55 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS02690 6967b29e45f4822af0ea570128be0eff 321 Pfam PF00294 pfkB family carbohydrate kinase 19 305 1.4E-48 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS02690 6967b29e45f4822af0ea570128be0eff 321 SUPERFAMILY SSF53613 14 305 2.49E-53 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02690 6967b29e45f4822af0ea570128be0eff 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 53 77 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02690 6967b29e45f4822af0ea570128be0eff 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 263 276 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02690 6967b29e45f4822af0ea570128be0eff 321 Gene3D G3DSA:3.40.1190.20 15 320 3.9E-46 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 SMART SM00065 223 354 0.0032 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 SUPERFAMILY SSF55874 414 551 4.58E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 Pfam PF07694 5TMR of 5TMR-LYT 29 192 4.2E-44 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 SUPERFAMILY SSF55781 226 345 2.35E-9 T 28-03-2018 IPR029016 GAF domain-like WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 Pfam PF06580 Histidine kinase 359 438 2.4E-24 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 Gene3D G3DSA:3.30.450.40 194 335 8.4E-8 T 28-03-2018 IPR029016 GAF domain-like WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 SMART SM00387 452 554 3.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 Pfam PF01590 GAF domain 227 346 8.3E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 Gene3D G3DSA:3.30.565.10 336 552 4.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS01345 76a583a6fe6de5c419680253d272d55d 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 456 552 3.7E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS14170 4d5536277065b20653452dc2630581a8 519 SUPERFAMILY SSF49503 33 166 5.56E-30 T 28-03-2018 IPR008972 Cupredoxin WM46_RS14170 4d5536277065b20653452dc2630581a8 519 SUPERFAMILY SSF49503 495 519 6.68E-36 T 28-03-2018 IPR008972 Cupredoxin WM46_RS14170 4d5536277065b20653452dc2630581a8 519 SUPERFAMILY SSF49503 172 288 6.68E-36 T 28-03-2018 IPR008972 Cupredoxin WM46_RS14170 4d5536277065b20653452dc2630581a8 519 Pfam PF07732 Multicopper oxidase 55 166 4.6E-31 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 WM46_RS14170 4d5536277065b20653452dc2630581a8 519 SUPERFAMILY SSF49503 350 519 1.33E-28 T 28-03-2018 IPR008972 Cupredoxin WM46_RS14170 4d5536277065b20653452dc2630581a8 519 Pfam PF07731 Multicopper oxidase 407 519 2.6E-24 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 WM46_RS14170 4d5536277065b20653452dc2630581a8 519 ProSitePatterns PS00080 Multicopper oxidases signature 2. 502 513 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 WM46_RS14170 4d5536277065b20653452dc2630581a8 519 Gene3D G3DSA:2.60.40.420 170 340 4.3E-23 T 28-03-2018 IPR008972 Cupredoxin WM46_RS14170 4d5536277065b20653452dc2630581a8 519 Gene3D G3DSA:2.60.40.420 345 519 2.1E-34 T 28-03-2018 IPR008972 Cupredoxin WM46_RS14170 4d5536277065b20653452dc2630581a8 519 Pfam PF00394 Multicopper oxidase 224 289 1.3E-4 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 WM46_RS14170 4d5536277065b20653452dc2630581a8 519 Gene3D G3DSA:2.60.40.420 29 169 2.3E-27 T 28-03-2018 IPR008972 Cupredoxin WM46_RS25190 b72f0bf3ea68cec9d8ee2dbcb854fd83 191 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 12 184 2.6E-62 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 WM46_RS25190 b72f0bf3ea68cec9d8ee2dbcb854fd83 191 Gene3D G3DSA:3.20.20.400 3 185 3.1E-65 T 28-03-2018 WM46_RS25190 b72f0bf3ea68cec9d8ee2dbcb854fd83 191 SUPERFAMILY SSF110391 11 185 3.79E-55 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 WM46_RS25190 b72f0bf3ea68cec9d8ee2dbcb854fd83 191 PIRSF PIRSF016897 1 190 9.9E-69 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 19 558 4.7E-299 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 SUPERFAMILY SSF55124 346 422 3.43E-22 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 430 539 0.3 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 331 1.2E-47 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Gene3D G3DSA:3.30.413.10 141 345 7.4E-46 T 28-03-2018 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 353 417 3.1E-15 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 81 138 2.4E-12 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 10 570 58.334 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 477 493 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 SUPERFAMILY SSF56014 150 344 1.7E-61 T 28-03-2018 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 PRINTS PR00397 Sirohaem Fe-binding site signature 429 447 1.5E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 PRINTS PR00397 Sirohaem Fe-binding site signature 477 495 1.5E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 SUPERFAMILY SSF55124 14 142 2.13E-25 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 Gene3D G3DSA:3.30.413.10 425 560 7.6E-25 T 28-03-2018 WM46_RS25215 a2e050763c64230ea2a9e233f132262a 570 SUPERFAMILY SSF56014 428 559 3.01E-34 T 28-03-2018 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 214 2.6E-85 T 28-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 ProSitePatterns PS00958 Transaldolase active site. 82 99 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 Hamap MF_00496 Fructose-6-phosphate aldolase [fsa]. 1 220 49.994 T 28-03-2018 IPR023001 Fructose-6-phosphate aldolase GO:0016832 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 Gene3D G3DSA:3.20.20.70 1 220 3.3E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 SUPERFAMILY SSF51569 1 216 2.56E-62 T 28-03-2018 WM46_RS10305 15e32c3d7316feafbeaa83e9b1ceb3d1 220 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 206 2.1E-43 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 Pfam PF06719 AraC-type transcriptional regulator N-terminus 29 178 9.6E-37 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 SUPERFAMILY SSF46689 191 241 2.44E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 SUPERFAMILY SSF46689 243 292 3.81E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 SMART SM00342 207 290 2.5E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 Gene3D G3DSA:1.10.10.60 248 297 1.7E-12 T 28-03-2018 WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 Pfam PF12833 Helix-turn-helix domain 213 288 2.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS16020 d9d76e148e4c452430521323cc9f564c 299 Gene3D G3DSA:1.10.10.60 24 247 2.9E-14 T 28-03-2018 WM46_RS03155 a9241e462cde3c332ae36f888316edbe 235 SUPERFAMILY SSF47413 8 70 1.22E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS03155 a9241e462cde3c332ae36f888316edbe 235 Gene3D G3DSA:1.10.260.40 10 87 1.4E-11 T 28-03-2018 WM46_RS03155 a9241e462cde3c332ae36f888316edbe 235 SMART SM00530 12 66 6.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS03155 a9241e462cde3c332ae36f888316edbe 235 Pfam PF00717 Peptidase S24-like 144 206 4.5E-11 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS03155 a9241e462cde3c332ae36f888316edbe 235 SUPERFAMILY SSF51306 93 226 7.59E-21 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS03155 a9241e462cde3c332ae36f888316edbe 235 Gene3D G3DSA:2.10.109.10 101 230 2.2E-20 T 28-03-2018 WM46_RS20385 38d832918cd20c541019a21ef5d548f2 108 Pfam PF11742 Protein of unknown function (DUF3302) 3 78 3.2E-42 T 28-03-2018 IPR011223 Uncharacterised conserved protein UCP028770 WM46_RS20385 38d832918cd20c541019a21ef5d548f2 108 PIRSF PIRSF028770 1 107 2.8E-59 T 28-03-2018 IPR011223 Uncharacterised conserved protein UCP028770 WM46_RS17735 059e9230e3dedae588f588de9f9ffaa2 269 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 73 82 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site WM46_RS17735 059e9230e3dedae588f588de9f9ffaa2 269 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 157 167 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site WM46_RS17735 059e9230e3dedae588f588de9f9ffaa2 269 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 21 250 3.7E-83 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 WM46_RS17735 059e9230e3dedae588f588de9f9ffaa2 269 Gene3D G3DSA:1.20.1080.10 2 260 1.3E-60 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS17735 059e9230e3dedae588f588de9f9ffaa2 269 Pfam PF01226 Formate/nitrite transporter 20 247 5.9E-57 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.7E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 Gene3D G3DSA:1.10.10.60 6 44 4.3E-14 T 28-03-2018 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 Gene3D G3DSA:1.10.357.10 67 196 7.1E-10 T 28-03-2018 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 SUPERFAMILY SSF48498 87 192 5.48E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 192 9.2E-76 T 28-03-2018 IPR017757 Transcriptional repressor BetI WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 196 100.765 T 28-03-2018 IPR017757 Transcriptional repressor BetI WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 SUPERFAMILY SSF46689 6 82 9.23E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 87 192 1.9E-28 T 28-03-2018 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS11715 42149081cbc82b13a9ccd5b134cb4ea2 196 Gene3D G3DSA:1.10.260.40 45 66 1.2E-5 T 28-03-2018 WM46_RS08695 c0ef31a1cbfd3d56ee2c14815a30e3ec 358 SUPERFAMILY SSF53659 4 340 3.99E-104 T 28-03-2018 WM46_RS08695 c0ef31a1cbfd3d56ee2c14815a30e3ec 358 Gene3D G3DSA:3.40.718.10 1 340 2.9E-117 T 28-03-2018 WM46_RS08695 c0ef31a1cbfd3d56ee2c14815a30e3ec 358 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 344 142.171 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 WM46_RS08695 c0ef31a1cbfd3d56ee2c14815a30e3ec 358 PIRSF PIRSF002465 2 343 2.7E-128 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 WM46_RS08695 c0ef31a1cbfd3d56ee2c14815a30e3ec 358 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 6 344 6.6E-148 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 WM46_RS08695 c0ef31a1cbfd3d56ee2c14815a30e3ec 358 Pfam PF02504 Fatty acid synthesis protein 5 331 3.4E-129 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 Gene3D G3DSA:3.40.190.10 174 260 9.0E-19 T 28-03-2018 WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 Gene3D G3DSA:3.40.190.10 89 173 4.8E-14 T 28-03-2018 WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 Pfam PF03466 LysR substrate binding domain 90 290 5.5E-39 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 Gene3D G3DSA:1.10.10.10 3 84 8.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 SUPERFAMILY SSF46785 4 108 9.54E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17120 9d5621e4dda36b6956d2b9f2f99d2abb 309 SUPERFAMILY SSF53850 90 292 8.69E-40 T 28-03-2018 WM46_RS20570 56d62c342f06949c637605631399d89e 400 Pfam PF07690 Major Facilitator Superfamily 26 230 4.4E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20570 56d62c342f06949c637605631399d89e 400 SUPERFAMILY SSF103473 7 391 3.79E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20570 56d62c342f06949c637605631399d89e 400 TIGRFAM TIGR00890 2A0111: oxalate/formate antiporter family transporter 9 383 1.3E-137 T 28-03-2018 IPR004741 Oxalate/formate antiporter family transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS20570 56d62c342f06949c637605631399d89e 400 Gene3D G3DSA:1.20.1250.20 203 400 1.2E-20 T 28-03-2018 WM46_RS20570 56d62c342f06949c637605631399d89e 400 Gene3D G3DSA:1.20.1250.20 1 199 7.4E-22 T 28-03-2018 WM46_RS08920 32b31b45d922bac8fab71edfa4ea150a 386 Pfam PF01757 Acyltransferase family 10 357 1.8E-35 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 WM46_RS08920 32b31b45d922bac8fab71edfa4ea150a 386 Hamap MF_01066 Glucans biosynthesis protein C [mdoC]. 2 375 38.308 T 28-03-2018 IPR023723 Glucan biosynthesis protein C GO:0016741 WM46_RS08920 32b31b45d922bac8fab71edfa4ea150a 386 Gene3D G3DSA:1.20.1070.10 16 265 2.4E-4 T 28-03-2018 WM46_RS21875 517b8cd9edce014a5a1c324f1a7e12c8 150 Pfam PF06754 Phosphonate metabolism protein PhnG 7 147 2.3E-52 T 28-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS21875 517b8cd9edce014a5a1c324f1a7e12c8 150 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 6 148 7.5E-52 T 28-03-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 9.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 9.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 9.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 9.9E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Gene3D G3DSA:3.40.50.2300 664 798 1.4E-36 T 28-03-2018 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Pfam PF00512 His Kinase A (phospho-acceptor) domain 293 357 7.9E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Pfam PF01627 Hpt domain 828 908 1.5E-12 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SUPERFAMILY SSF47384 277 358 3.14E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SUPERFAMILY SSF55874 346 516 9.69E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SMART SM00387 404 520 7.9E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Gene3D G3DSA:1.10.287.130 282 353 2.3E-20 T 28-03-2018 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SMART SM00388 292 357 7.5E-25 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Gene3D G3DSA:1.20.120.160 805 918 1.4E-19 T 28-03-2018 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SMART SM00073 819 914 2.6E-21 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Pfam PF00072 Response regulator receiver domain 670 781 3.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Gene3D G3DSA:3.30.565.10 361 527 3.8E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SUPERFAMILY SSF47226 764 777 8.77E-23 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SUPERFAMILY SSF47226 808 909 8.77E-23 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 31 177 3.1E-54 T 28-03-2018 IPR019247 Histidine kinase BarA, N-terminal WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 404 519 6.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SUPERFAMILY SSF158472 200 249 9.42E-5 T 28-03-2018 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SMART SM00304 200 252 4.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SMART SM00448 668 781 3.1E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS25105 b2a7377e0ea3eb0d6ddcb3d7390dfea4 918 SUPERFAMILY SSF52172 668 786 1.85E-35 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS08075 7a36ce568508cb83ad13c0ab5b4011a4 96 Pfam PF11080 Endoribonuclease GhoS 1 91 3.1E-42 T 28-03-2018 IPR022597 Endoribonuclease GhoS GO:0004521 WM46_RS08075 7a36ce568508cb83ad13c0ab5b4011a4 96 ProDom PD066031 YDIZ CYTOPLASMIC STY1786 1 91 1.0E-38 T 28-03-2018 IPR020499 Uncharacterised protein family YdiZ WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 Gene3D G3DSA:3.30.230.10 76 166 2.4E-34 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.8E-30 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 SUPERFAMILY SSF54768 9 75 5.13E-24 T 28-03-2018 WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 34.99 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 74 1.7E-29 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 SUPERFAMILY SSF54211 79 159 3.54E-27 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 1.4E-71 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17460 5e26b9261841fedfc3f886e196ad600b 167 Gene3D G3DSA:3.30.160.20 10 72 4.2E-28 T 28-03-2018 WM46_RS16670 e3987c4003e3590c2894c740eed5baf3 196 SUPERFAMILY SSF53697 3 191 6.27E-51 T 28-03-2018 WM46_RS16670 e3987c4003e3590c2894c740eed5baf3 196 Hamap MF_01157 DnaA initiator-associating protein DiaA [diaA]. 1 196 61.861 T 28-03-2018 IPR023070 DnaA initiator-associating protein WM46_RS16670 e3987c4003e3590c2894c740eed5baf3 196 Gene3D G3DSA:3.40.50.10490 1 196 1.8E-36 T 28-03-2018 WM46_RS16670 e3987c4003e3590c2894c740eed5baf3 196 Pfam PF13580 SIS domain 9 144 3.3E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 184 8.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 7.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 7.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 7.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 Gene3D G3DSA:1.10.10.10 63 191 7.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 SUPERFAMILY SSF46894 130 185 1.63E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS22775 d99006894a82b405c0ccc94f04e54feb 196 SMART SM00421 134 191 8.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 SUPERFAMILY SSF52922 256 411 1.01E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 689 700 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 745 756 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Gene3D G3DSA:3.40.50.970 793 1168 5.5E-105 T 28-03-2018 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 SMART SM00890 622 679 4.1E-29 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Gene3D G3DSA:3.40.920.10 417 624 1.0E-54 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 954 1066 9.2E-9 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 PIRSF PIRSF000159 1 1174 0.0 T 28-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Pfam PF10371 Domain of unknown function 626 678 6.1E-23 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Gene3D G3DSA:3.40.50.970 1 254 6.1E-48 T 28-03-2018 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 SUPERFAMILY SSF52518 2 254 4.71E-72 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 13 243 1.6E-80 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 1 1165 0.0 T 28-03-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Gene3D G3DSA:3.30.70.20 669 791 2.3E-29 T 28-03-2018 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 347 3.8E-15 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 SUPERFAMILY SSF52518 794 1166 5.89E-118 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Gene3D G3DSA:3.40.50.920 255 416 2.7E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Gene3D G3DSA:4.10.780.10 634 668 2.2E-15 T 28-03-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 426 610 1.2E-34 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 SUPERFAMILY SSF54862 665 838 5.86E-23 T 28-03-2018 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 Pfam PF13484 4Fe-4S double cluster binding domain 689 757 8.4E-10 T 28-03-2018 WM46_RS06270 6f78a4a7d8901e25441eba5f67dda7ca 1174 SUPERFAMILY SSF53323 419 668 1.26E-76 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 883 18.409 T 28-03-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 537 549 - T 28-03-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 SUPERFAMILY SSF51621 6 883 0.0 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 Gene3D G3DSA:1.20.1440.90 274 388 1.2E-25 T 28-03-2018 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 709 735 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 577 606 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 245 260 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 386 406 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 535 555 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 1.3E-68 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 28-03-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS20985 0fe4041b303e705bf16f01edc4686c68 883 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 883 3.7E-294 T 28-03-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 WM46_RS00015 c2dd858f95341ff179ef2942f3b83c35 132 Gene3D G3DSA:1.20.5.170 49 114 5.2E-5 T 28-03-2018 WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 Hamap MF_01879 Dipeptide and tripeptide permease B [dtpB]. 3 486 45.917 T 28-03-2018 IPR023778 Amino acid/peptide transporter family, dipeptide/tripeptide permease B WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 SUPERFAMILY SSF103473 292 480 1.83E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 145 157 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 Gene3D G3DSA:1.20.1250.20 2 196 1.7E-22 T 28-03-2018 WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 Gene3D G3DSA:1.20.1250.20 262 482 2.5E-10 T 28-03-2018 WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 9 483 7.3E-190 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 Pfam PF00854 POT family 82 443 4.2E-95 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 WM46_RS20795 68ab6ecc7ecbfb4023debe727b60b5d7 490 SUPERFAMILY SSF103473 10 289 4.19E-22 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 217 236 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 7 405 2.1E-185 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 SUPERFAMILY SSF53383 4 402 2.96E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 Gene3D G3DSA:3.90.1150.10 284 401 4.4E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 Pfam PF00266 Aminotransferase class-V 26 394 1.2E-155 T 28-03-2018 IPR000192 Aminotransferase class V domain WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 Gene3D G3DSA:3.40.640.10 34 283 3.4E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS07830 00e5c6a9eb18a59dcd706a62861b3ffc 406 Hamap MF_01831 Cysteine desulfurase [sufS]. 1 406 75.097 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 WM46_RS08085 53f9335629308b9d035df69027ca42f8 178 Pfam PF14002 YniB-like protein 15 177 2.4E-77 T 28-03-2018 IPR025229 YniB-like protein WM46_RS08085 53f9335629308b9d035df69027ca42f8 178 ProDom PD035714 MEMBRANE REGULATOR YNIB TRANSMEMBRANE YFEABCD YFEE PROBABLE LOCUS ESCHERICHIA ECS2432 1 178 2.0E-74 T 28-03-2018 WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 95 150 2.0E-14 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 Gene3D G3DSA:1.10.60.10 103 149 2.5E-21 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 Gene3D G3DSA:1.10.10.10 25 102 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 SMART SM00529 56 155 1.7E-40 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 SUPERFAMILY SSF47979 95 152 6.28E-15 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 38 92 3.5E-9 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 WM46_RS10375 3c0e49988e8268e300b80f8b1ba7aa08 157 SUPERFAMILY SSF46785 49 117 2.97E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10055 9e67d655591a18b91b8fc7ffcb7a7cba 299 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 135 296 1.0E-60 T 28-03-2018 IPR005642 Lysine exporter LysO WM46_RS10055 9e67d655591a18b91b8fc7ffcb7a7cba 299 Pfam PF03956 Lysine exporter LysO 113 297 7.6E-58 T 28-03-2018 IPR005642 Lysine exporter LysO WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 SUPERFAMILY SSF52374 110 454 1.3E-97 T 28-03-2018 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Pfam PF00750 tRNA synthetases class I (R) 95 446 9.6E-175 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 577 29.144 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Gene3D G3DSA:3.30.1360.70 1 106 8.6E-30 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Gene3D G3DSA:3.40.50.620 107 440 1.5E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Gene3D G3DSA:1.10.730.10 441 577 1.1E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 SUPERFAMILY SSF55190 2 101 1.57E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 SMART SM00836 460 577 2.8E-35 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 SMART SM01016 5 87 9.0E-29 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 122 133 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 6.8E-26 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 6.8E-26 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 6.8E-26 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 6.8E-26 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 87 9.2E-22 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 SUPERFAMILY SSF47323 454 577 3.66E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 3 577 1.3E-214 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 WM46_RS04240 d7f5feb88f07c8356ab637497ff48e0d 577 Pfam PF05746 DALR anticodon binding domain 460 577 9.3E-34 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.2E-6 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.2E-6 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 6.9E-14 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 6.9E-14 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 6.9E-14 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 SUPERFAMILY SSF52317 1 186 1.18E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.8E-37 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00097 Anthranilate synthase component II signature 164 177 4.8E-37 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.8E-37 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.8E-37 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.8E-37 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.8E-37 T 28-03-2018 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 Pfam PF00117 Glutamine amidotransferase class-I 3 185 4.0E-57 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 3.5E-94 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS17700 2615152f3e4e83fa54e8f3da56555a1f 187 Gene3D G3DSA:3.40.50.880 1 187 2.9E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS13185 e19369b1e401b330126bfc8e0aaec508 91 Gene3D G3DSA:3.30.1660.10 21 89 1.7E-16 T 28-03-2018 IPR025543 Dodecin-like WM46_RS13185 e19369b1e401b330126bfc8e0aaec508 91 Pfam PF07338 Protein of unknown function (DUF1471) 40 89 4.1E-13 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS13185 e19369b1e401b330126bfc8e0aaec508 91 SUPERFAMILY SSF159871 2 90 3.53E-21 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 Gene3D G3DSA:1.10.10.10 1 57 7.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 Gene3D G3DSA:3.30.70.920 59 150 2.7E-20 T 28-03-2018 WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 Pfam PF01037 Lrp/AsnC ligand binding domain 76 143 7.9E-18 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 SUPERFAMILY SSF54909 68 152 1.74E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 SMART SM00344 6 113 2.8E-44 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 SUPERFAMILY SSF46785 4 66 5.86E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 4.6E-14 T 28-03-2018 WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.4E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.4E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS19465 fa0c93a8374aa0a0d3ae6ef49335c9a0 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.4E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS11695 5df6a33112d451722ecd4eaf6e21904e 50 PRINTS PR00281 Hok/Gef cell toxic protein family signature 25 47 2.4E-11 T 28-03-2018 IPR000021 Hok/gef cell toxic protein GO:0016020 WM46_RS11695 5df6a33112d451722ecd4eaf6e21904e 50 PRINTS PR00281 Hok/Gef cell toxic protein family signature 5 23 2.4E-11 T 28-03-2018 IPR000021 Hok/gef cell toxic protein GO:0016020 WM46_RS11695 5df6a33112d451722ecd4eaf6e21904e 50 Pfam PF01848 Hok/gef family 5 46 3.0E-17 T 28-03-2018 IPR000021 Hok/gef cell toxic protein GO:0016020 WM46_RS11695 5df6a33112d451722ecd4eaf6e21904e 50 ProDom PD005979 PLASMID MEMBRANE TRANSMEMBRANE POST-SEGREGATION KILLING INHERITANCE ALTERING PERMEABILITY STABLE MAINTENANCE 1 49 1.0E-16 T 28-03-2018 IPR000021 Hok/gef cell toxic protein GO:0016020 WM46_RS11695 5df6a33112d451722ecd4eaf6e21904e 50 ProSitePatterns PS00556 Hok/gef family cell toxic proteins signature. 10 29 - T 28-03-2018 IPR018084 Hok/gef cell toxic protein, conserved site GO:0016020 WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 391 6.7E-117 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 PIRSF PIRSF001434 1 395 8.6E-116 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 SUPERFAMILY SSF53383 25 392 4.92E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 Gene3D G3DSA:3.40.640.10 1 258 2.1E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 8 393 4.6E-169 T 28-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 WM46_RS16010 1f1dba7d091b644934e813ae0611f15e 395 Gene3D G3DSA:3.90.1150.10 259 395 1.0E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS13365 97c21dd3dbd1772c4b0c187826a84688 263 Gene3D G3DSA:3.20.20.60 1 251 2.4E-51 T 28-03-2018 WM46_RS13365 97c21dd3dbd1772c4b0c187826a84688 263 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 240 2.0E-66 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 WM46_RS13365 97c21dd3dbd1772c4b0c187826a84688 263 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 3 250 1.1E-130 T 28-03-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 WM46_RS13365 97c21dd3dbd1772c4b0c187826a84688 263 Hamap MF_01292 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase [hpcH]. 1 263 66.412 T 28-03-2018 IPR023701 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, Enterobacteriales GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 WM46_RS13365 97c21dd3dbd1772c4b0c187826a84688 263 SUPERFAMILY SSF51621 2 249 3.77E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 SUPERFAMILY SSF52540 5 230 2.6E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 Gene3D G3DSA:3.40.50.300 1 236 5.1E-53 T 28-03-2018 WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 SUPERFAMILY SSF52540 260 488 1.81E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 Gene3D G3DSA:3.40.50.300 254 499 1.3E-40 T 28-03-2018 WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 SMART SM00382 30 220 9.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 SMART SM00382 281 484 3.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 Pfam PF00005 ABC transporter 21 172 2.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS25010 71308b26f98d29fd443c53668a00fc2e 499 Pfam PF00005 ABC transporter 272 427 3.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Gene3D G3DSA:3.40.30.10 441 479 5.4E-4 T 28-03-2018 WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Gene3D G3DSA:2.60.40.1250 20 144 1.1E-38 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 SUPERFAMILY SSF52833 449 564 1.4E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Pfam PF11412 Disulphide bond corrector protein DsbC 29 137 1.8E-33 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 567 40.196 T 28-03-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 SUPERFAMILY SSF74863 27 141 5.89E-40 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 ProSitePatterns PS00194 Thioredoxin family active site. 475 493 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Pfam PF13899 Thioredoxin-like 458 540 2.6E-14 T 28-03-2018 WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 175 380 5.5E-19 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 WM46_RS22695 5d9299437f0f5e0fc8accdb99f83d139 568 Gene3D G3DSA:3.40.30.10 480 567 7.8E-14 T 28-03-2018 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Pfam PF17203 Single cache domain 3 49 178 2.8E-21 T 28-03-2018 IPR033463 Single cache domain 3 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Gene3D G3DSA:3.30.450.20 40 181 4.3E-26 T 28-03-2018 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 7.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 535 7.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 516 7.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Gene3D G3DSA:3.30.565.10 387 538 1.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 332 384 3.0E-10 T 28-03-2018 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 436 535 1.3E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Gene3D G3DSA:3.30.450.20 216 330 6.6E-15 T 28-03-2018 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 SUPERFAMILY SSF55874 433 535 1.31E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 SUPERFAMILY SSF103190 46 179 1.26E-39 T 28-03-2018 IPR029151 Periplasmic sensor domain-like WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 SMART SM00387 430 538 1.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 SMART SM00091 222 288 6.9E-5 T 28-03-2018 IPR000014 PAS domain WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Gene3D G3DSA:1.10.287.130 331 386 2.9E-15 T 28-03-2018 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 SUPERFAMILY SSF55785 233 334 1.35E-7 T 28-03-2018 IPR000014 PAS domain WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 SUPERFAMILY SSF55890 339 463 1.44E-16 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 WM46_RS22000 ab7f2a12e31fdf5c4e6d03ac08bfb006 543 Pfam PF00989 PAS fold 222 323 1.6E-13 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS15100 2423d420560e94ff96d2c565bf4fe755 378 Gene3D G3DSA:3.20.20.70 4 317 1.0E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS15100 2423d420560e94ff96d2c565bf4fe755 378 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 368 2.9E-140 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 WM46_RS15100 2423d420560e94ff96d2c565bf4fe755 378 Pfam PF06969 HemN C-terminal domain 306 364 3.2E-8 T 28-03-2018 IPR010723 HemN, C-terminal WM46_RS15100 2423d420560e94ff96d2c565bf4fe755 378 SUPERFAMILY SSF102114 5 376 8.37E-108 T 28-03-2018 WM46_RS15100 2423d420560e94ff96d2c565bf4fe755 378 Pfam PF04055 Radical SAM superfamily 11 179 8.0E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS15100 2423d420560e94ff96d2c565bf4fe755 378 SMART SM00729 6 223 1.0E-52 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 PIRSF PIRSF000398 1 272 1.1E-72 T 28-03-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 Gene3D G3DSA:3.40.50.150 154 269 3.7E-18 T 28-03-2018 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 TIGRFAM TIGR00571 dam: DNA adenine methylase 5 267 7.4E-103 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 SUPERFAMILY SSF53335 5 267 1.05E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 10 26 2.9E-19 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 2.9E-19 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 2.9E-19 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 2.9E-19 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 10 250 1.7E-75 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 WM46_RS17765 acbaee1277c0a8adccd4ae096862c324 278 Gene3D G3DSA:1.10.1020.10 57 153 1.1E-34 T 28-03-2018 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 139 4.6E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 5.6E-29 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 75 90 5.6E-29 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 97 110 5.6E-29 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 113 128 5.6E-29 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 41 57 5.6E-29 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 Gene3D G3DSA:3.40.50.2300 3 148 2.5E-42 T 28-03-2018 WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 SMART SM00226 3 141 4.7E-60 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily WM46_RS02800 666873509bc73409e479a9d8bdd86e63 148 SUPERFAMILY SSF52788 1 142 4.84E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 Gene3D G3DSA:2.40.30.10 203 269 5.1E-23 T 28-03-2018 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 Gene3D G3DSA:1.10.8.260 270 321 8.4E-15 T 28-03-2018 IPR023166 HI0933 insert-like domain WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 SUPERFAMILY SSF51905 3 188 7.28E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 SUPERFAMILY SSF51905 337 396 7.28E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 Pfam PF03486 HI0933-like protein 5 392 2.1E-156 T 28-03-2018 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 Gene3D G3DSA:3.50.50.60 1 202 2.1E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 2.1E-7 T 28-03-2018 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 362 369 2.1E-7 T 28-03-2018 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.1E-7 T 28-03-2018 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 SUPERFAMILY SSF160996 190 338 1.2E-43 T 28-03-2018 WM46_RS20815 c847abe898759b60a9aee1ecbb405ecf 397 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 392 6.8E-128 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like WM46_RS23100 ba93fd3b098c4cc06501322e5e4e9432 355 Gene3D G3DSA:3.30.360.10 157 354 3.4E-25 T 28-03-2018 WM46_RS23100 ba93fd3b098c4cc06501322e5e4e9432 355 Gene3D G3DSA:3.40.50.720 27 156 7.1E-18 T 28-03-2018 WM46_RS23100 ba93fd3b098c4cc06501322e5e4e9432 355 SUPERFAMILY SSF51735 46 168 8.44E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23100 ba93fd3b098c4cc06501322e5e4e9432 355 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 48 143 7.9E-7 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS23100 ba93fd3b098c4cc06501322e5e4e9432 355 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 157 230 1.5E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS23100 ba93fd3b098c4cc06501322e5e4e9432 355 SUPERFAMILY SSF55347 155 327 1.96E-23 T 28-03-2018 WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 2.8E-21 T 28-03-2018 WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 Gene3D G3DSA:1.10.10.10 8 63 6.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 Pfam PF01037 Lrp/AsnC ligand binding domain 78 152 6.0E-25 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 SUPERFAMILY SSF54909 74 157 2.68E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 SUPERFAMILY SSF46785 12 70 4.01E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 Gene3D G3DSA:3.30.70.920 64 158 1.0E-27 T 28-03-2018 WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 SMART SM00344 12 121 2.1E-55 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 6.2E-23 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 6.2E-23 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS09945 31552388ae2bc68bbd1b4365e3e3d017 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 6.2E-23 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS07460 a1a414b5b5e832f9d47c3aca45249291 232 PIRSF PIRSF006102 1 218 2.9E-78 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 WM46_RS07460 a1a414b5b5e832f9d47c3aca45249291 232 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 199 1.9E-61 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 WM46_RS07460 a1a414b5b5e832f9d47c3aca45249291 232 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 210 27.426 T 28-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 WM46_RS07460 a1a414b5b5e832f9d47c3aca45249291 232 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 7 209 8.3E-81 T 28-03-2018 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 SUPERFAMILY SSF100950 74 238 1.94E-26 T 28-03-2018 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.0E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.0E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 SUPERFAMILY SSF46785 4 62 3.86E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 SMART SM01134 73 236 7.2E-63 T 28-03-2018 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 Gene3D G3DSA:3.40.50.1360 66 241 9.3E-34 T 28-03-2018 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 SMART SM00420 6 58 5.7E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 Pfam PF00455 DeoR C terminal sensor domain 75 234 1.6E-48 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.5E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS10940 faf50ccfce05a05c19cced1117908134 268 Gene3D G3DSA:1.10.10.10 2 58 2.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12540 f0298bf8b8ec035253c762c0f6097c25 129 Gene3D G3DSA:1.10.10.10 28 129 1.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12540 f0298bf8b8ec035253c762c0f6097c25 129 SUPERFAMILY SSF46767 31 113 1.2E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS12540 f0298bf8b8ec035253c762c0f6097c25 129 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 33 112 1.7E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS12540 f0298bf8b8ec035253c762c0f6097c25 129 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 33 101 3.1E-14 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS18815 a228340cb514d836f89ee933994946e2 472 Gene3D G3DSA:1.20.1250.20 8 223 8.3E-12 T 28-03-2018 WM46_RS18815 a228340cb514d836f89ee933994946e2 472 SUPERFAMILY SSF103473 17 440 3.66E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS18815 a228340cb514d836f89ee933994946e2 472 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 16 451 4.0E-156 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS18815 a228340cb514d836f89ee933994946e2 472 Gene3D G3DSA:1.20.1250.20 224 440 8.7E-19 T 28-03-2018 WM46_RS18815 a228340cb514d836f89ee933994946e2 472 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 67 94 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 WM46_RS18815 a228340cb514d836f89ee933994946e2 472 Pfam PF13347 MFS/sugar transport protein 18 438 1.7E-82 T 28-03-2018 WM46_RS15200 399362e0d228bae7e54214eb2c10c611 118 SUPERFAMILY SSF46785 7 105 2.78E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15200 399362e0d228bae7e54214eb2c10c611 118 Gene3D G3DSA:1.10.10.10 17 116 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15200 399362e0d228bae7e54214eb2c10c611 118 Pfam PF01638 HxlR-like helix-turn-helix 20 105 1.7E-33 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 Gene3D G3DSA:2.40.128.130 534 856 5.1E-56 T 28-03-2018 WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 148 193 1.9E-7 T 28-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 Pfam PF03797 Autotransporter beta-domain 579 834 3.5E-53 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 Gene3D G3DSA:2.160.20.20 5 508 3.3E-39 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 SUPERFAMILY SSF103515 542 856 3.66E-53 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 404 856 6.2E-123 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 322 352 2.1E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 SMART SM00869 576 845 1.3E-46 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 Pfam PF12951 Passenger-associated-transport-repeat 325 350 6.0E-7 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 SUPERFAMILY SSF51126 42 509 5.34E-35 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS07205 8c463515ce77367871c64c75e5fa57c6 856 Pfam PF03212 Pertactin 383 502 2.0E-11 T 28-03-2018 IPR004899 Pertactin, central region WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 8 35 1.1E-50 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 1.1E-50 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 1.1E-50 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 1.1E-50 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 ProSitePatterns PS01218 TatC family signature. 154 173 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 241 18.239 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 221 2.0E-67 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18990 65b90d5ff59045a0b477cb37f3218b7b 263 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 226 1.6E-80 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 WM46_RS18120 5039d2495518426e1baee82489a3cb02 425 Gene3D G3DSA:1.10.3470.10 95 401 9.5E-47 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS18120 5039d2495518426e1baee82489a3cb02 425 Pfam PF02653 Branched-chain amino acid transport system / permease component 112 398 7.8E-60 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS18120 5039d2495518426e1baee82489a3cb02 425 Pfam PF11862 Domain of unknown function (DUF3382) 6 103 3.6E-24 T 28-03-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 SUPERFAMILY SSF118215 18 400 2.88E-94 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 PRINTS PR00173 Glutamate-aspartate symporter signature 18 38 4.1E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 4.1E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 4.1E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 4.1E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 4.1E-13 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 Gene3D G3DSA:1.10.3860.10 7 407 1.7E-73 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 Pfam PF00375 Sodium:dicarboxylate symporter family 18 397 5.4E-63 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS16385 c603608d20e066e50dfbed513ee66cca 414 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 6 407 35.943 T 28-03-2018 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 SUPERFAMILY SSF52540 275 525 5.09E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 265 2.0E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 Pfam PF00005 ABC transporter 26 184 9.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 Pfam PF00005 ABC transporter 303 454 6.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 Gene3D G3DSA:3.40.50.300 2 268 8.8E-68 T 28-03-2018 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 Gene3D G3DSA:3.40.50.300 272 528 9.5E-73 T 28-03-2018 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 SMART SM00382 34 234 2.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 SMART SM00382 311 502 7.9E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02280 56ad5d0fe941e756d7085b827c14542b 529 SUPERFAMILY SSF52540 5 256 5.89E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24880 849ffb956f4deb03732d5c6389d6f33b 156 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS24880 849ffb956f4deb03732d5c6389d6f33b 156 SUPERFAMILY SSF54523 8 124 3.85E-6 T 28-03-2018 WM46_RS24880 849ffb956f4deb03732d5c6389d6f33b 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 19 4.2E-4 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS24880 849ffb956f4deb03732d5c6389d6f33b 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 20 1.8E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 Pfam PF03797 Autotransporter beta-domain 593 847 1.1E-50 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 SUPERFAMILY SSF103515 553 869 1.31E-51 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 417 869 1.0E-116 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 Gene3D G3DSA:2.160.20.20 15 523 3.4E-54 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 SUPERFAMILY SSF51126 79 527 9.1E-32 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 Gene3D G3DSA:2.40.128.130 548 869 2.4E-53 T 28-03-2018 WM46_RS08445 d38abdc7dabf7816355b5411ae07d3f1 869 SMART SM00869 590 858 4.0E-44 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Pfam PF00583 Acetyltransferase (GNAT) family 759 863 7.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 SUPERFAMILY SSF56059 481 686 2.43E-26 T 28-03-2018 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Gene3D G3DSA:3.40.50.261 127 284 1.4E-39 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 SUPERFAMILY SSF52210 125 286 1.7E-35 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Gene3D G3DSA:3.40.50.261 285 452 4.9E-34 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Gene3D G3DSA:3.40.630.30 716 886 5.9E-24 T 28-03-2018 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Gene3D G3DSA:3.30.1490.20 500 561 6.7E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 SMART SM00881 9 104 7.5E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 280 3.5E-46 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 SUPERFAMILY SSF52210 287 447 6.93E-38 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Pfam PF13549 ATP-grasp domain 472 694 4.1E-72 T 28-03-2018 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Gene3D G3DSA:3.30.470.20 562 696 5.0E-23 T 28-03-2018 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Pfam PF13380 CoA binding domain 13 129 2.4E-22 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 SUPERFAMILY SSF51735 2 136 5.58E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 SUPERFAMILY SSF55729 615 866 1.06E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS00320 de4c1ce12aafbd0d12fafd36aaa9cb9b 886 Gene3D G3DSA:3.40.50.720 9 126 1.9E-30 T 28-03-2018 WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 Gene3D G3DSA:1.20.1600.10 189 330 5.8E-16 T 28-03-2018 WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 Pfam PF00529 HlyD membrane-fusion protein of T1SS 41 352 3.4E-9 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 SUPERFAMILY SSF111369 202 303 1.31E-11 T 28-03-2018 WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 Gene3D G3DSA:2.40.50.100 60 132 1.3E-14 T 28-03-2018 WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 SUPERFAMILY SSF111369 133 191 9.68E-5 T 28-03-2018 WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 303 6.3E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS06335 9224824d4a5b399f1f942d5906cb1a8d 360 SUPERFAMILY SSF111369 62 120 2.35E-10 T 28-03-2018 WM46_RS02315 8c5adbbe6449d2e19aaa7dbfb4d366be 237 Pfam PF01569 PAP2 superfamily 135 207 1.1E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS02315 8c5adbbe6449d2e19aaa7dbfb4d366be 237 Gene3D G3DSA:1.20.144.10 7 225 2.9E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS02315 8c5adbbe6449d2e19aaa7dbfb4d366be 237 SMART SM00014 94 210 5.6E-20 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS02315 8c5adbbe6449d2e19aaa7dbfb4d366be 237 Hamap MF_01945 Lipid A 1-diphosphate synthase [lpxT]. 1 233 42.074 T 28-03-2018 IPR032908 Lipid A 1-diphosphate synthase GO:0005886|GO:0043165|GO:0050380 WM46_RS02315 8c5adbbe6449d2e19aaa7dbfb4d366be 237 SUPERFAMILY SSF48317 5 221 6.41E-32 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 398 628 4.0E-79 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 SUPERFAMILY SSF51230 205 296 3.01E-23 T 28-03-2018 IPR011053 Single hybrid motif WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 SUPERFAMILY SSF51230 1 94 2.22E-23 T 28-03-2018 IPR011053 Single hybrid motif WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Pfam PF02817 e3 binding domain 325 360 2.1E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 SUPERFAMILY SSF47005 319 364 3.92E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Gene3D G3DSA:3.30.559.10 385 629 3.4E-79 T 28-03-2018 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Gene3D G3DSA:2.40.50.100 248 321 1.1E-8 T 28-03-2018 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 128 157 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 SUPERFAMILY SSF52777 387 628 4.45E-80 T 28-03-2018 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 228 257 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Gene3D G3DSA:4.10.320.10 322 379 5.6E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 SUPERFAMILY SSF51230 105 197 1.7E-23 T 28-03-2018 IPR011053 Single hybrid motif WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 187 629 3.4E-227 T 28-03-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Pfam PF00364 Biotin-requiring enzyme 4 73 4.8E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Pfam PF00364 Biotin-requiring enzyme 207 276 5.8E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Pfam PF00364 Biotin-requiring enzyme 106 176 7.4E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Gene3D G3DSA:3.90.1170.30 147 247 7.9E-23 T 28-03-2018 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Gene3D G3DSA:3.90.1170.30 44 146 4.8E-23 T 28-03-2018 WM46_RS14255 2250ba7632bd4df715ba73fb74230ca9 629 Gene3D G3DSA:3.90.1170.30 1 43 3.3E-9 T 28-03-2018 WM46_RS21375 b832710f215b4b20d951bd175439c952 229 Pfam PF03575 Peptidase family S51 3 204 2.0E-60 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 WM46_RS21375 b832710f215b4b20d951bd175439c952 229 Gene3D G3DSA:3.40.50.880 1 229 6.2E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS21375 b832710f215b4b20d951bd175439c952 229 SUPERFAMILY SSF52317 1 220 5.8E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS21375 b832710f215b4b20d951bd175439c952 229 Hamap MF_00510 Peptidase E [pepE]. 1 215 48.932 T 28-03-2018 IPR023172 Peptidase S51, dipeptidase E GO:0016805 WM46_RS19885 3806c214c71998903de81a7447dce913 459 Pfam PF02264 LamB porin 82 459 3.3E-79 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS19885 3806c214c71998903de81a7447dce913 459 Gene3D G3DSA:2.40.170.10 80 459 1.4E-79 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS19885 3806c214c71998903de81a7447dce913 459 SUPERFAMILY SSF56935 80 459 1.24E-91 T 28-03-2018 WM46_RS19885 3806c214c71998903de81a7447dce913 459 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 365 426 0.002 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS19885 3806c214c71998903de81a7447dce913 459 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 108 207 5.0E-49 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 6.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 Gene3D G3DSA:1.10.357.10 63 224 1.5E-40 T 28-03-2018 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 Gene3D G3DSA:1.10.357.10 47 62 0.012 T 28-03-2018 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 Pfam PF09209 Domain of unknown function (DUF1956) 96 218 7.9E-38 T 28-03-2018 IPR015292 Transcription regulator YbiH, C-terminal WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 Gene3D G3DSA:1.10.10.60 1 46 1.7E-16 T 28-03-2018 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 SUPERFAMILY SSF46689 3 81 6.67E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS10490 a62a508d30a9b59fd286d7ce9aef8724 224 SUPERFAMILY SSF48498 91 219 1.11E-37 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS12280 8b01dfaa37fe169c9b428eb255cf6565 259 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 245 2.8E-82 T 28-03-2018 IPR005226 UPF0014 family WM46_RS12280 8b01dfaa37fe169c9b428eb255cf6565 259 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 6 251 1.1E-108 T 28-03-2018 IPR005226 UPF0014 family WM46_RS17235 6fd95b21ff31ef6983a5f63a7cc556b6 483 Pfam PF00474 Sodium:solute symporter family 36 432 1.8E-139 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS17235 6fd95b21ff31ef6983a5f63a7cc556b6 483 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 4 470 2.5E-229 T 28-03-2018 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0031402|GO:0071436 WM46_RS17235 6fd95b21ff31ef6983a5f63a7cc556b6 483 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 414 434 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS17235 6fd95b21ff31ef6983a5f63a7cc556b6 483 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 36 432 2.6E-113 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS17235 6fd95b21ff31ef6983a5f63a7cc556b6 483 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 155 180 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS25790 403536e9da2b5113ca206cea121a0318 507 Pfam PF00563 EAL domain 251 486 1.0E-63 T 28-03-2018 IPR001633 EAL domain WM46_RS25790 403536e9da2b5113ca206cea121a0318 507 Gene3D G3DSA:3.20.20.450 244 502 2.0E-78 T 28-03-2018 IPR001633 EAL domain WM46_RS25790 403536e9da2b5113ca206cea121a0318 507 Pfam PF12792 CSS motif domain associated with EAL 38 219 1.9E-17 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain WM46_RS25790 403536e9da2b5113ca206cea121a0318 507 SMART SM00052 245 491 1.2E-103 T 28-03-2018 IPR001633 EAL domain WM46_RS25790 403536e9da2b5113ca206cea121a0318 507 SUPERFAMILY SSF141868 250 499 4.32E-75 T 28-03-2018 IPR001633 EAL domain WM46_RS09850 86f27741928648083af90c2fa111b927 557 Gene3D G3DSA:2.40.50.140 1 92 1.5E-7 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SUPERFAMILY SSF50249 429 535 2.29E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09850 86f27741928648083af90c2fa111b927 557 PIRSF PIRSF002111 1 534 1.4E-220 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 155 175 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 330 348 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 21 39 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 126 143 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 212 233 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 290 309 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 39 53 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 108 124 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 PRINTS PR00681 Ribosomal protein S1 signature 84 103 2.3E-99 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Pfam PF00575 S1 RNA binding domain 104 171 8.3E-10 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Pfam PF00575 S1 RNA binding domain 275 347 2.7E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Pfam PF00575 S1 RNA binding domain 449 520 7.4E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Pfam PF00575 S1 RNA binding domain 190 260 2.4E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Pfam PF00575 S1 RNA binding domain 361 434 9.5E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Pfam PF00575 S1 RNA binding domain 20 78 2.1E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS09850 86f27741928648083af90c2fa111b927 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 2.2E-240 T 28-03-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SUPERFAMILY SSF50249 255 367 1.0E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09850 86f27741928648083af90c2fa111b927 557 Gene3D G3DSA:2.40.50.140 182 266 2.5E-26 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Gene3D G3DSA:2.40.50.140 361 435 2.3E-20 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Gene3D G3DSA:2.40.50.140 274 348 2.5E-27 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SUPERFAMILY SSF50249 189 277 3.88E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09850 86f27741928648083af90c2fa111b927 557 SUPERFAMILY SSF50249 1 112 2.06E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09850 86f27741928648083af90c2fa111b927 557 SUPERFAMILY SSF50249 106 185 3.28E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09850 86f27741928648083af90c2fa111b927 557 Gene3D G3DSA:2.40.50.140 451 550 2.8E-19 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 Gene3D G3DSA:2.40.50.140 105 178 2.7E-7 T 28-03-2018 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SMART SM00316 190 260 2.8E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SMART SM00316 19 87 1.2E-4 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SMART SM00316 275 347 2.2E-27 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SMART SM00316 362 434 3.4E-21 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SMART SM00316 103 171 2.0E-8 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SMART SM00316 449 520 1.0E-20 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS09850 86f27741928648083af90c2fa111b927 557 SUPERFAMILY SSF50249 347 439 5.67E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS10065 189fd692749413d1af086ff673a649a3 322 Pfam PF00970 Oxidoreductase FAD-binding domain 36 104 6.9E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 SUPERFAMILY SSF63380 9 105 6.81E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 Gene3D G3DSA:3.40.50.80 105 223 5.8E-19 T 28-03-2018 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 Gene3D G3DSA:3.10.20.30 224 322 3.0E-21 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS10065 189fd692749413d1af086ff673a649a3 322 SUPERFAMILY SSF52343 95 220 9.82E-25 T 28-03-2018 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 SUPERFAMILY SSF54292 221 321 4.46E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 115 134 5.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 197 205 5.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 55 69 5.3E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 Gene3D G3DSA:2.40.30.10 8 104 2.6E-17 T 28-03-2018 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 Pfam PF00175 Oxidoreductase NAD-binding domain 116 210 8.6E-9 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM46_RS10065 189fd692749413d1af086ff673a649a3 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 249 315 4.3E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 Gene3D G3DSA:1.10.150.170 112 215 2.7E-37 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 PIRSF PIRSF004486 1 312 1.7E-103 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 Pfam PF01795 MraW methylase family 4 310 1.3E-122 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 SUPERFAMILY SSF53335 7 113 2.23E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 SUPERFAMILY SSF53335 213 310 2.23E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 SUPERFAMILY SSF81799 114 213 1.96E-35 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 311 39.307 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS14420 bd4845d2f1eac446f7e7b25230b8e5ea 313 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 1 310 3.1E-134 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS10280 6b9812fdec66fabd0d51ac58a49669c9 512 Gene3D G3DSA:3.90.76.10 37 181 3.9E-41 T 28-03-2018 WM46_RS10280 6b9812fdec66fabd0d51ac58a49669c9 512 PIRSF PIRSF002741 12 511 1.9E-109 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS10280 6b9812fdec66fabd0d51ac58a49669c9 512 SUPERFAMILY SSF53850 30 511 1.5E-145 T 28-03-2018 WM46_RS10280 6b9812fdec66fabd0d51ac58a49669c9 512 Gene3D G3DSA:3.10.105.10 275 486 2.3E-60 T 28-03-2018 WM46_RS10280 6b9812fdec66fabd0d51ac58a49669c9 512 Gene3D G3DSA:3.40.190.10 182 274 5.5E-28 T 28-03-2018 WM46_RS10280 6b9812fdec66fabd0d51ac58a49669c9 512 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 429 2.1E-99 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS22475 95b676e3ebaa0d4686961f7262a6cad6 439 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 226 330 1.9E-12 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM46_RS22475 95b676e3ebaa0d4686961f7262a6cad6 439 SUPERFAMILY SSF54534 234 437 2.36E-31 T 28-03-2018 WM46_RS22475 95b676e3ebaa0d4686961f7262a6cad6 439 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 349 434 3.1E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM46_RS22475 95b676e3ebaa0d4686961f7262a6cad6 439 Gene3D G3DSA:3.10.50.40 321 439 2.9E-24 T 28-03-2018 WM46_RS22475 95b676e3ebaa0d4686961f7262a6cad6 439 Gene3D G3DSA:1.10.287.460 219 320 3.3E-13 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM46_RS05200 9b1096e75e0eede4dc0c5cbc6ad50dd9 244 Hamap MF_01457 Flagellar brake protein YcgR [ycgR]. 3 239 30.208 T 28-03-2018 IPR023787 Type III secretion system flagellar brake protein YcgR GO:0035438|GO:0071945 WM46_RS05200 9b1096e75e0eede4dc0c5cbc6ad50dd9 244 Gene3D G3DSA:2.30.110.10 9 110 9.0E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS05200 9b1096e75e0eede4dc0c5cbc6ad50dd9 244 Gene3D G3DSA:2.40.10.220 111 244 3.3E-17 T 28-03-2018 WM46_RS05200 9b1096e75e0eede4dc0c5cbc6ad50dd9 244 Pfam PF07238 PilZ domain 112 230 3.6E-10 T 28-03-2018 IPR009875 PilZ domain GO:0035438 WM46_RS05200 9b1096e75e0eede4dc0c5cbc6ad50dd9 244 Pfam PF07317 Flagellar regulator YcgR 8 109 4.8E-29 T 28-03-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal WM46_RS24650 8569549a908e5dc0e191a5d0c031aafa 839 Pfam PF13954 PapC N-terminal domain 44 190 7.9E-43 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS24650 8569549a908e5dc0e191a5d0c031aafa 839 Pfam PF13953 PapC C-terminal domain 757 822 1.7E-14 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS24650 8569549a908e5dc0e191a5d0c031aafa 839 Pfam PF00577 Outer membrane usher protein 204 747 2.4E-185 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS24650 8569549a908e5dc0e191a5d0c031aafa 839 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 314 324 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS24650 8569549a908e5dc0e191a5d0c031aafa 839 SUPERFAMILY SSF141729 69 181 1.1E-31 T 28-03-2018 WM46_RS18105 5e578da4bc4bfd3ce748981cd833126b 439 Pfam PF13416 Bacterial extracellular solute-binding protein 44 367 2.2E-42 T 28-03-2018 WM46_RS18105 5e578da4bc4bfd3ce748981cd833126b 439 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 140 157 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 WM46_RS18105 5e578da4bc4bfd3ce748981cd833126b 439 Gene3D G3DSA:3.40.190.10 141 435 7.4E-45 T 28-03-2018 WM46_RS18105 5e578da4bc4bfd3ce748981cd833126b 439 SUPERFAMILY SSF53850 25 425 2.33E-75 T 28-03-2018 WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 Pfam PF13353 4Fe-4S single cluster domain 111 176 7.4E-6 T 28-03-2018 WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 TIGRFAM TIGR00238 TIGR00238: KamA family protein 3 328 1.2E-149 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 Gene3D G3DSA:3.20.20.70 101 329 1.3E-20 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 15 335 2.9E-158 T 28-03-2018 IPR022462 Lysine-2,3-aminomutase-like WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 PIRSF PIRSF004911 1 342 4.9E-123 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 SUPERFAMILY SSF102114 102 324 3.4E-26 T 28-03-2018 WM46_RS22755 65521f4524cfc0247fafbe13400537bf 342 Pfam PF04055 Radical SAM superfamily 118 263 4.3E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS17145 a2a853e2d472fa9360182d4c7ca123bb 1266 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 2 1262 0.0 T 28-03-2018 IPR011836 Conserved hypothetical protein CHP02099 WM46_RS17145 a2a853e2d472fa9360182d4c7ca123bb 1266 Pfam PF13116 Protein of unknown function 505 789 6.3E-96 T 28-03-2018 IPR025263 Domain of unknown function DUF3971 WM46_RS17145 a2a853e2d472fa9360182d4c7ca123bb 1266 Pfam PF13502 AsmA-like C-terminal region 1010 1252 2.9E-62 T 28-03-2018 IPR032712 AsmA-like, C-terminal WM46_RS07220 862518765ee684f16bfee0773a861161 205 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 4 163 2.4E-80 T 28-03-2018 IPR014297 Dimethylsulphoxide reductase, chain B WM46_RS07220 862518765ee684f16bfee0773a861161 205 Pfam PF12800 4Fe-4S binding domain 12 25 0.0027 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS07220 862518765ee684f16bfee0773a861161 205 SUPERFAMILY SSF54862 3 199 9.0E-71 T 28-03-2018 WM46_RS07220 862518765ee684f16bfee0773a861161 205 Gene3D G3DSA:3.30.70.20 3 80 2.0E-18 T 28-03-2018 WM46_RS07220 862518765ee684f16bfee0773a861161 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07220 862518765ee684f16bfee0773a861161 205 Gene3D G3DSA:3.30.70.20 81 118 9.6E-21 T 28-03-2018 WM46_RS07220 862518765ee684f16bfee0773a861161 205 Gene3D G3DSA:3.30.70.20 119 202 4.1E-18 T 28-03-2018 WM46_RS07220 862518765ee684f16bfee0773a861161 205 Pfam PF13247 4Fe-4S dicluster domain 59 153 1.8E-28 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS12800 4d6c3dea42fdcf798a0a03d16f06732e 121 SUPERFAMILY SSF54593 5 120 4.16E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS12800 4d6c3dea42fdcf798a0a03d16f06732e 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 2.1E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM46_RS12800 4d6c3dea42fdcf798a0a03d16f06732e 121 Gene3D G3DSA:3.10.180.10 5 121 1.4E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS22915 8e1aa7122ba5eb2ca123cdfad64e4448 141 Pfam PF02082 Transcriptional regulator 2 82 1.8E-23 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type WM46_RS22915 8e1aa7122ba5eb2ca123cdfad64e4448 141 Hamap MF_01177 HTH-type transcriptional repressor NsrR [nsrR]. 1 141 44.439 T 28-03-2018 IPR023761 Transcriptional repressor HTH, NsrR GO:0045892 WM46_RS22915 8e1aa7122ba5eb2ca123cdfad64e4448 141 Gene3D G3DSA:1.10.10.10 1 136 7.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22915 8e1aa7122ba5eb2ca123cdfad64e4448 141 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 128 2.6E-35 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type WM46_RS22915 8e1aa7122ba5eb2ca123cdfad64e4448 141 SUPERFAMILY SSF46785 2 131 3.78E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05210 7e2aaa7a6811718e531cdca0bca98913 703 Gene3D G3DSA:2.170.130.10 25 173 9.8E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS05210 7e2aaa7a6811718e531cdca0bca98913 703 Pfam PF00593 TonB dependent receptor 242 702 6.5E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS05210 7e2aaa7a6811718e531cdca0bca98913 703 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 60 703 3.4E-100 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS05210 7e2aaa7a6811718e531cdca0bca98913 703 SUPERFAMILY SSF56935 26 703 6.54E-120 T 28-03-2018 WM46_RS05210 7e2aaa7a6811718e531cdca0bca98913 703 Gene3D G3DSA:2.40.170.20 174 703 4.0E-77 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS05210 7e2aaa7a6811718e531cdca0bca98913 703 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 160 8.7E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS20125 4267f51a8f92f8b8643a86fdac3ead4b 198 Gene3D G3DSA:1.10.357.10 9 198 1.2E-28 T 28-03-2018 WM46_RS20125 4267f51a8f92f8b8643a86fdac3ead4b 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS20125 4267f51a8f92f8b8643a86fdac3ead4b 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 61 5.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS20125 4267f51a8f92f8b8643a86fdac3ead4b 198 SUPERFAMILY SSF46689 5 84 5.49E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS20125 4267f51a8f92f8b8643a86fdac3ead4b 198 Hamap MF_01839 Nucleoid occlusion factor SlmA [slmA]. 1 198 40.844 T 28-03-2018 IPR023769 Nucleoid occlusion factor SlmA GO:0010974 WM46_RS20125 4267f51a8f92f8b8643a86fdac3ead4b 198 SUPERFAMILY SSF48498 83 192 5.78E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 Pfam PF00149 Calcineurin-like phosphoesterase 24 252 1.1E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 SUPERFAMILY SSF56300 22 326 1.12E-72 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 SUPERFAMILY SSF55816 325 512 3.4E-53 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 PRINTS PR01607 Apyrase family signature 21 39 1.7E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 PRINTS PR01607 Apyrase family signature 449 468 1.7E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 PRINTS PR01607 Apyrase family signature 200 217 1.7E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 PRINTS PR01607 Apyrase family signature 235 258 1.7E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 PRINTS PR01607 Apyrase family signature 379 402 1.7E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 Gene3D G3DSA:3.90.780.10 328 517 2.0E-55 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 Gene3D G3DSA:3.60.21.10 17 327 2.9E-74 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS00470 817c4efa433cd51e9d184e0bc8876d20 517 Pfam PF02872 5'-nucleotidase, C-terminal domain 337 475 2.9E-39 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 SUPERFAMILY SSF52540 141 391 7.38E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 ProSitePatterns PS00674 AAA-protein family signature. 291 309 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 615 37.479 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 SUPERFAMILY SSF140990 402 602 6.28E-73 T 28-03-2018 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 188 320 6.4E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 Pfam PF06480 FtsH Extracellular 5 93 4.7E-17 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 Gene3D G3DSA:3.40.50.300 128 331 4.2E-63 T 28-03-2018 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 Pfam PF01434 Peptidase family M41 382 591 1.1E-82 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 Gene3D G3DSA:1.10.8.60 332 411 3.2E-25 T 28-03-2018 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 100 593 5.6E-248 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 WM46_RS16815 d9dc86738b27271303d66219bed75bb9 643 SMART SM00382 184 323 1.9E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25575 3552a9b695712d066173b4a674c68796 142 Pfam PF09335 SNARE associated Golgi protein 25 133 7.9E-11 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS25575 3552a9b695712d066173b4a674c68796 142 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 40 111 0.007 T 28-03-2018 IPR020143 Uncharacterised protein family, RP436 WM46_RS01630 1472f5ff3d2cca0099e3231d0b241a2f 235 SUPERFAMILY SSF161098 17 224 1.31E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01630 1472f5ff3d2cca0099e3231d0b241a2f 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 224 4.1E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01630 1472f5ff3d2cca0099e3231d0b241a2f 235 Gene3D G3DSA:1.10.3720.10 6 233 4.4E-32 T 28-03-2018 WM46_RS01630 1472f5ff3d2cca0099e3231d0b241a2f 235 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 122 4.9E-13 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 SUPERFAMILY SSF63411 248 433 8.5E-26 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Gene3D G3DSA:3.30.830.10 24 241 1.2E-50 T 28-03-2018 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Gene3D G3DSA:3.30.830.10 245 433 1.4E-22 T 28-03-2018 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 SUPERFAMILY SSF63411 26 230 6.63E-49 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Pfam PF05193 Peptidase M16 inactive domain 191 366 2.4E-21 T 28-03-2018 IPR007863 Peptidase M16, C-terminal WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Pfam PF05193 Peptidase M16 inactive domain 634 805 1.7E-14 T 28-03-2018 IPR007863 Peptidase M16, C-terminal WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Gene3D G3DSA:3.30.830.10 691 880 4.6E-24 T 28-03-2018 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 SUPERFAMILY SSF63411 690 877 4.78E-24 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Gene3D G3DSA:3.30.830.10 463 680 2.8E-28 T 28-03-2018 WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Pfam PF00675 Insulinase (Peptidase family M16) 482 592 1.2E-6 T 28-03-2018 IPR011765 Peptidase M16, N-terminal WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 Pfam PF00675 Insulinase (Peptidase family M16) 35 155 6.9E-14 T 28-03-2018 IPR011765 Peptidase M16, N-terminal WM46_RS15425 16f81ad555c26179127f6c65b42457cc 911 SUPERFAMILY SSF63411 444 673 2.87E-32 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 TIGRFAM TIGR01276 thiB: thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein 6 327 1.5E-184 T 28-03-2018 IPR005967 Thiamin/thiamin pyrophosphate ABC transporter, substrate-binding protein, Proteobacteria GO:0015888|GO:0030288|GO:0030975 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 Pfam PF13343 Bacterial extracellular solute-binding protein 73 289 4.1E-17 T 28-03-2018 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 SUPERFAMILY SSF53850 22 323 2.06E-63 T 28-03-2018 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 Gene3D G3DSA:3.40.190.10 16 135 5.3E-4 T 28-03-2018 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 18 321 6.8E-152 T 28-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 Gene3D G3DSA:3.40.190.10 136 275 7.1E-32 T 28-03-2018 WM46_RS14490 c47dbd47ba5d0507a149df929820c88e 327 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 119 136 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 50 2.2E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 Gene3D G3DSA:3.40.50.2300 58 177 4.9E-27 T 28-03-2018 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 SUPERFAMILY SSF47413 2 61 1.23E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 Gene3D G3DSA:1.10.260.40 4 57 4.6E-19 T 28-03-2018 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 SMART SM00354 3 73 1.8E-29 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 63 318 2.5E-31 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 Gene3D G3DSA:3.40.50.2300 178 323 5.9E-31 T 28-03-2018 WM46_RS12200 b9f12b626372cb76c057ed95ac4ddb01 338 SUPERFAMILY SSF53822 63 337 8.78E-51 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 272 1.1E-30 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Gene3D G3DSA:3.30.420.10 321 542 1.4E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SUPERFAMILY SSF47807 171 291 3.74E-30 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SUPERFAMILY SSF88723 7 170 1.23E-56 T 28-03-2018 IPR029060 PIN domain-like WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 9 170 1.9E-54 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 ProSitePatterns PS00447 DNA polymerase family A signature. 754 773 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Pfam PF01612 3'-5' exonuclease 330 517 5.5E-45 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SUPERFAMILY SSF53098 326 518 7.12E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SMART SM00474 330 517 9.8E-49 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SMART SM00482 686 892 2.8E-127 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 845 861 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 813 824 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 700 723 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 655 677 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 791 802 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 754 779 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 678 693 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 730 743 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 PRINTS PR00868 DNA-polymerase family A (pol I) signature 875 888 1.3E-80 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SMART SM00475 7 268 1.2E-142 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Gene3D G3DSA:1.20.1060.10 543 656 1.4E-32 T 28-03-2018 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Pfam PF00476 DNA polymerase family A 552 925 5.8E-160 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SUPERFAMILY SSF56672 523 928 2.22E-162 T 28-03-2018 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Gene3D G3DSA:1.10.150.20 185 269 1.1E-24 T 28-03-2018 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 TIGRFAM TIGR00593 pola: DNA polymerase I 9 928 1.0E-288 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Gene3D G3DSA:3.30.70.370 657 750 5.4E-18 T 28-03-2018 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Gene3D G3DSA:3.30.70.370 754 928 3.2E-53 T 28-03-2018 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 SMART SM00279 173 208 1.2E-13 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 WM46_RS18880 30611d7e366a84db1a54f9a6dd36cd18 928 Gene3D G3DSA:3.40.50.1010 7 184 4.9E-68 T 28-03-2018 IPR029060 PIN domain-like WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 2.8E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 2.8E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 2.8E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 2.8E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 2.8E-56 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 SMART SM00283 265 512 3.1E-93 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 Pfam PF02203 Tar ligand binding domain homologue 4 165 3.0E-11 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 480 1.0E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 Gene3D G3DSA:1.10.287.950 47 321 1.0E-20 T 28-03-2018 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 Gene3D G3DSA:1.10.287.950 322 516 7.1E-47 T 28-03-2018 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 SUPERFAMILY SSF58104 232 517 6.67E-73 T 28-03-2018 WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 ProSitePatterns PS00538 Bacterial chemotaxis sensory transducers signature. 290 312 - T 28-03-2018 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site WM46_RS15955 712b1f2b089b73e3660dd31422a44145 546 SMART SM00304 212 264 1.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS17100 e7823b4b61e4c9a944276af76137f429 482 SUPERFAMILY SSF53720 7 480 2.49E-168 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS17100 e7823b4b61e4c9a944276af76137f429 482 Pfam PF00171 Aldehyde dehydrogenase family 25 476 2.2E-170 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS17100 e7823b4b61e4c9a944276af76137f429 482 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 29 475 5.7E-201 T 28-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 WM46_RS17100 e7823b4b61e4c9a944276af76137f429 482 Gene3D G3DSA:3.40.309.10 272 463 1.1E-70 T 28-03-2018 WM46_RS17100 e7823b4b61e4c9a944276af76137f429 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS17100 e7823b4b61e4c9a944276af76137f429 482 Gene3D G3DSA:3.40.605.10 7 271 2.6E-98 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS25815 4e5afd2b1a66f7802bf03ae49fb0298a 598 Pfam PF10592 AIPR protein 245 560 5.8E-77 T 28-03-2018 IPR018891 Abortive bacteriophage infection, resistance WM46_RS02050 f5d238dd8f45cb5c7bc7abb41a09600b 216 Gene3D G3DSA:3.40.1080.10 2 210 7.0E-65 T 28-03-2018 WM46_RS02050 f5d238dd8f45cb5c7bc7abb41a09600b 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 43 51 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS02050 f5d238dd8f45cb5c7bc7abb41a09600b 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 204 3.0E-93 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 WM46_RS02050 f5d238dd8f45cb5c7bc7abb41a09600b 216 SUPERFAMILY SSF100950 2 209 1.01E-67 T 28-03-2018 WM46_RS02050 f5d238dd8f45cb5c7bc7abb41a09600b 216 Pfam PF01144 Coenzyme A transferase 5 185 3.5E-38 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS02050 f5d238dd8f45cb5c7bc7abb41a09600b 216 SMART SM00882 5 198 2.9E-66 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS09610 ff3bd862adabbade722fb598246e10a4 220 Hamap MF_00789 UPF0319 protein YccT [yccT]. 3 216 25.315 T 28-03-2018 IPR018635 Uncharacterised protein family UPF0319 WM46_RS09610 ff3bd862adabbade722fb598246e10a4 220 Pfam PF09829 Uncharacterized protein conserved in bacteria (DUF2057) 22 213 1.7E-42 T 28-03-2018 IPR018635 Uncharacterised protein family UPF0319 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 SUPERFAMILY SSF54975 2 93 7.2E-31 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 PRINTS PR00112 Acylphosphatase signature 61 81 3.6E-8 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 PRINTS PR00112 Acylphosphatase signature 26 51 3.6E-8 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 PRINTS PR00112 Acylphosphatase signature 5 20 3.6E-8 T 28-03-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 Hamap MF_01450 Acylphosphatase [yccX]. 2 92 31.071 T 28-03-2018 IPR028627 Acylphosphatase, bacteria GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 Gene3D G3DSA:3.30.70.100 1 93 9.5E-32 T 28-03-2018 WM46_RS09590 6ea79f173f5d9241af8ade5216ddf015 93 Pfam PF00708 Acylphosphatase 8 91 3.5E-27 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Pfam PF13361 UvrD-like helicase C-terminal domain 271 613 8.9E-72 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 SUPERFAMILY SSF52540 2 636 6.93E-163 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Gene3D G3DSA:1.10.486.10 377 552 4.9E-38 T 28-03-2018 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 668 41.076 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Gene3D G3DSA:3.40.50.300 1 134 3.8E-24 T 28-03-2018 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Gene3D G3DSA:3.40.50.300 135 276 2.2E-28 T 28-03-2018 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 265 9.5E-73 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 Gene3D G3DSA:3.40.50.300 277 376 3.3E-21 T 28-03-2018 WM46_RS19285 fa8129203216e86692657b096ec6d9de 674 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 667 0.0 T 28-03-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 WM46_RS15930 ffc4acde7cb48e0a96ded7393a905d13 567 SUPERFAMILY SSF56762 1 552 4.97E-169 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS15930 ffc4acde7cb48e0a96ded7393a905d13 567 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 28-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 WM46_RS15930 ffc4acde7cb48e0a96ded7393a905d13 567 Pfam PF00374 Nickel-dependent hydrogenase 39 552 2.6E-208 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 WM46_RS15930 ffc4acde7cb48e0a96ded7393a905d13 567 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 543 552 - T 28-03-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 WM46_RS15930 ffc4acde7cb48e0a96ded7393a905d13 567 Gene3D G3DSA:1.10.645.10 1 552 1.2E-181 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS04925 c5c814c6858253349263f0047a19452e 581 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 214 7.8E-18 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM46_RS04925 c5c814c6858253349263f0047a19452e 581 Gene3D G3DSA:3.90.1310.10 29 228 7.7E-45 T 28-03-2018 WM46_RS04925 c5c814c6858253349263f0047a19452e 581 Gene3D G3DSA:3.40.710.10 229 577 9.6E-81 T 28-03-2018 WM46_RS04925 c5c814c6858253349263f0047a19452e 581 SUPERFAMILY SSF56519 56 227 1.96E-44 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 WM46_RS04925 c5c814c6858253349263f0047a19452e 581 Pfam PF00905 Penicillin binding protein transpeptidase domain 253 547 4.6E-79 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS04925 c5c814c6858253349263f0047a19452e 581 SUPERFAMILY SSF56601 228 556 3.32E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 12 298 2.9E-125 T 28-03-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 174 192 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 113 138 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 28 51 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 216 237 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 238 259 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 74 96 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 53 73 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 194 215 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 280 298 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 260 279 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 6 26 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 150 173 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 PRINTS PR01002 Flagellar protein FlgJ signature 298 315 4.8E-174 T 28-03-2018 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 SMART SM00047 145 309 7.8E-65 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 Pfam PF10135 Rod binding protein 50 97 2.8E-17 T 28-03-2018 IPR019301 Flagellar protein FlgJ, N-terminal WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 165 298 1.3E-19 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 WM46_RS08750 420e134d4d66d2981d487b7f214e9a4a 316 Gene3D G3DSA:1.10.530.10 148 302 1.5E-33 T 28-03-2018 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 240 320 1.1E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 Gene3D G3DSA:3.90.226.10 330 601 1.2E-57 T 28-03-2018 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 SMART SM00228 246 323 4.3E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 SUPERFAMILY SSF50156 219 344 3.01E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 195 551 5.3E-128 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 536 667 1.4E-38 T 28-03-2018 IPR020992 Tail specific protease, C-terminal WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 SUPERFAMILY SSF52096 194 264 2.49E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 SUPERFAMILY SSF52096 350 537 2.49E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 Pfam PF03572 Peptidase family S41 356 529 2.2E-52 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 Gene3D G3DSA:3.30.750.44 155 245 7.8E-21 T 28-03-2018 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 Gene3D G3DSA:2.30.42.10 246 329 4.1E-15 T 28-03-2018 WM46_RS04880 f0e62fbb8caef74dcaaa63dd66c7fe9d 682 SMART SM00245 326 531 5.5E-79 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 Pfam PF00155 Aminotransferase class I and II 126 388 1.3E-20 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 9.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 9.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 Gene3D G3DSA:3.40.640.10 114 353 1.1E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 Gene3D G3DSA:1.10.10.10 1 68 9.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 SUPERFAMILY SSF46785 1 69 8.55E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 SMART SM00345 7 66 1.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 SUPERFAMILY SSF53383 91 444 2.69E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS25665 5a2b4947e594a84bd52e38fb4b0fe149 447 Gene3D G3DSA:3.90.1150.10 354 447 2.2E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 SUPERFAMILY SSF47413 4 63 2.33E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 Gene3D G3DSA:1.10.260.40 1 67 1.4E-17 T 28-03-2018 WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 Pfam PF01381 Helix-turn-helix 8 60 3.7E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 Gene3D G3DSA:2.10.109.10 72 201 3.5E-19 T 28-03-2018 WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 Pfam PF00717 Peptidase S24-like 118 183 4.4E-11 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 SMART SM00530 6 60 3.6E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS13575 0ca9b45e4118ed425b411e3d9744e6c6 207 SUPERFAMILY SSF51306 75 198 3.27E-22 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS26075 970e5446d964ae0d303004614c009099 259 PIRSF PIRSF003073 1 256 1.7E-84 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein WM46_RS26075 970e5446d964ae0d303004614c009099 259 SUPERFAMILY SSF52540 71 243 6.52E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26075 970e5446d964ae0d303004614c009099 259 SMART SM00382 100 234 1.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS26075 970e5446d964ae0d303004614c009099 259 Pfam PF01695 IstB-like ATP binding protein 56 233 2.6E-62 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 WM46_RS26075 970e5446d964ae0d303004614c009099 259 Gene3D G3DSA:3.40.50.300 34 242 6.0E-16 T 28-03-2018 WM46_RS20045 75e8883ff84791000cc5043234833227 459 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 192 436 1.3E-38 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 WM46_RS20045 75e8883ff84791000cc5043234833227 459 Gene3D G3DSA:3.90.1820.10 1 456 4.7E-98 T 28-03-2018 WM46_RS20045 75e8883ff84791000cc5043234833227 459 Pfam PF02056 Family 4 glycosyl hydrolase 2 177 4.3E-30 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 PRINTS PR00732 Glycosyl hydrolase family 4 signature 188 200 2.4E-20 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.4E-20 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 PRINTS PR00732 Glycosyl hydrolase family 4 signature 162 173 2.4E-20 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 2.4E-20 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 PRINTS PR00732 Glycosyl hydrolase family 4 signature 136 153 2.4E-20 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 2.4E-20 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20045 75e8883ff84791000cc5043234833227 459 SUPERFAMILY SSF51735 2 167 1.9E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20045 75e8883ff84791000cc5043234833227 459 SUPERFAMILY SSF56327 166 451 2.73E-47 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 SUPERFAMILY SSF53178 3 192 1.2E-70 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 Gene3D G3DSA:3.40.50.1470 1 194 5.3E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 189 3.3E-72 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 Pfam PF01195 Peptidyl-tRNA hydrolase 5 188 1.9E-53 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 182 36.196 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 WM46_RS05475 f36674fd8f5c37f1cb48c34362574985 194 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 110 120 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 SMART SM00382 226 363 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 460 507 2.2E-28 T 28-03-2018 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 Gene3D G3DSA:1.10.8.60 372 442 2.3E-17 T 28-03-2018 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 SUPERFAMILY SSF55021 2 69 5.88E-5 T 28-03-2018 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 285 300 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 Gene3D G3DSA:3.30.450.20 82 186 4.6E-10 T 28-03-2018 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 Pfam PF00158 Sigma-54 interaction domain 206 365 1.3E-55 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 230 243 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 Gene3D G3DSA:3.30.70.260 1 81 2.0E-7 T 28-03-2018 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 SUPERFAMILY SSF55785 82 172 4.38E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 412 421 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 SUPERFAMILY SSF46689 454 507 4.93E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 Gene3D G3DSA:1.10.10.60 448 508 7.9E-8 T 28-03-2018 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 Gene3D G3DSA:3.40.50.300 201 371 2.6E-23 T 28-03-2018 WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 SUPERFAMILY SSF52540 206 440 2.37E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06110 e27e9b4bc2718153cc139b220ae8ee53 513 SMART SM00091 80 146 3.5E-7 T 28-03-2018 IPR000014 PAS domain WM46_RS19130 3c920cac8b9a9f7a4a3b56ae2d13ccb9 848 PIRSF PIRSF001444 1 848 0.0 T 28-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 WM46_RS19130 3c920cac8b9a9f7a4a3b56ae2d13ccb9 848 ProSitePatterns PS01092 Adenylate cyclase class-I signature 1. 242 253 - T 28-03-2018 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 WM46_RS19130 3c920cac8b9a9f7a4a3b56ae2d13ccb9 848 Pfam PF01295 Adenylate cyclase, class-I 228 825 1.5E-258 T 28-03-2018 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 WM46_RS19130 3c920cac8b9a9f7a4a3b56ae2d13ccb9 848 ProSitePatterns PS01093 Adenylate cyclase class-I signature 2. 598 612 - T 28-03-2018 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 WM46_RS19130 3c920cac8b9a9f7a4a3b56ae2d13ccb9 848 Pfam PF12633 Adenylate cyclase NT domain 5 200 2.0E-80 T 28-03-2018 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 Pfam PF02254 TrkA-N domain 403 513 1.6E-24 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 Gene3D G3DSA:1.20.91.10 228 309 4.1E-13 T 28-03-2018 WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 Hamap MF_01412 Glutathione-regulated potassium-efflux system protein KefB [kefB]. 2 598 47.385 T 28-03-2018 IPR020884 Glutathione-regulated potassium-efflux system protein KefB GO:0005886|GO:0006813|GO:0015503 WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 Gene3D G3DSA:3.40.50.720 397 562 1.1E-19 T 28-03-2018 WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 SUPERFAMILY SSF51735 402 529 3.57E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 Pfam PF00999 Sodium/hydrogen exchanger family 11 373 3.5E-69 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM46_RS17635 2c74c5f8ee0f3498d3ae87c5938b5df2 601 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 283 1.0E-93 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 SUPERFAMILY SSF53041 1 138 9.16E-43 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 Gene3D G3DSA:1.10.10.60 129 181 1.9E-10 T 28-03-2018 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 Gene3D G3DSA:1.20.5.40 108 128 5.4E-13 T 28-03-2018 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 ProSitePatterns PS00398 Site-specific recombinases signature 2. 58 70 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 SUPERFAMILY SSF46689 141 181 2.62E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 Pfam PF00239 Resolvase, N terminal domain 3 137 8.0E-41 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 SMART SM00857 3 139 6.3E-51 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 Gene3D G3DSA:3.40.50.1390 1 107 1.1E-36 T 28-03-2018 WM46_RS26100 b066c66c45801debda198fcc16f4d9cd 185 Pfam PF02796 Helix-turn-helix domain of resolvase 141 181 8.5E-11 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 WM46_RS03050 6339c2becda42efeab341de794050fce 274 SUPERFAMILY SSF51735 2 266 9.87E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS03050 6339c2becda42efeab341de794050fce 274 Gene3D G3DSA:3.40.50.720 2 269 9.2E-22 T 28-03-2018 WM46_RS03050 6339c2becda42efeab341de794050fce 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 213 4.9E-9 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.3E-32 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.6E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.6E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.6E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 SUPERFAMILY SSF47729 1 90 1.62E-31 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 Gene3D G3DSA:4.10.520.10 1 90 1.0E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS12615 c7f3973e254898425cc5b3b1c8cf5a11 90 SMART SM00411 1 90 3.8E-42 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS20270 c403165fa6c228d26b36ddde67cc0030 143 SUPERFAMILY SSF52821 15 142 3.8E-32 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS20270 c403165fa6c228d26b36ddde67cc0030 143 Gene3D G3DSA:3.40.250.10 21 143 1.2E-26 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS20270 c403165fa6c228d26b36ddde67cc0030 143 Pfam PF00581 Rhodanese-like domain 43 133 5.5E-18 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS20270 c403165fa6c228d26b36ddde67cc0030 143 SMART SM00450 40 138 1.3E-23 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 Pfam PF07690 Major Facilitator Superfamily 283 434 3.0E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 308 325 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 30 425 9.3E-151 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 SUPERFAMILY SSF103473 18 439 1.44E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 Gene3D G3DSA:1.20.1250.20 235 438 6.0E-20 T 28-03-2018 WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 Pfam PF00083 Sugar (and other) transporter 24 226 8.0E-24 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS20715 40f705355adc94b79eebeeeb911e753f 440 Gene3D G3DSA:1.20.1250.20 19 234 2.3E-23 T 28-03-2018 WM46_RS18215 855515863555463c2503f46d95a61327 221 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 12 205 4.2E-68 T 28-03-2018 IPR003744 Queuosine precursor transporter WM46_RS18215 855515863555463c2503f46d95a61327 221 Pfam PF02592 Putative vitamin uptake transporter 43 199 1.3E-35 T 28-03-2018 IPR003744 Queuosine precursor transporter WM46_RS24635 b412a931d8878b0e96fbe2c786c51765 191 Pfam PF03641 Possible lysine decarboxylase 46 175 4.7E-38 T 28-03-2018 IPR031100 LOG family WM46_RS24635 b412a931d8878b0e96fbe2c786c51765 191 SUPERFAMILY SSF102405 1 179 6.11E-60 T 28-03-2018 WM46_RS24635 b412a931d8878b0e96fbe2c786c51765 191 Gene3D G3DSA:3.40.50.450 2 191 3.2E-58 T 28-03-2018 WM46_RS24635 b412a931d8878b0e96fbe2c786c51765 191 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 6.0E-56 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 Pfam PF00294 pfkB family carbohydrate kinase 6 297 3.6E-75 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 PRINTS PR00990 Ribokinase signature 36 55 1.7E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 PRINTS PR00990 Ribokinase signature 220 231 1.7E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 PRINTS PR00990 Ribokinase signature 9 30 1.7E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 PRINTS PR00990 Ribokinase signature 108 121 1.7E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 PRINTS PR00990 Ribokinase signature 176 191 1.7E-37 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 8 302 1.4E-107 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 Gene3D G3DSA:3.40.1190.20 1 309 4.8E-85 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 SUPERFAMILY SSF53613 7 307 9.98E-85 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS19420 611046bad196295c4f51be855b1f3d99 309 Hamap MF_01987 Ribokinase [rbsK]. 5 304 25.925 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 WM46_RS06185 17e55562459b67437cfa05c6367e3175 218 Pfam PF01144 Coenzyme A transferase 7 201 5.0E-38 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS06185 17e55562459b67437cfa05c6367e3175 218 Gene3D G3DSA:3.40.1080.10 5 213 1.2E-53 T 28-03-2018 WM46_RS06185 17e55562459b67437cfa05c6367e3175 218 SMART SM00882 7 204 5.5E-65 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS06185 17e55562459b67437cfa05c6367e3175 218 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 5 210 8.7E-91 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 WM46_RS06185 17e55562459b67437cfa05c6367e3175 218 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 45 53 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS06185 17e55562459b67437cfa05c6367e3175 218 SUPERFAMILY SSF100950 6 211 1.47E-61 T 28-03-2018 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 216 229 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 386 408 8.6E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 69 86 8.6E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 157 166 8.6E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01181 Diaminopimelate decarboxylase signature 293 311 8.6E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 SUPERFAMILY SSF51419 25 276 1.57E-56 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 SUPERFAMILY SSF50621 250 419 1.49E-59 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 Gene3D G3DSA:3.20.20.10 34 262 1.3E-47 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 30 376 4.6E-25 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 Gene3D G3DSA:2.40.37.10 263 420 1.2E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 51 69 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 33 275 3.4E-64 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 419 1.0E-140 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 14 419 39.211 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 182 195 1.3E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 376 389 1.3E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 51 69 1.3E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 71 83 1.3E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS24795 97c1a2866d953c80b84846cc35abbdd9 420 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 265 284 1.3E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 141 172 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 SUPERFAMILY SSF51569 7 304 1.57E-79 T 28-03-2018 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 SMART SM01130 9 303 2.9E-94 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 Gene3D G3DSA:3.20.20.70 7 310 5.1E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 PIRSF PIRSF001365 6 310 5.4E-74 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 Pfam PF00701 Dihydrodipicolinate synthetase family 10 300 2.9E-70 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 1.4E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 111 127 1.4E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 1.4E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09410 2c48af645532b2aa2b27e95bd0baf9ff 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 43 64 1.4E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS16070 4d5116c6c9fd9b03cff2d524743db06c 193 SUPERFAMILY SSF52218 1 192 5.45E-41 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS16070 4d5116c6c9fd9b03cff2d524743db06c 193 Gene3D G3DSA:3.40.50.360 1 193 8.0E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS16070 4d5116c6c9fd9b03cff2d524743db06c 193 Pfam PF02525 Flavodoxin-like fold 3 190 1.3E-36 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS05070 7bfb99c1813fbd23581b93f20fe33d16 278 Gene3D G3DSA:3.60.15.10 2 268 1.7E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS05070 7bfb99c1813fbd23581b93f20fe33d16 278 SUPERFAMILY SSF56281 5 252 4.98E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS05070 7bfb99c1813fbd23581b93f20fe33d16 278 Pfam PF00753 Metallo-beta-lactamase superfamily 19 82 2.9E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS05070 7bfb99c1813fbd23581b93f20fe33d16 278 SMART SM00849 21 249 6.8E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 Gene3D G3DSA:1.20.58.100 423 542 3.2E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 3 582 0.0 T 28-03-2018 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 SUPERFAMILY SSF51905 361 416 7.86E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 SUPERFAMILY SSF51905 3 250 7.86E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 SUPERFAMILY SSF56425 227 358 9.12E-43 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 581 1.0E-38 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 Gene3D G3DSA:3.90.700.10 246 352 6.3E-30 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 SUPERFAMILY SSF46977 444 583 1.1E-45 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 Gene3D G3DSA:4.10.80.40 543 576 5.7E-14 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.4E-5 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 1.4E-5 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.9E-10 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 1.9E-10 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 PIRSF PIRSF000171 1 574 6.0E-42 T 28-03-2018 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 Pfam PF00890 FAD binding domain 7 397 2.1E-115 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 581 6.8E-248 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22810 8a874d7cabe596cabbb6e4fa2286a755 594 Gene3D G3DSA:3.50.50.60 1 245 2.4E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09490 995a48613b3dd7a5e671b9f8884e287b 267 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 1.7E-101 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS09490 995a48613b3dd7a5e671b9f8884e287b 267 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 36.851 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS09490 995a48613b3dd7a5e671b9f8884e287b 267 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS09490 995a48613b3dd7a5e671b9f8884e287b 267 SUPERFAMILY SSF51366 1 266 2.35E-88 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS09490 995a48613b3dd7a5e671b9f8884e287b 267 Gene3D G3DSA:3.20.20.70 2 267 9.1E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS09490 995a48613b3dd7a5e671b9f8884e287b 267 Pfam PF00290 Tryptophan synthase alpha chain 8 266 6.2E-95 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS20010 c46b4e42e315c6c25e3241ea2f4abc56 365 Gene3D G3DSA:3.20.20.70 1 365 1.2E-124 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS20010 c46b4e42e315c6c25e3241ea2f4abc56 365 SUPERFAMILY SSF51395 2 364 3.36E-122 T 28-03-2018 WM46_RS20010 c46b4e42e315c6c25e3241ea2f4abc56 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 344 2.5E-87 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 SMART SM00420 6 58 3.0E-20 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 Gene3D G3DSA:1.10.10.10 2 74 6.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 SUPERFAMILY SSF100950 77 234 2.09E-26 T 28-03-2018 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 SMART SM01134 73 233 1.2E-64 T 28-03-2018 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 Pfam PF00455 DeoR C terminal sensor domain 76 231 6.0E-48 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.3E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.3E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 Gene3D G3DSA:3.40.50.1360 75 239 7.5E-34 T 28-03-2018 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 3.2E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS14205 e5d4e763e5d174e6729dee86195ca081 255 SUPERFAMILY SSF46785 5 73 5.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 Gene3D G3DSA:3.40.50.1970 9 184 1.5E-42 T 28-03-2018 WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 TIGRFAM TIGR02638 lactal_redase: lactaldehyde reductase 3 379 9.8E-184 T 28-03-2018 IPR013460 Lactaldehyde reductase KEGG: 00630+1.1.1.77|KEGG: 00640+1.1.1.77 WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 259 279 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 Gene3D G3DSA:1.20.1090.10 186 389 1.2E-61 T 28-03-2018 WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 375 1.9E-115 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS09405 1528e9d18aad274590857ec1852bda4c 389 SUPERFAMILY SSF56796 10 386 4.32E-120 T 28-03-2018 WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 SUPERFAMILY SSF54975 1 133 2.06E-35 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 Pfam PF00563 EAL domain 169 389 1.9E-44 T 28-03-2018 IPR001633 EAL domain WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 Pfam PF04940 Sensors of blue-light using FAD 2 92 1.4E-23 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 SUPERFAMILY SSF141868 167 389 7.19E-47 T 28-03-2018 IPR001633 EAL domain WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 SMART SM00052 151 394 2.3E-28 T 28-03-2018 IPR001633 EAL domain WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 Gene3D G3DSA:3.20.20.450 152 392 4.2E-44 T 28-03-2018 IPR001633 EAL domain WM46_RS05295 81aaa2437a4b1f56b80c09b4a047a2e3 406 SMART SM01034 2 94 3.9E-35 T 28-03-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 WM46_RS19205 a33b881fc1a49697f63b8c5c66dd4c8e 359 Pfam PF07429 4-alpha-L-fucosyltransferase glycosyl transferase group 56 1 355 3.4E-180 T 28-03-2018 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 WM46_RS19205 a33b881fc1a49697f63b8c5c66dd4c8e 359 Hamap MF_01002 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase [wecF]. 1 359 64.789 T 28-03-2018 IPR009993 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase GO:0008417|GO:0009246|GO:0036065 WM46_RS19205 a33b881fc1a49697f63b8c5c66dd4c8e 359 Gene3D G3DSA:3.40.50.2000 171 350 1.7E-5 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Pfam PF00384 Molybdopterin oxidoreductase 92 564 1.6E-82 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 49 824 0.0 T 28-03-2018 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 SUPERFAMILY SSF50692 675 824 5.65E-39 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 506 523 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 SUPERFAMILY SSF53706 51 665 5.37E-160 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Gene3D G3DSA:3.40.228.10 182 438 1.1E-50 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Gene3D G3DSA:3.90.55.10 43 129 1.9E-15 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Gene3D G3DSA:3.90.55.10 530 605 1.7E-19 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Gene3D G3DSA:2.40.40.20 662 818 6.1E-28 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Gene3D G3DSA:3.40.228.10 606 661 1.3E-8 T 28-03-2018 WM46_RS02345 abeb7a50e14c0845a0f9c9d04ca2d8c7 832 Pfam PF01568 Molydopterin dinucleotide binding domain 680 800 2.8E-19 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 515 1.3E-11 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 396 1.3E-11 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 618 634 1.3E-11 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 331 7.7E-100 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 SUPERFAMILY SSF51905 468 627 4.47E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 Gene3D G3DSA:3.40.50.720 370 478 4.8E-18 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 SUPERFAMILY SSF51971 333 518 3.77E-39 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 SUPERFAMILY SSF51395 1 362 9.87E-108 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 Gene3D G3DSA:3.20.20.70 2 369 5.2E-110 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 Gene3D G3DSA:3.50.50.60 479 625 6.1E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 619 633 4.7E-6 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 376 398 4.7E-6 T 28-03-2018 WM46_RS16355 1120e3b2f5650cc299543bd920615f53 672 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 376 644 6.4E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS03695 d2cb41f516e47cdaa185dbb18dd5fc68 266 Gene3D G3DSA:3.40.390.10 77 245 1.3E-23 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 WM46_RS03695 d2cb41f516e47cdaa185dbb18dd5fc68 266 Pfam PF06167 Glucose-regulated metallo-peptidase M90 15 243 1.3E-64 T 28-03-2018 IPR010384 MtfA family WM46_RS03695 d2cb41f516e47cdaa185dbb18dd5fc68 266 Hamap MF_01593 Protein MtfA [mtfA]. 1 265 63.434 T 28-03-2018 IPR010384 MtfA family WM46_RS03695 d2cb41f516e47cdaa185dbb18dd5fc68 266 SUPERFAMILY SSF55486 34 245 6.81E-42 T 28-03-2018 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.1E-41 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 PIRSF PIRSF000149 1 331 3.9E-137 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 5.1E-48 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 5.1E-48 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 5.1E-48 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 5.1E-48 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 5.1E-48 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 1.2E-72 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 SUPERFAMILY SSF55347 149 312 1.73E-83 T 28-03-2018 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 Gene3D G3DSA:3.40.50.720 1 159 4.9E-79 T 28-03-2018 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 3.6E-135 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 SMART SM00846 3 150 2.2E-96 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 SUPERFAMILY SSF51735 3 166 1.39E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08340 91dda9119e3c63454d5fb2712ad7fe20 331 Gene3D G3DSA:3.30.360.10 160 314 4.1E-84 T 28-03-2018 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 SUPERFAMILY SSF143243 9 194 2.09E-46 T 28-03-2018 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 468 537 7.4E-11 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 296 464 4.8E-34 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 Gene3D G3DSA:1.10.645.10 379 535 2.8E-30 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 Gene3D G3DSA:1.10.645.10 175 378 1.3E-44 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 Pfam PF00374 Nickel-dependent hydrogenase 218 286 6.4E-13 T 28-03-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 151 7.0E-25 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 SUPERFAMILY SSF56762 193 537 3.66E-109 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 216 227 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25405 30168de8000a2c3f07dfadbc4c36b46a 569 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 36 152 1.2E-25 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS13370 3217f90431d2d6ca334cfc83bfe10224 458 Pfam PF07690 Major Facilitator Superfamily 40 413 1.2E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS13370 3217f90431d2d6ca334cfc83bfe10224 458 TIGRFAM TIGR02332 HpaX: 4-hydroxyphenylacetate permease 28 439 8.9E-257 T 28-03-2018 IPR012707 4-hydroxyphenylacetate permease GO:1900754|GO:1901241 WM46_RS13370 3217f90431d2d6ca334cfc83bfe10224 458 SUPERFAMILY SSF103473 22 449 7.72E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS13370 3217f90431d2d6ca334cfc83bfe10224 458 Gene3D G3DSA:1.20.1250.20 14 243 7.9E-32 T 28-03-2018 WM46_RS13370 3217f90431d2d6ca334cfc83bfe10224 458 Gene3D G3DSA:1.20.1250.20 247 455 1.4E-24 T 28-03-2018 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Pfam PF12836 Helix-hairpin-helix motif 491 555 1.6E-28 T 28-03-2018 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Gene3D G3DSA:1.10.150.310 499 630 2.4E-43 T 28-03-2018 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Gene3D G3DSA:1.10.10.650 3 102 6.3E-33 T 28-03-2018 IPR023319 Tex-like protein, HTH domain WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SUPERFAMILY SSF158832 2 322 1.7E-120 T 28-03-2018 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SUPERFAMILY SSF47781 470 558 5.0E-28 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SUPERFAMILY SSF47781 560 632 3.33E-19 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Pfam PF09371 Tex-like protein N-terminal domain 10 193 8.4E-69 T 28-03-2018 IPR018974 Tex-like protein, N-terminal WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Pfam PF00575 S1 RNA binding domain 649 720 9.5E-24 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Gene3D G3DSA:1.10.3500.10 361 498 2.8E-39 T 28-03-2018 IPR023323 Tex-like domain WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Gene3D G3DSA:1.10.3500.10 103 360 1.8E-77 T 28-03-2018 IPR023323 Tex-like domain WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SMART SM00732 327 424 2.5E-35 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SUPERFAMILY SSF50249 638 723 5.36E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Gene3D G3DSA:2.40.50.140 643 725 9.5E-26 T 28-03-2018 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SUPERFAMILY SSF53098 323 469 9.1E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 Pfam PF16921 Tex protein YqgF-like domain 328 451 3.9E-50 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain WM46_RS17865 75fcda4e63216e21358251277dad21b2 771 SMART SM00316 649 720 2.5E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 Pfam PF01926 50S ribosome-binding GTPase 200 318 5.5E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 SUPERFAMILY SSF54980 365 420 1.22E-13 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 PIRSF PIRSF006809 3 421 1.3E-151 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 6.1E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 6.1E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 6.1E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 361 9.8E-155 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 1.0E-30 T 28-03-2018 IPR025121 GTPase HflX, N-terminal WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 Gene3D G3DSA:3.40.50.300 157 401 1.8E-27 T 28-03-2018 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 Hamap MF_00900 GTPase HflX [hflX]. 27 390 47.028 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 SUPERFAMILY SSF52540 197 373 7.39E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22890 fceb3c1acfa9d2d6538b08d767048b64 426 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 1.2E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 396 223.737 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 SUPERFAMILY SSF51658 1 133 9.56E-77 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 SUPERFAMILY SSF51658 163 383 9.56E-77 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 388 2.5E-154 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 Gene3D G3DSA:3.20.20.150 1 393 1.2E-105 T 28-03-2018 WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 392 4.3E-208 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 WM46_RS02330 e2b6eccb36d1bc36d8dcce109d4a2a87 396 PIRSF PIRSF016049 1 394 1.4E-180 T 28-03-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 SUPERFAMILY SSF46548 6 82 8.89E-17 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 56 67 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 Gene3D G3DSA:3.30.70.20 63 387 2.4E-4 T 28-03-2018 WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 Pfam PF02754 Cysteine-rich domain 293 376 1.4E-14 T 28-03-2018 IPR004017 Cysteine-rich domain WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 Pfam PF02754 Cysteine-rich domain 163 249 2.7E-15 T 28-03-2018 IPR004017 Cysteine-rich domain WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 Gene3D G3DSA:3.30.70.20 4 62 8.7E-9 T 28-03-2018 WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 TIGRFAM TIGR03379 glycerol3P_GlpC: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit 3 395 2.1E-228 T 28-03-2018 IPR017753 Glycerol-3-phosphate dehydrogenase, GlpC subunit GO:0006810|GO:0016020 WM46_RS01960 6f62d67da38885a167096c8a0a011fee 396 Pfam PF13183 4Fe-4S dicluster domain 6 70 5.4E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS19720 4a5cb1c71980fe9c1a22948696635af1 142 Pfam PF00011 Hsp20/alpha crystallin family 39 135 2.9E-20 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain WM46_RS19720 4a5cb1c71980fe9c1a22948696635af1 142 Gene3D G3DSA:2.60.40.790 5 135 1.9E-20 T 28-03-2018 IPR008978 HSP20-like chaperone WM46_RS19720 4a5cb1c71980fe9c1a22948696635af1 142 SUPERFAMILY SSF49764 29 134 1.08E-19 T 28-03-2018 IPR008978 HSP20-like chaperone WM46_RS19720 4a5cb1c71980fe9c1a22948696635af1 142 Hamap MF_02001 Small heat shock protein IbpB [ibpB]. 1 142 45.364 T 28-03-2018 IPR022848 Small heat shock protein IbpB WM46_RS07280 55d0718b888887c8ec9e543232d67e89 117 Pfam PF12680 SnoaL-like domain 9 97 1.1E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain WM46_RS07280 55d0718b888887c8ec9e543232d67e89 117 Gene3D G3DSA:3.10.450.50 1 114 2.9E-20 T 28-03-2018 WM46_RS07280 55d0718b888887c8ec9e543232d67e89 117 SUPERFAMILY SSF54427 1 115 3.95E-26 T 28-03-2018 IPR032710 NTF2-like domain WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 52.406 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 PIRSF PIRSF000450 1 308 4.1E-145 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 Pfam PF04204 Homoserine O-succinyltransferase 2 299 6.2E-130 T 28-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 5.0E-143 T 28-03-2018 WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 SUPERFAMILY SSF52317 17 297 3.5E-99 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 Gene3D G3DSA:3.40.50.880 34 301 2.1E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS21335 d9d3db5ee0a010a35d2043f6ca40afb2 309 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 302 1.7E-163 T 28-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 WM46_RS13110 4c004bc4f64598086fdf140bd75bad05 343 PIRSF PIRSF002825 1 340 3.1E-71 T 28-03-2018 IPR026045 Ferric binding protein WM46_RS13110 4c004bc4f64598086fdf140bd75bad05 343 Gene3D G3DSA:3.40.190.10 145 295 9.1E-36 T 28-03-2018 WM46_RS13110 4c004bc4f64598086fdf140bd75bad05 343 Gene3D G3DSA:3.40.190.10 25 144 2.7E-11 T 28-03-2018 WM46_RS13110 4c004bc4f64598086fdf140bd75bad05 343 Pfam PF13343 Bacterial extracellular solute-binding protein 75 288 7.8E-33 T 28-03-2018 WM46_RS13110 4c004bc4f64598086fdf140bd75bad05 343 SUPERFAMILY SSF53850 25 328 2.12E-70 T 28-03-2018 WM46_RS13730 75d2f9522080e4cb46b3e12b1d6cc725 256 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 137 157 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site WM46_RS13730 75d2f9522080e4cb46b3e12b1d6cc725 256 Pfam PF00795 Carbon-nitrogen hydrolase 6 241 4.3E-31 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS13730 75d2f9522080e4cb46b3e12b1d6cc725 256 SUPERFAMILY SSF56317 4 249 6.41E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS13730 75d2f9522080e4cb46b3e12b1d6cc725 256 Gene3D G3DSA:3.60.110.10 2 254 5.8E-56 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS07900 a09e85d54349972d2a1317a486b48dc1 414 Pfam PF07690 Major Facilitator Superfamily 19 356 1.3E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07900 a09e85d54349972d2a1317a486b48dc1 414 SUPERFAMILY SSF103473 7 392 2.49E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07900 a09e85d54349972d2a1317a486b48dc1 414 Gene3D G3DSA:1.20.1250.20 5 199 3.3E-22 T 28-03-2018 WM46_RS07900 a09e85d54349972d2a1317a486b48dc1 414 Gene3D G3DSA:1.20.1250.20 200 391 1.3E-13 T 28-03-2018 WM46_RS06065 c889a18f00352edcdd4cdece62c439b1 547 Gene3D G3DSA:3.40.190.10 209 304 2.5E-23 T 28-03-2018 WM46_RS06065 c889a18f00352edcdd4cdece62c439b1 547 SUPERFAMILY SSF53850 36 537 1.81E-133 T 28-03-2018 WM46_RS06065 c889a18f00352edcdd4cdece62c439b1 547 PIRSF PIRSF002741 1 543 1.1E-93 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS06065 c889a18f00352edcdd4cdece62c439b1 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 458 2.2E-82 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS06065 c889a18f00352edcdd4cdece62c439b1 547 Gene3D G3DSA:3.90.76.10 45 208 1.2E-34 T 28-03-2018 WM46_RS06065 c889a18f00352edcdd4cdece62c439b1 547 Gene3D G3DSA:3.10.105.10 305 510 1.9E-53 T 28-03-2018 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 59 4.2E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 SUPERFAMILY SSF47413 12 70 3.0E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 Gene3D G3DSA:3.40.50.2300 65 184 9.0E-27 T 28-03-2018 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 SMART SM00354 12 82 2.4E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 15 33 - T 28-03-2018 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 Gene3D G3DSA:1.10.260.40 13 64 1.2E-19 T 28-03-2018 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 Gene3D G3DSA:3.40.50.2300 185 319 5.8E-29 T 28-03-2018 WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 SUPERFAMILY SSF53822 71 339 1.26E-52 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS01680 2388eb2021222f201f5021c535c1b045 339 Pfam PF13377 Periplasmic binding protein-like domain 180 339 1.3E-29 T 28-03-2018 WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 Gene3D G3DSA:1.10.10.10 126 228 2.6E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 SMART SM00448 3 116 4.0E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 SMART SM00862 150 225 2.8E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 Gene3D G3DSA:3.40.50.2300 2 125 1.8E-36 T 28-03-2018 WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 SUPERFAMILY SSF52172 3 184 8.9E-43 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.5E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 5.3E-116 T 28-03-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 WM46_RS12915 587e9ee3ee492c16ca4c7af1b04ebf61 229 Pfam PF00072 Response regulator receiver domain 5 117 7.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Gene3D G3DSA:3.90.870.10 192 382 1.1E-49 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 ProSitePatterns PS00150 Acylphosphatase signature 1. 13 23 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 PIRSF PIRSF006256 4 746 1.0E-270 T 28-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 SUPERFAMILY SSF55821 175 379 5.19E-47 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Pfam PF01300 Telomere recombination 208 373 1.1E-48 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 11 738 3.0E-296 T 28-03-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Pfam PF07503 HypF finger 158 190 1.2E-15 T 28-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Pfam PF07503 HypF finger 108 141 4.8E-16 T 28-03-2018 IPR011125 Zinc finger, HypF-type GO:0008270 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Gene3D G3DSA:3.30.70.100 2 97 2.0E-21 T 28-03-2018 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Pfam PF00708 Acylphosphatase 9 90 9.0E-17 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 SUPERFAMILY SSF54975 9 91 2.4E-21 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 WM46_RS25455 56827666752c7d2f7be0b0631eb9364b 746 Gene3D G3DSA:3.30.420.40 566 717 7.3E-29 T 28-03-2018 WM46_RS17630 11523538c3d555dc27bee831754292fd 66 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 3 60 7.8E-32 T 28-03-2018 IPR012658 Conserved hypothetical protein CHP02443 WM46_RS17630 11523538c3d555dc27bee831754292fd 66 Gene3D G3DSA:2.20.25.10 10 51 1.5E-4 T 28-03-2018 WM46_RS17630 11523538c3d555dc27bee831754292fd 66 Pfam PF09526 Probable metal-binding protein (DUF2387) 4 57 2.7E-18 T 28-03-2018 IPR012658 Conserved hypothetical protein CHP02443 WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 SUPERFAMILY SSF46785 21 92 1.71E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 Pfam PF07729 FCD domain 118 241 2.6E-16 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 1.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 1.8E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 Gene3D G3DSA:1.10.10.10 20 90 2.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 SMART SM00895 117 242 4.4E-8 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 87 4.3E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 SUPERFAMILY SSF48008 114 241 5.23E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 SMART SM00345 29 88 2.4E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23535 f8195f1fbbc6499cc9561589e68771be 245 Gene3D G3DSA:1.20.120.530 102 242 1.1E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 Gene3D G3DSA:3.65.10.10 21 228 1.6E-64 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 PIRSF PIRSF000505 1 427 4.1E-154 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 426 35.654 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 423 4.8E-142 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 Gene3D G3DSA:3.65.10.10 229 425 4.5E-69 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 1.3E-154 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM46_RS09865 3a7bcda88570d851694fae85f16a236f 427 SUPERFAMILY SSF55205 1 423 1.13E-145 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 Gene3D G3DSA:3.40.50.2300 58 167 3.4E-22 T 28-03-2018 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 Pfam PF13377 Periplasmic binding protein-like domain 169 329 1.8E-32 T 28-03-2018 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.4E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.4E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 Gene3D G3DSA:3.40.50.2300 168 332 2.3E-44 T 28-03-2018 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 SMART SM00354 1 71 1.2E-33 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 Gene3D G3DSA:1.10.260.40 2 57 1.9E-24 T 28-03-2018 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 SUPERFAMILY SSF47413 1 58 1.49E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 7.8E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS02455 79e295f80e75cb35547364ae11fa8b6c 341 SUPERFAMILY SSF53822 60 330 9.23E-77 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS22985 78865c3244993fff51ecd036064e0988 131 SUPERFAMILY SSF54995 1 103 4.58E-37 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22985 78865c3244993fff51ecd036064e0988 131 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS22985 78865c3244993fff51ecd036064e0988 131 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 3.1E-38 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22985 78865c3244993fff51ecd036064e0988 131 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.693 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS22985 78865c3244993fff51ecd036064e0988 131 Pfam PF01250 Ribosomal protein S6 3 91 2.7E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22985 78865c3244993fff51ecd036064e0988 131 Gene3D G3DSA:3.30.70.60 1 100 2.6E-30 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 WM46_RS13855 c7c5c30bacc6bb8f3d222c55c6d62232 232 Pfam PF17185 NlpE C-terminal OB domain 142 230 2.0E-33 T 28-03-2018 IPR033450 NlpE, C-terminal OB domain WM46_RS13855 c7c5c30bacc6bb8f3d222c55c6d62232 232 Pfam PF04170 NlpE N-terminal domain 44 128 5.9E-26 T 28-03-2018 IPR007298 Copper resistance lipoprotein NlpE WM46_RS08240 69783557cd97ce213ca9f663c185fb72 137 Gene3D G3DSA:3.90.79.10 1 134 2.7E-29 T 28-03-2018 WM46_RS08240 69783557cd97ce213ca9f663c185fb72 137 Pfam PF00293 NUDIX domain 6 123 2.1E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS08240 69783557cd97ce213ca9f663c185fb72 137 PRINTS PR00502 NUDIX hydrolase family signature 32 46 5.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS08240 69783557cd97ce213ca9f663c185fb72 137 PRINTS PR00502 NUDIX hydrolase family signature 46 61 5.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS08240 69783557cd97ce213ca9f663c185fb72 137 SUPERFAMILY SSF55811 1 125 2.44E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS08240 69783557cd97ce213ca9f663c185fb72 137 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 PIRSF PIRSF004750 6 282 2.7E-129 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 SUPERFAMILY SSF55620 186 267 1.93E-10 T 28-03-2018 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 282 167.432 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 21 131 4.2E-48 T 28-03-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 Pfam PF14489 QueF-like protein 196 270 2.6E-27 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 Gene3D G3DSA:3.30.1130.10 21 136 2.1E-39 T 28-03-2018 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 TIGRFAM TIGR03138 QueF: queuine synthase 11 282 2.3E-128 T 28-03-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 WM46_RS25055 2e53f1bc32fbddd9144169c7ea37d54a 282 Gene3D G3DSA:3.30.1130.10 144 282 2.2E-48 T 28-03-2018 WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 175 382 5.0E-17 T 28-03-2018 WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 SUPERFAMILY SSF102114 3 346 3.27E-41 T 28-03-2018 WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 Pfam PF04055 Radical SAM superfamily 13 184 3.7E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 277 363 3.6E-19 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 6 382 7.8E-152 T 28-03-2018 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 Gene3D G3DSA:3.20.20.70 1 337 7.9E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS08285 897ac4ab693f457072336f9ad3c9d20e 412 Pfam PF13186 Iron-sulfur cluster-binding domain 279 337 6.0E-8 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 Gene3D G3DSA:3.40.50.300 122 283 2.1E-24 T 28-03-2018 WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 SUPERFAMILY SSF52540 122 348 1.87E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 Gene3D G3DSA:1.10.40.50 285 353 4.7E-22 T 28-03-2018 WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 Gene3D G3DSA:2.40.50.140 43 110 1.5E-19 T 28-03-2018 WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 Pfam PF03193 RsgA GTPase 108 284 1.1E-56 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 81 342 1.6E-99 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 WM46_RS22830 0357a5118e73a2497550612d3f24cab5 358 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 48 348 37.809 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 PIRSF PIRSF000538 3 465 1.2E-82 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 438 4.3E-23 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 249 1.4E-80 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 SUPERFAMILY SSF53067 256 463 5.99E-40 T 28-03-2018 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 Gene3D G3DSA:3.30.420.40 1 245 9.9E-60 T 28-03-2018 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 Gene3D G3DSA:3.30.420.40 246 465 1.9E-37 T 28-03-2018 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 SUPERFAMILY SSF53067 6 252 1.8E-60 T 28-03-2018 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 351 371 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 TIGRFAM TIGR02628 fuculo_kin_coli: L-fuculokinase 4 463 3.5E-227 T 28-03-2018 IPR013450 L-fuculokinase GO:0005975|GO:0008737 KEGG: 00051+2.7.1.51 WM46_RS25000 3a439e7c36adcd40f006f2f595fb340c 465 Hamap MF_00986 L-fuculokinase [fucK]. 3 464 61.784 T 28-03-2018 IPR013450 L-fuculokinase GO:0005975|GO:0008737 KEGG: 00051+2.7.1.51 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 Gene3D G3DSA:3.40.190.10 181 267 3.5E-18 T 28-03-2018 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 Gene3D G3DSA:1.10.10.10 1 92 1.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 Pfam PF03466 LysR substrate binding domain 90 293 1.4E-40 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 SUPERFAMILY SSF53850 88 294 5.01E-41 T 28-03-2018 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 Gene3D G3DSA:3.40.190.10 93 180 1.4E-19 T 28-03-2018 WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 SUPERFAMILY SSF46785 11 112 2.79E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03685 648090f14e4f0299702ff87962a1756c 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 2.0E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03515 499bf3b1b812a2725b273664386d119a 554 ProDom PD025428 SUBUNIT GLYCEROL DEHYDRATASE LARGE LYASE DHAB ALPHA DIOL B12-DEPENDENT METABOLISM 8 549 0.0 T 28-03-2018 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 WM46_RS03515 499bf3b1b812a2725b273664386d119a 554 Pfam PF02286 Dehydratase large subunit 1 551 0.0 T 28-03-2018 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 WM46_RS03515 499bf3b1b812a2725b273664386d119a 554 PIRSF PIRSF018507 1 554 0.0 T 28-03-2018 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 WM46_RS03515 499bf3b1b812a2725b273664386d119a 554 Gene3D G3DSA:3.20.20.350 2 553 0.0 T 28-03-2018 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 WM46_RS03515 499bf3b1b812a2725b273664386d119a 554 SUPERFAMILY SSF51703 1 553 4.71E-292 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 SUPERFAMILY SSF50621 482 584 3.84E-7 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 SUPERFAMILY SSF51419 92 369 2.43E-67 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 Gene3D G3DSA:3.20.20.10 115 369 2.2E-33 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 Gene3D G3DSA:2.40.37.10 22 114 1.4E-13 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 Gene3D G3DSA:2.40.37.10 423 604 1.1E-62 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 263 276 7.6E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 566 579 7.6E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 124 142 7.6E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 146 158 7.6E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 357 376 7.6E-19 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 196 217 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 488 509 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 347 364 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 170 185 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 220 242 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 116 130 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 566 587 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 513 538 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PRINTS PR01180 Arginine decarboxylase signature 92 107 2.0E-74 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 124 142 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 100 367 1.2E-72 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 TIGRFAM TIGR01273 speA: arginine decarboxylase 31 656 3.4E-279 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 301 314 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 28 657 43.538 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS15015 059dc53cf16b250d6574b5ff1cce3658 658 PIRSF PIRSF001336 17 658 9.3E-257 T 28-03-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 WM46_RS06865 e348ce3acf5ec2725864ce1378736db1 288 SUPERFAMILY SSF46689 6 76 2.69E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06865 e348ce3acf5ec2725864ce1378736db1 288 SUPERFAMILY SSF53697 103 266 1.59E-5 T 28-03-2018 WM46_RS06865 e348ce3acf5ec2725864ce1378736db1 288 Gene3D G3DSA:1.10.10.10 1 77 2.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06865 e348ce3acf5ec2725864ce1378736db1 288 Gene3D G3DSA:3.40.50.10490 103 287 2.8E-5 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1045 0.0 T 28-03-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82866 805 1042 9.81E-44 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82693 138 184 8.11E-21 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82693 271 328 8.11E-21 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Gene3D G3DSA:3.30.2090.10 723 809 5.8E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82693 46 126 1.46E-20 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82714 186 269 1.26E-20 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Pfam PF00873 AcrB/AcrD/AcrF family 6 1037 7.3E-237 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Gene3D G3DSA:3.30.70.1430 45 139 1.9E-21 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Gene3D G3DSA:1.20.1640.10 823 1048 4.9E-31 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Gene3D G3DSA:1.20.1640.10 287 517 1.7E-44 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82866 294 506 5.49E-41 T 28-03-2018 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 9.7E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 9.7E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 9.7E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 9.7E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 9.7E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 9.7E-23 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 SUPERFAMILY SSF82714 723 807 4.32E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Gene3D G3DSA:3.30.2090.10 183 271 1.5E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS11840 e0933a21f6be54d8956c8cc609adec37 1048 Gene3D G3DSA:3.30.70.1430 567 665 2.9E-8 T 28-03-2018 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 Gene3D G3DSA:3.40.50.2300 55 178 6.6E-23 T 28-03-2018 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 SUPERFAMILY SSF47413 1 58 1.33E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.1E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 SUPERFAMILY SSF53822 61 336 3.93E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 Gene3D G3DSA:3.40.50.2300 179 317 2.3E-40 T 28-03-2018 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 Gene3D G3DSA:1.10.260.40 2 54 4.7E-22 T 28-03-2018 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 Pfam PF13377 Periplasmic binding protein-like domain 171 331 2.6E-31 T 28-03-2018 WM46_RS15375 a016a58f2669c20e36798c61313226b0 341 SMART SM00354 1 71 4.6E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.7E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 SUPERFAMILY SSF53822 60 340 4.91E-93 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 SUPERFAMILY SSF47413 1 59 1.29E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 Gene3D G3DSA:1.10.260.40 2 54 9.4E-20 T 28-03-2018 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 Gene3D G3DSA:3.40.50.2300 55 176 1.2E-30 T 28-03-2018 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 Pfam PF13377 Periplasmic binding protein-like domain 171 331 1.8E-39 T 28-03-2018 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 SMART SM00354 1 71 3.0E-37 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 Gene3D G3DSA:3.40.50.2300 177 335 1.1E-46 T 28-03-2018 WM46_RS07625 09c7ca5d82977534ac0dbb70d201d690 341 Hamap MF_01277 HTH-type transcriptional repressor PurR [purR]. 1 335 58.887 T 28-03-2018 IPR023588 Transcription regulator HTH, PurR GO:0006355 WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 711 728 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 Gene3D G3DSA:2.170.130.10 18 150 9.5E-25 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 Gene3D G3DSA:2.40.170.20 152 728 4.3E-54 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 SUPERFAMILY SSF56935 19 728 1.1E-95 T 28-03-2018 WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 42 728 2.4E-144 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 Pfam PF00593 TonB dependent receptor 236 724 6.0E-28 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS08585 a2f35a6ecfcf15327ad814d813ffa009 728 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 142 3.7E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS04620 afba04b835c144cb99ec956df2d5ba29 118 Gene3D G3DSA:3.30.1330.70 1 118 1.4E-7 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 WM46_RS04620 afba04b835c144cb99ec956df2d5ba29 118 SUPERFAMILY SSF103084 1 115 2.62E-8 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 WM46_RS04620 afba04b835c144cb99ec956df2d5ba29 118 Pfam PF05866 Endodeoxyribonuclease RusA 48 115 1.1E-11 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 Gene3D G3DSA:3.40.640.10 185 304 3.6E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 Gene3D G3DSA:3.90.1150.10 305 421 4.9E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 Gene3D G3DSA:3.90.1150.10 22 184 8.9E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 Pfam PF00202 Aminotransferase class-III 22 418 4.6E-129 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 SUPERFAMILY SSF53383 24 419 2.74E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 419 1.5E-192 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 PIRSF PIRSF000521 9 130 2.0E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS18155 d2ccf755dd7e969d8e9aed1b6a2bda25 421 PIRSF PIRSF000521 125 421 1.2E-41 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 Pfam PF03466 LysR substrate binding domain 105 276 2.0E-17 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 Gene3D G3DSA:1.10.10.10 2 92 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 SUPERFAMILY SSF53850 108 277 4.89E-20 T 28-03-2018 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 Gene3D G3DSA:3.40.190.10 93 178 7.5E-5 T 28-03-2018 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 Gene3D G3DSA:3.40.190.10 179 268 3.7E-9 T 28-03-2018 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14900 0c5628d053a9ac85dec57e7d628c15cb 308 SUPERFAMILY SSF46785 3 87 4.54E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15080 6ebc1f0e0183ef9e96135b4116e215e0 234 PIRSF PIRSF004848 1 234 1.5E-71 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein WM46_RS15080 6ebc1f0e0183ef9e96135b4116e215e0 234 Gene3D G3DSA:3.20.20.10 1 234 9.8E-68 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS15080 6ebc1f0e0183ef9e96135b4116e215e0 234 SUPERFAMILY SSF51419 1 227 8.51E-79 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS15080 6ebc1f0e0183ef9e96135b4116e215e0 234 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 229 7.7E-97 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein WM46_RS15080 6ebc1f0e0183ef9e96135b4116e215e0 234 Pfam PF01168 Alanine racemase, N-terminal domain 5 229 3.8E-29 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS15080 6ebc1f0e0183ef9e96135b4116e215e0 234 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 79 93 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 Pfam PF03466 LysR substrate binding domain 89 292 4.8E-45 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 SUPERFAMILY SSF46785 4 84 6.39E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 Gene3D G3DSA:3.40.190.10 89 175 5.5E-14 T 28-03-2018 WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 SUPERFAMILY SSF53850 90 297 2.79E-48 T 28-03-2018 WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 Gene3D G3DSA:1.10.10.10 3 81 6.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20730 97d837d824930d3e91fbd2a5de8ee2fa 299 Gene3D G3DSA:3.40.190.10 176 265 1.7E-23 T 28-03-2018 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 Gene3D G3DSA:3.30.870.10 248 419 3.1E-19 T 28-03-2018 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 Gene3D G3DSA:3.30.870.10 14 238 2.9E-17 T 28-03-2018 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 SUPERFAMILY SSF56024 252 397 7.53E-19 T 28-03-2018 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 Pfam PF13091 PLD-like domain 257 404 1.4E-22 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 Pfam PF13091 PLD-like domain 40 153 2.3E-6 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 PIRSF PIRSF000850 1 451 8.7E-267 T 28-03-2018 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 SMART SM00155 352 379 1.8E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 SMART SM00155 133 159 0.012 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS00315 627df9afabc84e7a75a1e5f0605b3950 451 SUPERFAMILY SSF56024 9 215 6.06E-27 T 28-03-2018 WM46_RS04065 b60984a56d9170b7f7fec41ef39639ec 185 SUPERFAMILY SSF52317 1 184 8.25E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS04065 b60984a56d9170b7f7fec41ef39639ec 185 Pfam PF01965 DJ-1/PfpI family 2 164 4.7E-31 T 28-03-2018 IPR002818 DJ-1/PfpI WM46_RS04065 b60984a56d9170b7f7fec41ef39639ec 185 Gene3D G3DSA:3.40.50.880 1 185 7.6E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 Gene3D G3DSA:3.30.70.270 309 465 2.2E-8 T 28-03-2018 WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 Gene3D G3DSA:3.20.20.450 476 729 1.1E-68 T 28-03-2018 IPR001633 EAL domain WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 SMART SM00052 487 729 2.6E-87 T 28-03-2018 IPR001633 EAL domain WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 SMART SM00267 315 473 1.2E-15 T 28-03-2018 IPR000160 GGDEF domain WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 SUPERFAMILY SSF141868 493 728 2.22E-67 T 28-03-2018 IPR001633 EAL domain WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 Pfam PF05231 MASE1 17 314 2.3E-50 T 28-03-2018 IPR007895 MASE1 WM46_RS01260 29515293de658d6dff7f90a6599d66b3 729 Pfam PF00563 EAL domain 493 724 2.6E-58 T 28-03-2018 IPR001633 EAL domain WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 Pfam PF00005 ABC transporter 24 181 7.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 Gene3D G3DSA:3.40.50.300 1 324 3.3E-75 T 28-03-2018 WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 317 4.5E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 297 5.4E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 SUPERFAMILY SSF52540 31 309 4.72E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20615 8db7fa0aa11f5b61e82a5dcb62469443 327 SMART SM00382 32 231 4.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 SUPERFAMILY SSF81340 6 426 1.1E-82 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 Hamap MF_01203 Voltage-gated ClC-type chloride channel ClcB [clcB]. 16 425 37.945 T 28-03-2018 IPR023790 Chloride channel, voltage-gated, ClcB GO:0006821|GO:0010447 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 PRINTS PR00762 Chloride channel signature 382 401 4.2E-21 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 PRINTS PR00762 Chloride channel signature 329 349 4.2E-21 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 PRINTS PR00762 Chloride channel signature 165 184 4.2E-21 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 PRINTS PR00762 Chloride channel signature 115 134 4.2E-21 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 PRINTS PR00762 Chloride channel signature 364 380 4.2E-21 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 Pfam PF00654 Voltage gated chloride channel 72 414 1.4E-68 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS07255 36d8a44558cd09ebb6b3cdaafaffd5dc 429 Gene3D G3DSA:1.10.3080.10 4 428 8.8E-70 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 Gene3D G3DSA:3.50.50.60 129 242 1.7E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 8.9E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 314 1.2E-124 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 Gene3D G3DSA:3.50.50.60 2 128 1.4E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 Gene3D G3DSA:3.50.50.60 251 321 1.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 SUPERFAMILY SSF51905 2 315 2.89E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.6E-41 T 28-03-2018 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.6E-41 T 28-03-2018 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.6E-41 T 28-03-2018 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 5.6E-41 T 28-03-2018 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 5.6E-41 T 28-03-2018 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 1.3E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09955 f19f6d08f6d9958003a994b3f247c5e4 322 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 Gene3D G3DSA:1.10.1270.10 8 108 4.7E-29 T 28-03-2018 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 Hamap MF_00475 Trp operon repressor [trpR]. 15 108 23.918 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 Pfam PF01371 Trp repressor protein 17 102 3.5E-28 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 PIRSF PIRSF003196 8 108 7.1E-40 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 ProDom PD012582 REPRESSOR TRANSCRIPTION TRP OPERON DNA-BINDING REGULATION HOMOLOG AROH FOR TRYPTOPHAN 10 101 5.0E-38 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 TIGRFAM TIGR01321 TrpR: trp operon repressor 11 103 7.0E-40 T 28-03-2018 IPR013335 Trp repressor, bacterial GO:0006355 WM46_RS14870 4fd63e05678e6c2450b0100ad2907d94 108 SUPERFAMILY SSF48295 5 105 2.14E-29 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 SUPERFAMILY SSF49354 37 156 1.47E-40 T 28-03-2018 IPR008962 PapD-like WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 180 233 2.0E-10 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 111 128 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 Gene3D G3DSA:2.60.40.10 158 241 5.5E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 37 156 7.0E-39 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 Gene3D G3DSA:2.60.40.10 37 157 9.7E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 SUPERFAMILY SSF49584 151 235 6.54E-20 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 PRINTS PR00969 Pili chaperone signature 173 188 4.8E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 PRINTS PR00969 Pili chaperone signature 83 104 4.8E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 PRINTS PR00969 Pili chaperone signature 138 153 4.8E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 PRINTS PR00969 Pili chaperone signature 38 47 4.8E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24610 a117e013dc46ed3ee625c4d87cd0d4cb 241 PRINTS PR00969 Pili chaperone signature 112 129 4.8E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 716 743 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 SUPERFAMILY SSF50692 618 648 5.8E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 SUPERFAMILY SSF50692 675 804 5.8E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 Pfam PF00384 Molybdopterin oxidoreductase 2 377 1.6E-22 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 Pfam PF01568 Molydopterin dinucleotide binding domain 682 797 3.4E-18 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 SUPERFAMILY SSF53706 1 639 8.34E-231 T 28-03-2018 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 Gene3D G3DSA:2.40.40.20 629 804 1.4E-40 T 28-03-2018 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 Gene3D G3DSA:3.40.228.10 1 270 1.6E-69 T 28-03-2018 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 803 0.0 T 28-03-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 Gene3D G3DSA:3.40.228.10 549 628 9.0E-14 T 28-03-2018 WM46_RS18685 47c642e93f374aceeefb74394ae50f6d 804 Gene3D G3DSA:3.40.50.740 271 449 4.1E-26 T 28-03-2018 WM46_RS02975 f863c48a030de0cb47c7b4b767a0814f 208 Gene3D G3DSA:3.40.50.1000 1 199 3.6E-8 T 28-03-2018 IPR023214 HAD-like domain WM46_RS02975 f863c48a030de0cb47c7b4b767a0814f 208 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 177 5.0E-12 T 28-03-2018 WM46_RS02975 f863c48a030de0cb47c7b4b767a0814f 208 SUPERFAMILY SSF56784 1 194 6.27E-15 T 28-03-2018 IPR023214 HAD-like domain WM46_RS02975 f863c48a030de0cb47c7b4b767a0814f 208 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 161 1.7E-15 T 28-03-2018 WM46_RS14540 4e9597747bdc2a45db155ee6ccc2fbb4 219 SUPERFAMILY SSF55120 8 216 3.36E-62 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS14540 4e9597747bdc2a45db155ee6ccc2fbb4 219 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 218 5.7E-59 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS14540 4e9597747bdc2a45db155ee6ccc2fbb4 219 Pfam PF00849 RNA pseudouridylate synthase 22 169 1.1E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS14540 4e9597747bdc2a45db155ee6ccc2fbb4 219 Gene3D G3DSA:3.30.2350.10 15 218 1.5E-58 T 28-03-2018 WM46_RS14540 4e9597747bdc2a45db155ee6ccc2fbb4 219 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 60 74 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 442 234.039 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 442 4.6E-197 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 PIRSF PIRSF000423 1 442 2.3E-209 T 28-03-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 Pfam PF00696 Amino acid kinase family 26 268 2.0E-32 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 Pfam PF00583 Acetyltransferase (GNAT) family 336 413 7.6E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 Gene3D G3DSA:3.40.1160.10 7 294 4.2E-54 T 28-03-2018 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 SUPERFAMILY SSF53633 5 291 1.17E-69 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 Gene3D G3DSA:3.40.630.30 297 442 9.1E-20 T 28-03-2018 WM46_RS24920 d20256c418b0f8df3ddfae0f8625d2cd 443 SUPERFAMILY SSF55729 297 418 4.87E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 SUPERFAMILY SSF46689 284 332 5.58E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 SUPERFAMILY SSF53822 10 298 5.5E-45 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 Pfam PF12833 Helix-turn-helix domain 309 384 3.1E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 SMART SM00342 301 384 9.1E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 Gene3D G3DSA:3.40.50.2300 2 107 7.9E-9 T 28-03-2018 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 338 380 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 SUPERFAMILY SSF46689 338 385 1.16E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 Gene3D G3DSA:3.40.50.2300 108 280 2.3E-30 T 28-03-2018 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 Gene3D G3DSA:1.10.10.60 281 339 3.3E-8 T 28-03-2018 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 353 368 7.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 368 384 7.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 Pfam PF13377 Periplasmic binding protein-like domain 113 277 2.0E-37 T 28-03-2018 WM46_RS20435 fe1cdfe9a33df874058c08f4be82607f 392 Gene3D G3DSA:1.10.10.60 340 387 4.9E-12 T 28-03-2018 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 32.2 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.0E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 PRINTS PR01249 Ribosomal protein L31 signature 46 64 5.0E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 PRINTS PR01249 Ribosomal protein L31 signature 31 46 5.0E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 Pfam PF01197 Ribosomal protein L31 1 65 1.2E-30 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 SUPERFAMILY SSF143800 1 66 5.89E-28 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS18380 f849475ff0ffdd35192584d632333477 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 1.5E-35 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS07715 024db9b4b20abcfd09bffe62e8f0ac0d 272 SUPERFAMILY SSF52540 24 258 5.06E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07715 024db9b4b20abcfd09bffe62e8f0ac0d 272 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS07715 024db9b4b20abcfd09bffe62e8f0ac0d 272 Pfam PF00005 ABC transporter 39 188 2.0E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07715 024db9b4b20abcfd09bffe62e8f0ac0d 272 Gene3D G3DSA:3.40.50.300 20 270 5.5E-79 T 28-03-2018 WM46_RS07715 024db9b4b20abcfd09bffe62e8f0ac0d 272 SMART SM00382 48 236 2.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07715 024db9b4b20abcfd09bffe62e8f0ac0d 272 PIRSF PIRSF039085 20 264 3.3E-102 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 SUPERFAMILY SSF52172 2 120 8.4E-29 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 SMART SM00448 2 112 2.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 Pfam PF00072 Response regulator receiver domain 4 112 5.2E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 Gene3D G3DSA:1.10.10.10 129 240 1.6E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 SUPERFAMILY SSF46894 135 234 7.09E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 Gene3D G3DSA:3.40.50.2300 1 128 6.5E-25 T 28-03-2018 WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 233 8.4E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS07360 f8cd00983ac430ba4f821ae9a3cf8aa0 248 SMART SM00862 157 233 2.4E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS19705 a99ff1d5922f9b318ee08f43dd83f15a 408 Gene3D G3DSA:2.140.10.30 2 394 1.5E-18 T 28-03-2018 WM46_RS19705 a99ff1d5922f9b318ee08f43dd83f15a 408 Pfam PF12566 Protein of unknown function (DUF3748) 63 179 6.7E-55 T 28-03-2018 IPR022223 Protein of unknown function DUF3748 WM46_RS19705 a99ff1d5922f9b318ee08f43dd83f15a 408 SUPERFAMILY SSF69304 18 147 2.35E-17 T 28-03-2018 WM46_RS19705 a99ff1d5922f9b318ee08f43dd83f15a 408 SUPERFAMILY SSF69304 307 404 2.35E-17 T 28-03-2018 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 1.5E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 1.5E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 1.5E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.5E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 1.5E-47 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.9E-42 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 7.3E-94 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 40.42 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 Pfam PF00303 Thymidylate synthase 2 264 5.0E-128 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 SUPERFAMILY SSF55831 1 264 3.27E-131 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS24875 5990b0377e0a92408eac81d986668eb6 264 Gene3D G3DSA:3.30.572.10 1 264 3.7E-134 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 WM46_RS03560 4502b706d487c736e206545bfd1cf428 379 PIRSF PIRSF026782 13 374 6.6E-133 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 WM46_RS03560 4502b706d487c736e206545bfd1cf428 379 SUPERFAMILY SSF111342 6 291 5.23E-86 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 WM46_RS03560 4502b706d487c736e206545bfd1cf428 379 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 17 367 31.049 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 WM46_RS03560 4502b706d487c736e206545bfd1cf428 379 Gene3D G3DSA:3.30.2110.10 19 188 8.4E-56 T 28-03-2018 WM46_RS03560 4502b706d487c736e206545bfd1cf428 379 Pfam PF01888 CbiD 17 273 6.1E-93 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 WM46_RS03560 4502b706d487c736e206545bfd1cf428 379 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 24 368 1.1E-85 T 28-03-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 SUPERFAMILY SSF81273 91 133 1.45E-11 T 28-03-2018 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 PIRSF PIRSF002096 1 133 7.7E-54 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 Gene3D G3DSA:4.10.430.10 92 133 1.6E-17 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 Pfam PF00816 H-NS histone family 32 127 3.8E-20 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 SUPERFAMILY SSF81273 2 58 4.71E-16 T 28-03-2018 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 SMART SM00528 86 133 6.2E-22 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25830 a7288f3cba7c78b94b95fbdc039e70c7 133 Gene3D G3DSA:1.10.287.1050 1 57 2.5E-21 T 28-03-2018 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 253 1.3E-100 T 28-03-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0006810|GO:0030288 WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 254 7.3E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 Gene3D G3DSA:3.40.190.10 141 258 1.3E-15 T 28-03-2018 WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 Gene3D G3DSA:3.40.190.10 16 140 6.4E-35 T 28-03-2018 WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 SMART SM00062 27 256 5.5E-76 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS01615 74e10dff76f43ccac28b55ca5cbe418b 260 SUPERFAMILY SSF53850 26 257 4.07E-65 T 28-03-2018 WM46_RS25015 debf64efc1d3f8f2276e68eef6830915 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 317 4.3E-49 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS25015 debf64efc1d3f8f2276e68eef6830915 327 Gene3D G3DSA:1.10.3470.10 38 325 1.7E-36 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 PIRSF PIRSF002888 2 331 2.1E-100 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 SUPERFAMILY SSF103039 49 231 4.18E-18 T 28-03-2018 IPR028976 CheC-like domain WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 Gene3D G3DSA:3.40.1550.10 46 234 5.9E-37 T 28-03-2018 IPR028976 CheC-like domain WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 89 105 2.9E-32 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 114 133 2.9E-32 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 2.9E-32 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 2.9E-32 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 321 3.8E-118 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 SUPERFAMILY SSF101801 249 323 1.19E-12 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 Pfam PF02154 Flagellar motor switch protein FliM 38 231 8.7E-80 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 Gene3D G3DSA:2.30.330.10 239 329 1.5E-15 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) WM46_RS03800 d5e645c08571cc9ac338e349c5e61913 334 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 321 5.4E-16 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 Gene3D G3DSA:3.30.565.10 314 465 3.7E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 1.9E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 Pfam PF08521 Two-component sensor kinase N-terminal 21 169 4.1E-38 T 28-03-2018 IPR013727 Two-component sensor kinase, N-terminal WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 SUPERFAMILY SSF47384 229 308 2.35E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 Gene3D G3DSA:1.10.287.130 236 306 1.7E-6 T 28-03-2018 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 SMART SM00388 246 311 7.1E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 SMART SM00387 358 469 1.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 SMART SM00304 193 245 1.5E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 Gene3D G3DSA:1.20.5.1040 7 61 2.9E-7 T 28-03-2018 WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 358 452 2.3E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25770 3f0e73d5bd284aca2d5edd39338ddb4e 475 SUPERFAMILY SSF55874 320 464 1.15E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 135 4.5E-7 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 SMART SM00382 49 332 2.7E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 SUPERFAMILY SSF52540 3 441 2.59E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Gene3D G3DSA:1.10.8.10 123 200 7.5E-30 T 28-03-2018 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Gene3D G3DSA:1.10.8.10 201 243 2.0E-18 T 28-03-2018 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 SMART SM01086 335 434 1.5E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Pfam PF07724 AAA domain (Cdc48 subfamily) 188 329 3.7E-43 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Gene3D G3DSA:3.40.50.300 7 122 1.1E-5 T 28-03-2018 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 335 405 9.2E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Gene3D G3DSA:1.10.8.60 335 431 2.8E-29 T 28-03-2018 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 443 43.72 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 WM46_RS18405 ffe7da47ebffaf339a298fff942e3574 443 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 443 1.3E-236 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 SUPERFAMILY SSF109604 3 190 2.04E-75 T 28-03-2018 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Pfam PF02824 TGS domain 388 447 2.3E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Pfam PF13291 ACT domain 623 700 7.1E-15 T 28-03-2018 IPR002912 ACT domain WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 SUPERFAMILY SSF81271 375 447 3.71E-21 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 SUPERFAMILY SSF81301 180 392 2.13E-62 T 28-03-2018 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Gene3D G3DSA:3.10.20.30 382 457 6.4E-24 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 SMART SM00471 41 153 1.2E-11 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 SUPERFAMILY SSF55021 628 700 3.85E-5 T 28-03-2018 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Gene3D G3DSA:3.30.460.10 188 325 7.2E-40 T 28-03-2018 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Pfam PF13328 HD domain 26 175 3.0E-53 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 SMART SM00954 235 345 1.1E-62 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Gene3D G3DSA:3.30.70.260 624 702 9.5E-9 T 28-03-2018 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 1.9E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 WM46_RS20080 7a00df23b144b54e4b1d9769f771796b 703 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 700 1.2E-292 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 WM46_RS17410 ae58e88d7ca05f62490a685f73cbb986 122 Pfam PF09350 Domain of unknown function (DUF1992) 7 73 5.6E-23 T 28-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain WM46_RS03770 332b1086922303b776c00304feda3745 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 191 2.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 152 179 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 4.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 4.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 4.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 SUPERFAMILY SSF46894 130 186 7.82E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 Gene3D G3DSA:1.10.10.10 61 199 2.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03770 332b1086922303b776c00304feda3745 207 SMART SM00421 135 192 2.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03770 332b1086922303b776c00304feda3745 207 Hamap MF_00982 Transcriptional regulatory protein RcsA [rcsA]. 1 207 49.473 T 28-03-2018 IPR030866 Transcriptional regulatory protein RcsA GO:0006355 WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 Gene3D G3DSA:3.30.70.1400 27 240 3.3E-24 T 28-03-2018 WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 Pfam PF01571 Aminomethyltransferase folate-binding domain 31 135 5.8E-9 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 SUPERFAMILY SSF101790 244 325 4.38E-26 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 SUPERFAMILY SSF103025 7 242 2.04E-66 T 28-03-2018 WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 187 251 1.8E-25 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 Hamap MF_01175 tRNA-modifying protein YgfZ [ygfZ]. 1 321 48.581 T 28-03-2018 IPR023758 tRNA-modifying protein YgfZ GO:0005542|GO:0009451 WM46_RS24240 d91de419cdb0c19c1e08c1a7ce2d8c3c 326 PIRSF PIRSF006487 9 294 2.4E-10 T 28-03-2018 WM46_RS18445 77786a1f15fe73d2642e4c4a5b2d4d24 248 SUPERFAMILY SSF52343 103 248 1.7E-38 T 28-03-2018 WM46_RS18445 77786a1f15fe73d2642e4c4a5b2d4d24 248 Gene3D G3DSA:2.40.30.10 1 95 2.4E-18 T 28-03-2018 WM46_RS18445 77786a1f15fe73d2642e4c4a5b2d4d24 248 Pfam PF00970 Oxidoreductase FAD-binding domain 18 90 2.9E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 WM46_RS18445 77786a1f15fe73d2642e4c4a5b2d4d24 248 Gene3D G3DSA:3.40.50.80 97 248 1.0E-25 T 28-03-2018 WM46_RS18445 77786a1f15fe73d2642e4c4a5b2d4d24 248 SUPERFAMILY SSF63380 3 100 9.32E-26 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS18445 77786a1f15fe73d2642e4c4a5b2d4d24 248 Pfam PF00175 Oxidoreductase NAD-binding domain 111 222 8.6E-19 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM46_RS17710 34ac6f49391f274bfe5da8de1713f4a8 55 Pfam PF10832 Protein of unknown function (DUF2559) 2 55 1.7E-29 T 28-03-2018 IPR022541 Protein of unknown function DUF2559 WM46_RS17710 34ac6f49391f274bfe5da8de1713f4a8 55 ProDom PD026929 YHFG 1 36 3.0E-10 T 28-03-2018 IPR022541 Protein of unknown function DUF2559 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 9.8E-62 T 28-03-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 SUPERFAMILY SSF54292 4 109 3.85E-35 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 92 2.0E-15 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 PRINTS PR00355 Adrenodoxin signature 42 52 6.0E-11 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 PRINTS PR00355 Adrenodoxin signature 60 74 6.0E-11 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 PRINTS PR00355 Adrenodoxin signature 83 91 6.0E-11 T 28-03-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 Gene3D G3DSA:3.10.20.30 8 111 1.9E-34 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS00645 b5bc4c23351f3f3c8ccfa16126838bb4 111 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 28-03-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 Pfam PF00027 Cyclic nucleotide-binding domain 48 127 2.4E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 SUPERFAMILY SSF46785 161 231 6.05E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 SMART SM00100 25 143 3.2E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 Gene3D G3DSA:2.60.120.10 1 144 2.0E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 Gene3D G3DSA:1.10.10.10 145 233 1.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 Pfam PF13545 Crp-like helix-turn-helix domain 163 229 1.4E-8 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS19300 f266b1beea62ebe55615022c037004bd 233 SUPERFAMILY SSF51206 43 152 1.83E-23 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like WM46_RS13075 8b3f242a1f5ae71ce86f113e292ff521 255 SUPERFAMILY SSF52540 1 213 4.18E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13075 8b3f242a1f5ae71ce86f113e292ff521 255 Pfam PF00005 ABC transporter 17 156 3.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS13075 8b3f242a1f5ae71ce86f113e292ff521 255 Gene3D G3DSA:3.40.50.300 1 220 7.0E-60 T 28-03-2018 WM46_RS13075 8b3f242a1f5ae71ce86f113e292ff521 255 SMART SM00382 26 205 4.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS13075 8b3f242a1f5ae71ce86f113e292ff521 255 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 Pfam PF00654 Voltage gated chloride channel 67 391 5.9E-19 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 Gene3D G3DSA:1.10.3080.10 4 399 7.9E-32 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 Hamap MF_01115 Putative ion-transport protein YfeO [yfeO]. 9 410 38.124 T 28-03-2018 IPR022969 Chloride channel YfeO WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 PRINTS PR00762 Chloride channel signature 320 340 2.9E-7 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 PRINTS PR00762 Chloride channel signature 153 172 2.9E-7 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 PRINTS PR00762 Chloride channel signature 103 122 2.9E-7 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 WM46_RS01310 1dbdb87f37afcb9fbd2351e0e56f2469 411 SUPERFAMILY SSF81340 9 398 4.71E-41 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 SMART SM00420 4 56 2.3E-25 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 Pfam PF00455 DeoR C terminal sensor domain 69 225 1.4E-46 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 SUPERFAMILY SSF46785 1 59 5.91E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 Gene3D G3DSA:3.40.50.1360 59 230 8.6E-34 T 28-03-2018 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 54 7.1E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 22 36 7.1E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 Gene3D G3DSA:1.10.10.10 1 56 8.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 SMART SM01134 67 227 5.3E-60 T 28-03-2018 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 SUPERFAMILY SSF100950 67 227 2.83E-29 T 28-03-2018 WM46_RS05955 79fedc23ca104ab21e1140d4ec353471 249 Pfam PF08220 DeoR-like helix-turn-helix domain 4 59 1.4E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Gene3D G3DSA:3.40.50.720 230 420 3.4E-50 T 28-03-2018 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 SMART SM00984 324 420 1.9E-21 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 SUPERFAMILY SSF48179 206 299 4.42E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 188 1.8E-58 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 PIRSF PIRSF000124 4 419 3.6E-76 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 293 1.5E-26 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Gene3D G3DSA:3.40.50.720 4 205 2.4E-46 T 28-03-2018 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Gene3D G3DSA:1.20.5.170 206 229 1.0E-14 T 28-03-2018 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 SUPERFAMILY SSF52413 311 419 1.22E-24 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 419 9.8E-18 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 416 5.5E-120 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 PIRSF PIRSF500136 1 420 1.1E-147 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 SUPERFAMILY SSF51735 5 198 1.21E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS19235 b16a161b25848075c4c84c44d67bcfe8 420 Hamap MF_02029 UDP-N-acetyl-D-mannosamine dehydrogenase [wecC]. 1 420 81.831 T 28-03-2018 IPR032891 UDP-N-acetyl-D-mannosamine dehydrogenase WecC GO:0009246|GO:0089714 KEGG: 00520+1.1.1.336|MetaCyc: PWY-7335 WM46_RS13570 0e91a9ffcb07ca83341aa33222338c65 70 Pfam PF01381 Helix-turn-helix 7 60 1.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS13570 0e91a9ffcb07ca83341aa33222338c65 70 SUPERFAMILY SSF47413 1 66 1.29E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS13570 0e91a9ffcb07ca83341aa33222338c65 70 SMART SM00530 6 60 8.3E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS13570 0e91a9ffcb07ca83341aa33222338c65 70 Gene3D G3DSA:1.10.260.40 1 70 2.9E-19 T 28-03-2018 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 Pfam PF01435 Peptidase family M48 78 258 2.8E-24 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 Pfam PF14559 Tetratricopeptide repeat 354 418 1.7E-9 T 28-03-2018 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 Gene3D G3DSA:1.25.20.10 130 372 6.2E-7 T 28-03-2018 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 Gene3D G3DSA:1.25.20.10 373 484 1.3E-8 T 28-03-2018 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 4 484 41.809 T 28-03-2018 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 Gene3D G3DSA:3.30.2010.10 64 129 5.6E-15 T 28-03-2018 WM46_RS00825 fb718a0fad4b87b7e0fc7df0114c635f 487 SUPERFAMILY SSF48452 310 426 2.28E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 Pfam PF01012 Electron transfer flavoprotein domain 27 168 8.4E-15 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 Gene3D G3DSA:3.40.50.1220 186 313 6.2E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 SUPERFAMILY SSF52402 6 177 1.95E-21 T 28-03-2018 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 Gene3D G3DSA:3.40.50.620 2 181 4.1E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 SMART SM00893 7 177 8.2E-11 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 PIRSF PIRSF000089 3 313 9.3E-83 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 SUPERFAMILY SSF52467 190 310 1.04E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 255 281 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 273 4.7E-29 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 WM46_RS14620 4f5860af3dd1be5fa79395cafc3e197f 313 Hamap MF_01056 Protein FixB [fixB]. 1 313 58.009 T 28-03-2018 IPR023461 Electron transfer flavoprotein FixB subunit GO:0009437 WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 Gene3D G3DSA:1.10.275.10 2 197 7.5E-72 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 503 2.0E-219 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 Pfam PF00221 Aromatic amino acid lyase 11 471 3.5E-184 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 Gene3D G3DSA:1.20.200.10 199 505 1.9E-116 T 28-03-2018 WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 SUPERFAMILY SSF48557 3 504 4.24E-190 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS10605 61fc955732d7a1a86e463440894de1a5 506 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 504 44.487 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 28-03-2018 WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 SUPERFAMILY SSF56784 1 269 1.88E-76 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 Gene3D G3DSA:3.40.50.1000 1 270 1.1E-47 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 1.3E-76 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 8.4E-69 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19670 a0ea8013161f9d6a234747adfdbc9c06 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 2.4E-32 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 SUPERFAMILY SSF52922 185 317 8.9E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 SUPERFAMILY SSF52518 10 177 1.66E-35 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 SMART SM00861 13 178 2.4E-23 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 Pfam PF02779 Transketolase, pyrimidine binding domain 12 171 1.2E-20 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 Pfam PF02780 Transketolase, C-terminal domain 189 309 1.2E-31 T 28-03-2018 IPR033248 Transketolase, C-terminal domain WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 Gene3D G3DSA:3.40.50.920 175 317 8.3E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS01705 1168a2dbcaf2dc6b290c25d513f931df 317 Gene3D G3DSA:3.40.50.970 1 174 9.9E-34 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Gene3D G3DSA:3.40.50.300 1154 1436 8.7E-6 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Pfam PF16330 MukB hinge domain 645 810 3.0E-74 T 28-03-2018 IPR032520 MukB, hinge domain WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Gene3D G3DSA:1.10.287.510 500 602 4.4E-5 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Hamap MF_01800 Chromosome partition protein MukB [mukB]. 1 1471 11.306 T 28-03-2018 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 PIRSF PIRSF005246 1 1486 0.0 T 28-03-2018 IPR012090 Chromosome partition protein MukB GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Gene3D G3DSA:1.10.287.620 982 1119 2.7E-9 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1336 1424 7.3E-15 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Pfam PF04310 MukB N-terminal 2 227 3.3E-124 T 28-03-2018 IPR007406 MukB, N-terminal domain GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 SUPERFAMILY SSF52540 1268 1433 1.89E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 SUPERFAMILY SSF52540 21 55 1.89E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Gene3D G3DSA:1.20.120.330 329 484 0.0034 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Gene3D G3DSA:3.40.1140.10 1 227 8.4E-10 T 28-03-2018 WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 SUPERFAMILY SSF52540 22 224 6.95E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09785 a7fbeca16d9290a8dc8a862049419e13 1486 Gene3D G3DSA:1.20.5.170 624 822 0.06 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Gene3D G3DSA:1.10.1060.10 2 144 3.7E-40 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 PRINTS PR00419 Adrenodoxin reductase family signature 324 337 3.0E-38 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 PRINTS PR00419 Adrenodoxin reductase family signature 148 170 3.0E-38 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 PRINTS PR00419 Adrenodoxin reductase family signature 171 184 3.0E-38 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 PRINTS PR00419 Adrenodoxin reductase family signature 290 304 3.0E-38 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 PRINTS PR00419 Adrenodoxin reductase family signature 213 223 3.0E-38 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 SUPERFAMILY SSF51971 145 401 1.12E-68 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Gene3D G3DSA:3.40.50.20 145 242 2.9E-17 T 28-03-2018 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 6 472 2.1E-267 T 28-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 147 459 1.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 25 134 9.2E-38 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Gene3D G3DSA:3.50.50.60 403 472 4.8E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 SUPERFAMILY SSF46548 7 157 6.8E-41 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Gene3D G3DSA:3.50.50.60 315 401 5.6E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS16990 ebef6c46401aa0eaffde9fbbd54a9e0c 472 Gene3D G3DSA:3.50.50.60 243 314 3.0E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01820 644eaf3b561f4b787c05ffed713aef71 485 Pfam PF00361 Proton-conducting membrane transporter 122 420 4.7E-90 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01820 644eaf3b561f4b787c05ffed713aef71 485 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 475 17.865 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 WM46_RS01820 644eaf3b561f4b787c05ffed713aef71 485 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 475 1.9E-147 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 SMART SM00895 106 227 4.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 1.4E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 SUPERFAMILY SSF48008 105 225 8.89E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 Gene3D G3DSA:1.10.10.10 2 79 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 Gene3D G3DSA:1.20.120.530 94 231 1.8E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 SUPERFAMILY SSF46785 10 81 1.79E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 Pfam PF07729 FCD domain 108 225 7.5E-20 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.5E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS19405 829678099842906f3dbfc82b4ee612d6 239 SMART SM00345 18 77 1.1E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS18080 4b01a71725b9fc85d8c96bbc610654ec 125 Pfam PF10956 Protein of unknown function (DUF2756) 1 99 4.5E-46 T 28-03-2018 IPR020158 Protein of unknown function DUF2756 WM46_RS18080 4b01a71725b9fc85d8c96bbc610654ec 125 ProDom PD059127 YHHA MEMBRANE OUTER PRECURSOR SIGNAL STY4259 ORFQ ECS4294 1 122 3.0E-13 T 28-03-2018 IPR020158 Protein of unknown function DUF2756 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 Gene3D G3DSA:3.40.50.980 189 362 1.9E-32 T 28-03-2018 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 Gene3D G3DSA:3.30.300.30 461 564 3.6E-14 T 28-03-2018 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 Pfam PF00501 AMP-binding enzyme 50 469 1.4E-77 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 Gene3D G3DSA:3.40.50.980 21 188 4.4E-31 T 28-03-2018 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 SUPERFAMILY SSF56801 22 356 3.27E-100 T 28-03-2018 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 SUPERFAMILY SSF56801 385 571 3.27E-100 T 28-03-2018 WM46_RS09355 3fc486fc765689fc4bb0d8c51c2ba00b 582 Gene3D G3DSA:2.30.38.10 371 460 1.4E-19 T 28-03-2018 WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 SMART SM00487 23 223 4.3E-59 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 Pfam PF00270 DEAD/DEAH box helicase 28 198 4.3E-47 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 4 428 49.607 T 28-03-2018 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 Gene3D G3DSA:3.40.50.300 226 444 2.1E-47 T 28-03-2018 WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 Gene3D G3DSA:3.40.50.300 1 225 1.7E-59 T 28-03-2018 WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 SMART SM00490 262 343 1.0E-30 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 Pfam PF00271 Helicase conserved C-terminal domain 235 343 4.1E-30 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS00355 b8461a4be558290b0345043c88cc1e02 444 SUPERFAMILY SSF52540 76 361 1.09E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 Pfam PF00672 HAMP domain 228 277 1.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 SMART SM00319 51 190 7.6E-29 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 19 44 3.5E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 379 406 3.5E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 3.5E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 302 331 3.5E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 456 485 3.5E-61 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 Gene3D G3DSA:1.10.287.950 333 532 8.9E-48 T 28-03-2018 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 Pfam PF02203 Tar ligand binding domain homologue 15 189 1.3E-34 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 SUPERFAMILY SSF47170 31 179 2.22E-26 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 Gene3D G3DSA:1.20.120.30 38 193 4.6E-27 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 SUPERFAMILY SSF58104 248 530 1.01E-73 T 28-03-2018 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 SMART SM00304 228 280 1.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 Gene3D G3DSA:1.10.287.950 194 332 3.9E-13 T 28-03-2018 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 339 496 1.4E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS06390 f85820bbba4de6eb93427d6ad5a62cc7 562 SMART SM00283 281 528 8.0E-87 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 Gene3D G3DSA:1.10.10.60 1 57 8.1E-17 T 28-03-2018 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 SUPERFAMILY SSF46689 57 106 1.39E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 Pfam PF12833 Helix-turn-helix domain 27 106 1.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 SUPERFAMILY SSF46689 4 56 1.5E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 Gene3D G3DSA:1.10.10.60 58 107 3.5E-14 T 28-03-2018 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 SMART SM00342 21 104 8.4E-33 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 2.4E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS21695 609c4a3ec9321fb9195e5d1d1f75692b 107 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 2.4E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.5E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.5E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 Gene3D G3DSA:3.40.1410.10 78 242 2.1E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 Gene3D G3DSA:1.10.10.10 1 76 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 Pfam PF07702 UTRA domain 100 231 8.6E-15 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 SMART SM00345 9 68 5.4E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 2.6E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 SUPERFAMILY SSF46785 3 72 1.18E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 SMART SM00866 91 232 6.3E-16 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS10475 9d172cb0de48dfe4a170634c556fc1ed 244 SUPERFAMILY SSF64288 56 238 4.71E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS14280 e662527f189345cf01aefb57a3f883c9 316 PIRSF PIRSF025414 1 316 4.1E-140 T 28-03-2018 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55 WM46_RS14280 e662527f189345cf01aefb57a3f883c9 316 Gene3D G3DSA:2.115.10.20 1 315 4.6E-62 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain WM46_RS14280 e662527f189345cf01aefb57a3f883c9 316 SUPERFAMILY SSF75005 5 311 4.11E-67 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain WM46_RS14280 e662527f189345cf01aefb57a3f883c9 316 Pfam PF04616 Glycosyl hydrolases family 43 5 306 9.3E-76 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 Gene3D G3DSA:3.40.50.300 2 188 5.6E-22 T 28-03-2018 WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 SUPERFAMILY SSF52540 4 214 1.1E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 SMART SM00487 3 195 4.4E-4 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 SUPERFAMILY SSF52540 124 185 1.01E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 SUPERFAMILY SSF52540 305 459 1.01E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 Gene3D G3DSA:3.40.50.300 299 458 1.1E-11 T 28-03-2018 WM46_RS13625 e9c928bf2f95758e81686193baf1d898 464 Pfam PF00176 SNF2 family N-terminal domain 30 265 4.2E-8 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 163 171 - T 28-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 SUPERFAMILY SSF56925 27 171 1.05E-33 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 Pfam PF13505 Outer membrane protein beta-barrel domain 9 171 2.1E-24 T 28-03-2018 IPR027385 Outer membrane protein beta-barrel WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 Gene3D G3DSA:2.40.160.20 22 171 1.5E-22 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 ProSitePatterns PS00694 Enterobacterial virulence outer membrane protein signature 1. 46 54 - T 28-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 45 57 1.1E-39 T 28-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 159 170 1.1E-39 T 28-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 132 153 1.1E-39 T 28-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 WM46_RS10390 b4f4f1208127da69a4f5ce6653715d7f 171 PRINTS PR00316 Enterobacterial virulence outer membrane protein signature 85 108 1.1E-39 T 28-03-2018 IPR000758 Virulence-related outer membrane protein GO:0009279 WM46_RS05710 e0e01c80077e5b2deacbe23325c8e626 337 Pfam PF00072 Response regulator receiver domain 10 119 2.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS05710 e0e01c80077e5b2deacbe23325c8e626 337 SMART SM00448 8 120 3.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS05710 e0e01c80077e5b2deacbe23325c8e626 337 Hamap MF_00958 Regulator of RpoS [rssB]. 1 337 54.97 T 28-03-2018 IPR028616 Regulator of RpoS WM46_RS05710 e0e01c80077e5b2deacbe23325c8e626 337 Gene3D G3DSA:3.40.50.2300 6 294 1.1E-33 T 28-03-2018 WM46_RS05710 e0e01c80077e5b2deacbe23325c8e626 337 SUPERFAMILY SSF52172 8 130 1.71E-32 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS16720 eb44fd71ec1af81d2683428797bae03c 298 Pfam PF01136 Peptidase family U32 98 204 1.0E-10 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS20780 cf983adaa9b2e5690d25e70602ff4850 252 Gene3D G3DSA:3.40.50.150 57 250 6.7E-31 T 28-03-2018 WM46_RS20780 cf983adaa9b2e5690d25e70602ff4850 252 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 3 248 37.732 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 WM46_RS20780 cf983adaa9b2e5690d25e70602ff4850 252 Pfam PF04445 Putative SAM-dependent methyltransferase 19 246 1.8E-105 T 28-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 WM46_RS20780 cf983adaa9b2e5690d25e70602ff4850 252 SUPERFAMILY SSF53335 14 246 1.66E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS20780 cf983adaa9b2e5690d25e70602ff4850 252 Gene3D G3DSA:3.40.1630.10 3 56 1.8E-22 T 28-03-2018 WM46_RS01405 aa12d0275c24ef733163d3703e89481b 240 PIRSF PIRSF039085 1 240 3.3E-115 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS01405 aa12d0275c24ef733163d3703e89481b 240 Pfam PF00005 ABC transporter 17 165 5.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS01405 aa12d0275c24ef733163d3703e89481b 240 SMART SM00382 26 213 7.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS01405 aa12d0275c24ef733163d3703e89481b 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS01405 aa12d0275c24ef733163d3703e89481b 240 SUPERFAMILY SSF52540 1 235 1.52E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01405 aa12d0275c24ef733163d3703e89481b 240 Gene3D G3DSA:3.40.50.300 1 239 3.3E-75 T 28-03-2018 WM46_RS13830 55e9c8e886fbf86333385c16872c4ad4 271 PIRSF PIRSF002854 1 271 1.7E-108 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS13830 55e9c8e886fbf86333385c16872c4ad4 271 Gene3D G3DSA:3.40.190.10 32 126 3.1E-22 T 28-03-2018 WM46_RS13830 55e9c8e886fbf86333385c16872c4ad4 271 SUPERFAMILY SSF53850 33 271 8.16E-84 T 28-03-2018 WM46_RS13830 55e9c8e886fbf86333385c16872c4ad4 271 Gene3D G3DSA:3.40.190.10 127 271 2.7E-50 T 28-03-2018 WM46_RS13830 55e9c8e886fbf86333385c16872c4ad4 271 Pfam PF03180 NLPA lipoprotein 33 271 1.2E-100 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS13830 55e9c8e886fbf86333385c16872c4ad4 271 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 14 271 5.6E-150 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS24495 c8f5148f02f5e0c05c980f48608de7f9 153 Pfam PF07670 Nucleoside recognition 27 90 8.4E-9 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 Pfam PF05034 Methylaspartate ammonia-lyase N-terminus 1 159 3.0E-71 T 28-03-2018 IPR022665 Methylaspartate ammonia-lyase, N-terminal KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 Gene3D G3DSA:3.30.390.10 2 162 1.7E-61 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 SUPERFAMILY SSF51604 163 411 6.68E-81 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 Pfam PF07476 Methylaspartate ammonia-lyase C-terminus 162 410 1.3E-119 T 28-03-2018 IPR022662 Methylaspartate ammonia-lyase, C-terminal KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 Gene3D G3DSA:3.20.20.120 165 413 6.0E-34 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 TIGRFAM TIGR01502 B_methylAsp_ase: methylaspartate ammonia-lyase 2 410 3.4E-165 T 28-03-2018 IPR006395 Methylaspartate ammonia-lyase GO:0050096 KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 SUPERFAMILY SSF54826 1 160 6.13E-65 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS10880 f7ca4b8253e218cd492db3f955ff0e68 413 PIRSF PIRSF017107 1 413 2.0E-247 T 28-03-2018 IPR006395 Methylaspartate ammonia-lyase GO:0050096 KEGG: 00630+4.3.1.2|KEGG: 00660+4.3.1.2|MetaCyc: PWY-5087|MetaCyc: PWY-6728 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 PRINTS PR01607 Apyrase family signature 252 272 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 PRINTS PR01607 Apyrase family signature 189 206 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 PRINTS PR01607 Apyrase family signature 11 29 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 PRINTS PR01607 Apyrase family signature 368 391 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 PRINTS PR01607 Apyrase family signature 224 247 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 PRINTS PR01607 Apyrase family signature 438 457 1.1E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 SUPERFAMILY SSF56300 11 315 1.69E-77 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 Pfam PF00149 Calcineurin-like phosphoesterase 14 241 6.2E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 Gene3D G3DSA:3.90.780.10 317 505 2.4E-42 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 SUPERFAMILY SSF55816 316 500 3.79E-41 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 Gene3D G3DSA:3.60.21.10 8 316 1.5E-80 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 Pfam PF02872 5'-nucleotidase, C-terminal domain 317 460 2.7E-30 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS01090 c0604997456d4913fc751c8736b1bd1b 506 ProSitePatterns PS00786 5'-nucleotidase signature 2. 91 102 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 ProSitePatterns PS00161 Isocitrate lyase signature. 193 198 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 SUPERFAMILY SSF51621 4 417 3.01E-157 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 Gene3D G3DSA:3.20.20.60 1 417 3.4E-154 T 28-03-2018 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 Pfam PF00463 Isocitrate lyase family 257 434 4.6E-50 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 Pfam PF00463 Isocitrate lyase family 8 255 1.0E-61 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 256 434 5.9E-93 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 255 7.1E-122 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM46_RS21345 9cbc54a487eb89b889016232ab7c14be 434 PIRSF PIRSF001362 1 434 2.1E-230 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 4.7E-60 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 Gene3D G3DSA:3.30.70.260 138 196 3.8E-24 T 28-03-2018 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 215 1.1E-72 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 Gene3D G3DSA:3.40.50.1360 1 137 5.7E-40 T 28-03-2018 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 SUPERFAMILY SSF100950 1 146 2.05E-46 T 28-03-2018 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 34.919 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS24150 784f4d4805c9a03c5c72bba7b81dd272 219 SUPERFAMILY SSF75445 127 198 3.27E-24 T 28-03-2018 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 395 648 3.0E-62 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 SUPERFAMILY SSF52279 395 464 5.89E-59 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 SUPERFAMILY SSF52279 495 651 5.89E-59 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 SMART SM01217 685 754 3.5E-30 T 28-03-2018 IPR026891 Fibronectin type III-like domain WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 Gene3D G3DSA:3.40.50.1700 380 648 7.5E-86 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 46 352 5.4E-100 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 Gene3D G3DSA:2.60.40.10 649 764 7.8E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 Gene3D G3DSA:3.20.20.300 32 375 1.6E-102 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 Pfam PF14310 Fibronectin type III-like domain 686 753 6.3E-22 T 28-03-2018 IPR026891 Fibronectin type III-like domain WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 SUPERFAMILY SSF51445 34 394 3.68E-97 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 120 139 8.0E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 166 182 8.0E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 203 219 8.0E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 101 117 8.0E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 PRINTS PR00133 Glycosyl hydrolase family 3 signature 273 291 8.0E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 WM46_RS02570 85b5f2e9638615492751c46956834f9a 765 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 273 290 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 WM46_RS22030 e55c1d6b1bf32a9ecfdb6bb6635859dd 198 SUPERFAMILY SSF89155 5 196 5.23E-46 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS22030 e55c1d6b1bf32a9ecfdb6bb6635859dd 198 Gene3D G3DSA:1.10.3480.10 3 197 1.3E-41 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS22030 e55c1d6b1bf32a9ecfdb6bb6635859dd 198 PIRSF PIRSF004690 1 197 8.1E-40 T 28-03-2018 IPR026269 Tat proofreading chaperone DmsD-type WM46_RS22030 e55c1d6b1bf32a9ecfdb6bb6635859dd 198 Pfam PF02613 Nitrate reductase delta subunit 55 152 2.3E-18 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS03245 0d8c764e187ddd453abc044b525474f6 87 SUPERFAMILY SSF141099 1 86 1.57E-24 T 28-03-2018 IPR015073 Atu1913-like WM46_RS03245 0d8c764e187ddd453abc044b525474f6 87 Gene3D G3DSA:4.10.1210.10 1 87 5.3E-29 T 28-03-2018 IPR015073 Atu1913-like WM46_RS03245 0d8c764e187ddd453abc044b525474f6 87 Pfam PF08980 Domain of unknown function (DUF1883) 1 85 5.1E-20 T 28-03-2018 IPR015073 Atu1913-like WM46_RS24960 3e81a188b61e7d2631e66cf99bfef528 148 TIGRFAM TIGR03391 FeS_syn_CsdE: cysteine desulfurase, sulfur acceptor subunit CsdE 7 144 2.8E-69 T 28-03-2018 IPR017763 Cysteine desulfurase, sulphur acceptor subunit CsdE WM46_RS24960 3e81a188b61e7d2631e66cf99bfef528 148 SUPERFAMILY SSF82649 3 144 1.52E-41 T 28-03-2018 WM46_RS24960 3e81a188b61e7d2631e66cf99bfef528 148 Gene3D G3DSA:3.90.1010.10 1 147 7.3E-43 T 28-03-2018 WM46_RS24960 3e81a188b61e7d2631e66cf99bfef528 148 Pfam PF02657 Fe-S metabolism associated domain 23 140 4.8E-37 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like WM46_RS17835 f57ddf00d29ddada7ec77d6fec219b9b 133 PIRSF PIRSF016821 6 133 1.1E-40 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 WM46_RS17835 f57ddf00d29ddada7ec77d6fec219b9b 133 SMART SM00363 9 72 1.0E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS17835 f57ddf00d29ddada7ec77d6fec219b9b 133 Gene3D G3DSA:3.10.290.10 2 105 5.7E-26 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS17835 f57ddf00d29ddada7ec77d6fec219b9b 133 SUPERFAMILY SSF55174 7 103 1.18E-31 T 28-03-2018 WM46_RS17835 f57ddf00d29ddada7ec77d6fec219b9b 133 Pfam PF01479 S4 domain 9 53 3.1E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 SUPERFAMILY SSF46785 8 81 9.38E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 SUPERFAMILY SSF55781 72 257 2.94E-50 T 28-03-2018 IPR029016 GAF domain-like WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 Pfam PF09339 IclR helix-turn-helix domain 8 58 4.0E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 SMART SM00346 6 97 7.7E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 Gene3D G3DSA:1.10.10.10 2 77 3.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 Pfam PF01614 Bacterial transcriptional regulator 126 252 2.4E-35 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS09285 7195ec3adba9345c9526742b74e708fc 265 Gene3D G3DSA:3.30.450.40 78 263 1.3E-51 T 28-03-2018 IPR029016 GAF domain-like WM46_RS08165 4883cb76adc8e95ebe675983100369de 191 Gene3D G3DSA:2.60.120.10 108 180 2.3E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS08165 4883cb76adc8e95ebe675983100369de 191 Hamap MF_01591 Protein Ves [ves]. 1 191 56.827 T 28-03-2018 IPR023482 Uncharacterised protein family Ves WM46_RS08165 4883cb76adc8e95ebe675983100369de 191 Gene3D G3DSA:2.60.120.10 6 107 5.5E-35 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS08165 4883cb76adc8e95ebe675983100369de 191 SUPERFAMILY SSF51182 1 184 3.2E-50 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS08165 4883cb76adc8e95ebe675983100369de 191 Pfam PF05962 HutD 5 175 1.3E-48 T 28-03-2018 IPR010282 Uncharacterised protein family HutD/Ves WM46_RS24270 eca205c688d2f4b67b8f1bd70aab4e7d 577 Gene3D G3DSA:3.90.1640.10 52 245 1.2E-22 T 28-03-2018 WM46_RS24270 eca205c688d2f4b67b8f1bd70aab4e7d 577 SUPERFAMILY SSF64182 48 465 8.63E-118 T 28-03-2018 WM46_RS24270 eca205c688d2f4b67b8f1bd70aab4e7d 577 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 23 573 7.5E-169 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 WM46_RS24270 eca205c688d2f4b67b8f1bd70aab4e7d 577 Pfam PF01368 DHH family 74 201 2.1E-8 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS24270 eca205c688d2f4b67b8f1bd70aab4e7d 577 Pfam PF02272 DHHA1 domain 322 452 4.1E-26 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 WM46_RS24885 cfda49ca43e258c357c65a81eb0a7f27 187 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 27 3.4E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS24885 cfda49ca43e258c357c65a81eb0a7f27 187 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 9.8E-8 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS24885 cfda49ca43e258c357c65a81eb0a7f27 187 PIRSF PIRSF004525 1 187 2.1E-62 T 28-03-2018 IPR016419 Prepilin peptidase-dependent protein B, predicted WM46_RS24885 cfda49ca43e258c357c65a81eb0a7f27 187 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS10410 4f8143507760d9524fc00de09b843916 248 SMART SM00079 26 245 1.4E-7 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 WM46_RS10410 4f8143507760d9524fc00de09b843916 248 Gene3D G3DSA:3.40.190.10 147 248 6.7E-18 T 28-03-2018 WM46_RS10410 4f8143507760d9524fc00de09b843916 248 Gene3D G3DSA:3.40.190.10 14 146 9.8E-39 T 28-03-2018 WM46_RS10410 4f8143507760d9524fc00de09b843916 248 SMART SM00062 26 246 2.2E-73 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS10410 4f8143507760d9524fc00de09b843916 248 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 48 61 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS10410 4f8143507760d9524fc00de09b843916 248 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 244 2.4E-70 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS10410 4f8143507760d9524fc00de09b843916 248 SUPERFAMILY SSF53850 8 246 1.48E-74 T 28-03-2018 WM46_RS18410 cdd9a537afde1114da3fd74ea9f24be4 309 Pfam PF01040 UbiA prenyltransferase family 27 277 1.2E-37 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 WM46_RS18410 cdd9a537afde1114da3fd74ea9f24be4 309 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 302 21.202 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 WM46_RS18410 cdd9a537afde1114da3fd74ea9f24be4 309 PIRSF PIRSF005355 1 307 3.4E-98 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 WM46_RS18410 cdd9a537afde1114da3fd74ea9f24be4 309 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 301 6.7E-146 T 28-03-2018 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 Gene3D G3DSA:3.40.640.10 99 277 3.6E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 397 7.6E-224 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 SUPERFAMILY SSF53383 4 396 5.24E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 395 54.015 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 Gene3D G3DSA:3.90.1150.10 278 397 3.8E-43 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 Gene3D G3DSA:3.90.1150.10 20 98 3.5E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS20240 5f70431abc6b6e85a85d058af6f2ca64 398 Pfam PF00155 Aminotransferase class I and II 43 387 8.1E-78 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 Gene3D G3DSA:3.40.47.10 261 413 1.5E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 SUPERFAMILY SSF53901 3 252 9.43E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 5.6E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 SUPERFAMILY SSF53901 215 412 1.75E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 PIRSF PIRSF000447 1 413 1.0E-202 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 411 2.5E-195 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 9.2E-64 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 Gene3D G3DSA:3.40.47.10 6 260 8.5E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site WM46_RS08670 0c24c04fa3c1e75e5f0954ca9f94dafd 413 SMART SM00825 Beta-ketoacyl synthase 6 413 5.7E-14 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM46_RS06485 d4448115bdd6ae94ef0d35a256cb6bdf 334 Pfam PF03595 Voltage-dependent anion channel 12 309 2.2E-39 T 28-03-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 WM46_RS06485 d4448115bdd6ae94ef0d35a256cb6bdf 334 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 13 316 4.3E-108 T 28-03-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 321 156.04 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 321 5.4E-162 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 Pfam PF04055 Radical SAM superfamily 91 251 3.2E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 25 73 9.6E-7 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 Gene3D G3DSA:3.20.20.70 28 309 3.6E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 SUPERFAMILY SSF102114 52 316 3.66E-67 T 28-03-2018 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 SMART SM00729 84 293 1.4E-15 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS11425 70379032bd795db0e24e2bb2b60fa95e 321 PIRSF PIRSF005963 2 321 3.6E-130 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 49.935 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 327 3.0E-119 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 SUPERFAMILY SSF55681 92 327 1.79E-81 T 28-03-2018 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 3.2E-107 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 Gene3D G3DSA:3.30.930.10 7 327 7.4E-91 T 28-03-2018 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 1.6E-26 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 WM46_RS08015 3baf7e493dd3384bc30d6282fc2ecf0b 327 SUPERFAMILY SSF46589 14 99 1.67E-22 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 SUPERFAMILY SSF56935 22 376 9.68E-79 T 28-03-2018 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 94 116 9.3E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 250 267 9.3E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 9.3E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 279 298 9.3E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 148 170 9.3E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 9.3E-73 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 328 344 - T 28-03-2018 IPR013793 Porin, Gram-negative type, conserved site WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 244 256 4.8E-20 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 328 345 4.8E-20 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 150 161 4.8E-20 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 94 104 4.8E-20 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 4.8E-20 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 Gene3D G3DSA:2.40.160.10 32 376 3.6E-50 T 28-03-2018 WM46_RS02085 499d129eed5694f251fe4567bae913e5 376 Pfam PF00267 Gram-negative porin 27 376 2.4E-149 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS00985 8671069e1cce7c2d0eecda88cadf6824 467 Gene3D G3DSA:3.40.605.10 10 252 6.2E-31 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS00985 8671069e1cce7c2d0eecda88cadf6824 467 Gene3D G3DSA:3.40.309.10 253 425 1.9E-27 T 28-03-2018 WM46_RS00985 8671069e1cce7c2d0eecda88cadf6824 467 SUPERFAMILY SSF53720 34 458 1.7E-63 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS00985 8671069e1cce7c2d0eecda88cadf6824 467 Pfam PF00171 Aldehyde dehydrogenase family 34 422 8.7E-32 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS00985 8671069e1cce7c2d0eecda88cadf6824 467 PIRSF PIRSF036410 1 467 1.3E-212 T 28-03-2018 IPR012408 Acetaldehyde/propionaldehyde dehydrogenase, EutE/PduP-related WM46_RS13905 a43ece403a1b0de37c90ac1b7a84b679 198 Pfam PF01351 Ribonuclease HII 13 189 2.9E-38 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain WM46_RS13905 a43ece403a1b0de37c90ac1b7a84b679 198 Gene3D G3DSA:3.30.420.10 3 198 2.4E-69 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13905 a43ece403a1b0de37c90ac1b7a84b679 198 SUPERFAMILY SSF53098 3 195 4.1E-70 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13905 a43ece403a1b0de37c90ac1b7a84b679 198 Hamap MF_00052_B Ribonuclease HII [rnhB]. 11 190 39.708 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Gene3D G3DSA:3.30.70.400 162 227 2.0E-24 T 28-03-2018 IPR015162 CheY binding WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SMART SM01231 280 343 4.3E-21 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Gene3D G3DSA:1.10.287.560 280 344 1.5E-19 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SUPERFAMILY SSF55052 163 227 1.15E-17 T 28-03-2018 IPR015162 CheY binding WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SMART SM00387 388 528 6.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Gene3D G3DSA:1.20.120.160 1 145 4.5E-36 T 28-03-2018 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Pfam PF01627 Hpt domain 8 104 4.8E-20 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Gene3D G3DSA:2.30.30.40 614 659 1.1E-21 T 28-03-2018 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SUPERFAMILY SSF55874 346 526 2.1E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Gene3D G3DSA:2.40.50.180 544 613 3.7E-12 T 28-03-2018 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 2.4E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 2.4E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 2.4E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 482 2.4E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SMART SM00260 520 660 1.6E-45 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SUPERFAMILY SSF47226 5 126 1.02E-32 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SMART SM00073 5 102 4.3E-34 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SUPERFAMILY SSF47384 281 344 3.81E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 281 343 1.1E-17 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Gene3D G3DSA:3.30.565.10 346 534 2.8E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Pfam PF01584 CheW-like domain 533 659 1.9E-26 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 391 527 2.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 SUPERFAMILY SSF50341 527 659 2.62E-31 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS04125 2f93687d0ad42575335e9444f604627a 673 Pfam PF09078 CheY binding 164 226 1.0E-19 T 28-03-2018 IPR015162 CheY binding WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 SMART SM00830 9 89 6.7E-31 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 Gene3D G3DSA:1.10.3660.10 249 372 5.2E-33 T 28-03-2018 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 Gene3D G3DSA:3.40.50.720 84 247 1.0E-26 T 28-03-2018 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 PIRSF PIRSF001499 1 373 1.5E-184 T 28-03-2018 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 SUPERFAMILY SSF48600 4 88 2.38E-23 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 Pfam PF01817 Chorismate mutase type II 9 86 9.0E-20 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 Gene3D G3DSA:1.20.59.10 3 83 4.4E-24 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 Pfam PF02153 Prephenate dehydrogenase 137 344 6.7E-30 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 SUPERFAMILY SSF48179 241 366 4.31E-42 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 TIGRFAM TIGR01799 CM_T: chorismate mutase 5 87 3.7E-45 T 28-03-2018 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626 WM46_RS00240 f988c4cd52435461e131e23f9032de7e 373 SUPERFAMILY SSF51735 91 238 2.13E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20700 8bd79fe701adf6fe217129d221184ccc 309 Gene3D G3DSA:3.40.1190.20 1 309 3.8E-60 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS20700 8bd79fe701adf6fe217129d221184ccc 309 Pfam PF00294 pfkB family carbohydrate kinase 3 304 2.7E-72 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS20700 8bd79fe701adf6fe217129d221184ccc 309 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS20700 8bd79fe701adf6fe217129d221184ccc 309 SUPERFAMILY SSF53613 2 303 2.49E-74 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 SUPERFAMILY SSF47384 240 324 1.26E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 SMART SM00304 203 256 2.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 475 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 1.6E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 Gene3D G3DSA:1.10.287.130 247 319 8.5E-11 T 28-03-2018 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 SUPERFAMILY SSF55874 312 476 4.71E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 322 3.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 SMART SM00387 367 478 5.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 SMART SM00388 257 323 5.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 Gene3D G3DSA:3.30.565.10 327 479 9.1E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 9 475 1.6E-155 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 WM46_RS11865 c5dce1c6c9e5717826d9df391bebe17f 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 477 1.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02595 3f218e36c82849980fbb26cc59f2217e 35 Hamap MF_01362 UPF0387 membrane protein YohO [yohO]. 1 35 15.68 T 28-03-2018 IPR020870 Uncharacterised protein family UPF0387, membrane GO:0005886 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 SUPERFAMILY SSF53681 118 229 1.54E-30 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 Gene3D G3DSA:3.40.50.1860 1 118 3.8E-29 T 28-03-2018 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 224 1.2E-54 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 Gene3D G3DSA:3.40.50.1860 119 216 3.9E-22 T 28-03-2018 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 229 4.3E-62 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 SUPERFAMILY SSF53681 1 116 2.13E-35 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 193 203 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24785 86045c05fbbde595bba43b2abf673d51 230 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 Gene3D G3DSA:3.20.20.360 81 414 1.3E-108 T 28-03-2018 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 Pfam PF01274 Malate synthase 13 532 2.8E-211 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 SUPERFAMILY SSF51645 20 532 4.32E-186 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 PIRSF PIRSF001363 2 533 1.7E-248 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 24 532 1.1E-248 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 WM46_RS21340 b85953e7dee1f429215d331dff5e3bba 533 Gene3D G3DSA:1.20.1220.12 415 532 7.7E-48 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Gene3D G3DSA:3.30.70.240 401 481 8.1E-19 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 SUPERFAMILY SSF50447 151 299 9.5E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 8.4E-294 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Gene3D G3DSA:3.40.50.300 2 67 1.0E-10 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Pfam PF00679 Elongation factor G C-terminus 397 477 1.2E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 SUPERFAMILY SSF54980 302 387 3.96E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 SUPERFAMILY SSF52540 3 207 1.87E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Gene3D G3DSA:2.40.50.250 483 573 4.3E-38 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 PRINTS PR00315 GTP-binding elongation factor signature 87 98 9.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 PRINTS PR00315 GTP-binding elongation factor signature 123 132 9.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 PRINTS PR00315 GTP-binding elongation factor signature 71 81 9.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 PRINTS PR00315 GTP-binding elongation factor signature 51 59 9.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 PRINTS PR00315 GTP-binding elongation factor signature 7 20 9.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Gene3D G3DSA:3.40.50.300 68 186 1.0E-29 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 134 8.7E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 SUPERFAMILY SSF54980 398 512 2.4E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Gene3D G3DSA:3.30.70.870 302 400 1.1E-31 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Gene3D G3DSA:2.40.30.10 187 300 5.1E-22 T 28-03-2018 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 8.2E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS18825 4cc4c1ce5e45c84c98366d8df29a5327 607 Pfam PF03144 Elongation factor Tu domain 2 219 289 3.3E-11 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 4.4E-123 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 PIRSF PIRSF001365 1 292 1.1E-98 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 Gene3D G3DSA:3.20.20.70 1 292 6.2E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 SUPERFAMILY SSF51569 1 292 3.77E-100 T 28-03-2018 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 5.0E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 5.0E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 5.0E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 5.0E-35 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 288 6.1E-126 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 66.023 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS00850 45586536df6c6a6f98d84a7b78e52ad0 292 SMART SM01130 1 290 1.1E-142 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 Gene3D G3DSA:1.10.10.60 212 259 4.8E-7 T 28-03-2018 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 251 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 Gene3D G3DSA:1.10.10.60 165 211 6.9E-8 T 28-03-2018 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 Pfam PF12833 Helix-turn-helix domain 179 256 5.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 239 7.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 255 7.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 Gene3D G3DSA:2.60.120.10 4 164 2.2E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 SUPERFAMILY SSF46689 211 256 4.93E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 Pfam PF02311 AraC-like ligand binding domain 21 94 1.1E-4 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 SUPERFAMILY SSF51182 14 182 2.08E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS08390 d35f697431fd3becd4ba81e546c29b18 264 SMART SM00342 172 255 2.1E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21415 83ef44f7b815548e4e67db723523df7e 164 Pfam PF03830 PTS system sorbose subfamily IIB component 3 149 1.5E-52 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS21415 83ef44f7b815548e4e67db723523df7e 164 Gene3D G3DSA:3.40.35.10 2 158 1.8E-58 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS21415 83ef44f7b815548e4e67db723523df7e 164 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 2 151 1.4E-68 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 WM46_RS21415 83ef44f7b815548e4e67db723523df7e 164 SUPERFAMILY SSF52728 1 160 2.09E-54 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 526 539 8.5E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 238 261 8.5E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 8.5E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 401 416 8.5E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 561 570 8.5E-33 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Pfam PF06827 Zinc finger found in FPG and IleRS 898 926 9.2E-9 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 843 0.0 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 640 1.3E-230 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 SUPERFAMILY SSF47323 652 929 1.81E-77 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Pfam PF08264 Anticodon-binding domain of tRNA 685 840 3.5E-28 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Gene3D G3DSA:3.40.50.620 386 590 2.9E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Gene3D G3DSA:3.90.740.10 189 385 1.8E-58 T 28-03-2018 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Gene3D G3DSA:3.30.2320.20 802 896 1.4E-24 T 28-03-2018 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Gene3D G3DSA:1.10.730.10 591 794 2.7E-46 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 SUPERFAMILY SSF52374 403 648 1.18E-137 T 28-03-2018 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 SUPERFAMILY SSF52374 3 202 1.18E-137 T 28-03-2018 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 SUPERFAMILY SSF50677 204 403 3.77E-54 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 929 21.435 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 WM46_RS14700 648528bb28f180ebad346ae022e3f5dc 938 Gene3D G3DSA:3.40.50.620 42 124 4.4E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 Pfam PF08220 DeoR-like helix-turn-helix domain 11 66 2.5E-21 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 SUPERFAMILY SSF46785 9 75 7.34E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 Gene3D G3DSA:3.40.50.1360 75 258 1.1E-36 T 28-03-2018 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 SUPERFAMILY SSF100950 79 236 9.42E-26 T 28-03-2018 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 3.7E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 3.7E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 SMART SM00420 11 63 3.2E-22 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 Pfam PF00455 DeoR C terminal sensor domain 80 237 1.3E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 SMART SM01134 77 238 1.7E-59 T 28-03-2018 WM46_RS18770 665e7c427f13abfd7dca6f23afeb5223 267 Gene3D G3DSA:1.10.10.10 6 74 5.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 Pfam PF07690 Major Facilitator Superfamily 35 396 3.6E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 413 1.7E-152 T 28-03-2018 WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 Gene3D G3DSA:1.20.1250.20 19 212 7.1E-31 T 28-03-2018 WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 PIRSF PIRSF002808 6 442 3.1E-153 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 Gene3D G3DSA:1.20.1250.20 237 442 7.2E-27 T 28-03-2018 WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 SUPERFAMILY SSF103473 17 438 1.14E-76 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19845 3217e13d3548b3f8ef260b749dbef785 442 ProSitePatterns PS00942 glpT family of transporters signature. 151 167 - T 28-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 WM46_RS16470 c3da69237caf1e94794fdc3f84b05bc5 437 Pfam PF03313 Serine dehydratase alpha chain 179 429 1.3E-45 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit WM46_RS16470 c3da69237caf1e94794fdc3f84b05bc5 437 Hamap MF_01845 UPF0597 protein YhaM [yhaM]. 9 434 34.217 T 28-03-2018 IPR021144 Uncharacterised protein family UPF0597 WM46_RS16470 c3da69237caf1e94794fdc3f84b05bc5 437 PIRSF PIRSF006054 5 436 2.1E-170 T 28-03-2018 IPR021144 Uncharacterised protein family UPF0597 WM46_RS23125 da77acc62d06d197a27d07fc38668980 577 Gene3D G3DSA:3.10.20.310 103 188 1.3E-10 T 28-03-2018 WM46_RS23125 da77acc62d06d197a27d07fc38668980 577 Pfam PF01103 Surface antigen 282 574 1.9E-30 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 WM46_RS23125 da77acc62d06d197a27d07fc38668980 577 Pfam PF17243 POTRA domain TamA domain 1 26 100 2.1E-21 T 28-03-2018 IPR035243 TamA, POTRA domain 1 WM46_RS23125 da77acc62d06d197a27d07fc38668980 577 Gene3D G3DSA:2.40.160.50 221 576 3.0E-60 T 28-03-2018 WM46_RS23125 da77acc62d06d197a27d07fc38668980 577 Gene3D G3DSA:3.10.20.310 24 102 0.4 T 28-03-2018 WM46_RS23125 da77acc62d06d197a27d07fc38668980 577 Pfam PF07244 Surface antigen variable number repeat 189 246 1.3E-7 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 SUPERFAMILY SSF52317 254 456 3.15E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 494 2.9E-162 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 Pfam PF13500 AAA domain 3 227 1.8E-21 T 28-03-2018 WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 Gene3D G3DSA:3.40.50.880 252 497 3.2E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 502 188.805 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 SUPERFAMILY SSF52540 1 228 1.31E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 447 4.8E-61 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 WM46_RS03625 c77c9ef22000ec9b3a6b2d8eb2e6930b 506 Gene3D G3DSA:3.40.50.300 1 240 2.2E-49 T 28-03-2018 WM46_RS18550 00c5b1a80e651d0e5f8fbc56bc1fe25a 344 Pfam PF06379 L-rhamnose-proton symport protein (RhaT) 1 344 1.3E-220 T 28-03-2018 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 WM46_RS18550 00c5b1a80e651d0e5f8fbc56bc1fe25a 344 Hamap MF_01532 L-rhamnose-proton symporter [rhaT]. 1 344 47.108 T 28-03-2018 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 WM46_RS18550 00c5b1a80e651d0e5f8fbc56bc1fe25a 344 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 7 342 1.6E-112 T 28-03-2018 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 Gene3D G3DSA:1.20.1250.20 11 206 9.2E-13 T 28-03-2018 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 Pfam PF01306 LacY proton/sugar symporter 6 404 2.2E-108 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 10 401 5.2E-108 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 SUPERFAMILY SSF103473 13 401 3.92E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 Gene3D G3DSA:1.20.1250.20 207 409 2.3E-20 T 28-03-2018 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 106 128 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 71 100 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 346 366 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 214 242 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 315 334 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 284 310 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 148 166 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS16090 be1f7decab424dd9e8688c3825892212 422 PRINTS PR00174 LacY proton/sugar symporter family signature 260 281 1.6E-63 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS03940 d19abac75d9417fb3cfe6c900f525fbd 182 Hamap MF_01437 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [pgsA]. 1 182 34.522 T 28-03-2018 IPR023762 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, bacterial GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM46_RS03940 d19abac75d9417fb3cfe6c900f525fbd 182 PIRSF PIRSF000847 1 177 7.0E-43 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM46_RS03940 d19abac75d9417fb3cfe6c900f525fbd 182 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 180 4.4E-64 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM46_RS03940 d19abac75d9417fb3cfe6c900f525fbd 182 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 49 71 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM46_RS03940 d19abac75d9417fb3cfe6c900f525fbd 182 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 71 1.8E-17 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 SUPERFAMILY SSF103473 8 460 3.27E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 Gene3D G3DSA:1.20.1250.20 246 474 1.9E-32 T 28-03-2018 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 ProSitePatterns PS00217 Sugar transport proteins signature 2. 113 138 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 5 457 2.0E-108 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 Pfam PF00083 Sugar (and other) transporter 16 460 2.7E-111 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 ProSitePatterns PS00216 Sugar transport proteins signature 1. 322 339 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 88 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 Gene3D G3DSA:1.20.1250.20 2 224 4.0E-38 T 28-03-2018 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 PRINTS PR00171 Sugar transporter signature 278 288 1.0E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 PRINTS PR00171 Sugar transporter signature 24 34 1.0E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 PRINTS PR00171 Sugar transporter signature 108 127 1.0E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 PRINTS PR00171 Sugar transporter signature 363 384 1.0E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS00530 b2a0bcec463735c01a34f9538ac5afdf 479 PRINTS PR00171 Sugar transporter signature 386 398 1.0E-20 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15095 aaa54899f6c50d0cb01d634df7a6c009 197 Gene3D G3DSA:3.90.950.10 1 197 1.7E-81 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS15095 aaa54899f6c50d0cb01d634df7a6c009 197 Pfam PF01725 Ham1 family 4 192 6.4E-57 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 WM46_RS15095 aaa54899f6c50d0cb01d634df7a6c009 197 SUPERFAMILY SSF52972 1 195 4.19E-75 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS15095 aaa54899f6c50d0cb01d634df7a6c009 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 194 2.5E-70 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 WM46_RS15095 aaa54899f6c50d0cb01d634df7a6c009 197 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 51.843 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 Gene3D G3DSA:3.50.50.60 3 294 2.9E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 Gene3D G3DSA:3.50.50.60 302 430 5.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 SUPERFAMILY SSF46977 452 588 1.57E-46 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 Pfam PF02910 Fumarate reductase flavoprotein C-term 460 588 1.6E-36 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 7.4E-5 T 28-03-2018 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 390 7.4E-5 T 28-03-2018 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 Gene3D G3DSA:4.10.80.40 541 588 3.4E-12 T 28-03-2018 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 Pfam PF00890 FAD binding domain 9 405 2.3E-118 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 588 8.6E-278 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 588 1.2E-241 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 SUPERFAMILY SSF56425 236 356 4.78E-42 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 Gene3D G3DSA:1.20.58.100 431 540 6.6E-37 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 SUPERFAMILY SSF51905 4 259 4.99E-75 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 SUPERFAMILY SSF51905 359 432 4.99E-75 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10995 5726a161368e21808a2965dfc71e5d58 588 PIRSF PIRSF000171 1 579 9.9E-47 T 28-03-2018 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SUPERFAMILY SSF48452 293 432 8.34E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Gene3D G3DSA:1.25.40.10 165 354 3.6E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SUPERFAMILY SSF48452 466 545 1.09E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SUPERFAMILY SSF48452 609 660 1.09E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Gene3D G3DSA:1.25.40.10 706 781 0.28 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Gene3D G3DSA:1.25.40.10 29 164 1.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Pfam PF14559 Tetratricopeptide repeat 615 669 9.5E-9 T 28-03-2018 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Gene3D G3DSA:1.25.40.10 455 589 1.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Pfam PF05420 Cellulose synthase operon protein C C-terminus (BCSC_C) 802 1144 9.0E-119 T 28-03-2018 IPR008410 Cellulose synthase operon C, C-terminal GO:0019867|GO:0030244 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SUPERFAMILY SSF48452 117 235 5.06E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SUPERFAMILY SSF48452 286 335 5.06E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SUPERFAMILY SSF48452 578 738 2.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 303 336 0.006 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 461 494 94.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 603 636 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 351 384 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 711 744 310.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 385 418 0.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 SMART SM00028 671 704 330.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Gene3D G3DSA:1.25.40.10 355 439 2.6E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Pfam PF13432 Tetratricopeptide repeat 274 336 5.8E-7 T 28-03-2018 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Pfam PF13432 Tetratricopeptide repeat 389 445 1.9E-4 T 28-03-2018 WM46_RS20675 2a0eeacb2d07f5ecb86493bbb5b94a8f 1165 Gene3D G3DSA:1.25.40.10 590 705 7.0E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 266 278 2.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 287 302 2.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 118 131 2.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 302 313 2.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 PRINTS PR00046 Major sigma-70 factor signature 142 150 2.5E-27 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 SUPERFAMILY SSF88659 225 323 1.46E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 SUPERFAMILY SSF88946 56 164 2.75E-45 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF04545 Sigma-70, region 4 262 315 2.7E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 SUPERFAMILY SSF88659 167 241 8.72E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF00140 Sigma-70 factor, region 1.2 56 88 2.9E-11 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF04539 Sigma-70 region 3 174 248 1.2E-20 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Gene3D G3DSA:1.10.601.10 2 163 6.4E-59 T 28-03-2018 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 48 328 4.4E-145 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 118 131 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 3 328 40.0 T 28-03-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Gene3D G3DSA:1.10.10.10 164 214 1.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Pfam PF04542 Sigma-70 region 2 94 163 3.6E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 Gene3D G3DSA:1.10.10.10 256 324 4.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 287 313 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25295 58216af11ca71371bf7a8801dbe9637f 330 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 90 317 5.5E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS21230 58cffbc8cba8811ba469daf01950d33d 252 Gene3D G3DSA:3.40.50.720 1 245 2.0E-71 T 28-03-2018 WM46_RS21230 58cffbc8cba8811ba469daf01950d33d 252 Pfam PF00899 ThiF family 9 240 1.5E-64 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 WM46_RS21230 58cffbc8cba8811ba469daf01950d33d 252 SUPERFAMILY SSF69572 2 246 2.09E-80 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 SUPERFAMILY SSF143034 2 64 3.01E-23 T 28-03-2018 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.3E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.3E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.3E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 Pfam PF01632 Ribosomal protein L35 2 60 6.6E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.094 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM46_RS08030 3b3a2efcf834d34ecd85caba08a7954a 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.6E-27 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 Pfam PF00267 Gram-negative porin 27 396 5.8E-151 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 Gene3D G3DSA:2.40.160.10 32 396 1.4E-49 T 28-03-2018 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 152 163 1.2E-14 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 95 105 1.2E-14 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 1.2E-14 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 347 364 1.2E-14 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 249 261 1.2E-14 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 347 363 - T 28-03-2018 IPR013793 Porin, Gram-negative type, conserved site WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00183 E.coli/Salmonella-type porin signature 95 117 2.3E-67 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00183 E.coli/Salmonella-type porin signature 293 312 2.3E-67 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 2.3E-67 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00183 E.coli/Salmonella-type porin signature 150 172 2.3E-67 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 2.3E-67 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 PRINTS PR00183 E.coli/Salmonella-type porin signature 255 272 2.3E-67 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS03710 1dea5791ad8531076c7a5781ba4d36ea 396 SUPERFAMILY SSF56935 22 396 4.71E-78 T 28-03-2018 WM46_RS15145 8c07f6b411ab5c0fa2e57de93ab4e0ef 360 Gene3D G3DSA:1.10.530.10 183 357 3.6E-35 T 28-03-2018 WM46_RS15145 8c07f6b411ab5c0fa2e57de93ab4e0ef 360 Pfam PF11873 Domain of unknown function (DUF3393) 3 192 2.2E-74 T 28-03-2018 IPR024570 Murein transglycosylase-C, N-terminal WM46_RS15145 8c07f6b411ab5c0fa2e57de93ab4e0ef 360 SUPERFAMILY SSF53955 192 358 7.6E-37 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS15145 8c07f6b411ab5c0fa2e57de93ab4e0ef 360 Pfam PF01464 Transglycosylase SLT domain 196 319 6.9E-33 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS15145 8c07f6b411ab5c0fa2e57de93ab4e0ef 360 Hamap MF_01616 Membrane-bound lytic murein transglycosylase C [mltC]. 1 359 64.785 T 28-03-2018 IPR023664 Murein transglycosylase-C GO:0009279|GO:0016798|GO:0016998 WM46_RS15145 8c07f6b411ab5c0fa2e57de93ab4e0ef 360 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 214 242 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 509 0.0 T 28-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 Gene3D G3DSA:3.40.50.720 1 195 1.3E-52 T 28-03-2018 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 SUPERFAMILY SSF51735 137 317 5.01E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 SMART SM01002 146 311 5.4E-84 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 28-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 PIRSF PIRSF000203 1 508 9.4E-285 T 28-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 368 1.5E-75 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 SUPERFAMILY SSF52283 1 168 2.38E-57 T 28-03-2018 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 SMART SM01003 4 137 8.0E-76 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 7.3E-52 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 426 508 9.0E-36 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM46_RS07335 0a953fb1f9969b82ab25ee1538848c90 509 Gene3D G3DSA:3.40.50.720 196 377 9.0E-57 T 28-03-2018 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Gene3D G3DSA:1.10.8.70 317 361 1.1E-11 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 305 1.2E-120 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Gene3D G3DSA:1.10.10.350 366 471 7.0E-25 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Gene3D G3DSA:3.40.50.620 3 118 1.4E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 461 32.902 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 SUPERFAMILY SSF48163 299 461 3.27E-45 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 462 9.8E-209 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 SUPERFAMILY SSF52374 3 298 1.82E-112 T 28-03-2018 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 5.9E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 5.9E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 5.9E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 5.9E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 5.9E-28 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Gene3D G3DSA:1.10.1160.10 232 314 1.1E-34 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 WM46_RS01235 eae7084b3026b95c2eeb4988fa466895 471 Gene3D G3DSA:3.40.50.620 119 230 1.1E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Gene3D G3DSA:3.30.2090.10 180 275 3.8E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82714 725 812 1.11E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82866 809 1033 3.14E-44 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1030 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82693 567 671 7.85E-33 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Gene3D G3DSA:3.30.70.1440 674 771 1.3E-19 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Gene3D G3DSA:1.20.1640.10 827 1033 1.2E-37 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Gene3D G3DSA:3.30.70.1430 38 140 1.1E-29 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 623 637 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 554 571 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 5.8E-115 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82693 135 182 2.67E-26 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82693 274 330 2.67E-26 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Gene3D G3DSA:3.30.70.1430 569 670 7.9E-21 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1047 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82693 38 132 1.2E-27 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82714 182 271 2.35E-21 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 SUPERFAMILY SSF82866 296 497 1.26E-47 T 28-03-2018 WM46_RS12440 4c525e3512cba9ffb1cd51aa2aa9537c 1049 Gene3D G3DSA:1.20.1640.10 287 510 4.2E-44 T 28-03-2018 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Gene3D G3DSA:3.30.750.80 392 491 7.7E-9 T 28-03-2018 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 SUPERFAMILY SSF53335 396 698 5.28E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 474 658 3.4E-20 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 702 32.788 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Pfam PF02926 THUMP domain 22 153 1.3E-20 T 28-03-2018 IPR004114 THUMP domain GO:0003723 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Gene3D G3DSA:3.40.50.150 169 391 1.3E-32 T 28-03-2018 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 303 315 3.0E-5 T 28-03-2018 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 193 207 3.0E-5 T 28-03-2018 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 SMART SM00981 56 154 1.7E-19 T 28-03-2018 IPR004114 THUMP domain GO:0003723 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Pfam PF01170 Putative RNA methylase family UPF0020 162 375 1.5E-64 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 SUPERFAMILY SSF53335 258 373 4.22E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 SUPERFAMILY SSF53335 148 217 4.22E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 Gene3D G3DSA:3.40.50.150 492 702 2.7E-43 T 28-03-2018 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS09690 b860dd844a5869851e2fead4456949ab 702 PIRSF PIRSF037618 1 702 1.7E-296 T 28-03-2018 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS16635 67e8b59f9bc9cd821b37893dadf5855c 158 Pfam PF03830 PTS system sorbose subfamily IIB component 6 153 3.4E-48 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS16635 67e8b59f9bc9cd821b37893dadf5855c 158 Gene3D G3DSA:3.40.35.10 5 158 5.0E-55 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS16635 67e8b59f9bc9cd821b37893dadf5855c 158 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 5 154 9.5E-70 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 WM46_RS16635 67e8b59f9bc9cd821b37893dadf5855c 158 SUPERFAMILY SSF52728 5 155 1.07E-47 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 8.1E-29 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 Gene3D G3DSA:3.20.20.60 167 321 5.4E-63 T 28-03-2018 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 Gene3D G3DSA:2.40.33.10 78 166 2.0E-31 T 28-03-2018 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 SUPERFAMILY SSF51621 1 74 6.28E-100 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 SUPERFAMILY SSF51621 156 339 6.28E-100 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 SUPERFAMILY SSF52935 323 469 5.36E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 Gene3D G3DSA:3.40.1380.20 322 470 7.1E-46 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 SUPERFAMILY SSF50800 70 166 1.92E-29 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 Pfam PF00224 Pyruvate kinase, barrel domain 1 341 2.9E-151 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 217 243 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 59 75 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 186 200 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 294 312 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 313 329 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 244 268 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 PRINTS PR01050 Pyruvate kinase family signature 269 293 8.5E-77 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 4.5E-190 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS07810 4ddae74a951f85f4e4126fb1290a8854 470 Gene3D G3DSA:3.20.20.60 1 77 2.4E-18 T 28-03-2018 WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 SUPERFAMILY SSF51161 1 256 1.11E-79 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 3.5E-25 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 Gene3D G3DSA:2.160.10.10 87 257 8.6E-36 T 28-03-2018 WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 Gene3D G3DSA:1.10.166.10 3 69 3.6E-28 T 28-03-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 6.2E-13 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 58.63 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3 273 6.4E-164 T 28-03-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 133 166 0.0019 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13995 1f9797fb6e65d70705fa7d9971fc5701 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS20440 0d76018610c0e2d4d4a7a6e18530e94b 393 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 383 7.2E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS20440 0d76018610c0e2d4d4a7a6e18530e94b 393 Gene3D G3DSA:1.10.3470.10 49 389 3.4E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 137 143 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 21 167 39.868 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 Gene3D G3DSA:1.10.10.10 84 170 6.8E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 87 166 8.9E-39 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 83 1.9E-16 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 SUPERFAMILY SSF46767 86 169 5.36E-34 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 88 167 2.8E-35 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 WM46_RS06165 65eb1c5ddf63ba49acac2aed57e6e84d 171 SUPERFAMILY SSF53155 9 91 3.65E-5 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 Gene3D G3DSA:3.40.50.880 152 379 1.6E-68 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 3.2E-11 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 3.2E-11 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 3.2E-11 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 3.5E-52 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 375 5.2E-153 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 2.5E-40 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 2.5E-40 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 2.5E-40 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 2.5E-40 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 2.5E-40 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 SMART SM01097 3 133 7.1E-91 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 SUPERFAMILY SSF52317 153 374 5.35E-65 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 Gene3D G3DSA:3.50.30.20 2 151 3.0E-63 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 378 48.784 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 SUPERFAMILY SSF52021 3 144 3.53E-57 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 Pfam PF00117 Glutamine amidotransferase class-I 197 372 5.9E-50 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00097 Anthranilate synthase component II signature 264 275 1.1E-5 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00097 Anthranilate synthase component II signature 236 245 1.1E-5 T 28-03-2018 WM46_RS14670 e413968c16becd61ed14b3b13c91efff 382 PRINTS PR00097 Anthranilate synthase component II signature 349 362 1.1E-5 T 28-03-2018 WM46_RS21995 1679a4992e190243e5378c17ba187891 239 PIRSF PIRSF006171 1 230 4.7E-82 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 WM46_RS21995 1679a4992e190243e5378c17ba187891 239 Gene3D G3DSA:1.10.10.10 143 235 1.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21995 1679a4992e190243e5378c17ba187891 239 Gene3D G3DSA:3.40.50.2300 1 142 4.4E-25 T 28-03-2018 WM46_RS21995 1679a4992e190243e5378c17ba187891 239 Pfam PF00072 Response regulator receiver domain 4 117 2.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS21995 1679a4992e190243e5378c17ba187891 239 SUPERFAMILY SSF52172 1 137 1.99E-28 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS21995 1679a4992e190243e5378c17ba187891 239 SMART SM00448 2 117 1.2E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 SUPERFAMILY SSF54999 5 101 1.26E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.353 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.0E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 SMART SM01403 7 101 1.0E-56 T 28-03-2018 IPR027486 Ribosomal protein S10 domain WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 2.1E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.2E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.2E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.2E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17550 45d53e98b9ae88d2567b52bea3a6f87c 103 Gene3D G3DSA:3.30.70.600 3 102 1.4E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 653 1.0E-21 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF81653 127 236 1.7E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 95 191 4.3E-18 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 190 359 3.3E-23 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 608 732 4.0E-36 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Gene3D G3DSA:3.40.1110.10 301 545 6.0E-35 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 570 7.4E-41 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 658 7.4E-41 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 174 188 7.4E-41 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 549 7.4E-41 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 663 675 7.4E-41 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 337 351 7.4E-41 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 496 514 1.2E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 611 627 1.2E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 671 696 1.2E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 639 655 1.2E-20 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Gene3D G3DSA:1.20.1110.10 591 902 3.8E-84 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Gene3D G3DSA:2.70.150.10 25 237 2.0E-46 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF56784 335 355 1.18E-60 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF56784 493 742 1.18E-60 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Pfam PF00689 Cation transporting ATPase, C-terminus 724 893 1.3E-37 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 339 345 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF81665 689 901 5.23E-114 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF81665 16 127 5.23E-114 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF81665 237 331 5.23E-114 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SMART SM00831 16 89 1.3E-32 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Pfam PF00690 Cation transporter/ATPase, N-terminus 18 83 4.1E-17 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 Pfam PF00122 E1-E2 ATPase 124 317 1.7E-50 T 28-03-2018 WM46_RS21675 43aa2f49119a5831cbafa20e97cb0f59 902 SUPERFAMILY SSF81660 344 542 5.45E-41 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS05190 82bb214b8745793c4df2d1da33fd9ed7 304 SUPERFAMILY SSF141986 139 288 4.71E-39 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain WM46_RS05190 82bb214b8745793c4df2d1da33fd9ed7 304 Pfam PF02016 LD-carboxypeptidase 6 284 2.9E-64 T 28-03-2018 IPR003507 Peptidase family S66 WM46_RS05190 82bb214b8745793c4df2d1da33fd9ed7 304 SUPERFAMILY SSF52317 4 160 5.04E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS05190 82bb214b8745793c4df2d1da33fd9ed7 304 Gene3D G3DSA:3.40.50.10740 1 144 1.4E-40 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain WM46_RS05190 82bb214b8745793c4df2d1da33fd9ed7 304 PIRSF PIRSF028757 1 300 5.3E-81 T 28-03-2018 IPR003507 Peptidase family S66 WM46_RS05190 82bb214b8745793c4df2d1da33fd9ed7 304 Gene3D G3DSA:3.50.30.60 145 299 1.2E-38 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain WM46_RS13175 657d0257c14c19dfdfe0a94d69f15323 293 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 4 292 50.313 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 WM46_RS13175 657d0257c14c19dfdfe0a94d69f15323 293 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 WM46_RS13175 657d0257c14c19dfdfe0a94d69f15323 293 Pfam PF13714 Phosphoenolpyruvate phosphomutase 10 250 2.1E-48 T 28-03-2018 WM46_RS13175 657d0257c14c19dfdfe0a94d69f15323 293 Gene3D G3DSA:3.20.20.60 2 293 6.1E-91 T 28-03-2018 WM46_RS13175 657d0257c14c19dfdfe0a94d69f15323 293 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 7 291 1.8E-135 T 28-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 WM46_RS13175 657d0257c14c19dfdfe0a94d69f15323 293 SUPERFAMILY SSF51621 4 288 2.65E-98 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS26085 ef7d144d1b18700b7925e22a566f3be1 1009 Pfam PF01526 Tn3 transposase DDE domain 596 988 2.1E-108 T 28-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 WM46_RS26085 ef7d144d1b18700b7925e22a566f3be1 1009 Pfam PF13700 Domain of unknown function (DUF4158) 11 172 1.1E-36 T 28-03-2018 IPR025296 Domain of unknown function DUF4158 WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 1 356 47.161 T 28-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 Gene3D G3DSA:3.40.50.300 134 355 0.0018 T 28-03-2018 WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 SUPERFAMILY SSF52821 91 152 1.7E-22 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 SUPERFAMILY SSF52821 8 63 1.7E-22 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 14 341 5.4E-102 T 28-03-2018 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 Pfam PF00581 Rhodanese-like domain 14 46 6.6E-6 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 SMART SM00450 1 131 3.5E-13 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS12245 101e506208be2701c64f4a5b8b8a31a2 356 Gene3D G3DSA:3.40.250.10 3 133 3.2E-20 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS22045 55015cdbdef2d7e4e6d4a939498fdb19 176 Gene3D G3DSA:2.60.40.1090 28 176 4.6E-29 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22045 55015cdbdef2d7e4e6d4a939498fdb19 176 Pfam PF00419 Fimbrial protein 30 176 4.9E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22045 55015cdbdef2d7e4e6d4a939498fdb19 176 SUPERFAMILY SSF49401 30 176 2.29E-33 T 28-03-2018 IPR008966 Adhesion domain WM46_RS16045 9ffd4fd7790c1caf1487e22fe0d9b437 245 SUPERFAMILY SSF69593 2 240 1.12E-60 T 28-03-2018 WM46_RS16045 9ffd4fd7790c1caf1487e22fe0d9b437 245 SMART SM00563 67 182 1.2E-39 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS16045 9ffd4fd7790c1caf1487e22fe0d9b437 245 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 180 5.0E-51 T 28-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 WM46_RS16045 9ffd4fd7790c1caf1487e22fe0d9b437 245 Gene3D G3DSA:3.40.1130.10 48 244 2.4E-39 T 28-03-2018 WM46_RS16045 9ffd4fd7790c1caf1487e22fe0d9b437 245 Pfam PF01553 Acyltransferase 54 180 4.6E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 PIRSF PIRSF001357 11 261 1.2E-76 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 17 238 1.2E-85 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 SUPERFAMILY SSF51569 12 252 3.56E-82 T 28-03-2018 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 Gene3D G3DSA:3.20.20.70 4 264 6.6E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 Pfam PF01791 DeoC/LacD family aldolase 17 251 1.0E-50 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 SMART SM01133 16 252 3.6E-80 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS24095 e4319f40badbd8b0b3e6f4c4df29f73e 265 Hamap MF_00592 Deoxyribose-phosphate aldolase [deoC]. 7 265 54.095 T 28-03-2018 IPR023649 Deoxyribose-phosphate aldolase type II GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 331 346 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 89 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 92 102 5.0E-69 T 28-03-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 Gene3D G3DSA:3.40.50.2300 26 176 3.8E-37 T 28-03-2018 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 Gene3D G3DSA:3.40.50.2300 177 352 6.8E-19 T 28-03-2018 WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 Pfam PF13458 Periplasmic binding protein 30 348 2.9E-56 T 28-03-2018 IPR028081 Leucine-binding protein domain WM46_RS18150 1f53140a65ffaf8959efaa7cd876a582 371 SUPERFAMILY SSF53822 29 362 1.14E-87 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS11440 4a681de54c3cef1c05b3069b3151d8ea 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 18.81 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 WM46_RS11440 4a681de54c3cef1c05b3069b3151d8ea 127 TIGRFAM TIGR00494 crcB: protein CrcB 6 121 8.0E-44 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 WM46_RS11440 4a681de54c3cef1c05b3069b3151d8ea 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 116 5.5E-24 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 WM46_RS09600 2d9a996701951a097446a58f7dedce82 105 Hamap MF_01194 Heat shock protein HspQ [hspQ]. 1 105 37.786 T 28-03-2018 IPR022866 Heat shock protein HspQ WM46_RS09600 2d9a996701951a097446a58f7dedce82 105 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 5 96 1.6E-19 T 28-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 WM46_RS09600 2d9a996701951a097446a58f7dedce82 105 SUPERFAMILY SSF141255 4 95 1.11E-29 T 28-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 WM46_RS09600 2d9a996701951a097446a58f7dedce82 105 SMART SM00992 3 102 1.8E-35 T 28-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 WM46_RS09600 2d9a996701951a097446a58f7dedce82 105 Gene3D G3DSA:2.30.30.390 1 105 1.4E-18 T 28-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 WM46_RS09600 2d9a996701951a097446a58f7dedce82 105 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 4 102 1.9E-35 T 28-03-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:3.90.1800.10 1267 1313 7.2E-12 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:3.90.1110.10 148 429 2.8E-67 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF00562 RNA polymerase Rpb2, domain 6 717 1264 1.2E-158 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF10385 RNA polymerase beta subunit external 1 domain 591 656 3.0E-27 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF04560 RNA polymerase Rpb2, domain 7 1266 1340 1.9E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1063 1075 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:3.90.1100.10 430 645 7.2E-80 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:3.90.1100.10 646 713 2.2E-14 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 SUPERFAMILY SSF64484 343 939 0.0 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 SUPERFAMILY SSF64484 11 226 0.0 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 SUPERFAMILY SSF64484 1039 1341 0.0 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF04565 RNA polymerase Rpb2, domain 3 513 580 1.5E-30 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:2.40.50.100 715 795 1.6E-27 T 28-03-2018 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 151 225 2.0E-7 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF04561 RNA polymerase Rpb2, domain 2 340 454 1.3E-15 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:2.40.270.10 1020 1242 6.7E-80 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Pfam PF04563 RNA polymerase beta subunit 26 500 2.3E-58 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1339 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Gene3D G3DSA:2.40.50.150 814 949 4.1E-29 T 28-03-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS21190 72b2a989c39820c18c8db03b70dcfa2a 1342 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1342 12.335 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS18050 0a2bcaf824a36c9ece63caf442c1b9fa 175 Pfam PF01202 Shikimate kinase 17 170 6.8E-12 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS18050 0a2bcaf824a36c9ece63caf442c1b9fa 175 Gene3D G3DSA:3.40.50.300 7 175 4.2E-28 T 28-03-2018 WM46_RS18050 0a2bcaf824a36c9ece63caf442c1b9fa 175 SUPERFAMILY SSF52540 4 172 3.15E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18050 0a2bcaf824a36c9ece63caf442c1b9fa 175 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 172 3.8E-72 T 28-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 WM46_RS16940 252f43084581506edb85ee9e56a29194 95 SUPERFAMILY SSF69754 1 95 8.11E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS16940 252f43084581506edb85ee9e56a29194 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 95 1.2E-36 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS16940 252f43084581506edb85ee9e56a29194 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 1.1E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS16940 252f43084581506edb85ee9e56a29194 95 Gene3D G3DSA:3.30.160.100 1 95 1.6E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS00970 5a319a6fd209c5935df80163aa1450fa 338 PIRSF PIRSF000428 1 327 3.3E-108 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS00970 5a319a6fd209c5935df80163aa1450fa 338 Pfam PF01515 Phosphate acetyl/butaryl transferase 2 320 1.0E-119 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS00970 5a319a6fd209c5935df80163aa1450fa 338 Gene3D G3DSA:3.40.50.2300 3 123 2.3E-4 T 28-03-2018 WM46_RS00970 5a319a6fd209c5935df80163aa1450fa 338 SUPERFAMILY SSF53659 2 321 2.01E-81 T 28-03-2018 WM46_RS00970 5a319a6fd209c5935df80163aa1450fa 338 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 17 319 1.0E-98 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS00970 5a319a6fd209c5935df80163aa1450fa 338 Gene3D G3DSA:3.40.50.10750 140 296 6.7E-57 T 28-03-2018 WM46_RS25890 98cfeeb2df4976cc29329d488f174381 337 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 98 2.1E-24 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS25890 98cfeeb2df4976cc29329d488f174381 337 Gene3D G3DSA:1.10.443.10 112 318 2.9E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS25890 98cfeeb2df4976cc29329d488f174381 337 Pfam PF00589 Phage integrase family 116 317 4.3E-64 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS25890 98cfeeb2df4976cc29329d488f174381 337 SUPERFAMILY SSF56349 16 316 1.41E-50 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS25890 98cfeeb2df4976cc29329d488f174381 337 TIGRFAM TIGR02249 integrase_gron: integron integrase 16 330 1.8E-153 T 28-03-2018 IPR011946 Integrase, integron-type GO:0003677|GO:0006310|GO:0015074 WM46_RS25890 98cfeeb2df4976cc29329d488f174381 337 Gene3D G3DSA:1.10.150.130 13 97 4.1E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 Gene3D G3DSA:3.40.190.10 93 181 3.3E-15 T 28-03-2018 WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 SUPERFAMILY SSF46785 6 86 5.57E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 Gene3D G3DSA:3.40.190.10 182 267 4.0E-8 T 28-03-2018 WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 SUPERFAMILY SSF53850 91 295 3.75E-22 T 28-03-2018 WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 Pfam PF03466 LysR substrate binding domain 89 274 1.3E-20 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 63 2.0E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 Gene3D G3DSA:1.10.10.10 2 92 4.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24580 3acec49f6ac340e37b5da0b474a21b69 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.1E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS18240 e4136bab8e2cf6e98fb40fcdc47f691b 353 Pfam PF00891 O-methyltransferase 179 332 2.5E-17 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 WM46_RS18240 e4136bab8e2cf6e98fb40fcdc47f691b 353 Gene3D G3DSA:1.10.10.10 7 95 2.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18240 e4136bab8e2cf6e98fb40fcdc47f691b 353 Gene3D G3DSA:3.40.50.150 96 353 9.0E-31 T 28-03-2018 WM46_RS18240 e4136bab8e2cf6e98fb40fcdc47f691b 353 SUPERFAMILY SSF53335 96 340 6.97E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 174 1.2E-51 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.828 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 3.2E-66 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 Gene3D G3DSA:1.10.520.20 2 106 6.1E-28 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 SUPERFAMILY SSF47928 3 105 5.23E-28 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 9.7E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 9.7E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 9.7E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 9.7E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19510 984dffef0fcb133da68afec731b73d13 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 9.7E-29 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 341 9.0E-10 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Pfam PF00817 impB/mucB/samB family 7 154 4.7E-49 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Gene3D G3DSA:1.10.150.20 171 242 4.2E-25 T 28-03-2018 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Gene3D G3DSA:3.30.1490.100 243 351 4.3E-29 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Gene3D G3DSA:3.30.70.270 114 170 6.7E-23 T 28-03-2018 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Gene3D G3DSA:3.30.70.270 41 113 1.5E-25 T 28-03-2018 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Hamap MF_01113 DNA polymerase IV [dinB]. 1 349 37.1 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 SUPERFAMILY SSF56672 1 234 5.52E-95 T 28-03-2018 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 SUPERFAMILY SSF100879 241 349 1.04E-26 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS13685 942b0bb4160197778cf002f751bea557 351 Pfam PF11798 IMS family HHH motif 166 197 2.4E-9 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 WM46_RS01700 d1d2bda593d777b97deee8d61b23290a 276 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 259 3.7E-44 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS01700 d1d2bda593d777b97deee8d61b23290a 276 Gene3D G3DSA:3.40.50.970 1 269 8.8E-65 T 28-03-2018 WM46_RS01700 d1d2bda593d777b97deee8d61b23290a 276 SUPERFAMILY SSF52518 4 268 1.08E-77 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS20635 a6581f1e5e5fb6ec3091e7708886e9f3 559 Pfam PF11658 Cellulose biosynthesis protein BcsG 24 554 7.1E-237 T 28-03-2018 IPR017744 Cellulose biosynthesis protein BcsG WM46_RS20635 a6581f1e5e5fb6ec3091e7708886e9f3 559 Gene3D G3DSA:3.40.720.10 200 505 5.0E-7 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS20635 a6581f1e5e5fb6ec3091e7708886e9f3 559 TIGRFAM TIGR03368 cellulose_yhjU: cellulose synthase operon protein YhjU 23 557 3.1E-243 T 28-03-2018 IPR017744 Cellulose biosynthesis protein BcsG WM46_RS18605 b923672f11a2c1f27a974184a7d4a916 104 Pfam PF05336 L-rhamnose mutarotase 3 103 2.2E-28 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 WM46_RS18605 b923672f11a2c1f27a974184a7d4a916 104 Gene3D G3DSA:3.30.70.100 2 101 2.8E-4 T 28-03-2018 WM46_RS18605 b923672f11a2c1f27a974184a7d4a916 104 TIGRFAM TIGR02625 YiiL_rotase: L-rhamnose mutarotase 3 104 6.2E-56 T 28-03-2018 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 WM46_RS18605 b923672f11a2c1f27a974184a7d4a916 104 Hamap MF_01663 L-rhamnose mutarotase [rhaM]. 1 104 31.84 T 28-03-2018 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 WM46_RS18605 b923672f11a2c1f27a974184a7d4a916 104 SUPERFAMILY SSF54909 1 103 8.35E-37 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS08990 0f742f62f5a6f329258dab51e45dd481 312 Hamap MF_01666 Glyoxylate/hydroxypyruvate reductase A [ghrA]. 1 312 63.92 T 28-03-2018 IPR023514 Glyoxylate/hydroxypyruvate reductase A GO:0016618|GO:0030267|GO:0055114 KEGG: 00260+1.1.1.81|KEGG: 00620+1.1.1.79|KEGG: 00630+1.1.1.79+1.1.1.81|MetaCyc: PWY-1622 WM46_RS08990 0f742f62f5a6f329258dab51e45dd481 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 216 232 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS08990 0f742f62f5a6f329258dab51e45dd481 312 Gene3D G3DSA:3.40.50.720 1 123 6.9E-12 T 28-03-2018 WM46_RS08990 0f742f62f5a6f329258dab51e45dd481 312 SUPERFAMILY SSF51735 98 278 1.92E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08990 0f742f62f5a6f329258dab51e45dd481 312 Gene3D G3DSA:3.40.50.720 124 278 8.5E-34 T 28-03-2018 WM46_RS08990 0f742f62f5a6f329258dab51e45dd481 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 277 1.8E-44 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 106 119 2.4E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 2.4E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 490 504 2.4E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 390 406 2.4E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 2.4E-37 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 709 745 2.9E-11 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 597 622 8.2E-6 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:3.30.65.10 578 645 2.1E-11 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:3.30.65.10 696 744 1.6E-9 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:3.30.65.10 745 807 2.3E-9 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:2.70.20.10 346 466 1.2E-38 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SUPERFAMILY SSF57783 809 864 2.55E-22 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SUPERFAMILY SSF57783 744 807 2.72E-19 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SMART SM00437 272 527 6.1E-127 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SMART SM00436 133 221 1.0E-48 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 309 323 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SMART SM00493 3 132 8.1E-35 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SUPERFAMILY SSF57783 704 743 2.89E-7 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:1.10.460.10 164 345 1.2E-45 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 635 4.3E-266 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:3.40.50.140 1 163 1.4E-51 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Pfam PF01131 DNA topoisomerase 157 565 3.4E-127 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 723 54.94 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:2.20.25.10 809 863 6.2E-30 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Pfam PF01751 Toprim domain 5 142 8.8E-34 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Pfam PF08272 Topoisomerase I zinc-ribbon-like 758 793 2.9E-12 T 28-03-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Pfam PF08272 Topoisomerase I zinc-ribbon-like 824 862 7.5E-21 T 28-03-2018 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 Gene3D G3DSA:1.10.460.10 467 577 3.3E-30 T 28-03-2018 WM46_RS05895 cfb15c2fadb5c6c2f6f9dca591de8d83 865 SUPERFAMILY SSF56712 3 609 2.75E-206 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 Gene3D G3DSA:3.40.640.10 139 381 1.3E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 8.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 SUPERFAMILY SSF46785 7 81 1.77E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 Gene3D G3DSA:1.10.10.10 2 78 1.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 Pfam PF00155 Aminotransferase class I and II 133 401 4.2E-16 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 SUPERFAMILY SSF53383 113 487 5.68E-65 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 SMART SM00345 18 77 3.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS02335 4ea88c3bb6b7b94ffcab02678db2e928 493 Gene3D G3DSA:3.90.1150.10 382 491 2.2E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 SUPERFAMILY SSF55874 1 200 5.63E-57 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 Pfam PF08676 MutL C terminal dimerisation domain 440 568 7.8E-25 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 SUPERFAMILY SSF118116 439 618 6.67E-44 T 28-03-2018 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 SUPERFAMILY SSF54211 191 331 8.34E-35 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 SMART SM00853 443 578 6.4E-17 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 330 5.3E-35 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 SMART SM01340 212 331 8.3E-54 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 Gene3D G3DSA:3.30.230.10 217 330 1.1E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 617 25.567 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 311 6.7E-106 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 Gene3D G3DSA:3.30.565.10 1 216 5.2E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS22875 2c548ad5ae57d53b989f65f2b84cab89 620 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 122 1.0E-12 T 28-03-2018 WM46_RS24740 119024198ba6d4579814fd9c35bf03b0 267 Pfam PF00486 Transcriptional regulatory protein, C terminal 39 109 1.7E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS24740 119024198ba6d4579814fd9c35bf03b0 267 SUPERFAMILY SSF46894 32 111 3.97E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS24740 119024198ba6d4579814fd9c35bf03b0 267 SMART SM00862 35 112 2.8E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS24740 119024198ba6d4579814fd9c35bf03b0 267 Gene3D G3DSA:1.10.10.10 7 119 4.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 Pfam PF00365 Phosphofructokinase 2 280 2.6E-59 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 SUPERFAMILY SSF53784 1 323 4.45E-69 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PIRSF PIRSF000532 1 326 8.3E-64 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 Gene3D G3DSA:3.40.50.450 1 211 3.7E-49 T 28-03-2018 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 134 152 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 155 171 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 244 266 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 89 105 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 208 220 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 116 133 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18660 3f82176df1c6b9e89bb6fb4443dbbccc 326 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 173 190 6.0E-33 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 50 126 1.2E-19 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 Gene3D G3DSA:1.10.286.20 3 43 3.4E-12 T 28-03-2018 WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 SUPERFAMILY SSF54534 49 127 5.89E-18 T 28-03-2018 WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 Hamap MF_00954 Regulator of nucleoside diphosphate kinase [rnk]. 1 136 43.353 T 28-03-2018 IPR028625 Regulator of nucleoside diphosphate kinase GO:0065007|GO:0070063 WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 PIRSF PIRSF006092 30 128 1.7E-22 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 Pfam PF14760 Rnk N-terminus 4 42 3.0E-11 T 28-03-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain WM46_RS11525 29294d483761883f2a7b280e898cb1f2 136 Gene3D G3DSA:3.10.50.30 45 136 1.0E-22 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 Gene3D G3DSA:3.40.640.10 1 233 1.3E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 Gene3D G3DSA:3.90.1150.10 234 404 4.8E-53 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 SUPERFAMILY SSF53383 5 390 1.34E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 55.858 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 3.5E-234 T 28-03-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 PIRSF PIRSF005572 2 384 9.9E-144 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site WM46_RS00620 9abd352d12881f7f0eee786f091f94df 404 Pfam PF00266 Aminotransferase class-V 5 368 1.4E-88 T 28-03-2018 IPR000192 Aminotransferase class V domain WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 Gene3D G3DSA:3.10.310.10 1 124 3.8E-48 T 28-03-2018 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 SUPERFAMILY SSF54506 2 273 2.96E-56 T 28-03-2018 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 274 39.889 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 273 3.6E-104 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 Gene3D G3DSA:3.10.310.10 125 261 1.4E-51 T 28-03-2018 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 Pfam PF01678 Diaminopimelate epimerase 3 123 1.3E-34 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM46_RS19115 cad2d292f9eed23344f1ccdf62cd9b58 274 Pfam PF01678 Diaminopimelate epimerase 152 266 5.3E-34 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 SUPERFAMILY SSF46894 132 234 2.07E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 Pfam PF00072 Response regulator receiver domain 7 117 1.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 2.2E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 Gene3D G3DSA:1.10.10.10 126 239 7.0E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 SMART SM00448 5 116 8.6E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 Gene3D G3DSA:3.40.50.2300 2 125 2.0E-38 T 28-03-2018 WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 SUPERFAMILY SSF52172 3 126 8.4E-42 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS17855 d8521a76d5088ea0467c0daab9e28465 239 SMART SM00862 156 232 1.7E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 PIRSF PIRSF002158 12 273 3.2E-101 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 SMART SM01383 42 118 1.9E-48 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 SUPERFAMILY SSF50249 3 125 5.14E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 272 3.6E-132 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 SMART SM01382 124 251 7.5E-90 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.144 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 Gene3D G3DSA:4.10.950.10 197 272 3.3E-35 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 7.9E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 SUPERFAMILY SSF50104 126 269 1.44E-59 T 28-03-2018 IPR008991 Translation protein SH3-like domain WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 Gene3D G3DSA:2.30.30.30 119 195 1.3E-31 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 249 9.7E-56 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 WM46_RS17530 b8dda3d5223018c567ea5f3ca22e9fbc 273 Gene3D G3DSA:2.40.50.140 1 114 3.6E-48 T 28-03-2018 WM46_RS24970 4fc64ea71e47b39ac5b7c1ed052a3637 75 Pfam PF06004 Bacterial protein of unknown function (DUF903) 24 72 1.4E-24 T 28-03-2018 IPR010305 Protein of unknown function DUF903 WM46_RS24970 4fc64ea71e47b39ac5b7c1ed052a3637 75 SUPERFAMILY SSF50182 23 73 6.0E-19 T 28-03-2018 IPR010920 LSM domain WM46_RS24970 4fc64ea71e47b39ac5b7c1ed052a3637 75 Gene3D G3DSA:2.30.30.100 22 73 6.5E-32 T 28-03-2018 WM46_RS22925 7ce58db03dcd1c81354b7ea9924be888 334 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 9 329 9.5E-96 T 28-03-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 WM46_RS22925 7ce58db03dcd1c81354b7ea9924be888 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 319 7.1E-58 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS22925 7ce58db03dcd1c81354b7ea9924be888 334 Gene3D G3DSA:3.40.50.1100 145 334 1.7E-31 T 28-03-2018 WM46_RS22925 7ce58db03dcd1c81354b7ea9924be888 334 SUPERFAMILY SSF53686 4 332 3.57E-88 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS22925 7ce58db03dcd1c81354b7ea9924be888 334 Gene3D G3DSA:3.40.50.1100 48 144 1.5E-29 T 28-03-2018 WM46_RS22925 7ce58db03dcd1c81354b7ea9924be888 334 PIRSF PIRSF006278 1 334 2.9E-102 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase WM46_RS18275 e96041f5b1ebda393f01066c66e88682 117 SUPERFAMILY SSF54637 7 103 3.03E-16 T 28-03-2018 IPR029069 HotDog domain WM46_RS18275 e96041f5b1ebda393f01066c66e88682 117 Pfam PF07977 FabA-like domain 19 88 6.3E-6 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS18275 e96041f5b1ebda393f01066c66e88682 117 Gene3D G3DSA:3.10.129.10 4 117 1.3E-22 T 28-03-2018 WM46_RS18275 e96041f5b1ebda393f01066c66e88682 117 PIRSF PIRSF030962 1 117 3.3E-56 T 28-03-2018 IPR016962 Dehydrase, ECs4332, predicted KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS16865 2afad0075933435b8cc989c336145dc9 95 Gene3D G3DSA:1.10.260.40 1 73 5.2E-12 T 28-03-2018 WM46_RS16865 2afad0075933435b8cc989c336145dc9 95 Pfam PF13693 Winged helix-turn-helix DNA-binding 7 81 9.3E-35 T 28-03-2018 WM46_RS16865 2afad0075933435b8cc989c336145dc9 95 SUPERFAMILY SSF47413 3 71 9.56E-29 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS19810 c0dd75a012b2948ac937e8889cbf5030 96 Pfam PF13710 ACT domain 18 78 2.4E-9 T 28-03-2018 WM46_RS19810 c0dd75a012b2948ac937e8889cbf5030 96 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 15 78 1.0E-15 T 28-03-2018 WM46_RS19810 c0dd75a012b2948ac937e8889cbf5030 96 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 9 82 3.3E-16 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 WM46_RS19810 c0dd75a012b2948ac937e8889cbf5030 96 Gene3D G3DSA:3.30.70.260 1 96 2.6E-20 T 28-03-2018 WM46_RS19810 c0dd75a012b2948ac937e8889cbf5030 96 SUPERFAMILY SSF55021 9 80 3.31E-16 T 28-03-2018 WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 Gene3D G3DSA:3.30.230.20 1 128 3.7E-49 T 28-03-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 276 1.3E-109 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 301 1.3E-163 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 SUPERFAMILY SSF54211 134 278 3.11E-54 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 280 46.26 T 28-03-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 SUPERFAMILY SSF54211 3 124 4.17E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS14350 2c79edb104580de159adc12790fdd79f 305 Gene3D G3DSA:3.30.1700.10 129 299 5.1E-70 T 28-03-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 131 186 7.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 SMART SM00388 129 194 2.5E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 Gene3D G3DSA:3.30.565.10 193 349 3.0E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 328 1.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 295 1.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 346 1.7E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 Gene3D G3DSA:1.10.287.130 118 187 2.0E-13 T 28-03-2018 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 234 347 2.6E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 SMART SM00091 7 75 1.6E-7 T 28-03-2018 IPR000014 PAS domain WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 SUPERFAMILY SSF47384 121 186 3.53E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 Pfam PF00989 PAS fold 11 98 2.9E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 Gene3D G3DSA:3.30.450.20 9 108 9.1E-11 T 28-03-2018 WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 SUPERFAMILY SSF55785 11 102 3.54E-6 T 28-03-2018 IPR000014 PAS domain WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 SMART SM00387 233 349 7.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18840 4d8c3f048e25c0a7938dc417e4040647 349 SUPERFAMILY SSF55874 198 346 2.49E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS17990 a199fdf583a059ac5fc12c423708026a 443 Gene3D G3DSA:1.20.1250.20 226 426 1.1E-23 T 28-03-2018 WM46_RS17990 a199fdf583a059ac5fc12c423708026a 443 Pfam PF07690 Major Facilitator Superfamily 22 380 2.1E-56 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS17990 a199fdf583a059ac5fc12c423708026a 443 SUPERFAMILY SSF103473 5 417 2.22E-85 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS17990 a199fdf583a059ac5fc12c423708026a 443 Gene3D G3DSA:1.20.1250.20 6 210 1.6E-37 T 28-03-2018 WM46_RS18290 64aca9d2eb86bfcb5b75ebceff4f2f45 201 SUPERFAMILY SSF89392 20 187 4.32E-23 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX WM46_RS18290 64aca9d2eb86bfcb5b75ebceff4f2f45 201 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 187 2.2E-10 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like WM46_RS18290 64aca9d2eb86bfcb5b75ebceff4f2f45 201 Gene3D G3DSA:2.50.20.10 18 194 1.3E-18 T 28-03-2018 WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 6 441 2.2E-144 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 Gene3D G3DSA:3.40.50.300 165 449 7.8E-60 T 28-03-2018 WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 Pfam PF00772 DnaB-like helicase N terminal domain 6 107 2.3E-31 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 SUPERFAMILY SSF48024 6 115 7.45E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 Pfam PF03796 DnaB-like helicase C terminal domain 182 438 8.4E-95 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 Gene3D G3DSA:1.10.860.10 1 147 1.0E-38 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 SUPERFAMILY SSF52540 180 432 1.34E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15690 1b8d91327db4c0aea485d7b24ac7103e 456 SMART SM00382 199 399 9.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS04985 cc810bb98b55610ca0032084c12a6c03 192 Pfam PF00293 NUDIX domain 30 143 9.2E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS04985 cc810bb98b55610ca0032084c12a6c03 192 Gene3D G3DSA:3.90.79.10 4 189 7.5E-42 T 28-03-2018 WM46_RS04985 cc810bb98b55610ca0032084c12a6c03 192 Hamap MF_01592 Uncharacterized Nudix hydrolase NudL [nudL]. 1 190 49.989 T 28-03-2018 IPR023735 Uncharacterised nudix hydrolase NudL GO:0016818 WM46_RS04985 cc810bb98b55610ca0032084c12a6c03 192 ProSitePatterns PS01293 Nudix CoA signature. 47 67 - T 28-03-2018 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 Reactome: R-HSA-390918 WM46_RS04985 cc810bb98b55610ca0032084c12a6c03 192 SUPERFAMILY SSF55811 8 181 2.57E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS12435 da26eb0f139dcca1954293ed43e8f18d 397 Gene3D G3DSA:1.20.1600.10 29 391 1.3E-35 T 28-03-2018 WM46_RS12435 da26eb0f139dcca1954293ed43e8f18d 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 293 6.4E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS12435 da26eb0f139dcca1954293ed43e8f18d 397 SUPERFAMILY SSF111369 52 300 5.1E-89 T 28-03-2018 WM46_RS12435 da26eb0f139dcca1954293ed43e8f18d 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 375 7.1E-85 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS12435 da26eb0f139dcca1954293ed43e8f18d 397 Pfam PF00529 HlyD membrane-fusion protein of T1SS 118 360 2.7E-10 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS17615 627621bc1a34b288526853a5a10ff76f 274 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 33 152 5.2E-36 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM46_RS17615 627621bc1a34b288526853a5a10ff76f 274 Gene3D G3DSA:1.10.287.460 26 133 1.2E-28 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM46_RS17615 627621bc1a34b288526853a5a10ff76f 274 Gene3D G3DSA:3.10.50.40 134 250 6.4E-43 T 28-03-2018 WM46_RS17615 627621bc1a34b288526853a5a10ff76f 274 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 246 3.6E-28 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM46_RS17615 627621bc1a34b288526853a5a10ff76f 274 SUPERFAMILY SSF54534 41 249 1.3E-65 T 28-03-2018 WM46_RS04115 fd86e132bc6184e8cb48b859584c6067 297 Pfam PF01618 MotA/TolQ/ExbB proton channel family 140 239 2.6E-11 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 WM46_RS04115 fd86e132bc6184e8cb48b859584c6067 297 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site WM46_RS04115 fd86e132bc6184e8cb48b859584c6067 297 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 281 4.2E-117 T 28-03-2018 IPR022522 Flagellar motor stator, MotA WM46_RS25910 736c010e8c5c56df94bcdcc42ba1c38c 254 SUPERFAMILY SSF53098 72 192 1.29E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS25910 736c010e8c5c56df94bcdcc42ba1c38c 254 Pfam PF13610 DDE domain 73 211 3.9E-50 T 28-03-2018 IPR032874 DDE domain WM46_RS25910 736c010e8c5c56df94bcdcc42ba1c38c 254 Gene3D G3DSA:3.30.420.10 62 209 2.6E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS21750 5224685581efa8d885deb1ba1469ecd4 549 TIGRFAM TIGR02711 symport_actP: cation/acetate symporter ActP 2 549 0.0 T 28-03-2018 IPR014083 Cation/acetate symporter ActP GO:0005887|GO:0015123|GO:0043879 WM46_RS21750 5224685581efa8d885deb1ba1469ecd4 549 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 450 470 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS21750 5224685581efa8d885deb1ba1469ecd4 549 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 63 466 5.3E-63 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS21750 5224685581efa8d885deb1ba1469ecd4 549 Hamap MF_01426 Cation/acetate symporter ActP [actP]. 1 549 59.599 T 28-03-2018 IPR014083 Cation/acetate symporter ActP GO:0005887|GO:0015123|GO:0043879 WM46_RS21750 5224685581efa8d885deb1ba1469ecd4 549 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 178 203 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS21750 5224685581efa8d885deb1ba1469ecd4 549 Pfam PF00474 Sodium:solute symporter family 63 468 7.6E-138 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 Gene3D G3DSA:3.30.420.40 73 209 7.3E-19 T 28-03-2018 WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 Pfam PF01047 MarR family 25 63 1.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 Gene3D G3DSA:1.10.10.10 13 72 1.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 ProSitePatterns PS01125 ROK family signature. 220 247 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 SUPERFAMILY SSF46785 14 79 2.27E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 Pfam PF00480 ROK family 89 392 1.7E-98 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 Gene3D G3DSA:3.30.420.40 210 402 6.8E-47 T 28-03-2018 WM46_RS11230 aa746ca7dac14a6a1e9d03edf1e78dcd 406 SUPERFAMILY SSF53067 88 394 3.78E-53 T 28-03-2018 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 239 4.8E-107 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 SUPERFAMILY SSF102114 23 216 2.16E-24 T 28-03-2018 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 Pfam PF04055 Radical SAM superfamily 24 178 2.4E-31 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 PIRSF PIRSF000371 44 246 5.2E-48 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 PIRSF PIRSF000371 1 47 3.7E-10 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 Pfam PF13353 4Fe-4S single cluster domain 16 141 2.5E-18 T 28-03-2018 WM46_RS09895 3f826cd203be5401e3ce4a4a43b66dec 246 Gene3D G3DSA:3.80.30.10 68 246 4.6E-40 T 28-03-2018 WM46_RS15860 ddaf99fc3622494f85700c6fd996fe48 147 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 54 147 1.0E-36 T 28-03-2018 IPR004914 Antirestriction protein WM46_RS15860 ddaf99fc3622494f85700c6fd996fe48 147 Pfam PF03230 Antirestriction protein 56 147 2.2E-37 T 28-03-2018 IPR004914 Antirestriction protein WM46_RS25020 ac0c17931b0c2b24459ec79b42f33a46 316 Gene3D G3DSA:3.40.50.2300 132 312 2.9E-40 T 28-03-2018 WM46_RS25020 ac0c17931b0c2b24459ec79b42f33a46 316 Pfam PF13407 Periplasmic binding protein domain 29 283 7.1E-65 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS25020 ac0c17931b0c2b24459ec79b42f33a46 316 Gene3D G3DSA:3.40.50.2300 20 131 2.1E-18 T 28-03-2018 WM46_RS25020 ac0c17931b0c2b24459ec79b42f33a46 316 SUPERFAMILY SSF53822 27 308 1.14E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 Hamap MF_00740 Phosphopentomutase [deoB]. 1 407 55.288 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 Gene3D G3DSA:3.40.720.10 277 406 9.4E-11 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 SUPERFAMILY SSF53649 1 114 5.0E-69 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 SUPERFAMILY SSF53649 236 407 5.0E-69 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 Gene3D G3DSA:3.30.70.1250 126 235 1.6E-51 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 PIRSF PIRSF001491 1 407 4.9E-163 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 SUPERFAMILY SSF143856 117 235 2.75E-50 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 Pfam PF01676 Metalloenzyme superfamily 2 398 2.3E-44 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 Gene3D G3DSA:3.40.720.10 1 125 7.0E-20 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS24105 a6f8ba11af7e77d48eef49ccd800ae50 407 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 404 6.0E-201 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SMART SM00065 26 174 2.0E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SMART SM00065 202 354 7.6E-23 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SUPERFAMILY SSF52540 380 617 3.03E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Gene3D G3DSA:3.30.450.40 10 170 2.2E-15 T 28-03-2018 IPR029016 GAF domain-like WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Pfam PF01590 GAF domain 202 344 5.2E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Pfam PF02954 Bacterial regulatory protein, Fis family 645 684 1.5E-5 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Gene3D G3DSA:3.40.50.300 380 553 7.7E-30 T 28-03-2018 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SUPERFAMILY SSF46689 593 687 9.86E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Pfam PF00158 Sigma-54 interaction domain 381 548 4.1E-70 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Gene3D G3DSA:1.10.8.60 554 610 1.7E-21 T 28-03-2018 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SMART SM00382 401 545 2.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25355 6012239f594370d9276bbd908acef56b 692 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 405 418 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SUPERFAMILY SSF55781 26 168 2.4E-12 T 28-03-2018 IPR029016 GAF domain-like WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Gene3D G3DSA:1.10.10.60 611 688 1.8E-10 T 28-03-2018 WM46_RS25355 6012239f594370d9276bbd908acef56b 692 SUPERFAMILY SSF55781 184 360 2.18E-22 T 28-03-2018 IPR029016 GAF domain-like WM46_RS25355 6012239f594370d9276bbd908acef56b 692 Gene3D G3DSA:3.30.450.40 176 379 5.9E-25 T 28-03-2018 IPR029016 GAF domain-like WM46_RS25355 6012239f594370d9276bbd908acef56b 692 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 594 603 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Pfam PF00990 Diguanylate cyclase, GGDEF domain 378 527 4.0E-24 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Gene3D G3DSA:3.30.450.20 129 387 5.0E-26 T 28-03-2018 WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Pfam PF00563 EAL domain 549 783 8.1E-69 T 28-03-2018 IPR001633 EAL domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Pfam PF13426 PAS domain 149 250 7.9E-16 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Pfam PF13426 PAS domain 25 124 3.7E-11 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 PIRSF PIRSF005925 311 799 1.7E-151 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 PIRSF PIRSF005925 125 313 4.0E-24 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 PIRSF PIRSF005925 4 135 1.7E-20 T 28-03-2018 IPR012226 Diguanylate cyclase/phosphodiesterase WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SUPERFAMILY SSF141868 549 795 4.32E-84 T 28-03-2018 IPR001633 EAL domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SUPERFAMILY SSF55073 381 534 1.18E-27 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SMART SM00091 12 78 2.6E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SMART SM00091 136 203 2.9E-6 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SMART SM00267 365 532 1.8E-36 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SMART SM00086 209 251 1.5E-6 T 28-03-2018 IPR001610 PAC motif WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SMART SM00086 88 128 2.6 T 28-03-2018 IPR001610 PAC motif WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SUPERFAMILY SSF55785 26 133 1.92E-19 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Gene3D G3DSA:3.20.20.450 541 798 1.1E-94 T 28-03-2018 IPR001633 EAL domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 18 131 6.1E-20 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 132 256 7.2E-20 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 529 1.6E-17 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Gene3D G3DSA:3.30.70.270 388 540 2.5E-35 T 28-03-2018 WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SUPERFAMILY SSF55785 128 249 4.36E-19 T 28-03-2018 IPR000014 PAS domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 SMART SM00052 542 788 3.3E-117 T 28-03-2018 IPR001633 EAL domain WM46_RS06880 2d31cc193931cf4ccfab20e283b3d78a 801 Gene3D G3DSA:3.30.450.20 15 126 4.3E-16 T 28-03-2018 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 Gene3D G3DSA:3.90.1150.10 1 69 1.8E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 PRINTS PR00799 Aspartate aminotransferase signature 274 299 8.1E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 PRINTS PR00799 Aspartate aminotransferase signature 176 195 8.1E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 PRINTS PR00799 Aspartate aminotransferase signature 342 360 8.1E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 PRINTS PR00799 Aspartate aminotransferase signature 207 219 8.1E-38 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 Gene3D G3DSA:3.40.640.10 70 253 1.0E-6 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 Gene3D G3DSA:3.90.1150.10 254 397 1.3E-48 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 SUPERFAMILY SSF53383 2 396 1.54E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS21645 6e798eff5e45e2746c1cf3ca8e86639e 397 Pfam PF00155 Aminotransferase class I and II 27 392 4.7E-85 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Gene3D G3DSA:1.10.8.60 766 857 2.7E-24 T 28-03-2018 WM46_RS00280 585db0564e529010f641b9d52313250f 857 SMART SM00382 198 343 5.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00280 585db0564e529010f641b9d52313250f 857 SMART SM00382 597 752 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00280 585db0564e529010f641b9d52313250f 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 854 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 337 1.3E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 845 3.7E-28 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS00280 585db0564e529010f641b9d52313250f 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 1.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 1.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 1.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Gene3D G3DSA:1.10.1780.10 1 151 1.2E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Gene3D G3DSA:3.40.50.300 157 342 1.7E-25 T 28-03-2018 WM46_RS00280 585db0564e529010f641b9d52313250f 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 WM46_RS00280 585db0564e529010f641b9d52313250f 857 SUPERFAMILY SSF81923 4 156 4.32E-43 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS00280 585db0564e529010f641b9d52313250f 857 SMART SM01086 766 855 1.1E-37 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS00280 585db0564e529010f641b9d52313250f 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Gene3D G3DSA:3.40.50.300 552 765 1.0E-54 T 28-03-2018 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 760 2.0E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.3E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS00280 585db0564e529010f641b9d52313250f 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 9.3E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS00280 585db0564e529010f641b9d52313250f 857 SUPERFAMILY SSF52540 159 545 1.85E-99 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00280 585db0564e529010f641b9d52313250f 857 Gene3D G3DSA:1.10.8.60 343 547 1.4E-44 T 28-03-2018 WM46_RS00280 585db0564e529010f641b9d52313250f 857 SUPERFAMILY SSF52540 546 853 1.74E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00380 8c75e78aa218ca374887c6d20b512d74 216 PIRSF PIRSF016938 1 205 1.2E-36 T 28-03-2018 IPR026279 Sigma-E factor negative regulatory protein RseA GO:0006950|GO:0016989 WM46_RS00380 8c75e78aa218ca374887c6d20b512d74 216 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 132 186 6.0E-26 T 28-03-2018 IPR005573 Anti sigma-E protein RseA, C-terminal WM46_RS00380 8c75e78aa218ca374887c6d20b512d74 216 SUPERFAMILY SSF89069 1 66 5.23E-23 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 WM46_RS00380 8c75e78aa218ca374887c6d20b512d74 216 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 1 87 2.2E-37 T 28-03-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 WM46_RS01540 c2fbe8b968b751b6e91ddaab67a5da1d 86 Pfam PF13693 Winged helix-turn-helix DNA-binding 7 71 6.7E-29 T 28-03-2018 WM46_RS01540 c2fbe8b968b751b6e91ddaab67a5da1d 86 Gene3D G3DSA:1.10.260.40 1 73 2.7E-17 T 28-03-2018 WM46_RS01540 c2fbe8b968b751b6e91ddaab67a5da1d 86 SMART SM00530 12 64 0.0042 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS01540 c2fbe8b968b751b6e91ddaab67a5da1d 86 SUPERFAMILY SSF47413 2 72 1.16E-27 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS25525 506dc86ed179a6fd5df83efe3e625932 166 Gene3D G3DSA:1.10.10.10 70 114 5.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25525 506dc86ed179a6fd5df83efe3e625932 166 Hamap MF_01114 Regulatory protein RecX [recX]. 10 166 13.043 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 WM46_RS25525 506dc86ed179a6fd5df83efe3e625932 166 Gene3D G3DSA:1.10.10.10 12 69 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25525 506dc86ed179a6fd5df83efe3e625932 166 Gene3D G3DSA:1.10.10.10 116 166 8.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25525 506dc86ed179a6fd5df83efe3e625932 166 Pfam PF02631 RecX family 48 162 1.2E-29 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 WM46_RS22260 49ce29cb0d359b0e9bf6bd33458589a8 158 Pfam PF01464 Transglycosylase SLT domain 19 141 6.7E-20 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS22260 49ce29cb0d359b0e9bf6bd33458589a8 158 Gene3D G3DSA:1.10.530.10 18 153 4.1E-14 T 28-03-2018 WM46_RS22260 49ce29cb0d359b0e9bf6bd33458589a8 158 SUPERFAMILY SSF53955 13 149 1.04E-28 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS23075 b7623d9e4cc7622bb909818c2a2bf5ba 68 Pfam PF06526 Protein of unknown function (DUF1107) 1 63 2.1E-30 T 28-03-2018 IPR009491 Protein of unknown function DUF1107 WM46_RS23075 b7623d9e4cc7622bb909818c2a2bf5ba 68 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 63 2.0E-29 T 28-03-2018 IPR009491 Protein of unknown function DUF1107 WM46_RS23075 b7623d9e4cc7622bb909818c2a2bf5ba 68 Gene3D G3DSA:3.30.1910.10 1 62 8.9E-32 T 28-03-2018 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.2E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 Gene3D G3DSA:1.10.260.40 2 54 8.3E-24 T 28-03-2018 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 Gene3D G3DSA:3.40.50.2300 176 313 5.1E-43 T 28-03-2018 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 SUPERFAMILY SSF53822 61 333 2.86E-73 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.3E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 SUPERFAMILY SSF47413 1 59 6.14E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 Pfam PF13377 Periplasmic binding protein-like domain 169 329 9.8E-33 T 28-03-2018 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 Gene3D G3DSA:3.40.50.2300 55 175 5.4E-30 T 28-03-2018 WM46_RS24800 2beca6772dc3b0c303f92a82c991106d 337 SMART SM00354 1 71 2.4E-32 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23730 52fffb6f57471f2eba23d135c71a5d70 305 Pfam PF00682 HMGL-like 5 277 2.5E-46 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 WM46_RS23730 52fffb6f57471f2eba23d135c71a5d70 305 Gene3D G3DSA:3.20.20.70 1 294 2.6E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS23730 52fffb6f57471f2eba23d135c71a5d70 305 SUPERFAMILY SSF51569 2 279 9.96E-63 T 28-03-2018 WM46_RS00350 2da9206820adc280578c45904c13f03a 127 Hamap MF_00806 Autonomous glycyl radical cofactor [grcA]. 1 127 43.377 T 28-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA WM46_RS00350 2da9206820adc280578c45904c13f03a 127 TIGRFAM TIGR04365 spare_glycyl: autonomous glycyl radical cofactor GrcA 2 127 5.4E-70 T 28-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA WM46_RS00350 2da9206820adc280578c45904c13f03a 127 Pfam PF01228 Glycine radical 16 108 1.0E-22 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 WM46_RS00350 2da9206820adc280578c45904c13f03a 127 PIRSF PIRSF000378 2 127 4.9E-56 T 28-03-2018 IPR011140 Autonomous glycyl radical cofactor GrcA WM46_RS00350 2da9206820adc280578c45904c13f03a 127 SUPERFAMILY SSF51998 64 126 3.07E-24 T 28-03-2018 WM46_RS00350 2da9206820adc280578c45904c13f03a 127 Gene3D G3DSA:3.20.70.20 59 127 6.1E-30 T 28-03-2018 WM46_RS00350 2da9206820adc280578c45904c13f03a 127 ProSitePatterns PS00850 Glycine radical domain signature. 97 105 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site WM46_RS22900 118b6a7be401d9552278f8d264d118f9 334 SUPERFAMILY SSF117892 196 233 1.28E-7 T 28-03-2018 IPR001107 Band 7 domain WM46_RS22900 118b6a7be401d9552278f8d264d118f9 334 Pfam PF01145 SPFH domain / Band 7 family 22 243 2.8E-33 T 28-03-2018 IPR001107 Band 7 domain WM46_RS22900 118b6a7be401d9552278f8d264d118f9 334 TIGRFAM TIGR01932 hflC: HflC protein 1 327 1.2E-142 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 WM46_RS22900 118b6a7be401d9552278f8d264d118f9 334 SUPERFAMILY SSF117892 56 157 2.48E-16 T 28-03-2018 IPR001107 Band 7 domain WM46_RS22900 118b6a7be401d9552278f8d264d118f9 334 SMART SM00244 18 227 2.7E-44 T 28-03-2018 IPR001107 Band 7 domain WM46_RS22900 118b6a7be401d9552278f8d264d118f9 334 PIRSF PIRSF005651 1 334 2.9E-108 T 28-03-2018 IPR010200 HflC GO:0016021|GO:0052547 WM46_RS25700 aec12e11d916468060940fc9b4b1916e 56 Pfam PF01679 Proteolipid membrane potential modulator 3 48 2.3E-17 T 28-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 WM46_RS25700 aec12e11d916468060940fc9b4b1916e 56 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 7 22 - T 28-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 SMART SM00998 364 443 8.5E-29 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 SUPERFAMILY SSF48557 10 446 1.57E-122 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 Gene3D G3DSA:1.10.40.30 376 443 2.6E-23 T 28-03-2018 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 10 349 5.3E-108 T 28-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 Pfam PF00206 Lyase 17 297 1.9E-52 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 2.2E-25 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.2E-25 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 2.2E-25 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 2.2E-25 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 1.8E-11 T 28-03-2018 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00145 Argininosuccinate lyase family signature 100 122 1.8E-11 T 28-03-2018 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 1.8E-11 T 28-03-2018 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 1.8E-11 T 28-03-2018 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 Pfam PF10397 Adenylosuccinate lyase C-terminus 365 442 1.0E-19 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 Gene3D G3DSA:1.20.200.10 106 375 8.7E-83 T 28-03-2018 WM46_RS10470 ac1f57b80ba10449ecb494ea004a856a 450 Gene3D G3DSA:1.10.275.10 4 105 9.0E-21 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 SUPERFAMILY SSF111304 2 199 1.57E-72 T 28-03-2018 IPR023627 Recombination protein RecR WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 Pfam PF13662 Toprim domain 82 172 7.3E-24 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 TIGRFAM TIGR00615 recR: recombination protein RecR 2 197 7.4E-84 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 Gene3D G3DSA:1.10.150.20 5 38 0.4 T 28-03-2018 WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 104.317 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 SMART SM00493 81 166 1.7E-20 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 Gene3D G3DSA:3.40.1360.10 78 171 3.8E-35 T 28-03-2018 WM46_RS12380 ae4e8814fbab8ee1ee6efb9af27e4286 201 Pfam PF02132 RecR protein 41 77 2.1E-15 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger WM46_RS23760 32dfaf33f2d87f43d9abb0603052fa43 399 Gene3D G3DSA:1.20.1250.20 206 389 1.2E-13 T 28-03-2018 WM46_RS23760 32dfaf33f2d87f43d9abb0603052fa43 399 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 23 379 5.3E-124 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB WM46_RS23760 32dfaf33f2d87f43d9abb0603052fa43 399 SUPERFAMILY SSF103473 10 389 2.88E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS23760 32dfaf33f2d87f43d9abb0603052fa43 399 Gene3D G3DSA:1.20.1250.20 10 205 3.2E-10 T 28-03-2018 WM46_RS01055 55e99548e4cbdfda20f4e652b2a674e2 191 ProDom PD105195 LIPOPROTEIN YFEY MEMBRANE OUTER PRECURSOR SIGNAL ESCHERICHIA ECS3303 EXPORTED Y1456 1 191 3.0E-94 T 28-03-2018 IPR010938 Protein of unknown function DUF1131 WM46_RS01055 55e99548e4cbdfda20f4e652b2a674e2 191 Gene3D G3DSA:2.60.460.10 31 190 9.9E-69 T 28-03-2018 WM46_RS01055 55e99548e4cbdfda20f4e652b2a674e2 191 Pfam PF06572 Protein of unknown function (DUF1131) 24 191 3.2E-82 T 28-03-2018 IPR010938 Protein of unknown function DUF1131 WM46_RS05645 f71082fa25959b72baeb21bff72c2175 236 Pfam PF02613 Nitrate reductase delta subunit 42 155 2.2E-12 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS05645 f71082fa25959b72baeb21bff72c2175 236 SUPERFAMILY SSF89155 5 163 1.78E-32 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS05645 f71082fa25959b72baeb21bff72c2175 236 Gene3D G3DSA:1.10.3480.10 4 203 4.4E-31 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS05645 f71082fa25959b72baeb21bff72c2175 236 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 8 161 1.2E-54 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.30.70.20 90 181 7.9E-13 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 328 640 3.0E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.50.50.60 423 495 3.0E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.50.50.60 496 582 4.8E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.40.50.720 325 422 1.1E-18 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 189 652 4.8E-259 T 28-03-2018 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.30.70.20 59 89 2.3E-10 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 205 313 3.3E-36 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.30.70.20 7 58 3.1E-5 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 PRINTS PR00419 Adrenodoxin reductase family signature 505 518 2.9E-37 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 PRINTS PR00419 Adrenodoxin reductase family signature 329 351 2.9E-37 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 PRINTS PR00419 Adrenodoxin reductase family signature 471 485 2.9E-37 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 PRINTS PR00419 Adrenodoxin reductase family signature 352 365 2.9E-37 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 PRINTS PR00419 Adrenodoxin reductase family signature 394 404 2.9E-37 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Pfam PF13247 4Fe-4S dicluster domain 55 144 5.3E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:3.50.50.60 583 653 5.9E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 Gene3D G3DSA:1.10.1060.10 182 324 2.3E-36 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 SUPERFAMILY SSF54862 197 294 3.1E-40 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 SUPERFAMILY SSF54862 1 161 3.1E-40 T 28-03-2018 WM46_RS00915 2135549ec3f47fee6ef11c9216cbfe26 653 SUPERFAMILY SSF51971 327 582 4.3E-68 T 28-03-2018 WM46_RS14060 cd7ac54879dbaed2e92863dbe042e4e6 265 Gene3D G3DSA:3.40.50.300 1 245 1.1E-61 T 28-03-2018 WM46_RS14060 cd7ac54879dbaed2e92863dbe042e4e6 265 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS14060 cd7ac54879dbaed2e92863dbe042e4e6 265 SMART SM00382 36 224 2.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS14060 cd7ac54879dbaed2e92863dbe042e4e6 265 Pfam PF00005 ABC transporter 27 176 2.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS14060 cd7ac54879dbaed2e92863dbe042e4e6 265 SUPERFAMILY SSF52540 13 239 1.5E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 SUPERFAMILY SSF56935 23 370 3.4E-76 T 28-03-2018 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 325 342 2.7E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 155 166 2.7E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 53 64 2.7E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 99 109 2.7E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 246 258 2.7E-19 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 Gene3D G3DSA:2.40.160.10 11 370 2.2E-51 T 28-03-2018 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00183 E.coli/Salmonella-type porin signature 23 39 2.3E-70 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00183 E.coli/Salmonella-type porin signature 52 70 2.3E-70 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00183 E.coli/Salmonella-type porin signature 99 121 2.3E-70 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00183 E.coli/Salmonella-type porin signature 153 175 2.3E-70 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00183 E.coli/Salmonella-type porin signature 252 269 2.3E-70 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 PRINTS PR00183 E.coli/Salmonella-type porin signature 280 299 2.3E-70 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 325 341 - T 28-03-2018 IPR013793 Porin, Gram-negative type, conserved site WM46_RS09755 8b1ce59459b36cdb33ba7c4eecb59ae4 370 Pfam PF00267 Gram-negative porin 28 370 2.0E-144 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 Gene3D G3DSA:3.40.50.10730 157 328 6.1E-28 T 28-03-2018 WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 SUPERFAMILY SSF50129 1 179 1.1E-45 T 28-03-2018 IPR011032 GroES-like WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 SUPERFAMILY SSF51735 136 305 9.98E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 SMART SM00829 9 335 8.8E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 Gene3D G3DSA:3.90.180.10 1 156 4.6E-47 T 28-03-2018 WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 Pfam PF00107 Zinc-binding dehydrogenase 174 300 3.5E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS09380 1ba5bc98cdeeee84f9cd5e5ec3e03d4e 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 133 2.3E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 Pfam PF14864 Alkyl sulfatase C-terminal 534 658 1.4E-42 T 28-03-2018 IPR029229 Alkyl sulfatase, C-terminal WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 SUPERFAMILY SSF56281 29 528 1.96E-152 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 Gene3D G3DSA:3.30.1050.10 528 658 2.5E-33 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 Gene3D G3DSA:3.60.15.10 103 404 4.9E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 SMART SM00849 129 351 4.5E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 SUPERFAMILY SSF55718 536 658 4.94E-38 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 Pfam PF00753 Metallo-beta-lactamase superfamily 126 351 1.1E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS06695 de51a2fc548aac96f5fde8932474af95 658 Pfam PF14863 Alkyl sulfatase dimerisation 388 526 4.1E-61 T 28-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 WM46_RS23505 67d439ed3ad3019ad54e4197482ea78d 266 Gene3D G3DSA:3.40.50.720 1 226 8.6E-30 T 28-03-2018 WM46_RS23505 67d439ed3ad3019ad54e4197482ea78d 266 SUPERFAMILY SSF51735 1 231 3.8E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23505 67d439ed3ad3019ad54e4197482ea78d 266 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 161 5.6E-19 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS16275 f80725d7928e13bd959163248638e468 567 SUPERFAMILY SSF51338 414 477 9.5E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS16275 f80725d7928e13bd959163248638e468 567 ProSitePatterns PS00145 Urease active site. 317 333 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 SUPERFAMILY SSF51338 1 177 2.68E-66 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS16275 f80725d7928e13bd959163248638e468 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 567 3.1E-293 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 1.1E-34 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 1.1E-34 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 1.1E-34 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 1.1E-34 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 SUPERFAMILY SSF51556 130 431 7.99E-197 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS16275 f80725d7928e13bd959163248638e468 567 SUPERFAMILY SSF51556 480 567 7.99E-197 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS16275 f80725d7928e13bd959163248638e468 567 Gene3D G3DSA:3.20.20.140 422 553 1.8E-42 T 28-03-2018 WM46_RS16275 f80725d7928e13bd959163248638e468 567 Gene3D G3DSA:3.20.20.140 143 421 4.0E-163 T 28-03-2018 WM46_RS16275 f80725d7928e13bd959163248638e468 567 Gene3D G3DSA:2.30.40.10 65 142 1.7E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS16275 f80725d7928e13bd959163248638e468 567 Hamap MF_01953 Urease subunit alpha [ureC]. 2 567 56.615 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 119 1.2E-56 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 ProSitePatterns PS01120 Urease nickel ligands signature. 127 140 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16275 f80725d7928e13bd959163248638e468 567 Pfam PF01979 Amidohydrolase family 125 453 1.8E-83 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS21370 66fe3d1b31a1a45209876e799066452a 543 TIGRFAM TIGR01013 2a58: sodium-dependent inorganic phosphate (Pi) transporter 67 520 3.7E-162 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 WM46_RS21370 66fe3d1b31a1a45209876e799066452a 543 SUPERFAMILY SSF109755 321 531 7.85E-23 T 28-03-2018 WM46_RS21370 66fe3d1b31a1a45209876e799066452a 543 Gene3D G3DSA:1.20.58.220 322 432 6.5E-8 T 28-03-2018 WM46_RS21370 66fe3d1b31a1a45209876e799066452a 543 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 308 2.7E-133 T 28-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 WM46_RS21370 66fe3d1b31a1a45209876e799066452a 543 Pfam PF02690 Na+/Pi-cotransporter 13 147 9.8E-36 T 28-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 WM46_RS21370 66fe3d1b31a1a45209876e799066452a 543 Gene3D G3DSA:1.20.58.220 433 543 1.1E-9 T 28-03-2018 WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 Pfam PF08402 TOBE domain 270 342 1.5E-12 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 SMART SM00382 26 209 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 SUPERFAMILY SSF52540 1 240 7.99E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 Pfam PF00005 ABC transporter 17 159 3.8E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 Gene3D G3DSA:2.40.50.140 281 334 6.2E-9 T 28-03-2018 WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 SUPERFAMILY SSF50331 234 350 3.64E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 Gene3D G3DSA:2.40.50.100 239 280 2.9E-6 T 28-03-2018 WM46_RS24435 4b69f8b227f988d3e77f4f5a3f269c5b 357 Gene3D G3DSA:3.40.50.300 1 238 1.1E-73 T 28-03-2018 WM46_RS16500 5184c0aa683c181c04226c117b8ce845 329 Gene3D G3DSA:3.40.50.1100 36 137 5.3E-29 T 28-03-2018 WM46_RS16500 5184c0aa683c181c04226c117b8ce845 329 SUPERFAMILY SSF53686 11 320 1.31E-93 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS16500 5184c0aa683c181c04226c117b8ce845 329 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 312 5.2E-79 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS16500 5184c0aa683c181c04226c117b8ce845 329 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 28 323 6.8E-115 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 WM46_RS16500 5184c0aa683c181c04226c117b8ce845 329 Gene3D G3DSA:3.40.50.1100 138 328 1.1E-44 T 28-03-2018 WM46_RS16500 5184c0aa683c181c04226c117b8ce845 329 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 49 62 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 Pfam PF00232 Glycosyl hydrolase family 1 2 459 2.2E-154 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 Gene3D G3DSA:3.20.20.80 1 463 1.4E-152 T 28-03-2018 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 SUPERFAMILY SSF51445 2 461 1.53E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 357 365 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 378 389 1.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 424 436 1.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 291 305 1.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 399 416 1.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15320 363c42b5ff615b841c80de692d42b9ed 464 PRINTS PR00131 Glycosyl hydrolase family 1 signature 357 365 1.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS25325 e5aa1f37f0e689ac895047d269c63f44 282 Pfam PF00950 ABC 3 transport family 11 266 5.7E-79 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 WM46_RS25325 e5aa1f37f0e689ac895047d269c63f44 282 SUPERFAMILY SSF81345 4 262 5.89E-39 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS25325 e5aa1f37f0e689ac895047d269c63f44 282 Gene3D G3DSA:1.10.3470.10 3 278 1.1E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 Pfam PF13247 4Fe-4S dicluster domain 106 207 2.0E-22 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 Gene3D G3DSA:3.30.70.20 52 126 1.6E-14 T 28-03-2018 WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 Gene3D G3DSA:3.30.70.20 169 303 4.9E-14 T 28-03-2018 WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 Gene3D G3DSA:3.30.70.20 27 51 0.026 T 28-03-2018 WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 SUPERFAMILY SSF54862 38 325 1.59E-70 T 28-03-2018 WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 Gene3D G3DSA:3.30.70.20 127 168 3.4E-17 T 28-03-2018 WM46_RS15940 f5fd33f23fae3bf1e372e4d58fe72811 328 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 1 26 3.3E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 497 7.7E-256 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 499 1.6E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 SUPERFAMILY SSF110921 391 499 1.7E-25 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 SMART SM00917 369 500 7.5E-36 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 SUPERFAMILY SSF51569 1 290 2.2E-96 T 28-03-2018 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 42.338 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 Gene3D G3DSA:3.20.20.70 1 330 2.0E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS14455 5aafc6ef485d58b7637b2218b4dc5027 523 Pfam PF00682 HMGL-like 5 273 1.9E-104 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 SUPERFAMILY SSF51556 8 346 1.74E-147 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 ProSitePatterns PS00483 Dihydroorotase signature 2. 249 260 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 ProSitePatterns PS00482 Dihydroorotase signature 1. 15 23 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 Gene3D G3DSA:3.20.20.140 14 348 8.3E-56 T 28-03-2018 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 8 347 8.4E-163 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 Pfam PF01979 Amidohydrolase family 15 307 1.9E-22 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 Hamap MF_00219 Dihydroorotase [pyrC]. 6 347 61.427 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS08850 c98b241dfc4af09efc8a2234eb54af5a 348 PIRSF PIRSF001237 4 348 3.5E-141 T 28-03-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 Pfam PF00411 Ribosomal protein S11 19 128 1.9E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 7 129 32.678 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.0E-55 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 Gene3D G3DSA:3.30.420.80 3 129 1.2E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 SUPERFAMILY SSF53137 14 129 6.08E-48 T 28-03-2018 WM46_RS17430 b3f2d60e9479262be013fc0afb0be596 129 PIRSF PIRSF002131 1 129 1.7E-53 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Gene3D G3DSA:3.40.50.140 1 150 4.0E-38 T 28-03-2018 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 SUPERFAMILY SSF57783 616 654 6.46E-7 T 28-03-2018 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 SMART SM00437 272 556 2.9E-68 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Gene3D G3DSA:1.10.460.10 152 383 9.9E-42 T 28-03-2018 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 SMART SM00493 1 123 4.0E-19 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Pfam PF01751 Toprim domain 2 130 1.9E-19 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Gene3D G3DSA:1.10.460.10 384 607 1.0E-27 T 28-03-2018 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 SMART SM00436 123 218 2.2E-29 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 664 1.9E-252 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 188 206 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 97 110 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 1.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 619 649 1.2E-7 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Gene3D G3DSA:3.30.65.10 608 663 2.5E-12 T 28-03-2018 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 309 324 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 SUPERFAMILY SSF56712 1 603 6.28E-181 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain WM46_RS15670 10b76c15b4cd4f0de3b32438c817b634 669 Pfam PF01131 DNA topoisomerase 152 590 2.9E-119 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 SUPERFAMILY SSF56719 30 521 4.71E-184 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Gene3D G3DSA:1.10.268.10 376 497 1.4E-50 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Gene3D G3DSA:3.90.199.10 34 285 7.7E-116 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 WM46_RS02010 8252a33579456f127401826cc311d85e 878 SMART SM00434 11 499 0.0 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 584 9.2E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 737 2.0E-15 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 645 688 1.7E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 793 839 5.8E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 789 3.9E-14 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 637 3.5E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 840 0.0 T 28-03-2018 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 841 24.702 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Gene3D G3DSA:3.90.199.10 286 375 3.7E-9 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 WM46_RS02010 8252a33579456f127401826cc311d85e 878 Gene3D G3DSA:2.120.10.90 533 856 4.3E-135 T 28-03-2018 WM46_RS02010 8252a33579456f127401826cc311d85e 878 SUPERFAMILY SSF101904 533 850 3.01E-112 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal WM46_RS02010 8252a33579456f127401826cc311d85e 878 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 506 7.3E-155 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 420 503 9.3E-19 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 457 474 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 Gene3D G3DSA:3.30.1360.60 442 517 4.0E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 72 370 8.5E-88 T 28-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 Pfam PF00367 phosphotransferase system, EIIB 447 479 9.7E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 SUPERFAMILY SSF55604 444 517 4.71E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS25140 521372948e977966ee9fcb1ba5fd4423 518 Pfam PF02378 Phosphotransferase system, EIIC 21 359 9.8E-94 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 Pfam PF13378 Enolase C-terminal domain-like 133 295 1.1E-24 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 173 204 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 SMART SM00922 130 223 2.1E-19 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 Gene3D G3DSA:3.20.20.120 116 321 5.0E-39 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 SUPERFAMILY SSF51604 117 308 5.76E-51 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 SUPERFAMILY SSF54826 2 111 4.91E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 Gene3D G3DSA:3.30.390.10 1 115 7.3E-29 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS06120 35b8803bf67bb09c4dbda5174aaa2a23 321 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 2 109 1.3E-28 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 PRINTS PR00315 GTP-binding elongation factor signature 2 15 1.3E-7 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 PRINTS PR00315 GTP-binding elongation factor signature 70 81 1.3E-7 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 PRINTS PR00315 GTP-binding elongation factor signature 54 64 1.3E-7 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 PRINTS PR00315 GTP-binding elongation factor signature 107 116 1.3E-7 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 607 1.2E-254 T 28-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:3.40.50.300 50 171 1.4E-21 T 28-03-2018 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Pfam PF03144 Elongation factor Tu domain 2 189 256 1.8E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:3.40.50.300 1 49 1.9E-9 T 28-03-2018 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:2.40.30.10 282 335 8.2E-8 T 28-03-2018 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 SUPERFAMILY SSF46785 416 484 2.99E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:1.10.10.10 489 545 2.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 SUPERFAMILY SSF46785 551 607 3.26E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 SUPERFAMILY SSF50465 269 351 1.83E-7 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Pfam PF09107 Elongation factor SelB, winged helix 560 605 8.3E-20 T 28-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Pfam PF09106 Elongation factor SelB, winged helix 424 480 1.3E-15 T 28-03-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:2.40.30.10 172 281 8.7E-21 T 28-03-2018 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Pfam PF00009 Elongation factor Tu GTP binding domain 2 162 1.7E-32 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:1.10.10.10 548 606 1.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 Gene3D G3DSA:1.10.10.10 417 480 6.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 SUPERFAMILY SSF50447 175 293 1.77E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS20365 ab77e47557c68fcb50a6e38d5fce366f 615 SUPERFAMILY SSF52540 2 165 8.52E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 Pfam PF00571 CBS domain 278 326 1.6E-4 T 28-03-2018 IPR000644 CBS domain WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 Pfam PF01595 Domain of unknown function DUF21 13 184 1.2E-48 T 28-03-2018 IPR002550 Domain of unknown function DUF21 WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 SUPERFAMILY SSF56176 340 422 3.27E-21 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 SUPERFAMILY SSF54631 192 329 9.35E-22 T 28-03-2018 WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 Gene3D G3DSA:3.10.580.10 185 338 1.1E-19 T 28-03-2018 WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 Pfam PF03471 Transporter associated domain 344 418 3.0E-18 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 Gene3D G3DSA:3.30.465.10 339 428 5.1E-19 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS00170 306b0a27758082ae3cd6bc7f3476eb3d 428 SMART SM01091 342 420 8.0E-25 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 SUPERFAMILY SSF82679 1 97 1.57E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 Gene3D G3DSA:2.30.30.30 111 162 2.0E-5 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 SMART SM00738 1 100 2.8E-33 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 159 3.8E-67 T 28-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 Pfam PF02357 Transcription termination factor nusG 3 96 1.4E-19 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 Gene3D G3DSA:3.30.70.940 1 98 1.5E-18 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS18980 4dc5eea23f63694f14a9e3ce305a5e1e 162 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 1 162 47.259 T 28-03-2018 IPR010215 Transcription antitermination protein RfaH GO:0006355 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 252 309 5.3E-19 T 28-03-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 Gene3D G3DSA:2.30.130.10 250 313 6.6E-15 T 28-03-2018 IPR002478 PUA domain GO:0003723 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 SUPERFAMILY SSF55120 10 246 8.06E-86 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 33 180 1.0E-57 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 SUPERFAMILY SSF88697 251 310 4.57E-14 T 28-03-2018 IPR015947 PUA-like domain WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 Gene3D G3DSA:3.30.2350.10 10 230 1.2E-81 T 28-03-2018 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 12 219 7.5E-95 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 11 309 18.936 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS16755 5188331e06a6b3cf7009f5995fc190ee 314 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.7E-20 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 TIGRFAM TIGR01810 betA: choline dehydrogenase 4 537 2.7E-296 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 SUPERFAMILY SSF54373 295 477 2.35E-65 T 28-03-2018 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 1 554 60.937 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 259 273 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 PIRSF PIRSF000137 1 542 7.3E-138 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 Gene3D G3DSA:4.10.450.10 37 102 2.3E-24 T 28-03-2018 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 Pfam PF00732 GMC oxidoreductase 3 300 5.0E-102 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 Gene3D G3DSA:3.30.560.10 103 490 4.2E-99 T 28-03-2018 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 SUPERFAMILY SSF51905 2 293 4.03E-86 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 SUPERFAMILY SSF51905 476 535 4.03E-86 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11725 572417ce71e0b5807642b2cab695879a 558 Pfam PF05199 GMC oxidoreductase 393 527 3.8E-41 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 WM46_RS09065 5fba95cced0b67b4174e2fd4bc035c70 1173 Pfam PF14331 ImcF-related N-terminal domain 205 449 1.9E-61 T 28-03-2018 IPR025743 ImcF-related, N-terminal domain WM46_RS09065 5fba95cced0b67b4174e2fd4bc035c70 1173 SUPERFAMILY SSF52540 135 301 1.98E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09065 5fba95cced0b67b4174e2fd4bc035c70 1173 Gene3D G3DSA:3.40.50.300 135 401 1.7E-7 T 28-03-2018 WM46_RS09065 5fba95cced0b67b4174e2fd4bc035c70 1173 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 32 1170 2.8E-280 T 28-03-2018 IPR017731 Type VI secretion system, IcmF WM46_RS09065 5fba95cced0b67b4174e2fd4bc035c70 1173 Pfam PF06744 Type VI secretion protein IcmF C-terminal 925 1121 1.6E-48 T 28-03-2018 IPR010623 Type VI secretion system IcmF, C-terminal WM46_RS09065 5fba95cced0b67b4174e2fd4bc035c70 1173 Pfam PF06761 Intracellular multiplication and human macrophage-killing 505 817 6.7E-68 T 28-03-2018 IPR009612 ImcF-related WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 SUPERFAMILY SSF52440 1 113 1.22E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 447 2.2E-250 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 SMART SM00878 336 441 4.3E-65 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 8.0E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 Gene3D G3DSA:3.40.50.20 1 123 1.1E-51 T 28-03-2018 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 2.7E-38 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 1.6E-85 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 Gene3D G3DSA:3.30.470.20 210 444 1.2E-96 T 28-03-2018 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 Gene3D G3DSA:3.30.1490.20 124 209 6.3E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 SUPERFAMILY SSF56059 83 347 1.75E-68 T 28-03-2018 WM46_RS17215 fb3a5456990beef0e1dbf04230fc10a6 449 SUPERFAMILY SSF51246 331 444 9.42E-44 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 8.0E-36 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 SMART SM00846 2 150 3.3E-83 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 SUPERFAMILY SSF51735 3 166 1.09E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 313 1.2E-60 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 Gene3D G3DSA:3.30.360.10 160 315 7.8E-60 T 28-03-2018 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 1.3E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.3E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 1.3E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 1.3E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 1.3E-31 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 SUPERFAMILY SSF55347 150 314 1.22E-61 T 28-03-2018 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 PIRSF PIRSF000149 1 333 4.3E-119 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 325 7.2E-135 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS06360 ff06e97b59b60a534971f4b218ba6d6d 333 Gene3D G3DSA:3.40.50.720 1 159 8.6E-72 T 28-03-2018 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 Gene3D G3DSA:3.40.190.10 27 157 1.0E-24 T 28-03-2018 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 Pfam PF13416 Bacterial extracellular solute-binding protein 53 346 2.6E-41 T 28-03-2018 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 Gene3D G3DSA:3.40.190.10 158 399 2.4E-39 T 28-03-2018 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 SUPERFAMILY SSF53850 32 398 1.38E-96 T 28-03-2018 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 360 379 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 154 173 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 39 57 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 73 91 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 174 193 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 236 255 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 133 152 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 PRINTS PR00181 Maltose binding protein signature 302 323 2.4E-99 T 28-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 WM46_RS21555 31109282ea000ddb1365e71fc660093a 399 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 136 153 - T 28-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 Pfam PF03928 Haem-degrading 204 326 1.7E-25 T 28-03-2018 IPR005624 Haem-degrading WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 174 1.0E-47 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 SUPERFAMILY SSF89028 1 174 2.16E-51 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 PIRSF PIRSF036411 1 332 2.0E-92 T 28-03-2018 IPR009221 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, bifunctional PduO WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 SUPERFAMILY SSF143744 197 329 1.44E-36 T 28-03-2018 WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 Pfam PF01923 Cobalamin adenosyltransferase 3 166 1.6E-51 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 156 6.0E-47 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 WM46_RS03465 0348ff33d7c167436928a01f50b10549 335 Gene3D G3DSA:1.20.1200.10 12 183 4.5E-49 T 28-03-2018 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 Hamap MF_01618 3-ketoacyl-CoA thiolase [fadI]. 2 436 73.768 T 28-03-2018 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 TIGRFAM TIGR02446 FadI: acetyl-CoA C-acyltransferase FadI 7 436 1.0E-265 T 28-03-2018 IPR012806 Acetyl-CoA C-acyltransferase FadI GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 Pfam PF00108 Thiolase, N-terminal domain 15 288 2.9E-59 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 ProSitePatterns PS00737 Thiolases signature 2. 382 398 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 17 434 4.6E-133 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 Pfam PF02803 Thiolase, C-terminal domain 297 434 1.6E-36 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 SUPERFAMILY SSF53901 297 434 5.6E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 Gene3D G3DSA:3.40.47.10 302 433 2.2E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 SUPERFAMILY SSF53901 15 295 2.78E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 PIRSF PIRSF000429 9 436 1.3E-125 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 95 113 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 ProSitePatterns PS00099 Thiolases active site. 417 430 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 WM46_RS01480 fd924bc5995e93dd7165344c71802f8e 436 Gene3D G3DSA:3.40.47.10 7 301 3.1E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS21245 13c2f0239815ce85c8fed2c796e85c33 162 Hamap MF_01181 Regulator of sigma D [rsd]. 1 151 40.581 T 28-03-2018 IPR023785 Regulator of RNA polymerase sigma(70) subunit, Rsd WM46_RS21245 13c2f0239815ce85c8fed2c796e85c33 162 PIRSF PIRSF016548 1 158 2.3E-57 T 28-03-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 WM46_RS21245 13c2f0239815ce85c8fed2c796e85c33 162 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 1 147 2.4E-51 T 28-03-2018 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 WM46_RS10550 727d55101189b305ba95676dc88b997a 161 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 158 36.654 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 WM46_RS10550 727d55101189b305ba95676dc88b997a 161 Gene3D G3DSA:3.30.70.640 2 158 1.8E-68 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 WM46_RS10550 727d55101189b305ba95676dc88b997a 161 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 1.4E-73 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 WM46_RS10550 727d55101189b305ba95676dc88b997a 161 SUPERFAMILY SSF55040 11 155 1.44E-61 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 WM46_RS10550 727d55101189b305ba95676dc88b997a 161 Pfam PF01967 MoaC family 15 150 9.3E-55 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 WM46_RS04835 4644a5ec1c3cfd8dc72a73d4649e1286 164 Gene3D G3DSA:1.10.3290.10 36 157 1.1E-9 T 28-03-2018 IPR003812 Fido domain WM46_RS04835 4644a5ec1c3cfd8dc72a73d4649e1286 164 SUPERFAMILY SSF140931 52 124 1.96E-5 T 28-03-2018 IPR003812 Fido domain WM46_RS04835 4644a5ec1c3cfd8dc72a73d4649e1286 164 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 11 129 3.0E-42 T 28-03-2018 IPR006440 Death on curing protein GO:0016301 WM46_RS04835 4644a5ec1c3cfd8dc72a73d4649e1286 164 Pfam PF02661 Fic/DOC family 10 93 3.9E-9 T 28-03-2018 IPR003812 Fido domain WM46_RS24360 1012d4ab127b1a797353a2935308a322 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 41 374 4.9E-48 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS24360 1012d4ab127b1a797353a2935308a322 398 SUPERFAMILY SSF53686 35 351 3.14E-59 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS24360 1012d4ab127b1a797353a2935308a322 398 Gene3D G3DSA:3.40.50.1100 76 183 1.7E-30 T 28-03-2018 WM46_RS24360 1012d4ab127b1a797353a2935308a322 398 Gene3D G3DSA:3.40.50.1100 184 396 3.7E-26 T 28-03-2018 WM46_RS24360 1012d4ab127b1a797353a2935308a322 398 TIGRFAM TIGR03528 2_3_DAP_am_ly: diaminopropionate ammonia-lyase 6 392 4.9E-193 T 28-03-2018 IPR019871 Diaminopropionate ammonia-lyase, subgroup GO:0008838 WM46_RS24360 1012d4ab127b1a797353a2935308a322 398 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 23 391 2.0E-203 T 28-03-2018 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 WM46_RS15040 1486073a45930a204eec844182673e06 464 PRINTS PR00171 Sugar transporter signature 26 36 2.2E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 PRINTS PR00171 Sugar transporter signature 262 272 2.2E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 PRINTS PR00171 Sugar transporter signature 375 387 2.2E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 PRINTS PR00171 Sugar transporter signature 109 128 2.2E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 PRINTS PR00171 Sugar transporter signature 352 373 2.2E-23 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 Pfam PF00083 Sugar (and other) transporter 18 450 3.5E-142 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 SUPERFAMILY SSF103473 13 448 1.44E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS15040 1486073a45930a204eec844182673e06 464 Gene3D G3DSA:1.20.1250.20 232 463 3.0E-42 T 28-03-2018 WM46_RS15040 1486073a45930a204eec844182673e06 464 Gene3D G3DSA:1.20.1250.20 3 231 2.7E-37 T 28-03-2018 WM46_RS15040 1486073a45930a204eec844182673e06 464 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 7 447 4.7E-152 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS15040 1486073a45930a204eec844182673e06 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 307 323 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS25580 ed4729cca7e48060dc24c9493a4e00fb 519 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 519 229.044 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM46_RS25580 ed4729cca7e48060dc24c9493a4e00fb 519 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 6 516 2.6E-281 T 28-03-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM46_RS25580 ed4729cca7e48060dc24c9493a4e00fb 519 SUPERFAMILY SSF55931 4 514 7.85E-204 T 28-03-2018 WM46_RS25580 ed4729cca7e48060dc24c9493a4e00fb 519 Pfam PF04262 Glutamate-cysteine ligase 9 380 3.4E-172 T 28-03-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 Gene3D G3DSA:3.30.565.10 318 486 1.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 303 2.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 SUPERFAMILY SSF55874 293 449 4.06E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 4 454 8.0E-121 T 28-03-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 SUPERFAMILY SSF47384 221 304 8.83E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 449 7.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 SMART SM00388 238 304 2.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 SMART SM00387 347 458 1.7E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11885 67405cfd8a82284dd8658ba5868d51d0 489 Gene3D G3DSA:1.10.287.130 228 300 7.2E-13 T 28-03-2018 WM46_RS14965 02b304c48e66056ef711244d93a1a1fe 227 SMART SM00382 28 213 1.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS14965 02b304c48e66056ef711244d93a1a1fe 227 Gene3D G3DSA:3.40.50.300 1 222 1.6E-49 T 28-03-2018 WM46_RS14965 02b304c48e66056ef711244d93a1a1fe 227 SUPERFAMILY SSF52540 2 219 2.44E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14965 02b304c48e66056ef711244d93a1a1fe 227 Pfam PF00005 ABC transporter 19 164 3.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 Gene3D G3DSA:3.40.50.2000 262 472 1.3E-31 T 28-03-2018 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 Pfam PF08323 Starch synthase catalytic domain 2 233 1.4E-71 T 28-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 Hamap MF_00484 Glycogen synthase [glgA]. 1 476 46.84 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 Pfam PF00534 Glycosyl transferases group 1 287 438 5.6E-13 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 475 3.3E-175 T 28-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 Gene3D G3DSA:3.40.50.2000 16 261 7.2E-12 T 28-03-2018 WM46_RS18015 0026e4c6cb35acd54a8ffa030b57d733 477 SUPERFAMILY SSF53756 5 476 4.54E-116 T 28-03-2018 WM46_RS19605 8c586305732710246df281eb70a119d5 416 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 13 397 1.5E-152 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 16 39 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 154 174 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 350 369 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 329 347 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 195 217 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 88 108 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 43 62 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 295 314 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 PRINTS PR00166 Aromatic amino acid permease signature 234 253 6.1E-101 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS19605 8c586305732710246df281eb70a119d5 416 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 23 39 - T 28-03-2018 IPR013061 Tryptophan/tryrosine permease, conserved site WM46_RS19605 8c586305732710246df281eb70a119d5 416 Pfam PF03222 Tryptophan/tyrosine permease family 8 403 7.3E-146 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 Gene3D G3DSA:3.40.50.720 2 115 9.9E-29 T 28-03-2018 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 297 8.7E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 Gene3D G3DSA:3.40.50.720 116 300 3.9E-51 T 28-03-2018 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 327 3.8E-35 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 SUPERFAMILY SSF52283 2 135 4.16E-45 T 28-03-2018 WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 SUPERFAMILY SSF51735 102 298 1.97E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS06290 1151553edd1fc01021f585c31ea93a49 329 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 Gene3D G3DSA:3.40.50.300 309 608 4.3E-51 T 28-03-2018 WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 Pfam PF12848 ABC transporter 217 297 1.4E-28 T 28-03-2018 IPR032781 ABC-transporter extension domain WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 Gene3D G3DSA:3.40.50.300 85 294 5.1E-42 T 28-03-2018 WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 SMART SM00382 26 223 4.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 SMART SM00382 337 506 2.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 SUPERFAMILY SSF52540 294 516 5.2E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 SUPERFAMILY SSF52540 119 253 2.02E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 SUPERFAMILY SSF52540 2 92 2.02E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 Pfam PF00005 ABC transporter 17 178 6.0E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 Pfam PF00005 ABC transporter 328 459 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS17650 e70ba18f05a69dc43991be9e46b7de55 633 Gene3D G3DSA:3.40.50.300 4 73 8.4E-11 T 28-03-2018 WM46_RS19615 0b2c5a2d958cbfd2bf4844b49fa5903f 24 TIGRFAM TIGR02616 tnaC_leader: tryptophanase leader peptide 10 24 5.8E-7 T 28-03-2018 IPR012620 Tryptophanese operon leader peptide GO:0031554|GO:0031556 WM46_RS19615 0b2c5a2d958cbfd2bf4844b49fa5903f 24 Pfam PF08053 Tryptophanase operon leader peptide 1 24 5.5E-9 T 28-03-2018 IPR012620 Tryptophanese operon leader peptide GO:0031554|GO:0031556 WM46_RS26035 308d94c0bddab20efec15e2a8c0b7433 177 Gene3D G3DSA:3.30.870.10 23 177 1.6E-29 T 28-03-2018 WM46_RS26035 308d94c0bddab20efec15e2a8c0b7433 177 SMART SM00155 111 138 1.9E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS26035 308d94c0bddab20efec15e2a8c0b7433 177 Pfam PF13091 PLD-like domain 43 167 3.3E-25 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS26035 308d94c0bddab20efec15e2a8c0b7433 177 SUPERFAMILY SSF56024 27 172 6.95E-38 T 28-03-2018 WM46_RS09110 5deb05cb5951a0f2fd59bebe49888464 375 Pfam PF13473 Cupredoxin-like domain 14 115 2.5E-24 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain WM46_RS09110 5deb05cb5951a0f2fd59bebe49888464 375 Pfam PF09375 Imelysin 135 367 2.8E-44 T 28-03-2018 IPR018976 Peptidase M75, Imelysin WM46_RS09110 5deb05cb5951a0f2fd59bebe49888464 375 Gene3D G3DSA:3.90.20.10 134 370 6.3E-4 T 28-03-2018 WM46_RS09110 5deb05cb5951a0f2fd59bebe49888464 375 SUPERFAMILY SSF49503 16 116 1.07E-5 T 28-03-2018 IPR008972 Cupredoxin WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 Pfam PF00271 Helicase conserved C-terminal domain 243 351 3.6E-28 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 SMART SM00490 270 351 2.0E-30 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 Gene3D G3DSA:3.40.50.300 235 421 1.5E-43 T 28-03-2018 WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 SMART SM00487 28 234 2.9E-52 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 Gene3D G3DSA:3.40.50.300 3 234 1.7E-50 T 28-03-2018 WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 51.009 T 28-03-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 SUPERFAMILY SSF52540 84 363 7.64E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19275 f46d27cb766bdd6adcd152caf8a7f260 422 Pfam PF00270 DEAD/DEAH box helicase 33 206 1.5E-44 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 2.4E-58 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 58 69 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 Gene3D G3DSA:3.90.1170.10 1 136 5.2E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 1.7E-46 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 133 37.894 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 SUPERFAMILY SSF54686 3 133 3.27E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 PRINTS PR00060 Ribosomal protein L16 signature 87 116 9.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 PRINTS PR00060 Ribosomal protein L16 signature 23 35 9.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 PRINTS PR00060 Ribosomal protein L16 signature 57 86 9.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 PRINTS PR00060 Ribosomal protein L16 signature 41 52 9.6E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17510 9ca18dc7b9b89f80a362850de52e64fc 136 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 81 92 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS04060 0f019fd082490fdc06ebda2d003df826 167 Pfam PF00210 Ferritin-like domain 9 142 2.4E-22 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 WM46_RS04060 0f019fd082490fdc06ebda2d003df826 167 SUPERFAMILY SSF47240 6 157 1.53E-34 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS04060 0f019fd082490fdc06ebda2d003df826 167 Gene3D G3DSA:1.20.1260.10 4 162 2.3E-22 T 28-03-2018 IPR012347 Ferritin-related WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 40 902 0.0 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SMART SM00831 48 121 5.2E-5 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SUPERFAMILY SSF81653 172 274 8.5E-29 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Gene3D G3DSA:2.70.150.10 57 276 3.9E-46 T 28-03-2018 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Pfam PF00122 E1-E2 ATPase 163 355 3.6E-47 T 28-03-2018 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SUPERFAMILY SSF81665 276 369 2.48E-103 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SUPERFAMILY SSF81665 692 900 2.48E-103 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SUPERFAMILY SSF81665 51 159 2.48E-103 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Gene3D G3DSA:3.40.1110.10 337 550 2.7E-40 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Pfam PF00689 Cation transporting ATPase, C-terminus 726 892 3.0E-14 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Pfam PF00690 Cation transporter/ATPase, N-terminus 60 116 1.1E-13 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SUPERFAMILY SSF81660 344 547 1.79E-42 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 SUPERFAMILY SSF56784 536 687 8.87E-38 T 28-03-2018 IPR023214 HAD-like domain WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Gene3D G3DSA:1.20.1110.10 564 897 3.0E-56 T 28-03-2018 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 610 732 2.9E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 127 410 7.5E-39 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 377 383 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 Pfam PF00702 haloacid dehalogenase-like hydrolase 371 657 1.6E-19 T 28-03-2018 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 771 787 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 305 324 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 751 764 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 288 304 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 701 716 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 856 877 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 409 422 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 719 730 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS23285 f4e7f451ca00defecf155dd723002191 902 PRINTS PR01836 Magnesium-transporting ATPase signature 806 827 5.9E-85 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 WM46_RS18255 bb738d0509e95cbaf135a37efc5dd614 85 SUPERFAMILY SSF47336 3 83 1.06E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS18255 bb738d0509e95cbaf135a37efc5dd614 85 Gene3D G3DSA:1.10.1200.10 2 85 3.6E-15 T 28-03-2018 WM46_RS18255 bb738d0509e95cbaf135a37efc5dd614 85 Pfam PF00550 Phosphopantetheine attachment site 8 62 1.5E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS01010 78e2d10efdaaca8a575dac0b54ff5685 453 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 444 1.2E-201 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 WM46_RS01010 78e2d10efdaaca8a575dac0b54ff5685 453 PIRSF PIRSF018788 1 453 5.5E-232 T 28-03-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 WM46_RS01010 78e2d10efdaaca8a575dac0b54ff5685 453 Gene3D G3DSA:3.20.20.70 143 449 4.0E-153 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS01010 78e2d10efdaaca8a575dac0b54ff5685 453 Gene3D G3DSA:2.30.170.30 1 53 1.5E-26 T 28-03-2018 WM46_RS01010 78e2d10efdaaca8a575dac0b54ff5685 453 Gene3D G3DSA:1.10.220.70 56 140 2.4E-29 T 28-03-2018 WM46_RS12795 dc7f6ac4a3e8522662fa1834e4cd63eb 230 SUPERFAMILY SSF46785 5 62 2.57E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12795 dc7f6ac4a3e8522662fa1834e4cd63eb 230 Pfam PF08279 HTH domain 7 60 1.0E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 WM46_RS12795 dc7f6ac4a3e8522662fa1834e4cd63eb 230 Pfam PF13280 WYL domain 138 227 2.2E-16 T 28-03-2018 IPR026881 WYL domain WM46_RS12795 dc7f6ac4a3e8522662fa1834e4cd63eb 230 Gene3D G3DSA:1.10.10.10 2 64 5.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11320 dd733a0ede755fcda20fdcfb29eab4ed 302 SMART SM00062 41 273 3.0E-67 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS11320 dd733a0ede755fcda20fdcfb29eab4ed 302 Gene3D G3DSA:3.40.190.10 170 302 4.8E-19 T 28-03-2018 WM46_RS11320 dd733a0ede755fcda20fdcfb29eab4ed 302 Gene3D G3DSA:3.40.190.10 4 169 9.0E-32 T 28-03-2018 WM46_RS11320 dd733a0ede755fcda20fdcfb29eab4ed 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 271 6.3E-48 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS11320 dd733a0ede755fcda20fdcfb29eab4ed 302 SUPERFAMILY SSF53850 11 274 2.26E-63 T 28-03-2018 WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 Gene3D G3DSA:3.60.20.10 2 193 3.0E-48 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 Pfam PF13537 Glutamine amidotransferase domain 48 165 1.8E-41 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 PIRSF PIRSF001589 363 508 4.7E-29 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 PIRSF PIRSF001589 1 365 1.1E-108 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 373 4.5E-125 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 Pfam PF00733 Asparagine synthase 211 366 5.6E-60 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 SUPERFAMILY SSF56235 1 196 3.09E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 Gene3D G3DSA:3.40.50.620 194 514 3.5E-91 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11245 866c7fddd60297e1a95617128faac18a 554 SUPERFAMILY SSF52402 210 479 3.2E-76 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 SUPERFAMILY SSF52540 71 291 2.7E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 SUPERFAMILY SSF54211 258 272 9.86E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 SUPERFAMILY SSF54211 306 457 9.86E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 SMART SM00382 94 248 4.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 454 2.6E-239 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 Gene3D G3DSA:3.30.230.10 288 457 1.6E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 Pfam PF13481 AAA domain 88 225 2.7E-14 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 Hamap MF_01498 DNA repair protein RadA [radA]. 22 458 43.322 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 127 144 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 216 244 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 177 201 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 325 348 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 11 35 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 86 114 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 PRINTS PR01874 DNA repair protein radA signature 251 277 1.6E-93 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 Pfam PF13541 Subunit ChlI of Mg-chelatase 348 433 1.5E-9 T 28-03-2018 WM46_RS24130 d99fec72b58f1bf88b266442519f6e52 460 Gene3D G3DSA:3.40.50.300 76 286 4.8E-40 T 28-03-2018 WM46_RS16330 3d815285c71a0812b1b6a5f71cec1873 254 Gene3D G3DSA:2.40.30.10 10 132 2.0E-27 T 28-03-2018 WM46_RS16330 3d815285c71a0812b1b6a5f71cec1873 254 Pfam PF04954 Siderophore-interacting protein 142 253 7.0E-20 T 28-03-2018 IPR007037 Siderophore-interacting protein WM46_RS16330 3d815285c71a0812b1b6a5f71cec1873 254 Pfam PF08021 Siderophore-interacting FAD-binding domain 22 132 9.8E-32 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting WM46_RS16330 3d815285c71a0812b1b6a5f71cec1873 254 SUPERFAMILY SSF63380 3 137 7.62E-14 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS16330 3d815285c71a0812b1b6a5f71cec1873 254 Gene3D G3DSA:3.40.50.80 133 254 1.5E-22 T 28-03-2018 WM46_RS14845 985d87b116a716f59146beff2706b035 229 SUPERFAMILY SSF46894 126 226 6.8E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS14845 985d87b116a716f59146beff2706b035 229 SUPERFAMILY SSF52172 2 129 2.99E-38 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS14845 985d87b116a716f59146beff2706b035 229 Gene3D G3DSA:3.40.50.2300 1 122 1.6E-33 T 28-03-2018 WM46_RS14845 985d87b116a716f59146beff2706b035 229 Pfam PF00072 Response regulator receiver domain 6 115 4.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS14845 985d87b116a716f59146beff2706b035 229 SMART SM00862 150 226 2.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS14845 985d87b116a716f59146beff2706b035 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 226 4.3E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS14845 985d87b116a716f59146beff2706b035 229 SMART SM00448 4 115 3.1E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS14845 985d87b116a716f59146beff2706b035 229 Gene3D G3DSA:1.10.10.10 123 228 2.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22565 40ad8a3f2eb6e1882523d805b75ab00a 142 SUPERFAMILY SSF51306 17 136 2.27E-31 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS22565 40ad8a3f2eb6e1882523d805b75ab00a 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 64 75 5.4E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS22565 40ad8a3f2eb6e1882523d805b75ab00a 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 53 63 5.4E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS22565 40ad8a3f2eb6e1882523d805b75ab00a 142 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 92 104 5.4E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS22565 40ad8a3f2eb6e1882523d805b75ab00a 142 Gene3D G3DSA:2.10.109.10 22 138 9.3E-23 T 28-03-2018 WM46_RS22565 40ad8a3f2eb6e1882523d805b75ab00a 142 Pfam PF00717 Peptidase S24-like 59 119 1.7E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 209 3.4E-36 T 28-03-2018 IPR023214 HAD-like domain WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 7 240 36.561 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 10 239 1.6E-96 T 28-03-2018 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 SUPERFAMILY SSF56784 3 239 2.71E-58 T 28-03-2018 IPR023214 HAD-like domain WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 Gene3D G3DSA:3.40.50.1000 2 36 0.0057 T 28-03-2018 IPR023214 HAD-like domain WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 115 204 5.6E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 Gene3D G3DSA:3.40.50.1000 99 247 5.3E-37 T 28-03-2018 IPR023214 HAD-like domain WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 123 136 6.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 170 6.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 6.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 192 6.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 Gene3D G3DSA:1.10.150.240 37 98 7.6E-21 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS17755 af921626edc3bd2a9f66d2c0eed64942 252 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 95 209 2.2E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 Pfam PF07729 FCD domain 80 210 6.1E-20 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 70 8.0E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 SUPERFAMILY SSF48008 76 216 6.02E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 SUPERFAMILY SSF46785 13 74 2.97E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 Gene3D G3DSA:1.10.10.10 4 71 1.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 SMART SM00345 12 70 1.9E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 SMART SM00895 80 212 2.0E-16 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS25710 a47a418d9c5d76a825145dcc95d96e8b 230 Gene3D G3DSA:1.20.120.530 72 214 3.9E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.6E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 Pfam PF00106 short chain dehydrogenase 10 203 1.1E-62 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 Gene3D G3DSA:3.40.50.720 1 251 3.8E-68 T 28-03-2018 WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 SUPERFAMILY SSF51735 9 252 2.37E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23450 0871453cfe29f4fa84041ba24aa4bd97 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS09530 ab244f4d19593cfb92b73c42189b24e1 659 TIGRFAM TIGR03432 yjhG_yagF: putative dehydratase, YjhG/YagF family 7 648 0.0 T 28-03-2018 IPR017798 Dehydratase YjhG/YagF WM46_RS09530 ab244f4d19593cfb92b73c42189b24e1 659 Pfam PF00920 Dehydratase family 85 600 3.7E-115 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS09530 ab244f4d19593cfb92b73c42189b24e1 659 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 529 540 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS09530 ab244f4d19593cfb92b73c42189b24e1 659 SUPERFAMILY SSF143975 6 424 2.22E-89 T 28-03-2018 WM46_RS09530 ab244f4d19593cfb92b73c42189b24e1 659 SUPERFAMILY SSF52016 440 642 2.75E-39 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS09530 ab244f4d19593cfb92b73c42189b24e1 659 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 162 172 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS02090 f80bf1f92548cf71243540e4e3bac8c5 351 Pfam PF02424 ApbE family 42 325 3.9E-78 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 WM46_RS02090 f80bf1f92548cf71243540e4e3bac8c5 351 SUPERFAMILY SSF143631 35 346 3.66E-94 T 28-03-2018 IPR003374 ApbE-like domain WM46_RS02090 f80bf1f92548cf71243540e4e3bac8c5 351 PIRSF PIRSF006268 1 347 8.0E-88 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 WM46_RS02090 f80bf1f92548cf71243540e4e3bac8c5 351 Gene3D G3DSA:3.10.520.10 41 339 1.1E-51 T 28-03-2018 WM46_RS06180 305c11d23bffd5c9f9fb610aa0170443 229 SMART SM00882 6 219 1.4E-80 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS06180 305c11d23bffd5c9f9fb610aa0170443 229 Gene3D G3DSA:3.40.1080.10 2 226 8.0E-82 T 28-03-2018 WM46_RS06180 305c11d23bffd5c9f9fb610aa0170443 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 3.3E-117 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 WM46_RS06180 305c11d23bffd5c9f9fb610aa0170443 229 SUPERFAMILY SSF100950 2 224 6.58E-80 T 28-03-2018 WM46_RS06180 305c11d23bffd5c9f9fb610aa0170443 229 Pfam PF01144 Coenzyme A transferase 8 217 5.6E-71 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS06180 305c11d23bffd5c9f9fb610aa0170443 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 263 9.1E-24 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 227 238 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 5 270 9.7E-110 T 28-03-2018 WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 201 217 - T 28-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 SUPERFAMILY SSF56219 5 271 4.19E-89 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 5 271 4.5E-94 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 31 40 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 WM46_RS08200 f5dde705f8a20b10a4993be82aca6b22 272 Gene3D G3DSA:3.60.10.10 4 272 2.0E-52 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS13335 d23345c93cdf529e56c5c121e6957830 210 SUPERFAMILY SSF56529 2 204 1.27E-53 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13335 d23345c93cdf529e56c5c121e6957830 210 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 3 203 6.6E-85 T 28-03-2018 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 WM46_RS13335 d23345c93cdf529e56c5c121e6957830 210 Gene3D G3DSA:3.90.850.10 1 210 1.4E-46 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13335 d23345c93cdf529e56c5c121e6957830 210 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 5 204 3.5E-39 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 23 941 20.043 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Gene3D G3DSA:1.10.4050.10 525 633 9.8E-24 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Gene3D G3DSA:1.10.4050.10 1 106 2.3E-18 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 SUPERFAMILY SSF81301 521 811 1.54E-89 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Gene3D G3DSA:3.30.460.10 109 280 8.8E-57 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Gene3D G3DSA:3.30.460.10 634 807 8.0E-60 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Gene3D G3DSA:1.20.120.330 281 436 1.5E-50 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Pfam PF08335 GlnD PII-uridylyltransferase 293 432 2.2E-46 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Pfam PF08335 GlnD PII-uridylyltransferase 821 913 4.2E-12 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 SUPERFAMILY SSF81301 27 282 9.81E-87 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 SUPERFAMILY SSF81593 811 939 6.28E-34 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 SUPERFAMILY SSF81593 283 432 3.77E-46 T 28-03-2018 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 28 266 9.7E-95 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 549 800 3.0E-101 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 WM46_RS16200 762d3cbbef3277f7809a3660e63a1649 941 Gene3D G3DSA:1.20.120.330 808 941 2.7E-37 T 28-03-2018 WM46_RS00105 df2b161ddf01b0b92ae1c3c0de81d66f 423 Gene3D G3DSA:1.10.443.10 230 412 7.3E-20 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS00105 df2b161ddf01b0b92ae1c3c0de81d66f 423 SUPERFAMILY SSF56349 123 407 1.44E-53 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS00105 df2b161ddf01b0b92ae1c3c0de81d66f 423 Gene3D G3DSA:1.10.150.130 112 229 9.1E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS00105 df2b161ddf01b0b92ae1c3c0de81d66f 423 Pfam PF00589 Phage integrase family 233 396 2.5E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS00105 df2b161ddf01b0b92ae1c3c0de81d66f 423 Pfam PF13356 Arm DNA-binding domain 22 109 2.6E-16 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS09075 19169e61f04a3758d48691ebc051c5a7 159 SUPERFAMILY SSF141452 3 158 4.05E-33 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09075 19169e61f04a3758d48691ebc051c5a7 159 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 157 4.9E-59 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09075 19169e61f04a3758d48691ebc051c5a7 159 Gene3D G3DSA:2.30.110.20 2 159 1.6E-45 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09075 19169e61f04a3758d48691ebc051c5a7 159 Pfam PF05638 Type VI secretion system effector, Hcp 18 143 4.7E-21 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09535 c8bf222b577a22b00e37fa02d65bba0c 449 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 449 6.1E-197 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS09535 c8bf222b577a22b00e37fa02d65bba0c 449 PIRSF PIRSF002746 1 449 2.2E-173 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS09535 c8bf222b577a22b00e37fa02d65bba0c 449 Pfam PF02447 GntP family permease 1 448 2.3E-181 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 SUPERFAMILY SSF53697 5 547 3.34E-228 T 28-03-2018 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 1.5E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 1.5E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 1.5E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 1.5E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 1.5E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 1.5E-55 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 Pfam PF00342 Phosphoglucose isomerase 52 541 1.6E-256 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 Gene3D G3DSA:1.10.1390.10 513 548 2.2E-21 T 28-03-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 524 43.231 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 Gene3D G3DSA:3.40.50.10490 259 512 1.8E-125 T 28-03-2018 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 Gene3D G3DSA:3.40.50.10490 1 144 8.1E-50 T 28-03-2018 WM46_RS21500 2c320bd60b12e20e6972fd8dcdd4a31b 548 Gene3D G3DSA:3.40.50.10490 145 258 6.4E-54 T 28-03-2018 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 Gene3D G3DSA:1.10.287.400 378 437 6.2E-29 T 28-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 SUPERFAMILY SSF69864 190 444 1.57E-80 T 28-03-2018 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 443 76.883 T 28-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 SUPERFAMILY SSF52402 3 186 1.63E-34 T 28-03-2018 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 Gene3D G3DSA:3.90.1260.10 179 374 3.1E-55 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 Gene3D G3DSA:3.40.50.620 2 178 6.9E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 1.5E-168 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS16790 24f663be0f04ad80a62d5a3ae7d78b7e 447 Pfam PF00764 Arginosuccinate synthase 16 410 1.4E-56 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 Gene3D G3DSA:1.20.1250.20 1 200 5.0E-26 T 28-03-2018 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 ProSitePatterns PS00896 LacY family proton/sugar symporters signature 1. 64 78 - T 28-03-2018 IPR018457 LacY/RafB permease family, conserved site GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 SUPERFAMILY SSF103473 5 400 7.67E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 214 242 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 315 334 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 260 281 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 103 125 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 145 163 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 68 97 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 284 310 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 PRINTS PR00174 LacY proton/sugar symporter family signature 346 366 7.3E-110 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 Pfam PF01306 LacY proton/sugar symporter 2 407 7.2E-210 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 Gene3D G3DSA:1.20.1250.20 206 405 5.4E-17 T 28-03-2018 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 ProSitePatterns PS00897 LacY family proton/sugar symporters signature 2. 280 294 - T 28-03-2018 IPR018457 LacY/RafB permease family, conserved site GO:0006810|GO:0016020 WM46_RS13150 b43228def0b7b5cf0cab37d8ea0d0899 417 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 6 401 1.7E-209 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 940 951 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 SUPERFAMILY SSF46548 397 563 1.05E-18 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Gene3D G3DSA:1.10.1060.10 858 966 2.0E-9 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Gene3D G3DSA:1.10.1060.10 411 547 3.0E-24 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 817 835 7.1E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 554 576 7.1E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 678 702 7.1E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 SUPERFAMILY SSF46548 869 967 2.35E-9 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 456 534 5.9E-16 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 SUPERFAMILY SSF51395 289 408 3.82E-13 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 SUPERFAMILY SSF51395 204 259 3.82E-13 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 SUPERFAMILY SSF51395 43 140 3.82E-13 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Gene3D G3DSA:3.20.20.70 43 410 8.5E-10 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 SUPERFAMILY SSF51971 553 788 5.71E-48 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Gene3D G3DSA:3.50.50.60 696 857 1.7E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Gene3D G3DSA:3.50.50.60 548 647 2.1E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Gene3D G3DSA:3.50.50.60 648 695 3.0E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 807 829 1.5E-15 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 780 796 1.5E-15 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 555 574 1.5E-15 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 682 700 1.5E-15 T 28-03-2018 WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 TIGRFAM TIGR03315 Se_ygfK: putative selenate reductase, YgfK subunit 2 1029 0.0 T 28-03-2018 IPR017701 Putative selenate reductase YgfK WM46_RS24325 55710ee616c9c6814f86865a48f4d946 1034 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 554 842 5.5E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS18205 94f268af1e10135fc4aa8d9dec3e3244 81 Gene3D G3DSA:3.30.110.40 4 81 9.1E-29 T 28-03-2018 IPR001455 TusA-like domain WM46_RS18205 94f268af1e10135fc4aa8d9dec3e3244 81 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 28-03-2018 IPR001455 TusA-like domain WM46_RS18205 94f268af1e10135fc4aa8d9dec3e3244 81 Pfam PF01206 Sulfurtransferase TusA 10 79 1.8E-24 T 28-03-2018 IPR001455 TusA-like domain WM46_RS18205 94f268af1e10135fc4aa8d9dec3e3244 81 SUPERFAMILY SSF64307 5 80 1.96E-26 T 28-03-2018 IPR001455 TusA-like domain WM46_RS18205 94f268af1e10135fc4aa8d9dec3e3244 81 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 3 81 29.504 T 28-03-2018 IPR022931 Sulfur carrier protein TusA GO:0002143|GO:0097163 WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 Pfam PF00005 ABC transporter 280 434 1.2E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 Pfam PF00005 ABC transporter 29 180 6.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 SMART SM00382 288 483 0.39 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 SMART SM00382 38 228 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 SUPERFAMILY SSF52540 278 486 6.92E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 Gene3D G3DSA:3.40.50.300 10 259 3.9E-55 T 28-03-2018 WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 SUPERFAMILY SSF52540 12 233 2.81E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21025 9a150456e0a1694f4b1cd262e87a55f7 504 Gene3D G3DSA:3.40.50.300 265 498 5.0E-35 T 28-03-2018 WM46_RS23355 525e4d252dcc2ee60652e2328873d510 150 SUPERFAMILY SSF51197 1 149 3.02E-43 T 28-03-2018 WM46_RS23355 525e4d252dcc2ee60652e2328873d510 150 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 149 1.7E-58 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family WM46_RS23355 525e4d252dcc2ee60652e2328873d510 150 Gene3D G3DSA:2.60.120.370 1 150 1.0E-55 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family WM46_RS23355 525e4d252dcc2ee60652e2328873d510 150 Pfam PF04074 Domain of unknown function (DUF386) 1 147 1.4E-46 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family WM46_RS03610 05174487d6f05c239261ca91bb68718f 93 TIGRFAM TIGR01165 cbiN: cobalt transport protein 1 85 7.6E-38 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 WM46_RS03610 05174487d6f05c239261ca91bb68718f 93 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 93 44.05 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 WM46_RS03610 05174487d6f05c239261ca91bb68718f 93 Pfam PF02553 Cobalt transport protein component CbiN 5 69 2.3E-28 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 WM46_RS18790 bea7828eb18812a06a9b9214cd4f1a89 413 Gene3D G3DSA:1.50.10.10 1 413 1.0E-79 T 28-03-2018 WM46_RS18790 bea7828eb18812a06a9b9214cd4f1a89 413 Hamap MF_00998 Sulfoquinovose isomerase. 1 413 84.63 T 28-03-2018 IPR030875 Sulfoquinovose isomerase GO:0061593 MetaCyc: PWY-7446 WM46_RS18790 bea7828eb18812a06a9b9214cd4f1a89 413 SUPERFAMILY SSF48208 3 409 3.17E-116 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS18790 bea7828eb18812a06a9b9214cd4f1a89 413 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 32 387 8.5E-129 T 28-03-2018 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 Pfam PF13531 Bacterial extracellular solute-binding protein 38 286 2.5E-40 T 28-03-2018 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 151 159 - T 28-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 53 65 - T 28-03-2018 IPR000957 Sulphate/thiosulphate-binding, conserved site WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 SUPERFAMILY SSF53850 24 332 4.43E-81 T 28-03-2018 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 15 332 1.0E-183 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 Gene3D G3DSA:3.40.190.10 24 132 2.0E-17 T 28-03-2018 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 Gene3D G3DSA:3.40.190.10 133 258 1.4E-23 T 28-03-2018 WM46_RS01070 fcd762389c8aa99e633940b9f6d21393 338 Gene3D G3DSA:3.40.190.10 259 335 2.7E-17 T 28-03-2018 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 SUPERFAMILY SSF52009 125 245 1.22E-36 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 SUPERFAMILY SSF51621 249 549 3.66E-110 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 Gene3D G3DSA:1.10.274.10 24 145 3.0E-35 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 Gene3D G3DSA:3.50.30.10 146 245 3.6E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 Gene3D G3DSA:3.20.20.60 250 573 8.3E-103 T 28-03-2018 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 126 2.7E-29 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 SUPERFAMILY SSF47831 23 143 1.57E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 3.5E-31 T 28-03-2018 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 3.5E-31 T 28-03-2018 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 3.5E-31 T 28-03-2018 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 3.5E-31 T 28-03-2018 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 566 4.8E-270 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 541 1.6E-126 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 3.3E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 PIRSF PIRSF000732 1 574 1.0E-217 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 WM46_RS01125 ee001e06b1f0cfa32bc6deea616b70bf 575 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 21 68 2.0E-16 T 28-03-2018 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 Gene3D G3DSA:3.30.70.920 72 164 5.1E-15 T 28-03-2018 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 Pfam PF01037 Lrp/AsnC ligand binding domain 102 157 5.3E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 SUPERFAMILY SSF46785 21 80 1.45E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 Gene3D G3DSA:1.10.10.10 21 71 3.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 ProSitePatterns PS00519 AsnC-type HTH domain signature. 39 65 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 SMART SM00344 21 127 2.0E-34 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 48 2.8E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 48 67 2.8E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 37 2.8E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS11920 65139164a296e2e85e20578f6a8aed09 166 SUPERFAMILY SSF54909 86 163 6.3E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS00135 d908aab4faa1595469695c69990dff24 160 Pfam PF01668 SmpB protein 14 157 2.4E-56 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 WM46_RS00135 d908aab4faa1595469695c69990dff24 160 SUPERFAMILY SSF74982 8 138 3.14E-50 T 28-03-2018 IPR023620 Small protein B WM46_RS00135 d908aab4faa1595469695c69990dff24 160 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site WM46_RS00135 d908aab4faa1595469695c69990dff24 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 156 1.6E-53 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 WM46_RS00135 d908aab4faa1595469695c69990dff24 160 Gene3D G3DSA:2.40.280.10 14 133 2.9E-45 T 28-03-2018 IPR023620 Small protein B WM46_RS00135 d908aab4faa1595469695c69990dff24 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 160 71.938 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 WM46_RS00135 d908aab4faa1595469695c69990dff24 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 8.0E-69 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 WM46_RS14680 d0a13da0b2c8781300e731c10556d161 304 SUPERFAMILY SSF53590 3 300 1.02E-96 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain WM46_RS14680 d0a13da0b2c8781300e731c10556d161 304 Hamap MF_01432 Non-specific ribonucleoside hydrolase RihC [rihC]. 1 304 70.627 T 28-03-2018 IPR022976 Non-specific ribonucleoside hydrolase RihC GO:0016798 WM46_RS14680 d0a13da0b2c8781300e731c10556d161 304 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 293 6.8E-84 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain WM46_RS14680 d0a13da0b2c8781300e731c10556d161 304 Gene3D G3DSA:3.90.245.10 1 303 4.7E-100 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 43 60 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 3.7E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 3.7E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 3.7E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 3.7E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 SUPERFAMILY SSF51569 2 301 1.05E-82 T 28-03-2018 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 SMART SM01130 6 300 2.5E-96 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 169 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 Gene3D G3DSA:3.20.20.70 1 301 5.4E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 Pfam PF00701 Dihydrodipicolinate synthetase family 6 298 1.6E-71 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18000 5568a1a75025f05f175b91f646469c01 301 PIRSF PIRSF001365 2 301 1.1E-81 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SMART SM00487 23 307 2.9E-4 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 Pfam PF13307 Helicase C-terminal domain 531 688 5.6E-25 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 Pfam PF06733 DEAD_2 197 264 9.4E-8 T 28-03-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SMART SM00491 544 676 1.4E-38 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SMART SM00488 18 294 0.0082 T 28-03-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 Pfam PF00270 DEAD/DEAH box helicase 31 95 8.6E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 Gene3D G3DSA:3.40.50.300 503 687 6.3E-5 T 28-03-2018 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 Gene3D G3DSA:3.40.50.300 24 483 3.0E-27 T 28-03-2018 WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SUPERFAMILY SSF52540 199 271 4.94E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SUPERFAMILY SSF52540 46 97 4.94E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SUPERFAMILY SSF52540 451 465 4.94E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10460 83d02d1b303aa73a99b0f4215b8b4135 716 SUPERFAMILY SSF52540 500 670 4.94E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Gene3D G3DSA:3.30.930.10 223 531 1.2E-120 T 28-03-2018 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 SUPERFAMILY SSF52954 530 636 6.19E-34 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 SUPERFAMILY SSF81271 3 61 2.29E-16 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Gene3D G3DSA:3.40.50.800 532 642 1.2E-29 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 7.0E-247 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Pfam PF02824 TGS domain 4 61 4.5E-13 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 SUPERFAMILY SSF55186 63 241 4.06E-65 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Gene3D G3DSA:3.30.980.10 146 222 4.1E-17 T 28-03-2018 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Gene3D G3DSA:3.30.980.10 65 145 1.5E-22 T 28-03-2018 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Pfam PF03129 Anticodon binding domain 541 630 1.3E-23 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 528 4.8E-51 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 8.1E-55 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 8.1E-55 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 8.1E-55 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 8.1E-55 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 8.1E-55 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Gene3D G3DSA:3.10.20.30 1 64 5.3E-20 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 634 34.176 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 SUPERFAMILY SSF55681 243 525 5.81E-97 T 28-03-2018 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 SMART SM00863 170 219 2.6E-19 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 WM46_RS08040 2344bafdb18133b9681ee4e80961f555 642 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 219 4.1E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 80 94 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 SUPERFAMILY SSF53686 5 390 1.96E-141 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 Gene3D G3DSA:3.40.50.1100 197 397 7.5E-37 T 28-03-2018 WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 375 5.9E-49 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 PIRSF PIRSF001413 1 397 3.5E-171 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 2 391 48.884 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 Gene3D G3DSA:3.40.50.1100 9 196 8.1E-45 T 28-03-2018 WM46_RS05835 4a1ab9181bcf5696f00f2c35237d2943 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 8 389 5.6E-188 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS03550 55415a6c55b61a6ff556f9eb6ee485e8 319 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 8 308 5.3E-75 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 WM46_RS03550 55415a6c55b61a6ff556f9eb6ee485e8 319 Pfam PF03186 CobD/Cbib protein 7 297 2.2E-105 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 WM46_RS03550 55415a6c55b61a6ff556f9eb6ee485e8 319 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 318 105.835 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 WM46_RS05975 58068b84f08a600e9cc1b0777f027f81 379 SUPERFAMILY SSF69118 213 377 6.91E-11 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS05975 58068b84f08a600e9cc1b0777f027f81 379 SUPERFAMILY SSF69118 78 187 1.27E-11 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS05975 58068b84f08a600e9cc1b0777f027f81 379 Gene3D G3DSA:1.20.1290.10 221 379 2.3E-10 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS05975 58068b84f08a600e9cc1b0777f027f81 379 Gene3D G3DSA:1.20.1290.10 48 189 0.029 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS01745 eba1772e749b6be1a5c9badd49886674 199 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 3 195 44.141 T 28-03-2018 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 WM46_RS01745 eba1772e749b6be1a5c9badd49886674 199 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 80 172 1.0E-45 T 28-03-2018 WM46_RS01745 eba1772e749b6be1a5c9badd49886674 199 Pfam PF13023 HD domain 11 159 4.1E-17 T 28-03-2018 IPR006674 HD domain WM46_RS01745 eba1772e749b6be1a5c9badd49886674 199 SUPERFAMILY SSF109604 2 193 6.85E-45 T 28-03-2018 WM46_RS01745 eba1772e749b6be1a5c9badd49886674 199 Gene3D G3DSA:1.10.3210.10 1 199 1.5E-54 T 28-03-2018 WM46_RS01745 eba1772e749b6be1a5c9badd49886674 199 SMART SM00471 26 151 5.2E-7 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 SUPERFAMILY SSF50249 1 66 3.92E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 PIRSF PIRSF002599 1 73 9.9E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.4E-29 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 SMART SM00357 3 67 5.4E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 68 1.3E-43 T 28-03-2018 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 Gene3D G3DSA:2.40.50.140 1 73 9.5E-27 T 28-03-2018 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 PRINTS PR00050 Cold shock protein signature 25 34 2.8E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS10025 d47cb1775811bcf767df7d701de20c2b 73 PRINTS PR00050 Cold shock protein signature 40 58 2.8E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS18570 3fc3ace31810cedb42c2e91e9cb8f916 419 Pfam PF06134 L-rhamnose isomerase (RhaA) 3 418 1.9E-237 T 28-03-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 WM46_RS18570 3fc3ace31810cedb42c2e91e9cb8f916 419 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 9 418 0.0 T 28-03-2018 WM46_RS18570 3fc3ace31810cedb42c2e91e9cb8f916 419 SUPERFAMILY SSF51658 4 418 3.83E-85 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS18570 3fc3ace31810cedb42c2e91e9cb8f916 419 Gene3D G3DSA:3.20.20.150 1 419 8.1E-112 T 28-03-2018 WM46_RS18570 3fc3ace31810cedb42c2e91e9cb8f916 419 TIGRFAM TIGR01748 rhaA: L-rhamnose isomerase 5 418 2.1E-246 T 28-03-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 WM46_RS18570 3fc3ace31810cedb42c2e91e9cb8f916 419 Hamap MF_00541 L-rhamnose isomerase [rhaA]. 1 419 277.954 T 28-03-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 WM46_RS16430 bc6da0c039d6a33e09f48be72c8b3053 101 Gene3D G3DSA:1.20.5.1230 3 88 7.5E-5 T 28-03-2018 WM46_RS16430 bc6da0c039d6a33e09f48be72c8b3053 101 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 101 1.5E-31 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB WM46_RS16545 c30bab42e6d8cc08b61b5f2f38968cb0 523 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 119 521 3.5E-145 T 28-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 WM46_RS16545 c30bab42e6d8cc08b61b5f2f38968cb0 523 Hamap MF_02031 Galactarate dehydratase (L-threo-forming) [garD]. 2 523 80.147 T 28-03-2018 IPR032893 Galactarate dehydratase (L-threo-forming) GarD, Enterobacteriaceae GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 WM46_RS16545 c30bab42e6d8cc08b61b5f2f38968cb0 523 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 15 523 1.9E-281 T 28-03-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 WM46_RS16545 c30bab42e6d8cc08b61b5f2f38968cb0 523 Pfam PF08666 SAF domain 22 92 3.9E-14 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 WM46_RS16545 c30bab42e6d8cc08b61b5f2f38968cb0 523 SMART SM00858 22 92 3.3E-14 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 WM46_RS07870 744a9200274ccb764a5d0b067703ec0a 136 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 135 1.1E-43 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 WM46_RS07870 744a9200274ccb764a5d0b067703ec0a 136 Hamap MF_01936 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [menI]. 1 136 45.647 T 28-03-2018 IPR030863 1,4-dihydroxy-2-naphthoyl-CoA hydrolase, MenI GO:0009234|GO:0061522 KEGG: 00130+3.1.2.28|MetaCyc: PWY-5837 WM46_RS07870 744a9200274ccb764a5d0b067703ec0a 136 Gene3D G3DSA:3.10.129.10 1 136 7.4E-26 T 28-03-2018 WM46_RS07870 744a9200274ccb764a5d0b067703ec0a 136 SUPERFAMILY SSF54637 1 133 4.87E-27 T 28-03-2018 IPR029069 HotDog domain WM46_RS07870 744a9200274ccb764a5d0b067703ec0a 136 Pfam PF03061 Thioesterase superfamily 50 127 4.4E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 SUPERFAMILY SSF141523 376 429 3.79E-20 T 28-03-2018 WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 SUPERFAMILY SSF141523 485 534 3.79E-20 T 28-03-2018 WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 Gene3D G3DSA:1.10.101.10 237 354 2.0E-21 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 Pfam PF03734 L,D-transpeptidase catalytic domain 378 544 5.5E-31 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 SUPERFAMILY SSF47090 236 271 6.51E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 SUPERFAMILY SSF47090 315 357 6.51E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 Pfam PF01471 Putative peptidoglycan binding domain 315 349 1.7E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS09780 143d54b99383dd873e81c589fbe2aa4f 616 Gene3D G3DSA:2.40.440.10 375 554 1.1E-23 T 28-03-2018 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 268 1.7E-107 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 269 44.405 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 129 218 9.8E-32 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 SMART SM01232 129 221 1.0E-49 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 Gene3D G3DSA:3.20.190.10 1 130 1.0E-37 T 28-03-2018 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 Gene3D G3DSA:1.10.8.50 131 269 4.9E-51 T 28-03-2018 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 3.3E-32 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 SUPERFAMILY SSF57716 217 269 4.56E-17 T 28-03-2018 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 Pfam PF06827 Zinc finger found in FPG and IleRS 241 269 5.4E-9 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 244 268 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 SUPERFAMILY SSF81624 2 138 8.77E-44 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 SMART SM00898 2 115 1.7E-53 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM46_RS20155 8a836148bb82ed82881e55643e1b51d3 269 SUPERFAMILY SSF46946 130 222 4.32E-31 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 2 235 5.3E-123 T 28-03-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 5.8E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 2.7E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 2.7E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 Pfam PF07840 FadR C-terminal domain 72 234 1.5E-72 T 28-03-2018 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 SUPERFAMILY SSF46785 11 88 2.48E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 SMART SM00345 12 71 5.9E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 239 161.555 T 28-03-2018 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 SUPERFAMILY SSF48008 79 230 3.79E-64 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 Gene3D G3DSA:1.20.120.530 80 239 5.9E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS05165 a8f0f3b643c28c35b80019be063525eb 239 Gene3D G3DSA:1.10.10.10 1 79 7.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 SUPERFAMILY SSF56601 35 292 2.08E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 210 225 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 174 199 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 39 63 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 112 137 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 148 172 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 227 242 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 PRINTS PR00118 Beta-lactamase class A signature 70 87 1.9E-70 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 Gene3D G3DSA:3.40.710.10 33 293 1.5E-35 T 28-03-2018 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 ProSitePatterns PS00146 Beta-lactamase class-A active site. 72 87 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 WM46_RS05095 cd6eab15545f19181d055d6c9d0da1e5 294 Pfam PF13354 Beta-lactamase enzyme family 60 266 7.7E-39 T 28-03-2018 WM46_RS09830 5129d919355f376eea38998eca6f7450 325 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 13 318 9.3E-116 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 WM46_RS09830 5129d919355f376eea38998eca6f7450 325 Gene3D G3DSA:3.40.50.300 33 253 1.3E-8 T 28-03-2018 WM46_RS09830 5129d919355f376eea38998eca6f7450 325 SUPERFAMILY SSF52540 46 163 5.31E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09830 5129d919355f376eea38998eca6f7450 325 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 19 322 3.4E-120 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 WM46_RS09830 5129d919355f376eea38998eca6f7450 325 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 325 41.26 T 28-03-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 WM46_RS18400 60a82a9d8c26e10823c1d98037520fca 176 SUPERFAMILY SSF56235 2 172 2.44E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS18400 60a82a9d8c26e10823c1d98037520fca 176 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 41.738 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 WM46_RS18400 60a82a9d8c26e10823c1d98037520fca 176 Gene3D G3DSA:3.60.20.10 2 172 1.1E-31 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS18400 60a82a9d8c26e10823c1d98037520fca 176 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 172 2.7E-86 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 WM46_RS18400 60a82a9d8c26e10823c1d98037520fca 176 Pfam PF00227 Proteasome subunit 2 167 7.3E-23 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 WM46_RS18400 60a82a9d8c26e10823c1d98037520fca 176 PIRSF PIRSF039093 1 175 2.9E-87 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 WM46_RS06730 30fd91129ff0ce22a12a14692b42ecf2 226 SUPERFAMILY SSF103501 3 225 1.44E-69 T 28-03-2018 IPR023234 NarG-like domain WM46_RS06730 30fd91129ff0ce22a12a14692b42ecf2 226 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 226 1.2E-122 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS06730 30fd91129ff0ce22a12a14692b42ecf2 226 Gene3D G3DSA:1.20.950.20 2 217 1.0E-40 T 28-03-2018 WM46_RS06730 30fd91129ff0ce22a12a14692b42ecf2 226 Pfam PF02665 Nitrate reductase gamma subunit 6 225 1.7E-78 T 28-03-2018 IPR023234 NarG-like domain WM46_RS07735 0f1c1725229d8ccce7ef9b31fe112462 261 Gene3D G3DSA:1.20.950.20 60 261 2.7E-33 T 28-03-2018 WM46_RS07735 0f1c1725229d8ccce7ef9b31fe112462 261 Pfam PF01292 Prokaryotic cytochrome b561 69 256 2.0E-25 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM46_RS07735 0f1c1725229d8ccce7ef9b31fe112462 261 SUPERFAMILY SSF81342 63 259 1.1E-23 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 SUPERFAMILY SSF55447 164 250 7.72E-12 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 152 1.7E-20 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 TIGRFAM TIGR03312 Se_sel_red_FAD: probable selenate reductase, FAD-binding subunit 2 256 2.4E-129 T 28-03-2018 IPR017698 Probable selenate reductase, FAD-binding subunit WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 Gene3D G3DSA:3.30.390.50 159 258 2.7E-13 T 28-03-2018 WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 Gene3D G3DSA:3.30.465.10 54 156 3.8E-14 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 167 248 2.2E-4 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 SMART SM01092 161 251 4.0E-12 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 SUPERFAMILY SSF56176 4 154 8.18E-24 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS24315 eb7609abe2dff312468b147676e63dd0 259 Gene3D G3DSA:3.30.43.10 3 47 2.7E-4 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 PRINTS PR01484 Pertactin virulence factor family signature 838 861 1.5E-8 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 PRINTS PR01484 Pertactin virulence factor family signature 664 682 1.5E-8 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 PRINTS PR01484 Pertactin virulence factor family signature 819 836 1.5E-8 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 PRINTS PR01484 Pertactin virulence factor family signature 904 929 1.5E-8 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 Gene3D G3DSA:2.160.20.20 39 212 9.7E-4 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 Gene3D G3DSA:2.160.20.20 213 616 3.3E-38 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 SMART SM00869 684 938 4.0E-34 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 SUPERFAMILY SSF51126 446 611 1.19E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 SUPERFAMILY SSF51126 49 403 1.19E-23 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 Pfam PF03212 Pertactin 489 610 3.7E-36 T 28-03-2018 IPR004899 Pertactin, central region WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 Gene3D G3DSA:2.40.128.130 649 948 1.2E-45 T 28-03-2018 WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 SUPERFAMILY SSF103515 660 948 5.62E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 Pfam PF03797 Autotransporter beta-domain 687 928 1.9E-41 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS03705 8e3bd9a9fa463b6e02ad7ef0d2c2514a 948 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 507 948 2.4E-105 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS17955 0ee0e1ad54542c7a4dcd2d2cf33e8124 219 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 204 2.0E-93 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 WM46_RS17955 0ee0e1ad54542c7a4dcd2d2cf33e8124 219 SMART SM00882 5 198 8.0E-66 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS17955 0ee0e1ad54542c7a4dcd2d2cf33e8124 219 SUPERFAMILY SSF100950 2 214 1.1E-68 T 28-03-2018 WM46_RS17955 0ee0e1ad54542c7a4dcd2d2cf33e8124 219 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 43 51 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS17955 0ee0e1ad54542c7a4dcd2d2cf33e8124 219 Gene3D G3DSA:3.40.1080.10 2 210 2.8E-65 T 28-03-2018 WM46_RS17955 0ee0e1ad54542c7a4dcd2d2cf33e8124 219 Pfam PF01144 Coenzyme A transferase 5 193 3.8E-37 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS15900 eac929f85497f76c8751db47c65950e9 227 Gene3D G3DSA:3.40.190.10 62 181 2.5E-15 T 28-03-2018 WM46_RS15900 eac929f85497f76c8751db47c65950e9 227 SUPERFAMILY SSF53850 2 226 6.02E-32 T 28-03-2018 WM46_RS15900 eac929f85497f76c8751db47c65950e9 227 Pfam PF13531 Bacterial extracellular solute-binding protein 2 226 6.1E-33 T 28-03-2018 WM46_RS17125 9af9346cb411999b95d3c4555f410e0f 648 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 9 557 2.1E-171 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 WM46_RS17125 9af9346cb411999b95d3c4555f410e0f 648 Gene3D G3DSA:1.50.10.10 54 181 1.5E-10 T 28-03-2018 WM46_RS17125 9af9346cb411999b95d3c4555f410e0f 648 SUPERFAMILY SSF48208 13 423 9.87E-40 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS17125 9af9346cb411999b95d3c4555f410e0f 648 Gene3D G3DSA:1.50.10.20 182 344 3.5E-35 T 28-03-2018 WM46_RS03290 271118a95edd0a398af037aab69eaed3 134 Gene3D G3DSA:2.40.300.10 12 126 1.9E-34 T 28-03-2018 WM46_RS03290 271118a95edd0a398af037aab69eaed3 134 Pfam PF02924 Bacteriophage lambda head decoration protein D 31 116 2.5E-17 T 28-03-2018 IPR004195 Head decoration protein D GO:0019028 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.2E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 Gene3D G3DSA:1.10.10.10 3 90 9.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 SUPERFAMILY SSF46785 9 93 1.56E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 6.0E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 Gene3D G3DSA:3.40.190.10 99 189 5.7E-15 T 28-03-2018 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 Gene3D G3DSA:3.40.190.10 190 272 9.2E-18 T 28-03-2018 WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 Pfam PF03466 LysR substrate binding domain 95 301 1.2E-32 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS02500 87a683313506e4b6e03b4bf70c1cdde3 302 SUPERFAMILY SSF53850 96 301 2.44E-33 T 28-03-2018 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.5E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 Pfam PF00293 NUDIX domain 7 146 6.7E-27 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 Gene3D G3DSA:3.90.79.10 1 164 2.2E-35 T 28-03-2018 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 SUPERFAMILY SSF55811 5 160 5.42E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS24860 dff68a4c81e9f9fe37418a63306f44bb 176 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.946 T 28-03-2018 IPR022927 RNA pyrophosphohydrolase RppH WM46_RS06860 c164f772f9ff675fe8c8453d93ee2fa2 195 Gene3D G3DSA:3.30.1380.10 3 174 7.9E-50 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM46_RS06860 c164f772f9ff675fe8c8453d93ee2fa2 195 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 6 181 27.594 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 WM46_RS06860 c164f772f9ff675fe8c8453d93ee2fa2 195 PIRSF PIRSF026671 2 187 1.6E-55 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 WM46_RS06860 c164f772f9ff675fe8c8453d93ee2fa2 195 Pfam PF01427 D-ala-D-ala dipeptidase 6 186 3.1E-66 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 WM46_RS06860 c164f772f9ff675fe8c8453d93ee2fa2 195 SUPERFAMILY SSF55166 6 169 1.96E-55 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 WM46_RS09545 45d205b72e1fa91095d36f365ccd1d51 280 Pfam PF00892 EamA-like transporter family 4 131 2.0E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS09545 45d205b72e1fa91095d36f365ccd1d51 280 Pfam PF00892 EamA-like transporter family 142 271 6.6E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS09545 45d205b72e1fa91095d36f365ccd1d51 280 SUPERFAMILY SSF103481 175 276 4.32E-15 T 28-03-2018 WM46_RS09545 45d205b72e1fa91095d36f365ccd1d51 280 SUPERFAMILY SSF103481 38 135 2.22E-6 T 28-03-2018 WM46_RS18995 c18c87f307585d04129d9d20b0321a52 176 Gene3D G3DSA:1.20.120.290 31 111 7.8E-4 T 28-03-2018 WM46_RS18995 c18c87f307585d04129d9d20b0321a52 176 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 80 1.2E-31 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 WM46_RS18995 c18c87f307585d04129d9d20b0321a52 176 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 143 18.986 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 WM46_RS18995 c18c87f307585d04129d9d20b0321a52 176 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 2.1E-33 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 WM46_RS18995 c18c87f307585d04129d9d20b0321a52 176 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.1E-33 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 WM46_RS18995 c18c87f307585d04129d9d20b0321a52 176 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.1E-33 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 WM46_RS14300 55557f91017c2b3be58911d56028b9d3 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS14300 55557f91017c2b3be58911d56028b9d3 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 1.8E-9 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS14300 55557f91017c2b3be58911d56028b9d3 145 SUPERFAMILY SSF54523 7 113 2.83E-22 T 28-03-2018 WM46_RS14300 55557f91017c2b3be58911d56028b9d3 145 Pfam PF00114 Pilin (bacterial filament) 36 124 1.7E-4 T 28-03-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 WM46_RS14300 55557f91017c2b3be58911d56028b9d3 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 25 1.6E-10 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS14300 55557f91017c2b3be58911d56028b9d3 145 Gene3D G3DSA:3.30.700.10 7 139 7.0E-25 T 28-03-2018 WM46_RS05880 c764913ac1e17cda5051999c65503681 348 SUPERFAMILY SSF52096 239 298 1.46E-32 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS05880 c764913ac1e17cda5051999c65503681 348 SUPERFAMILY SSF52096 97 208 1.46E-32 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS05880 c764913ac1e17cda5051999c65503681 348 Gene3D G3DSA:3.90.226.10 23 305 7.4E-32 T 28-03-2018 WM46_RS05880 c764913ac1e17cda5051999c65503681 348 Pfam PF01343 Peptidase family S49 160 309 4.4E-48 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 WM46_RS05880 c764913ac1e17cda5051999c65503681 348 Pfam PF08496 Peptidase family S49 N-terminal 2 157 2.7E-61 T 28-03-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 WM46_RS07975 d02925c66b4954a7a431d1d117c5e133 480 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 2 451 1.4E-155 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 WM46_RS07975 d02925c66b4954a7a431d1d117c5e133 480 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 1 466 45.673 T 28-03-2018 IPR003846 Uncharacterised protein family UPF0061 WM46_RS12350 e97276770b0080e8bd5e9af528aedfa9 434 Gene3D G3DSA:3.40.1190.20 32 431 2.7E-42 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS12350 e97276770b0080e8bd5e9af528aedfa9 434 Pfam PF00294 pfkB family carbohydrate kinase 138 294 1.2E-9 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS12350 e97276770b0080e8bd5e9af528aedfa9 434 SUPERFAMILY SSF53613 36 305 3.27E-45 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS12350 e97276770b0080e8bd5e9af528aedfa9 434 SUPERFAMILY SSF53613 338 416 3.27E-45 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS12350 e97276770b0080e8bd5e9af528aedfa9 434 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 352 365 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 Gene3D G3DSA:3.40.309.10 260 456 1.4E-66 T 28-03-2018 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 TIGRFAM TIGR03374 ABALDH: 1-pyrroline dehydrogenase 2 473 0.0 T 28-03-2018 IPR017749 1-pyrroline dehydrogenase GO:0009447|GO:0019145|GO:0051287|GO:0055114 KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 Pfam PF00171 Aldehyde dehydrogenase family 12 470 3.6E-164 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 SUPERFAMILY SSF53720 2 473 1.44E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 Hamap MF_01275 Gamma-aminobutyraldehyde dehydrogenase [prr]. 1 474 82.101 T 28-03-2018 IPR017749 1-pyrroline dehydrogenase GO:0009447|GO:0019145|GO:0051287|GO:0055114 KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3 WM46_RS06575 6cb99f61f1af13fab7535183d7df3809 474 Gene3D G3DSA:3.40.605.10 1 259 1.3E-96 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 218 230 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 Gene3D G3DSA:3.40.1380.20 328 480 3.7E-41 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 SUPERFAMILY SSF50800 74 168 1.74E-24 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 250 274 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 275 299 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 300 318 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 223 249 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 190 204 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 319 335 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.0E-50 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 SUPERFAMILY SSF52935 329 479 3.01E-38 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 477 1.2E-28 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 Pfam PF00224 Pyruvate kinase, barrel domain 6 344 9.6E-131 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 479 1.6E-173 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 SUPERFAMILY SSF51621 3 78 1.99E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 SUPERFAMILY SSF51621 160 345 1.99E-86 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 Gene3D G3DSA:3.20.20.60 6 174 8.2E-35 T 28-03-2018 WM46_RS04335 2188f1a465d60b4d91e3d6531b89ca4f 480 Gene3D G3DSA:3.20.20.60 175 327 4.2E-54 T 28-03-2018 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 153 3.5E-62 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 159 36.195 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 155 2.0E-83 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 121 140 2.0E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 2.0E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 2.0E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 2.0E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 2.0E-50 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 Gene3D G3DSA:3.30.1360.80 3 161 1.4E-64 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 SUPERFAMILY SSF63411 4 162 4.3E-67 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS25585 14606b5d3f8051badbd98fd224ebb8ca 171 PIRSF PIRSF006160 1 162 2.2E-66 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 Gene3D G3DSA:1.10.8.50 1 66 4.2E-21 T 28-03-2018 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 Gene3D G3DSA:4.10.910.10 67 84 4.4E-18 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.431 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 PIRSF PIRSF002134 1 118 5.1E-42 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 9.9E-53 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 SUPERFAMILY SSF46946 2 114 1.68E-45 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 Gene3D G3DSA:4.10.910.10 85 118 1.9E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17435 8874cda1c5386fd24b4ad72051a69f70 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 9.4E-34 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Gene3D G3DSA:3.10.50.40 279 386 2.6E-31 T 28-03-2018 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 321 342 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 SUPERFAMILY SSF109998 25 200 6.87E-44 T 28-03-2018 IPR027304 Trigger factor/SurA domain WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 SUPERFAMILY SSF54534 283 385 6.48E-32 T 28-03-2018 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 SUPERFAMILY SSF54534 173 275 2.62E-28 T 28-03-2018 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Pfam PF09312 SurA N-terminal domain 25 142 1.1E-46 T 28-03-2018 IPR015391 SurA N-terminal WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Gene3D G3DSA:3.10.50.40 163 278 5.3E-24 T 28-03-2018 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Hamap MF_01183 Chaperone SurA [surA]. 9 428 34.283 T 28-03-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Gene3D G3DSA:1.10.4030.10 21 148 1.4E-25 T 28-03-2018 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Pfam PF00639 PPIC-type PPIASE domain 178 272 3.6E-21 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 WM46_RS14555 b086c87988e094c79ffed0cfc71a4a97 428 Pfam PF00639 PPIC-type PPIASE domain 289 380 3.7E-25 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 WM46_RS10680 5f23fda4176c1222c839a2de6358cec2 261 Gene3D G3DSA:1.10.12.10 217 261 1.5E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal WM46_RS10680 5f23fda4176c1222c839a2de6358cec2 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 WM46_RS10680 5f23fda4176c1222c839a2de6358cec2 261 SUPERFAMILY SSF52096 1 260 3.6E-60 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS10680 5f23fda4176c1222c839a2de6358cec2 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 1.9E-45 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 WM46_RS10680 5f23fda4176c1222c839a2de6358cec2 261 Gene3D G3DSA:3.90.226.10 5 216 4.9E-45 T 28-03-2018 WM46_RS09880 b4637bae623edfa6203ea2ca6b863cb7 586 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 59 391 1.8E-80 T 28-03-2018 IPR003776 YcaO-like domain WM46_RS09880 b4637bae623edfa6203ea2ca6b863cb7 586 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 11 404 1.6E-169 T 28-03-2018 IPR003776 YcaO-like domain WM46_RS08880 91f8a37a0e44a86afeff2734fe309260 191 Pfam PF04264 YceI-like domain 25 186 1.3E-43 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM46_RS08880 91f8a37a0e44a86afeff2734fe309260 191 Hamap MF_00780 Protein YceI [yceI]. 1 191 48.146 T 28-03-2018 IPR023480 Uncharacterised protein family UPF0312/YceI WM46_RS08880 91f8a37a0e44a86afeff2734fe309260 191 Gene3D G3DSA:2.40.128.110 23 191 1.1E-52 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM46_RS08880 91f8a37a0e44a86afeff2734fe309260 191 SMART SM00867 24 188 1.1E-73 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM46_RS08880 91f8a37a0e44a86afeff2734fe309260 191 SUPERFAMILY SSF101874 22 190 1.96E-57 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like WM46_RS20390 6de45743767d936cce605e920fb140e4 378 Gene3D G3DSA:2.40.50.100 62 155 2.9E-10 T 28-03-2018 WM46_RS20390 6de45743767d936cce605e920fb140e4 378 Pfam PF00529 HlyD membrane-fusion protein of T1SS 39 367 1.8E-12 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS20390 6de45743767d936cce605e920fb140e4 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 68 301 1.1E-9 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS20390 6de45743767d936cce605e920fb140e4 378 SUPERFAMILY SSF111369 144 165 7.06E-13 T 28-03-2018 WM46_RS20390 6de45743767d936cce605e920fb140e4 378 SUPERFAMILY SSF111369 60 115 7.06E-13 T 28-03-2018 WM46_RS20390 6de45743767d936cce605e920fb140e4 378 SUPERFAMILY SSF111369 198 305 7.06E-13 T 28-03-2018 WM46_RS20390 6de45743767d936cce605e920fb140e4 378 Gene3D G3DSA:1.20.1600.10 199 331 3.4E-9 T 28-03-2018 WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 SUPERFAMILY SSF46785 4 65 2.03E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 Gene3D G3DSA:1.10.10.10 6 55 3.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 Pfam PF01037 Lrp/AsnC ligand binding domain 72 136 1.8E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 SUPERFAMILY SSF54909 67 140 2.41E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 Gene3D G3DSA:3.30.70.920 56 143 5.1E-14 T 28-03-2018 WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 SMART SM00344 5 111 3.5E-27 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 7.5E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.0E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.0E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS05660 b77994ff734f243b82e8538da73e20ab 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.0E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS09465 3c2762abed42c6efc4cb19f4c210f014 85 Hamap MF_00827 UPF0386 protein YjhX [yjhX]. 1 85 29.265 T 28-03-2018 IPR018654 Putative toxin of bacterial toxin-antitoxin pair WM46_RS09465 3c2762abed42c6efc4cb19f4c210f014 85 Pfam PF09857 Putative toxin of bacterial toxin-antitoxin pair 1 85 9.9E-41 T 28-03-2018 IPR018654 Putative toxin of bacterial toxin-antitoxin pair WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 ProSitePatterns PS00163 Fumarate lyases signature. 314 323 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00145 Argininosuccinate lyase family signature 314 330 7.6E-5 T 28-03-2018 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00145 Argininosuccinate lyase family signature 131 153 7.6E-5 T 28-03-2018 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00145 Argininosuccinate lyase family signature 172 192 7.6E-5 T 28-03-2018 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 Pfam PF10415 Fumarase C C-terminus 405 457 8.5E-14 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 Pfam PF00206 Lyase 10 339 3.7E-83 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 2.4E-26 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 2.4E-26 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00149 Fumarate lyase superfamily signature 268 295 2.4E-26 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 PRINTS PR00149 Fumarate lyase superfamily signature 314 330 2.4E-26 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 Gene3D G3DSA:1.10.40.30 416 462 3.2E-15 T 28-03-2018 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 Gene3D G3DSA:1.10.275.10 1 136 1.7E-49 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 SUPERFAMILY SSF48557 1 457 1.73E-123 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS24545 a85d00f19d62e8bcdf83a513ac98936f 476 Gene3D G3DSA:1.20.200.10 137 415 1.2E-66 T 28-03-2018 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 22 231 1.5E-96 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Gene3D G3DSA:3.30.450.40 501 655 1.5E-5 T 28-03-2018 IPR029016 GAF domain-like WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 SUPERFAMILY SSF55874 720 880 1.44E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Gene3D G3DSA:3.30.565.10 715 890 8.3E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 SMART SM00387 774 884 6.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Pfam PF00512 His Kinase A (phospho-acceptor) domain 665 731 1.7E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 829 839 4.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 881 4.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 811 825 4.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 862 4.0E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Pfam PF13493 Domain of unknown function (DUF4118) 404 508 1.0E-28 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 SUPERFAMILY SSF52402 254 372 1.84E-7 T 28-03-2018 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Pfam PF13492 GAF domain 530 645 5.1E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 SUPERFAMILY SSF47384 656 732 1.08E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Gene3D G3DSA:1.10.287.130 656 714 5.5E-11 T 28-03-2018 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 SMART SM00388 664 731 1.5E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Gene3D G3DSA:3.40.50.620 228 373 5.6E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 778 882 6.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Gene3D G3DSA:3.40.50.300 22 148 3.0E-22 T 28-03-2018 WM46_RS11110 921a9a59aa195adb14f2c1babad6860b 895 Gene3D G3DSA:1.20.120.620 402 500 5.2E-26 T 28-03-2018 WM46_RS21380 00ba56d2577cc59e9b3a58d9d7a48c91 92 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 3 90 8.8E-37 T 28-03-2018 IPR014057 Addiction module antidote protein, HI1420 WM46_RS21380 00ba56d2577cc59e9b3a58d9d7a48c91 92 SUPERFAMILY SSF47413 27 88 3.99E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS21380 00ba56d2577cc59e9b3a58d9d7a48c91 92 Gene3D G3DSA:1.10.260.40 35 90 3.9E-4 T 28-03-2018 WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 SUPERFAMILY SSF53822 62 325 1.93E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 63 272 7.2E-11 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 SMART SM00354 2 75 8.5E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 Gene3D G3DSA:3.40.50.2300 61 168 1.2E-22 T 28-03-2018 WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 Gene3D G3DSA:3.40.50.2300 169 329 4.0E-24 T 28-03-2018 WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 Gene3D G3DSA:1.10.260.40 4 60 2.0E-12 T 28-03-2018 WM46_RS25025 905c5aea6f265d46814ed2c684cfdc92 332 SUPERFAMILY SSF47413 4 60 1.13E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 SUPERFAMILY SSF69737 72 138 4.71E-21 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 Gene3D G3DSA:3.30.70.790 72 152 9.3E-31 T 28-03-2018 WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 Gene3D G3DSA:2.60.260.20 1 71 2.5E-20 T 28-03-2018 WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 PIRSF PIRSF036402 3 152 4.2E-45 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 139 23.138 T 28-03-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 SUPERFAMILY SSF69287 1 69 3.66E-17 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 Pfam PF02814 UreE urease accessory protein, N-terminal domain 13 62 2.0E-13 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 SMART SM00988 1 64 1.9E-19 T 28-03-2018 IPR004029 UreE urease accessory, N-terminal WM46_RS16280 f4aceeebd4c9603fd6de1ba9b55ccdc4 152 Pfam PF05194 UreE urease accessory protein, C-terminal domain 72 152 1.1E-27 T 28-03-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 WM46_RS10020 f95761472aabc960a393e36bd436b240 106 SUPERFAMILY SSF54736 22 105 3.77E-33 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM46_RS10020 f95761472aabc960a393e36bd436b240 106 Gene3D G3DSA:3.30.1390.10 13 105 4.8E-37 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM46_RS10020 f95761472aabc960a393e36bd436b240 106 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 102 1.7E-33 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 WM46_RS10020 f95761472aabc960a393e36bd436b240 106 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 15 101 28.18 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Gene3D G3DSA:3.30.70.240 625 702 5.8E-29 T 28-03-2018 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Pfam PF03144 Elongation factor Tu domain 2 331 398 2.2E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Pfam PF14492 Elongation Factor G, domain II 411 485 1.1E-33 T 28-03-2018 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SUPERFAMILY SSF54211 486 610 7.59E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SMART SM00838 611 698 1.1E-49 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Gene3D G3DSA:3.30.230.10 501 624 4.8E-40 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Hamap MF_00054_B Elongation factor G [fusA]. 6 702 111.935 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SMART SM00889 487 609 3.0E-71 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Gene3D G3DSA:3.40.50.300 1 293 4.8E-58 T 28-03-2018 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Gene3D G3DSA:3.30.70.870 407 500 2.4E-36 T 28-03-2018 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Pfam PF00679 Elongation factor G C-terminus 611 696 2.8E-28 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Gene3D G3DSA:2.40.30.10 295 406 4.1E-30 T 28-03-2018 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 703 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Pfam PF03764 Elongation factor G, domain IV 486 609 9.6E-45 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 3.7E-67 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 187 4.8E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SUPERFAMILY SSF52540 6 288 1.07E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SUPERFAMILY SSF54980 611 700 7.19E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SUPERFAMILY SSF50447 271 411 2.14E-35 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS17580 75fe476e65976d70f7ad9a8853ea28da 704 SUPERFAMILY SSF54980 411 488 3.02E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 SUPERFAMILY SSF57783 4 100 3.23E-36 T 28-03-2018 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 SUPERFAMILY SSF56731 115 428 2.18E-115 T 28-03-2018 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Pfam PF01807 CHC2 zinc finger 7 100 2.8E-41 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 SUPERFAMILY SSF117023 447 579 2.62E-43 T 28-03-2018 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 PIRSF PIRSF002811 2 580 1.0E-146 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Pfam PF10410 DnaB-helicase binding domain of primase 369 424 3.4E-12 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Gene3D G3DSA:1.20.50.20 368 417 5.6E-21 T 28-03-2018 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Gene3D G3DSA:3.90.580.10 1 101 2.6E-35 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 SMART SM00766 450 575 1.9E-49 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Hamap MF_00974 DNA primase [dnaG]. 4 576 30.38 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 251 1.1E-42 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Gene3D G3DSA:3.40.1360.10 241 367 1.2E-32 T 28-03-2018 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 SMART SM00400 36 90 8.0E-39 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Gene3D G3DSA:1.10.860.10 434 581 1.1E-38 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Gene3D G3DSA:3.90.980.10 109 240 1.8E-45 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 5.7E-152 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Pfam PF08278 DNA primase DnaG DnaB-binding 451 574 9.7E-33 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 SMART SM00493 259 330 6.5E-21 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS16305 f4c37a0c8bd6cdf190e5b170bd9bc834 581 Pfam PF13155 Toprim-like 263 348 1.4E-14 T 28-03-2018 WM46_RS06610 ed19fe21364072459626b6cd30eac2e5 532 SUPERFAMILY SSF53850 27 523 1.05E-150 T 28-03-2018 WM46_RS06610 ed19fe21364072459626b6cd30eac2e5 532 Gene3D G3DSA:3.90.76.10 36 201 9.1E-35 T 28-03-2018 WM46_RS06610 ed19fe21364072459626b6cd30eac2e5 532 Gene3D G3DSA:3.40.190.10 202 297 6.4E-26 T 28-03-2018 WM46_RS06610 ed19fe21364072459626b6cd30eac2e5 532 PIRSF PIRSF002741 3 532 6.6E-112 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS06610 ed19fe21364072459626b6cd30eac2e5 532 Gene3D G3DSA:3.10.105.10 298 502 1.6E-65 T 28-03-2018 WM46_RS06610 ed19fe21364072459626b6cd30eac2e5 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 451 6.0E-98 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00086 502 543 2.4E-5 T 28-03-2018 IPR001610 PAC motif WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00086 629 671 0.0021 T 28-03-2018 IPR001610 PAC motif WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00086 375 417 4.9E-8 T 28-03-2018 IPR001610 PAC motif WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Gene3D G3DSA:3.20.20.450 847 1103 1.0E-23 T 28-03-2018 IPR001633 EAL domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Pfam PF05231 MASE1 20 294 5.7E-38 T 28-03-2018 IPR007895 MASE1 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Gene3D G3DSA:3.30.450.20 287 437 1.6E-24 T 28-03-2018 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Gene3D G3DSA:3.30.450.20 552 687 1.4E-20 T 28-03-2018 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 299 421 9.3E-29 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 676 1.1E-11 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SUPERFAMILY SSF55785 295 414 8.38E-20 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Pfam PF13426 PAS domain 314 415 1.6E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Gene3D G3DSA:3.30.70.270 688 846 2.3E-53 T 28-03-2018 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Pfam PF08448 PAS fold 561 672 2.3E-10 T 28-03-2018 IPR013656 PAS fold-4 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SUPERFAMILY SSF55073 687 845 6.12E-46 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 680 842 1.3E-37 T 28-03-2018 IPR000160 GGDEF domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00052 855 1099 7.2E-33 T 28-03-2018 IPR001633 EAL domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Gene3D G3DSA:3.30.450.20 485 551 0.064 T 28-03-2018 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00091 429 496 2.9 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00091 555 623 1.0E-5 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00091 302 368 2.5E-9 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Pfam PF00990 Diguanylate cyclase, GGDEF domain 682 838 1.1E-43 T 28-03-2018 IPR000160 GGDEF domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SUPERFAMILY SSF141868 894 1101 5.62E-21 T 28-03-2018 IPR001633 EAL domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Pfam PF08447 PAS fold 452 537 3.1E-9 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Gene3D G3DSA:3.30.450.20 439 484 1.8E-11 T 28-03-2018 WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SMART SM00267 671 843 3.5E-63 T 28-03-2018 IPR000160 GGDEF domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SUPERFAMILY SSF55785 438 545 9.25E-14 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 SUPERFAMILY SSF55785 541 669 9.77E-18 T 28-03-2018 IPR000014 PAS domain WM46_RS02760 d2879bdd1c40d56f5610adde56dc3f80 1109 Pfam PF00563 EAL domain 890 1092 4.1E-21 T 28-03-2018 IPR001633 EAL domain WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 Gene3D G3DSA:3.40.50.620 9 221 9.5E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 SUPERFAMILY SSF82829 228 313 2.2E-27 T 28-03-2018 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 Pfam PF01171 PP-loop family 15 192 1.0E-60 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 6 301 23.644 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 Pfam PF11734 TilS substrate C-terminal domain 357 428 3.7E-25 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 SUPERFAMILY SSF56037 319 418 6.8E-30 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 358 402 3.9E-16 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 SMART SM00977 357 428 5.9E-24 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 SUPERFAMILY SSF52402 5 227 1.06E-63 T 28-03-2018 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 15 197 2.5E-53 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM46_RS13880 51a53e1df7ef24624a8fe733ef9040fa 432 Pfam PF09179 TilS substrate binding domain 242 309 5.6E-21 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.3E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 SMART SM00862 145 216 1.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 Gene3D G3DSA:1.10.10.10 122 221 1.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 SUPERFAMILY SSF46894 119 216 3.68E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 SMART SM00448 1 112 8.4E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 Gene3D G3DSA:3.40.50.2300 1 121 4.6E-31 T 28-03-2018 WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 SUPERFAMILY SSF52172 1 118 4.41E-35 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS16060 46d029cfb8a4b04a491697afbabc4090 221 Pfam PF00072 Response regulator receiver domain 3 112 8.9E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS25510 9c4853c4df7044a661501bcce3c42fcd 375 Gene3D G3DSA:1.10.530.10 255 375 1.0E-32 T 28-03-2018 WM46_RS25510 9c4853c4df7044a661501bcce3c42fcd 375 Gene3D G3DSA:1.10.8.350 145 249 3.7E-36 T 28-03-2018 WM46_RS25510 9c4853c4df7044a661501bcce3c42fcd 375 Gene3D G3DSA:1.10.8.350 68 144 2.7E-9 T 28-03-2018 WM46_RS25510 9c4853c4df7044a661501bcce3c42fcd 375 SUPERFAMILY SSF53955 62 370 3.19E-100 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS25510 9c4853c4df7044a661501bcce3c42fcd 375 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 77 369 3.1E-128 T 28-03-2018 IPR011757 Lytic transglycosylase MltB WM46_RS25510 9c4853c4df7044a661501bcce3c42fcd 375 Pfam PF13406 Transglycosylase SLT domain 73 367 4.4E-92 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 497 7.0E-231 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 PIRSF PIRSF000538 4 502 1.8E-178 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 SUPERFAMILY SSF53067 256 497 1.35E-87 T 28-03-2018 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 60.192 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 Gene3D G3DSA:3.30.420.40 250 502 1.0E-79 T 28-03-2018 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 SUPERFAMILY SSF53067 5 256 5.87E-96 T 28-03-2018 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 Gene3D G3DSA:3.30.420.40 1 249 1.8E-88 T 28-03-2018 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 6.2E-94 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS18435 228197a9ddf4af902681cba5e511a0be 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 451 1.9E-61 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Gene3D G3DSA:2.60.260.20 253 363 5.6E-27 T 28-03-2018 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 SUPERFAMILY SSF57938 132 209 5.62E-24 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 347 1.7E-143 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Gene3D G3DSA:2.60.260.20 192 252 6.6E-19 T 28-03-2018 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 SMART SM00271 4 62 9.3E-31 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Pfam PF01556 DnaJ C terminal domain 119 331 1.8E-46 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Gene3D G3DSA:2.10.230.10 145 191 8.4E-15 T 28-03-2018 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Pfam PF00226 DnaJ domain 5 67 4.1E-28 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 28-03-2018 IPR018253 DnaJ domain, conserved site WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 SUPERFAMILY SSF49493 112 167 9.03E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 SUPERFAMILY SSF49493 211 260 9.03E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 SUPERFAMILY SSF46565 1 107 3.53E-36 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Pfam PF00684 DnaJ central domain 145 205 8.8E-16 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 SUPERFAMILY SSF49493 257 342 5.23E-21 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 42.838 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 Gene3D G3DSA:1.10.287.110 1 116 2.7E-37 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 PRINTS PR00625 DnaJ domain signature 25 40 2.1E-33 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 PRINTS PR00625 DnaJ domain signature 7 25 2.1E-33 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 PRINTS PR00625 DnaJ domain signature 42 62 2.1E-33 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14760 29f8375921d1a567dd7c06d809831c89 377 PRINTS PR00625 DnaJ domain signature 62 81 2.1E-33 T 28-03-2018 IPR001623 DnaJ domain WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 SUPERFAMILY SSF88723 4 159 3.92E-38 T 28-03-2018 IPR029060 PIN domain-like WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 Gene3D G3DSA:3.40.50.1010 3 173 7.8E-40 T 28-03-2018 IPR029060 PIN domain-like WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 160 249 1.4E-25 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 154 2.8E-28 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 SUPERFAMILY SSF47807 160 243 1.3E-23 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 Gene3D G3DSA:1.10.150.20 174 251 6.6E-24 T 28-03-2018 WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 Hamap MF_01192 Flap endonuclease Xni [xni]. 2 251 46.226 T 28-03-2018 IPR022895 Flap endonuclease Xni GO:0048256 WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 SMART SM00475 3 250 1.6E-106 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 WM46_RS25035 582d39e72d2bdc68489ad2438afea429 251 SMART SM00279 162 197 6.0E-11 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 Pfam PF06689 ClpX C4-type zinc finger 13 50 1.2E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 SUPERFAMILY SSF57716 13 48 5.84E-12 T 28-03-2018 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 415 53.604 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 2.8E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 Pfam PF07724 AAA domain (Cdc48 subfamily) 112 310 1.0E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 SMART SM00994 12 51 1.0E-24 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 Gene3D G3DSA:3.40.50.300 56 315 1.3E-68 T 28-03-2018 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 SMART SM01086 317 412 8.8E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 412 6.0E-216 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 SMART SM00382 111 264 9.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 SUPERFAMILY SSF52540 64 402 2.38E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12625 bc878b83831428964a01082a9e7ee88d 424 Gene3D G3DSA:1.10.8.60 317 408 2.7E-33 T 28-03-2018 WM46_RS25440 e7a576ef42225e844955821b692cbb05 484 Pfam PF00367 phosphotransferase system, EIIB 11 43 7.6E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS25440 e7a576ef42225e844955821b692cbb05 484 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS25440 e7a576ef42225e844955821b692cbb05 484 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 154 441 1.4E-87 T 28-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS25440 e7a576ef42225e844955821b692cbb05 484 SUPERFAMILY SSF55604 8 82 1.44E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS25440 e7a576ef42225e844955821b692cbb05 484 Gene3D G3DSA:3.30.1360.60 6 82 2.1E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS25440 e7a576ef42225e844955821b692cbb05 484 Pfam PF02378 Phosphotransferase system, EIIC 113 396 8.3E-43 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 SUPERFAMILY SSF52540 6 235 3.48E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 Gene3D G3DSA:3.40.50.300 1 252 1.3E-57 T 28-03-2018 WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 Gene3D G3DSA:1.20.1250.20 253 638 4.6E-7 T 28-03-2018 WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 Pfam PF02687 FtsX-like permease family 546 635 1.5E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 Pfam PF00005 ABC transporter 24 172 7.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 Pfam PF12704 MacB-like periplasmic core domain 270 482 1.5E-25 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS15580 8f0510d6841b617fc2d4af7f20b2d8b5 642 SMART SM00382 33 220 1.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 8.1E-62 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2 101 5.6E-39 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 SUPERFAMILY SSF55347 152 315 4.76E-67 T 28-03-2018 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 Gene3D G3DSA:3.40.50.720 1 161 2.9E-72 T 28-03-2018 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 SMART SM00846 2 152 7.4E-92 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 PIRSF PIRSF000149 1 336 1.5E-130 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.1E-33 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.1E-33 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 1.1E-33 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.1E-33 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.1E-33 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 326 4.1E-126 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 Gene3D G3DSA:3.30.360.10 162 316 8.1E-64 T 28-03-2018 WM46_RS05310 a64abb50bf1fed4db6499ae6fbcabefd 336 SUPERFAMILY SSF51735 2 168 2.48E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS06405 b892fe99ee4b68ce6e76f7ae3821a6c0 206 Gene3D G3DSA:2.60.130.10 2 206 1.6E-55 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 WM46_RS06405 b892fe99ee4b68ce6e76f7ae3821a6c0 206 Pfam PF00775 Dioxygenase 40 196 2.7E-19 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 WM46_RS06405 b892fe99ee4b68ce6e76f7ae3821a6c0 206 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 51 79 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 WM46_RS06405 b892fe99ee4b68ce6e76f7ae3821a6c0 206 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 8 206 7.1E-80 T 28-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 WM46_RS06405 b892fe99ee4b68ce6e76f7ae3821a6c0 206 SUPERFAMILY SSF49482 3 206 8.77E-65 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 SUPERFAMILY SSF53706 11 631 6.81E-162 T 28-03-2018 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Pfam PF00384 Molybdopterin oxidoreductase 53 514 2.1E-109 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 456 473 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Gene3D G3DSA:2.40.40.20 586 760 6.8E-30 T 28-03-2018 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 10 772 0.0 T 28-03-2018 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 SUPERFAMILY SSF50692 627 771 9.72E-39 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Gene3D G3DSA:3.40.228.10 148 407 3.1E-58 T 28-03-2018 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Gene3D G3DSA:3.90.55.10 4 90 4.6E-12 T 28-03-2018 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Gene3D G3DSA:3.90.55.10 490 564 1.8E-18 T 28-03-2018 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Gene3D G3DSA:3.40.228.10 408 489 3.2E-6 T 28-03-2018 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 Pfam PF01568 Molydopterin dinucleotide binding domain 633 737 1.2E-24 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS20550 2df117199b320bbb0c31b6e58e499e1c 774 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 672 699 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS03615 1f6b1900a648f8262a2aad84cef203de 225 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 211 5.4E-52 T 28-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 WM46_RS03615 1f6b1900a648f8262a2aad84cef203de 225 Pfam PF02361 Cobalt transport protein 10 221 8.9E-49 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component WM46_RS22795 ebbc69ae957a3675ae8283c3f7387b87 119 SUPERFAMILY SSF81343 1 118 5.23E-52 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22795 ebbc69ae957a3675ae8283c3f7387b87 119 PIRSF PIRSF000179 1 119 2.6E-52 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 WM46_RS22795 ebbc69ae957a3675ae8283c3f7387b87 119 Hamap MF_00709 Fumarate reductase subunit D [frdD]. 2 119 26.96 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 WM46_RS22795 ebbc69ae957a3675ae8283c3f7387b87 119 ProDom PD015693 FUMARATE MEMBRANE REDUCTASE D SUBUNIT INNER TRANSMEMBRANE HYDROPHOBIC REDUCTASE POLYPEPTIDE 1 119 1.0E-50 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 WM46_RS22795 ebbc69ae957a3675ae8283c3f7387b87 119 Pfam PF02313 Fumarate reductase subunit D 6 116 8.0E-51 T 28-03-2018 IPR003418 Fumarate reductase, subunit D GO:0006106|GO:0016020 WM46_RS22795 ebbc69ae957a3675ae8283c3f7387b87 119 Gene3D G3DSA:1.20.1300.10 1 119 3.2E-32 T 28-03-2018 WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 Gene3D G3DSA:3.40.640.10 123 371 2.7E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 SMART SM00345 7 66 1.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 Gene3D G3DSA:1.10.10.10 1 68 4.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 5.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 Pfam PF00155 Aminotransferase class I and II 106 459 5.1E-31 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 SUPERFAMILY SSF53383 81 466 2.06E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 Gene3D G3DSA:3.90.1150.10 372 469 1.1E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS23870 c9eab2668b8e1a9b8af9fdc7fddf4f3c 470 SUPERFAMILY SSF46785 1 70 6.09E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19450 e84b6a9570a3f80d5c97e5fec276c6a9 498 Hamap MF_01625 ATPase RavA [ravA]. 1 498 57.57 T 28-03-2018 IPR023671 ATPase RavA GO:0005737|GO:0016887 WM46_RS19450 e84b6a9570a3f80d5c97e5fec276c6a9 498 Pfam PF12592 Protein of unknown function (DUF3763) 444 497 4.6E-22 T 28-03-2018 IPR022547 ATPase, RavA, C-terminal GO:0016820 WM46_RS19450 e84b6a9570a3f80d5c97e5fec276c6a9 498 Gene3D G3DSA:3.40.50.300 7 220 9.2E-18 T 28-03-2018 WM46_RS19450 e84b6a9570a3f80d5c97e5fec276c6a9 498 SMART SM00382 38 187 1.8E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19450 e84b6a9570a3f80d5c97e5fec276c6a9 498 Pfam PF07728 AAA domain (dynein-related subfamily) 41 171 1.6E-25 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 WM46_RS19450 e84b6a9570a3f80d5c97e5fec276c6a9 498 SUPERFAMILY SSF52540 12 264 2.83E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 Gene3D G3DSA:1.10.8.10 1 84 4.6E-23 T 28-03-2018 WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 Pfam PF13847 Methyltransferase domain 108 262 1.1E-20 T 28-03-2018 IPR025714 Methyltransferase domain WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 275 46.185 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 271 1.3E-89 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 Gene3D G3DSA:3.40.50.150 85 275 3.5E-45 T 28-03-2018 WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 SUPERFAMILY SSF53335 4 273 1.61E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS05560 7704832afef02fd4efaaba8400036fef 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 1 274 5.2E-100 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 WM46_RS12260 34fbb0936df0b1c93b30f90c949dd086 228 Gene3D G3DSA:3.40.50.300 2 228 5.4E-60 T 28-03-2018 WM46_RS12260 34fbb0936df0b1c93b30f90c949dd086 228 SUPERFAMILY SSF52540 6 226 1.62E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12260 34fbb0936df0b1c93b30f90c949dd086 228 SMART SM00382 35 225 6.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS12260 34fbb0936df0b1c93b30f90c949dd086 228 Pfam PF00005 ABC transporter 26 174 5.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS12260 34fbb0936df0b1c93b30f90c949dd086 228 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS14175 69a1fb3bf7e818df742f6914beec1599 115 Pfam PF09691 Type II secretion system pilotin lipoprotein (PulS_OutS) 23 106 2.7E-9 T 28-03-2018 IPR019114 Chaperone lipoprotein, PulS/OutS-like WM46_RS14175 69a1fb3bf7e818df742f6914beec1599 115 ProDom PD074041 YACC EXPORTED PRECURSOR SIGNAL PERIPLASMIC Y0776 SIMILAR ECS0126 STY0189 ESCHERICHIA 1 115 8.0E-63 T 28-03-2018 WM46_RS04200 dc6532edf53c0724167dbe9c62ed6f9f 845 SUPERFAMILY SSF141729 63 174 8.76E-22 T 28-03-2018 WM46_RS04200 dc6532edf53c0724167dbe9c62ed6f9f 845 Pfam PF00577 Outer membrane usher protein 198 748 1.2E-175 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS04200 dc6532edf53c0724167dbe9c62ed6f9f 845 Pfam PF13953 PapC C-terminal domain 757 819 3.7E-19 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS04200 dc6532edf53c0724167dbe9c62ed6f9f 845 Pfam PF13954 PapC N-terminal domain 37 184 3.7E-29 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS04200 dc6532edf53c0724167dbe9c62ed6f9f 845 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 309 319 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS04275 da3a12e1507b1ea8fc13c21cc13d72d2 188 Gene3D G3DSA:3.40.50.850 2 188 7.6E-47 T 28-03-2018 WM46_RS04275 da3a12e1507b1ea8fc13c21cc13d72d2 188 Pfam PF00857 Isochorismatase family 9 183 6.5E-40 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS04275 da3a12e1507b1ea8fc13c21cc13d72d2 188 SUPERFAMILY SSF52499 3 188 1.7E-51 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS25185 c90f74dc05b49a814365de504a16fb52 284 Gene3D G3DSA:3.40.50.620 18 159 1.0E-4 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS25185 c90f74dc05b49a814365de504a16fb52 284 SUPERFAMILY SSF52467 163 279 1.91E-26 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS25185 c90f74dc05b49a814365de504a16fb52 284 Gene3D G3DSA:3.40.50.1220 160 284 7.3E-29 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS25185 c90f74dc05b49a814365de504a16fb52 284 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 167 245 1.1E-15 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 Pfam PF00455 DeoR C terminal sensor domain 85 236 2.2E-27 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 Gene3D G3DSA:3.40.50.1360 74 244 1.9E-14 T 28-03-2018 WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 SUPERFAMILY SSF100950 85 237 3.14E-11 T 28-03-2018 WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 Gene3D G3DSA:1.10.10.10 1 70 7.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 SMART SM01134 76 237 2.9E-35 T 28-03-2018 WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 Pfam PF08220 DeoR-like helix-turn-helix domain 8 56 8.1E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 SMART SM00420 8 59 7.5E-4 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS19815 1cafe870cc106cbd1bd26ed12d4af5db 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS02855 6409c69d7e0d18a54421e5750bff5696 408 Pfam PF13579 Glycosyl transferase 4-like domain 15 204 2.5E-27 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 WM46_RS02855 6409c69d7e0d18a54421e5750bff5696 408 TIGRFAM TIGR04007 wcaI: colanic acid biosynthesis glycosyltransferase WcaI 1 405 2.7E-266 T 28-03-2018 IPR023910 Colanic acid biosynthesis, glycosyl transferase, WcaI WM46_RS02855 6409c69d7e0d18a54421e5750bff5696 408 SUPERFAMILY SSF53756 1 310 1.41E-39 T 28-03-2018 WM46_RS02855 6409c69d7e0d18a54421e5750bff5696 408 Gene3D G3DSA:3.40.50.2000 219 392 5.3E-19 T 28-03-2018 WM46_RS02855 6409c69d7e0d18a54421e5750bff5696 408 Gene3D G3DSA:3.40.50.2000 14 218 1.0E-13 T 28-03-2018 WM46_RS02855 6409c69d7e0d18a54421e5750bff5696 408 Pfam PF00534 Glycosyl transferases group 1 221 389 3.8E-19 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS11395 b329b299205ea6c8a4bc6489b46f5547 370 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 WM46_RS11395 b329b299205ea6c8a4bc6489b46f5547 370 Pfam PF01098 Cell cycle protein 21 364 9.0E-125 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 WM46_RS11395 b329b299205ea6c8a4bc6489b46f5547 370 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 17 364 3.4E-137 T 28-03-2018 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 SMART SM00487 150 342 5.6E-20 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 SUPERFAMILY SSF52540 131 376 9.47E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 Gene3D G3DSA:3.40.50.300 484 958 4.1E-22 T 28-03-2018 WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 Pfam PF12137 RNA polymerase recycling family C-terminal 605 965 1.4E-157 T 28-03-2018 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 Pfam PF00176 SNF2 family N-terminal domain 174 441 1.7E-18 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 1 966 29.329 T 28-03-2018 IPR023949 RNA polymerase-associated protein RapA GO:0006355 WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 SMART SM00490 517 601 2.1E-17 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 Pfam PF00271 Helicase conserved C-terminal domain 495 601 6.7E-15 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 SUPERFAMILY SSF52540 480 644 4.61E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 SUPERFAMILY SSF52540 273 337 4.61E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14535 b52946bb4efceba71de0fc964e2ead0c 968 Gene3D G3DSA:3.40.50.10810 130 371 1.0E-26 T 28-03-2018 WM46_RS17340 f3bf0fee2e4abd481894524109710d4d 184 SUPERFAMILY SSF51161 5 176 2.08E-44 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS17340 f3bf0fee2e4abd481894524109710d4d 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 97 130 9.0E-8 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS17340 f3bf0fee2e4abd481894524109710d4d 184 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 46 0.0027 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS17340 f3bf0fee2e4abd481894524109710d4d 184 Gene3D G3DSA:2.160.10.10 2 184 4.1E-40 T 28-03-2018 WM46_RS16365 f2c07bae7473186beb83a027e601f37c 378 SUPERFAMILY SSF53335 192 373 1.79E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS16365 f2c07bae7473186beb83a027e601f37c 378 PIRSF PIRSF037565 1 374 1.1E-161 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS16365 f2c07bae7473186beb83a027e601f37c 378 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 302 308 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS16365 f2c07bae7473186beb83a027e601f37c 378 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 373 49.283 T 28-03-2018 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS16365 f2c07bae7473186beb83a027e601f37c 378 Gene3D G3DSA:3.40.50.150 183 378 7.2E-36 T 28-03-2018 WM46_RS16365 f2c07bae7473186beb83a027e601f37c 378 Pfam PF05175 Methyltransferase small domain 199 370 4.3E-58 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 WM46_RS03265 00d06015960d4d39d34e784f5a592450 708 Pfam PF05876 Phage terminase large subunit (GpA) 48 648 6.0E-145 T 28-03-2018 IPR008866 Bacteriophage lambda, GpA WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 247 289 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 SMART SM00342 210 293 5.5E-36 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 Pfam PF10114 Sensory domain found in PocR 7 166 2.5E-44 T 28-03-2018 IPR018771 PocR domain WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 277 293 1.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 277 1.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 Gene3D G3DSA:1.10.10.60 246 300 9.0E-15 T 28-03-2018 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 Gene3D G3DSA:1.10.10.60 107 245 5.1E-16 T 28-03-2018 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 SUPERFAMILY SSF46689 193 244 6.72E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 Pfam PF12833 Helix-turn-helix domain 217 294 8.7E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS03540 44a2da259124b21e0058ef637318cf08 305 SUPERFAMILY SSF46689 247 296 2.51E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 Gene3D G3DSA:3.30.930.10 126 469 2.3E-93 T 28-03-2018 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 469 45.678 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 3.9E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 400 3.9E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 PRINTS PR01042 Aspartyl-tRNA synthetase signature 424 438 3.9E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 3.9E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 Gene3D G3DSA:2.40.50.140 8 106 1.9E-17 T 28-03-2018 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 SUPERFAMILY SSF50249 16 101 8.78E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 469 1.1E-208 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 463 3.5E-82 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 Pfam PF01336 OB-fold nucleic acid binding domain 20 99 2.7E-12 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM46_RS09750 b6deb61d6864f55359eab2a78203a2e7 469 SUPERFAMILY SSF55681 96 468 6.77E-94 T 28-03-2018 WM46_RS05985 c5216b9314b2c6b1137c861806844876 185 Gene3D G3DSA:2.60.40.1090 29 185 6.8E-28 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS05985 c5216b9314b2c6b1137c861806844876 185 Pfam PF16970 Type-1 fimbrial protein, A 70 185 1.2E-12 T 28-03-2018 WM46_RS05985 c5216b9314b2c6b1137c861806844876 185 SUPERFAMILY SSF49401 30 185 3.38E-24 T 28-03-2018 IPR008966 Adhesion domain WM46_RS09130 de2592288b24408145fe695a31598def 1320 Gene3D G3DSA:1.10.1220.10 2 49 1.5E-5 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS09130 de2592288b24408145fe695a31598def 1320 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 882 889 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Gene3D G3DSA:3.40.309.10 902 1094 9.3E-46 T 28-03-2018 WM46_RS09130 de2592288b24408145fe695a31598def 1320 SUPERFAMILY SSF51730 262 618 1.14E-123 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like WM46_RS09130 de2592288b24408145fe695a31598def 1320 PIRSF PIRSF000197 74 1320 0.0 T 28-03-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Pfam PF01619 Proline dehydrogenase 270 569 5.9E-100 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 WM46_RS09130 de2592288b24408145fe695a31598def 1320 SUPERFAMILY SSF81935 88 261 7.59E-66 T 28-03-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 148 259 4.0E-46 T 28-03-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Gene3D G3DSA:3.20.20.220 178 610 1.3E-110 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like WM46_RS09130 de2592288b24408145fe695a31598def 1320 SUPERFAMILY SSF53720 657 1110 1.26E-123 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Pfam PF00171 Aldehyde dehydrogenase family 659 1105 7.0E-112 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS09130 de2592288b24408145fe695a31598def 1320 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 611 1112 3.5E-261 T 28-03-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM46_RS09130 de2592288b24408145fe695a31598def 1320 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 910 921 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Gene3D G3DSA:1.20.5.550 89 137 3.1E-17 T 28-03-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 WM46_RS09130 de2592288b24408145fe695a31598def 1320 Gene3D G3DSA:3.40.605.10 650 901 7.2E-71 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS09130 de2592288b24408145fe695a31598def 1320 SUPERFAMILY SSF47598 3 45 1.56E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 PIRSF PIRSF000498 1 212 1.5E-75 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 SUPERFAMILY SSF63380 1 93 1.7E-26 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 SUPERFAMILY SSF63380 94 200 8.08E-32 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 Gene3D G3DSA:2.40.30.20 1 89 5.1E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 1.8E-87 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 Pfam PF00677 Lumazine binding domain 3 87 2.3E-22 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 Pfam PF00677 Lumazine binding domain 100 185 1.3E-22 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS07645 cbce56303823886be4ba3e051a72c86a 213 Gene3D G3DSA:2.40.30.20 94 192 2.8E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19955 414926901adf0834b5327b6062834ddf 369 Pfam PF03841 L-seryl-tRNA selenium transferase 14 267 3.7E-18 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 WM46_RS19955 414926901adf0834b5327b6062834ddf 369 Gene3D G3DSA:3.40.640.10 30 274 9.1E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS19955 414926901adf0834b5327b6062834ddf 369 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 5 363 2.3E-159 T 28-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 WM46_RS19955 414926901adf0834b5327b6062834ddf 369 SUPERFAMILY SSF53383 12 365 7.57E-34 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Gene3D G3DSA:3.30.360.10 636 794 1.0E-53 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Pfam PF00696 Amino acid kinase family 2 284 2.5E-45 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS14810 93bb2546561615749324d4bb561681f2 820 PIRSF PIRSF000727 1 818 0.0 T 28-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 1.8E-150 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 660 682 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 SUPERFAMILY SSF55021 303 381 3.84E-23 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Pfam PF01842 ACT domain 324 376 1.9E-9 T 28-03-2018 IPR002912 ACT domain WM46_RS14810 93bb2546561615749324d4bb561681f2 820 SUPERFAMILY SSF55347 614 798 9.81E-52 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 SUPERFAMILY SSF53633 1 296 3.7E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 605 6.2E-32 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Gene3D G3DSA:3.40.1160.10 1 289 3.4E-63 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Pfam PF13840 ACT domain 393 453 5.5E-9 T 28-03-2018 IPR027795 GATS-like ACT domain WM46_RS14810 93bb2546561615749324d4bb561681f2 820 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Gene3D G3DSA:3.30.70.260 385 464 4.2E-19 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Gene3D G3DSA:3.30.70.260 290 384 7.7E-26 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 SUPERFAMILY SSF51735 464 636 2.17E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Pfam PF00742 Homoserine dehydrogenase 614 811 5.4E-47 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 Gene3D G3DSA:3.40.50.720 465 635 1.9E-29 T 28-03-2018 WM46_RS14810 93bb2546561615749324d4bb561681f2 820 SUPERFAMILY SSF55021 383 476 2.32E-22 T 28-03-2018 WM46_RS20400 c2427bfdbc368c5f1ec57541027b7e98 246 Pfam PF06629 MltA-interacting protein MipA 26 246 6.0E-51 T 28-03-2018 IPR010583 MltA-interacting MipA WM46_RS20400 c2427bfdbc368c5f1ec57541027b7e98 246 Gene3D G3DSA:2.40.160.20 6 246 2.1E-10 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS20400 c2427bfdbc368c5f1ec57541027b7e98 246 SUPERFAMILY SSF56925 98 246 3.61E-5 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 81 94 - T 28-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 Pfam PF17284 Spermidine synthase tetramerisation domain 6 57 4.9E-21 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 TIGRFAM TIGR00417 speE: spermidine synthase 7 278 2.1E-124 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 Gene3D G3DSA:3.40.50.150 57 288 3.5E-44 T 28-03-2018 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 Pfam PF01564 Spermine/spermidine synthase domain 60 239 1.7E-67 T 28-03-2018 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 SUPERFAMILY SSF53335 7 283 1.49E-89 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS14180 34c181c8c8467519886536e42e135d01 288 Gene3D G3DSA:2.30.140.10 1 54 3.3E-17 T 28-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM46_RS14180 34c181c8c8467519886536e42e135d01 288 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 6 284 39.114 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 439 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 478 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 453 1.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 SMART SM00387 388 498 9.5E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 SUPERFAMILY SSF47384 265 344 1.31E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 Gene3D G3DSA:1.10.287.130 271 339 1.9E-18 T 28-03-2018 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 497 4.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 281 343 1.4E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 SUPERFAMILY SSF55874 337 496 5.63E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 SMART SM00388 280 347 6.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18705 0719fb0960d923c92b446ba359c12096 498 Gene3D G3DSA:3.30.565.10 340 497 5.7E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 Pfam PF07883 Cupin domain 30 90 1.3E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 Gene3D G3DSA:2.60.120.10 7 97 2.1E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 Gene3D G3DSA:3.90.1240.10 98 293 1.7E-28 T 28-03-2018 WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 SUPERFAMILY SSF46689 181 230 1.57E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 SMART SM00342 196 279 4.1E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 SUPERFAMILY SSF51182 17 94 2.1E-11 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 SUPERFAMILY SSF46689 232 283 1.79E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS07925 b65b5882d3f9ffcc3c6e428ac2bd771b 296 Pfam PF12833 Helix-turn-helix domain 202 281 2.6E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS12610 af18bedc616c966159494a45323494b1 624 Pfam PF13145 PPIC-type PPIASE domain 247 369 2.5E-22 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 WM46_RS12610 af18bedc616c966159494a45323494b1 624 SUPERFAMILY SSF109998 203 240 8.11E-38 T 28-03-2018 IPR027304 Trigger factor/SurA domain WM46_RS12610 af18bedc616c966159494a45323494b1 624 SUPERFAMILY SSF109998 39 169 8.11E-38 T 28-03-2018 IPR027304 Trigger factor/SurA domain WM46_RS12610 af18bedc616c966159494a45323494b1 624 Pfam PF13624 SurA N-terminal domain 1 165 4.4E-54 T 28-03-2018 WM46_RS12610 af18bedc616c966159494a45323494b1 624 Gene3D G3DSA:3.10.50.40 230 381 9.2E-33 T 28-03-2018 WM46_RS12610 af18bedc616c966159494a45323494b1 624 Gene3D G3DSA:3.10.50.40 382 496 9.1E-8 T 28-03-2018 WM46_RS12610 af18bedc616c966159494a45323494b1 624 SUPERFAMILY SSF54534 225 355 4.51E-22 T 28-03-2018 WM46_RS12610 af18bedc616c966159494a45323494b1 624 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 295 316 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM46_RS12610 af18bedc616c966159494a45323494b1 624 Gene3D G3DSA:1.10.4030.10 177 229 0.0014 T 28-03-2018 WM46_RS12610 af18bedc616c966159494a45323494b1 624 Gene3D G3DSA:1.10.4030.10 38 170 8.5E-25 T 28-03-2018 WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 SUPERFAMILY SSF52540 7 201 2.45E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 SUPERFAMILY SSF52317 256 455 1.95E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 194 3.9E-22 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 5 445 42.741 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 444 6.1E-40 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 Gene3D G3DSA:3.40.50.300 3 196 4.0E-38 T 28-03-2018 WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 Gene3D G3DSA:3.40.50.880 197 440 4.0E-20 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS03545 a8f615c5ceb2341545ab718e34acf8a3 459 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 9 453 2.4E-135 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 WM46_RS12655 efc2e55b93f18e11ac74ebf880d40ebd 491 SUPERFAMILY SSF103473 13 404 5.23E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS12655 efc2e55b93f18e11ac74ebf880d40ebd 491 Pfam PF07690 Major Facilitator Superfamily 18 366 5.1E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS12655 efc2e55b93f18e11ac74ebf880d40ebd 491 Gene3D G3DSA:1.20.1250.20 1 200 2.1E-20 T 28-03-2018 WM46_RS12655 efc2e55b93f18e11ac74ebf880d40ebd 491 TIGRFAM TIGR00901 2A0125: AmpG-like permease 25 363 4.5E-124 T 28-03-2018 IPR004752 AmpG-like permease/Acetyl-coenzyme A transporter 1 GO:0016020 Reactome: R-HSA-425397 WM46_RS12655 efc2e55b93f18e11ac74ebf880d40ebd 491 Gene3D G3DSA:1.20.1250.20 214 414 9.2E-18 T 28-03-2018 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 8.6E-46 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.1E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.1E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.1E-25 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 Pfam PF00203 Ribosomal protein S19 3 83 8.5E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 Gene3D G3DSA:3.30.860.10 1 92 1.9E-40 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.549 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 PIRSF PIRSF002144 1 92 2.1E-31 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17525 75dc389130382ce3a8c6078ff4f868d1 92 SUPERFAMILY SSF54570 3 84 2.75E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Gene3D G3DSA:2.30.38.10 526 612 1.7E-14 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Pfam PF00501 AMP-binding enzyme 233 619 1.6E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Hamap MF_01162 Bifunctional protein Aas [aas]. 1 717 49.138 T 28-03-2018 IPR023775 Bifunctional protein Aas GO:0006631|GO:0008654|GO:0008779|GO:0008922 KEGG: 00071+6.2.1.20|KEGG: 00564+2.3.1.40|MetaCyc: PWY-6622|MetaCyc: PWY-7032 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Gene3D G3DSA:3.40.50.980 210 375 3.8E-20 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Gene3D G3DSA:3.30.300.30 613 717 3.2E-8 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Pfam PF01553 Acyltransferase 15 137 4.9E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Gene3D G3DSA:3.40.1130.10 4 209 9.0E-27 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 ProSitePatterns PS00455 Putative AMP-binding domain signature. 370 381 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 SUPERFAMILY SSF69593 5 170 2.62E-20 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 SUPERFAMILY SSF56801 205 713 5.49E-94 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 Gene3D G3DSA:3.40.50.980 376 525 3.7E-43 T 28-03-2018 WM46_RS24825 29a8254f958bc9b6d1d3768ac7ccaae6 719 SMART SM00563 30 140 4.4E-28 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS18115 7964865d9ea84da441fecf0e234c712a 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 253 1.9E-10 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal WM46_RS18115 7964865d9ea84da441fecf0e234c712a 255 Pfam PF00005 ABC transporter 21 181 4.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18115 7964865d9ea84da441fecf0e234c712a 255 SMART SM00382 30 230 2.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18115 7964865d9ea84da441fecf0e234c712a 255 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS18115 7964865d9ea84da441fecf0e234c712a 255 Gene3D G3DSA:3.40.50.300 1 253 7.0E-57 T 28-03-2018 WM46_RS18115 7964865d9ea84da441fecf0e234c712a 255 SUPERFAMILY SSF52540 4 253 2.4E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 Gene3D G3DSA:2.40.10.10 42 151 4.5E-32 T 28-03-2018 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 TIGRFAM TIGR02038 protease_degS: periplasmic serine peptidase DegS 2 352 3.6E-176 T 28-03-2018 IPR011783 Peptidase S1C, DegS GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 Gene3D G3DSA:2.30.42.10 259 355 3.8E-21 T 28-03-2018 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 SUPERFAMILY SSF50494 44 254 1.85E-61 T 28-03-2018 IPR009003 Peptidase S1, PA clan WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 SUPERFAMILY SSF50156 240 347 3.42E-20 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 SMART SM00228 257 339 6.3E-11 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 Pfam PF13365 Trypsin-like peptidase domain 80 215 3.0E-29 T 28-03-2018 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 Gene3D G3DSA:2.40.10.10 152 258 2.1E-31 T 28-03-2018 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 PRINTS PR00834 HtrA/DegQ protease family signature 297 309 1.5E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 PRINTS PR00834 HtrA/DegQ protease family signature 151 175 1.5E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 PRINTS PR00834 HtrA/DegQ protease family signature 208 225 1.5E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 PRINTS PR00834 HtrA/DegQ protease family signature 110 130 1.5E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 PRINTS PR00834 HtrA/DegQ protease family signature 186 203 1.5E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 PRINTS PR00834 HtrA/DegQ protease family signature 89 101 1.5E-47 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 WM46_RS17075 cdbff33a844e83027d81e32f85f1eb14 355 Pfam PF13180 PDZ domain 279 347 6.1E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 Hamap MF_00483 DNA replication terminus site-binding protein [tus]. 1 309 63.825 T 28-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 Gene3D G3DSA:3.30.54.10 264 308 1.9E-9 T 28-03-2018 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 Gene3D G3DSA:3.30.54.10 187 246 1.3E-30 T 28-03-2018 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 SUPERFAMILY SSF56596 5 308 7.98E-124 T 28-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 TIGRFAM TIGR02648 rep_term_tus: DNA replication terminus site-binding protein 10 308 1.4E-155 T 28-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 Gene3D G3DSA:3.50.14.10 7 186 4.3E-59 T 28-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 WM46_RS07370 c8ab17406148d57d44ca12ab92659de7 309 Pfam PF05472 DNA replication terminus site-binding protein (Ter protein) 9 306 2.7E-136 T 28-03-2018 IPR008865 DNA replication terminus site-binding protein GO:0003677|GO:0005737|GO:0006274 WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 Gene3D G3DSA:3.40.190.10 175 259 2.8E-25 T 28-03-2018 WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 SUPERFAMILY SSF46785 8 110 8.52E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 Gene3D G3DSA:3.40.190.10 85 174 5.7E-20 T 28-03-2018 WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 Gene3D G3DSA:1.10.10.10 4 84 4.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 SUPERFAMILY SSF53850 88 290 7.24E-45 T 28-03-2018 WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 Pfam PF03466 LysR substrate binding domain 88 289 3.4E-44 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS07855 2bb7e6d03286997c72323beedcaa2567 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 1.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 14 345 7.5E-62 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 Gene3D G3DSA:3.40.50.150 2 205 2.7E-65 T 28-03-2018 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 Pfam PF00145 C-5 cytosine-specific DNA methylase 12 348 2.6E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 SUPERFAMILY SSF53335 11 257 8.65E-83 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 SUPERFAMILY SSF53335 294 348 8.65E-83 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 73 85 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 158 171 1.1E-17 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 13 29 1.1E-17 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 112 126 1.1E-17 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS05340 9d582a51bc9e42fc645f98660f87a669 361 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 329 347 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 WM46_RS23960 43c39c713c07cb8eaf620d672d8b0baa 245 SUPERFAMILY SSF52540 64 222 1.98E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23960 43c39c713c07cb8eaf620d672d8b0baa 245 SMART SM00382 98 227 2.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS23960 43c39c713c07cb8eaf620d672d8b0baa 245 Pfam PF01695 IstB-like ATP binding protein 65 220 6.0E-19 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 WM46_RS23960 43c39c713c07cb8eaf620d672d8b0baa 245 Gene3D G3DSA:3.40.50.300 62 225 1.1E-19 T 28-03-2018 WM46_RS23960 43c39c713c07cb8eaf620d672d8b0baa 245 PIRSF PIRSF003073 1 245 1.2E-35 T 28-03-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein WM46_RS22070 204ddcf57892deb3523c560ff641e745 351 Pfam PF00419 Fimbrial protein 204 351 4.8E-22 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22070 204ddcf57892deb3523c560ff641e745 351 SUPERFAMILY SSF49401 211 351 1.74E-17 T 28-03-2018 IPR008966 Adhesion domain WM46_RS22070 204ddcf57892deb3523c560ff641e745 351 Gene3D G3DSA:2.60.40.1090 213 351 2.8E-16 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS15865 87ce82ad9263728ab0a6d8044a68869d 159 TIGRFAM TIGR00608 radc: DNA repair protein RadC 35 159 5.0E-44 T 28-03-2018 IPR001405 RadC protein WM46_RS15865 87ce82ad9263728ab0a6d8044a68869d 159 Pfam PF04002 RadC-like JAB domain 38 157 3.6E-42 T 28-03-2018 IPR025657 RadC-like JAB domain WM46_RS15865 87ce82ad9263728ab0a6d8044a68869d 159 Gene3D G3DSA:3.40.140.10 35 159 1.6E-43 T 28-03-2018 WM46_RS15865 87ce82ad9263728ab0a6d8044a68869d 159 SUPERFAMILY SSF102712 46 127 3.92E-6 T 28-03-2018 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 Gene3D G3DSA:3.40.50.720 1 127 4.0E-28 T 28-03-2018 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 Gene3D G3DSA:3.30.360.10 130 238 6.6E-35 T 28-03-2018 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 154 171 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 6 269 1.1E-111 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 SUPERFAMILY SSF51735 240 272 1.88E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 SUPERFAMILY SSF51735 5 130 1.88E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 PIRSF PIRSF000161 4 272 1.1E-90 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 129 6.0E-42 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 268 3.2E-42 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 269 35.277 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS14675 e09cac6242bd98dc93c60560ebb4b075 273 SUPERFAMILY SSF55347 131 240 3.05E-37 T 28-03-2018 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 Gene3D G3DSA:3.90.230.10 1 261 8.0E-89 T 28-03-2018 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 Pfam PF00557 Metallopeptidase family M24 12 242 4.7E-54 T 28-03-2018 IPR000994 Peptidase M24 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 250 5.2E-109 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 43.786 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 SUPERFAMILY SSF55920 3 255 1.96E-93 T 28-03-2018 IPR000994 Peptidase M24 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 1.2E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 1.2E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 1.2E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS13985 b8638c9e8a75fc944fb91d0bd1e25804 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 1.2E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 WM46_RS15490 2c01062cb522cb5acecc3d46ec163569 389 Gene3D G3DSA:1.20.1250.20 1 195 3.4E-11 T 28-03-2018 WM46_RS15490 2c01062cb522cb5acecc3d46ec163569 389 Pfam PF07690 Major Facilitator Superfamily 11 321 3.1E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS15490 2c01062cb522cb5acecc3d46ec163569 389 SUPERFAMILY SSF103473 6 386 6.8E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS15490 2c01062cb522cb5acecc3d46ec163569 389 Gene3D G3DSA:1.20.1250.20 198 388 2.0E-18 T 28-03-2018 WM46_RS16675 ea76bc4ccf7500680f5b50d03552f76a 191 Pfam PF04972 BON domain 124 188 1.3E-17 T 28-03-2018 IPR007055 BON domain WM46_RS16675 ea76bc4ccf7500680f5b50d03552f76a 191 Pfam PF04972 BON domain 46 113 1.3E-13 T 28-03-2018 IPR007055 BON domain WM46_RS16675 ea76bc4ccf7500680f5b50d03552f76a 191 SMART SM00749 51 114 1.0E-11 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM46_RS16675 ea76bc4ccf7500680f5b50d03552f76a 191 SMART SM00749 129 191 9.1E-7 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM46_RS04980 4c3289039ef90bdda103f6072fbd88aa 454 Pfam PF03315 Serine dehydratase beta chain 3 155 2.4E-56 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM46_RS04980 4c3289039ef90bdda103f6072fbd88aa 454 Pfam PF03313 Serine dehydratase alpha chain 185 448 2.5E-94 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit WM46_RS04980 4c3289039ef90bdda103f6072fbd88aa 454 SUPERFAMILY SSF143548 16 158 5.23E-46 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 WM46_RS04980 4c3289039ef90bdda103f6072fbd88aa 454 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 1.3E-229 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM46_RS04980 4c3289039ef90bdda103f6072fbd88aa 454 Gene3D G3DSA:1.10.4100.10 264 444 1.2E-33 T 28-03-2018 WM46_RS04980 4c3289039ef90bdda103f6072fbd88aa 454 Gene3D G3DSA:3.30.1330.90 10 158 3.6E-51 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 WM46_RS19100 67c16f9e20dc53c5ebeda74bf2cdbe01 238 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 200 6.8E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS19100 67c16f9e20dc53c5ebeda74bf2cdbe01 238 SUPERFAMILY SSF56784 9 238 8.52E-41 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19100 67c16f9e20dc53c5ebeda74bf2cdbe01 238 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 207 3.7E-14 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19100 67c16f9e20dc53c5ebeda74bf2cdbe01 238 Gene3D G3DSA:3.40.50.1000 1 238 1.3E-22 T 28-03-2018 IPR023214 HAD-like domain WM46_RS14150 e255c002ccf491f78eaf97110db86e16 178 Gene3D G3DSA:3.40.50.2020 1 175 3.6E-41 T 28-03-2018 WM46_RS14150 e255c002ccf491f78eaf97110db86e16 178 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 7 173 1.4E-73 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 WM46_RS14150 e255c002ccf491f78eaf97110db86e16 178 SUPERFAMILY SSF53271 3 174 2.62E-53 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS14150 e255c002ccf491f78eaf97110db86e16 178 Pfam PF00156 Phosphoribosyl transferase domain 13 160 3.6E-23 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM46_RS03590 a557962ad0c8b3067b0491ecde423b5c 261 Gene3D G3DSA:3.40.50.2300 85 261 1.1E-11 T 28-03-2018 WM46_RS03590 a557962ad0c8b3067b0491ecde423b5c 261 Gene3D G3DSA:3.40.50.720 4 84 0.0069 T 28-03-2018 WM46_RS03590 a557962ad0c8b3067b0491ecde423b5c 261 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 6 242 1.7E-71 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 WM46_RS03590 a557962ad0c8b3067b0491ecde423b5c 261 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 5 235 4.0E-51 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 74 93 8.2E-54 T 28-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 6 23 8.2E-54 T 28-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 23 44 8.2E-54 T 28-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 129 142 8.2E-54 T 28-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 PRINTS PR01404 DATP pyrophosphohydrolase signature 102 123 8.2E-54 T 28-03-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 Gene3D G3DSA:3.90.79.10 1 150 1.4E-28 T 28-03-2018 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 SUPERFAMILY SSF55811 5 143 5.82E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS04285 2e8448ca7605155f342b45e8ece3359d 150 Pfam PF00293 NUDIX domain 7 144 7.1E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 86 299 1.2E-83 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 SUPERFAMILY SSF53649 5 79 5.5E-74 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 SUPERFAMILY SSF53649 315 510 5.5E-74 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 511 8.6E-245 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 SUPERFAMILY SSF64158 79 310 1.83E-85 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 Gene3D G3DSA:3.40.1450.10 79 301 8.2E-97 T 28-03-2018 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 Gene3D G3DSA:3.40.720.10 302 512 8.5E-48 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 512 50.049 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 Pfam PF01676 Metalloenzyme superfamily 6 500 3.1E-83 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 WM46_RS20265 67b699b49e4b2bc742044f61463fb137 514 PIRSF PIRSF001492 1 514 1.4E-207 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS17270 23410c36c3c16759561c91cfaf1e7b6b 387 Pfam PF00529 HlyD membrane-fusion protein of T1SS 154 359 2.6E-12 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS17270 23410c36c3c16759561c91cfaf1e7b6b 387 SUPERFAMILY SSF111369 51 299 1.31E-88 T 28-03-2018 WM46_RS17270 23410c36c3c16759561c91cfaf1e7b6b 387 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 374 3.6E-86 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS17270 23410c36c3c16759561c91cfaf1e7b6b 387 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 292 3.1E-14 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS17270 23410c36c3c16759561c91cfaf1e7b6b 387 Gene3D G3DSA:1.20.1600.10 2 304 3.6E-33 T 28-03-2018 WM46_RS24640 5f40fad3d5cfd4260883132204034e6e 180 Pfam PF00419 Fimbrial protein 35 179 4.4E-19 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24640 5f40fad3d5cfd4260883132204034e6e 180 Gene3D G3DSA:2.60.40.1090 32 180 6.2E-35 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24640 5f40fad3d5cfd4260883132204034e6e 180 SUPERFAMILY SSF49401 33 180 6.46E-35 T 28-03-2018 IPR008966 Adhesion domain WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 Gene3D G3DSA:1.10.260.40 18 58 2.4E-18 T 28-03-2018 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.3E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 SMART SM00354 1 72 3.8E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 SUPERFAMILY SSF47413 1 58 4.79E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 Gene3D G3DSA:3.40.50.2300 174 344 6.9E-38 T 28-03-2018 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 Pfam PF13377 Periplasmic binding protein-like domain 175 343 1.0E-31 T 28-03-2018 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 Gene3D G3DSA:1.10.10.10 2 17 0.052 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 SUPERFAMILY SSF53822 61 343 2.16E-55 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS24455 3ff2fdd29858e1341cfdba043a0da8df 344 Gene3D G3DSA:3.40.50.2300 59 173 1.2E-26 T 28-03-2018 WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 SUPERFAMILY SSF54893 2 100 9.03E-35 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 147 2.5E-17 T 28-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 32.139 T 28-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 2.0E-39 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 Gene3D G3DSA:3.30.70.140 5 97 5.6E-34 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 152 1.2E-69 T 28-03-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 Gene3D G3DSA:2.30.30.20 102 150 5.7E-18 T 28-03-2018 WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 SUPERFAMILY SSF57825 102 150 1.16E-14 T 28-03-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal WM46_RS23310 23ed548ce9f0da034e75d17394983d21 153 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 96 1.1E-29 T 28-03-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal WM46_RS23235 e79e1ef7fde844d2d73604c4b0ddcf94 246 Gene3D G3DSA:3.20.20.70 4 245 2.7E-118 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS23235 e79e1ef7fde844d2d73604c4b0ddcf94 246 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 8 242 5.4E-123 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS23235 e79e1ef7fde844d2d73604c4b0ddcf94 246 SUPERFAMILY SSF51569 53 205 8.79E-8 T 28-03-2018 WM46_RS23235 e79e1ef7fde844d2d73604c4b0ddcf94 246 Pfam PF07071 KDGP aldolase 8 224 7.0E-111 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS18260 011bb574dbfabda630efde350e618317 83 SUPERFAMILY SSF47336 3 81 1.31E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS18260 011bb574dbfabda630efde350e618317 83 Gene3D G3DSA:1.10.1200.10 5 82 3.1E-17 T 28-03-2018 WM46_RS18260 011bb574dbfabda630efde350e618317 83 Pfam PF00550 Phosphopantetheine attachment site 10 73 1.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS18260 011bb574dbfabda630efde350e618317 83 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 13.639 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 Gene3D G3DSA:1.10.10.60 145 192 0.046 T 28-03-2018 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 SMART SM00342 162 244 8.4E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 Gene3D G3DSA:1.10.10.60 193 252 4.6E-12 T 28-03-2018 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 198 240 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 Pfam PF12833 Helix-turn-helix domain 169 244 4.4E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 244 2.7E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 213 228 2.7E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS21955 9856d2beb965a9d6f466feb2b50ce354 253 SUPERFAMILY SSF46689 197 247 9.56E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 Pfam PF00270 DEAD/DEAH box helicase 27 191 2.9E-42 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 Gene3D G3DSA:3.40.50.300 214 450 3.3E-42 T 28-03-2018 WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 Pfam PF00271 Helicase conserved C-terminal domain 230 336 1.8E-27 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 SMART SM00490 255 336 9.2E-29 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 SMART SM00487 22 219 4.9E-54 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 5 457 70.019 T 28-03-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 Pfam PF03880 DbpA RNA binding domain 384 454 8.6E-21 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 Gene3D G3DSA:3.40.50.300 8 211 4.8E-55 T 28-03-2018 WM46_RS06235 5a2a446d03a9c20ca27d9bf25263a8ec 457 SUPERFAMILY SSF52540 73 350 1.63E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 SUPERFAMILY SSF56672 366 474 5.23E-70 T 28-03-2018 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 SUPERFAMILY SSF56672 185 338 5.23E-70 T 28-03-2018 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 SUPERFAMILY SSF56672 515 685 5.23E-70 T 28-03-2018 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 Gene3D G3DSA:3.30.420.10 2 201 6.1E-15 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 SUPERFAMILY SSF53098 6 190 2.22E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 Gene3D G3DSA:1.10.150.20 392 618 1.9E-18 T 28-03-2018 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 SMART SM00482 369 652 8.0E-9 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS13600 2fe99dc247a22fee2dd52a4b1a6f8c17 688 Pfam PF00476 DNA polymerase family A 214 460 6.2E-10 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 SUPERFAMILY SSF46689 220 267 2.06E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 Pfam PF01965 DJ-1/PfpI family 2 179 6.0E-20 T 28-03-2018 IPR002818 DJ-1/PfpI WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 271 313 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 Gene3D G3DSA:1.10.10.60 236 271 1.1E-12 T 28-03-2018 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 Gene3D G3DSA:1.10.10.60 272 326 5.7E-12 T 28-03-2018 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 Gene3D G3DSA:3.40.50.880 1 235 2.1E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 Pfam PF12833 Helix-turn-helix domain 240 319 9.0E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 SUPERFAMILY SSF52317 1 199 7.94E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 SUPERFAMILY SSF46689 271 321 8.96E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05315 28efd33018c82d14c0f5cbff721cb114 326 SMART SM00342 234 317 7.0E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 15 260 8.0E-90 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 Gene3D G3DSA:3.40.1190.20 2 262 3.8E-52 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 SUPERFAMILY SSF53613 15 259 9.49E-60 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 93 110 3.9E-43 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 36 57 3.9E-43 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 67 75 3.9E-43 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 123 137 3.9E-43 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 167 184 3.9E-43 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 23 30 3.9E-43 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 PIRSF PIRSF000513 9 262 6.5E-95 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 Pfam PF02110 Hydroxyethylthiazole kinase family 15 259 2.1E-96 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02675 b9a2fc864454045217bf5c545c1687da 262 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 17 262 30.191 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS17540 af999efcbd0a2375432bf21906bd585c 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 13 198 5.6E-75 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17540 af999efcbd0a2375432bf21906bd585c 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 201 33.976 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17540 af999efcbd0a2375432bf21906bd585c 201 Gene3D G3DSA:3.40.1370.10 141 199 1.5E-11 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 WM46_RS17540 af999efcbd0a2375432bf21906bd585c 201 Gene3D G3DSA:3.40.1370.10 4 140 7.2E-48 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 WM46_RS17540 af999efcbd0a2375432bf21906bd585c 201 SUPERFAMILY SSF52166 10 200 7.06E-73 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 WM46_RS17540 af999efcbd0a2375432bf21906bd585c 201 Pfam PF00573 Ribosomal protein L4/L1 family 13 198 3.1E-64 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 447 456 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Gene3D G3DSA:1.20.5.170 181 220 1.3E-19 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 SMART SM00382 241 404 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Gene3D G3DSA:3.40.50.10660 101 179 4.9E-24 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 11 530 1.0E-251 T 28-03-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 SUPERFAMILY SSF52540 220 464 4.24E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 SUPERFAMILY SSF159800 15 197 4.05E-52 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 SUPERFAMILY SSF46689 447 531 1.46E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Pfam PF06506 Propionate catabolism activator 39 201 5.4E-50 T 28-03-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Gene3D G3DSA:3.40.50.300 221 402 7.7E-24 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Pfam PF00158 Sigma-54 interaction domain 222 396 1.4E-63 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 316 331 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Gene3D G3DSA:3.40.50.2300 2 100 2.4E-23 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Gene3D G3DSA:1.10.8.60 403 486 2.0E-14 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Gene3D G3DSA:1.10.10.60 498 531 9.2E-10 T 28-03-2018 WM46_RS13180 5afe006cedae2a3f045ac0dd1d5dc160 531 Pfam PF02954 Bacterial regulatory protein, Fis family 501 531 2.8E-9 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS12950 8856688a2870d270059aa0a42579a98b 225 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 5 223 8.0E-96 T 28-03-2018 IPR010843 Uncharacterised protein family AroM WM46_RS12950 8856688a2870d270059aa0a42579a98b 225 Pfam PF07302 AroM protein 5 224 4.6E-69 T 28-03-2018 IPR010843 Uncharacterised protein family AroM WM46_RS12950 8856688a2870d270059aa0a42579a98b 225 Gene3D G3DSA:3.40.50.1860 137 225 0.0024 T 28-03-2018 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 Gene3D G3DSA:3.30.200.20 1 93 4.7E-24 T 28-03-2018 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 SUPERFAMILY SSF56104 3 232 1.41E-75 T 28-03-2018 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 234 1.4E-85 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 Pfam PF01259 SAICAR synthetase 7 231 1.4E-58 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 234 28.687 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS00860 c877fac0712e1ab9aad33fa4851901b2 237 Gene3D G3DSA:3.30.470.20 94 220 5.8E-46 T 28-03-2018 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 Gene3D G3DSA:1.10.3860.10 1 408 8.8E-115 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 295 318 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 SUPERFAMILY SSF118215 9 401 1.44E-121 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 PRINTS PR00173 Glutamate-aspartate symporter signature 292 318 4.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 PRINTS PR00173 Glutamate-aspartate symporter signature 192 211 4.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 4.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 4.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 PRINTS PR00173 Glutamate-aspartate symporter signature 327 346 4.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 PRINTS PR00173 Glutamate-aspartate symporter signature 145 167 4.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 Pfam PF00375 Sodium:dicarboxylate symporter family 9 401 2.3E-111 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS20690 ccf8d81bdf6aac0fef0d74174a403889 428 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 2 428 39.106 T 28-03-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 WM46_RS10575 08f6ff9f1cd3309da293f89442e530a6 228 Pfam PF13500 AAA domain 3 208 7.3E-38 T 28-03-2018 WM46_RS10575 08f6ff9f1cd3309da293f89442e530a6 228 Gene3D G3DSA:3.40.50.300 1 216 1.7E-56 T 28-03-2018 WM46_RS10575 08f6ff9f1cd3309da293f89442e530a6 228 PIRSF PIRSF006755 1 228 6.2E-82 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM46_RS10575 08f6ff9f1cd3309da293f89442e530a6 228 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 176 8.3E-63 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM46_RS10575 08f6ff9f1cd3309da293f89442e530a6 228 SUPERFAMILY SSF52540 3 210 3.86E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10575 08f6ff9f1cd3309da293f89442e530a6 228 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 212 30.15 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM46_RS15410 f409bff30f2cb84a63413b964a275c0e 147 Pfam PF02472 Biopolymer transport protein ExbD/TolR 17 134 2.9E-28 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 WM46_RS14030 afeeb6b2002b3e128bf5478e96f9937c 207 Pfam PF03458 UPF0126 domain 92 163 2.8E-18 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 WM46_RS14030 afeeb6b2002b3e128bf5478e96f9937c 207 Pfam PF03458 UPF0126 domain 4 78 2.1E-23 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 WM46_RS23985 7386c51479639595711a0542800f49ce 291 SUPERFAMILY SSF51215 38 170 2.09E-10 T 28-03-2018 WM46_RS23985 7386c51479639595711a0542800f49ce 291 Gene3D G3DSA:2.60.120.280 20 174 1.5E-17 T 28-03-2018 WM46_RS23985 7386c51479639595711a0542800f49ce 291 Gene3D G3DSA:1.10.10.60 178 238 5.3E-6 T 28-03-2018 WM46_RS23985 7386c51479639595711a0542800f49ce 291 SMART SM00342 202 285 9.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS23985 7386c51479639595711a0542800f49ce 291 SUPERFAMILY SSF46689 240 286 1.12E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS23985 7386c51479639595711a0542800f49ce 291 Gene3D G3DSA:1.10.10.60 240 287 1.0E-10 T 28-03-2018 WM46_RS23985 7386c51479639595711a0542800f49ce 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 269 285 8.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS23985 7386c51479639595711a0542800f49ce 291 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 269 8.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS23985 7386c51479639595711a0542800f49ce 291 Pfam PF12833 Helix-turn-helix domain 208 286 5.4E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 Gene3D G3DSA:3.40.50.150 135 351 1.1E-59 T 28-03-2018 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 Gene3D G3DSA:3.30.70.1170 63 134 5.1E-21 T 28-03-2018 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 156 166 4.4E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 327 344 4.4E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 273 289 4.4E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 223 235 4.4E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 125 139 4.4E-28 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 75 344 7.7E-111 T 28-03-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 42 139 5.7E-28 T 28-03-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 455 504 3.3E-10 T 28-03-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 222 233 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 Hamap MF_01579 Ribosomal RNA small subunit methyltransferase F [rsmF]. 40 509 64.68 T 28-03-2018 IPR023545 rRNA small subunit methyltransferase F GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 SUPERFAMILY SSF53335 41 344 1.74E-67 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04855 896380fe5255ab7ecafc2b0fe64d5ca5 513 Pfam PF01189 16S rRNA methyltransferase RsmB/F 153 343 2.4E-45 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 58 77 3.7E-38 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 360 374 3.7E-38 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 345 359 3.7E-38 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 424 437 3.7E-38 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 286 308 3.7E-38 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 20 468 1.4E-171 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 SUPERFAMILY SSF56601 23 473 9.79E-99 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 Gene3D G3DSA:3.40.710.10 20 477 2.0E-38 T 28-03-2018 WM46_RS16835 c569bead6d40fd64074b5064cc3881bd 477 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 48 447 7.5E-180 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS16145 e153a5c1c09a4c46cb814ee071c562ca 386 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 384 2.5E-161 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain WM46_RS16145 e153a5c1c09a4c46cb814ee071c562ca 386 SUPERFAMILY SSF52440 174 279 3.74E-39 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS16145 e153a5c1c09a4c46cb814ee071c562ca 386 SUPERFAMILY SSF56059 1 168 9.71E-95 T 28-03-2018 WM46_RS16145 e153a5c1c09a4c46cb814ee071c562ca 386 SUPERFAMILY SSF56059 266 383 9.71E-95 T 28-03-2018 WM46_RS18940 faf9403db110ffbbe2c461b136f16bc9 181 SUPERFAMILY SSF52218 2 173 1.56E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS18940 faf9403db110ffbbe2c461b136f16bc9 181 Gene3D G3DSA:3.40.50.360 2 174 6.5E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS18940 faf9403db110ffbbe2c461b136f16bc9 181 Pfam PF12724 Flavodoxin domain 4 152 2.5E-50 T 28-03-2018 IPR026816 Flavodoxin domain WM46_RS18940 faf9403db110ffbbe2c461b136f16bc9 181 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 124 135 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 SUPERFAMILY SSF54862 36 210 1.88E-52 T 28-03-2018 WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 Gene3D G3DSA:3.30.70.20 24 49 0.0031 T 28-03-2018 WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 Gene3D G3DSA:3.30.70.20 144 211 1.2E-13 T 28-03-2018 WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 Gene3D G3DSA:3.30.70.20 107 143 1.6E-20 T 28-03-2018 WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 Gene3D G3DSA:3.30.70.20 50 106 1.5E-14 T 28-03-2018 WM46_RS07740 0acd47aeb710c67cf035af79fe4c5e0d 222 Pfam PF13247 4Fe-4S dicluster domain 85 179 4.2E-22 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 SUPERFAMILY SSF53720 3 480 1.44E-166 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 4 487 4.1E-222 T 28-03-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 Gene3D G3DSA:3.40.605.10 1 259 7.0E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 Gene3D G3DSA:3.40.309.10 260 460 1.3E-72 T 28-03-2018 WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 Pfam PF00171 Aldehyde dehydrogenase family 17 474 6.9E-171 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS13345 7d889bc59b1a50563cfc323060bbab27 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 346 368 0.0014 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 444 478 1.5E-4 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 630 670 7.6E-7 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 529 561 1.3E-4 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 568 606 1.3E-8 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 461 501 6.3E-7 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 589 620 3.1E-5 T 28-03-2018 IPR006530 YD repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1168 1245 5.1E-24 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF10908 Protein of unknown function (DUF2778) 1286 1382 4.4E-7 T 28-03-2018 IPR021225 Protein of unknown function DUF2778 WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 PRINTS PR00394 RHS protein signature 1097 1116 1.0E-43 T 28-03-2018 IPR001826 RHS protein WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 PRINTS PR00394 RHS protein signature 1190 1210 1.0E-43 T 28-03-2018 IPR001826 RHS protein WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 PRINTS PR00394 RHS protein signature 1166 1181 1.0E-43 T 28-03-2018 IPR001826 RHS protein WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 PRINTS PR00394 RHS protein signature 1213 1232 1.0E-43 T 28-03-2018 IPR001826 RHS protein WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 PRINTS PR00394 RHS protein signature 1135 1155 1.0E-43 T 28-03-2018 IPR001826 RHS protein WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF03527 RHS protein 1142 1177 2.1E-11 T 28-03-2018 IPR001826 RHS protein WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF05593 RHS Repeat 442 475 1.4E-7 T 28-03-2018 IPR031325 RHS repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF05593 RHS Repeat 610 645 6.9E-5 T 28-03-2018 IPR031325 RHS repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF05593 RHS Repeat 630 667 8.3E-7 T 28-03-2018 IPR031325 RHS repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF05593 RHS Repeat 937 980 1.3E-4 T 28-03-2018 IPR031325 RHS repeat WM46_RS20865 0adc0feb5141fe22cd0f7284a5bb89be 1390 Pfam PF05593 RHS Repeat 568 604 2.0E-8 T 28-03-2018 IPR031325 RHS repeat WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 Gene3D G3DSA:3.10.290.10 331 424 1.2E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 SMART SM00363 358 419 1.3E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 4 423 46.572 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 424 4.4E-148 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 SUPERFAMILY SSF55174 327 423 3.14E-20 T 28-03-2018 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 1.7E-32 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 188 210 1.7E-32 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 182 1.7E-32 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 221 233 1.7E-32 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 Pfam PF01479 S4 domain 359 403 4.8E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 SUPERFAMILY SSF52374 4 328 5.63E-110 T 28-03-2018 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 Gene3D G3DSA:1.10.240.10 228 330 1.5E-32 T 28-03-2018 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 Gene3D G3DSA:3.40.50.620 1 227 1.1E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS07485 430d5da0e0cc78276f63280e979b059f 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 328 9.5E-93 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 SUPERFAMILY SSF55604 401 474 1.15E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 378 460 4.5E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 Gene3D G3DSA:3.30.1360.60 399 474 1.1E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 52 331 3.7E-90 T 28-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 414 431 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 Pfam PF00367 phosphotransferase system, EIIB 405 436 1.5E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 475 3.4E-234 T 28-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 WM46_RS08640 49339ad2e0a8da00c1a6b37c0bc2a685 477 Pfam PF02378 Phosphotransferase system, EIIC 13 320 2.1E-84 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS03040 d062a74065c647c95158c144174099c5 299 Gene3D G3DSA:3.40.190.10 129 223 3.4E-23 T 28-03-2018 WM46_RS03040 d062a74065c647c95158c144174099c5 299 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 7 197 2.4E-58 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM46_RS03040 d062a74065c647c95158c144174099c5 299 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 200 298 8.1E-33 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM46_RS03040 d062a74065c647c95158c144174099c5 299 Gene3D G3DSA:3.40.190.10 1 128 2.5E-36 T 28-03-2018 WM46_RS03040 d062a74065c647c95158c144174099c5 299 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 156 177 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 WM46_RS03040 d062a74065c647c95158c144174099c5 299 Pfam PF01634 ATP phosphoribosyltransferase 54 219 3.0E-48 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM46_RS03040 d062a74065c647c95158c144174099c5 299 SUPERFAMILY SSF53850 6 224 1.94E-70 T 28-03-2018 WM46_RS03040 d062a74065c647c95158c144174099c5 299 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 6 299 36.215 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 WM46_RS03040 d062a74065c647c95158c144174099c5 299 Gene3D G3DSA:3.30.70.120 227 298 2.5E-25 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM46_RS03040 d062a74065c647c95158c144174099c5 299 Pfam PF08029 HisG, C-terminal domain 223 296 1.4E-24 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 WM46_RS03040 d062a74065c647c95158c144174099c5 299 SUPERFAMILY SSF54913 226 298 7.45E-22 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 319 3.5E-173 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 Gene3D G3DSA:3.90.226.10 9 315 1.3E-68 T 28-03-2018 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 SUPERFAMILY SSF52096 5 318 9.19E-104 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 319 50.647 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 91 102 3.2E-50 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 200 209 3.2E-50 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 156 169 3.2E-50 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 134 3.2E-50 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 172 185 3.2E-50 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 137 153 3.2E-50 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS13895 00de027da1b79c1b6923fd3fdb9a4ec8 319 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 151 3.5E-62 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 SUPERFAMILY SSF53671 4 334 7.33E-99 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 332 8.3E-132 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 9.5E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 297 320 9.5E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 9.5E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 277 9.5E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 330 9.3E-55 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 333 82.542 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 6.9E-46 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 4.1E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 311 322 4.1E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 4.1E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 4.1E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 4.1E-32 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 Gene3D G3DSA:3.40.50.1370 1 147 9.8E-54 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23340 24eef6bac962b42347e7a7b41822eeb4 338 Gene3D G3DSA:3.40.50.1370 148 319 5.0E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 SUPERFAMILY SSF81923 1 141 2.75E-58 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 533 551 1.5E-35 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 595 609 1.5E-35 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 1.5E-35 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 562 580 1.5E-35 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Gene3D G3DSA:3.40.50.300 165 350 2.1E-28 T 28-03-2018 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Gene3D G3DSA:1.10.1780.10 1 143 1.6E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 SUPERFAMILY SSF52540 169 426 1.72E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 653 733 4.6E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 518 536 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 734 0.0 T 28-03-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 SMART SM01086 653 744 5.3E-36 T 28-03-2018 IPR019489 Clp ATPase, C-terminal WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 SMART SM00382 206 351 1.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 SMART SM00382 487 654 2.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 SUPERFAMILY SSF52540 437 747 3.43E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Gene3D G3DSA:1.10.8.60 351 437 2.0E-27 T 28-03-2018 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Gene3D G3DSA:3.40.50.300 442 652 1.8E-41 T 28-03-2018 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Pfam PF07724 AAA domain (Cdc48 subfamily) 486 647 4.7E-47 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 342 5.0E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Gene3D G3DSA:1.10.8.60 653 758 3.2E-25 T 28-03-2018 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 7.9E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 WM46_RS10015 fec8c593e308de9883112f0e49f60a8e 758 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 302 314 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 Gene3D G3DSA:1.10.10.10 1 72 2.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 SMART SM00420 6 58 2.7E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 56 3.9E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 Pfam PF00455 DeoR C terminal sensor domain 74 230 6.0E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 SMART SM01134 71 232 8.2E-57 T 28-03-2018 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 Gene3D G3DSA:3.40.50.1360 73 241 9.7E-36 T 28-03-2018 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.8E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.8E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 SUPERFAMILY SSF100950 74 230 8.06E-26 T 28-03-2018 WM46_RS06705 1b409f900671bcab3d84a5ca0eecf6c0 251 SUPERFAMILY SSF46785 4 57 1.65E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 5.9E-57 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 5.9E-57 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 5.9E-57 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 5.9E-57 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 5.9E-57 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 5.9E-57 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 PIRSF PIRSF005419 7 692 1.3E-243 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 Pfam PF00771 FHIPEP family 31 680 1.6E-268 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 28-03-2018 IPR025505 FHIPEP conserved site WM46_RS04220 1d08c2986314fe8b00af113ebc6b3859 692 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 22 689 2.0E-283 T 28-03-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 WM46_RS23335 10171c8ac1bd35c98fe38d057d3817ff 359 SUPERFAMILY SSF51419 12 228 8.9E-25 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS23335 10171c8ac1bd35c98fe38d057d3817ff 359 Gene3D G3DSA:3.20.20.10 4 235 2.3E-25 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS23335 10171c8ac1bd35c98fe38d057d3817ff 359 Pfam PF01168 Alanine racemase, N-terminal domain 11 229 3.8E-20 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 SUPERFAMILY SSF53098 235 380 5.69E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 Pfam PF13936 Helix-turn-helix domain 61 102 2.3E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 Pfam PF00665 Integrase core domain 236 339 1.4E-15 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 Gene3D G3DSA:1.10.10.10 1 48 9.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 Gene3D G3DSA:1.10.10.10 131 237 0.25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 Gene3D G3DSA:3.30.420.10 238 386 6.2E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS05260 ebdbb716b944480eae3deb0af4272f74 389 Gene3D G3DSA:1.10.10.60 61 104 7.4E-11 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 887 5.2E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 SMART SM00824 Thioesterase 1070 1246 5.9E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:3.40.50.980 606 768 4.2E-40 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 SUPERFAMILY SSF52777 190 426 4.78E-33 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Pfam PF00501 AMP-binding enzyme 462 863 4.6E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:3.30.300.30 858 985 1.8E-29 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1001 1016 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 ProSitePatterns PS00455 Putative AMP-binding domain signature. 600 611 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:2.30.38.10 773 853 1.3E-21 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Pfam PF00550 Phosphopantetheine attachment site 980 1042 2.6E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:1.10.1200.10 986 1054 7.2E-16 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:3.30.559.10 3 209 4.0E-20 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:3.40.50.980 453 605 2.3E-43 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Pfam PF00975 Thioesterase domain 1068 1285 1.9E-46 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Gene3D G3DSA:3.40.50.1820 1055 1293 3.4E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 SUPERFAMILY SSF52777 9 183 8.0E-32 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 SUPERFAMILY SSF47336 971 1042 1.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 SUPERFAMILY SSF56801 423 989 9.03E-147 T 28-03-2018 WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 SUPERFAMILY SSF53474 1054 1292 6.31E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11625 c9a5532639e735eb25a0c7ab5c4726b2 1298 Pfam PF00668 Condensation domain 5 442 3.4E-97 T 28-03-2018 IPR001242 Condensation domain WM46_RS25030 5424f223c9d264970adf9d79dd9a164a 215 SMART SM01007 8 182 2.1E-69 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS25030 5424f223c9d264970adf9d79dd9a164a 215 TIGRFAM TIGR01086 fucA: L-fuculose phosphate aldolase 2 215 3.0E-127 T 28-03-2018 IPR004782 L-fucose phosphate aldolase GO:0006004|GO:0008270|GO:0008738 KEGG: 00051+4.1.2.17|MetaCyc: PWY-5197 WM46_RS25030 5424f223c9d264970adf9d79dd9a164a 215 Gene3D G3DSA:3.40.225.10 1 213 2.5E-60 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS25030 5424f223c9d264970adf9d79dd9a164a 215 SUPERFAMILY SSF53639 1 212 1.96E-68 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS25030 5424f223c9d264970adf9d79dd9a164a 215 Hamap MF_00987 L-fuculose phosphate aldolase [fucA]. 1 215 60.423 T 28-03-2018 IPR004782 L-fucose phosphate aldolase GO:0006004|GO:0008270|GO:0008738 KEGG: 00051+4.1.2.17|MetaCyc: PWY-5197 WM46_RS25030 5424f223c9d264970adf9d79dd9a164a 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 181 2.4E-49 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 SUPERFAMILY SSF100879 248 345 2.62E-6 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Pfam PF11798 IMS family HHH motif 171 199 1.2E-5 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Gene3D G3DSA:3.30.70.270 37 114 4.6E-13 T 28-03-2018 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Gene3D G3DSA:3.30.70.270 115 172 4.3E-11 T 28-03-2018 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Gene3D G3DSA:1.10.150.20 173 248 1.4E-14 T 28-03-2018 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Gene3D G3DSA:3.30.1490.100 249 362 2.8E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Pfam PF00817 impB/mucB/samB family 6 149 1.8E-33 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Pfam PF13438 Domain of unknown function (DUF4113) 370 420 4.3E-21 T 28-03-2018 IPR025188 Domain of unknown function DUF4113 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 SUPERFAMILY SSF56672 1 236 2.76E-65 T 28-03-2018 WM46_RS05065 87bd1d0ceadcffc7ab4ff477ab8dea3d 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 242 350 2.5E-14 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 Pfam PF00145 C-5 cytosine-specific DNA methylase 364 444 2.6E-10 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 193 1.4E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 SUPERFAMILY SSF53335 306 334 6.09E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 SUPERFAMILY SSF53335 378 447 6.09E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 SUPERFAMILY SSF53335 1 240 6.09E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 TIGRFAM TIGR01712 phage_N6A_met: phage N-6-adenine-methyltransferase 459 624 2.6E-46 T 28-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 Pfam PF05869 DNA N-6-adenine-methyltransferase (Dam) 460 630 3.5E-56 T 28-03-2018 IPR008593 DNA N-6-adenine-methyltransferase GO:0003677|GO:0009007|GO:0032775 WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 67 79 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 5 444 1.4E-38 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 Gene3D G3DSA:3.90.120.10 190 435 2.2E-22 T 28-03-2018 WM46_RS04470 ca50869f0094ee7c0cebb3aafcfcbd6d 636 Gene3D G3DSA:3.40.50.150 1 189 4.3E-40 T 28-03-2018 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 Gene3D G3DSA:2.60.40.1760 25 229 3.8E-23 T 28-03-2018 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 SUPERFAMILY SSF74650 63 222 5.65E-21 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 Gene3D G3DSA:3.20.20.80 230 604 3.3E-78 T 28-03-2018 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 Pfam PF01055 Glycosyl hydrolases family 31 230 664 8.0E-74 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 SUPERFAMILY SSF51011 585 663 6.04E-22 T 28-03-2018 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 Gene3D G3DSA:2.60.40.1180 605 664 1.1E-23 T 28-03-2018 WM46_RS18805 307806f45c3ba274c801bffb9cc45426 678 SUPERFAMILY SSF51445 236 583 2.34E-50 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 Gene3D G3DSA:3.30.70.120 1 108 1.2E-49 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.6E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 SUPERFAMILY SSF54913 1 112 9.21E-47 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 SMART SM00938 4 105 4.8E-68 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 PIRSF PIRSF039144 1 112 2.0E-57 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 PRINTS PR00340 P-II protein signature 2 17 4.1E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 PRINTS PR00340 P-II protein signature 23 41 4.1E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 PRINTS PR00340 P-II protein signature 52 75 4.1E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS00495 e3024e8b8a720dd17b7e4466e1e5a4ff 112 PRINTS PR00340 P-II protein signature 83 103 4.1E-44 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS09120 3454118d3191c95de528d1bee0c591ef 502 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS09120 3454118d3191c95de528d1bee0c591ef 502 Pfam PF00474 Sodium:solute symporter family 35 437 2.1E-146 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS09120 3454118d3191c95de528d1bee0c591ef 502 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 437 2.0E-131 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS09120 3454118d3191c95de528d1bee0c591ef 502 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 6 490 4.1E-232 T 28-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 WM46_RS09120 3454118d3191c95de528d1bee0c591ef 502 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 419 439 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS14545 d2351ad223959430a71c573dabab06da 271 Pfam PF05099 Tellurite resistance protein TerB 47 170 2.5E-9 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal WM46_RS14545 d2351ad223959430a71c573dabab06da 271 Gene3D G3DSA:1.10.287.110 180 269 1.0E-14 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14545 d2351ad223959430a71c573dabab06da 271 Hamap MF_01153 Co-chaperone protein DjlA [djlA]. 3 270 38.725 T 28-03-2018 IPR023749 Co-chaperone DjlA GO:0051087 WM46_RS14545 d2351ad223959430a71c573dabab06da 271 SMART SM00271 204 269 3.0E-16 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14545 d2351ad223959430a71c573dabab06da 271 Gene3D G3DSA:1.10.3680.10 41 178 8.9E-24 T 28-03-2018 IPR029024 TerB-like WM46_RS14545 d2351ad223959430a71c573dabab06da 271 Pfam PF00226 DnaJ domain 208 267 2.3E-10 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14545 d2351ad223959430a71c573dabab06da 271 SUPERFAMILY SSF46565 131 267 1.15E-30 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14545 d2351ad223959430a71c573dabab06da 271 PRINTS PR00625 DnaJ domain signature 207 225 5.9E-7 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14545 d2351ad223959430a71c573dabab06da 271 PRINTS PR00625 DnaJ domain signature 249 269 5.9E-7 T 28-03-2018 IPR001623 DnaJ domain WM46_RS14545 d2351ad223959430a71c573dabab06da 271 PRINTS PR00625 DnaJ domain signature 225 240 5.9E-7 T 28-03-2018 IPR001623 DnaJ domain WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 Pfam PF00448 SRP54-type protein, GTPase domain 289 489 2.5E-79 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 SMART SM00963 195 275 1.5E-24 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 Gene3D G3DSA:3.40.50.300 282 491 4.5E-41 T 28-03-2018 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 218 490 65.533 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 SUPERFAMILY SSF47364 190 269 1.09E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 Pfam PF02881 SRP54-type protein, helical bundle domain 206 271 5.0E-14 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 Gene3D G3DSA:1.20.120.140 182 273 3.7E-23 T 28-03-2018 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 463 476 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 SUPERFAMILY SSF52540 282 489 1.88E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 SMART SM00382 288 479 9.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 218 489 2.4E-116 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 WM46_RS18175 417b12b2aa7207c6e31b3be5bee65c75 493 SMART SM00962 289 490 5.6E-126 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 WM46_RS07125 7337e3d8197216d1c6556158bbc513c3 367 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 12 348 2.3E-13 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS07125 7337e3d8197216d1c6556158bbc513c3 367 Gene3D G3DSA:3.20.20.210 2 367 1.5E-102 T 28-03-2018 WM46_RS07125 7337e3d8197216d1c6556158bbc513c3 367 SUPERFAMILY SSF51726 11 367 6.54E-83 T 28-03-2018 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 Pfam PF13353 4Fe-4S single cluster domain 23 125 4.4E-7 T 28-03-2018 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 329 5.4E-109 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 Gene3D G3DSA:3.20.20.70 1 329 5.4E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 Pfam PF04055 Radical SAM superfamily 19 181 2.5E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 SMART SM00729 14 222 8.8E-6 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 329 37.81 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 312 2.1E-39 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 WM46_RS10560 c7f66db562fcfe3d32d5f37762498d42 329 SUPERFAMILY SSF102114 5 289 4.58E-71 T 28-03-2018 WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 45 292 5.4E-86 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 Pfam PF02355 Protein export membrane protein 118 301 2.1E-69 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 Pfam PF07549 SecD/SecF GG Motif 40 66 2.0E-11 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 PRINTS PR01755 Bacterial translocase SecF protein signature 160 174 1.5E-30 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 PRINTS PR01755 Bacterial translocase SecF protein signature 44 59 1.5E-30 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 PRINTS PR01755 Bacterial translocase SecF protein signature 208 226 1.5E-30 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 PRINTS PR01755 Bacterial translocase SecF protein signature 240 255 1.5E-30 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 126 289 1.2E-53 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 SUPERFAMILY SSF82866 83 303 3.79E-38 T 28-03-2018 WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 Gene3D G3DSA:1.20.1640.10 107 313 3.3E-31 T 28-03-2018 WM46_RS12805 d7ea8c6b771cce5edb3c6e71819e7c1f 323 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 17 303 27.869 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 11 28 - T 28-03-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 Gene3D G3DSA:3.10.129.10 1 134 3.7E-37 T 28-03-2018 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 Pfam PF03061 Thioesterase superfamily 20 103 1.4E-18 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 6 130 2.2E-51 T 28-03-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 125 1.3E-49 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 PIRSF PIRSF003230 1 134 1.0E-48 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM46_RS10825 8ce12a1993033f8cf54fae434cb228fe 134 SUPERFAMILY SSF54637 2 133 5.87E-40 T 28-03-2018 IPR029069 HotDog domain WM46_RS14560 60116c0d06c44ced0b95eb5e4873e300 329 Gene3D G3DSA:3.40.718.10 2 329 7.4E-132 T 28-03-2018 WM46_RS14560 60116c0d06c44ced0b95eb5e4873e300 329 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 3 325 35.654 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 WM46_RS14560 60116c0d06c44ced0b95eb5e4873e300 329 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 321 8.0E-108 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 WM46_RS14560 60116c0d06c44ced0b95eb5e4873e300 329 SUPERFAMILY SSF53659 5 327 1.31E-114 T 28-03-2018 WM46_RS14560 60116c0d06c44ced0b95eb5e4873e300 329 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 324 4.5E-129 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 WM46_RS07720 ae43f97082765222eb1f47c33506e7f9 259 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 80 1.4E-13 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS07720 ae43f97082765222eb1f47c33506e7f9 259 Gene3D G3DSA:1.10.3720.10 3 243 6.6E-31 T 28-03-2018 WM46_RS07720 ae43f97082765222eb1f47c33506e7f9 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 238 1.1E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07720 ae43f97082765222eb1f47c33506e7f9 259 SUPERFAMILY SSF161098 17 223 2.35E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10950 3b48b94de7acccc5b1f7444ad35410da 269 Gene3D G3DSA:3.20.20.70 1 269 6.1E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS10950 3b48b94de7acccc5b1f7444ad35410da 269 Pfam PF05853 beta-keto acid cleavage enzyme 20 264 2.7E-63 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 443 4.7E-196 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Gene3D G3DSA:3.40.120.10 155 268 1.2E-33 T 28-03-2018 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 5.7E-20 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 5.0E-14 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 5.0E-14 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 5.0E-14 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 SUPERFAMILY SSF55957 357 444 2.09E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 445 47.591 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 366 1.1E-32 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Gene3D G3DSA:3.30.310.50 374 445 5.4E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 136 7.3E-45 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 SUPERFAMILY SSF53738 2 181 2.63E-48 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 SUPERFAMILY SSF53738 156 256 9.03E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Gene3D G3DSA:3.40.120.10 269 373 1.9E-29 T 28-03-2018 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Gene3D G3DSA:3.40.120.10 3 154 1.1E-47 T 28-03-2018 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 442 5.4E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS16805 d51e47792b0507fbcb9cbc7c1f59c096 445 SUPERFAMILY SSF53738 258 365 2.08E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 241 261 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 150 178 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 PIRSF PIRSF000112 1 360 3.7E-97 T 28-03-2018 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 Gene3D G3DSA:3.40.50.1970 3 159 3.0E-28 T 28-03-2018 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 Gene3D G3DSA:1.20.1090.10 160 363 4.4E-42 T 28-03-2018 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 SUPERFAMILY SSF56796 3 356 5.1E-87 T 28-03-2018 WM46_RS20930 0f79d0c54d105c01b36adbe92e645b74 367 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 348 9.1E-63 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS00650 c6f4e5073c12d559d44241dc4dd8640e 66 SUPERFAMILY SSF140319 3 64 6.54E-27 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 WM46_RS00650 c6f4e5073c12d559d44241dc4dd8640e 66 Gene3D G3DSA:1.10.10.600 2 64 5.8E-34 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 WM46_RS00650 c6f4e5073c12d559d44241dc4dd8640e 66 PIRSF PIRSF039003 3 66 1.5E-32 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 WM46_RS00650 c6f4e5073c12d559d44241dc4dd8640e 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 4 66 3.0E-32 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 WM46_RS00650 c6f4e5073c12d559d44241dc4dd8640e 66 Pfam PF04384 Iron-sulphur cluster assembly 3 66 2.3E-32 T 28-03-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 Hamap MF_01253 Endonuclease 8 [nei]. 1 263 60.989 T 28-03-2018 IPR023713 Endonuclease VIII GO:0003684|GO:0004519|GO:0006284|GO:0008270 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 SMART SM00898 2 110 7.4E-13 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 127 205 7.8E-11 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 Gene3D G3DSA:3.20.190.10 2 120 2.0E-23 T 28-03-2018 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 ProSitePatterns PS01242 Zinc finger FPG-type signature. 238 262 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 SUPERFAMILY SSF57716 226 262 1.65E-11 T 28-03-2018 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 104 2.1E-10 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 SUPERFAMILY SSF81624 2 127 1.18E-24 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 SUPERFAMILY SSF46946 126 215 9.16E-18 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 Pfam PF06827 Zinc finger found in FPG and IleRS 235 263 6.8E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 Gene3D G3DSA:1.10.8.50 121 263 6.6E-37 T 28-03-2018 WM46_RS11030 80eed03d5c8277983bb79d090512b176 263 SMART SM01232 126 221 2.2E-16 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 SMART SM00283 265 512 1.8E-72 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 328 478 1.9E-42 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 170 1.6E-18 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 3.0E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 3.0E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 3.0E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 3.0E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 3.0E-55 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 SMART SM00304 212 264 5.5E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 SUPERFAMILY SSF58104 232 513 2.35E-66 T 28-03-2018 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 Gene3D G3DSA:1.10.287.950 320 516 8.3E-44 T 28-03-2018 WM46_RS16340 c68ecf1386c220307a3bf05b4e4550a0 521 Gene3D G3DSA:1.10.287.950 72 319 9.2E-18 T 28-03-2018 WM46_RS19080 a630549718a70e50fb9ece84a762e436 155 SUPERFAMILY SSF54637 12 154 6.9E-25 T 28-03-2018 IPR029069 HotDog domain WM46_RS19080 a630549718a70e50fb9ece84a762e436 155 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 25 153 1.5E-14 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 WM46_RS19080 a630549718a70e50fb9ece84a762e436 155 Gene3D G3DSA:3.10.129.10 7 154 3.0E-28 T 28-03-2018 WM46_RS19080 a630549718a70e50fb9ece84a762e436 155 Pfam PF03061 Thioesterase superfamily 57 145 2.2E-18 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM46_RS14725 cc22639c379bc1637b6f4246c17d6abb 388 Gene3D G3DSA:1.20.1530.10 2 386 4.1E-155 T 28-03-2018 IPR023171 Na/H antiporter domain WM46_RS14725 cc22639c379bc1637b6f4246c17d6abb 388 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 7 380 2.7E-194 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 WM46_RS14725 cc22639c379bc1637b6f4246c17d6abb 388 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 4 386 24.022 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 WM46_RS14725 cc22639c379bc1637b6f4246c17d6abb 388 Pfam PF06965 Na+/H+ antiporter 1 6 380 1.4E-150 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 WM46_RS08520 9f0fa057b050ad6dd83dff1b7ea91dbe 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 281 2.0E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08520 9f0fa057b050ad6dd83dff1b7ea91dbe 285 SUPERFAMILY SSF161098 6 274 1.31E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08520 9f0fa057b050ad6dd83dff1b7ea91dbe 285 Gene3D G3DSA:1.10.3720.10 9 284 2.5E-42 T 28-03-2018 WM46_RS24000 96281ada0c06983483d952462e97bbae 152 Gene3D G3DSA:3.90.960.10 1 150 9.9E-40 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS24000 96281ada0c06983483d952462e97bbae 152 Pfam PF04073 Aminoacyl-tRNA editing domain 25 139 1.8E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS24000 96281ada0c06983483d952462e97bbae 152 SUPERFAMILY SSF55826 4 152 6.41E-41 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS14330 085745c232fc6e63c3f01badf85df829 64 Gene3D G3DSA:3.30.50.10 2 60 5.5E-28 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 WM46_RS14330 085745c232fc6e63c3f01badf85df829 64 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 3 59 19.465 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 WM46_RS14330 085745c232fc6e63c3f01badf85df829 64 Pfam PF03884 DNA gyrase inhibitor YacG 7 57 5.9E-25 T 28-03-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 WM46_RS14330 085745c232fc6e63c3f01badf85df829 64 SUPERFAMILY SSF57716 2 62 1.21E-22 T 28-03-2018 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 SUPERFAMILY SSF100879 245 334 2.49E-5 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Pfam PF00817 impB/mucB/samB family 5 149 1.7E-30 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Pfam PF13438 Domain of unknown function (DUF4113) 369 418 5.2E-17 T 28-03-2018 IPR025188 Domain of unknown function DUF4113 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Gene3D G3DSA:3.30.70.270 37 114 1.9E-14 T 28-03-2018 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Gene3D G3DSA:3.30.70.270 115 172 3.9E-10 T 28-03-2018 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Gene3D G3DSA:1.10.150.20 173 245 4.8E-16 T 28-03-2018 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 240 354 4.1E-15 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 Gene3D G3DSA:3.30.1490.100 246 360 1.8E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS26245 52d4fae7bbba4d5549a957a6c3cf4df2 421 SUPERFAMILY SSF56672 1 236 2.67E-62 T 28-03-2018 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 SUPERFAMILY SSF52540 4 286 2.88E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 PRINTS PR00478 Phosphoribulokinase family signature 126 144 2.7E-29 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 PRINTS PR00478 Phosphoribulokinase family signature 182 205 2.7E-29 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 PRINTS PR00478 Phosphoribulokinase family signature 164 181 2.7E-29 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 PRINTS PR00478 Phosphoribulokinase family signature 12 29 2.7E-29 T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 1.4E-77 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 28-03-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS17665 9a00a4a1b90a7597d666fea8db4caed9 289 Gene3D G3DSA:3.40.50.300 1 289 6.4E-41 T 28-03-2018 WM46_RS01185 7038e6fb25a7dfe3b051ed612883e0af 418 SUPERFAMILY SSF103473 7 406 4.45E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS01185 7038e6fb25a7dfe3b051ed612883e0af 418 Pfam PF03825 Nucleoside H+ symporter 1 406 1.0E-182 T 28-03-2018 WM46_RS01185 7038e6fb25a7dfe3b051ed612883e0af 418 Gene3D G3DSA:1.20.1250.20 199 415 1.4E-24 T 28-03-2018 WM46_RS01185 7038e6fb25a7dfe3b051ed612883e0af 418 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 416 8.7E-213 T 28-03-2018 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 WM46_RS01185 7038e6fb25a7dfe3b051ed612883e0af 418 Gene3D G3DSA:1.20.1250.20 5 194 1.9E-11 T 28-03-2018 WM46_RS13130 07e28916792ea2c2b790d81c203fe5f8 258 SUPERFAMILY SSF56281 1 246 4.34E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS13130 07e28916792ea2c2b790d81c203fe5f8 258 Gene3D G3DSA:3.60.15.10 1 258 9.0E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS13130 07e28916792ea2c2b790d81c203fe5f8 258 Pfam PF12706 Beta-lactamase superfamily domain 20 221 6.9E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.2E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.2E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 SUPERFAMILY SSF47413 1 56 6.94E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 Gene3D G3DSA:3.40.50.2300 58 167 3.8E-22 T 28-03-2018 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.7E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 Gene3D G3DSA:1.10.260.40 2 57 4.9E-21 T 28-03-2018 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 Pfam PF13377 Periplasmic binding protein-like domain 168 329 3.8E-34 T 28-03-2018 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 Gene3D G3DSA:3.40.50.2300 168 331 4.3E-43 T 28-03-2018 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 SUPERFAMILY SSF53822 61 332 1.76E-78 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS09550 72ff1438c4abfd17009a4e1a3c5dd691 336 SMART SM00354 1 71 1.1E-29 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 SUPERFAMILY SSF46894 118 217 2.07E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 SMART SM00862 145 216 1.3E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 Gene3D G3DSA:1.10.10.10 120 223 3.0E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 SUPERFAMILY SSF52172 1 132 3.27E-36 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 SMART SM00448 1 112 6.2E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 Gene3D G3DSA:3.40.50.2300 1 119 3.3E-33 T 28-03-2018 WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.3E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS21940 794d4fbc7f21c3c73c690c85a72ae1d2 224 Pfam PF00072 Response regulator receiver domain 3 113 1.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 SUPERFAMILY SSF55681 8 292 6.84E-134 T 28-03-2018 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 293 62.701 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 4.6E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 4.6E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 4.6E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 4.6E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 4.6E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 4.6E-71 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 292 6.8E-150 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 Gene3D G3DSA:3.30.930.10 1 214 5.9E-87 T 28-03-2018 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 Gene3D G3DSA:1.20.58.180 216 294 2.1E-32 T 28-03-2018 WM46_RS20485 5b6dde0f4b6fecfe1c35572071cf7b20 303 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 301 1.2E-177 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 SMART SM00342 197 280 1.3E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 Pfam PF12833 Helix-turn-helix domain 208 282 1.3E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 5.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 5.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 SUPERFAMILY SSF46689 233 282 1.39E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 Gene3D G3DSA:1.10.10.60 234 285 9.4E-17 T 28-03-2018 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 Pfam PF02311 AraC-like ligand binding domain 37 162 9.3E-16 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 SUPERFAMILY SSF46689 181 231 9.86E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 SUPERFAMILY SSF51215 20 166 4.71E-21 T 28-03-2018 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 Gene3D G3DSA:2.60.120.280 9 168 1.7E-18 T 28-03-2018 WM46_RS09425 1a1d0b374eefde6cdb4f98176edbff38 286 Gene3D G3DSA:1.10.10.60 169 233 1.7E-8 T 28-03-2018 WM46_RS20000 a268b2dcac1356358b7883db0739bb64 300 Pfam PF00892 EamA-like transporter family 158 290 6.2E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS20000 a268b2dcac1356358b7883db0739bb64 300 Pfam PF00892 EamA-like transporter family 6 145 1.2E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS20000 a268b2dcac1356358b7883db0739bb64 300 SUPERFAMILY SSF103481 191 296 7.98E-13 T 28-03-2018 WM46_RS20000 a268b2dcac1356358b7883db0739bb64 300 SUPERFAMILY SSF103481 43 148 4.32E-7 T 28-03-2018 WM46_RS20000 a268b2dcac1356358b7883db0739bb64 300 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 18 287 4.8E-72 T 28-03-2018 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 Pfam PF04324 BFD-like [2Fe-2S] binding domain 432 484 6.5E-10 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 SUPERFAMILY SSF51905 9 322 2.16E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 Gene3D G3DSA:3.50.50.60 2 393 3.3E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 311 317 3.1E-23 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 9 21 3.1E-23 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 3.1E-23 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 3.1E-23 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 22 32 3.1E-23 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 82 94 3.1E-23 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 TIGRFAM TIGR03377 glycerol3P_GlpA: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit 10 538 8.5E-265 T 28-03-2018 IPR017752 Glycerol-3-phosphate dehydrogenase, GlpA subunit GO:0004368|GO:0005886|GO:0010181|GO:0046174|GO:0050660|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 Pfam PF01266 FAD dependent oxidoreductase 10 359 1.1E-52 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 14 31 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS01970 9d5d32c747c964bf1c575dac5aa31ef0 542 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 352 362 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 SMART SM00354 9 79 2.3E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 Gene3D G3DSA:3.40.50.2300 177 334 3.4E-34 T 28-03-2018 WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 70 323 9.5E-25 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 Gene3D G3DSA:1.10.260.40 11 65 2.5E-19 T 28-03-2018 WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 Gene3D G3DSA:3.40.50.2300 66 176 4.1E-24 T 28-03-2018 WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 SUPERFAMILY SSF47413 9 67 7.07E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 SUPERFAMILY SSF53822 66 318 1.36E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS06685 64cbb21349d037b8a01b0ef20c083d64 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 2.8E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS11130 84b4651dc2605fc96bf95777abcde689 439 PIRSF PIRSF006060 1 437 9.2E-49 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS11130 84b4651dc2605fc96bf95777abcde689 439 Hamap MF_02073 Putrescine transporter PotE [potE]. 9 436 36.375 T 28-03-2018 IPR027566 Putrescine transporter PotE GO:0015496|GO:0015822|GO:0015847 WM46_RS11130 84b4651dc2605fc96bf95777abcde689 439 Pfam PF13520 Amino acid permease 10 404 2.6E-47 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS11130 84b4651dc2605fc96bf95777abcde689 439 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 432 3.3E-152 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 WM46_RS11130 84b4651dc2605fc96bf95777abcde689 439 TIGRFAM TIGR04299 antiport_PotE: putrescine-ornithine antiporter 4 433 8.1E-253 T 28-03-2018 IPR027566 Putrescine transporter PotE GO:0015496|GO:0015822|GO:0015847 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 Gene3D G3DSA:1.10.10.10 161 230 4.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 Gene3D G3DSA:3.30.450.80 13 160 3.1E-20 T 28-03-2018 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 SUPERFAMILY SSF46894 161 228 1.09E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 4.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 4.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 4.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 Pfam PF03472 Autoinducer binding domain 18 150 2.8E-18 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 SMART SM00421 165 222 1.1E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 SUPERFAMILY SSF75516 15 157 1.57E-28 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain WM46_RS24565 115e856f9a385dcbff34281861684b1a 230 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 220 7.4E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 SUPERFAMILY SSF55326 7 161 8.07E-41 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 SUPERFAMILY SSF56042 164 340 6.28E-50 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 Pfam PF00586 AIR synthase related protein, N-terminal domain 50 157 1.1E-18 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 TIGRFAM TIGR00476 selD: selenide, water dikinase 7 313 1.2E-132 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 Hamap MF_00625 Selenide, water dikinase [selD]. 5 347 45.056 T 28-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 PIRSF PIRSF036407 1 346 1.2E-115 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 Gene3D G3DSA:3.90.650.10 164 347 2.2E-41 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 Gene3D G3DSA:3.30.1330.10 1 162 1.8E-37 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS08260 f9e0e118a35639854f9b0b73f175be3d 347 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 344 1.5E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 SUPERFAMILY SSF56300 30 332 4.79E-68 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 Pfam PF00149 Calcineurin-like phosphoesterase 32 261 7.2E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 SUPERFAMILY SSF55816 335 514 3.79E-44 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 Gene3D G3DSA:3.90.780.10 337 523 2.7E-44 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 Pfam PF02872 5'-nucleotidase, C-terminal domain 338 482 1.2E-34 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 Gene3D G3DSA:3.60.21.10 25 336 1.0E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 ProSitePatterns PS00786 5'-nucleotidase signature 2. 109 120 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 PRINTS PR01607 Apyrase family signature 244 267 7.0E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 PRINTS PR01607 Apyrase family signature 388 411 7.0E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 PRINTS PR01607 Apyrase family signature 458 477 7.0E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 PRINTS PR01607 Apyrase family signature 272 292 7.0E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS14750 9c26ed674e727b7a7b10b5a874f41f58 523 PRINTS PR01607 Apyrase family signature 29 47 7.0E-17 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 SUPERFAMILY SSF55120 69 235 9.66E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 Pfam PF01479 S4 domain 4 45 1.3E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 SUPERFAMILY SSF55174 5 98 8.83E-14 T 28-03-2018 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 Gene3D G3DSA:3.10.290.10 1 63 2.9E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 SMART SM00363 3 74 7.5E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 Pfam PF00849 RNA pseudouridylate synthase 69 199 1.2E-15 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 73 233 3.4E-64 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 Gene3D G3DSA:3.30.70.1560 151 219 2.4E-21 T 28-03-2018 WM46_RS05865 6d2e712a286e1c9216baf4f67009dc36 291 Gene3D G3DSA:3.30.70.580 64 150 7.4E-17 T 28-03-2018 WM46_RS18740 f3cd6b70d47dd3d30f2ee0a151f5d735 95 Gene3D G3DSA:3.30.2310.20 1 89 7.7E-4 T 28-03-2018 WM46_RS18740 f3cd6b70d47dd3d30f2ee0a151f5d735 95 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 2 90 7.6E-16 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family WM46_RS18740 f3cd6b70d47dd3d30f2ee0a151f5d735 95 PIRSF PIRSF029218 1 95 2.0E-31 T 28-03-2018 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 WM46_RS08710 31f4357b479cc2235ac7adb121eb61ec 194 Pfam PF02545 Maf-like protein 4 186 1.1E-46 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS08710 31f4357b479cc2235ac7adb121eb61ec 194 Gene3D G3DSA:3.90.950.10 2 194 8.0E-60 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS08710 31f4357b479cc2235ac7adb121eb61ec 194 PIRSF PIRSF006305 1 193 2.4E-43 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS08710 31f4357b479cc2235ac7adb121eb61ec 194 Hamap MF_00528 Septum formation protein Maf [maf]. 3 191 30.786 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS08710 31f4357b479cc2235ac7adb121eb61ec 194 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 185 4.6E-67 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS08710 31f4357b479cc2235ac7adb121eb61ec 194 SUPERFAMILY SSF52972 1 185 3.66E-60 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS07045 04d4af7fdcce45a0af985e286fbedc2b 308 SUPERFAMILY SSF56601 8 308 6.29E-113 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS07045 04d4af7fdcce45a0af985e286fbedc2b 308 TIGRFAM TIGR03814 Gln_ase: glutaminase A 10 308 7.5E-129 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 WM46_RS07045 04d4af7fdcce45a0af985e286fbedc2b 308 Pfam PF04960 Glutaminase 24 308 3.3E-111 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 WM46_RS07045 04d4af7fdcce45a0af985e286fbedc2b 308 Hamap MF_00313 Glutaminase [glsA]. 6 308 46.456 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 WM46_RS07045 04d4af7fdcce45a0af985e286fbedc2b 308 Gene3D G3DSA:3.40.710.10 3 308 8.8E-123 T 28-03-2018 WM46_RS25195 4dfa9af428c9fd36d3793346ff1071a8 86 Gene3D G3DSA:3.30.70.20 26 56 4.4E-4 T 28-03-2018 WM46_RS25195 4dfa9af428c9fd36d3793346ff1071a8 86 PIRSF PIRSF036548 4 86 3.5E-22 T 28-03-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 WM46_RS25195 4dfa9af428c9fd36d3793346ff1071a8 86 SUPERFAMILY SSF54862 32 85 1.78E-8 T 28-03-2018 WM46_RS25195 4dfa9af428c9fd36d3793346ff1071a8 86 Gene3D G3DSA:3.30.70.20 57 76 0.072 T 28-03-2018 WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 SUPERFAMILY SSF53474 2 248 2.27E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 3 248 1.3E-82 T 28-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 5.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 5.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 5.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 5.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 Gene3D G3DSA:3.40.50.1820 1 252 1.2E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06200 5c8880a57cd45b2708c9f09f810d2141 254 Pfam PF12697 Alpha/beta hydrolase family 18 243 9.5E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 SUPERFAMILY SSF53254 4 247 7.71E-77 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 125 1.5E-29 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 SMART SM00855 5 191 2.0E-26 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 PIRSF PIRSF000709 3 116 2.0E-8 T 28-03-2018 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 PIRSF PIRSF000709 170 238 0.018 T 28-03-2018 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 3 230 46.661 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 Gene3D G3DSA:3.40.50.1240 2 250 4.6E-66 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS10725 8f1d21c995f4c5a20d9912e8a324a289 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 5 248 1.0E-128 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 WM46_RS10910 8615b5820390b1518a3f47e0bc7b6dbe 200 PIRSF PIRSF015617 5 200 2.8E-66 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS10910 8615b5820390b1518a3f47e0bc7b6dbe 200 Gene3D G3DSA:3.40.50.300 10 200 7.6E-70 T 28-03-2018 WM46_RS10910 8615b5820390b1518a3f47e0bc7b6dbe 200 SUPERFAMILY SSF52540 11 200 2.06E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10910 8615b5820390b1518a3f47e0bc7b6dbe 200 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 200 9.9E-74 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS10910 8615b5820390b1518a3f47e0bc7b6dbe 200 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 32 200 6.4E-60 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 276 1.9E-114 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 SUPERFAMILY SSF51658 1 277 4.58E-101 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 Pfam PF01261 Xylose isomerase-like TIM barrel 21 239 4.6E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 Gene3D G3DSA:3.20.20.150 1 285 2.7E-61 T 28-03-2018 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 SMART SM00518 3 279 1.5E-137 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 215 231 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 WM46_RS02405 de0b1cf2be80b5b27b69ebe557977117 285 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 279 44.408 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 225 253 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 130 158 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 259 285 0.23 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Gene3D G3DSA:2.160.10.10 23 138 2.8E-19 T 28-03-2018 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 329 7.6E-130 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 326 35.63 T 28-03-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 22 88 4.5E-22 T 28-03-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 SUPERFAMILY SSF51161 32 316 5.13E-87 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Gene3D G3DSA:2.160.10.10 139 309 1.4E-44 T 28-03-2018 WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 144 2.2E-9 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 222 255 3.6E-7 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13925 54a25cede6cdf2c272cd133ccfe2dad1 341 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 179 1.1E-7 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS23260 6761961aa8d950e8450ce357955c07a0 712 ProSitePatterns PS00850 Glycine radical domain signature. 676 684 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site WM46_RS23260 6761961aa8d950e8450ce357955c07a0 712 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 116 705 3.4E-183 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 WM46_RS23260 6761961aa8d950e8450ce357955c07a0 712 Gene3D G3DSA:3.20.70.20 121 687 5.5E-209 T 28-03-2018 WM46_RS23260 6761961aa8d950e8450ce357955c07a0 712 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 115 705 8.9E-211 T 28-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 WM46_RS23260 6761961aa8d950e8450ce357955c07a0 712 SUPERFAMILY SSF51998 121 687 2.5E-201 T 28-03-2018 WM46_RS23260 6761961aa8d950e8450ce357955c07a0 712 Pfam PF03477 ATP cone domain 4 89 1.4E-20 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 Pfam PF12838 4Fe-4S dicluster domain 107 154 5.4E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 Gene3D G3DSA:3.30.70.20 72 97 0.087 T 28-03-2018 WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 Gene3D G3DSA:3.30.70.20 15 45 0.02 T 28-03-2018 WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 SUPERFAMILY SSF54862 32 159 4.81E-20 T 28-03-2018 WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 TIGRFAM TIGR00402 napF: ferredoxin-type protein NapF 6 156 1.9E-64 T 28-03-2018 IPR004496 Ferredoxin-type protein NapF GO:0005506|GO:0009055|GO:0055114 WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 Pfam PF13187 4Fe-4S dicluster domain 35 81 1.7E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 Gene3D G3DSA:3.30.70.20 46 71 2.6E-9 T 28-03-2018 WM46_RS02130 872048495e9d6e7f090933a3e45164a5 163 Gene3D G3DSA:3.30.70.20 98 163 7.8E-11 T 28-03-2018 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 122 133 2.4E-14 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 111 121 2.4E-14 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 150 162 2.4E-14 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 Gene3D G3DSA:1.10.10.10 1 70 8.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 Hamap MF_00015 LexA repressor [lexA]. 3 199 32.817 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 Pfam PF01726 LexA DNA binding domain 1 65 1.9E-31 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 SUPERFAMILY SSF51306 76 198 4.36E-39 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 TIGRFAM TIGR00498 lexA: repressor LexA 1 199 7.2E-87 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 Gene3D G3DSA:2.10.109.10 80 198 7.5E-27 T 28-03-2018 WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 Pfam PF00717 Peptidase S24-like 114 179 7.6E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS21595 0f3323fa7a24619b5f8b9aad62f42cd7 202 SUPERFAMILY SSF46785 3 70 1.14E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 PIRSF PIRSF037215 1 408 3.2E-181 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 Gene3D G3DSA:3.40.630.10 1 408 2.6E-48 T 28-03-2018 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 SUPERFAMILY SSF53187 322 405 3.02E-83 T 28-03-2018 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 SUPERFAMILY SSF53187 1 209 3.02E-83 T 28-03-2018 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 SUPERFAMILY SSF55031 208 320 3.51E-43 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 176 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 407 1.7E-156 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 Hamap MF_00550 Peptidase T [pepT]. 1 404 55.609 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 Pfam PF01546 Peptidase family M20/M25/M40 139 402 5.0E-17 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 WM46_RS08510 1e6ac8820b993a61cdddb43c616c7f32 408 Pfam PF07687 Peptidase dimerisation domain 206 303 1.3E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 Gene3D G3DSA:3.10.105.10 311 511 1.6E-57 T 28-03-2018 WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 Gene3D G3DSA:3.90.76.10 62 174 2.6E-35 T 28-03-2018 WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 SUPERFAMILY SSF53850 34 524 1.99E-150 T 28-03-2018 WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 462 8.1E-91 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 PIRSF PIRSF002741 2 541 9.7E-116 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 Gene3D G3DSA:3.40.190.10 175 310 3.3E-39 T 28-03-2018 WM46_RS05745 65a645198ae8ccd1f4d18d86d7608cdb 542 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 86 107 - T 28-03-2018 IPR023765 Solute-binding protein family 5, conserved site WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 Pfam PF03797 Autotransporter beta-domain 715 952 1.2E-40 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 PRINTS PR01484 Pertactin virulence factor family signature 862 885 5.9E-9 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 PRINTS PR01484 Pertactin virulence factor family signature 891 912 5.9E-9 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 PRINTS PR01484 Pertactin virulence factor family signature 752 776 5.9E-9 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 PRINTS PR01484 Pertactin virulence factor family signature 928 953 5.9E-9 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 PRINTS PR01484 Pertactin virulence factor family signature 953 973 5.9E-9 T 28-03-2018 IPR003991 Pertactin virulence factor family GO:0007155 WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 Gene3D G3DSA:2.160.20.20 16 451 1.5E-15 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 Gene3D G3DSA:2.160.20.20 452 686 8.7E-8 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 577 973 1.1E-79 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 SUPERFAMILY SSF51126 173 258 1.16E-20 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 SUPERFAMILY SSF51126 288 672 1.16E-20 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 SMART SM00869 712 962 3.1E-39 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 SUPERFAMILY SSF103515 681 973 3.14E-51 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13050 c1eff3a7554a42e321af60259220e55a 973 Gene3D G3DSA:2.40.128.130 687 973 1.8E-45 T 28-03-2018 WM46_RS05565 2e3db57538b5f910fbc82604d60e3529 130 PIRSF PIRSF005610 1 125 2.2E-20 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB WM46_RS05565 2e3db57538b5f910fbc82604d60e3529 130 Pfam PF04247 Invasion gene expression up-regulator, SirB 7 127 3.5E-35 T 28-03-2018 IPR007360 Invasion gene expression up-regulator, SirB WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 2.5E-6 T 28-03-2018 WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.5E-6 T 28-03-2018 WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 SUPERFAMILY SSF54373 175 277 8.24E-17 T 28-03-2018 WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 Pfam PF01266 FAD dependent oxidoreductase 6 83 1.2E-9 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 SUPERFAMILY SSF51905 280 367 8.47E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 SUPERFAMILY SSF51905 1 177 8.47E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25200 b155f85555de36cfd40dbc3d18155772 423 Gene3D G3DSA:3.50.50.60 2 364 3.4E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS04795 a7a8506b1980b6ee5255f1068da7350d 1066 Pfam PF13550 Putative phage tail protein 339 501 6.2E-13 T 28-03-2018 IPR032876 Tip attachment protein J WM46_RS04795 a7a8506b1980b6ee5255f1068da7350d 1066 Gene3D G3DSA:2.60.40.10 619 828 2.6E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS04795 a7a8506b1980b6ee5255f1068da7350d 1066 Pfam PF09327 Domain of unknown function (DUF1983) 913 992 2.1E-23 T 28-03-2018 IPR015406 Domain of unknown function DUF1983 WM46_RS04795 a7a8506b1980b6ee5255f1068da7350d 1066 SUPERFAMILY SSF49265 606 718 1.24E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 WM46_RS08525 cb08618af4cd789bad23f3c76c703291 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 251 2.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08525 cb08618af4cd789bad23f3c76c703291 259 SUPERFAMILY SSF161098 3 255 1.21E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08525 cb08618af4cd789bad23f3c76c703291 259 Gene3D G3DSA:1.10.3720.10 5 259 1.7E-38 T 28-03-2018 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 127 5.2E-61 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 Gene3D G3DSA:3.90.79.10 1 129 5.3E-29 T 28-03-2018 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 PRINTS PR00502 NUDIX hydrolase family signature 33 47 3.5E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 PRINTS PR00502 NUDIX hydrolase family signature 47 62 3.5E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 SUPERFAMILY SSF55811 2 126 5.28E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 Pfam PF00293 NUDIX domain 7 125 5.2E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 PRINTS PR01401 Mutator MutT protein signature 77 90 5.7E-14 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 WM46_RS14335 2db0ec442ea6518cddcf64fbb0ab35af 130 PRINTS PR01401 Mutator MutT protein signature 2 23 5.7E-14 T 28-03-2018 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 Pfam PF09339 IclR helix-turn-helix domain 25 73 3.1E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 SMART SM00346 23 112 3.7E-25 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 20 265 2.9E-96 T 28-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 Gene3D G3DSA:1.10.10.10 16 90 2.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 SUPERFAMILY SSF46785 24 95 1.73E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 Gene3D G3DSA:3.30.450.40 91 268 7.4E-56 T 28-03-2018 IPR029016 GAF domain-like WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 SUPERFAMILY SSF55781 89 267 1.33E-50 T 28-03-2018 IPR029016 GAF domain-like WM46_RS06175 4a7555ce836ba809ef60097a3ef19fae 268 Pfam PF01614 Bacterial transcriptional regulator 139 264 1.0E-34 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS06870 d17098620f13d7dd0c4189964583020d 109 Pfam PF06411 HdeA/HdeB family 12 97 1.7E-21 T 28-03-2018 IPR010486 HNS-dependent expression A/B WM46_RS06870 d17098620f13d7dd0c4189964583020d 109 Gene3D G3DSA:1.10.890.10 28 101 1.4E-20 T 28-03-2018 WM46_RS06870 d17098620f13d7dd0c4189964583020d 109 ProDom PD070929 HDEB PRECURSOR SIGNAL EXPORTED PERIPLASMIC SECRETED ECS4389 10K-L SEQUENCING DIRECT 1 107 1.0E-48 T 28-03-2018 WM46_RS06870 d17098620f13d7dd0c4189964583020d 109 Hamap MF_00947 Acid stress chaperone HdeB [hdeB]. 2 104 27.765 T 28-03-2018 IPR028623 HNS-dependent expression B GO:0009268|GO:0051082 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 Pfam PF00355 Rieske [2Fe-2S] domain 113 164 1.8E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 13 173 5.2E-44 T 28-03-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 Gene3D G3DSA:2.102.10.10 51 179 2.0E-30 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 PRINTS PR00162 Rieske 2Fe-2S subunit signature 117 128 5.8E-12 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 PRINTS PR00162 Rieske 2Fe-2S subunit signature 150 162 5.8E-12 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 PRINTS PR00162 Rieske 2Fe-2S subunit signature 138 150 5.8E-12 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 9 45 8.4E-7 T 28-03-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 Gene3D G3DSA:1.20.5.510 9 44 3.2E-8 T 28-03-2018 WM46_RS05495 47cdf13aefd36a9eb7deeca3f17bb560 183 SUPERFAMILY SSF50022 36 176 5.92E-30 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM46_RS06475 818d7f414521cd969d76aba4ae83bdda 181 SUPERFAMILY SSF55729 8 175 1.1E-42 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS06475 818d7f414521cd969d76aba4ae83bdda 181 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 1.5E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS06475 818d7f414521cd969d76aba4ae83bdda 181 Gene3D G3DSA:3.40.630.30 2 177 1.7E-26 T 28-03-2018 WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 Pfam PF08274 PhnA Zinc-Ribbon 2 30 7.3E-16 T 28-03-2018 IPR013987 PhnA protein, N-terminal WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 Gene3D G3DSA:2.30.30.40 43 110 1.5E-37 T 28-03-2018 WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 SUPERFAMILY SSF82057 39 110 1.51E-29 T 28-03-2018 WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 SUPERFAMILY SSF57783 1 35 3.23E-14 T 28-03-2018 WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 Pfam PF03831 PhnA domain 44 111 1.0E-34 T 28-03-2018 IPR013988 PhnA protein, C-terminal WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 111 1.3E-61 T 28-03-2018 IPR004624 PhnA protein WM46_RS21905 37c302cb665fc0fc89a4fb17546da506 111 Gene3D G3DSA:2.20.25.10 1 39 3.0E-16 T 28-03-2018 WM46_RS03320 94f0588d437e6dbe3c9d3cab10066a49 500 PIRSF PIRSF007349 1 493 5.1E-159 T 28-03-2018 IPR007067 Tail sheath protein WM46_RS03320 94f0588d437e6dbe3c9d3cab10066a49 500 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 208 370 1.5E-18 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain WM46_RS03320 94f0588d437e6dbe3c9d3cab10066a49 500 Pfam PF17482 Phage tail sheath C-terminal domain 378 491 2.3E-9 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain WM46_RS05445 e28d956ddc0984d0e314a4e7d857fc2c 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 6.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS05445 e28d956ddc0984d0e314a4e7d857fc2c 183 Gene3D G3DSA:1.10.357.10 1 183 3.3E-23 T 28-03-2018 WM46_RS05445 e28d956ddc0984d0e314a4e7d857fc2c 183 SUPERFAMILY SSF46689 5 85 7.18E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 PIRSF PIRSF001604 1 670 1.5E-254 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 398 1.2E-35 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 331 346 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:1.10.287.610 1 67 3.4E-27 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 407 434 2.7E-10 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SUPERFAMILY SSF56091 2 316 1.73E-123 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Hamap MF_01588 DNA ligase [ligA]. 2 669 54.824 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SUPERFAMILY SSF50249 318 400 6.51E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Pfam PF14520 Helix-hairpin-helix domain 446 502 7.8E-6 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:3.40.50.10190 572 670 1.4E-24 T 28-03-2018 IPR001357 BRCT domain WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SMART SM00292 595 670 8.0E-14 T 28-03-2018 IPR001357 BRCT domain WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:3.30.1490.70 242 321 2.9E-23 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SMART SM00278 512 531 720.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SMART SM00278 480 499 1.9 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SMART SM00278 446 465 24.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SMART SM00278 544 563 37.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 665 4.1E-276 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:3.30.470.30 119 241 4.7E-53 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Pfam PF12826 Helix-hairpin-helix motif 510 573 1.5E-21 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:2.40.50.140 322 390 1.1E-34 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 318 1.9E-141 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SMART SM00532 3 448 6.3E-297 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SUPERFAMILY SSF47781 404 583 1.96E-60 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 SUPERFAMILY SSF52113 596 669 4.25E-19 T 28-03-2018 IPR001357 BRCT domain WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:1.10.150.20 506 571 1.2E-26 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Gene3D G3DSA:1.10.150.20 432 505 1.5E-26 T 28-03-2018 WM46_RS01155 96d61a0d9e3fdfd0211363e54932ffe3 671 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 596 669 1.6E-12 T 28-03-2018 IPR001357 BRCT domain WM46_RS02820 f9ae34cc7acb08071c4a0ae241af11fd 405 SUPERFAMILY SSF53756 11 405 2.2E-23 T 28-03-2018 WM46_RS02820 f9ae34cc7acb08071c4a0ae241af11fd 405 Gene3D G3DSA:3.40.50.2000 87 398 3.8E-15 T 28-03-2018 WM46_RS02820 f9ae34cc7acb08071c4a0ae241af11fd 405 TIGRFAM TIGR04015 WcaC: colanic acid biosynthesis glycosyltransferase WcaC 1 405 1.4E-267 T 28-03-2018 IPR023916 Colanic acid biosynthesis, glycosyl transferase, WcaC WM46_RS02820 f9ae34cc7acb08071c4a0ae241af11fd 405 Pfam PF13439 Glycosyltransferase Family 4 13 224 4.8E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 WM46_RS16240 af8f321112e898621cf91742299ba32c 310 Gene3D G3DSA:3.40.190.10 180 268 1.2E-26 T 28-03-2018 WM46_RS16240 af8f321112e898621cf91742299ba32c 310 SUPERFAMILY SSF46785 9 115 8.17E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16240 af8f321112e898621cf91742299ba32c 310 Gene3D G3DSA:1.10.10.10 8 96 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16240 af8f321112e898621cf91742299ba32c 310 Pfam PF03466 LysR substrate binding domain 93 296 1.9E-34 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS16240 af8f321112e898621cf91742299ba32c 310 SUPERFAMILY SSF53850 94 299 2.53E-38 T 28-03-2018 WM46_RS16240 af8f321112e898621cf91742299ba32c 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 5.4E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16240 af8f321112e898621cf91742299ba32c 310 Gene3D G3DSA:3.40.190.10 97 179 1.1E-8 T 28-03-2018 WM46_RS15520 90eb8bd329ba0bfaa471d6680fdf08ae 80 Pfam PF11660 Protein of unknown function (DUF3262) 3 79 2.1E-29 T 28-03-2018 IPR021676 Protein of unknown function DUF3262 WM46_RS15520 90eb8bd329ba0bfaa471d6680fdf08ae 80 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 4 80 4.8E-27 T 28-03-2018 IPR021676 Protein of unknown function DUF3262 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 Gene3D G3DSA:3.30.420.10 2 159 3.2E-52 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 159 2.4E-87 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 SUPERFAMILY SSF53098 3 156 1.29E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 7.3E-45 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 7.3E-45 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 7.3E-45 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 7.3E-45 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 7.3E-45 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 1.2E-68 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS04295 63b26899621f6fd7fe2c8518b5a73c81 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 46.911 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 SUPERFAMILY SSF51556 54 350 1.02E-100 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 Gene3D G3DSA:3.20.20.140 69 350 8.9E-93 T 28-03-2018 WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 Pfam PF01979 Amidohydrolase family 50 379 1.5E-47 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 SUPERFAMILY SSF51338 1 53 3.51E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 377 7.2E-180 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 Gene3D G3DSA:2.30.40.10 2 68 1.6E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS11225 db157d3e1b9ba8b26df1ca1b877326af 382 PIRSF PIRSF038994 1 382 2.0E-113 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Hamap MF_01166 Bifunctional polymyxin resistance protein ArnA [arnA]. 1 660 64.157 T 28-03-2018 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 SUPERFAMILY SSF53328 1 202 4.06E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 SUPERFAMILY SSF50486 204 302 6.28E-24 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Pfam PF00551 Formyl transferase 49 176 1.6E-24 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Pfam PF02911 Formyl transferase, C-terminal domain 202 292 5.4E-18 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Gene3D G3DSA:3.10.25.10 203 305 1.8E-21 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Gene3D G3DSA:3.40.50.720 314 659 3.8E-45 T 28-03-2018 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 PIRSF PIRSF036506 1 660 0.0 T 28-03-2018 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Gene3D G3DSA:3.40.50.170 1 201 5.2E-48 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 Pfam PF01370 NAD dependent epimerase/dehydratase family 318 566 2.3E-43 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS22390 0a67075c47c099ef44809830977e5c78 660 SUPERFAMILY SSF51735 317 651 1.48E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 SUPERFAMILY SSF53335 13 257 9.07E-62 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 Gene3D G3DSA:3.40.50.150 11 292 2.8E-59 T 28-03-2018 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 Pfam PF01555 DNA methylase 34 250 3.1E-50 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 214 232 1.0E-36 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 237 257 1.0E-36 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 68 88 1.0E-36 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 195 212 1.0E-36 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 33 47 1.0E-36 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS17255 dae93e775f9fca58ec0fc818f3c6d335 294 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 37 43 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS05415 d851614420237d4b103f62b407b6e46d 65 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 5 57 5.8E-16 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA WM46_RS05415 d851614420237d4b103f62b407b6e46d 65 SUPERFAMILY SSF46955 6 59 1.01E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS05415 d851614420237d4b103f62b407b6e46d 65 Gene3D G3DSA:1.10.10.10 6 65 3.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17240 2f9b890855b91a728c1792186f48629b 293 Gene3D G3DSA:3.40.50.150 99 292 6.7E-33 T 28-03-2018 WM46_RS17240 2f9b890855b91a728c1792186f48629b 293 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 286 7.5E-125 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 WM46_RS17240 2f9b890855b91a728c1792186f48629b 293 PIRSF PIRSF000401 1 293 6.4E-94 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 WM46_RS17240 2f9b890855b91a728c1792186f48629b 293 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 292 33.542 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 WM46_RS17240 2f9b890855b91a728c1792186f48629b 293 SUPERFAMILY SSF53335 42 291 5.72E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS17240 2f9b890855b91a728c1792186f48629b 293 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 293 1.2E-105 T 28-03-2018 WM46_RS16175 5f5e21a8e42c68138a3b8f0fab2f8899 224 Gene3D G3DSA:1.20.1550.10 15 224 1.1E-44 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain WM46_RS16175 5f5e21a8e42c68138a3b8f0fab2f8899 224 Pfam PF02600 Disulfide bond formation protein DsbB 26 213 8.7E-40 T 28-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 WM46_RS16175 5f5e21a8e42c68138a3b8f0fab2f8899 224 SUPERFAMILY SSF158442 188 213 6.15E-30 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain WM46_RS16175 5f5e21a8e42c68138a3b8f0fab2f8899 224 SUPERFAMILY SSF158442 29 158 6.15E-30 T 28-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain WM46_RS16175 5f5e21a8e42c68138a3b8f0fab2f8899 224 Hamap MF_01311 Protein-disulfide oxidoreductase DsbI [dsbI]. 7 224 57.335 T 28-03-2018 IPR023792 Protein-disulfide oxidoreductase DsbI WM46_RS11505 3bab8d676059372a8515428fde1e39ba 487 PIRSF PIRSF002457 1 487 6.3E-162 T 28-03-2018 IPR030676 Citrate carrier CitT-related WM46_RS11505 3bab8d676059372a8515428fde1e39ba 487 Pfam PF00939 Sodium:sulfate symporter transmembrane region 6 486 6.4E-184 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS11505 3bab8d676059372a8515428fde1e39ba 487 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 25 480 2.4E-170 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 36.437 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 Gene3D G3DSA:1.10.287.80 2 41 2.9E-18 T 28-03-2018 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 Gene3D G3DSA:1.10.287.80 240 282 5.3E-14 T 28-03-2018 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 Pfam PF00231 ATP synthase 5 286 2.0E-95 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 SUPERFAMILY SSF52943 2 287 5.1E-97 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 3.4E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 3.4E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 3.4E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 3.4E-37 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 Gene3D G3DSA:3.40.1380.10 42 239 2.6E-74 T 28-03-2018 WM46_RS19520 4e8be8e36d70a4f93ac2ecd648e2a796 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 2.9E-112 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS17795 e7c12ba324650ee71f2c257db0b11512 134 Pfam PF10748 Protein of unknown function (DUF2531) 6 134 3.6E-51 T 28-03-2018 IPR019684 HofP protein WM46_RS02795 a8f083d020e3181dbc405e2349e68a01 378 Gene3D G3DSA:3.10.560.10 161 251 7.8E-25 T 28-03-2018 WM46_RS02795 a8f083d020e3181dbc405e2349e68a01 378 Gene3D G3DSA:3.10.560.10 252 345 1.2E-15 T 28-03-2018 WM46_RS02795 a8f083d020e3181dbc405e2349e68a01 378 Pfam PF10531 SLBB domain 173 220 3.9E-6 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS02795 a8f083d020e3181dbc405e2349e68a01 378 Gene3D G3DSA:3.30.1950.10 89 160 1.2E-24 T 28-03-2018 WM46_RS02795 a8f083d020e3181dbc405e2349e68a01 378 Pfam PF02563 Polysaccharide biosynthesis/export protein 82 165 4.4E-26 T 28-03-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 WM46_RS02795 a8f083d020e3181dbc405e2349e68a01 378 Gene3D G3DSA:1.20.5.70 346 375 3.4E-15 T 28-03-2018 WM46_RS12205 d4ebdd8b59a764051ff038e2e5640e35 174 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 168 2.3E-33 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 SUPERFAMILY SSF46689 251 299 1.12E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 252 294 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 Gene3D G3DSA:1.10.10.60 206 251 2.8E-8 T 28-03-2018 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 Gene3D G3DSA:1.10.10.60 252 310 1.4E-13 T 28-03-2018 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 267 282 6.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 298 6.8E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 Gene3D G3DSA:2.60.120.280 19 205 2.0E-8 T 28-03-2018 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 SMART SM00342 215 298 8.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 Pfam PF12833 Helix-turn-helix domain 222 299 8.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 SUPERFAMILY SSF51182 35 114 5.01E-8 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS21965 19f11ac5dcdcb2ce9e603e142b154bd9 311 SUPERFAMILY SSF47454 137 194 1.57E-11 T 28-03-2018 IPR008917 Transcription factor, Skn-1-like, DNA-binding domain GO:0003677|GO:0006355 WM46_RS06540 76bd7d17a3894bfe52031639f07f0144 63 SUPERFAMILY SSF54786 2 59 2.71E-10 T 28-03-2018 WM46_RS06540 76bd7d17a3894bfe52031639f07f0144 63 Gene3D G3DSA:3.30.920.30 1 63 6.8E-11 T 28-03-2018 WM46_RS06540 76bd7d17a3894bfe52031639f07f0144 63 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 5 57 6.6E-10 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 WM46_RS22975 3014653b2a8244f7d549045353d13ca8 91 SUPERFAMILY SSF159871 2 91 2.22E-24 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS22975 3014653b2a8244f7d549045353d13ca8 91 Gene3D G3DSA:3.30.1660.10 20 91 1.3E-22 T 28-03-2018 IPR025543 Dodecin-like WM46_RS22975 3014653b2a8244f7d549045353d13ca8 91 Pfam PF07338 Protein of unknown function (DUF1471) 36 91 3.1E-19 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS15805 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF01548 Transposase 14 168 6.3E-44 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM46_RS15805 af51d47ae3af943b1629689cbf8b1598 398 Gene3D G3DSA:3.30.420.40 9 322 0.0017 T 28-03-2018 WM46_RS15805 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF02371 Transposase IS116/IS110/IS902 family 277 358 4.2E-22 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM46_RS18335 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF01548 Transposase 14 168 6.3E-44 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM46_RS18335 af51d47ae3af943b1629689cbf8b1598 398 Gene3D G3DSA:3.30.420.40 9 322 0.0017 T 28-03-2018 WM46_RS18335 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF02371 Transposase IS116/IS110/IS902 family 277 358 4.2E-22 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM46_RS15640 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF01548 Transposase 14 168 6.3E-44 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM46_RS15640 af51d47ae3af943b1629689cbf8b1598 398 Gene3D G3DSA:3.30.420.40 9 322 0.0017 T 28-03-2018 WM46_RS15640 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF02371 Transposase IS116/IS110/IS902 family 277 358 4.2E-22 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM46_RS03170 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF01548 Transposase 14 168 6.3E-44 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM46_RS03170 af51d47ae3af943b1629689cbf8b1598 398 Gene3D G3DSA:3.30.420.40 9 322 0.0017 T 28-03-2018 WM46_RS03170 af51d47ae3af943b1629689cbf8b1598 398 Pfam PF02371 Transposase IS116/IS110/IS902 family 277 358 4.2E-22 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 3.2E-91 T 28-03-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 SMART SM00862 146 221 1.3E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 SUPERFAMILY SSF52172 1 173 6.34E-38 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 Gene3D G3DSA:1.10.10.10 121 226 3.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 SMART SM00448 1 111 3.5E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 Gene3D G3DSA:3.40.50.2300 1 120 5.4E-34 T 28-03-2018 WM46_RS11880 77d404b78108e4a2eb1f7a3d24131dbc 226 Pfam PF00072 Response regulator receiver domain 4 112 2.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS26110 aea97ddcc2c587f9c60ab8b377acb6ad 262 Pfam PF13427 Domain of unknown function (DUF4111) 152 253 2.1E-32 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 WM46_RS26110 aea97ddcc2c587f9c60ab8b377acb6ad 262 Gene3D G3DSA:3.30.460.10 2 257 4.3E-12 T 28-03-2018 WM46_RS26110 aea97ddcc2c587f9c60ab8b377acb6ad 262 SUPERFAMILY SSF81301 7 102 9.81E-13 T 28-03-2018 WM46_RS26110 aea97ddcc2c587f9c60ab8b377acb6ad 262 PIRSF PIRSF000819 8 262 2.2E-53 T 28-03-2018 IPR024172 Streptomycin 3''-adenylyltransferase GO:0009012|GO:0046677 WM46_RS26110 aea97ddcc2c587f9c60ab8b377acb6ad 262 Pfam PF01909 Nucleotidyltransferase domain 28 98 1.9E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 185 202 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 6 295 2.8E-124 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 2 295 43.136 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 Gene3D G3DSA:1.10.8.10 269 296 0.12 T 28-03-2018 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 Gene3D G3DSA:1.10.8.10 240 268 4.0E-9 T 28-03-2018 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 Pfam PF01380 SIS domain 126 207 9.8E-10 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 SUPERFAMILY SSF53697 4 248 1.56E-75 T 28-03-2018 WM46_RS00440 86b0d19d5c9b3be5b76f30685a8c9c4d 300 Gene3D G3DSA:3.40.50.10490 10 239 9.8E-57 T 28-03-2018 WM46_RS16540 11ddff1b70dc6c6094faa990879ae088 444 SUPERFAMILY SSF103473 6 443 1.31E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS16540 11ddff1b70dc6c6094faa990879ae088 444 Pfam PF07690 Major Facilitator Superfamily 23 366 3.5E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS16540 11ddff1b70dc6c6094faa990879ae088 444 PIRSF PIRSF002808 3 444 1.6E-35 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS16540 11ddff1b70dc6c6094faa990879ae088 444 Gene3D G3DSA:1.20.1250.20 6 229 1.4E-35 T 28-03-2018 WM46_RS16540 11ddff1b70dc6c6094faa990879ae088 444 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 25 434 5.9E-138 T 28-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS16540 11ddff1b70dc6c6094faa990879ae088 444 Gene3D G3DSA:1.20.1250.20 239 444 3.0E-25 T 28-03-2018 WM46_RS17025 e4c0ac29a110eca66984f63852557df3 166 PIRSF PIRSF005276 3 166 3.6E-60 T 28-03-2018 IPR007481 Stringent starvation protein B WM46_RS17025 e4c0ac29a110eca66984f63852557df3 166 Gene3D G3DSA:2.30.30.220 10 107 8.1E-42 T 28-03-2018 IPR007481 Stringent starvation protein B WM46_RS17025 e4c0ac29a110eca66984f63852557df3 166 Pfam PF04386 Stringent starvation protein B 9 166 1.4E-44 T 28-03-2018 IPR007481 Stringent starvation protein B WM46_RS17025 e4c0ac29a110eca66984f63852557df3 166 SUPERFAMILY SSF101738 4 112 3.14E-48 T 28-03-2018 IPR007481 Stringent starvation protein B WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 Gene3D G3DSA:3.30.1490.20 129 197 1.2E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 Pfam PF02222 ATP-grasp domain 123 295 2.0E-56 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 390 2.1E-192 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 Gene3D G3DSA:3.30.470.20 198 392 1.9E-36 T 28-03-2018 WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 SUPERFAMILY SSF52440 3 112 9.5E-37 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 SUPERFAMILY SSF51246 319 391 1.02E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 391 51.773 T 28-03-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 Gene3D G3DSA:3.40.50.20 14 112 2.0E-20 T 28-03-2018 WM46_RS04360 e7d2b474204efe04382a7acabaa1cee2 392 SUPERFAMILY SSF56059 113 314 1.94E-55 T 28-03-2018 WM46_RS21590 3607e9af2b1e9a39d1f01084014caf81 122 Pfam PF01219 Prokaryotic diacylglycerol kinase 16 117 3.9E-35 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 WM46_RS21590 3607e9af2b1e9a39d1f01084014caf81 122 Gene3D G3DSA:1.10.3830.10 7 119 9.0E-44 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 WM46_RS21590 3607e9af2b1e9a39d1f01084014caf81 122 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 70 81 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 WM46_RS13290 809aa319624216106aff8e5599dee625 387 SUPERFAMILY SSF50969 71 108 8.63E-23 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like WM46_RS13290 809aa319624216106aff8e5599dee625 387 SUPERFAMILY SSF50969 142 364 8.63E-23 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like WM46_RS13290 809aa319624216106aff8e5599dee625 387 Gene3D G3DSA:2.130.10.10 9 377 1.1E-32 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 SUPERFAMILY SSF46689 179 230 1.47E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 SUPERFAMILY SSF46689 232 280 9.86E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 Gene3D G3DSA:1.10.10.60 175 234 1.1E-12 T 28-03-2018 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 SMART SM00342 196 279 6.0E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 Pfam PF12833 Helix-turn-helix domain 202 277 3.8E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 233 275 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 Gene3D G3DSA:1.10.10.60 235 285 2.7E-9 T 28-03-2018 WM46_RS15215 16e6a51f90de08edcecc4512123007f3 286 Pfam PF06719 AraC-type transcriptional regulator N-terminus 19 167 8.3E-36 T 28-03-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 Gene3D G3DSA:3.40.50.850 1 209 1.4E-47 T 28-03-2018 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PIRSF PIRSF001111 1 285 3.9E-130 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 Pfam PF00550 Phosphopantetheine attachment site 216 276 4.0E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 SUPERFAMILY SSF47336 209 280 3.01E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 Pfam PF00857 Isochorismatase family 32 204 5.7E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 SUPERFAMILY SSF52499 1 210 2.49E-64 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 Gene3D G3DSA:1.10.1200.10 210 285 9.3E-9 T 28-03-2018 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PRINTS PR01398 Isochorismatase signature 112 134 1.7E-50 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PRINTS PR01398 Isochorismatase signature 63 80 1.7E-50 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PRINTS PR01398 Isochorismatase signature 186 203 1.7E-50 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PRINTS PR01398 Isochorismatase signature 2 14 1.7E-50 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PRINTS PR01398 Isochorismatase signature 168 186 1.7E-50 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS11580 5a7de5085457b97babc2bf3c0767db99 285 PRINTS PR01398 Isochorismatase signature 80 99 1.7E-50 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 WM46_RS19430 18795d3c641395283c300603d51bf61d 321 Gene3D G3DSA:1.10.3470.10 33 320 2.1E-37 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS19430 18795d3c641395283c300603d51bf61d 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 313 8.4E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS18325 0c4fa3c532e03d02fa8796ef204bc569 195 SUPERFAMILY SSF56214 30 79 1.57E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS18325 0c4fa3c532e03d02fa8796ef204bc569 195 SUPERFAMILY SSF56214 87 180 3.92E-15 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS18325 0c4fa3c532e03d02fa8796ef204bc569 195 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 88 149 4.5E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS18325 0c4fa3c532e03d02fa8796ef204bc569 195 Gene3D G3DSA:3.90.470.20 99 177 6.8E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS18325 0c4fa3c532e03d02fa8796ef204bc569 195 Gene3D G3DSA:3.90.470.20 19 98 1.8E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS03335 c30dbc5203db283e6a0cacf25527afa3 619 Gene3D G3DSA:1.20.5.1230 10 527 4.9E-4 T 28-03-2018 WM46_RS07560 2f8119a776a9ba88b04271c10b4f888d 364 Gene3D G3DSA:2.60.40.1090 93 196 0.0041 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07560 2f8119a776a9ba88b04271c10b4f888d 364 Gene3D G3DSA:2.60.40.1090 210 364 1.7E-25 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07560 2f8119a776a9ba88b04271c10b4f888d 364 Pfam PF00419 Fimbrial protein 216 364 1.2E-13 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07560 2f8119a776a9ba88b04271c10b4f888d 364 SUPERFAMILY SSF49401 223 364 4.37E-19 T 28-03-2018 IPR008966 Adhesion domain WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 SUPERFAMILY SSF52833 1 72 1.79E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 TIGRFAM TIGR02182 GRXB: glutaredoxin, GrxB family 2 210 1.3E-98 T 28-03-2018 IPR011901 Glutaredoxin-2 GO:0005829|GO:0097573 WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 ProSitePatterns PS00195 Glutaredoxin active site. 3 18 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 SUPERFAMILY SSF47616 76 215 5.78E-48 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 Gene3D G3DSA:3.40.30.10 1 101 5.6E-14 T 28-03-2018 WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 74 3.8E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 Pfam PF04399 Glutaredoxin 2, C terminal domain 86 214 2.7E-49 T 28-03-2018 IPR007494 Glutaredoxin 2, C-terminal WM46_RS08840 a3eb877af8534a9288fd91da81de0b84 215 Gene3D G3DSA:1.20.1050.10 102 215 6.0E-32 T 28-03-2018 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 SUPERFAMILY SSF53383 101 559 3.2E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 PIRSF PIRSF009393 1 711 1.5E-284 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Gene3D G3DSA:3.90.1150.10 413 592 3.0E-54 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Gene3D G3DSA:3.90.100.10 593 711 6.6E-34 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 4 76 1.3E-13 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 SUPERFAMILY SSF52172 1 100 2.14E-24 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 568 697 9.2E-46 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Gene3D G3DSA:3.40.50.220 3 100 2.7E-23 T 28-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 SUPERFAMILY SSF55904 563 711 3.66E-44 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 101 542 6.8E-200 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 Gene3D G3DSA:3.40.640.10 101 412 9.0E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS15155 5a2a55c8d677ece2245208b029b8bec5 711 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 342 356 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 394 7.1E-191 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 SUPERFAMILY SSF54631 276 394 5.05E-13 T 28-03-2018 WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 SUPERFAMILY SSF52540 43 270 4.84E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 SMART SM00382 53 242 7.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 Pfam PF00005 ABC transporter 45 192 1.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 Gene3D G3DSA:3.40.50.300 2 276 1.1E-76 T 28-03-2018 WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 Pfam PF00571 CBS domain 346 393 3.4E-6 T 28-03-2018 IPR000644 CBS domain WM46_RS25630 565a4574bc3e44a146011ca9edf0527a 400 Gene3D G3DSA:3.10.580.10 277 399 2.8E-12 T 28-03-2018 WM46_RS13585 6388ad7d21dcc337acfbe971a81e7999 433 Pfam PF10926 Protein of unknown function (DUF2800) 5 410 1.5E-121 T 28-03-2018 IPR021229 Protein of unknown function DUF2800 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 SUPERFAMILY SSF143437 1 173 5.76E-51 T 28-03-2018 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Gene3D G3DSA:3.40.250.10 405 481 4.6E-10 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 SUPERFAMILY SSF52402 174 372 1.85E-41 T 28-03-2018 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Gene3D G3DSA:3.30.70.1510 2 82 1.1E-21 T 28-03-2018 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 SUPERFAMILY SSF52821 403 481 1.82E-9 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Gene3D G3DSA:3.30.2300.10 84 162 4.9E-22 T 28-03-2018 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 SMART SM00981 75 165 7.8E-27 T 28-03-2018 IPR004114 THUMP domain GO:0003723 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 377 3.9E-145 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 2.5E-80 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 383 482 1.1E-40 T 28-03-2018 IPR026340 Thiazole biosynthesis domain GO:0052837 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 482 232.577 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Pfam PF02926 THUMP domain 28 161 2.0E-29 T 28-03-2018 IPR004114 THUMP domain GO:0003723 WM46_RS12730 0453ba832ef2c272ae5a73e4ecb0258b 482 Gene3D G3DSA:3.40.50.620 175 400 3.4E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS17005 1da0b67b1f94e54dd1fe54898ad17f85 229 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 35 225 9.9E-88 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 WM46_RS17005 1da0b67b1f94e54dd1fe54898ad17f85 229 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 11 225 36.908 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 WM46_RS17005 1da0b67b1f94e54dd1fe54898ad17f85 229 Gene3D G3DSA:3.20.20.70 1 229 2.6E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS17005 1da0b67b1f94e54dd1fe54898ad17f85 229 SUPERFAMILY SSF51366 14 224 5.02E-54 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS00175 f4d54a21a1b1e83ab521ac04ba8a473c 263 Pfam PF01578 Cytochrome C assembly protein 36 261 6.5E-46 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 Pfam PF00535 Glycosyl transferase family 2 276 446 1.1E-34 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 593 612 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 282 301 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 199 219 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 667 688 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 524 550 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 227 252 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 363 387 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 PRINTS PR01439 Cellulose synthase subunit A signature 553 572 1.6E-56 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 SUPERFAMILY SSF53448 272 550 6.19E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 TIGRFAM TIGR03030 CelA: cellulose synthase catalytic subunit (UDP-forming) 147 829 0.0 T 28-03-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 Gene3D G3DSA:3.90.550.10 273 512 1.0E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 SUPERFAMILY SSF141371 695 777 3.34E-8 T 28-03-2018 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 Gene3D G3DSA:2.40.10.220 690 798 1.1E-13 T 28-03-2018 WM46_RS20660 d9442d81efbec97dca545a58b0df9788 873 Pfam PF07238 PilZ domain 694 790 1.4E-10 T 28-03-2018 IPR009875 PilZ domain GO:0035438 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 SMART SM01061 1 59 4.1E-27 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 Gene3D G3DSA:2.30.24.10 1 54 2.8E-22 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 Pfam PF00874 PRD domain 179 271 8.6E-15 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 Pfam PF00874 PRD domain 78 161 1.3E-22 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 Pfam PF03123 CAT RNA binding domain 1 54 4.6E-21 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 Gene3D G3DSA:1.10.1790.10 164 276 1.0E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 Gene3D G3DSA:1.10.1790.10 55 163 3.4E-24 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 SUPERFAMILY SSF63520 58 165 3.01E-27 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 SUPERFAMILY SSF63520 171 273 1.83E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 SUPERFAMILY SSF50151 1 54 4.97E-16 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 WM46_RS15330 950158737c74a5ece4d8f8bfc1b13b9e 279 ProSitePatterns PS00654 PRD domain signature. 97 109 - T 28-03-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Gene3D G3DSA:3.40.50.740 257 536 5.9E-79 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 PIRSF PIRSF000144 535 693 1.6 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 PIRSF PIRSF000144 53 444 8.4E-54 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Pfam PF00384 Molybdopterin oxidoreductase 61 488 7.2E-88 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 435 452 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 53 1.8E-12 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 SUPERFAMILY SSF50692 542 688 1.47E-42 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 SUPERFAMILY SSF53706 1 564 3.01E-191 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 616 643 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Gene3D G3DSA:3.40.228.10 168 256 1.7E-24 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 7 686 5.4E-273 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Pfam PF01568 Molydopterin dinucleotide binding domain 576 683 1.6E-26 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Gene3D G3DSA:1.20.5.460 691 713 3.8E-10 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 SMART SM00926 1 54 1.0E-14 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Gene3D G3DSA:2.20.25.90 1 55 1.2E-15 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Gene3D G3DSA:2.40.40.20 537 688 1.4E-37 T 28-03-2018 WM46_RS08435 8e5fad90a07336bd7a81c7eb0bc2f956 715 Gene3D G3DSA:3.40.50.740 61 167 1.9E-25 T 28-03-2018 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 Pfam PF01479 S4 domain 97 143 7.3E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 SUPERFAMILY SSF55174 3 206 2.09E-73 T 28-03-2018 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 2.7E-87 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.37 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 Gene3D G3DSA:1.10.1050.10 145 206 7.9E-18 T 28-03-2018 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 SMART SM01390 3 95 1.3E-49 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 SMART SM00363 96 160 8.2E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 Gene3D G3DSA:1.10.1050.10 1 101 2.4E-41 T 28-03-2018 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 1.7E-32 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 WM46_RS17425 80651f80fa5f50ccf533ac137a42bee0 206 Gene3D G3DSA:3.10.290.10 102 144 1.3E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS25715 83e4d128e786d4704f937a1903640d22 466 Pfam PF00324 Amino acid permease 18 455 3.0E-124 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS25715 83e4d128e786d4704f937a1903640d22 466 TIGRFAM TIGR01773 GABAperm: GABA permease 1 452 1.4E-251 T 28-03-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 WM46_RS25715 83e4d128e786d4704f937a1903640d22 466 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS25715 83e4d128e786d4704f937a1903640d22 466 PIRSF PIRSF006060 1 460 9.1E-73 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS20375 116aa17510f1dd07ad304148f1043244 510 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 298 309 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS20375 116aa17510f1dd07ad304148f1043244 510 Pfam PF00171 Aldehyde dehydrogenase family 31 496 9.1E-165 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS20375 116aa17510f1dd07ad304148f1043244 510 Gene3D G3DSA:3.40.309.10 283 484 2.8E-65 T 28-03-2018 WM46_RS20375 116aa17510f1dd07ad304148f1043244 510 Gene3D G3DSA:3.40.605.10 16 282 1.5E-95 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS20375 116aa17510f1dd07ad304148f1043244 510 SUPERFAMILY SSF53720 19 503 1.23E-161 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS20375 116aa17510f1dd07ad304148f1043244 510 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS23455 a46468c259cfba958b251aeed7344a25 347 SUPERFAMILY SSF51735 145 303 1.91E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23455 a46468c259cfba958b251aeed7344a25 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 139 8.7E-27 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS23455 a46468c259cfba958b251aeed7344a25 347 Gene3D G3DSA:3.40.50.720 163 316 8.1E-23 T 28-03-2018 WM46_RS23455 a46468c259cfba958b251aeed7344a25 347 SUPERFAMILY SSF50129 9 176 1.73E-38 T 28-03-2018 IPR011032 GroES-like WM46_RS23455 a46468c259cfba958b251aeed7344a25 347 Pfam PF00107 Zinc-binding dehydrogenase 180 304 8.5E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS23455 a46468c259cfba958b251aeed7344a25 347 Gene3D G3DSA:3.90.180.10 8 162 3.8E-31 T 28-03-2018 WM46_RS14050 d60eb40464149c8dd9438672d9f2570a 660 SUPERFAMILY SSF81345 347 657 3.53E-72 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS14050 d60eb40464149c8dd9438672d9f2570a 660 SUPERFAMILY SSF81345 7 325 2.75E-59 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS14050 d60eb40464149c8dd9438672d9f2570a 660 Gene3D G3DSA:1.10.3470.10 1 333 1.1E-49 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS14050 d60eb40464149c8dd9438672d9f2570a 660 Gene3D G3DSA:1.10.3470.10 342 660 2.3E-46 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS14050 d60eb40464149c8dd9438672d9f2570a 660 Pfam PF01032 FecCD transport family 18 323 6.0E-64 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS14050 d60eb40464149c8dd9438672d9f2570a 660 Pfam PF01032 FecCD transport family 379 657 1.4E-74 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 3.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 PRINTS PR00151 Porphobilinogen deaminase signature 45 65 3.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 PRINTS PR00151 Porphobilinogen deaminase signature 230 247 3.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 PRINTS PR00151 Porphobilinogen deaminase signature 76 95 3.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 3.6E-49 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 SUPERFAMILY SSF53850 5 219 4.75E-86 T 28-03-2018 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 6 212 7.2E-79 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 6 297 1.0E-111 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 Gene3D G3DSA:3.40.190.10 107 199 9.9E-38 T 28-03-2018 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 Gene3D G3DSA:3.40.190.10 2 106 2.9E-44 T 28-03-2018 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 SUPERFAMILY SSF54782 220 308 3.79E-28 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 5 297 39.784 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 295 3.4E-23 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 231 247 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 PIRSF PIRSF001438 1 311 2.2E-122 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19140 339357817ee476350e37a92cbf08b6f0 313 Gene3D G3DSA:3.30.160.40 221 306 2.1E-24 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PIRSF PIRSF000106 1 563 1.3E-225 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 ProSitePatterns PS00331 Malic enzymes signature. 267 283 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 Gene3D G3DSA:3.40.50.10380 15 268 4.3E-112 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 SUPERFAMILY SSF51735 271 562 1.63E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 SMART SM01274 81 261 1.3E-106 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 SMART SM00919 271 531 1.6E-131 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 Pfam PF03949 Malic enzyme, NAD binding domain 271 530 2.5E-104 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 267 283 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 183 205 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 147 176 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 408 424 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 298 314 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 242 260 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 PRINTS PR00072 Malic enzyme signature 87 111 5.2E-73 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 Hamap MF_01619 NAD-dependent malic enzyme [maeA]. 4 565 72.287 T 28-03-2018 IPR023667 NAD-dependent malic enzyme, proteobacteria GO:0004471|GO:0055114 KEGG: 00620+1.1.1.38 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 Pfam PF00390 Malic enzyme, N-terminal domain 81 261 5.4E-79 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 Gene3D G3DSA:3.40.50.720 269 565 7.8E-106 T 28-03-2018 WM46_RS06820 8269a37079fbf6299e752431969e20a3 565 SUPERFAMILY SSF53223 9 270 6.4E-109 T 28-03-2018 WM46_RS04110 1316fb987d1e7eeebf7c7e0bd2850128 192 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 172 2.4E-82 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 WM46_RS04110 1316fb987d1e7eeebf7c7e0bd2850128 192 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 186 45.464 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 WM46_RS04110 1316fb987d1e7eeebf7c7e0bd2850128 192 SUPERFAMILY SSF160930 5 160 4.18E-64 T 28-03-2018 WM46_RS04110 1316fb987d1e7eeebf7c7e0bd2850128 192 PIRSF PIRSF003159 1 181 6.5E-92 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 WM46_RS04110 1316fb987d1e7eeebf7c7e0bd2850128 192 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 192 2.0E-106 T 28-03-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 Gene3D G3DSA:1.50.10.10 39 542 3.7E-157 T 28-03-2018 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 Hamap MF_01060 Periplasmic trehalase [treA]. 2 539 83.511 T 28-03-2018 IPR023720 Trehalase, periplasmic GO:0004555|GO:0005993|GO:0042597|GO:0071474 KEGG: 00500+3.2.1.28 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 Pfam PF01204 Trehalase 61 537 3.0E-174 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 196 214 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 271 288 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 337 354 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 444 460 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 521 534 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 305 322 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 PRINTS PR00744 Glycosyl hydrolase family 37 signature 380 396 3.5E-49 T 28-03-2018 IPR001661 Glycoside hydrolase, family 37 GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 ProSitePatterns PS00928 Trehalase signature 2. 451 460 - T 28-03-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 SUPERFAMILY SSF48208 44 542 2.87E-174 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS05215 a34711337b73f4ad8178d5d9af267a69 568 ProSitePatterns PS00927 Trehalase signature 1. 154 167 - T 28-03-2018 IPR018232 Glycoside hydrolase, family 37, conserved site GO:0004555|GO:0005991 KEGG: 00500+3.2.1.28|Reactome: R-HSA-189085 WM46_RS19825 13e05145bd0ae0f00693012eda2444f5 437 Gene3D G3DSA:1.20.1250.20 15 237 1.2E-18 T 28-03-2018 WM46_RS19825 13e05145bd0ae0f00693012eda2444f5 437 Pfam PF07690 Major Facilitator Superfamily 45 274 4.1E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19825 13e05145bd0ae0f00693012eda2444f5 437 SUPERFAMILY SSF103473 13 424 6.54E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19825 13e05145bd0ae0f00693012eda2444f5 437 Gene3D G3DSA:1.20.1250.20 238 427 4.4E-21 T 28-03-2018 WM46_RS19825 13e05145bd0ae0f00693012eda2444f5 437 TIGRFAM TIGR00885 fucP: L-fucose:H+ symporter permease 21 424 2.7E-97 T 28-03-2018 IPR005275 L-fucose permease FucP GO:0015150|GO:0015756 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 Pfam PF01416 tRNA pseudouridine synthase 17 111 3.1E-9 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 Pfam PF01416 tRNA pseudouridine synthase 151 253 1.6E-28 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 Gene3D G3DSA:3.30.70.580 8 113 7.7E-35 T 28-03-2018 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 10 247 4.4E-82 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 SUPERFAMILY SSF55120 9 265 4.17E-93 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 PIRSF PIRSF001430 9 261 6.7E-78 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 Gene3D G3DSA:3.30.70.660 114 251 3.4E-38 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01570 bb4e6012573a2437349639e51982bdab 270 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 10 252 35.751 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS22275 dfefd229ffff5fc1b32afe95c40a92c5 369 Pfam PF01757 Acyltransferase family 36 344 1.7E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 WM46_RS04315 778f5fa11dddd2e8cbd807cfe07fd352 251 Pfam PF00005 ABC transporter 20 149 6.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS04315 778f5fa11dddd2e8cbd807cfe07fd352 251 SMART SM00382 29 199 3.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS04315 778f5fa11dddd2e8cbd807cfe07fd352 251 SUPERFAMILY SSF52540 3 214 2.8E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS04315 778f5fa11dddd2e8cbd807cfe07fd352 251 Gene3D G3DSA:3.40.50.300 1 239 4.3E-56 T 28-03-2018 WM46_RS05050 3e36f4a7fd2062be10daaff6eff2bc38 120 SUPERFAMILY SSF51197 1 106 8.79E-34 T 28-03-2018 WM46_RS05050 3e36f4a7fd2062be10daaff6eff2bc38 120 Gene3D G3DSA:2.60.120.10 5 109 3.0E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS05050 3e36f4a7fd2062be10daaff6eff2bc38 120 PIRSF PIRSF020632 1 120 6.9E-52 T 28-03-2018 IPR014510 Tellurite resistance predicted, YeaR WM46_RS05050 3e36f4a7fd2062be10daaff6eff2bc38 120 Pfam PF09313 Domain of unknown function (DUF1971) 12 96 9.3E-24 T 28-03-2018 IPR015392 Domain of unknown function DUF1971 WM46_RS24335 aea74bfb3b9874105e7140c9af364432 255 TIGRFAM TIGR03172 TIGR03172: putative selenium-dependent hydroxylase accessory protein YqeC 21 242 1.8E-75 T 28-03-2018 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC WM46_RS24335 aea74bfb3b9874105e7140c9af364432 255 Gene3D G3DSA:3.40.1190.10 13 137 1.0E-9 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS24335 aea74bfb3b9874105e7140c9af364432 255 SUPERFAMILY SSF53623 12 60 1.28E-8 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS22990 0b6e38c5dad94101f58f0a6aa7aec8db 104 Pfam PF00436 Single-strand binding protein family 3 87 7.4E-13 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 WM46_RS22990 0b6e38c5dad94101f58f0a6aa7aec8db 104 SUPERFAMILY SSF50249 1 103 2.67E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22990 0b6e38c5dad94101f58f0a6aa7aec8db 104 PIRSF PIRSF003135 1 101 4.0E-50 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 WM46_RS22990 0b6e38c5dad94101f58f0a6aa7aec8db 104 Hamap MF_00720 Primosomal replication protein N [priB]. 2 100 23.825 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 WM46_RS22990 0b6e38c5dad94101f58f0a6aa7aec8db 104 Gene3D G3DSA:2.40.50.140 2 104 1.1E-12 T 28-03-2018 WM46_RS22990 0b6e38c5dad94101f58f0a6aa7aec8db 104 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 3 99 2.7E-36 T 28-03-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 344 1.8E-35 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 347 1.7E-111 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 Gene3D G3DSA:3.40.50.2000 179 347 4.4E-30 T 28-03-2018 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 SUPERFAMILY SSF53756 6 353 5.73E-130 T 28-03-2018 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 9 145 3.8E-48 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 353 35.026 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14380 bfd80f49ad492ebf0fb0de55f6c7c547 355 Gene3D G3DSA:3.40.50.2000 1 178 1.2E-44 T 28-03-2018 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 Hamap MF_01055 Protein FixA [fixA]. 1 257 54.519 T 28-03-2018 IPR023463 Electron transfer flavoprotein, FixA subunit GO:0009055|GO:0009437 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 Pfam PF01012 Electron transfer flavoprotein domain 28 210 9.9E-38 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 PIRSF PIRSF000090 1 256 2.1E-65 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 SMART SM00893 22 215 5.1E-38 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 159 179 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 SUPERFAMILY SSF52402 1 253 2.51E-59 T 28-03-2018 WM46_RS14625 7ffdc6d5a2f72a47cc4cf962169844d4 257 Gene3D G3DSA:3.40.50.620 1 255 8.4E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 Pfam PF01252 Signal peptidase (SPase) II 16 155 1.0E-36 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 101 116 1.8E-19 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 53 61 1.8E-19 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 137 153 1.8E-19 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 7 162 16.94 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 TIGRFAM TIGR00077 lspA: signal peptidase II 1 161 2.3E-59 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS14695 6bfb02f072784087e27daa829ec436ab 162 ProSitePatterns PS00855 Signal peptidases II signature. 104 116 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 Gene3D G3DSA:3.40.190.10 90 179 3.8E-12 T 28-03-2018 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 SUPERFAMILY SSF53850 92 295 3.98E-41 T 28-03-2018 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 9.4E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 Gene3D G3DSA:1.10.10.10 3 86 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 Gene3D G3DSA:3.40.190.10 180 267 1.9E-25 T 28-03-2018 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 Pfam PF03466 LysR substrate binding domain 91 294 3.1E-37 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 SUPERFAMILY SSF46785 4 82 1.95E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS11965 48f6d140c9221a16cc27d7fff6b73dd9 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS15180 82cc470170b83bf41aaa0a870726ea3a 482 Gene3D G3DSA:3.40.50.300 3 229 2.1E-25 T 28-03-2018 WM46_RS15180 82cc470170b83bf41aaa0a870726ea3a 482 SUPERFAMILY SSF52540 137 461 3.8E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15180 82cc470170b83bf41aaa0a870726ea3a 482 SUPERFAMILY SSF52540 5 103 3.8E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15180 82cc470170b83bf41aaa0a870726ea3a 482 Gene3D G3DSA:3.40.50.300 230 461 1.6E-18 T 28-03-2018 WM46_RS15180 82cc470170b83bf41aaa0a870726ea3a 482 Pfam PF13361 UvrD-like helicase C-terminal domain 326 459 1.2E-12 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM46_RS15180 82cc470170b83bf41aaa0a870726ea3a 482 Pfam PF13245 AAA domain 9 226 3.9E-12 T 28-03-2018 WM46_RS12510 bb66b38dfbb65fa6027576f4819309b7 350 Pfam PF04245 37-kD nucleoid-associated bacterial protein 96 311 1.1E-12 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 WM46_RS14740 f650d232bc1a390cbabac2bf304f3685 497 Pfam PF00884 Sulfatase 31 377 3.0E-71 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS14740 f650d232bc1a390cbabac2bf304f3685 497 SUPERFAMILY SSF53649 29 478 1.19E-124 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS14740 f650d232bc1a390cbabac2bf304f3685 497 Gene3D G3DSA:3.30.1120.10 409 486 3.3E-14 T 28-03-2018 WM46_RS14740 f650d232bc1a390cbabac2bf304f3685 497 Gene3D G3DSA:3.40.720.10 30 408 1.1E-90 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS14740 f650d232bc1a390cbabac2bf304f3685 497 ProSitePatterns PS00523 Sulfatases signature 1. 77 89 - T 28-03-2018 IPR024607 Sulfatase, conserved site WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 SUPERFAMILY SSF51430 7 276 3.4E-78 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 PIRSF PIRSF000097 115 283 1.7E-25 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 PIRSF PIRSF000097 1 122 2.8E-17 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 Pfam PF00248 Aldo/keto reductase family 17 271 7.0E-54 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 Gene3D G3DSA:3.20.20.100 2 284 8.3E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 PRINTS PR00069 Aldo-keto reductase signature 41 65 3.0E-18 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 PRINTS PR00069 Aldo-keto reductase signature 97 115 3.0E-18 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 PRINTS PR00069 Aldo-keto reductase signature 206 230 3.0E-18 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS08350 7420edbec8bd42e243a15372f9372b8d 284 PRINTS PR00069 Aldo-keto reductase signature 127 144 3.0E-18 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS02700 8be7b8cbef406de22661cd846259e7ba 423 Pfam PF03825 Nucleoside H+ symporter 1 404 3.3E-182 T 28-03-2018 WM46_RS02700 8be7b8cbef406de22661cd846259e7ba 423 SUPERFAMILY SSF103473 5 404 1.29E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS02700 8be7b8cbef406de22661cd846259e7ba 423 Gene3D G3DSA:1.20.1250.20 2 195 8.2E-16 T 28-03-2018 WM46_RS02700 8be7b8cbef406de22661cd846259e7ba 423 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 408 1.1E-191 T 28-03-2018 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 WM46_RS02700 8be7b8cbef406de22661cd846259e7ba 423 Gene3D G3DSA:1.20.1250.20 200 414 1.5E-22 T 28-03-2018 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 SUPERFAMILY SSF51735 317 651 1.34E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Pfam PF02911 Formyl transferase, C-terminal domain 202 294 4.9E-19 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 SUPERFAMILY SSF50486 204 303 8.16E-23 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Gene3D G3DSA:3.40.50.720 314 659 4.9E-49 T 28-03-2018 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Pfam PF00551 Formyl transferase 57 176 1.8E-24 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 SUPERFAMILY SSF53328 1 202 2.88E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Pfam PF01370 NAD dependent epimerase/dehydratase family 318 566 4.1E-45 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Hamap MF_01166 Bifunctional polymyxin resistance protein ArnA [arnA]. 1 660 65.088 T 28-03-2018 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 PIRSF PIRSF036506 1 660 0.0 T 28-03-2018 IPR021168 Bifunctional polymyxin resistance protein, ArnA GO:0016742|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00520+2.1.2.13+1.1.1.305|KEGG: 00650+1.1.1.30 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Gene3D G3DSA:3.40.50.170 1 202 1.6E-47 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS01900 e62d64f69d3dea45233b5a535e93d344 660 Gene3D G3DSA:3.10.25.10 203 305 1.0E-22 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 SMART SM00857 2 136 9.5E-62 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 Pfam PF00239 Resolvase, N terminal domain 3 135 2.8E-47 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 Pfam PF02796 Helix-turn-helix domain of resolvase 138 181 1.2E-9 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 Gene3D G3DSA:1.20.5.40 108 131 1.8E-18 T 28-03-2018 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 SUPERFAMILY SSF53041 1 135 2.09E-46 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 Gene3D G3DSA:3.40.50.1390 1 107 3.7E-35 T 28-03-2018 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 Gene3D G3DSA:1.10.260.40 168 185 0.0014 T 28-03-2018 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 Gene3D G3DSA:1.10.10.60 132 167 3.2E-12 T 28-03-2018 WM46_RS22535 7de3b3f044238dc1e6f334673e3cef04 185 SUPERFAMILY SSF46689 138 183 1.21E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 Pfam PF00267 Gram-negative porin 27 350 5.4E-146 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 94 104 1.8E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 305 322 1.8E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 151 162 1.8E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 227 239 1.8E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 1.8E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 ProSitePatterns PS00576 General diffusion Gram-negative porins signature. 305 321 - T 28-03-2018 IPR013793 Porin, Gram-negative type, conserved site WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 SUPERFAMILY SSF56935 22 350 5.49E-77 T 28-03-2018 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00183 E.coli/Salmonella-type porin signature 261 280 5.6E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00183 E.coli/Salmonella-type porin signature 233 250 5.6E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00183 E.coli/Salmonella-type porin signature 149 171 5.6E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 5.6E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 5.6E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 PRINTS PR00183 E.coli/Salmonella-type porin signature 94 116 5.6E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS13655 b14fe0bfbd03acfe5001f13abba596df 350 Gene3D G3DSA:2.40.160.10 32 350 1.6E-52 T 28-03-2018 WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 3.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 3.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 3.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 251 2.2E-60 T 28-03-2018 WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 9.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 9.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 9.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 Gene3D G3DSA:3.40.50.720 1 255 4.8E-70 T 28-03-2018 WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS23835 be0c35a014e5ae5b9f1c66a01c87408b 255 SUPERFAMILY SSF51735 4 253 4.32E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12345 66c47abf62c627d949616c50e0e46f9a 558 Gene3D G3DSA:1.20.91.10 239 320 1.6E-6 T 28-03-2018 WM46_RS12345 66c47abf62c627d949616c50e0e46f9a 558 SUPERFAMILY SSF51735 418 549 1.76E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12345 66c47abf62c627d949616c50e0e46f9a 558 Pfam PF02254 TrkA-N domain 421 534 3.7E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM46_RS12345 66c47abf62c627d949616c50e0e46f9a 558 Pfam PF00999 Sodium/hydrogen exchanger family 13 384 5.0E-78 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM46_RS12345 66c47abf62c627d949616c50e0e46f9a 558 Gene3D G3DSA:3.40.50.720 416 550 4.3E-17 T 28-03-2018 WM46_RS12345 66c47abf62c627d949616c50e0e46f9a 558 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 15 294 4.1E-76 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Gene3D G3DSA:3.40.50.620 411 647 1.3E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 859 23.275 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 SUPERFAMILY SSF50677 226 415 1.47E-56 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 618 651 9.7E-7 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 572 2.4E-7 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 171 1.4E-25 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Pfam PF08264 Anticodon-binding domain of tRNA 701 822 4.3E-16 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 859 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 403 1.1E-78 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Gene3D G3DSA:1.10.730.10 648 796 5.4E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Gene3D G3DSA:3.90.740.10 225 410 1.4E-53 T 28-03-2018 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 Gene3D G3DSA:3.40.50.620 32 194 5.4E-49 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 SUPERFAMILY SSF52374 416 668 1.21E-140 T 28-03-2018 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 SUPERFAMILY SSF52374 5 226 1.21E-140 T 28-03-2018 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 4.1E-52 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 WM46_RS11350 1603567777d5ba46b62b0b859f615415 860 SUPERFAMILY SSF47323 662 859 4.3E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 SUPERFAMILY SSF47384 243 320 2.55E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 SUPERFAMILY SSF55874 327 477 4.58E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 SMART SM00387 367 479 3.0E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 1.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 1.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 1.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.7E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 257 320 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 Gene3D G3DSA:3.30.565.10 327 483 7.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 478 1.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 SMART SM00388 256 324 4.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS00480 dadf44118e0f412820209091e2f0e217 483 Gene3D G3DSA:1.10.287.130 246 320 1.4E-13 T 28-03-2018 WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 Pfam PF17151 Periplasmic sensor domain 41 226 1.7E-82 T 28-03-2018 IPR033416 Periplasmic sensor domain CHASE7 WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 Gene3D G3DSA:3.30.70.270 391 564 2.0E-54 T 28-03-2018 WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 SMART SM00267 387 561 2.4E-68 T 28-03-2018 IPR000160 GGDEF domain WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 Gene3D G3DSA:3.30.450.20 233 349 6.6E-5 T 28-03-2018 WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 394 561 9.4E-62 T 28-03-2018 IPR000160 GGDEF domain WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 Pfam PF00990 Diguanylate cyclase, GGDEF domain 398 557 3.3E-48 T 28-03-2018 IPR000160 GGDEF domain WM46_RS03750 ebc501f08bd2e38e6af9a70858633de3 564 SUPERFAMILY SSF55073 403 562 1.57E-46 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS06800 ca8be3fcea6a3db6b9b649a285914ade 200 Gene3D G3DSA:3.90.80.10 21 200 6.8E-47 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS06800 ca8be3fcea6a3db6b9b649a285914ade 200 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 34 194 30.299 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS06800 ca8be3fcea6a3db6b9b649a285914ade 200 Pfam PF00719 Inorganic pyrophosphatase 38 194 4.3E-45 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS06800 ca8be3fcea6a3db6b9b649a285914ade 200 SUPERFAMILY SSF50324 29 194 1.03E-52 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS06800 ca8be3fcea6a3db6b9b649a285914ade 200 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 85 91 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 Gene3D G3DSA:1.20.120.530 84 229 3.1E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 68 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 SMART SM00895 97 220 2.3E-16 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 Gene3D G3DSA:1.10.10.10 2 70 3.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 SUPERFAMILY SSF48008 98 227 2.14E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 SUPERFAMILY SSF46785 4 72 1.86E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 4.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 4.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 Pfam PF07729 FCD domain 99 218 2.5E-24 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS19675 2bb6f5c663e00fe596cfb5a053ae5c16 229 SMART SM00345 9 68 3.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 6.2E-172 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 SUPERFAMILY SSF52540 4 50 4.92E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 SUPERFAMILY SSF52540 284 506 4.92E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 PIRSF PIRSF003128 1 553 2.7E-159 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 Gene3D G3DSA:3.40.50.300 232 526 7.8E-19 T 28-03-2018 WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 SUPERFAMILY SSF52540 1 217 2.58E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 510 3.1E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal WM46_RS00155 fac4ad501039c8ec68bb639ee32d10f3 553 Gene3D G3DSA:3.40.50.300 1 231 1.2E-25 T 28-03-2018 WM46_RS20360 cbb80d5470fb6737bfd836a735bde787 463 Pfam PF03841 L-seryl-tRNA selenium transferase 83 451 1.7E-176 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 WM46_RS20360 cbb80d5470fb6737bfd836a735bde787 463 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 10 461 2.5E-189 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 WM46_RS20360 cbb80d5470fb6737bfd836a735bde787 463 SUPERFAMILY SSF53383 74 461 2.21E-47 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS20360 cbb80d5470fb6737bfd836a735bde787 463 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 463 254.642 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 WM46_RS20360 cbb80d5470fb6737bfd836a735bde787 463 Gene3D G3DSA:3.40.640.10 102 346 1.1E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS20360 cbb80d5470fb6737bfd836a735bde787 463 Pfam PF12390 Selenocysteine synthase N terminal 9 48 4.8E-9 T 28-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 Pfam PF00232 Glycosyl hydrolase family 1 5 474 4.0E-131 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 SUPERFAMILY SSF51445 2 470 3.63E-165 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 Gene3D G3DSA:3.20.20.80 3 477 1.0E-153 T 28-03-2018 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS24220 47c2d589427795cd29e48b63da8945c2 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS09500 c94247299d175ad4ce251ed2a266b9fa 130 SUPERFAMILY SSF54593 2 127 4.13E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS09500 c94247299d175ad4ce251ed2a266b9fa 130 Gene3D G3DSA:3.10.180.10 1 129 6.2E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS13105 321e54bdff5ef5be03fa8044d01ccb81 434 Pfam PF07690 Major Facilitator Superfamily 25 385 7.4E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS13105 321e54bdff5ef5be03fa8044d01ccb81 434 SUPERFAMILY SSF103473 10 419 2.09E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS13105 321e54bdff5ef5be03fa8044d01ccb81 434 Gene3D G3DSA:1.20.1250.20 228 434 1.9E-24 T 28-03-2018 WM46_RS13105 321e54bdff5ef5be03fa8044d01ccb81 434 PIRSF PIRSF002808 3 434 9.5E-121 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS13105 321e54bdff5ef5be03fa8044d01ccb81 434 Gene3D G3DSA:1.20.1250.20 8 205 5.7E-33 T 28-03-2018 WM46_RS14820 89997c2e2263a0e59024b88f84de58f6 228 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 225 2.0E-75 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS14820 89997c2e2263a0e59024b88f84de58f6 228 Gene3D G3DSA:3.40.1280.10 2 164 3.7E-33 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS14820 89997c2e2263a0e59024b88f84de58f6 228 PIRSF PIRSF004808 1 228 1.5E-62 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS14820 89997c2e2263a0e59024b88f84de58f6 228 SUPERFAMILY SSF75217 2 156 1.9E-30 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS14820 89997c2e2263a0e59024b88f84de58f6 228 Pfam PF00588 SpoU rRNA Methylase family 3 153 2.2E-32 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 SUPERFAMILY SSF52540 298 523 3.23E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 Pfam PF00005 ABC transporter 336 467 2.9E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 Pfam PF00005 ABC transporter 18 184 4.8E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 Gene3D G3DSA:3.40.50.300 3 282 2.7E-51 T 28-03-2018 WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 SUPERFAMILY SSF52540 6 237 7.14E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 SMART SM00382 344 512 5.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 SMART SM00382 26 228 4.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 Gene3D G3DSA:3.40.50.300 283 531 6.3E-49 T 28-03-2018 WM46_RS10350 bd3c4647b72dfc08fac947927b3849d0 531 Pfam PF12848 ABC transporter 224 309 1.8E-20 T 28-03-2018 IPR032781 ABC-transporter extension domain WM46_RS05650 21727a8c948a9e3d951add8861cb0db7 225 Pfam PF02665 Nitrate reductase gamma subunit 5 224 2.9E-80 T 28-03-2018 IPR023234 NarG-like domain WM46_RS05650 21727a8c948a9e3d951add8861cb0db7 225 SUPERFAMILY SSF103501 1 224 2.09E-70 T 28-03-2018 IPR023234 NarG-like domain WM46_RS05650 21727a8c948a9e3d951add8861cb0db7 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 225 2.9E-124 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS05650 21727a8c948a9e3d951add8861cb0db7 225 Gene3D G3DSA:1.20.950.20 1 216 1.9E-42 T 28-03-2018 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 SUPERFAMILY SSF52540 141 385 3.04E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Pfam PF00072 Response regulator receiver domain 8 117 1.6E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Pfam PF00158 Sigma-54 interaction domain 141 308 2.3E-72 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Gene3D G3DSA:3.40.50.2300 3 146 8.2E-39 T 28-03-2018 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 441 2.9E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 408 425 2.9E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS21290 3891043298373a835a572cfe8e74c245 441 SUPERFAMILY SSF46689 393 440 5.97E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Gene3D G3DSA:1.10.8.60 314 404 1.5E-26 T 28-03-2018 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Gene3D G3DSA:3.40.50.300 147 313 8.7E-31 T 28-03-2018 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 SMART SM00382 161 304 3.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21290 3891043298373a835a572cfe8e74c245 441 SMART SM00448 6 117 3.1E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Gene3D G3DSA:1.10.10.60 405 441 2.8E-16 T 28-03-2018 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 Pfam PF02954 Bacterial regulatory protein, Fis family 403 441 3.7E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS21290 3891043298373a835a572cfe8e74c245 441 SUPERFAMILY SSF52172 5 184 4.13E-48 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS13450 4ce5c495a9e472c52d34c4f5486d7fe2 255 SUPERFAMILY SSF52540 3 228 7.56E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13450 4ce5c495a9e472c52d34c4f5486d7fe2 255 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS13450 4ce5c495a9e472c52d34c4f5486d7fe2 255 Pfam PF00005 ABC transporter 18 166 3.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS13450 4ce5c495a9e472c52d34c4f5486d7fe2 255 Gene3D G3DSA:3.40.50.300 1 238 2.2E-64 T 28-03-2018 WM46_RS13450 4ce5c495a9e472c52d34c4f5486d7fe2 255 SMART SM00382 27 215 2.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS13200 ea2810af674dda4732b439605f7a5961 210 PIRSF PIRSF006324 1 207 1.6E-50 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS13200 ea2810af674dda4732b439605f7a5961 210 Pfam PF01810 LysE type translocator 17 206 8.2E-53 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS13200 ea2810af674dda4732b439605f7a5961 210 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 20 202 5.7E-70 T 28-03-2018 IPR004778 Homoserine/Threonine efflux protein GO:0016021 WM46_RS19565 346d49298942261d84d604122ae5b4bf 257 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 11 257 3.1E-121 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 WM46_RS19565 346d49298942261d84d604122ae5b4bf 257 Pfam PF00005 ABC transporter 26 181 1.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS19565 346d49298942261d84d604122ae5b4bf 257 SMART SM00382 35 237 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19565 346d49298942261d84d604122ae5b4bf 257 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS19565 346d49298942261d84d604122ae5b4bf 257 Gene3D G3DSA:3.40.50.300 9 255 1.1E-63 T 28-03-2018 WM46_RS19565 346d49298942261d84d604122ae5b4bf 257 SUPERFAMILY SSF52540 11 243 8.47E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10535 6ef1d9c4172c1e32228c9aa8a479fb40 234 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 230 2.8E-59 T 28-03-2018 IPR006214 Bax inhibitor 1-related WM46_RS02530 e108ab072a9148aa39b6ecae348f7191 312 Pfam PF01207 Dihydrouridine synthase (Dus) 5 302 9.1E-92 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS02530 e108ab072a9148aa39b6ecae348f7191 312 Gene3D G3DSA:3.20.20.70 1 242 5.3E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS02530 e108ab072a9148aa39b6ecae348f7191 312 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS02530 e108ab072a9148aa39b6ecae348f7191 312 SUPERFAMILY SSF51395 1 301 3.48E-72 T 28-03-2018 WM46_RS02530 e108ab072a9148aa39b6ecae348f7191 312 PIRSF PIRSF006621 1 312 2.0E-82 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 WM46_RS02530 e108ab072a9148aa39b6ecae348f7191 312 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 310 52.297 T 28-03-2018 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 WM46_RS02365 e2cfc9eda9561dd885f661382f3b4fc2 393 Gene3D G3DSA:1.20.1250.20 212 391 1.5E-22 T 28-03-2018 WM46_RS02365 e2cfc9eda9561dd885f661382f3b4fc2 393 TIGRFAM TIGR00899 2A0120: sugar efflux transporter 19 392 8.2E-190 T 28-03-2018 IPR004750 Sugar efflux GO:0008643|GO:0015542|GO:0016021 WM46_RS02365 e2cfc9eda9561dd885f661382f3b4fc2 393 Pfam PF07690 Major Facilitator Superfamily 21 356 1.3E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS02365 e2cfc9eda9561dd885f661382f3b4fc2 393 Gene3D G3DSA:1.20.1250.20 6 209 4.3E-19 T 28-03-2018 WM46_RS02365 e2cfc9eda9561dd885f661382f3b4fc2 393 SUPERFAMILY SSF103473 19 390 3.01E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 SMART SM00354 1 71 1.9E-34 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 SUPERFAMILY SSF53822 60 332 1.13E-90 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 SUPERFAMILY SSF47413 2 59 1.77E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 Gene3D G3DSA:3.40.50.2300 55 178 1.8E-30 T 28-03-2018 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 Pfam PF13377 Periplasmic binding protein-like domain 171 332 3.0E-42 T 28-03-2018 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 Gene3D G3DSA:3.40.50.2300 179 309 1.2E-48 T 28-03-2018 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.3E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.0E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19415 a46a86d24d38d27e74f08c914e31ed94 332 Gene3D G3DSA:1.10.260.40 2 54 1.7E-20 T 28-03-2018 WM46_RS10730 808cc71fd571c0be2b0c61625e1a0dc4 254 Gene3D G3DSA:3.40.50.300 2 243 3.0E-51 T 28-03-2018 WM46_RS10730 808cc71fd571c0be2b0c61625e1a0dc4 254 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10730 808cc71fd571c0be2b0c61625e1a0dc4 254 Pfam PF00005 ABC transporter 26 160 8.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10730 808cc71fd571c0be2b0c61625e1a0dc4 254 SMART SM00382 29 210 1.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10730 808cc71fd571c0be2b0c61625e1a0dc4 254 SUPERFAMILY SSF52540 5 228 4.19E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 1.1E-7 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.1E-7 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.1E-7 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.6E-6 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 2.6E-6 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 2.6E-6 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Pfam PF02540 NAD synthase 217 259 4.8E-7 T 28-03-2018 IPR022310 NAD/GMP synthase WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 3.2E-84 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 212 525 1.3E-156 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 SUPERFAMILY SSF54810 405 525 7.98E-51 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 SUPERFAMILY SSF52402 197 420 3.09E-59 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 SUPERFAMILY SSF52317 5 204 3.64E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Gene3D G3DSA:3.40.50.620 223 400 1.8E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Pfam PF00117 Glutamine amidotransferase class-I 12 199 2.7E-41 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Pfam PF00958 GMP synthase C terminal domain 433 524 3.0E-43 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 9.4E-7 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 9.4E-7 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 9.4E-7 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 56.353 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Gene3D G3DSA:3.30.300.10 401 525 1.5E-52 T 28-03-2018 WM46_RS00745 1d1b9820ecf43a7d17faaf6919f664a1 525 Gene3D G3DSA:3.40.50.880 5 222 3.7E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 SUPERFAMILY SSF51905 3 301 6.48E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 Gene3D G3DSA:3.50.50.60 102 237 2.0E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 278 2.8E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.9E-20 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.9E-20 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 1.9E-20 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.9E-20 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.9E-20 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 3.8E-14 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 3.8E-14 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 3.8E-14 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.8E-14 T 28-03-2018 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 Hamap MF_01313 Nitric oxide reductase FlRd-NAD(+) reductase [norW]. 1 377 56.406 T 28-03-2018 IPR023961 Nitric oxide reductase FlRd-NAD(+) reductase GO:0016731|GO:0055114 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 Gene3D G3DSA:3.50.50.60 2 101 2.4E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25460 23ddab6eb9d793a9130f70854e4242f0 377 Gene3D G3DSA:3.50.50.60 239 302 4.6E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08105 13d296a5e644c007295db80e81177915 463 Pfam PF00375 Sodium:dicarboxylate symporter family 29 443 2.7E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 Gene3D G3DSA:1.10.3860.10 19 450 5.1E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 PRINTS PR00173 Glutamate-aspartate symporter signature 75 95 3.4E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 PRINTS PR00173 Glutamate-aspartate symporter signature 27 47 3.4E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 PRINTS PR00173 Glutamate-aspartate symporter signature 182 204 3.4E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 3.4E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 3.4E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 3.4E-27 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08105 13d296a5e644c007295db80e81177915 463 SUPERFAMILY SSF118215 29 443 1.1E-97 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 SUPERFAMILY SSF56059 1 238 1.06E-81 T 28-03-2018 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 Pfam PF00549 CoA-ligase 262 382 1.1E-24 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 Pfam PF08442 ATP-grasp domain 2 203 1.6E-83 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 PIRSF PIRSF001554 1 388 1.2E-154 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 Gene3D G3DSA:3.30.470.20 96 239 8.2E-52 T 28-03-2018 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 Gene3D G3DSA:3.40.50.261 240 385 2.5E-42 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.0E-184 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.501 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 Gene3D G3DSA:3.30.1490.20 21 95 1.7E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS10975 b30d7fec8447596cb9d5bbdc16344e33 388 SUPERFAMILY SSF52210 239 385 3.66E-53 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS11745 5f4bad6066393e72b7b2c4f0d055e981 541 SUPERFAMILY SSF81296 145 270 1.03E-31 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS11745 5f4bad6066393e72b7b2c4f0d055e981 541 Pfam PF00756 Putative esterase 297 515 1.1E-25 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 WM46_RS11745 5f4bad6066393e72b7b2c4f0d055e981 541 SUPERFAMILY SSF53474 282 514 6.05E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11745 5f4bad6066393e72b7b2c4f0d055e981 541 Pfam PF11806 Domain of unknown function (DUF3327) 172 258 2.1E-15 T 28-03-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 WM46_RS11745 5f4bad6066393e72b7b2c4f0d055e981 541 Gene3D G3DSA:3.40.50.1820 272 524 9.0E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11745 5f4bad6066393e72b7b2c4f0d055e981 541 Gene3D G3DSA:2.60.40.10 143 261 2.4E-32 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS14525 f668778e19f3107562ef09003918ad73 231 Gene3D G3DSA:3.40.225.10 1 231 1.7E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS14525 f668778e19f3107562ef09003918ad73 231 SMART SM01007 7 198 1.6E-71 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS14525 f668778e19f3107562ef09003918ad73 231 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 3.5E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS14525 f668778e19f3107562ef09003918ad73 231 Hamap MF_00989 L-ribulose-5-phosphate 4-epimerase [araD]. 1 231 75.73 T 28-03-2018 IPR033748 L-ribulose-5-phosphate 4-epimerase AraD GO:0008742|GO:0019569 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 WM46_RS14525 f668778e19f3107562ef09003918ad73 231 SUPERFAMILY SSF53639 1 223 1.61E-71 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS14525 f668778e19f3107562ef09003918ad73 231 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 1 231 7.7E-135 T 28-03-2018 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 WM46_RS18495 9bd107aebc8dd66cf25459f2c0fe1a34 251 Hamap MF_00319 CDP-diacylglycerol pyrophosphatase [cdh]. 1 249 52.004 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 WM46_RS18495 9bd107aebc8dd66cf25459f2c0fe1a34 251 SUPERFAMILY SSF54197 29 247 3.49E-89 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS18495 9bd107aebc8dd66cf25459f2c0fe1a34 251 PIRSF PIRSF001273 1 251 6.5E-104 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 WM46_RS18495 9bd107aebc8dd66cf25459f2c0fe1a34 251 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 29 247 5.3E-91 T 28-03-2018 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 WM46_RS18495 9bd107aebc8dd66cf25459f2c0fe1a34 251 Gene3D G3DSA:3.30.428.30 27 247 1.5E-90 T 28-03-2018 WM46_RS18495 9bd107aebc8dd66cf25459f2c0fe1a34 251 TIGRFAM TIGR00672 cdh: CDP-diacylglycerol diphosphatase 1 248 1.4E-144 T 28-03-2018 IPR015993 CDP-diacylglycerol pyrophosphatase, proteobacterial GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 WM46_RS04025 2681102e722fdb16535fab45b35006ce 79 Pfam PF10678 Protein of unknown function (DUF2492) 3 78 6.0E-35 T 28-03-2018 IPR019620 Putative metal-binding protein WM46_RS04025 2681102e722fdb16535fab45b35006ce 79 TIGRFAM TIGR03853 matur_matur: putative metal-binding protein 3 79 1.1E-34 T 28-03-2018 IPR019620 Putative metal-binding protein WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 SMART SM00487 195 390 2.8E-18 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 Hamap MF_00983 Probable primosomal protein N' [priA]. 6 732 26.12 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 SUPERFAMILY SSF52540 215 440 5.89E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 SUPERFAMILY SSF52540 503 601 5.89E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 SMART SM00490 492 589 1.1E-8 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 Gene3D G3DSA:3.40.50.300 196 361 4.9E-27 T 28-03-2018 WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 Gene3D G3DSA:3.40.50.300 399 631 1.1E-22 T 28-03-2018 WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 TIGRFAM TIGR00595 priA: primosomal protein N' 221 730 1.6E-216 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 Pfam PF00270 DEAD/DEAH box helicase 203 362 3.6E-15 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS18385 4abe8fd9f039f02e0031e572df341195 732 Pfam PF00271 Helicase conserved C-terminal domain 522 589 2.5E-5 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 Gene3D G3DSA:3.40.190.10 94 182 7.9E-14 T 28-03-2018 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 SUPERFAMILY SSF53850 96 288 1.81E-28 T 28-03-2018 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 SUPERFAMILY SSF46785 11 119 2.12E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 2.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 2.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 2.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 Gene3D G3DSA:3.40.190.10 183 262 7.3E-16 T 28-03-2018 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 7.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 Gene3D G3DSA:1.10.10.10 9 93 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01755 671f6cac3d4d65498b0229fe3fc59a10 312 Pfam PF03466 LysR substrate binding domain 97 272 1.2E-27 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 8 794 0.0 T 28-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 Gene3D G3DSA:3.40.50.2000 8 459 1.7E-169 T 28-03-2018 WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 PIRSF PIRSF000460 1 797 1.7E-204 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 SUPERFAMILY SSF53756 6 795 1.81E-293 T 28-03-2018 WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 Pfam PF00343 Carbohydrate phosphorylase 93 794 0.0 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 Gene3D G3DSA:3.40.50.2000 460 780 1.9E-134 T 28-03-2018 WM46_RS17920 5964e0f6bba9e2845e0880018e3c34c9 797 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 638 650 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS04095 fbe2e98f2d0ba0a91c192390d47e344f 473 Pfam PF00982 Glycosyltransferase family 20 16 451 4.9E-145 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 WM46_RS04095 fbe2e98f2d0ba0a91c192390d47e344f 473 Gene3D G3DSA:3.40.50.2000 236 436 1.8E-40 T 28-03-2018 WM46_RS04095 fbe2e98f2d0ba0a91c192390d47e344f 473 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 451 1.0E-179 T 28-03-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 WM46_RS04095 fbe2e98f2d0ba0a91c192390d47e344f 473 SUPERFAMILY SSF53756 2 453 3.14E-145 T 28-03-2018 WM46_RS04095 fbe2e98f2d0ba0a91c192390d47e344f 473 Gene3D G3DSA:3.40.50.2000 1 235 1.4E-68 T 28-03-2018 WM46_RS24050 3561b5bf462b3f1353796a257ac3e21e 148 Gene3D G3DSA:3.40.630.30 1 148 1.4E-33 T 28-03-2018 WM46_RS24050 3561b5bf462b3f1353796a257ac3e21e 148 Pfam PF00583 Acetyltransferase (GNAT) family 18 120 1.6E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS24050 3561b5bf462b3f1353796a257ac3e21e 148 SUPERFAMILY SSF55729 3 146 1.03E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS24050 3561b5bf462b3f1353796a257ac3e21e 148 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 142 1.5E-45 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 Pfam PF08212 Lipocalin-like domain 35 174 2.6E-46 T 28-03-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 ProSitePatterns PS00213 Lipocalin signature. 33 46 - T 28-03-2018 IPR022272 Lipocalin family conserved site WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 SUPERFAMILY SSF50814 12 176 7.48E-49 T 28-03-2018 IPR012674 Calycin WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 Gene3D G3DSA:2.40.128.20 2 177 1.9E-45 T 28-03-2018 IPR012674 Calycin WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 104 118 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 163 173 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 121 129 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 136 147 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 51 67 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 34 48 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PRINTS PR01171 Bacterial lipocalin signature 70 79 1.5E-49 T 28-03-2018 IPR002446 Lipocalin, bacterial GO:0005215 WM46_RS22790 43afcdb2dcdf0383d7c820b687c103be 177 PIRSF PIRSF036893 1 177 4.1E-53 T 28-03-2018 IPR022271 Lipocalin, ApoD type WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PRINTS PR00471 Acetate kinase family signature 6 17 7.1E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PRINTS PR00471 Acetate kinase family signature 325 341 7.1E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PRINTS PR00471 Acetate kinase family signature 302 315 7.1E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PRINTS PR00471 Acetate kinase family signature 176 189 7.1E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PRINTS PR00471 Acetate kinase family signature 206 227 7.1E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PRINTS PR00471 Acetate kinase family signature 380 392 7.1E-48 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 Gene3D G3DSA:3.30.420.40 5 198 2.6E-66 T 28-03-2018 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 PIRSF PIRSF000722 2 400 1.5E-142 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 TIGRFAM TIGR00016 ackA: acetate kinase 1 399 1.3E-186 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 Hamap MF_00020 Acetate kinase [ackA]. 1 400 185.377 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 SUPERFAMILY SSF53067 160 398 6.66E-84 T 28-03-2018 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 Pfam PF00871 Acetokinase family 6 393 1.2E-177 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 SUPERFAMILY SSF53067 4 199 4.14E-62 T 28-03-2018 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 Gene3D G3DSA:3.30.420.40 199 400 8.0E-77 T 28-03-2018 WM46_RS01720 a427c718bc5a4182c6c77d48420c92d4 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 206 223 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 482 1.0E-60 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 SUPERFAMILY SSF47170 25 180 3.79E-44 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 SMART SM00304 214 266 2.5E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 Gene3D G3DSA:1.20.120.30 38 174 6.7E-36 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 SMART SM00283 267 514 4.5E-95 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 189 209 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 60 75 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 6.5E-90 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 SUPERFAMILY SSF58104 234 517 2.22E-76 T 28-03-2018 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 Pfam PF02203 Tar ligand binding domain homologue 1 173 7.9E-47 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 SMART SM00319 44 180 1.7E-43 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 Pfam PF00672 HAMP domain 215 263 3.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 Gene3D G3DSA:1.10.287.950 220 318 1.9E-13 T 28-03-2018 WM46_RS04165 ab8353e776a90b3af9d2fea2eefccb05 553 Gene3D G3DSA:1.10.287.950 319 518 2.2E-48 T 28-03-2018 WM46_RS12935 006e6345bd1f3fa7e5a91c3efc5f2e30 302 Gene3D G3DSA:3.30.420.40 116 302 5.2E-50 T 28-03-2018 WM46_RS12935 006e6345bd1f3fa7e5a91c3efc5f2e30 302 ProSitePatterns PS01125 ROK family signature. 130 157 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS12935 006e6345bd1f3fa7e5a91c3efc5f2e30 302 Pfam PF00480 ROK family 3 301 3.4E-94 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS12935 006e6345bd1f3fa7e5a91c3efc5f2e30 302 SUPERFAMILY SSF53067 3 300 1.73E-61 T 28-03-2018 WM46_RS12935 006e6345bd1f3fa7e5a91c3efc5f2e30 302 Gene3D G3DSA:3.30.420.40 1 115 2.6E-24 T 28-03-2018 WM46_RS08210 5f45177cbf7c2fb0d104ce4da6c23dd0 387 SUPERFAMILY SSF53850 31 384 2.96E-35 T 28-03-2018 WM46_RS08210 5f45177cbf7c2fb0d104ce4da6c23dd0 387 Pfam PF13416 Bacterial extracellular solute-binding protein 59 351 8.4E-21 T 28-03-2018 WM46_RS08210 5f45177cbf7c2fb0d104ce4da6c23dd0 387 Gene3D G3DSA:3.40.190.10 33 164 1.1E-5 T 28-03-2018 WM46_RS08210 5f45177cbf7c2fb0d104ce4da6c23dd0 387 Gene3D G3DSA:3.40.190.10 165 328 1.0E-15 T 28-03-2018 WM46_RS08210 5f45177cbf7c2fb0d104ce4da6c23dd0 387 PIRSF PIRSF029172 1 387 5.4E-175 T 28-03-2018 IPR027020 Protein ynjB WM46_RS19470 4f18c647f52e25756678abae7bb9d4ad 147 Pfam PF00258 Flavodoxin 7 138 3.8E-22 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS19470 4f18c647f52e25756678abae7bb9d4ad 147 SUPERFAMILY SSF52218 1 146 4.39E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS19470 4f18c647f52e25756678abae7bb9d4ad 147 Gene3D G3DSA:3.40.50.360 1 147 1.4E-28 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS04170 8f3f009691f4c598c354a58273215553 533 Pfam PF00672 HAMP domain 214 261 9.7E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 SMART SM00283 265 512 3.0E-97 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 SMART SM00304 212 264 2.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 SUPERFAMILY SSF58104 232 513 3.79E-74 T 28-03-2018 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 SMART SM00319 44 178 1.1E-39 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 480 1.9E-54 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 Gene3D G3DSA:1.10.287.950 241 316 3.8E-10 T 28-03-2018 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 188 208 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 53 68 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 2.0E-77 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 Gene3D G3DSA:1.10.287.950 317 516 1.0E-51 T 28-03-2018 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 Gene3D G3DSA:1.20.120.30 38 172 8.5E-27 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain WM46_RS04170 8f3f009691f4c598c354a58273215553 533 Pfam PF02203 Tar ligand binding domain homologue 1 168 4.8E-46 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 SUPERFAMILY SSF47170 25 173 7.59E-34 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS04170 8f3f009691f4c598c354a58273215553 533 ProSitePatterns PS00538 Bacterial chemotaxis sensory transducers signature. 290 312 - T 28-03-2018 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site WM46_RS04010 d7d5632918a927d3c141a2c49ed564a1 99 Pfam PF15941 FidL-like putative membrane protein 20 96 8.2E-8 T 28-03-2018 IPR031854 Putative membrane protein FidL-like WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 236 255 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 255 274 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 274 293 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 81 102 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 126 149 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PRINTS PR00714 Phosphomannose isomerase type I signature 220 235 2.1E-73 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 Gene3D G3DSA:1.10.441.10 162 262 8.2E-29 T 28-03-2018 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 Gene3D G3DSA:2.60.120.10 294 391 2.3E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 126 134 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 381 2.6E-130 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 PIRSF PIRSF001480 1 391 3.7E-109 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 Pfam PF01238 Phosphomannose isomerase type I 1 356 2.4E-112 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 SUPERFAMILY SSF51182 1 374 9.77E-101 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 255 280 - T 28-03-2018 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 WM46_RS07385 420741eb8e28573ce856fca2c864b2f3 391 Gene3D G3DSA:2.60.120.10 5 161 2.3E-51 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS01050 e5a9d881155ddf110e89e56bfdd5c4c6 149 Pfam PF11143 Protein of unknown function (DUF2919) 6 145 2.7E-46 T 28-03-2018 IPR021318 Protein of unknown function DUF2919 WM46_RS20050 67770c2175a3af9865f3cc8dfce6ceac 520 Gene3D G3DSA:3.30.1360.60 442 517 7.8E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS20050 67770c2175a3af9865f3cc8dfce6ceac 520 Pfam PF02378 Phosphotransferase system, EIIC 17 350 5.5E-58 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS20050 67770c2175a3af9865f3cc8dfce6ceac 520 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 411 503 9.5E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS20050 67770c2175a3af9865f3cc8dfce6ceac 520 Pfam PF00367 phosphotransferase system, EIIB 447 479 6.1E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS20050 67770c2175a3af9865f3cc8dfce6ceac 520 SUPERFAMILY SSF55604 444 516 3.79E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 Pfam PF00085 Thioredoxin 5 106 2.0E-34 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 SUPERFAMILY SSF52833 2 108 1.04E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS19270 850143d49315e8891aad60bd107000ef 109 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 PIRSF PIRSF000077 2 108 1.4E-45 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 Gene3D G3DSA:3.40.30.10 1 109 6.2E-36 T 28-03-2018 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 PRINTS PR00421 Thioredoxin family signature 24 32 3.8E-10 T 28-03-2018 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 PRINTS PR00421 Thioredoxin family signature 72 83 3.8E-10 T 28-03-2018 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 PRINTS PR00421 Thioredoxin family signature 32 41 3.8E-10 T 28-03-2018 WM46_RS19270 850143d49315e8891aad60bd107000ef 109 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 2.1E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 Pfam PF07690 Major Facilitator Superfamily 26 286 3.0E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 Gene3D G3DSA:1.20.1250.20 267 466 1.3E-19 T 28-03-2018 WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 SUPERFAMILY SSF103473 267 452 1.83E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 SUPERFAMILY SSF103473 8 203 1.83E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 Gene3D G3DSA:1.20.1250.20 11 209 4.0E-35 T 28-03-2018 WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 Hamap MF_01238 Putative sialic acid transporter [nanT]. 1 488 54.769 T 28-03-2018 IPR004742 Sialic acid transporter GO:0015144|GO:0016021|GO:0034219 WM46_RS17010 1aa13acf041cb35b34682f1cec1f4aa2 496 TIGRFAM TIGR00891 2A0112: MFS transporter, sialate:H+ symporter (SHS) family 9 442 1.0E-188 T 28-03-2018 IPR004742 Sialic acid transporter GO:0015144|GO:0016021|GO:0034219 WM46_RS19995 6463566574d17ad70378bf514d068f93 211 Gene3D G3DSA:1.10.10.10 141 210 2.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19995 6463566574d17ad70378bf514d068f93 211 SUPERFAMILY SSF46894 145 193 2.41E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS00730 36adfc3dae47aaeb433ace7c7df7cf15 73 ProDom PD060428 YFGJ CYTOPLASMIC VP0614 ECS3372 VC0765 YPO2873 Y1359 STY2763A VV0773 1 70 2.0E-27 T 28-03-2018 IPR010807 Protein of unknown function DUF1407 WM46_RS00730 36adfc3dae47aaeb433ace7c7df7cf15 73 Pfam PF07191 zinc-ribbons 4 68 9.3E-30 T 28-03-2018 IPR010807 Protein of unknown function DUF1407 WM46_RS00730 36adfc3dae47aaeb433ace7c7df7cf15 73 Gene3D G3DSA:2.20.25.10 3 32 0.076 T 28-03-2018 WM46_RS00730 36adfc3dae47aaeb433ace7c7df7cf15 73 Gene3D G3DSA:2.20.25.10 33 67 0.29 T 28-03-2018 WM46_RS00730 36adfc3dae47aaeb433ace7c7df7cf15 73 SUPERFAMILY SSF161187 1 69 1.44E-29 T 28-03-2018 IPR029037 YfgJ-like WM46_RS21850 e97fd9711e2897b9939bef4bf05c0d13 228 SUPERFAMILY SSF52540 3 225 6.02E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21850 e97fd9711e2897b9939bef4bf05c0d13 228 Gene3D G3DSA:3.40.50.300 1 226 4.6E-46 T 28-03-2018 WM46_RS21850 e97fd9711e2897b9939bef4bf05c0d13 228 Pfam PF00005 ABC transporter 26 180 8.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21850 e97fd9711e2897b9939bef4bf05c0d13 228 SMART SM00382 35 218 1.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21850 e97fd9711e2897b9939bef4bf05c0d13 228 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 4 220 3.2E-109 T 28-03-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS21850 e97fd9711e2897b9939bef4bf05c0d13 228 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 242 4.7E-29 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 357 47.129 T 28-03-2018 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 SUPERFAMILY SSF52283 4 109 2.34E-18 T 28-03-2018 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 119 146 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 Gene3D G3DSA:3.40.50.720 1 104 3.2E-22 T 28-03-2018 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 Gene3D G3DSA:3.40.50.720 105 257 1.9E-28 T 28-03-2018 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 282 9.1E-19 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 SUPERFAMILY SSF51735 91 243 7.68E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 197 213 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS01560 034d06f71eee5fafb8d9575dacebfbd1 378 Pfam PF11890 Domain of unknown function (DUF3410) 289 369 1.3E-27 T 28-03-2018 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181 WM46_RS18810 2c473c9f4b20596cc79fed7f188be4ac 462 Pfam PF13347 MFS/sugar transport protein 20 443 8.4E-83 T 28-03-2018 WM46_RS18810 2c473c9f4b20596cc79fed7f188be4ac 462 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 18 456 5.5E-157 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS18810 2c473c9f4b20596cc79fed7f188be4ac 462 Gene3D G3DSA:1.20.1250.20 228 443 1.7E-17 T 28-03-2018 WM46_RS18810 2c473c9f4b20596cc79fed7f188be4ac 462 SUPERFAMILY SSF103473 20 441 4.32E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS18810 2c473c9f4b20596cc79fed7f188be4ac 462 Gene3D G3DSA:1.20.1250.20 19 218 4.7E-9 T 28-03-2018 WM46_RS17895 b7335d376eaa30df1a487a13da7d5aaa 256 SUPERFAMILY SSF53474 4 250 8.72E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS17895 b7335d376eaa30df1a487a13da7d5aaa 256 Pfam PF00561 alpha/beta hydrolase fold 15 242 1.6E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS17895 b7335d376eaa30df1a487a13da7d5aaa 256 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 10 252 2.8E-115 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 WM46_RS17895 b7335d376eaa30df1a487a13da7d5aaa 256 Gene3D G3DSA:3.40.50.1820 2 255 2.3E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS17895 b7335d376eaa30df1a487a13da7d5aaa 256 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 4 254 47.057 T 28-03-2018 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519 WM46_RS24170 45d78f6eaea10e6882016ad9aefdf813 109 Pfam PF05164 Cell division protein ZapA 6 90 3.9E-20 T 28-03-2018 IPR007838 Cell division protein ZapA-like WM46_RS24170 45d78f6eaea10e6882016ad9aefdf813 109 SUPERFAMILY SSF102829 6 94 1.12E-24 T 28-03-2018 IPR007838 Cell division protein ZapA-like WM46_RS24170 45d78f6eaea10e6882016ad9aefdf813 109 Hamap MF_02012 Cell division protein ZapA [zapA]. 1 109 36.753 T 28-03-2018 IPR023771 Cell division protein ZapA, eubacteria WM46_RS04310 ed0f18022e345a1480d01fa29e499af6 261 Pfam PF00950 ABC 3 transport family 1 256 2.7E-88 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 WM46_RS04310 ed0f18022e345a1480d01fa29e499af6 261 SUPERFAMILY SSF81345 3 257 2.09E-41 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS04310 ed0f18022e345a1480d01fa29e499af6 261 Gene3D G3DSA:1.10.3470.10 1 261 3.5E-25 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS02195 f378bf01ff06bbcdfe52d79454073eed 185 SUPERFAMILY SSF52833 46 178 1.2E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS02195 f378bf01ff06bbcdfe52d79454073eed 185 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 178 4.1E-81 T 28-03-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 WM46_RS02195 f378bf01ff06bbcdfe52d79454073eed 185 ProSitePatterns PS00194 Thioredoxin family active site. 72 90 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS02195 f378bf01ff06bbcdfe52d79454073eed 185 Gene3D G3DSA:3.40.30.10 36 185 1.4E-27 T 28-03-2018 WM46_RS02195 f378bf01ff06bbcdfe52d79454073eed 185 Pfam PF08534 Redoxin 42 170 1.6E-22 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 SUPERFAMILY SSF56053 83 177 8.06E-36 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 Pfam PF00347 Ribosomal protein L6 11 82 4.7E-18 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 Pfam PF00347 Ribosomal protein L6 90 164 9.1E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.0E-72 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 PIRSF PIRSF002162 1 177 6.2E-43 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 SUPERFAMILY SSF56053 1 82 2.49E-23 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 7.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 7.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 7.0E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.403 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 Gene3D G3DSA:3.90.930.12 5 85 2.3E-24 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17470 0be5a51a876d81bf46d49f45e62b791b 177 Gene3D G3DSA:3.90.930.12 86 177 5.0E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 Pfam PF00849 RNA pseudouridylate synthase 92 242 7.7E-31 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 Gene3D G3DSA:3.30.2350.10 83 316 4.2E-68 T 28-03-2018 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 SUPERFAMILY SSF55174 17 69 1.85E-11 T 28-03-2018 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 SUPERFAMILY SSF55120 78 322 4.93E-78 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 313 2.4E-108 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 Pfam PF01479 S4 domain 18 65 5.6E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 SMART SM00363 18 83 3.8E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS00270 157c3e5bed9a01d307be709ab3d9cc0e 326 Gene3D G3DSA:3.10.290.10 2 76 2.1E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 Gene3D G3DSA:3.40.47.10 267 417 7.7E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 SUPERFAMILY SSF53901 8 256 8.12E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 250 2.7E-34 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 SMART SM00825 Beta-ketoacyl synthase 10 416 5.6E-7 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 Gene3D G3DSA:3.40.47.10 1 263 4.0E-51 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 SUPERFAMILY SSF53901 219 415 7.12E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS22120 e6fc159385f2e22e88ac3d5f6707c947 417 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 373 1.5E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 SUPERFAMILY SSF142019 10 178 1.7E-45 T 28-03-2018 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 Pfam PF13375 RnfC Barrel sandwich hybrid domain 384 445 2.8E-14 T 28-03-2018 IPR026902 RnfC Barrel sandwich hybrid domain WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 SUPERFAMILY SSF142984 172 240 2.62E-14 T 28-03-2018 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 PIRSF PIRSF036408 12 451 1.7E-194 T 28-03-2018 IPR017054 Propanediol utilization protein, PduS, predicted WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 Pfam PF10531 SLBB domain 175 219 2.3E-12 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 21 160 5.0E-40 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 Pfam PF13534 4Fe-4S dicluster domain 264 324 5.8E-8 T 28-03-2018 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 SUPERFAMILY SSF46548 214 340 6.1E-13 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 Gene3D G3DSA:1.10.1060.10 224 347 7.0E-10 T 28-03-2018 WM46_RS03450 28d31e8b03870686cb385de17c32e198 451 Gene3D G3DSA:2.40.50.100 394 445 0.0023 T 28-03-2018 WM46_RS18870 a5eda1dd99728c845766f11aae0e7127 210 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 14 197 28.679 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 WM46_RS18870 a5eda1dd99728c845766f11aae0e7127 210 Gene3D G3DSA:3.40.50.300 5 207 2.0E-28 T 28-03-2018 WM46_RS18870 a5eda1dd99728c845766f11aae0e7127 210 SUPERFAMILY SSF52540 17 199 8.93E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18870 a5eda1dd99728c845766f11aae0e7127 210 Pfam PF01926 50S ribosome-binding GTPase 28 146 4.1E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS18870 a5eda1dd99728c845766f11aae0e7127 210 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 10 193 5.8E-76 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 WM46_RS22965 28c1adb4e3b81a109a3a49a7f9bf3894 109 Pfam PF07338 Protein of unknown function (DUF1471) 53 108 1.0E-15 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS22965 28c1adb4e3b81a109a3a49a7f9bf3894 109 Gene3D G3DSA:3.30.1660.10 42 108 4.0E-17 T 28-03-2018 IPR025543 Dodecin-like WM46_RS22965 28c1adb4e3b81a109a3a49a7f9bf3894 109 SUPERFAMILY SSF159871 10 108 3.14E-18 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Gene3D G3DSA:3.40.50.300 415 615 7.9E-21 T 28-03-2018 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Pfam PF00005 ABC transporter 806 860 1.1E-5 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 SUPERFAMILY SSF52540 4 204 1.23E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 SUPERFAMILY SSF52540 430 569 1.23E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 940 23.168 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Gene3D G3DSA:3.30.190.20 134 248 9.1E-43 T 28-03-2018 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Gene3D G3DSA:3.40.50.300 616 939 2.4E-54 T 28-03-2018 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Gene3D G3DSA:1.10.8.280 285 405 9.4E-38 T 28-03-2018 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 SUPERFAMILY SSF52540 613 911 1.5E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 925 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Gene3D G3DSA:3.40.50.300 35 133 1.6E-4 T 28-03-2018 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS21660 cf26e07486c16e00c84ac7ecc50454af 940 Gene3D G3DSA:3.40.50.300 3 34 0.0015 T 28-03-2018 WM46_RS02295 09823de0940bd64e2e7fbc04652e7244 604 Gene3D G3DSA:3.10.105.10 315 560 3.2E-47 T 28-03-2018 WM46_RS02295 09823de0940bd64e2e7fbc04652e7244 604 Gene3D G3DSA:3.40.190.10 204 314 1.5E-18 T 28-03-2018 WM46_RS02295 09823de0940bd64e2e7fbc04652e7244 604 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 503 2.4E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS02295 09823de0940bd64e2e7fbc04652e7244 604 Gene3D G3DSA:3.90.76.10 63 203 1.8E-24 T 28-03-2018 WM46_RS02295 09823de0940bd64e2e7fbc04652e7244 604 PIRSF PIRSF002741 3 592 6.9E-167 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS02295 09823de0940bd64e2e7fbc04652e7244 604 SUPERFAMILY SSF53850 49 590 4.81E-110 T 28-03-2018 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 Pfam PF00696 Amino acid kinase family 4 277 4.3E-48 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 PIRSF PIRSF000726 2 449 1.4E-163 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 2.3E-139 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 Gene3D G3DSA:3.30.70.260 284 361 6.3E-20 T 28-03-2018 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 SUPERFAMILY SSF55021 372 448 1.89E-13 T 28-03-2018 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 449 5.9E-150 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 SUPERFAMILY SSF55021 297 393 1.83E-16 T 28-03-2018 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 Gene3D G3DSA:3.40.1160.10 1 283 1.3E-63 T 28-03-2018 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 Gene3D G3DSA:3.30.70.260 372 449 2.1E-14 T 28-03-2018 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 Pfam PF01842 ACT domain 323 378 2.2E-6 T 28-03-2018 IPR002912 ACT domain WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS21495 63d961b9c5c9eaee146514737bbb159b 449 SUPERFAMILY SSF53633 4 292 5.63E-76 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 366 386 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 Gene3D G3DSA:3.30.420.40 2 248 4.2E-67 T 28-03-2018 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 SUPERFAMILY SSF53067 257 500 3.24E-61 T 28-03-2018 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 Gene3D G3DSA:3.30.420.40 249 503 5.5E-59 T 28-03-2018 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 SUPERFAMILY SSF53067 7 254 8.21E-74 T 28-03-2018 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 453 3.2E-44 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 251 3.2E-60 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS11690 b59aa7b68f6c00b8c0dbd1cd1f0e147f 504 PIRSF PIRSF000538 5 503 8.7E-127 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS24720 f61f5df229bb7a26a2268348481eb5ad 301 Pfam PF03824 High-affinity nickel-transport protein 13 298 3.4E-59 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 WM46_RS01385 fbbdf51c4e9967e0332e13da8db374f4 219 Pfam PF00484 Carbonic anhydrase 34 188 2.6E-48 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS01385 fbbdf51c4e9967e0332e13da8db374f4 219 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS01385 fbbdf51c4e9967e0332e13da8db374f4 219 Gene3D G3DSA:3.40.1050.10 1 213 2.1E-65 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS01385 fbbdf51c4e9967e0332e13da8db374f4 219 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 39 46 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS01385 fbbdf51c4e9967e0332e13da8db374f4 219 SUPERFAMILY SSF53056 2 204 3.66E-64 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS01385 fbbdf51c4e9967e0332e13da8db374f4 219 SMART SM00947 27 193 7.0E-65 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 WM46_RS20595 22251f2d28cac04f7aed325c75ce6893 535 PIRSF PIRSF002741 21 535 6.9E-122 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS20595 22251f2d28cac04f7aed325c75ce6893 535 SUPERFAMILY SSF53850 29 534 3.44E-163 T 28-03-2018 WM46_RS20595 22251f2d28cac04f7aed325c75ce6893 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 453 9.8E-109 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS20595 22251f2d28cac04f7aed325c75ce6893 535 Gene3D G3DSA:3.40.190.10 204 299 9.0E-30 T 28-03-2018 WM46_RS20595 22251f2d28cac04f7aed325c75ce6893 535 Gene3D G3DSA:3.10.105.10 300 506 4.7E-66 T 28-03-2018 WM46_RS20595 22251f2d28cac04f7aed325c75ce6893 535 Gene3D G3DSA:3.90.76.10 38 203 1.4E-39 T 28-03-2018 WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 SMART SM00849 11 165 3.3E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 251 45.145 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 Gene3D G3DSA:3.60.15.10 1 251 7.0E-69 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 Pfam PF00753 Metallo-beta-lactamase superfamily 14 165 5.3E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 251 1.1E-102 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 SUPERFAMILY SSF56281 1 251 2.36E-67 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 166 251 3.7E-20 T 28-03-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM46_RS13755 afa0ea26f62cfcea782f4ad6b1422460 251 PIRSF PIRSF005457 1 251 1.0E-89 T 28-03-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 WM46_RS16285 62a75e97331ec682cdb491bae3bea1e0 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 6 224 29.022 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 WM46_RS16285 62a75e97331ec682cdb491bae3bea1e0 224 Pfam PF01730 UreF 38 181 6.8E-31 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 WM46_RS16285 62a75e97331ec682cdb491bae3bea1e0 224 PIRSF PIRSF009467 3 224 2.0E-64 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 SUPERFAMILY SSF56784 1 271 4.33E-63 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 Gene3D G3DSA:3.40.50.1000 1 272 1.6E-39 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 2.9E-22 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 267 4.4E-69 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 267 4.7E-64 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10640 5b3a8228c3e40ec30658dbfd66b2a581 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 221 243 - T 28-03-2018 WM46_RS01330 b85882545976bbac1b4ed6a0cafed8a5 232 Gene3D G3DSA:3.30.2350.10 16 231 2.6E-55 T 28-03-2018 WM46_RS01330 b85882545976bbac1b4ed6a0cafed8a5 232 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 63 77 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01330 b85882545976bbac1b4ed6a0cafed8a5 232 SUPERFAMILY SSF55120 11 227 1.33E-58 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS01330 b85882545976bbac1b4ed6a0cafed8a5 232 Pfam PF00849 RNA pseudouridylate synthase 25 180 6.1E-27 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS02020 31f3735fd41eff5434e305b53ffbf35e 132 Gene3D G3DSA:2.40.33.40 3 116 1.1E-23 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS02020 31f3735fd41eff5434e305b53ffbf35e 132 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 9 105 2.0E-10 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS02020 31f3735fd41eff5434e305b53ffbf35e 132 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 5 113 1.9E-20 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS02020 31f3735fd41eff5434e305b53ffbf35e 132 SUPERFAMILY SSF141530 4 113 1.83E-20 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS13220 c0a45d1547bc0f8a910dcad0651d6f96 404 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 18 392 1.4E-87 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 WM46_RS13220 c0a45d1547bc0f8a910dcad0651d6f96 404 Gene3D G3DSA:1.20.1250.20 19 205 9.6E-30 T 28-03-2018 WM46_RS13220 c0a45d1547bc0f8a910dcad0651d6f96 404 Gene3D G3DSA:1.20.1250.20 208 404 3.7E-17 T 28-03-2018 WM46_RS13220 c0a45d1547bc0f8a910dcad0651d6f96 404 Pfam PF07690 Major Facilitator Superfamily 27 363 3.6E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS13220 c0a45d1547bc0f8a910dcad0651d6f96 404 SUPERFAMILY SSF103473 17 396 3.66E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07595 a77053afaabe250ebf4de081aa7dcb8e 115 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 101 7.0E-47 T 28-03-2018 IPR004480 Monothiol glutaredoxin-related WM46_RS07595 a77053afaabe250ebf4de081aa7dcb8e 115 Pfam PF00462 Glutaredoxin 17 81 1.1E-18 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM46_RS07595 a77053afaabe250ebf4de081aa7dcb8e 115 SUPERFAMILY SSF52833 2 104 1.22E-35 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS07595 a77053afaabe250ebf4de081aa7dcb8e 115 PIRSF PIRSF005894 1 108 2.4E-52 T 28-03-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 WM46_RS07595 a77053afaabe250ebf4de081aa7dcb8e 115 Gene3D G3DSA:3.40.30.10 3 115 6.2E-31 T 28-03-2018 WM46_RS02590 da1be1585ad13382f1bc0ffe5e036971 243 SUPERFAMILY SSF161098 45 233 1.57E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS02590 da1be1585ad13382f1bc0ffe5e036971 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 238 1.3E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS02590 da1be1585ad13382f1bc0ffe5e036971 243 Gene3D G3DSA:1.10.3720.10 7 243 9.1E-28 T 28-03-2018 WM46_RS16870 f67a4665c339e7a7f4cf72595f4ef576 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 406 5.7E-131 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM46_RS16870 f67a4665c339e7a7f4cf72595f4ef576 419 Gene3D G3DSA:3.65.10.10 21 219 1.8E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM46_RS16870 f67a4665c339e7a7f4cf72595f4ef576 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 8.2E-185 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS16870 f67a4665c339e7a7f4cf72595f4ef576 419 SUPERFAMILY SSF55205 1 417 1.03E-147 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 WM46_RS16870 f67a4665c339e7a7f4cf72595f4ef576 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 44.425 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS16870 f67a4665c339e7a7f4cf72595f4ef576 419 Gene3D G3DSA:3.65.10.10 220 418 2.5E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 Gene3D G3DSA:3.40.190.10 120 210 1.9E-18 T 28-03-2018 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 72 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 72 83 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 SUPERFAMILY SSF53850 125 328 4.71E-32 T 28-03-2018 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 SUPERFAMILY SSF46785 33 144 5.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06395 94e9fd511fada9b89991376a89401822 330 Pfam PF03466 LysR substrate binding domain 124 328 2.3E-33 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS06395 94e9fd511fada9b89991376a89401822 330 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 36 95 8.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 Gene3D G3DSA:3.40.190.10 211 298 2.2E-11 T 28-03-2018 WM46_RS06395 94e9fd511fada9b89991376a89401822 330 Gene3D G3DSA:1.10.10.10 29 116 1.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24160 c2bd38e78601b4753c950f0648febf8e 198 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 11 192 3.6E-44 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase WM46_RS24160 c2bd38e78601b4753c950f0648febf8e 198 Gene3D G3DSA:3.40.50.10420 4 198 1.9E-58 T 28-03-2018 WM46_RS24160 c2bd38e78601b4753c950f0648febf8e 198 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 11 192 3.6E-53 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase WM46_RS24160 c2bd38e78601b4753c950f0648febf8e 198 PIRSF PIRSF006806 8 195 2.5E-34 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase WM46_RS24160 c2bd38e78601b4753c950f0648febf8e 198 SUPERFAMILY SSF100950 10 198 1.67E-56 T 28-03-2018 WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 Gene3D G3DSA:3.10.450.50 136 151 0.18 T 28-03-2018 WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 Gene3D G3DSA:3.10.450.50 3 130 2.0E-42 T 28-03-2018 WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 Pfam PF02810 SEC-C motif 134 151 1.7E-10 T 28-03-2018 IPR004027 SEC-C motif WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 Pfam PF02810 SEC-C motif 3 19 6.0E-5 T 28-03-2018 IPR004027 SEC-C motif WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 SUPERFAMILY SSF103642 132 151 1.11E-7 T 28-03-2018 WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 SUPERFAMILY SSF54427 25 129 1.31E-35 T 28-03-2018 IPR032710 NTF2-like domain WM46_RS05700 bb96c09ba1304c49873fd944bb35a79f 151 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 128 29.064 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 WM46_RS24895 e3e7fbb40573e5921fd346aaa2aac63f 106 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS24895 e3e7fbb40573e5921fd346aaa2aac63f 106 Pfam PF12528 Type II secretion prepilin peptidase dependent protein C 33 104 8.0E-24 T 28-03-2018 IPR022204 Prepilin peptidase dependent protein C WM46_RS24895 e3e7fbb40573e5921fd346aaa2aac63f 106 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 1.1E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS24895 e3e7fbb40573e5921fd346aaa2aac63f 106 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 3.0E-6 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site WM46_RS09230 dc8878a0e7dec5c2627c03e3ba379b57 626 Gene3D G3DSA:3.40.30.10 499 610 4.7E-8 T 28-03-2018 WM46_RS09230 dc8878a0e7dec5c2627c03e3ba379b57 626 Pfam PF11412 Disulphide bond corrector protein DsbC 42 147 3.2E-17 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM46_RS09230 dc8878a0e7dec5c2627c03e3ba379b57 626 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 283 484 1.9E-8 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 WM46_RS09230 dc8878a0e7dec5c2627c03e3ba379b57 626 SUPERFAMILY SSF52833 507 619 2.11E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS09230 dc8878a0e7dec5c2627c03e3ba379b57 626 Gene3D G3DSA:2.60.40.1250 29 156 2.4E-7 T 28-03-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain WM46_RS09230 dc8878a0e7dec5c2627c03e3ba379b57 626 Pfam PF13899 Thioredoxin-like 511 590 2.9E-13 T 28-03-2018 WM46_RS18180 2d61976374b639d745a7e6a85d9a78bf 198 Pfam PF03602 Conserved hypothetical protein 95 12 188 3.5E-62 T 28-03-2018 WM46_RS18180 2d61976374b639d745a7e6a85d9a78bf 198 Gene3D G3DSA:3.40.50.150 1 198 2.7E-33 T 28-03-2018 WM46_RS18180 2d61976374b639d745a7e6a85d9a78bf 198 SUPERFAMILY SSF53335 11 189 7.49E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS18180 2d61976374b639d745a7e6a85d9a78bf 198 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 1 190 3.3E-72 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 WM46_RS18180 2d61976374b639d745a7e6a85d9a78bf 198 PIRSF PIRSF004553 11 191 3.7E-59 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 WM46_RS01660 e8308f8795d90597fc9487ffd2f9698d 215 Gene3D G3DSA:1.20.1050.10 95 195 2.0E-30 T 28-03-2018 WM46_RS01660 e8308f8795d90597fc9487ffd2f9698d 215 Pfam PF00043 Glutathione S-transferase, C-terminal domain 133 197 6.1E-12 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS01660 e8308f8795d90597fc9487ffd2f9698d 215 SUPERFAMILY SSF52833 1 84 1.93E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS01660 e8308f8795d90597fc9487ffd2f9698d 215 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 81 9.8E-13 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS01660 e8308f8795d90597fc9487ffd2f9698d 215 Gene3D G3DSA:3.40.30.10 1 94 3.9E-25 T 28-03-2018 WM46_RS01660 e8308f8795d90597fc9487ffd2f9698d 215 SUPERFAMILY SSF47616 78 203 3.55E-34 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 Pfam PF04452 RNA methyltransferase 19 236 2.2E-73 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 SUPERFAMILY SSF88697 2 69 1.02E-17 T 28-03-2018 IPR015947 PUA-like domain WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 2 242 1.9E-93 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 Gene3D G3DSA:2.40.240.20 1 73 1.3E-22 T 28-03-2018 WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 SUPERFAMILY SSF75217 75 242 3.72E-51 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 PIRSF PIRSF015601 2 242 4.2E-52 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS15055 ae6b7190f1152f41e40183f84e19d828 243 Gene3D G3DSA:3.40.1280.10 74 243 6.6E-56 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 145 153 - T 28-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 12 326 7.7E-190 T 28-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 48 60 - T 28-03-2018 IPR000957 Sulphate/thiosulphate-binding, conserved site WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 SUPERFAMILY SSF53850 21 326 1.02E-93 T 28-03-2018 WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 Gene3D G3DSA:3.40.190.10 20 125 1.7E-25 T 28-03-2018 WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 Pfam PF13531 Bacterial extracellular solute-binding protein 32 280 2.2E-46 T 28-03-2018 WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 Gene3D G3DSA:3.40.190.10 126 246 1.4E-27 T 28-03-2018 WM46_RS18500 96758aa6355eeac0c1bc7700fcbed81f 329 Gene3D G3DSA:3.40.190.10 247 329 4.9E-27 T 28-03-2018 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Pfam PF12705 PD-(D/E)XK nuclease superfamily 950 1144 8.1E-5 T 28-03-2018 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 6 1173 23.203 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 SUPERFAMILY SSF52980 899 1174 1.98E-94 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Pfam PF13361 UvrD-like helicase C-terminal domain 681 808 2.5E-11 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 436 9.2E-65 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Gene3D G3DSA:1.10.3170.10 155 349 1.3E-61 T 28-03-2018 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 8 1172 0.0 T 28-03-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Gene3D G3DSA:3.40.50.300 636 872 1.7E-26 T 28-03-2018 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Gene3D G3DSA:3.40.50.300 444 589 1.5E-18 T 28-03-2018 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 Gene3D G3DSA:3.90.320.10 889 1180 1.5E-85 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 SUPERFAMILY SSF52540 325 825 1.84E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 SUPERFAMILY SSF52540 16 80 1.84E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24910 548ee9d44b88bbfee6e6cb4267fbea76 1181 SUPERFAMILY SSF52540 118 202 1.84E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 Pfam PF00816 H-NS histone family 36 127 3.5E-21 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 Gene3D G3DSA:1.10.287.1050 1 57 1.2E-20 T 28-03-2018 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 SUPERFAMILY SSF81273 91 133 6.28E-12 T 28-03-2018 WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 PIRSF PIRSF002096 1 133 1.1E-53 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 Gene3D G3DSA:4.10.430.10 92 133 5.2E-20 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 SMART SM00528 86 133 5.2E-26 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25685 7d9b1bc123b2c0f33726db6279513c42 133 SUPERFAMILY SSF81273 4 58 4.32E-17 T 28-03-2018 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 PRINTS PR00783 Major intrinsic protein family signature 167 189 7.7E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 PRINTS PR00783 Major intrinsic protein family signature 43 67 7.7E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 PRINTS PR00783 Major intrinsic protein family signature 80 99 7.7E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 PRINTS PR00783 Major intrinsic protein family signature 206 226 7.7E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 PRINTS PR00783 Major intrinsic protein family signature 3 22 7.7E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 PRINTS PR00783 Major intrinsic protein family signature 137 155 7.7E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 SUPERFAMILY SSF81338 2 228 3.14E-69 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 Pfam PF00230 Major intrinsic protein 2 223 1.3E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 Gene3D G3DSA:1.20.1080.10 1 231 2.1E-73 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 223 1.5E-64 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 ProSitePatterns PS00221 MIP family signature. 61 69 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS10050 e6c081e10f9fa52b8e98e2bbd31083aa 231 Hamap MF_01146 Aquaporin Z [aqpZ]. 2 230 36.103 T 28-03-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 WM46_RS11595 f96d420d3a974482606af1085a566a35 312 Gene3D G3DSA:3.40.50.1980 149 312 7.3E-33 T 28-03-2018 WM46_RS11595 f96d420d3a974482606af1085a566a35 312 SUPERFAMILY SSF53807 25 300 1.33E-47 T 28-03-2018 WM46_RS11595 f96d420d3a974482606af1085a566a35 312 Gene3D G3DSA:3.40.50.1980 15 148 2.5E-22 T 28-03-2018 WM46_RS11595 f96d420d3a974482606af1085a566a35 312 Pfam PF01497 Periplasmic binding protein 43 290 1.5E-27 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 Pfam PF00551 Formyl transferase 6 184 8.7E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 SUPERFAMILY SSF53328 5 207 2.09E-67 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 SUPERFAMILY SSF50486 208 309 3.92E-37 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 Gene3D G3DSA:3.10.25.10 210 313 1.0E-34 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 307 37.634 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 Gene3D G3DSA:3.40.50.170 2 209 1.2E-69 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 Pfam PF02911 Formyl transferase, C-terminal domain 207 304 5.6E-32 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS17380 50e820d4272c5cc2bab3fc6e4bcfaddb 315 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 5 310 1.7E-123 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 204 218 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 Gene3D G3DSA:3.30.540.10 1 148 1.1E-41 T 28-03-2018 WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 1 244 1.8E-111 T 28-03-2018 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 Pfam PF00459 Inositol monophosphatase family 2 233 1.7E-50 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 SUPERFAMILY SSF56655 1 243 2.62E-76 T 28-03-2018 WM46_RS23060 2307d42eb019c3177fd4f835a06ddc5e 246 Gene3D G3DSA:3.40.190.80 149 245 4.5E-35 T 28-03-2018 WM46_RS22960 d7d70504d2d218e5115d8f16f5caa3c2 95 Gene3D G3DSA:3.30.1660.10 36 94 5.4E-19 T 28-03-2018 IPR025543 Dodecin-like WM46_RS22960 d7d70504d2d218e5115d8f16f5caa3c2 95 Pfam PF07338 Protein of unknown function (DUF1471) 39 94 7.4E-19 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS22960 d7d70504d2d218e5115d8f16f5caa3c2 95 SUPERFAMILY SSF159871 13 94 4.19E-20 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 PIRSF PIRSF004640 1 363 5.9E-148 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 SUPERFAMILY SSF56014 266 333 1.24E-9 T 28-03-2018 WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 Pfam PF04551 GcpE protein 14 353 2.2E-131 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 SUPERFAMILY SSF51717 15 208 2.82E-10 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 Gene3D G3DSA:3.20.20.120 20 176 3.5E-18 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 350 2.2E-125 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 WM46_RS00705 78f61a65a14bb467e18a82d1d7e40945 372 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 357 34.648 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 WM46_RS19635 a8a802f0d44be64679e9db985d203e64 85 Pfam PF01809 Haemolytic domain 10 75 1.1E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor WM46_RS19635 a8a802f0d44be64679e9db985d203e64 85 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 12 77 6.1E-33 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor WM46_RS19635 a8a802f0d44be64679e9db985d203e64 85 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 8 76 25.359 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor WM46_RS19635 a8a802f0d44be64679e9db985d203e64 85 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 22 68 4.0E-21 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor WM46_RS19635 a8a802f0d44be64679e9db985d203e64 85 SMART SM01234 8 75 2.7E-45 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 Gene3D G3DSA:3.40.50.2300 56 178 1.2E-22 T 28-03-2018 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 Pfam PF13377 Periplasmic binding protein-like domain 171 329 5.8E-32 T 28-03-2018 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 Gene3D G3DSA:3.40.50.2300 179 331 1.8E-40 T 28-03-2018 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 9.3E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 SUPERFAMILY SSF53822 61 326 1.18E-54 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 SUPERFAMILY SSF47413 2 61 2.2E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 Gene3D G3DSA:1.10.260.40 4 55 1.1E-21 T 28-03-2018 WM46_RS13140 dee2e81352a3c32098c7936e53cbb858 360 SMART SM00354 3 73 4.2E-34 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS05765 3ffd669edffef94c0c53724409052518 334 SMART SM00382 49 242 2.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS05765 3ffd669edffef94c0c53724409052518 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 329 5.6E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS05765 3ffd669edffef94c0c53724409052518 334 Gene3D G3DSA:3.40.50.300 8 331 4.4E-80 T 28-03-2018 WM46_RS05765 3ffd669edffef94c0c53724409052518 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 311 9.8E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS05765 3ffd669edffef94c0c53724409052518 334 SUPERFAMILY SSF52540 23 264 2.18E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05765 3ffd669edffef94c0c53724409052518 334 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS05765 3ffd669edffef94c0c53724409052518 334 Pfam PF00005 ABC transporter 41 192 4.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Pfam PF04607 Region found in RelA / SpoT proteins 251 360 3.3E-36 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 63 739 4.4E-187 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 SUPERFAMILY SSF81301 196 410 1.8E-63 T 28-03-2018 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Pfam PF13328 HD domain 43 191 1.5E-39 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 SUPERFAMILY SSF81271 399 465 5.07E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Gene3D G3DSA:3.30.460.10 208 341 1.3E-42 T 28-03-2018 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 SUPERFAMILY SSF109604 25 207 1.57E-45 T 28-03-2018 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Gene3D G3DSA:3.30.70.260 660 741 9.4E-12 T 28-03-2018 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 SUPERFAMILY SSF55021 665 741 2.01E-14 T 28-03-2018 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Gene3D G3DSA:3.10.20.30 400 475 9.6E-25 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 SMART SM00954 251 361 8.4E-66 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Pfam PF02824 TGS domain 406 465 4.5E-21 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 WM46_RS25115 8071d0fe21dcdfe03f0de0d86e85d534 744 Pfam PF13291 ACT domain 664 740 3.2E-18 T 28-03-2018 IPR002912 ACT domain WM46_RS14550 235f3f2757dc48a00d92d17950d5396d 784 Pfam PF03968 OstA-like protein 53 194 8.2E-29 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal WM46_RS14550 235f3f2757dc48a00d92d17950d5396d 784 Pfam PF04453 Organic solvent tolerance protein 309 697 1.4E-110 T 28-03-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 WM46_RS14550 235f3f2757dc48a00d92d17950d5396d 784 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 14 763 21.299 T 28-03-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 WM46_RS14550 235f3f2757dc48a00d92d17950d5396d 784 Gene3D G3DSA:2.60.450.10 44 208 1.1E-16 T 28-03-2018 WM46_RS20430 620a14da9d4069f7e523052734be5085 274 SMART SM00047 127 256 3.2E-36 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 WM46_RS20430 620a14da9d4069f7e523052734be5085 274 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 142 267 3.9E-16 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 WM46_RS20430 620a14da9d4069f7e523052734be5085 274 Gene3D G3DSA:1.10.530.10 72 272 2.3E-24 T 28-03-2018 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 Gene3D G3DSA:2.40.50.140 2 70 2.1E-28 T 28-03-2018 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 PIRSF PIRSF002599 1 70 3.2E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 SMART SM00357 6 70 2.5E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 37 - T 28-03-2018 IPR019844 Cold-shock conserved site WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 PRINTS PR00050 Cold shock protein signature 7 22 5.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 PRINTS PR00050 Cold shock protein signature 28 37 5.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 PRINTS PR00050 Cold shock protein signature 43 61 5.8E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 SUPERFAMILY SSF50249 4 69 3.94E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS20500 40785a8282413070fe126dfd41e458ff 70 Pfam PF00313 'Cold-shock' DNA-binding domain 5 69 8.9E-33 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS03010 e9682291fb6d5c6ae6948c2b2c9f6c8a 258 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 44.874 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 WM46_RS03010 e9682291fb6d5c6ae6948c2b2c9f6c8a 258 SUPERFAMILY SSF51366 1 257 8.63E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS03010 e9682291fb6d5c6ae6948c2b2c9f6c8a 258 Gene3D G3DSA:3.20.20.70 4 252 1.4E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS03010 e9682291fb6d5c6ae6948c2b2c9f6c8a 258 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 7.1E-117 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 WM46_RS03010 e9682291fb6d5c6ae6948c2b2c9f6c8a 258 Pfam PF00977 Histidine biosynthesis protein 5 239 4.6E-78 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 182 371 8.8E-28 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 SUPERFAMILY SSF53335 79 392 1.36E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 Gene3D G3DSA:3.30.750.80 74 180 3.2E-33 T 28-03-2018 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 Gene3D G3DSA:3.40.50.150 182 396 4.7E-38 T 28-03-2018 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 Hamap MF_01857 Ribosomal RNA large subunit methyltransferase I [rlmI]. 1 396 70.165 T 28-03-2018 IPR023542 rRNA large subunit methyltransferase I GO:0008649 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 SMART SM00359 3 88 3.3E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 Gene3D G3DSA:2.30.130.10 4 72 1.1E-26 T 28-03-2018 IPR002478 PUA domain GO:0003723 WM46_RS09595 5699eb5d2c3703ba07ba46f156117045 396 SUPERFAMILY SSF88697 4 72 7.1E-17 T 28-03-2018 IPR015947 PUA-like domain WM46_RS09875 d716d706b011f271193b52853c6baa60 230 Gene3D G3DSA:3.30.240.20 97 166 2.9E-19 T 28-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain WM46_RS09875 d716d706b011f271193b52853c6baa60 230 Pfam PF04239 Protein of unknown function (DUF421) 104 168 1.8E-15 T 28-03-2018 IPR007353 Protein of unknown function DUF421 WM46_RS23245 f2166759047a980e2d613924fffb3947 80 Pfam PF04221 RelB antitoxin 1 70 2.1E-15 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ WM46_RS23245 f2166759047a980e2d613924fffb3947 80 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 80 3.4E-22 T 28-03-2018 IPR007337 RelB antitoxin/Antitoxin DinJ WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 311 5.0E-140 T 28-03-2018 IPR010097 Malate dehydrogenase, type 1 GO:0006099|GO:0030060 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263|Reactome: R-HSA-71403 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 Gene3D G3DSA:3.90.110.10 148 312 1.6E-43 T 28-03-2018 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 310 4.1E-52 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 PIRSF PIRSF000102 1 311 4.7E-59 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 Gene3D G3DSA:3.40.50.720 2 147 1.5E-39 T 28-03-2018 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 7.1E-46 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 Hamap MF_01516 Malate dehydrogenase [mdh]. 1 311 60.545 T 28-03-2018 IPR023958 Malate dehydrogenase, type 1, bacterial GO:0006099|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 SUPERFAMILY SSF51735 1 145 2.2E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17080 e5ac7b1972f43fc049c49f0bbbff81da 312 SUPERFAMILY SSF56327 146 311 2.32E-42 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 WM46_RS04090 e8a706f22bd4536cd23827b59a58c35d 266 SUPERFAMILY SSF56784 18 243 4.43E-40 T 28-03-2018 IPR023214 HAD-like domain WM46_RS04090 e8a706f22bd4536cd23827b59a58c35d 266 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 14 243 1.9E-75 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 WM46_RS04090 e8a706f22bd4536cd23827b59a58c35d 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 213 1.8E-23 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS04090 e8a706f22bd4536cd23827b59a58c35d 266 Pfam PF02358 Trehalose-phosphatase 18 229 1.9E-52 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 WM46_RS04090 e8a706f22bd4536cd23827b59a58c35d 266 Gene3D G3DSA:3.40.50.1000 15 260 4.7E-25 T 28-03-2018 IPR023214 HAD-like domain WM46_RS23790 c22a1bbb2006612aacc924e01ca3d037 427 Pfam PF04286 Protein of unknown function (DUF445) 44 417 2.9E-107 T 28-03-2018 IPR007383 Protein of unknown function DUF445 WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 31 158 5.2E-35 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 Gene3D G3DSA:2.60.40.10 163 246 6.3E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 Gene3D G3DSA:2.60.40.10 32 156 3.2E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 SUPERFAMILY SSF49584 164 240 2.49E-17 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 182 239 4.8E-14 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 SUPERFAMILY SSF49354 30 158 3.92E-33 T 28-03-2018 IPR008962 PapD-like WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 PRINTS PR00969 Pili chaperone signature 82 103 1.6E-32 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 PRINTS PR00969 Pili chaperone signature 110 127 1.6E-32 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 PRINTS PR00969 Pili chaperone signature 140 155 1.6E-32 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 PRINTS PR00969 Pili chaperone signature 177 192 1.6E-32 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22425 4d4dc0f1d5140d8a385ab26a8f5f0f42 246 PRINTS PR00969 Pili chaperone signature 32 41 1.6E-32 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 214 238 - T 28-03-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 Gene3D G3DSA:3.30.310.20 1 99 2.7E-31 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 Pfam PF06029 AlkA N-terminal domain 2 112 4.0E-30 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 Gene3D G3DSA:1.10.1670.10 242 280 5.9E-13 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 SMART SM01009 1 112 1.2E-48 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 Gene3D G3DSA:1.10.340.30 100 241 2.6E-25 T 28-03-2018 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 SUPERFAMILY SSF48150 102 274 1.55E-43 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 118 241 4.0E-8 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 SUPERFAMILY SSF55945 1 97 2.51E-26 T 28-03-2018 WM46_RS02755 d3b7806dcf254e1dce2c31fbca94a209 289 SMART SM00478 122 276 9.8E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM46_RS08625 3a41e371e2994708bab8c3b1409f53cd 124 Pfam PF07233 Protein of unknown function (DUF1425) 33 123 2.6E-27 T 28-03-2018 IPR010824 Protein of unknown function DUF1425 WM46_RS03480 e862c3e227aef9f6c60581088256369e 210 Gene3D G3DSA:2.40.40.20 11 187 0.043 T 28-03-2018 WM46_RS03480 e862c3e227aef9f6c60581088256369e 210 PIRSF PIRSF010130 1 210 4.5E-86 T 28-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 WM46_RS03480 e862c3e227aef9f6c60581088256369e 210 Pfam PF06130 Phosphate propanoyltransferase 23 101 1.8E-26 T 28-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 WM46_RS03480 e862c3e227aef9f6c60581088256369e 210 Pfam PF06130 Phosphate propanoyltransferase 131 196 5.1E-18 T 28-03-2018 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420 WM46_RS17535 173fb2cdaacd3678a7968e3a88b6734e 100 Pfam PF00276 Ribosomal protein L23 9 95 5.9E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 WM46_RS17535 173fb2cdaacd3678a7968e3a88b6734e 100 SUPERFAMILY SSF54189 6 97 2.84E-30 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17535 173fb2cdaacd3678a7968e3a88b6734e 100 ProSitePatterns PS00050 Ribosomal protein L23 signature. 81 96 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17535 173fb2cdaacd3678a7968e3a88b6734e 100 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 22.535 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 WM46_RS17535 173fb2cdaacd3678a7968e3a88b6734e 100 Gene3D G3DSA:3.30.70.330 6 100 2.0E-30 T 28-03-2018 WM46_RS01175 c8bbcc7e7f0c309925dbdd5813844ee6 113 Gene3D G3DSA:3.90.20.10 18 109 6.8E-4 T 28-03-2018 WM46_RS01175 c8bbcc7e7f0c309925dbdd5813844ee6 113 Pfam PF14282 FlxA-like protein 17 105 1.8E-20 T 28-03-2018 IPR025577 FlxA-like protein WM46_RS07435 39cf73de33b430233fa67fcdb5de71fe 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 1.2E-92 T 28-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 WM46_RS07435 39cf73de33b430233fa67fcdb5de71fe 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 26.619 T 28-03-2018 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 WM46_RS07435 39cf73de33b430233fa67fcdb5de71fe 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 190 4.3E-61 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 WM46_RS07435 39cf73de33b430233fa67fcdb5de71fe 193 PIRSF PIRSF006102 1 193 1.0E-60 T 28-03-2018 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 509 826 1.0E-93 T 28-03-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 SUPERFAMILY SSF82689 997 1097 1.31E-26 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 Gene3D G3DSA:3.40.50.300 33 798 2.4E-4 T 28-03-2018 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 Gene3D G3DSA:2.30.30.60 946 996 5.8E-13 T 28-03-2018 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 959 993 - T 28-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 SUPERFAMILY SSF82861 845 928 1.22E-8 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 Pfam PF12795 Mechanosensitive ion channel porin domain 50 289 2.9E-61 T 28-03-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 Gene3D G3DSA:3.30.70.100 997 1091 9.9E-21 T 28-03-2018 WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 SUPERFAMILY SSF50182 930 995 1.05E-16 T 28-03-2018 IPR010920 LSM domain WM46_RS12420 bbffaf331241d700208825c994ea1799 1119 Pfam PF00924 Mechanosensitive ion channel 887 1086 1.3E-61 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM46_RS00120 150be5559baea744307e3871e087419e 728 Pfam PF00664 ABC transporter transmembrane region 172 435 4.1E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS00120 150be5559baea744307e3871e087419e 728 SUPERFAMILY SSF90123 155 466 3.53E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS00120 150be5559baea744307e3871e087419e 728 Gene3D G3DSA:3.40.50.300 480 713 3.1E-54 T 28-03-2018 WM46_RS00120 150be5559baea744307e3871e087419e 728 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 19 711 3.9E-233 T 28-03-2018 IPR017750 ATPase, type I secretion system WM46_RS00120 150be5559baea744307e3871e087419e 728 Gene3D G3DSA:3.90.70.10 19 135 1.4E-6 T 28-03-2018 WM46_RS00120 150be5559baea744307e3871e087419e 728 Pfam PF00005 ABC transporter 505 650 1.7E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS00120 150be5559baea744307e3871e087419e 728 SMART SM00382 510 703 4.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00120 150be5559baea744307e3871e087419e 728 SUPERFAMILY SSF52540 474 700 5.43E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00120 150be5559baea744307e3871e087419e 728 Gene3D G3DSA:1.20.1560.10 140 469 1.8E-37 T 28-03-2018 WM46_RS09910 552243ccff9df02a1911886202e39c7f 287 Gene3D G3DSA:1.20.1630.10 3 285 4.1E-44 T 28-03-2018 WM46_RS09910 552243ccff9df02a1911886202e39c7f 287 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 277 3.1E-111 T 28-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 Gene3D G3DSA:1.10.1040.10 272 483 1.0E-61 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 Hamap MF_00670 Altronate oxidoreductase [uxaB]. 1 483 56.237 T 28-03-2018 IPR023668 Altronate oxidoreductase GO:0009026|GO:0055114 KEGG: 00040+1.1.1.58 WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 SUPERFAMILY SSF48179 273 482 2.07E-52 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 17 172 2.7E-39 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 SUPERFAMILY SSF51735 2 264 9.84E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 204 458 2.6E-79 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 WM46_RS07025 a2a73a3efdbe47058e458f2b4e59040d 483 Gene3D G3DSA:3.40.50.720 1 268 1.0E-61 T 28-03-2018 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 SUPERFAMILY SSF52540 35 221 4.28E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 361 1.8E-32 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Gene3D G3DSA:3.40.50.300 1 166 1.1E-39 T 28-03-2018 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Gene3D G3DSA:1.20.272.10 243 363 2.3E-14 T 28-03-2018 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Gene3D G3DSA:1.10.8.60 167 242 1.2E-19 T 28-03-2018 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 356 4.6E-133 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Pfam PF12168 DNA polymerase III subunits tau domain IV DnaB-binding 416 497 1.1E-20 T 28-03-2018 IPR022001 DNA polymerase III subunit tau, DnaB-binding domain IV KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 499 639 4.5E-59 T 28-03-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 SUPERFAMILY SSF48019 243 366 7.06E-36 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.8E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.8E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 Pfam PF13177 DNA polymerase III, delta subunit 20 178 5.8E-42 T 28-03-2018 WM46_RS12390 b57c4fc703cd1b849ec6c64ac977809d 642 SMART SM00382 37 178 1.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 107 430 1.8E-28 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 18 432 64.959 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 24 424 9.0E-159 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 SUPERFAMILY SSF50249 2 66 2.0E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 414 424 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 SUPERFAMILY SSF53335 75 430 5.48E-90 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 Gene3D G3DSA:2.40.50.140 1 87 4.7E-29 T 28-03-2018 WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 Gene3D G3DSA:3.40.50.150 88 431 4.8E-58 T 28-03-2018 WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 Pfam PF01938 TRAM domain 11 66 1.7E-12 T 28-03-2018 IPR002792 TRAM domain WM46_RS25110 ecd4f6c4856d9603d6d4e6a3e5a80dc3 432 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 363 393 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site WM46_RS15050 511f56673f0140d0e5dadaccbd115073 235 Pfam PF04231 Endonuclease I 57 229 8.4E-46 T 28-03-2018 IPR007346 Endonuclease I GO:0004518 WM46_RS15050 511f56673f0140d0e5dadaccbd115073 235 SUPERFAMILY SSF54060 24 230 8.71E-88 T 28-03-2018 WM46_RS22725 927fd9607c331daf328c9ae00cdf4bbf 416 PIRSF PIRSF006060 1 412 1.9E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS22725 927fd9607c331daf328c9ae00cdf4bbf 416 Pfam PF13520 Amino acid permease 8 405 8.2E-32 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS12690 0e69dc4708f6e9ef2f225b9813c9c19e 454 SUPERFAMILY SSF103473 12 391 5.89E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS12690 0e69dc4708f6e9ef2f225b9813c9c19e 454 Gene3D G3DSA:1.20.1250.20 9 198 2.9E-33 T 28-03-2018 WM46_RS12690 0e69dc4708f6e9ef2f225b9813c9c19e 454 Gene3D G3DSA:1.20.1250.20 203 395 1.3E-15 T 28-03-2018 WM46_RS12690 0e69dc4708f6e9ef2f225b9813c9c19e 454 Pfam PF07690 Major Facilitator Superfamily 20 268 4.5E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS12690 0e69dc4708f6e9ef2f225b9813c9c19e 454 Pfam PF07690 Major Facilitator Superfamily 278 393 8.3E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 Pfam PF11967 Recombination protein O N terminal 4 76 5.8E-23 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 Hamap MF_00201 DNA repair protein RecO [recO]. 1 231 23.483 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 SUPERFAMILY SSF57863 86 202 7.06E-9 T 28-03-2018 WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 SUPERFAMILY SSF50249 4 75 1.61E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 Pfam PF02565 Recombination protein O C terminal 83 226 2.6E-22 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 Gene3D G3DSA:2.40.50.140 1 76 5.5E-26 T 28-03-2018 WM46_RS00415 e0f2815085e603d101800e6540cc4caf 236 TIGRFAM TIGR00613 reco: DNA repair protein RecO 5 230 7.1E-38 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 293 1.3E-115 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 Hamap MF_01377 Probable lipid kinase YegS [yegS]. 6 299 44.727 T 28-03-2018 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 129 3.6E-28 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 TIGRFAM TIGR03702 lip_kinase_YegS: lipid kinase YegS 7 298 3.9E-143 T 28-03-2018 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 SUPERFAMILY SSF111331 8 297 7.19E-70 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 Gene3D G3DSA:3.40.50.10330 6 132 1.2E-26 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 WM46_RS02710 b4e17a58a258a95d1fcc61d3016addac 299 SMART SM00046 6 132 1.6E-32 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 SUPERFAMILY SSF109755 13 229 2.83E-70 T 28-03-2018 WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 Gene3D G3DSA:1.20.58.220 120 238 7.8E-26 T 28-03-2018 WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 Pfam PF01895 PhoU domain 27 111 8.9E-21 T 28-03-2018 IPR026022 PhoU domain WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 Pfam PF01895 PhoU domain 128 213 1.6E-17 T 28-03-2018 IPR026022 PhoU domain WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 Gene3D G3DSA:1.20.58.220 6 119 2.1E-27 T 28-03-2018 WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 13 221 6.2E-72 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 WM46_RS19570 98ceeec4a0e3c452eeaa2c28816d6512 241 PIRSF PIRSF003107 7 226 5.9E-68 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 WM46_RS17610 2ec1494ae28f176c6855b9a9ee43133b 240 Pfam PF13309 HTH domain 171 228 3.3E-19 T 28-03-2018 WM46_RS17610 2ec1494ae28f176c6855b9a9ee43133b 240 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 27 153 1.0E-68 T 28-03-2018 IPR013559 YheO-like WM46_RS17610 2ec1494ae28f176c6855b9a9ee43133b 240 Pfam PF08348 YheO-like PAS domain 29 137 3.6E-36 T 28-03-2018 IPR013559 YheO-like WM46_RS17610 2ec1494ae28f176c6855b9a9ee43133b 240 Gene3D G3DSA:1.10.10.60 185 240 3.4E-6 T 28-03-2018 WM46_RS24460 200cf3a561e2ce8c338ac9ef7136fe7b 139 Pfam PF05025 RbsD / FucU transport protein family 1 133 3.6E-27 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS24460 200cf3a561e2ce8c338ac9ef7136fe7b 139 SUPERFAMILY SSF102546 1 133 1.31E-23 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS24460 200cf3a561e2ce8c338ac9ef7136fe7b 139 Gene3D G3DSA:3.40.1650.10 1 136 9.3E-25 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS01245 59ec9467beba09f75c29946225640337 120 Gene3D G3DSA:1.10.10.10 3 65 1.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01245 59ec9467beba09f75c29946225640337 120 SUPERFAMILY SSF46955 3 54 2.11E-13 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS01245 59ec9467beba09f75c29946225640337 120 Pfam PF07037 Putative transcription regulator (DUF1323) 6 119 5.6E-50 T 28-03-2018 IPR010749 Protein of unknown function DUF1323 WM46_RS01245 59ec9467beba09f75c29946225640337 120 ProDom PD060594 TRANSCRIPTION YFED YFEC DNA-BINDING REGULATION NEGATIVE REGULATOR STY2653 ECS3274 STY2652 6 120 4.0E-52 T 28-03-2018 IPR010749 Protein of unknown function DUF1323 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Pfam PF00128 Alpha amylase, catalytic domain 273 347 7.4E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 109 723 0.0 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 PIRSF PIRSF000463 6 728 2.4E-287 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 SUPERFAMILY SSF81296 117 223 8.4E-36 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 SUPERFAMILY SSF81296 16 115 1.54E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 SUPERFAMILY SSF51445 230 621 5.02E-111 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Gene3D G3DSA:3.20.20.80 242 634 7.5E-71 T 28-03-2018 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 SUPERFAMILY SSF51011 624 726 5.65E-36 T 28-03-2018 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Gene3D G3DSA:2.60.40.10 112 223 2.4E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Gene3D G3DSA:2.60.40.10 1 104 8.2E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 101 726 43.782 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 SMART SM00642 247 596 3.3E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 125 207 7.1E-26 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Gene3D G3DSA:2.60.40.1180 635 726 6.9E-35 T 28-03-2018 WM46_RS18030 0eb4998bc994d8181508d12403209a5e 728 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 628 725 6.8E-25 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 Gene3D G3DSA:3.30.1490.20 115 170 2.1E-12 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 SUPERFAMILY SSF56059 98 288 6.36E-51 T 28-03-2018 WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 286 3.7E-95 T 28-03-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 Gene3D G3DSA:3.40.50.20 1 114 1.7E-32 T 28-03-2018 WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 54.481 T 28-03-2018 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 Pfam PF08443 RimK-like ATP-grasp domain 97 286 3.9E-80 T 28-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 WM46_RS10170 68d6f95802267495d7ec6ffeee69aaaf 300 Gene3D G3DSA:3.30.470.20 171 277 1.2E-35 T 28-03-2018 WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 SMART SM00895 84 210 3.0E-6 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 Pfam PF07729 FCD domain 84 208 1.1E-15 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 Gene3D G3DSA:1.20.120.530 71 220 1.2E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 5.4E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 SMART SM00345 16 74 3.3E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 SUPERFAMILY SSF48008 82 212 9.68E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 Gene3D G3DSA:1.10.10.10 1 70 1.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06640 22b70075ea898a490fed51877ad5d901 221 SUPERFAMILY SSF46785 5 78 2.93E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04355 b229a7783b4461930792e6b136f2d211 213 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 40 49 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS04355 b229a7783b4461930792e6b136f2d211 213 Gene3D G3DSA:3.20.20.70 1 213 4.6E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS04355 b229a7783b4461930792e6b136f2d211 213 SUPERFAMILY SSF51569 4 209 6.78E-69 T 28-03-2018 WM46_RS04355 b229a7783b4461930792e6b136f2d211 213 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS04355 b229a7783b4461930792e6b136f2d211 213 Pfam PF01081 KDPG and KHG aldolase 9 203 7.4E-92 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS04355 b229a7783b4461930792e6b136f2d211 213 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 209 1.7E-86 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS08315 b4491d1c837ecaccee36bd63109c260a 417 Pfam PF00704 Glycosyl hydrolases family 18 26 400 2.1E-66 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 WM46_RS08315 b4491d1c837ecaccee36bd63109c260a 417 ProSitePatterns PS01095 Chitinases family 18 active site. 145 153 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 WM46_RS08315 b4491d1c837ecaccee36bd63109c260a 417 SMART SM00636 23 400 4.7E-71 T 28-03-2018 IPR011583 Chitinase II GO:0008061 WM46_RS08315 b4491d1c837ecaccee36bd63109c260a 417 SUPERFAMILY SSF51445 15 276 5.13E-73 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS08315 b4491d1c837ecaccee36bd63109c260a 417 SUPERFAMILY SSF51445 372 404 5.13E-73 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS08315 b4491d1c837ecaccee36bd63109c260a 417 Gene3D G3DSA:3.20.20.80 14 416 3.4E-79 T 28-03-2018 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 2.9E-51 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 Gene3D G3DSA:3.30.70.260 328 409 1.0E-16 T 28-03-2018 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 SUPERFAMILY SSF52283 7 138 3.83E-50 T 28-03-2018 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 SUPERFAMILY SSF51735 108 295 3.76E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 SUPERFAMILY SSF55021 328 409 1.03E-19 T 28-03-2018 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 Gene3D G3DSA:3.40.50.720 136 295 7.4E-42 T 28-03-2018 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 326 1.1E-37 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site WM46_RS24155 6633c8cd5badee9ce5c639f06b6ffc4a 410 Gene3D G3DSA:3.40.50.720 1 135 1.9E-42 T 28-03-2018 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 Pfam PF12833 Helix-turn-helix domain 213 289 4.3E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 Pfam PF07883 Cupin domain 38 99 2.1E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 285 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 4.7E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 4.7E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 Gene3D G3DSA:2.60.120.280 14 177 1.7E-16 T 28-03-2018 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 Gene3D G3DSA:1.10.10.60 245 292 2.7E-13 T 28-03-2018 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 SUPERFAMILY SSF51182 41 123 1.07E-9 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 Gene3D G3DSA:1.10.10.60 188 244 2.7E-8 T 28-03-2018 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 SUPERFAMILY SSF46689 244 290 2.51E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 TIGRFAM TIGR02297 HpaA: 4-hydroxyphenylacetate catabolism regulatory protein HpaA 6 290 9.5E-119 T 28-03-2018 IPR011983 4-hydroxyphenylacetate catabolism regulatory protein HpaA WM46_RS13375 fae4048caf5bcbd1d6b507aeb56b11af 296 SMART SM00342 206 289 4.8E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 SUPERFAMILY SSF53901 5 269 1.75E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 5.5E-52 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 PIRSF PIRSF000429 1 392 9.6E-126 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 Gene3D G3DSA:3.40.47.10 265 389 3.4E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 Gene3D G3DSA:3.40.47.10 152 264 2.4E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 SUPERFAMILY SSF53901 270 391 7.34E-46 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 1.3E-94 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 Gene3D G3DSA:3.40.47.10 1 148 2.3E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS17960 fde6d65d21cb8b6528b0e07fa7c50c0f 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 390 1.3E-140 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 Gene3D G3DSA:3.40.50.150 2 250 1.2E-47 T 28-03-2018 WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 158 172 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 SUPERFAMILY SSF53335 18 249 2.32E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 16 250 39.269 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 Pfam PF01209 ubiE/COQ5 methyltransferase family 16 250 6.7E-113 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 36 51 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 WM46_RS19015 9ca24983915c312e0424934befe0c3ee 251 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 25 250 5.5E-89 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 WM46_RS15495 1ed7055202447e8436f409ba131b0221 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 2.5E-54 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS15495 1ed7055202447e8436f409ba131b0221 272 Gene3D G3DSA:3.40.50.1000 1 269 1.8E-31 T 28-03-2018 IPR023214 HAD-like domain WM46_RS15495 1ed7055202447e8436f409ba131b0221 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 2.4E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS15495 1ed7055202447e8436f409ba131b0221 272 SUPERFAMILY SSF56784 1 264 6.5E-59 T 28-03-2018 IPR023214 HAD-like domain WM46_RS15495 1ed7055202447e8436f409ba131b0221 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 213 235 - T 28-03-2018 WM46_RS15495 1ed7055202447e8436f409ba131b0221 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 4.8E-51 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03635 144ca7d2f884000214172ab3d785f113 247 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 247 49.507 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03635 144ca7d2f884000214172ab3d785f113 247 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 246 1.2E-83 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03635 144ca7d2f884000214172ab3d785f113 247 Pfam PF02654 Cobalamin-5-phosphate synthase 9 244 1.0E-53 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS13395 a57646e18e00c032a97bf088818e86c9 100 Gene3D G3DSA:3.90.1240.10 54 100 2.9E-8 T 28-03-2018 WM46_RS13395 a57646e18e00c032a97bf088818e86c9 100 SUPERFAMILY SSF46689 63 98 3.72E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13395 a57646e18e00c032a97bf088818e86c9 100 Gene3D G3DSA:1.10.10.60 21 53 0.54 T 28-03-2018 WM46_RS13395 a57646e18e00c032a97bf088818e86c9 100 Pfam PF12833 Helix-turn-helix domain 42 98 4.3E-10 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 286 30.65 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 Hamap MF_01578 Quinate/shikimate dehydrogenase [ydiB]. 1 288 77.452 T 28-03-2018 IPR022872 Quinate/Shikimate dehydrogenase GO:0004764|GO:0030266|GO:0052733|GO:0052734|GO:0055114 KEGG: 00400+1.1.1.282|KEGG: 00620+1.1.1.28|MetaCyc: PWY-6163|MetaCyc: PWY-6454|MetaCyc: PWY-6901 WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 SUPERFAMILY SSF53223 4 106 4.03E-29 T 28-03-2018 WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 Gene3D G3DSA:3.40.50.10860 1 116 1.2E-36 T 28-03-2018 WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 SUPERFAMILY SSF51735 107 284 3.1E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 Gene3D G3DSA:3.40.50.720 117 287 6.1E-33 T 28-03-2018 WM46_RS07905 a9e4ec8e85ed687579c5ab0abb5cbeda 288 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 7.4E-26 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM46_RS11340 63d21ae53bcd7225cf6e374678a14d83 311 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 28-03-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 WM46_RS11340 63d21ae53bcd7225cf6e374678a14d83 311 Hamap MF_01431 Pyrimidine-specific ribonucleoside hydrolase RihA [rihA]. 1 311 80.132 T 28-03-2018 IPR022975 Pyrimidine-specific ribonucleoside hydrolase RihA GO:0005737|GO:0006206|GO:0008152|GO:0015949|GO:0016787|GO:0016798|GO:0045437 WM46_RS11340 63d21ae53bcd7225cf6e374678a14d83 311 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 300 2.2E-92 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain WM46_RS11340 63d21ae53bcd7225cf6e374678a14d83 311 Gene3D G3DSA:3.90.245.10 2 311 2.9E-117 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain WM46_RS11340 63d21ae53bcd7225cf6e374678a14d83 311 SUPERFAMILY SSF53590 4 308 3.92E-108 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 SUPERFAMILY SSF52540 8 220 9.54E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 Gene3D G3DSA:2.40.50.100 273 349 5.6E-21 T 28-03-2018 WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 Pfam PF03459 TOBE domain 290 350 1.2E-16 T 28-03-2018 IPR005116 Transport-associated OB, type 1 WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 SUPERFAMILY SSF50331 235 350 1.65E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 Gene3D G3DSA:3.40.50.300 15 262 3.8E-55 T 28-03-2018 WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 288 351 6.7E-23 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 Pfam PF00005 ABC transporter 18 156 7.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 SMART SM00382 23 206 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 2 350 1.4E-162 T 28-03-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 WM46_RS10645 30c6a865816e6b2055d7d750e3f140bc 352 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS00820 f624bef7368aa07c8d3b8506430777a2 119 Gene3D G3DSA:3.40.30.10 1 119 4.1E-37 T 28-03-2018 WM46_RS00820 f624bef7368aa07c8d3b8506430777a2 119 SUPERFAMILY SSF52833 5 118 7.59E-36 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS00820 f624bef7368aa07c8d3b8506430777a2 119 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 5 118 2.1E-48 T 28-03-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 WM46_RS00820 f624bef7368aa07c8d3b8506430777a2 119 Pfam PF03960 ArsC family 8 117 4.8E-22 T 28-03-2018 IPR006660 Arsenate reductase-like WM46_RS16885 b0792fe4fd1389acc35c443c028297d1 211 Gene3D G3DSA:3.10.450.50 72 172 9.9E-22 T 28-03-2018 WM46_RS16885 b0792fe4fd1389acc35c443c028297d1 211 Gene3D G3DSA:3.10.450.50 26 71 6.0E-5 T 28-03-2018 WM46_RS16885 b0792fe4fd1389acc35c443c028297d1 211 PIRSF PIRSF004649 1 211 1.1E-62 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC WM46_RS16885 b0792fe4fd1389acc35c443c028297d1 211 Pfam PF05494 MlaC protein 33 198 1.3E-53 T 28-03-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Pfam PF00570 HRDC domain 533 599 2.9E-24 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SUPERFAMILY SSF47819 530 605 3.49E-26 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SMART SM00490 250 331 1.8E-28 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Pfam PF00271 Helicase conserved C-terminal domain 222 330 6.5E-21 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Gene3D G3DSA:3.40.50.300 1 208 2.5E-37 T 28-03-2018 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Pfam PF16124 RecQ zinc-binding 343 404 1.2E-15 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Gene3D G3DSA:1.10.150.80 524 609 5.5E-27 T 28-03-2018 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 15 464 8.6E-206 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SUPERFAMILY SSF52540 7 200 1.95E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SUPERFAMILY SSF52540 208 455 7.73E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SMART SM00487 22 216 1.9E-28 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SMART SM00341 529 609 1.5E-31 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Gene3D G3DSA:1.10.10.10 404 523 1.7E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 SMART SM00956 411 514 2.5E-45 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Pfam PF09382 RQC domain 406 514 6.5E-33 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Pfam PF00270 DEAD/DEAH box helicase 28 186 6.3E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 13 601 6.1E-275 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 WM46_RS19070 f2ebf0ebda4bebe606565f85cdb29361 609 Gene3D G3DSA:3.40.50.300 210 403 2.6E-49 T 28-03-2018 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 SUPERFAMILY SSF53182 1 214 9.16E-74 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 200 41.193 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 Pfam PF01470 Pyroglutamyl peptidase 3 201 7.7E-82 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 2.3E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 161 173 2.3E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 2.3E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 2.3E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 2.3E-48 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 Gene3D G3DSA:3.40.630.20 1 214 7.5E-66 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 PIRSF PIRSF015592 1 212 2.8E-85 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 WM46_RS11035 54ab7eb84c86815793d913a00b2b64a9 214 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 211 1.4E-89 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 WM46_RS25260 e81f4aa9e347643209fc863774f291ab 233 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 7 227 44.521 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 WM46_RS25260 e81f4aa9e347643209fc863774f291ab 233 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 102 109 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 WM46_RS25260 e81f4aa9e347643209fc863774f291ab 233 Gene3D G3DSA:3.90.550.10 2 233 1.6E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS25260 e81f4aa9e347643209fc863774f291ab 233 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 8 229 8.9E-93 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 WM46_RS25260 e81f4aa9e347643209fc863774f291ab 233 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 9 227 5.6E-79 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 WM46_RS25260 e81f4aa9e347643209fc863774f291ab 233 SUPERFAMILY SSF53448 8 227 6.72E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS12580 26b69faae9d632f325c7d1c1986aa470 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 3.2E-43 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS12580 26b69faae9d632f325c7d1c1986aa470 351 Gene3D G3DSA:3.40.50.1100 142 330 2.0E-39 T 28-03-2018 WM46_RS12580 26b69faae9d632f325c7d1c1986aa470 351 SUPERFAMILY SSF53686 7 333 4.71E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS12580 26b69faae9d632f325c7d1c1986aa470 351 Gene3D G3DSA:3.40.50.1100 31 141 3.2E-22 T 28-03-2018 WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 Gene3D G3DSA:2.60.40.10 27 147 2.1E-32 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 28 149 3.4E-37 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 Gene3D G3DSA:2.60.40.10 153 242 2.9E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 176 238 8.3E-11 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 SUPERFAMILY SSF49354 21 148 1.31E-34 T 28-03-2018 IPR008962 PapD-like WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 SUPERFAMILY SSF49584 153 241 1.15E-11 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 PRINTS PR00969 Pili chaperone signature 171 186 8.6E-27 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 PRINTS PR00969 Pili chaperone signature 26 35 8.6E-27 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 PRINTS PR00969 Pili chaperone signature 105 122 8.6E-27 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 PRINTS PR00969 Pili chaperone signature 75 96 8.6E-27 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19990 91eb583029d0d37a2a91087a3ddb281b 243 PRINTS PR00969 Pili chaperone signature 131 146 8.6E-27 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 342 88.949 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 Gene3D G3DSA:3.30.465.10 69 218 5.1E-48 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 SUPERFAMILY SSF56176 3 197 3.88E-47 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 SUPERFAMILY SSF56194 202 340 1.83E-51 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 Pfam PF01565 FAD binding domain 20 148 6.1E-24 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 5 330 4.5E-118 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 Gene3D G3DSA:3.30.43.10 3 68 3.5E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 206 329 3.5E-32 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21115 b284a2becd3b150b45cfe7f10bac71eb 342 Gene3D G3DSA:3.90.78.10 221 334 3.1E-40 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS25925 81b38af318a7ce2b2f8a595ae26f4172 402 Pfam PF09019 EcoRII C terminal 227 391 2.4E-72 T 28-03-2018 IPR015109 Restriction endonuclease, type II, EcoRII, C-terminal GO:0003677|GO:0009036|GO:0009307 WM46_RS25925 81b38af318a7ce2b2f8a595ae26f4172 402 Gene3D G3DSA:2.40.330.10 1 175 6.5E-38 T 28-03-2018 IPR015300 DNA-binding pseudobarrel domain WM46_RS25925 81b38af318a7ce2b2f8a595ae26f4172 402 Pfam PF09217 Restriction endonuclease EcoRII, N-terminal 14 163 4.6E-65 T 28-03-2018 IPR023372 Restriction endonuclease, type II, EcoRII, N-terminal WM46_RS25925 81b38af318a7ce2b2f8a595ae26f4172 402 SUPERFAMILY SSF101936 3 174 1.33E-61 T 28-03-2018 IPR015300 DNA-binding pseudobarrel domain WM46_RS25925 81b38af318a7ce2b2f8a595ae26f4172 402 SUPERFAMILY SSF52980 178 395 3.65E-83 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS21460 86c116fd3e882be8d27020dfc9c3fc3b 528 Gene3D G3DSA:3.40.50.2300 1 224 1.2E-5 T 28-03-2018 WM46_RS13350 49be2a6540a902ee9fa72ed7c741173b 285 SUPERFAMILY SSF53213 12 279 2.62E-49 T 28-03-2018 WM46_RS13350 49be2a6540a902ee9fa72ed7c741173b 285 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 279 5.1E-81 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 WM46_RS13350 49be2a6540a902ee9fa72ed7c741173b 285 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 281 1.0E-160 T 28-03-2018 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase GO:0008687 KEGG: 00350+1.13.11.15 WM46_RS13350 49be2a6540a902ee9fa72ed7c741173b 285 Gene3D G3DSA:3.40.830.10 2 276 1.2E-51 T 28-03-2018 WM46_RS11845 a9ef9a6cc0bbf49a5bc9fe2c3ce4e6d4 420 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 319 3.0E-59 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS11845 a9ef9a6cc0bbf49a5bc9fe2c3ce4e6d4 420 SUPERFAMILY SSF111369 123 324 6.28E-12 T 28-03-2018 WM46_RS11845 a9ef9a6cc0bbf49a5bc9fe2c3ce4e6d4 420 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 203 397 2.4E-33 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS11845 a9ef9a6cc0bbf49a5bc9fe2c3ce4e6d4 420 Gene3D G3DSA:2.40.50.100 127 245 6.6E-10 T 28-03-2018 WM46_RS10750 f934de9a36fda03a3d96726b7bfe2514 124 ProDom PD079292 YBGS HOMEOBOX PRECURSOR SIGNAL PROBABLE SECRETED 50 124 3.0E-29 T 28-03-2018 IPR020363 Uncharacterised protein family YbgS WM46_RS10750 f934de9a36fda03a3d96726b7bfe2514 124 Pfam PF13985 YbgS-like protein 3 124 3.7E-52 T 28-03-2018 IPR020363 Uncharacterised protein family YbgS WM46_RS08345 7a71be9345e8928f5aa54e5e9ad48ee3 294 PIRSF PIRSF016020 11 294 2.0E-52 T 28-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 WM46_RS08345 7a71be9345e8928f5aa54e5e9ad48ee3 294 Gene3D G3DSA:2.70.98.10 1 294 4.2E-64 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS08345 7a71be9345e8928f5aa54e5e9ad48ee3 294 Pfam PF01263 Aldose 1-epimerase 27 274 4.8E-44 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 WM46_RS08345 7a71be9345e8928f5aa54e5e9ad48ee3 294 SUPERFAMILY SSF74650 8 270 2.89E-65 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS07640 b1e91eb0937186f05562541897d91989 382 PIRSF PIRSF003085 2 381 1.4E-129 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 WM46_RS07640 b1e91eb0937186f05562541897d91989 382 Gene3D G3DSA:3.40.50.150 105 372 3.9E-65 T 28-03-2018 WM46_RS07640 b1e91eb0937186f05562541897d91989 382 Pfam PF02353 Mycolic acid cyclopropane synthetase 108 368 3.9E-104 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS07640 b1e91eb0937186f05562541897d91989 382 SUPERFAMILY SSF53335 117 373 1.88E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS14345 682079fef5d34b7897baa1aef0341192 168 Hamap MF_01332 Secretion monitor [secM]. 1 168 41.158 T 28-03-2018 IPR009502 Secretion monitor GO:0045182 WM46_RS14345 682079fef5d34b7897baa1aef0341192 168 Pfam PF06558 Secretion monitor precursor protein (SecM) 24 165 9.2E-55 T 28-03-2018 IPR009502 Secretion monitor GO:0045182 WM46_RS14345 682079fef5d34b7897baa1aef0341192 168 PIRSF PIRSF004572 1 168 6.1E-82 T 28-03-2018 IPR009502 Secretion monitor GO:0045182 WM46_RS14345 682079fef5d34b7897baa1aef0341192 168 ProDom PD089227 MONITOR PERIPLASMIC SECRETION PRECURSOR SIGNAL YACA 1 168 4.0E-67 T 28-03-2018 IPR009502 Secretion monitor GO:0045182 WM46_RS14990 6f327595d5b17adde59579fc9d019703 459 Gene3D G3DSA:3.40.50.2300 358 459 4.2E-17 T 28-03-2018 WM46_RS14990 6f327595d5b17adde59579fc9d019703 459 SUPERFAMILY SSF52794 369 455 1.52E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS14990 6f327595d5b17adde59579fc9d019703 459 Pfam PF02378 Phosphotransferase system, EIIC 20 277 7.5E-20 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS14990 6f327595d5b17adde59579fc9d019703 459 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 372 446 5.1E-11 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS14990 6f327595d5b17adde59579fc9d019703 459 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 9 344 2.7E-144 T 28-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS01300 00af0dfac36a007696935f7c23f7241a 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 270 282 1.5E-5 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 WM46_RS01300 00af0dfac36a007696935f7c23f7241a 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 283 296 1.5E-5 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 WM46_RS01300 00af0dfac36a007696935f7c23f7241a 332 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 126 136 1.5E-5 T 28-03-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 WM46_RS01300 00af0dfac36a007696935f7c23f7241a 332 Gene3D G3DSA:3.20.20.100 15 332 6.7E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS01300 00af0dfac36a007696935f7c23f7241a 332 SUPERFAMILY SSF51430 13 329 2.23E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS01300 00af0dfac36a007696935f7c23f7241a 332 Pfam PF00248 Aldo/keto reductase family 28 328 1.9E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 SUPERFAMILY SSF55979 245 366 1.47E-37 T 28-03-2018 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 120 3.4E-40 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 SMART SM00480 17 362 1.8E-173 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 Gene3D G3DSA:3.10.150.10 248 366 3.9E-25 T 28-03-2018 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 243 6.3E-41 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 5.0E-114 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 SUPERFAMILY SSF55979 1 121 1.0E-25 T 28-03-2018 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 245 365 4.6E-45 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 Gene3D G3DSA:3.10.150.10 1 123 1.1E-27 T 28-03-2018 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 Gene3D G3DSA:3.10.150.10 124 247 2.3E-33 T 28-03-2018 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 PIRSF PIRSF000804 1 366 5.5E-117 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS19655 3c82cb8d6f0db855512cf3578b007cd3 366 SUPERFAMILY SSF55979 125 244 4.45E-30 T 28-03-2018 WM46_RS09900 fa780cd1f1250c583cac991004fd2935 382 Pfam PF07690 Major Facilitator Superfamily 12 228 6.1E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS09900 fa780cd1f1250c583cac991004fd2935 382 Gene3D G3DSA:1.20.1250.20 4 186 8.1E-22 T 28-03-2018 WM46_RS09900 fa780cd1f1250c583cac991004fd2935 382 Hamap MF_01149 Uncharacterized MFS-type transporter YcaD [ycaD]. 1 382 36.28 T 28-03-2018 IPR023745 MSF-type transporter, YcaD WM46_RS09900 fa780cd1f1250c583cac991004fd2935 382 Gene3D G3DSA:1.20.1250.20 187 379 2.0E-19 T 28-03-2018 WM46_RS09900 fa780cd1f1250c583cac991004fd2935 382 SUPERFAMILY SSF103473 6 375 2.49E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 Pfam PF04715 Anthranilate synthase component I, N terminal region 20 190 4.1E-12 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 PIRSF PIRSF001373 1 520 1.4E-248 T 28-03-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 Pfam PF00425 chorismate binding enzyme 242 502 7.8E-84 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 PRINTS PR00095 Anthranilate synthase component I signature 350 363 6.9E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 PRINTS PR00095 Anthranilate synthase component I signature 444 458 6.9E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 PRINTS PR00095 Anthranilate synthase component I signature 364 377 6.9E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 PRINTS PR00095 Anthranilate synthase component I signature 459 473 6.9E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 17 515 1.1E-266 T 28-03-2018 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 SUPERFAMILY SSF56322 7 516 2.35E-164 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS05850 9ac0f19be49b65aea1c14ed18835c9b4 520 Gene3D G3DSA:3.60.120.10 1 520 5.2E-160 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS09345 78cf191d063e10af9d7d12b25b3e2baf 86 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site WM46_RS09345 78cf191d063e10af9d7d12b25b3e2baf 86 SUPERFAMILY SSF47336 24 79 3.8E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS09345 78cf191d063e10af9d7d12b25b3e2baf 86 Pfam PF00550 Phosphopantetheine attachment site 23 74 2.7E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS09345 78cf191d063e10af9d7d12b25b3e2baf 86 Gene3D G3DSA:1.10.1200.10 4 76 1.4E-13 T 28-03-2018 WM46_RS02810 af38733d36f94a85326c47a7c03e444c 280 Gene3D G3DSA:3.90.550.10 2 268 1.2E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02810 af38733d36f94a85326c47a7c03e444c 280 SUPERFAMILY SSF53448 6 234 7.22E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02810 af38733d36f94a85326c47a7c03e444c 280 Pfam PF00535 Glycosyl transferase family 2 9 138 2.8E-26 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS02810 af38733d36f94a85326c47a7c03e444c 280 TIGRFAM TIGR04017 WcaA: colanic acid biosynthesis glycosyltransferase WcaA 3 280 5.6E-194 T 28-03-2018 IPR024009 Colanic acid biosynthesis, glycosyl transferase, WcaA WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 SUPERFAMILY SSF52172 3 162 3.52E-34 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 5.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 SMART SM00448 2 115 2.6E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 7.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 7.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 7.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 SMART SM00421 147 204 2.4E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 Gene3D G3DSA:1.10.10.10 126 214 3.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 SUPERFAMILY SSF46894 147 210 2.55E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 Pfam PF00072 Response regulator receiver domain 4 115 8.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03930 8f6fc1d2a744920753608eef88acb827 218 Gene3D G3DSA:3.40.50.2300 1 125 2.4E-35 T 28-03-2018 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 PIRSF PIRSF000460 1 815 6.3E-235 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 654 666 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 SUPERFAMILY SSF53756 8 814 0.0 T 28-03-2018 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 Gene3D G3DSA:3.40.50.2000 480 795 1.0E-144 T 28-03-2018 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 14 810 0.0 T 28-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 Gene3D G3DSA:3.40.50.2000 6 479 4.0E-197 T 28-03-2018 WM46_RS18010 b07067e9b976db7eecdf87f4d8c3bcaa 815 Pfam PF00343 Carbohydrate phosphorylase 102 810 0.0 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 4 437 2.0E-218 T 28-03-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 Hamap MF_00455 Xylose isomerase [xylA]. 11 437 53.543 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 133 153 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 180 201 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 229 253 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 156 175 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 207 226 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 300 311 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 271 298 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 92 114 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 PRINTS PR00688 Xylose isomerase signature 333 344 1.3E-84 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 Gene3D G3DSA:3.20.20.150 2 440 7.6E-110 T 28-03-2018 WM46_RS20455 8cdb3ef8cb43a7f2a3245118b85c4e73 440 SUPERFAMILY SSF51658 4 438 1.02E-172 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS17465 dbe782da2b9c8072406e13de5b866cf0 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 26.257 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17465 dbe782da2b9c8072406e13de5b866cf0 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 7.1E-44 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17465 dbe782da2b9c8072406e13de5b866cf0 117 SUPERFAMILY SSF53137 3 115 7.85E-54 T 28-03-2018 WM46_RS17465 dbe782da2b9c8072406e13de5b866cf0 117 Gene3D G3DSA:3.30.420.100 1 117 4.2E-39 T 28-03-2018 WM46_RS17465 dbe782da2b9c8072406e13de5b866cf0 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 4.0E-47 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS04195 6bce4ea9e14c3f54ac38b99eb42ced6f 378 SUPERFAMILY SSF49401 224 375 1.29E-10 T 28-03-2018 IPR008966 Adhesion domain WM46_RS04195 6bce4ea9e14c3f54ac38b99eb42ced6f 378 Gene3D G3DSA:2.60.40.1090 237 376 1.1E-16 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS04195 6bce4ea9e14c3f54ac38b99eb42ced6f 378 Pfam PF00419 Fimbrial protein 227 377 3.3E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 362 376 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 Gene3D G3DSA:3.90.100.10 595 712 3.7E-36 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 14 124 4.5E-29 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 SUPERFAMILY SSF55904 567 707 8.5E-44 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 130 544 1.4E-192 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 PIRSF PIRSF009393 1 712 1.0E-279 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 Gene3D G3DSA:3.90.1150.10 425 594 6.8E-54 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 570 700 2.1E-47 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 SUPERFAMILY SSF53383 130 562 5.57E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS13890 b0731bf08b87a2150c027cc9fead8a10 712 Gene3D G3DSA:3.40.640.10 130 424 1.1E-30 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 424 1.8E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12910 f271400428eca2555e827bf7f489864d 431 SMART SM00387 313 425 3.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12910 f271400428eca2555e827bf7f489864d 431 SMART SM00388 203 269 7.2E-21 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 268 7.2E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 SMART SM00091 98 165 1.3E-5 T 28-03-2018 IPR000014 PAS domain WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Pfam PF00989 PAS fold 99 194 4.6E-11 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Gene3D G3DSA:3.30.450.20 97 208 1.1E-13 T 28-03-2018 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 SUPERFAMILY SSF55785 87 195 7.68E-10 T 28-03-2018 IPR000014 PAS domain WM46_RS12910 f271400428eca2555e827bf7f489864d 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 8.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 8.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 8.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 422 8.0E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Pfam PF11808 Domain of unknown function (DUF3329) 6 91 3.1E-26 T 28-03-2018 IPR021766 Protein of unknown function DUF3329 GO:0004673 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 95 420 6.6E-137 T 28-03-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Gene3D G3DSA:3.30.565.10 274 431 3.1E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12910 f271400428eca2555e827bf7f489864d 431 Gene3D G3DSA:1.10.287.130 209 265 4.0E-17 T 28-03-2018 WM46_RS12910 f271400428eca2555e827bf7f489864d 431 SUPERFAMILY SSF55874 259 423 1.18E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12910 f271400428eca2555e827bf7f489864d 431 SUPERFAMILY SSF47384 190 268 8.24E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS25380 8ad3cd62d65e8b597cb1dbd8f918ecf1 116 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 113 5.8E-30 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS25380 8ad3cd62d65e8b597cb1dbd8f918ecf1 116 PIRSF PIRSF004761 1 116 1.6E-36 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS25380 8ad3cd62d65e8b597cb1dbd8f918ecf1 116 Hamap MF_00213 Probable hydrogenase nickel incorporation protein HypA [hypA]. 1 114 22.995 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS25380 8ad3cd62d65e8b597cb1dbd8f918ecf1 116 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 116 3.1E-42 T 28-03-2018 IPR000688 Hydrogenase nickel incorporation protein HypA/HybF GO:0006464|GO:0016151 WM46_RS25380 8ad3cd62d65e8b597cb1dbd8f918ecf1 116 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 28-03-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 76 85 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 SUPERFAMILY SSF53187 10 185 7.8E-54 T 28-03-2018 WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 SUPERFAMILY SSF53187 316 399 7.8E-54 T 28-03-2018 WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 Pfam PF01546 Peptidase family M20/M25/M40 78 395 9.6E-24 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 Pfam PF07687 Peptidase dimerisation domain 183 282 1.4E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 TIGRFAM TIGR03526 selenium_YgeY: putative selenium metabolism hydrolase 8 400 3.9E-219 T 28-03-2018 IPR017706 Peptidase M20/DapE, YgeY WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 SUPERFAMILY SSF55031 186 282 3.59E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS24355 d2b968976a4603ab6385b6d4f3f62dcf 403 Gene3D G3DSA:3.40.630.10 6 287 1.5E-49 T 28-03-2018 WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 Gene3D G3DSA:3.40.50.300 1 232 4.4E-64 T 28-03-2018 WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 SMART SM00382 33 227 2.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 Pfam PF02687 FtsX-like permease family 549 636 1.0E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 Pfam PF12704 MacB-like periplasmic core domain 269 485 3.5E-29 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 SUPERFAMILY SSF52540 4 225 3.17E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22110 78f3226f285b7be17436fd54b139cf1a 643 Pfam PF00005 ABC transporter 24 172 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS00185 a123769989d518b06e2aaa859a1aea54 82 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 28-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS00185 a123769989d518b06e2aaa859a1aea54 82 Gene3D G3DSA:3.30.1320.10 1 79 7.4E-33 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00185 a123769989d518b06e2aaa859a1aea54 82 Pfam PF00886 Ribosomal protein S16 8 68 3.3E-24 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00185 a123769989d518b06e2aaa859a1aea54 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 2.4E-28 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00185 a123769989d518b06e2aaa859a1aea54 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.041 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00185 a123769989d518b06e2aaa859a1aea54 82 SUPERFAMILY SSF54565 1 76 8.11E-29 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS06340 77f9221767001b839fe0848d3318d223 548 Gene3D G3DSA:1.20.1250.20 33 226 3.9E-8 T 28-03-2018 WM46_RS06340 77f9221767001b839fe0848d3318d223 548 SUPERFAMILY SSF103473 41 225 8.37E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06340 77f9221767001b839fe0848d3318d223 548 SUPERFAMILY SSF103473 275 446 8.37E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06340 77f9221767001b839fe0848d3318d223 548 SUPERFAMILY SSF103473 506 533 8.37E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06340 77f9221767001b839fe0848d3318d223 548 Gene3D G3DSA:1.20.1250.20 283 540 4.0E-9 T 28-03-2018 WM46_RS06340 77f9221767001b839fe0848d3318d223 548 Pfam PF07690 Major Facilitator Superfamily 46 436 8.7E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 306 1.3E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 324 1.8E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 Gene3D G3DSA:3.40.50.300 9 336 3.0E-79 T 28-03-2018 WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 SUPERFAMILY SSF52540 13 261 5.44E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 SMART SM00382 47 239 4.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS20620 b521a493bb690965f9c3af67a2cd0213 337 Pfam PF00005 ABC transporter 38 189 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS12835 cd81dd015e9c61ffc948bf0c5c581fa8 200 SUPERFAMILY SSF52833 1 193 1.96E-65 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS12835 cd81dd015e9c61ffc948bf0c5c581fa8 200 Pfam PF00578 AhpC/TSA family 5 139 5.2E-34 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS12835 cd81dd015e9c61ffc948bf0c5c581fa8 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 194 5.1E-12 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS12835 cd81dd015e9c61ffc948bf0c5c581fa8 200 PIRSF PIRSF000239 1 198 7.6E-59 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS12835 cd81dd015e9c61ffc948bf0c5c581fa8 200 Gene3D G3DSA:3.40.30.10 3 161 2.2E-39 T 28-03-2018 WM46_RS12835 cd81dd015e9c61ffc948bf0c5c581fa8 200 Gene3D G3DSA:3.30.1020.10 162 198 6.7E-15 T 28-03-2018 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 283 1.2E-109 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 PIRSF PIRSF001359 1 284 5.2E-114 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 283 1.2E-96 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 71 84 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 TIGRFAM TIGR01858 tag_bisphos_ald: class II aldolase, tagatose bisphosphate family 3 283 2.8E-159 T 28-03-2018 IPR011288 D-tagatose-bisphosphate aldolase, class II, subunit KbaY/GatY GO:0005975|GO:0008270|GO:0009025 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 SUPERFAMILY SSF51569 3 283 2.2E-97 T 28-03-2018 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 Gene3D G3DSA:3.20.20.70 1 286 1.1E-103 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 Hamap MF_01293 D-tagatose-1,6-bisphosphate aldolase subunit KbaY [kbaY]. 1 286 73.005 T 28-03-2018 IPR023788 D-tagatose-bisphosphate aldolase, class II, subunit KbaY GO:0005975|GO:0008270|GO:0009025|GO:2001059 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 WM46_RS16625 421287e2c6dde469dab7946afeaec18a 293 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS22555 ae034ea02570a409fe487aeaad2a095c 607 Pfam PF13175 AAA ATPase domain 1 400 4.7E-41 T 28-03-2018 WM46_RS22555 ae034ea02570a409fe487aeaad2a095c 607 SUPERFAMILY SSF52540 1 133 2.09E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22555 ae034ea02570a409fe487aeaad2a095c 607 SUPERFAMILY SSF52540 230 408 2.09E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22555 ae034ea02570a409fe487aeaad2a095c 607 Gene3D G3DSA:3.40.50.300 1 439 3.8E-25 T 28-03-2018 WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Gene3D G3DSA:3.30.70.20 131 160 2.9E-9 T 28-03-2018 WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Gene3D G3DSA:3.30.70.20 40 72 0.04 T 28-03-2018 WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Gene3D G3DSA:3.30.70.20 161 185 3.3E-11 T 28-03-2018 WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 156 167 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Gene3D G3DSA:3.30.70.20 186 207 4.8E-5 T 28-03-2018 WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Gene3D G3DSA:3.30.70.20 73 130 9.3E-11 T 28-03-2018 WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Pfam PF13247 4Fe-4S dicluster domain 116 193 2.0E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 Pfam PF12800 4Fe-4S binding domain 67 78 0.12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS07755 c6c1b5d3c60dc7946b0573a76883c475 208 SUPERFAMILY SSF54862 61 205 4.05E-38 T 28-03-2018 WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 Hamap MF_01584 UPF0502 protein YceH [yceH]. 5 211 34.353 T 28-03-2018 IPR007432 Protein of unknown function DUF480 WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 Gene3D G3DSA:1.10.10.10 97 171 8.3E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 Gene3D G3DSA:1.10.10.10 2 87 9.9E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 Pfam PF04337 Protein of unknown function, DUF480 5 158 1.7E-62 T 28-03-2018 IPR007432 Protein of unknown function DUF480 WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 Gene3D G3DSA:1.20.5.10 183 215 0.0015 T 28-03-2018 WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 SUPERFAMILY SSF46785 2 84 8.16E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08825 c7257adc014dbe6599223337ba17c715 215 SUPERFAMILY SSF46785 90 172 2.09E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24330 4da933c96d9f78708c2e8c50a4d58e38 190 Gene3D G3DSA:3.90.550.10 1 190 3.5E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS24330 4da933c96d9f78708c2e8c50a4d58e38 190 SUPERFAMILY SSF53448 1 188 3.15E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS24330 4da933c96d9f78708c2e8c50a4d58e38 190 TIGRFAM TIGR03310 matur_MocA_YgfJ: molybdenum cofactor cytidylyltransferase 5 184 2.5E-58 T 28-03-2018 IPR017696 Molybdenum cofactor cytidylyltransferase KEGG: 00790+2.7.7.76|MetaCyc: PWY-6476 WM46_RS24330 4da933c96d9f78708c2e8c50a4d58e38 190 Pfam PF12804 MobA-like NTP transferase domain 6 147 1.9E-24 T 28-03-2018 IPR025877 MobA-like NTP transferase WM46_RS01145 2e6c68b72582270465fe6183a2a808c9 253 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 9 249 29.165 T 28-03-2018 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 WM46_RS01145 2e6c68b72582270465fe6183a2a808c9 253 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 15 231 4.4E-43 T 28-03-2018 WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 Pfam PF00072 Response regulator receiver domain 8 117 4.3E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 Gene3D G3DSA:3.40.50.2300 1 149 6.5E-26 T 28-03-2018 WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 Pfam PF12431 Transcriptional regulator 134 162 6.6E-10 T 28-03-2018 IPR028141 Transcriptional regulator WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 Gene3D G3DSA:1.10.10.10 163 223 0.0014 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 SUPERFAMILY SSF52172 3 156 1.24E-30 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 PIRSF PIRSF006171 3 225 4.7E-75 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 WM46_RS11460 0ad9c8696fa762a5b1b898957ba6c8c0 225 SMART SM00448 5 118 1.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 6.6E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 SUPERFAMILY SSF54814 182 297 1.96E-40 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 Hamap MF_00367 GTPase Era [era]. 6 297 35.293 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 Gene3D G3DSA:3.40.50.300 26 180 8.0E-27 T 28-03-2018 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 171 1.3E-41 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 Gene3D G3DSA:3.40.50.300 8 25 0.0071 T 28-03-2018 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 SUPERFAMILY SSF52540 11 205 1.26E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 Pfam PF07650 KH domain 209 285 1.8E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 Gene3D G3DSA:3.30.300.20 186 300 1.2E-42 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS00410 a7f57e87e415506eb9554d08f1749e27 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 280 1.9E-118 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS19485 9070442aebc29f3139d2a12d0ac0ebb9 207 SUPERFAMILY SSF53335 4 205 5.53E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS19485 9070442aebc29f3139d2a12d0ac0ebb9 207 PIRSF PIRSF003078 1 206 1.6E-65 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM46_RS19485 9070442aebc29f3139d2a12d0ac0ebb9 207 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 203 4.0E-60 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM46_RS19485 9070442aebc29f3139d2a12d0ac0ebb9 207 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 13 201 28.41 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM46_RS19485 9070442aebc29f3139d2a12d0ac0ebb9 207 Gene3D G3DSA:3.40.50.150 1 207 5.6E-37 T 28-03-2018 WM46_RS19485 9070442aebc29f3139d2a12d0ac0ebb9 207 Pfam PF02527 rRNA small subunit methyltransferase G 20 200 6.7E-65 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 1.6E-82 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 SUPERFAMILY SSF53748 3 383 7.42E-145 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 Pfam PF00162 Phosphoglycerate kinase 6 373 4.0E-140 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 39.141 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 Gene3D G3DSA:3.40.50.1260 3 174 4.7E-61 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 Gene3D G3DSA:3.40.50.1260 175 371 3.4E-76 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS14935 ae1a7425af9260f3a2bda1708005c7a5 387 PIRSF PIRSF000724 1 387 6.0E-134 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS10835 884fd05ebbd118851d7e05965893c19e 37 Pfam PF08173 Membrane bound YbgT-like protein 1 26 1.3E-14 T 28-03-2018 IPR012994 Membrane bound YbgT-like WM46_RS10835 884fd05ebbd118851d7e05965893c19e 37 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 29 3.4E-20 T 28-03-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 Gene3D G3DSA:3.20.20.70 1 220 1.4E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 4.2E-96 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 SUPERFAMILY SSF51366 3 218 2.66E-75 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 PIRSF PIRSF001461 1 225 6.4E-106 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS17760 d962a85a6b121e690b13764cf9e6f3b1 225 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 5.6E-91 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Gene3D G3DSA:3.30.70.20 114 152 1.6E-16 T 28-03-2018 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Gene3D G3DSA:3.30.70.20 9 41 0.0076 T 28-03-2018 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 PIRSF PIRSF036298 1 294 4.3E-160 T 28-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Gene3D G3DSA:3.30.70.20 153 255 1.9E-23 T 28-03-2018 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 290 1.9E-143 T 28-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Pfam PF13247 4Fe-4S dicluster domain 92 188 1.3E-25 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 2.7E-18 T 28-03-2018 IPR015246 Formate dehydrogenase, transmembrane WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Gene3D G3DSA:3.30.70.20 42 113 2.0E-20 T 28-03-2018 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 SUPERFAMILY SSF54862 26 275 4.08E-70 T 28-03-2018 WM46_RS06790 e0b581f4062708f44d961912426da5c5 294 Gene3D G3DSA:1.20.5.480 256 291 4.3E-22 T 28-03-2018 WM46_RS03630 9ced693007bea67d24fcbced060a8910 181 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 180 1.5E-62 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03630 9ced693007bea67d24fcbced060a8910 181 Gene3D G3DSA:3.40.50.300 2 181 1.6E-63 T 28-03-2018 WM46_RS03630 9ced693007bea67d24fcbced060a8910 181 SUPERFAMILY SSF52540 2 181 1.03E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03630 9ced693007bea67d24fcbced060a8910 181 PIRSF PIRSF006135 1 181 3.5E-63 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 SMART SM01134 73 234 4.4E-57 T 28-03-2018 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 SMART SM00420 8 57 1.5E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 SUPERFAMILY SSF100950 74 236 3.35E-30 T 28-03-2018 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 Gene3D G3DSA:3.40.50.1360 77 235 1.7E-28 T 28-03-2018 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 Gene3D G3DSA:1.10.10.10 1 76 5.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 Pfam PF08220 DeoR-like helix-turn-helix domain 8 58 3.4E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS10235 5ab293319a6067ee7decdb8a3fae4cb2 252 Pfam PF00455 DeoR C terminal sensor domain 76 232 2.4E-44 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS08475 9d6535a151e515046df3428f76d90edf 153 Gene3D G3DSA:3.90.79.10 1 147 2.0E-28 T 28-03-2018 WM46_RS08475 9d6535a151e515046df3428f76d90edf 153 SUPERFAMILY SSF55811 2 136 6.77E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS08475 9d6535a151e515046df3428f76d90edf 153 PRINTS PR00502 NUDIX hydrolase family signature 45 60 1.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS08475 9d6535a151e515046df3428f76d90edf 153 PRINTS PR00502 NUDIX hydrolase family signature 31 45 1.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS08475 9d6535a151e515046df3428f76d90edf 153 Pfam PF00293 NUDIX domain 4 112 8.0E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS08475 9d6535a151e515046df3428f76d90edf 153 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS04505 b13d5fe411a5a7cc6d65e57eedf91920 172 Pfam PF13392 HNH endonuclease 60 101 1.4E-11 T 28-03-2018 IPR003615 HNH nuclease WM46_RS04505 b13d5fe411a5a7cc6d65e57eedf91920 172 Pfam PF00847 AP2 domain 112 154 7.3E-9 T 28-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 WM46_RS04505 b13d5fe411a5a7cc6d65e57eedf91920 172 SUPERFAMILY SSF54060 11 105 5.41E-21 T 28-03-2018 WM46_RS04505 b13d5fe411a5a7cc6d65e57eedf91920 172 SMART SM00380 113 172 2.2E-5 T 28-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 WM46_RS04505 b13d5fe411a5a7cc6d65e57eedf91920 172 SUPERFAMILY SSF54171 112 171 1.24E-16 T 28-03-2018 IPR016177 DNA-binding domain GO:0003677 WM46_RS04505 b13d5fe411a5a7cc6d65e57eedf91920 172 Gene3D G3DSA:3.30.730.10 112 172 2.4E-16 T 28-03-2018 IPR001471 AP2/ERF domain GO:0003700|GO:0006355 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 ProSitePatterns PS00397 Site-specific recombinases active site. 9 17 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 Gene3D G3DSA:1.10.10.60 150 203 1.5E-9 T 28-03-2018 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 SMART SM00857 6 160 1.9E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 Pfam PF00239 Resolvase, N terminal domain 8 159 2.4E-28 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 ProSitePatterns PS00398 Site-specific recombinases signature 2. 65 77 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 SUPERFAMILY SSF53041 4 157 5.23E-29 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 Gene3D G3DSA:3.40.50.1390 5 128 3.9E-32 T 28-03-2018 WM46_RS12505 2683b2f41f526263e7f1d3efcc6aa1b8 209 Gene3D G3DSA:1.20.5.40 129 149 2.5E-4 T 28-03-2018 WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 SUPERFAMILY SSF55129 3 59 5.1E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 5.0E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 21.935 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 54 9.9E-19 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 PIRSF PIRSF002211 1 59 2.8E-29 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17455 4feffea74a7b86a96c498c445aa4994e 59 Gene3D G3DSA:3.30.1390.20 5 59 1.7E-23 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain WM46_RS00965 828ad09b28447d3c535012a238a2f349 267 Pfam PF01923 Cobalamin adenosyltransferase 95 246 1.3E-13 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 WM46_RS00965 828ad09b28447d3c535012a238a2f349 267 SUPERFAMILY SSF89028 93 249 1.26E-13 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 WM46_RS00965 828ad09b28447d3c535012a238a2f349 267 PIRSF PIRSF012294 1 255 5.6E-109 T 28-03-2018 IPR009194 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT-type GO:0005524|GO:0006580|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS00965 828ad09b28447d3c535012a238a2f349 267 Gene3D G3DSA:1.20.1200.10 94 253 8.3E-18 T 28-03-2018 WM46_RS04975 d48be1eee3ff327a2431d42a29a4b60a 566 Pfam PF12792 CSS motif domain associated with EAL 77 271 6.4E-38 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain WM46_RS04975 d48be1eee3ff327a2431d42a29a4b60a 566 SMART SM00052 299 540 2.2E-106 T 28-03-2018 IPR001633 EAL domain WM46_RS04975 d48be1eee3ff327a2431d42a29a4b60a 566 Pfam PF00563 EAL domain 307 535 9.6E-62 T 28-03-2018 IPR001633 EAL domain WM46_RS04975 d48be1eee3ff327a2431d42a29a4b60a 566 Gene3D G3DSA:3.20.20.450 295 550 1.1E-75 T 28-03-2018 IPR001633 EAL domain WM46_RS04975 d48be1eee3ff327a2431d42a29a4b60a 566 SUPERFAMILY SSF141868 306 548 3.14E-73 T 28-03-2018 IPR001633 EAL domain WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 114 1.3E-10 T 28-03-2018 IPR000014 PAS domain WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 280 309 6.7E-41 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 415 6.7E-41 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 357 384 6.7E-41 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 434 463 6.7E-41 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 SUPERFAMILY SSF58104 232 505 8.89E-62 T 28-03-2018 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 SMART SM00283 259 506 7.6E-88 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 Gene3D G3DSA:3.40.50.10600 7 131 1.6E-27 T 28-03-2018 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 320 474 1.2E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 SMART SM00086 80 121 1.4E-5 T 28-03-2018 IPR001610 PAC motif WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 Gene3D G3DSA:1.10.287.950 212 314 1.3E-7 T 28-03-2018 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 Gene3D G3DSA:1.10.287.950 315 506 2.4E-41 T 28-03-2018 WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 SUPERFAMILY SSF55785 21 114 9.6E-25 T 28-03-2018 IPR000014 PAS domain WM46_RS16345 c16b2d8281256731fdd8b9930035806d 506 Pfam PF08447 PAS fold 31 113 1.4E-14 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 Gene3D G3DSA:1.10.10.60 259 308 7.9E-14 T 28-03-2018 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 252 294 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 SUPERFAMILY SSF46689 251 299 5.82E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 SMART SM00342 215 298 6.9E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 298 3.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 267 282 3.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 Pfam PF12833 Helix-turn-helix domain 221 299 2.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 SUPERFAMILY SSF46689 200 249 4.48E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 Gene3D G3DSA:2.60.120.10 35 258 1.6E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS05335 e5bc6603d66e6601a37be42342056658 309 SUPERFAMILY SSF51182 25 114 2.6E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS08705 25e249262f648da5a8e5a8afaa65f1fd 173 Pfam PF02620 Uncharacterized ACR, COG1399 62 171 2.0E-18 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD WM46_RS24410 406770cc47fd863d6813c63ef8e0bc5d 396 Gene3D G3DSA:1.50.10.10 26 396 1.3E-97 T 28-03-2018 WM46_RS24410 406770cc47fd863d6813c63ef8e0bc5d 396 Pfam PF07470 Glycosyl Hydrolase Family 88 61 388 3.9E-36 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 WM46_RS24410 406770cc47fd863d6813c63ef8e0bc5d 396 SUPERFAMILY SSF48208 27 396 3.78E-116 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 Gene3D G3DSA:3.40.190.10 179 261 3.8E-21 T 28-03-2018 WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 Gene3D G3DSA:3.40.190.10 90 178 1.2E-13 T 28-03-2018 WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 SUPERFAMILY SSF46785 5 89 2.72E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 Pfam PF03466 LysR substrate binding domain 89 287 7.1E-42 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 SUPERFAMILY SSF53850 89 289 5.79E-43 T 28-03-2018 WM46_RS24140 bfa8be284362053a6af0ea582bd8a304 299 Gene3D G3DSA:1.10.10.10 3 85 7.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02045 c78f0e4a9dbfed963a5298b13425b947 440 Pfam PF02667 Short chain fatty acid transporter 1 440 1.8E-225 T 28-03-2018 IPR006160 Short chain fatty acid transporter AtoE WM46_RS02045 c78f0e4a9dbfed963a5298b13425b947 440 TIGRFAM TIGR00366 TIGR00366: TIGR00366 family protein 4 428 1.6E-220 T 28-03-2018 IPR006161 Conserved hypothetical protein CHP00336 WM46_RS08665 ceee2c83e7b3a55e4fe9add03c1a2920 269 Gene3D G3DSA:3.30.470.10 1 109 1.9E-21 T 28-03-2018 WM46_RS08665 ceee2c83e7b3a55e4fe9add03c1a2920 269 Pfam PF01063 Amino-transferase class IV 24 246 9.7E-49 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 WM46_RS08665 ceee2c83e7b3a55e4fe9add03c1a2920 269 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 3 262 3.2E-111 T 28-03-2018 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543 WM46_RS08665 ceee2c83e7b3a55e4fe9add03c1a2920 269 ProSitePatterns PS00770 Aminotransferases class-IV signature. 173 202 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 WM46_RS08665 ceee2c83e7b3a55e4fe9add03c1a2920 269 SUPERFAMILY SSF56752 2 262 3.14E-67 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 WM46_RS08665 ceee2c83e7b3a55e4fe9add03c1a2920 269 Gene3D G3DSA:3.20.10.10 111 246 1.1E-33 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Gene3D G3DSA:3.30.2090.10 723 811 6.3E-18 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82693 810 858 2.88E-23 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82693 673 723 2.88E-23 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82866 842 1027 8.37E-44 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 3.8E-116 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82714 182 271 2.49E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Gene3D G3DSA:1.20.1640.10 829 1032 9.3E-37 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Gene3D G3DSA:1.20.1640.10 287 510 6.4E-45 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1035 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Pfam PF00873 AcrB/AcrD/AcrF family 1 1029 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Gene3D G3DSA:3.30.70.1430 38 140 4.3E-30 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82866 296 497 4.45E-48 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82693 566 670 1.15E-33 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82693 38 132 6.8E-28 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Gene3D G3DSA:3.30.70.1430 568 669 5.5E-21 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82693 136 182 6.02E-27 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82693 274 330 6.02E-27 T 28-03-2018 WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 Gene3D G3DSA:3.30.2090.10 180 275 3.5E-15 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS17275 d331f64b55a1fd3df3b2bd8808d05496 1037 SUPERFAMILY SSF82714 724 810 2.88E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Gene3D G3DSA:1.10.10.10 1 64 1.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 81 317 1.6E-84 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 SUPERFAMILY SSF50037 271 317 1.6E-10 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Pfam PF03099 Biotin/lipoate A/B protein ligase family 84 208 3.6E-24 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Pfam PF02237 Biotin protein ligase C terminal domain 271 317 8.4E-11 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Gene3D G3DSA:2.30.30.100 272 318 9.4E-14 T 28-03-2018 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 317 32.637 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Gene3D G3DSA:3.30.930.10 65 270 1.1E-59 T 28-03-2018 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 6 76 4.2E-28 T 28-03-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 Pfam PF08279 HTH domain 10 58 1.0E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 SUPERFAMILY SSF46785 4 60 1.52E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21120 95a4fdff48cdba95233bab35b75bcac6 320 SUPERFAMILY SSF55681 73 268 2.11E-57 T 28-03-2018 WM46_RS09935 cdfe0406679cbd045e712be30a83e458 203 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 1 203 4.5E-121 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 WM46_RS09935 cdfe0406679cbd045e712be30a83e458 203 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 9 201 32.53 T 28-03-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 WM46_RS09935 cdfe0406679cbd045e712be30a83e458 203 SUPERFAMILY SSF89392 22 202 8.24E-57 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX WM46_RS09935 cdfe0406679cbd045e712be30a83e458 203 Gene3D G3DSA:2.50.20.10 19 202 2.9E-40 T 28-03-2018 WM46_RS09935 cdfe0406679cbd045e712be30a83e458 203 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 33 191 8.1E-58 T 28-03-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like WM46_RS20560 ed71486de77de7c7e5e70976534fd2c6 192 Gene3D G3DSA:1.10.340.30 1 182 2.4E-83 T 28-03-2018 WM46_RS20560 ed71486de77de7c7e5e70976534fd2c6 192 SUPERFAMILY SSF48150 2 183 1.57E-81 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM46_RS20560 ed71486de77de7c7e5e70976534fd2c6 192 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 2 181 1.4E-91 T 28-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 WM46_RS20560 ed71486de77de7c7e5e70976534fd2c6 192 Pfam PF03352 Methyladenine glycosylase 6 182 2.4E-80 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 WM46_RS08655 b1c70df010dcd57f92a59d32acaca5cf 213 ProSitePatterns PS01331 Thymidylate kinase signature. 97 109 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 WM46_RS08655 b1c70df010dcd57f92a59d32acaca5cf 213 SUPERFAMILY SSF52540 1 209 1.11E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08655 b1c70df010dcd57f92a59d32acaca5cf 213 Gene3D G3DSA:3.40.50.300 1 211 6.5E-48 T 28-03-2018 WM46_RS08655 b1c70df010dcd57f92a59d32acaca5cf 213 Pfam PF02223 Thymidylate kinase 8 200 2.5E-59 T 28-03-2018 WM46_RS08655 b1c70df010dcd57f92a59d32acaca5cf 213 Hamap MF_00165 Thymidylate kinase [tmk]. 4 208 28.609 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 WM46_RS08655 b1c70df010dcd57f92a59d32acaca5cf 213 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 200 5.4E-67 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 SUPERFAMILY SSF55658 1 57 3.14E-19 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.672 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 Gene3D G3DSA:3.40.5.10 1 49 6.1E-23 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 2.1E-58 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 SUPERFAMILY SSF55653 60 149 7.85E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 3.2E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 Gene3D G3DSA:3.10.430.100 63 148 2.0E-26 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal WM46_RS23000 91690b4282e8396eba41cc82b23018cd 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 3.9E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS11915 07b904428f4f16a11f09a383c54ad09a 390 SUPERFAMILY SSF103473 3 377 8.5E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS11915 07b904428f4f16a11f09a383c54ad09a 390 Gene3D G3DSA:1.20.1250.20 2 188 4.1E-23 T 28-03-2018 WM46_RS11915 07b904428f4f16a11f09a383c54ad09a 390 Gene3D G3DSA:1.20.1250.20 189 382 7.3E-13 T 28-03-2018 WM46_RS11915 07b904428f4f16a11f09a383c54ad09a 390 Pfam PF07690 Major Facilitator Superfamily 8 342 8.2E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Pfam PF00912 Transglycosylase 208 379 1.8E-54 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 SUPERFAMILY SSF56601 411 783 1.56E-104 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 SUPERFAMILY SSF56601 361 383 1.56E-104 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Gene3D G3DSA:3.30.2060.10 111 197 4.8E-27 T 28-03-2018 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Pfam PF00905 Penicillin binding protein transpeptidase domain 472 714 1.5E-25 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Pfam PF14814 Bifunctional transglycosylase second domain 112 196 2.6E-27 T 28-03-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 PIRSF PIRSF002799 10 842 0.0 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Gene3D G3DSA:1.20.5.100 56 94 1.0E-16 T 28-03-2018 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 SUPERFAMILY SSF53955 196 402 1.74E-65 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Pfam PF14812 Transmembrane domain of transglycosylase PBP1 at N-terminal 1 78 1.4E-27 T 28-03-2018 IPR032730 Transglycosylase PBP1b, N-terminal transmembrane domain WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 67 794 0.0 T 28-03-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00500+2.4.1.12|KEGG: 00550+2.4.1.129|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Gene3D G3DSA:3.40.710.10 403 830 1.8E-97 T 28-03-2018 WM46_RS14070 42afade629c6ff9c7e979262704f4d62 843 Gene3D G3DSA:1.10.3810.10 198 396 7.5E-62 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS02300 731f77648927282b62ea2bca7e68a59d 518 SUPERFAMILY SSF141868 267 513 1.18E-71 T 28-03-2018 IPR001633 EAL domain WM46_RS02300 731f77648927282b62ea2bca7e68a59d 518 SMART SM00052 260 505 1.7E-98 T 28-03-2018 IPR001633 EAL domain WM46_RS02300 731f77648927282b62ea2bca7e68a59d 518 Pfam PF00563 EAL domain 268 500 6.8E-68 T 28-03-2018 IPR001633 EAL domain WM46_RS02300 731f77648927282b62ea2bca7e68a59d 518 Pfam PF12792 CSS motif domain associated with EAL 42 240 5.0E-39 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain WM46_RS02300 731f77648927282b62ea2bca7e68a59d 518 Gene3D G3DSA:3.20.20.450 260 516 8.0E-76 T 28-03-2018 IPR001633 EAL domain WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 Gene3D G3DSA:2.60.40.10 16 135 3.2E-34 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 PRINTS PR00969 Pili chaperone signature 93 110 2.2E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 PRINTS PR00969 Pili chaperone signature 63 84 2.2E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 PRINTS PR00969 Pili chaperone signature 153 168 2.2E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 PRINTS PR00969 Pili chaperone signature 116 131 2.2E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 PRINTS PR00969 Pili chaperone signature 17 26 2.2E-33 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 158 217 2.6E-16 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 SUPERFAMILY SSF49584 142 229 4.84E-23 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 16 134 1.4E-37 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 SUPERFAMILY SSF49354 16 134 7.33E-38 T 28-03-2018 IPR008962 PapD-like WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 92 109 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS22060 5fc05e0b6c759ba9197f829c467157bf 237 Gene3D G3DSA:2.60.40.10 138 229 4.2E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS10245 7c0265978a6a4872b8812d3cfbd3c29d 208 SUPERFAMILY SSF52833 1 85 1.97E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS10245 7c0265978a6a4872b8812d3cfbd3c29d 208 Pfam PF00043 Glutathione S-transferase, C-terminal domain 121 197 4.8E-9 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS10245 7c0265978a6a4872b8812d3cfbd3c29d 208 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 82 2.2E-14 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS10245 7c0265978a6a4872b8812d3cfbd3c29d 208 Gene3D G3DSA:3.40.30.10 1 99 5.7E-26 T 28-03-2018 WM46_RS10245 7c0265978a6a4872b8812d3cfbd3c29d 208 SUPERFAMILY SSF47616 83 203 5.85E-28 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS10245 7c0265978a6a4872b8812d3cfbd3c29d 208 Gene3D G3DSA:1.20.1050.10 100 203 3.1E-27 T 28-03-2018 WM46_RS26030 2ec61cd3a15d448d448f74293fd91780 331 Pfam PF00437 Type II/IV secretion system protein 10 311 8.7E-44 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 WM46_RS26030 2ec61cd3a15d448d448f74293fd91780 331 Gene3D G3DSA:3.30.450.90 6 102 4.8E-12 T 28-03-2018 WM46_RS26030 2ec61cd3a15d448d448f74293fd91780 331 Gene3D G3DSA:3.40.50.300 150 317 5.7E-11 T 28-03-2018 WM46_RS26030 2ec61cd3a15d448d448f74293fd91780 331 SUPERFAMILY SSF52540 6 309 2.0E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26030 2ec61cd3a15d448d448f74293fd91780 331 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 161 174 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS14775 ed0324f9c9eea6db3228505b4636a0ed 435 Pfam PF07690 Major Facilitator Superfamily 59 383 2.1E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14775 ed0324f9c9eea6db3228505b4636a0ed 435 Gene3D G3DSA:1.20.1250.20 14 228 5.0E-26 T 28-03-2018 WM46_RS14775 ed0324f9c9eea6db3228505b4636a0ed 435 Gene3D G3DSA:1.20.1250.20 237 434 5.9E-21 T 28-03-2018 WM46_RS14775 ed0324f9c9eea6db3228505b4636a0ed 435 SUPERFAMILY SSF103473 11 419 1.44E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS18025 ec92559923220de948f449d12c98d735 657 Hamap MF_01248 Glycogen debranching enzyme [glgX]. 1 657 71.928 T 28-03-2018 IPR022844 Glycogen debranching enzyme, bacterial GO:0004553|GO:0005977 WM46_RS18025 ec92559923220de948f449d12c98d735 657 SMART SM00642 130 558 1.8E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS18025 ec92559923220de948f449d12c98d735 657 SUPERFAMILY SSF51445 130 463 7.55E-128 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS18025 ec92559923220de948f449d12c98d735 657 SUPERFAMILY SSF51445 492 564 7.55E-128 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS18025 ec92559923220de948f449d12c98d735 657 Gene3D G3DSA:3.20.20.80 134 572 3.9E-108 T 28-03-2018 WM46_RS18025 ec92559923220de948f449d12c98d735 657 Pfam PF00128 Alpha amylase, catalytic domain 185 357 5.8E-10 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS18025 ec92559923220de948f449d12c98d735 657 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 7 631 6.8E-267 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 WM46_RS18025 ec92559923220de948f449d12c98d735 657 SUPERFAMILY SSF81296 7 144 5.32E-44 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS18025 ec92559923220de948f449d12c98d735 657 Gene3D G3DSA:2.60.40.10 1 133 2.0E-42 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS18025 ec92559923220de948f449d12c98d735 657 Gene3D G3DSA:2.60.40.1180 573 657 3.2E-7 T 28-03-2018 WM46_RS18025 ec92559923220de948f449d12c98d735 657 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 12 97 8.4E-19 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 WM46_RS03510 f642d3ec1f5a76ca5b661876545ec89d 222 Gene3D G3DSA:3.40.50.10150 48 219 3.3E-77 T 28-03-2018 IPR010254 B12-dependent dehydratases, beta subunit WM46_RS03510 f642d3ec1f5a76ca5b661876545ec89d 222 SUPERFAMILY SSF52968 45 222 4.32E-72 T 28-03-2018 IPR010254 B12-dependent dehydratases, beta subunit WM46_RS03510 f642d3ec1f5a76ca5b661876545ec89d 222 Pfam PF02288 Dehydratase medium subunit 67 179 1.4E-34 T 28-03-2018 IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor WM46_RS03510 f642d3ec1f5a76ca5b661876545ec89d 222 PIRSF PIRSF018506 1 222 4.0E-110 T 28-03-2018 IPR025541 Propanediol/glycerol dehydratase, medium subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013 WM46_RS15535 28dba85598107b30d221ef6a3db2b43e 261 Pfam PF02525 Flavodoxin-like fold 1 200 2.5E-40 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS15535 28dba85598107b30d221ef6a3db2b43e 261 Gene3D G3DSA:3.40.50.360 1 240 1.3E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS15535 28dba85598107b30d221ef6a3db2b43e 261 SUPERFAMILY SSF52218 1 221 6.48E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS02215 a5dcc9252bdef05d8d5b25e10a957c64 315 SUPERFAMILY SSF53448 1 232 3.28E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02215 a5dcc9252bdef05d8d5b25e10a957c64 315 Gene3D G3DSA:3.90.550.10 1 207 6.8E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02215 a5dcc9252bdef05d8d5b25e10a957c64 315 Pfam PF00535 Glycosyl transferase family 2 4 166 1.7E-28 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS20295 568ca5a7254921887ecd34b823e69649 158 SUPERFAMILY SSF75217 1 152 1.44E-45 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS20295 568ca5a7254921887ecd34b823e69649 158 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 34.464 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS20295 568ca5a7254921887ecd34b823e69649 158 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 153 5.6E-74 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS20295 568ca5a7254921887ecd34b823e69649 158 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.6E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM46_RS20295 568ca5a7254921887ecd34b823e69649 158 Gene3D G3DSA:3.40.1280.10 1 157 2.8E-37 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS20295 568ca5a7254921887ecd34b823e69649 158 PIRSF PIRSF029256 1 154 2.9E-71 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS05075 f78d9b67d7d6c25a8ff8ff08f89b1236 129 Pfam PF01042 Endoribonuclease L-PSP 15 127 2.6E-30 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family WM46_RS05075 f78d9b67d7d6c25a8ff8ff08f89b1236 129 Gene3D G3DSA:3.30.1330.40 11 129 1.9E-33 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like WM46_RS05075 f78d9b67d7d6c25a8ff8ff08f89b1236 129 SUPERFAMILY SSF55298 10 127 1.73E-35 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like WM46_RS21215 ae81e678ac650d092c3971fed4f20535 377 Pfam PF04055 Radical SAM superfamily 82 227 5.4E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS21215 ae81e678ac650d092c3971fed4f20535 377 SMART SM00876 258 361 4.0E-30 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS21215 ae81e678ac650d092c3971fed4f20535 377 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 258 360 4.3E-21 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS21215 ae81e678ac650d092c3971fed4f20535 377 Gene3D G3DSA:3.20.20.70 16 370 2.3E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS21215 ae81e678ac650d092c3971fed4f20535 377 SUPERFAMILY SSF102114 37 362 2.49E-52 T 28-03-2018 WM46_RS21215 ae81e678ac650d092c3971fed4f20535 377 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 3 368 7.1E-163 T 28-03-2018 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892 WM46_RS25040 6c1649dc5cd90b27042e78f42d4ff2f4 455 Gene3D G3DSA:1.10.4100.10 257 445 1.3E-32 T 28-03-2018 WM46_RS25040 6c1649dc5cd90b27042e78f42d4ff2f4 455 SUPERFAMILY SSF143548 16 158 1.07E-45 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 WM46_RS25040 6c1649dc5cd90b27042e78f42d4ff2f4 455 Pfam PF03315 Serine dehydratase beta chain 3 155 2.1E-56 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM46_RS25040 6c1649dc5cd90b27042e78f42d4ff2f4 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 8.5E-221 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM46_RS25040 6c1649dc5cd90b27042e78f42d4ff2f4 455 Pfam PF03313 Serine dehydratase alpha chain 184 448 3.1E-94 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit WM46_RS25040 6c1649dc5cd90b27042e78f42d4ff2f4 455 Gene3D G3DSA:3.30.1330.90 10 158 5.7E-51 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 3.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 3.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 3.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 3.6E-30 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 3.9E-145 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 SMART SM00840 341 402 4.4E-29 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 460 3.6E-200 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 SUPERFAMILY SSF52374 1 313 2.07E-105 T 28-03-2018 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 Gene3D G3DSA:3.40.50.620 1 305 7.6E-93 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 Gene3D G3DSA:1.20.120.640 306 392 7.2E-22 T 28-03-2018 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 Pfam PF09190 DALR domain 341 402 4.1E-25 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 SUPERFAMILY SSF47323 316 460 5.23E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS12210 752e4d12afe066338ae6ca011f681ba1 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 461 39.673 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 WM46_RS05230 ad629e57b4f9f35fcb58e2ba5be83d54 356 Gene3D G3DSA:3.40.50.10440 11 183 4.2E-67 T 28-03-2018 WM46_RS05230 ad629e57b4f9f35fcb58e2ba5be83d54 356 Pfam PF02733 Dak1 domain 18 350 1.1E-127 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM46_RS05230 ad629e57b4f9f35fcb58e2ba5be83d54 356 SUPERFAMILY SSF82549 10 355 8.89E-126 T 28-03-2018 WM46_RS05230 ad629e57b4f9f35fcb58e2ba5be83d54 356 Gene3D G3DSA:3.30.1180.20 184 356 2.0E-54 T 28-03-2018 WM46_RS05230 ad629e57b4f9f35fcb58e2ba5be83d54 356 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 351 2.5E-154 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 WM46_RS02910 dbd312cfc99e8d7e1d319096239beace 349 Gene3D G3DSA:3.40.50.720 1 239 3.2E-53 T 28-03-2018 WM46_RS02910 dbd312cfc99e8d7e1d319096239beace 349 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 333 7.8E-88 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02910 dbd312cfc99e8d7e1d319096239beace 349 SUPERFAMILY SSF51735 1 344 9.79E-88 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02910 dbd312cfc99e8d7e1d319096239beace 349 Gene3D G3DSA:3.90.25.10 240 343 3.2E-29 T 28-03-2018 WM46_RS02910 dbd312cfc99e8d7e1d319096239beace 349 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 345 4.1E-139 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 PRINTS PR00118 Beta-lactamase class A signature 62 79 1.1E-65 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 PRINTS PR00118 Beta-lactamase class A signature 30 54 1.1E-65 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 PRINTS PR00118 Beta-lactamase class A signature 140 164 1.1E-65 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 PRINTS PR00118 Beta-lactamase class A signature 166 191 1.1E-65 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 PRINTS PR00118 Beta-lactamase class A signature 104 129 1.1E-65 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 Gene3D G3DSA:3.40.710.10 27 199 2.3E-23 T 28-03-2018 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 SUPERFAMILY SSF56601 29 197 1.82E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 Pfam PF13354 Beta-lactamase enzyme family 49 197 5.4E-33 T 28-03-2018 WM46_RS26125 7b6f4bf1f82d28596feaeb7e9f983f0e 202 ProSitePatterns PS00146 Beta-lactamase class-A active site. 64 79 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 WM46_RS19025 57e23b058daaab5eb72b8f6f4b6861c0 253 Pfam PF01048 Phosphorylase superfamily 21 247 3.7E-41 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS19025 57e23b058daaab5eb72b8f6f4b6861c0 253 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 6 253 5.4E-130 T 28-03-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 WM46_RS19025 57e23b058daaab5eb72b8f6f4b6861c0 253 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 66 81 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS19025 57e23b058daaab5eb72b8f6f4b6861c0 253 Gene3D G3DSA:3.40.50.1580 3 253 2.0E-55 T 28-03-2018 WM46_RS19025 57e23b058daaab5eb72b8f6f4b6861c0 253 SUPERFAMILY SSF53167 6 250 4.58E-73 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS12185 983234cff229828f5099dff02467fe55 288 SUPERFAMILY SSF53223 3 122 5.85E-41 T 28-03-2018 WM46_RS12185 983234cff229828f5099dff02467fe55 288 Gene3D G3DSA:3.40.50.720 141 264 7.5E-39 T 28-03-2018 WM46_RS12185 983234cff229828f5099dff02467fe55 288 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.921 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 SUPERFAMILY SSF51735 123 282 2.27E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12185 983234cff229828f5099dff02467fe55 288 Gene3D G3DSA:3.40.50.10860 11 140 1.1E-50 T 28-03-2018 WM46_RS12185 983234cff229828f5099dff02467fe55 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 279 4.1E-68 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 2.0E-40 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS12185 983234cff229828f5099dff02467fe55 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 1.1E-88 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 WM46_RS11635 229eb6e8bf0aaaffda1627e14ea88d6c 402 SUPERFAMILY SSF81296 7 156 8.82E-48 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS11635 229eb6e8bf0aaaffda1627e14ea88d6c 402 Gene3D G3DSA:3.40.50.1820 151 401 8.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11635 229eb6e8bf0aaaffda1627e14ea88d6c 402 SUPERFAMILY SSF53474 161 399 3.03E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11635 229eb6e8bf0aaaffda1627e14ea88d6c 402 Gene3D G3DSA:2.60.40.10 5 148 2.6E-43 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS11635 229eb6e8bf0aaaffda1627e14ea88d6c 402 Pfam PF11806 Domain of unknown function (DUF3327) 31 161 8.7E-44 T 28-03-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 WM46_RS11635 229eb6e8bf0aaaffda1627e14ea88d6c 402 Pfam PF00756 Putative esterase 178 397 1.7E-39 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 51 70 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Pfam PF01568 Molydopterin dinucleotide binding domain 681 792 8.0E-25 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 SUPERFAMILY SSF53706 48 683 3.93E-159 T 28-03-2018 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 SMART SM00926 46 106 1.6E-10 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Gene3D G3DSA:2.40.40.20 662 800 6.6E-32 T 28-03-2018 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 SUPERFAMILY SSF50692 626 800 2.71E-38 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Gene3D G3DSA:3.40.228.10 581 661 6.2E-10 T 28-03-2018 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Gene3D G3DSA:3.40.50.740 111 318 1.3E-31 T 28-03-2018 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 1 800 0.0 T 28-03-2018 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Pfam PF00384 Molybdopterin oxidoreductase 109 558 3.4E-75 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 500 517 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Gene3D G3DSA:2.20.25.90 40 110 6.9E-16 T 28-03-2018 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 47 106 9.7E-9 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS22015 78a2b469ff2f0f2cb1c8016a9de4339a 800 Gene3D G3DSA:3.40.50.740 319 580 7.8E-37 T 28-03-2018 WM46_RS16970 2866676944a273c77ac508f6721cf2b4 217 PIRSF PIRSF006320 1 216 8.7E-104 T 28-03-2018 IPR026041 Glyoxalase ElbB WM46_RS16970 2866676944a273c77ac508f6721cf2b4 217 Gene3D G3DSA:3.40.50.880 2 217 9.3E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS16970 2866676944a273c77ac508f6721cf2b4 217 SUPERFAMILY SSF52317 1 216 3.21E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 SUPERFAMILY SSF48498 81 194 1.62E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 2.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 Gene3D G3DSA:1.10.357.10 61 195 4.5E-23 T 28-03-2018 WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 Gene3D G3DSA:1.10.10.60 7 60 1.2E-14 T 28-03-2018 WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 Pfam PF16925 Bacterial transcriptional repressor C-terminal 84 189 2.6E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS07545 86f51f290011b223b908d57fe8f12bbf 199 SUPERFAMILY SSF46689 8 78 2.46E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06855 4ededf3c6f5e938c7459e5796f7d3971 516 PIRSF PIRSF002741 8 513 1.1E-108 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS06855 4ededf3c6f5e938c7459e5796f7d3971 516 Gene3D G3DSA:3.10.105.10 291 487 9.0E-53 T 28-03-2018 WM46_RS06855 4ededf3c6f5e938c7459e5796f7d3971 516 SUPERFAMILY SSF53850 30 507 7.97E-133 T 28-03-2018 WM46_RS06855 4ededf3c6f5e938c7459e5796f7d3971 516 Gene3D G3DSA:3.90.76.10 54 152 1.1E-26 T 28-03-2018 WM46_RS06855 4ededf3c6f5e938c7459e5796f7d3971 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 432 3.5E-92 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS06855 4ededf3c6f5e938c7459e5796f7d3971 516 Gene3D G3DSA:3.40.190.10 153 290 4.4E-40 T 28-03-2018 WM46_RS24075 5068a6306eedfaecd810efecbbe9fc36 357 SUPERFAMILY SSF52151 21 279 3.66E-43 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 WM46_RS24075 5068a6306eedfaecd810efecbbe9fc36 357 Gene3D G3DSA:3.40.1090.10 16 238 3.9E-29 T 28-03-2018 WM46_RS24075 5068a6306eedfaecd810efecbbe9fc36 357 Pfam PF01734 Patatin-like phospholipase 27 195 5.0E-21 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM46_RS25730 4d2fc98dbf629c6ad5569b76e58bead4 422 Gene3D G3DSA:3.50.50.60 2 86 0.019 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS25730 4d2fc98dbf629c6ad5569b76e58bead4 422 Pfam PF01266 FAD dependent oxidoreductase 3 390 4.1E-70 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS25730 4d2fc98dbf629c6ad5569b76e58bead4 422 Gene3D G3DSA:3.30.9.10 87 201 1.8E-17 T 28-03-2018 WM46_RS25730 4d2fc98dbf629c6ad5569b76e58bead4 422 Gene3D G3DSA:3.30.9.10 203 352 8.7E-20 T 28-03-2018 WM46_RS25730 4d2fc98dbf629c6ad5569b76e58bead4 422 Hamap MF_00990 L-2-hydroxyglutarate oxidase LhgO [lhgO]. 1 422 87.267 T 28-03-2018 IPR030862 L-2-hydroxyglutarate oxidase LhgO GO:0034419 KEGG: 00630+1.1.3.15|MetaCyc: PWY-181 WM46_RS25730 4d2fc98dbf629c6ad5569b76e58bead4 422 SUPERFAMILY SSF51905 1 286 2.81E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS09225 0880ce767447c6fca77d21672694b810 207 Pfam PF13462 Thioredoxin 45 198 3.7E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS09225 0880ce767447c6fca77d21672694b810 207 Gene3D G3DSA:3.40.30.10 35 207 1.1E-35 T 28-03-2018 WM46_RS09225 0880ce767447c6fca77d21672694b810 207 ProSitePatterns PS00194 Thioredoxin family active site. 58 76 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS09225 0880ce767447c6fca77d21672694b810 207 SUPERFAMILY SSF52833 36 198 2.94E-37 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 Gene3D G3DSA:3.40.50.2300 1 134 1.7E-30 T 28-03-2018 WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 Gene3D G3DSA:2.20.25.10 203 238 7.1E-10 T 28-03-2018 WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 Pfam PF00072 Response regulator receiver domain 4 112 1.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 Gene3D G3DSA:2.40.50.40 135 200 1.5E-6 T 28-03-2018 WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 SMART SM00850 143 238 6.7E-27 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 SUPERFAMILY SSF52172 1 123 3.56E-32 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 Pfam PF04397 LytTr DNA-binding domain 144 237 4.7E-24 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 WM46_RS02610 398a370cb13002c15f75c25b42fb3803 239 SMART SM00448 2 112 1.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS05715 c10a8911d86dfa3c94c5369daeb81f1e 302 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 275 2.4E-115 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 WM46_RS05715 c10a8911d86dfa3c94c5369daeb81f1e 302 Pfam PF00483 Nucleotidyl transferase 10 276 4.0E-25 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM46_RS05715 c10a8911d86dfa3c94c5369daeb81f1e 302 Gene3D G3DSA:3.90.550.10 1 302 1.3E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS05715 c10a8911d86dfa3c94c5369daeb81f1e 302 SUPERFAMILY SSF53448 9 291 2.48E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS07355 6411daae521b7deebe1e7ea7c9f44edb 111 Pfam PF06942 GlpM protein 5 111 2.5E-51 T 28-03-2018 IPR009707 Membrane protein GlpM/YdgC WM46_RS07355 6411daae521b7deebe1e7ea7c9f44edb 111 ProDom PD028709 MEMBRANE INNER YDGC GLPM ALGINATE BIOSYNTHESIS TRANSMEMBRANE REQUIRED FOR UNCHARACTERIZED 23 111 2.0E-40 T 28-03-2018 IPR009707 Membrane protein GlpM/YdgC WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 SMART SM00922 184 284 1.2E-15 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 SUPERFAMILY SSF54826 7 136 1.37E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 Gene3D G3DSA:3.20.20.120 144 413 4.3E-54 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 Pfam PF13378 Enolase C-terminal domain-like 187 404 6.4E-39 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 Gene3D G3DSA:3.30.390.10 8 143 2.7E-35 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 SUPERFAMILY SSF51604 138 415 1.06E-82 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 136 2.6E-8 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS25090 7e9a0a25fee23ca635206e93c7f0d22b 446 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 111 136 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 SUPERFAMILY SSF48452 141 256 1.76E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Pfam PF16331 TolA binding protein trimerisation 37 111 4.8E-24 T 28-03-2018 IPR032519 YbgF, trimerisation domain GO:0070206 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 6 264 19.837 T 28-03-2018 IPR034706 Cell division coordinator CpoB GO:0051301 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 145 261 1.2E-39 T 28-03-2018 IPR014162 Cell division coordinator CpoB, C-terminal WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Gene3D G3DSA:1.25.40.10 192 227 7.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Gene3D G3DSA:1.25.40.10 139 191 0.0073 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Gene3D G3DSA:1.25.40.10 228 264 2.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Pfam PF13174 Tetratricopeptide repeat 219 251 6.1E-7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Gene3D G3DSA:1.20.5.50 35 81 1.9E-5 T 28-03-2018 WM46_RS10795 1ed6e60ae3de4d53ec027cc86dccca70 264 Pfam PF13432 Tetratricopeptide repeat 160 215 4.0E-5 T 28-03-2018 WM46_RS03315 a3c2916f14b78aea25684314329fdd09 65 Pfam PF10948 Protein of unknown function (DUF2635) 3 47 3.9E-20 T 28-03-2018 IPR024400 Protein of unknown function DUF2635 WM46_RS03315 a3c2916f14b78aea25684314329fdd09 65 ProDom PD027295 GP38 FLUMU BACTERIOPHAGE MU-LIKE ECS4978 SB12 PHAGE ORF10 PROPHAGE 1 42 3.0E-10 T 28-03-2018 IPR024400 Protein of unknown function DUF2635 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Hamap MF_01621 Fatty acid oxidation complex subunit alpha [fadB]. 1 715 53.497 T 28-03-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 714 0.0 T 28-03-2018 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 493 517 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Gene3D G3DSA:3.90.226.10 13 265 8.2E-53 T 28-03-2018 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 SUPERFAMILY SSF48179 495 609 1.87E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 SUPERFAMILY SSF52096 3 303 4.57E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Gene3D G3DSA:1.10.1040.10 503 592 2.3E-21 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Gene3D G3DSA:3.40.50.720 266 495 6.8E-60 T 28-03-2018 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 627 690 7.3E-6 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 496 592 1.1E-24 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 205 2.9E-37 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 SUPERFAMILY SSF48179 622 714 5.87E-23 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 316 494 9.2E-60 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 SUPERFAMILY SSF51735 314 495 4.77E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS18960 0d245e038db5ebd6c3a81a519381a80e 729 Gene3D G3DSA:1.10.1040.10 622 713 2.3E-15 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 214 1.7E-88 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 SMART SM00987 49 210 2.4E-40 T 28-03-2018 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 SMART SM00986 49 210 2.4E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 SUPERFAMILY SSF52141 5 220 2.01E-94 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 Pfam PF03167 Uracil DNA glycosylase superfamily 55 209 1.0E-27 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 4 221 40.006 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 Gene3D G3DSA:3.40.470.10 1 229 3.0E-104 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS00345 fa6d98ad5f83eef2ebecf35e0e7a91fe 229 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS09660 9d7df63c6ac7fc695d174d1cbe59162c 172 Gene3D G3DSA:3.10.129.10 1 172 6.8E-50 T 28-03-2018 WM46_RS09660 9d7df63c6ac7fc695d174d1cbe59162c 172 Pfam PF07977 FabA-like domain 29 158 1.2E-53 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS09660 9d7df63c6ac7fc695d174d1cbe59162c 172 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 4 172 2.4E-97 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS09660 9d7df63c6ac7fc695d174d1cbe59162c 172 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 2 172 51.668 T 28-03-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS09660 9d7df63c6ac7fc695d174d1cbe59162c 172 SUPERFAMILY SSF54637 3 169 1.94E-55 T 28-03-2018 IPR029069 HotDog domain WM46_RS19830 06f38afa72a39460aa51511270824236 337 SUPERFAMILY SSF74650 40 334 1.32E-6 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS19830 06f38afa72a39460aa51511270824236 337 Pfam PF14486 Domain of unknown function (DUF4432) 34 335 4.3E-15 T 28-03-2018 IPR027839 Protein of unknown function DUF4432 WM46_RS19830 06f38afa72a39460aa51511270824236 337 Gene3D G3DSA:2.70.98.10 21 337 4.8E-19 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 2 117 1.8E-51 T 28-03-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 Pfam PF03830 PTS system sorbose subfamily IIB component 163 310 1.7E-54 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 SUPERFAMILY SSF52728 161 320 4.05E-54 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 Pfam PF03610 PTS system fructose IIA component 5 116 2.5E-35 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 SUPERFAMILY SSF53062 3 128 1.44E-37 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 Gene3D G3DSA:3.40.50.510 2 136 2.2E-37 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 162 310 6.1E-55 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 WM46_RS04960 824628d310da969346a6fcda29bda1fd 322 Gene3D G3DSA:3.40.35.10 162 318 4.0E-59 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 SUPERFAMILY SSF56801 9 517 1.2E-131 T 28-03-2018 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Hamap MF_01524 Probable crotonobetaine/carnitine-CoA ligase [caiC]. 1 517 80.602 T 28-03-2018 IPR023456 Crotonobetaine/carnitine-CoA ligase CaiC GO:0009437|GO:0016878|GO:0051108|GO:0051109 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 435 510 2.4E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Gene3D G3DSA:2.30.38.10 335 419 1.4E-23 T 28-03-2018 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Gene3D G3DSA:3.40.50.980 5 184 3.4E-37 T 28-03-2018 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Gene3D G3DSA:3.40.50.980 185 334 6.6E-34 T 28-03-2018 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Pfam PF00501 AMP-binding enzyme 17 426 8.9E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS14645 b699c19cebe5b6c7c313d0dc206b8b86 517 Gene3D G3DSA:3.30.300.30 421 517 9.8E-21 T 28-03-2018 WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 SMART SM00091 111 177 1.5E-5 T 28-03-2018 IPR000014 PAS domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 SUPERFAMILY SSF141868 412 658 3.14E-81 T 28-03-2018 IPR001633 EAL domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 Pfam PF13426 PAS domain 123 225 2.1E-9 T 28-03-2018 IPR000014 PAS domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 Gene3D G3DSA:3.30.450.20 100 234 9.6E-20 T 28-03-2018 WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 SUPERFAMILY SSF55073 243 397 2.51E-46 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 Pfam PF00563 EAL domain 412 644 9.6E-64 T 28-03-2018 IPR001633 EAL domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 390 6.9E-47 T 28-03-2018 IPR000160 GGDEF domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 SUPERFAMILY SSF55785 123 234 3.49E-17 T 28-03-2018 IPR000014 PAS domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 Gene3D G3DSA:3.20.20.450 403 663 3.2E-88 T 28-03-2018 IPR001633 EAL domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 SMART SM00267 226 395 1.9E-70 T 28-03-2018 IPR000160 GGDEF domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 233 7.0E-16 T 28-03-2018 IPR000014 PAS domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 394 3.5E-37 T 28-03-2018 IPR000160 GGDEF domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 SMART SM00052 405 649 1.0E-117 T 28-03-2018 IPR001633 EAL domain WM46_RS05965 7957eecb9a6eeb4e1ad46b997b471b33 663 Gene3D G3DSA:3.30.70.270 235 402 1.2E-57 T 28-03-2018 WM46_RS05330 62329de8e83f6cd166a3f9c2e755e9cf 482 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 10 469 9.4E-151 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 WM46_RS05330 62329de8e83f6cd166a3f9c2e755e9cf 482 Pfam PF03553 Na+/H+ antiporter family 164 465 3.1E-42 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 WM46_RS06625 308f431f155119a98df2d5f4529f433c 172 Gene3D G3DSA:3.40.630.30 1 171 9.3E-34 T 28-03-2018 WM46_RS06625 308f431f155119a98df2d5f4529f433c 172 SUPERFAMILY SSF55729 3 165 2.92E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS06625 308f431f155119a98df2d5f4529f433c 172 Pfam PF00583 Acetyltransferase (GNAT) family 18 136 3.0E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 SUPERFAMILY SSF54111 1 99 2.88E-45 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 Pfam PF00547 Urease, gamma subunit 1 99 2.1E-46 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.804 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 7.0E-46 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 Gene3D G3DSA:3.30.280.10 2 99 6.4E-47 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 PIRSF PIRSF001223 1 100 4.2E-51 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16265 78bc227b3f499c8f4f3b5cce006e55c7 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.7E-50 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 SUPERFAMILY SSF47170 25 181 3.92E-52 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 Gene3D G3DSA:1.10.287.950 222 320 2.8E-14 T 28-03-2018 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 484 5.4E-61 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 191 211 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 60 75 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 1.7E-92 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 Gene3D G3DSA:1.10.287.950 321 520 6.4E-48 T 28-03-2018 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 Pfam PF00672 HAMP domain 217 265 1.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 SMART SM00283 269 516 3.4E-97 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 SMART SM00319 44 182 2.5E-70 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 SUPERFAMILY SSF58104 236 520 1.24E-76 T 28-03-2018 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 Pfam PF02203 Tar ligand binding domain homologue 1 176 5.4E-58 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 Gene3D G3DSA:1.20.120.30 23 190 2.3E-47 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain WM46_RS23915 d15e61bdf57afa81d9543119fafef0f1 554 SMART SM00304 216 268 6.2E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Pfam PF01926 50S ribosome-binding GTPase 205 322 2.0E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Pfam PF01926 50S ribosome-binding GTPase 5 119 1.4E-28 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 SUPERFAMILY SSF52540 4 163 1.9E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 SUPERFAMILY SSF52540 137 167 5.83E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 SUPERFAMILY SSF52540 200 464 5.83E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 202 368 9.6E-23 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 3.3E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Gene3D G3DSA:1.20.120.430 269 380 1.1E-17 T 28-03-2018 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Gene3D G3DSA:1.20.120.430 67 268 6.3E-48 T 28-03-2018 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 PIRSF PIRSF006485 1 466 9.4E-180 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Gene3D G3DSA:1.20.120.430 2 66 1.6E-15 T 28-03-2018 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Gene3D G3DSA:3.30.300.20 381 459 3.5E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 378 458 8.0E-27 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 Hamap MF_00195 GTPase Der [der]. 2 461 39.503 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.1E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 9.1E-10 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS00725 bbdcdcc88ac5d70f6d705e8ad574b7af 490 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 458 9.9E-180 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 WM46_RS23190 a5370a6795efa53bf16116f52abdadd7 128 PIRSF PIRSF000029 1 128 5.8E-60 T 28-03-2018 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 WM46_RS23190 a5370a6795efa53bf16116f52abdadd7 128 Gene3D G3DSA:1.20.120.10 24 128 9.7E-21 T 28-03-2018 WM46_RS23190 a5370a6795efa53bf16116f52abdadd7 128 SUPERFAMILY SSF47175 24 128 4.51E-34 T 28-03-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 WM46_RS23190 a5370a6795efa53bf16116f52abdadd7 128 Pfam PF07361 Cytochrome b562 24 128 2.2E-31 T 28-03-2018 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Gene3D G3DSA:1.10.1040.10 210 487 1.2E-88 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 1.4E-58 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 22 485 38.957 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 WM46_RS19310 45468652a008705ffa0af01060d58637 491 SUPERFAMILY SSF48179 210 368 1.11E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS19310 45468652a008705ffa0af01060d58637 491 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 368 6.5E-137 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 WM46_RS19310 45468652a008705ffa0af01060d58637 491 SUPERFAMILY SSF48179 349 484 6.29E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 342 1.4E-28 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 357 482 4.6E-23 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Gene3D G3DSA:3.40.50.720 56 208 6.5E-52 T 28-03-2018 WM46_RS19310 45468652a008705ffa0af01060d58637 491 Gene3D G3DSA:3.40.50.720 1 42 7.3E-5 T 28-03-2018 WM46_RS19310 45468652a008705ffa0af01060d58637 491 SUPERFAMILY SSF51735 30 209 6.06E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 SUPERFAMILY SSF52374 5 330 8.63E-99 T 28-03-2018 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 Pfam PF00579 tRNA synthetases class I (W and Y) 3 285 3.2E-89 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 142 163 3.1E-30 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 3.1E-30 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 3.1E-30 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 3.1E-30 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 331 42.546 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 Gene3D G3DSA:1.10.240.10 191 313 1.7E-32 T 28-03-2018 WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 Gene3D G3DSA:3.40.50.620 1 190 8.2E-75 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS17750 8e213a46c04cfbceff1081ef3db6c402 334 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 330 2.8E-117 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 SUPERFAMILY SSF54211 1 181 5.57E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 1.4E-24 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 Gene3D G3DSA:3.30.230.70 1 238 1.1E-61 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 5.0E-12 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 2.1E-114 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 SUPERFAMILY SSF55666 153 237 2.88E-26 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 49.762 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 WM46_RS20115 fb75d6789164dbc438a62457eb32f0e9 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 Gene3D G3DSA:3.30.70.20 100 136 4.2E-5 T 28-03-2018 WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 SUPERFAMILY SSF54862 57 178 1.4E-15 T 28-03-2018 WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 Gene3D G3DSA:3.30.70.20 137 178 2.0E-8 T 28-03-2018 WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 Pfam PF12838 4Fe-4S dicluster domain 60 107 1.6E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 Gene3D G3DSA:3.30.70.20 18 71 2.2E-5 T 28-03-2018 WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 Gene3D G3DSA:3.30.70.20 72 99 1.2E-12 T 28-03-2018 WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 93 104 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 Pfam PF00037 4Fe-4S binding domain 153 175 5.0E-5 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS22035 2857ded64078ec3ab5ae29325cd6ec53 178 TIGRFAM TIGR00402 napF: ferredoxin-type protein NapF 19 175 1.3E-31 T 28-03-2018 IPR004496 Ferredoxin-type protein NapF GO:0005506|GO:0009055|GO:0055114 WM46_RS23135 0225c1da612f26baec3f2881ccbe0b2e 114 Gene3D G3DSA:3.10.490.10 1 112 2.3E-29 T 28-03-2018 WM46_RS23135 0225c1da612f26baec3f2881ccbe0b2e 114 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 109 1.1E-24 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like WM46_RS23135 0225c1da612f26baec3f2881ccbe0b2e 114 SUPERFAMILY SSF110857 1 111 3.01E-34 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 38.951 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 304 8.4E-103 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 Pfam PF12706 Beta-lactamase superfamily domain 202 270 5.5E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 Pfam PF12706 Beta-lactamase superfamily domain 36 154 6.7E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 TIGRFAM TIGR02649 true_RNase_BN: ribonuclease BN 2 305 2.4E-187 T 28-03-2018 IPR013469 Ribonuclease BN GO:0016891|GO:0042779 WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 Gene3D G3DSA:3.60.15.10 1 305 1.8E-57 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS01830 1e362c342721a1d679428b9c1e3efea8 305 SUPERFAMILY SSF56281 1 304 7.73E-85 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS07070 f0040ac31a8958a060f2e969c8e9a0e3 220 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 213 3.6E-36 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 WM46_RS07070 f0040ac31a8958a060f2e969c8e9a0e3 220 Pfam PF01914 MarC family integral membrane protein 5 217 2.2E-69 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 WM46_RS07515 8d79c1af3188a28710a690790e48ee48 78 Pfam PF07869 Protein of unknown function (DUF1656) 19 69 4.4E-14 T 28-03-2018 IPR012451 Protein of unknown function DUF1656 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 SMART SM00342 194 277 1.9E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 261 277 4.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 246 261 4.2E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 Gene3D G3DSA:1.10.10.60 230 291 1.6E-12 T 28-03-2018 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 Gene3D G3DSA:1.10.10.60 176 229 7.2E-12 T 28-03-2018 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 Pfam PF02311 AraC-like ligand binding domain 26 160 6.4E-26 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 Gene3D G3DSA:2.60.120.280 7 170 3.0E-26 T 28-03-2018 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 231 273 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 SUPERFAMILY SSF51215 8 163 3.79E-38 T 28-03-2018 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 SUPERFAMILY SSF46689 231 279 2.2E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 SUPERFAMILY SSF46689 176 227 7.26E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS14510 a14a3f22787e659703a756e8e22b0ad7 292 Pfam PF12833 Helix-turn-helix domain 200 278 5.4E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS03640 02bc74e9cb4aa67f6b363d79b76ca821 355 Pfam PF02277 Phosphoribosyltransferase 11 344 7.3E-117 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03640 02bc74e9cb4aa67f6b363d79b76ca821 355 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 348 33.256 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03640 02bc74e9cb4aa67f6b363d79b76ca821 355 Gene3D G3DSA:1.10.1610.10 5 72 5.0E-28 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03640 02bc74e9cb4aa67f6b363d79b76ca821 355 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 15 345 5.6E-115 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS03640 02bc74e9cb4aa67f6b363d79b76ca821 355 Gene3D G3DSA:3.40.50.10210 73 329 1.7E-90 T 28-03-2018 WM46_RS03640 02bc74e9cb4aa67f6b363d79b76ca821 355 SUPERFAMILY SSF52733 6 343 2.35E-111 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 Gene3D G3DSA:3.40.190.10 83 171 3.8E-19 T 28-03-2018 WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.4E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 SUPERFAMILY SSF53850 85 285 1.09E-37 T 28-03-2018 WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 Pfam PF03466 LysR substrate binding domain 85 285 6.3E-45 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 Gene3D G3DSA:1.10.10.10 1 82 5.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 SUPERFAMILY SSF46785 1 109 6.46E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07060 6d291f9dc29328e75ad37e50262943c5 286 Gene3D G3DSA:3.40.190.10 172 260 1.7E-15 T 28-03-2018 WM46_RS08360 249963f73798775deb7726beae6b3886 644 Pfam PF08298 PrkA AAA domain 20 380 6.6E-179 T 28-03-2018 IPR013153 PrkA AAA domain WM46_RS08360 249963f73798775deb7726beae6b3886 644 SUPERFAMILY SSF52540 75 145 3.21E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08360 249963f73798775deb7726beae6b3886 644 SUPERFAMILY SSF52540 241 368 3.21E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08360 249963f73798775deb7726beae6b3886 644 PIRSF PIRSF000549 1 644 5.3E-292 T 28-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 WM46_RS08360 249963f73798775deb7726beae6b3886 644 SMART SM00763 19 380 1.7E-217 T 28-03-2018 IPR013153 PrkA AAA domain WM46_RS08360 249963f73798775deb7726beae6b3886 644 Pfam PF06798 PrkA serine protein kinase C-terminal domain 383 636 2.6E-75 T 28-03-2018 IPR010650 PrkA C-terminal domain WM46_RS08360 249963f73798775deb7726beae6b3886 644 Gene3D G3DSA:3.40.50.300 62 355 1.2E-13 T 28-03-2018 WM46_RS04535 0b74cdc1b8f941311948958364d41fbc 98 Pfam PF08972 Domain of unknown function (DUF1902) 12 49 8.6E-5 T 28-03-2018 IPR015066 Domain of unknown function DUF1902 WM46_RS04535 0b74cdc1b8f941311948958364d41fbc 98 SUPERFAMILY SSF143100 9 49 1.31E-5 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like WM46_RS04535 0b74cdc1b8f941311948958364d41fbc 98 Gene3D G3DSA:3.30.2390.10 5 67 7.5E-7 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 Gene3D G3DSA:1.10.10.10 1 85 1.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 SUPERFAMILY SSF53850 90 296 4.48E-44 T 28-03-2018 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 Gene3D G3DSA:3.40.190.10 182 266 4.0E-19 T 28-03-2018 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 Gene3D G3DSA:3.40.190.10 90 181 4.4E-26 T 28-03-2018 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 SUPERFAMILY SSF46785 3 113 1.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.4E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01170 62e9c41f93420eef6f36b1ffc885f256 308 Pfam PF03466 LysR substrate binding domain 90 292 5.6E-46 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Pfam PF13184 NusA-like KH domain 230 297 1.6E-27 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SUPERFAMILY SSF47794 429 492 5.02E-18 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SUPERFAMILY SSF47794 355 415 5.02E-17 T 28-03-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Gene3D G3DSA:3.30.1480.10 1 128 3.2E-45 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SUPERFAMILY SSF69705 1 126 2.75E-41 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Gene3D G3DSA:3.30.300.20 278 347 1.9E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Gene3D G3DSA:1.10.150.20 352 421 2.9E-15 T 28-03-2018 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Gene3D G3DSA:1.10.150.20 427 495 3.3E-17 T 28-03-2018 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 410 29.239 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Pfam PF14520 Helix-hairpin-helix domain 432 486 7.2E-9 T 28-03-2018 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SUPERFAMILY SSF50249 132 199 3.76E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Pfam PF08529 NusA N-terminal domain 4 123 7.1E-37 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SUPERFAMILY SSF54814 279 343 3.18E-15 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 440 489 3.6E-19 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 365 414 1.7E-20 T 28-03-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SUPERFAMILY SSF54814 201 278 3.73E-29 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 SMART SM00316 133 200 4.9E-8 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 342 9.6E-131 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Gene3D G3DSA:2.40.50.140 129 198 5.2E-13 T 28-03-2018 WM46_RS16775 cb4f47edc268abba72b1658a8e1a48b2 495 Gene3D G3DSA:3.30.300.20 199 276 6.2E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 Gene3D G3DSA:3.40.50.1000 32 207 4.2E-22 T 28-03-2018 IPR023214 HAD-like domain WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 3.9E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 3.9E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 3.9E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 3.9E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 13 191 1.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 190 9.1E-9 T 28-03-2018 IPR023214 HAD-like domain WM46_RS17830 4a61e9a887a7a50ffe78d44589b33381 222 SUPERFAMILY SSF56784 6 217 5.19E-46 T 28-03-2018 IPR023214 HAD-like domain WM46_RS02125 6e6635e8c63c245c2af8fd822685c061 165 Pfam PF03974 Ecotin 33 155 3.0E-53 T 28-03-2018 IPR023189 Proteinase inhibitor I11, ecotin domain WM46_RS02125 6e6635e8c63c245c2af8fd822685c061 165 PIRSF PIRSF006865 1 165 2.8E-68 T 28-03-2018 IPR005658 Proteinase inhibitor I11, ecotin WM46_RS02125 6e6635e8c63c245c2af8fd822685c061 165 Hamap MF_00706 Ecotin [eco]. 1 165 41.661 T 28-03-2018 IPR023084 Proteinase inhibitor I11, ecotin, gammaproteobacteria WM46_RS02125 6e6635e8c63c245c2af8fd822685c061 165 Gene3D G3DSA:2.60.40.550 30 102 4.5E-37 T 28-03-2018 WM46_RS02125 6e6635e8c63c245c2af8fd822685c061 165 Gene3D G3DSA:4.10.1230.10 108 162 1.0E-27 T 28-03-2018 IPR027438 Ecotin, C-terminal WM46_RS02125 6e6635e8c63c245c2af8fd822685c061 165 SUPERFAMILY SSF49772 29 163 2.88E-57 T 28-03-2018 IPR023189 Proteinase inhibitor I11, ecotin domain WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 Gene3D G3DSA:3.40.190.10 81 173 5.0E-16 T 28-03-2018 WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 Pfam PF03466 LysR substrate binding domain 90 294 2.6E-37 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 SUPERFAMILY SSF46785 6 112 2.46E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.3E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 Gene3D G3DSA:3.40.190.10 174 264 7.0E-19 T 28-03-2018 WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 SUPERFAMILY SSF53850 91 296 2.79E-40 T 28-03-2018 WM46_RS05450 79d707ab9cf3553b8f28230f2f5b7e5e 298 Gene3D G3DSA:1.10.10.10 3 80 7.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 2 552 6.8E-270 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 Gene3D G3DSA:3.30.420.40 1 273 1.0E-37 T 28-03-2018 WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 SUPERFAMILY SSF53067 5 284 1.42E-20 T 28-03-2018 WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 Hamap MF_00520 Ribulokinase [araB]. 1 558 59.666 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 Gene3D G3DSA:3.30.420.40 274 550 4.8E-50 T 28-03-2018 WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 291 501 3.1E-36 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS14515 ddf5700d881072b1415ef5afd6be30bf 569 SUPERFAMILY SSF53067 285 543 2.03E-42 T 28-03-2018 WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 Pfam PF00512 His Kinase A (phospho-acceptor) domain 147 202 7.1E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 4.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 4.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 357 2.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 SMART SM00388 145 205 4.4E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 Gene3D G3DSA:3.30.565.10 212 361 1.6E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 SUPERFAMILY SSF55874 195 359 7.73E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 Gene3D G3DSA:1.10.287.130 131 201 1.0E-7 T 28-03-2018 WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 SMART SM00387 252 361 2.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21935 6e53f498e12de6d2ae6abb01709086de 361 SUPERFAMILY SSF47384 129 202 1.49E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 SUPERFAMILY SSF52518 1 172 3.33E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS19345 31efb26695b15026b74434a8ec122373 548 Gene3D G3DSA:3.40.50.970 334 534 1.1E-49 T 28-03-2018 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 Gene3D G3DSA:3.40.50.970 1 184 2.5E-61 T 28-03-2018 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 374 522 1.4E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 SUPERFAMILY SSF52518 357 546 8.58E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS19345 31efb26695b15026b74434a8ec122373 548 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 545 9.1E-219 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 SUPERFAMILY SSF52467 183 341 5.51E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS19345 31efb26695b15026b74434a8ec122373 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 321 1.6E-42 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 Gene3D G3DSA:3.40.50.1220 185 333 1.8E-49 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS19345 31efb26695b15026b74434a8ec122373 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 165 3.4E-56 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM46_RS19345 31efb26695b15026b74434a8ec122373 548 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 411 430 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 12 358 55.139 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 Gene3D G3DSA:3.40.640.10 70 247 1.0E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 14 355 1.1E-125 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 Gene3D G3DSA:3.90.1150.10 248 357 7.7E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 SUPERFAMILY SSF53383 11 355 4.52E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 Gene3D G3DSA:3.90.1150.10 8 69 3.5E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS03030 f9b382e6a97b074e51f0a97476257de2 359 Pfam PF00155 Aminotransferase class I and II 49 354 2.5E-67 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 Gene3D G3DSA:2.160.10.10 1 196 1.7E-46 T 28-03-2018 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 Gene3D G3DSA:1.20.1180.10 197 262 1.0E-23 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 153 181 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 261 2.3E-29 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 20 48 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 260 2.7E-113 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 262 49.091 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 18 52 5.1E-8 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 2.1E-9 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 PIRSF PIRSF000456 5 262 1.2E-108 T 28-03-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 WM46_RS13915 02e2a2be8694ea3d388ebcace444ca7f 262 SUPERFAMILY SSF51161 2 262 1.32E-81 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 SUPERFAMILY SSF46689 264 314 3.65E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 Pfam PF12833 Helix-turn-helix domain 233 311 2.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 Pfam PF01965 DJ-1/PfpI family 5 171 3.9E-12 T 28-03-2018 IPR002818 DJ-1/PfpI WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 SUPERFAMILY SSF52317 3 192 2.62E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 Gene3D G3DSA:1.10.10.60 210 264 1.6E-12 T 28-03-2018 WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 SUPERFAMILY SSF46689 210 261 5.56E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 Gene3D G3DSA:3.40.50.880 1 209 1.3E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 Gene3D G3DSA:1.10.10.60 265 315 9.0E-11 T 28-03-2018 WM46_RS13135 6354a3976c094ed25077868e27c0ff16 318 SMART SM00342 227 310 1.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS03015 f83395077214217ebf1ecab8ad320a8b 245 Pfam PF00977 Histidine biosynthesis protein 1 234 1.4E-75 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 WM46_RS03015 f83395077214217ebf1ecab8ad320a8b 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 35.551 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 WM46_RS03015 f83395077214217ebf1ecab8ad320a8b 245 Gene3D G3DSA:3.20.20.70 1 245 8.4E-53 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS03015 f83395077214217ebf1ecab8ad320a8b 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 238 2.0E-79 T 28-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 WM46_RS03015 f83395077214217ebf1ecab8ad320a8b 245 SUPERFAMILY SSF51366 1 244 1.82E-65 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS02920 0a9e2de4c723cd8832099aeef53d2a50 228 SUPERFAMILY SSF56655 22 197 3.01E-29 T 28-03-2018 WM46_RS02920 0a9e2de4c723cd8832099aeef53d2a50 228 PRINTS PR00377 Inositol monophosphatase superfamily signature 31 51 1.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS02920 0a9e2de4c723cd8832099aeef53d2a50 228 PRINTS PR00377 Inositol monophosphatase superfamily signature 77 93 1.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS02920 0a9e2de4c723cd8832099aeef53d2a50 228 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 69 1.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS02920 0a9e2de4c723cd8832099aeef53d2a50 228 Gene3D G3DSA:3.30.540.10 3 185 2.7E-21 T 28-03-2018 WM46_RS02920 0a9e2de4c723cd8832099aeef53d2a50 228 Pfam PF00459 Inositol monophosphatase family 5 123 1.4E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 Gene3D G3DSA:3.40.50.740 109 195 1.4E-13 T 28-03-2018 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 SMART SM00926 43 104 9.2E-22 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 103 3.6E-19 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 SUPERFAMILY SSF53706 36 195 7.85E-56 T 28-03-2018 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 Pfam PF00384 Molybdopterin oxidoreductase 107 141 3.6E-6 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06780 9e8d4a09f59cb9bea3bd1417787d3436 195 Gene3D G3DSA:2.20.25.90 37 108 6.7E-20 T 28-03-2018 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 29 446 1.6E-140 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 SUPERFAMILY SSF53244 313 446 2.98E-37 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Gene3D G3DSA:3.40.1190.10 90 309 1.0E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 389 8.1E-15 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Gene3D G3DSA:3.40.1390.10 1 89 2.0E-27 T 28-03-2018 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Pfam PF08245 Mur ligase middle domain 106 292 3.6E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 SUPERFAMILY SSF63418 1 96 1.14E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Pfam PF01225 Mur ligase family, catalytic domain 26 92 9.8E-10 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 SUPERFAMILY SSF53623 100 310 4.06E-60 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 447 34.47 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14400 64fe4770a2ad30b3278dc2eafbede7ae 452 Gene3D G3DSA:3.90.190.20 312 452 1.6E-39 T 28-03-2018 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 Gene3D G3DSA:3.40.50.1360 82 257 2.7E-33 T 28-03-2018 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 SUPERFAMILY SSF100950 92 250 1.36E-29 T 28-03-2018 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 7.5E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 SMART SM00420 6 58 3.7E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 Pfam PF00455 DeoR C terminal sensor domain 92 249 4.5E-50 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 SMART SM01134 90 250 6.3E-62 T 28-03-2018 WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 Gene3D G3DSA:1.10.10.10 1 59 3.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21015 dcf30b43d44e71ad50030910e0c3df19 269 SUPERFAMILY SSF46785 5 60 2.77E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 549 21.405 T 28-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 Pfam PF03063 Prismane/CO dehydrogenase family 1 545 4.8E-155 T 28-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 Gene3D G3DSA:3.40.50.2030 235 375 2.0E-63 T 28-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 548 3.9E-231 T 28-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 Gene3D G3DSA:1.20.1270.20 1 147 1.7E-35 T 28-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 PIRSF PIRSF000076 1 550 2.6E-239 T 28-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 SUPERFAMILY SSF56821 1 548 3.92E-189 T 28-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 Gene3D G3DSA:1.20.1270.20 150 232 6.1E-21 T 28-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS10060 fe7b4af40d636230d8c595ecfad13eb7 550 Gene3D G3DSA:3.40.50.2030 376 550 5.0E-59 T 28-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 195 1.7E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 221 4.0E-73 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 SUPERFAMILY SSF56784 3 222 6.09E-48 T 28-03-2018 IPR023214 HAD-like domain WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 189 3.3E-17 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 78 194 4.2E-21 T 28-03-2018 IPR023214 HAD-like domain WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 Gene3D G3DSA:1.10.150.240 15 85 1.6E-18 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS24055 76219065a00075ea0a582b5bfa91be8b 225 Gene3D G3DSA:3.40.50.1000 86 225 2.0E-34 T 28-03-2018 IPR023214 HAD-like domain WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 Pfam PF02796 Helix-turn-helix domain of resolvase 144 188 8.9E-15 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 Pfam PF00239 Resolvase, N terminal domain 3 141 8.0E-34 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 ProSitePatterns PS00398 Site-specific recombinases signature 2. 60 72 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 Gene3D G3DSA:3.40.50.1390 1 112 2.7E-24 T 28-03-2018 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 Gene3D G3DSA:1.20.5.40 113 140 7.7E-10 T 28-03-2018 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 SUPERFAMILY SSF46689 144 186 3.4E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 Gene3D G3DSA:1.10.10.60 144 188 9.6E-10 T 28-03-2018 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 SUPERFAMILY SSF53041 1 141 3.01E-33 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS25880 5a29f5141771ff7c280b80b06d128ad6 189 SMART SM00857 2 142 4.1E-42 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS10110 b09f849028c5af5c8dcbda346f4007ed 242 PIRSF PIRSF039085 1 242 7.9E-85 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS10110 b09f849028c5af5c8dcbda346f4007ed 242 Gene3D G3DSA:3.40.50.300 1 242 1.8E-66 T 28-03-2018 WM46_RS10110 b09f849028c5af5c8dcbda346f4007ed 242 SUPERFAMILY SSF52540 3 232 3.17E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10110 b09f849028c5af5c8dcbda346f4007ed 242 SMART SM00382 27 218 4.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10110 b09f849028c5af5c8dcbda346f4007ed 242 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10110 b09f849028c5af5c8dcbda346f4007ed 242 Pfam PF00005 ABC transporter 20 170 4.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 Pfam PF17154 Gammaproteobacterial periplasmic sensor domain 36 155 3.2E-50 T 28-03-2018 IPR033419 Gammaproteobacterial periplasmic sensor domain GAPES3 WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 Pfam PF00563 EAL domain 415 647 1.4E-63 T 28-03-2018 IPR001633 EAL domain WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 Gene3D G3DSA:3.30.70.270 241 405 2.2E-21 T 28-03-2018 WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 SUPERFAMILY SSF141868 413 660 3.27E-75 T 28-03-2018 IPR001633 EAL domain WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 SMART SM00267 231 398 1.9E-31 T 28-03-2018 IPR000160 GGDEF domain WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 SUPERFAMILY SSF55073 249 400 3.92E-17 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 Gene3D G3DSA:3.20.20.450 406 657 5.9E-85 T 28-03-2018 IPR001633 EAL domain WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 Pfam PF00990 Diguanylate cyclase, GGDEF domain 247 394 3.6E-10 T 28-03-2018 IPR000160 GGDEF domain WM46_RS20680 156c4a08860eb4b242b42ed1f511208f 662 SMART SM00052 408 653 2.0E-112 T 28-03-2018 IPR001633 EAL domain WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 Gene3D G3DSA:3.40.50.20 104 201 3.1E-6 T 28-03-2018 WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 Pfam PF02625 XdhC and CoxI family 12 73 2.1E-17 T 28-03-2018 IPR003777 XdhC- CoxI WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 Gene3D G3DSA:3.40.50.20 258 393 1.5E-4 T 28-03-2018 WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 TIGRFAM TIGR03309 matur_yqeB: selenium-dependent molybdenum hydroxylase system protein, YqeB family 271 526 1.7E-122 T 28-03-2018 IPR017695 Selenium-dependent molybdenum hydroxylase system protein, YqeB family WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 Pfam PF13478 XdhC Rossmann domain 106 247 2.7E-31 T 28-03-2018 IPR027051 XdhC Rossmann domain WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 SUPERFAMILY SSF53187 406 489 4.77E-5 T 28-03-2018 WM46_RS24340 560f84bdc1f8c9ce3784bae2c262355a 541 Gene3D G3DSA:2.40.50.100 428 497 3.1E-4 T 28-03-2018 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 360 368 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 404 421 3.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 3.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 440 3.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 383 394 3.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 PRINTS PR00131 Glycosyl hydrolase family 1 signature 360 368 3.0E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 SUPERFAMILY SSF51445 1 460 5.05E-160 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 Gene3D G3DSA:3.20.20.80 3 459 1.7E-145 T 28-03-2018 WM46_RS19895 bf2f650e08840ba2434b848b05484b27 460 Pfam PF00232 Glycosyl hydrolase family 1 3 458 2.0E-133 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS09765 cf984141e00e4b2f64081c1c64f4b83d 215 Gene3D G3DSA:3.60.15.10 1 213 1.4E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09765 cf984141e00e4b2f64081c1c64f4b83d 215 Pfam PF00753 Metallo-beta-lactamase superfamily 10 192 1.4E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09765 cf984141e00e4b2f64081c1c64f4b83d 215 SMART SM00849 12 192 1.3E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09765 cf984141e00e4b2f64081c1c64f4b83d 215 SUPERFAMILY SSF56281 2 209 7.58E-62 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS10455 68d24380ac1aba8a7fa9fede1c4491ff 322 Gene3D G3DSA:1.20.970.10 1 71 1.6E-15 T 28-03-2018 WM46_RS10455 68d24380ac1aba8a7fa9fede1c4491ff 322 SUPERFAMILY SSF52418 79 320 1.16E-49 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS10455 68d24380ac1aba8a7fa9fede1c4491ff 322 Gene3D G3DSA:3.40.1030.10 80 322 3.1E-42 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS10455 68d24380ac1aba8a7fa9fede1c4491ff 322 Pfam PF00591 Glycosyl transferase family, a/b domain 95 320 2.5E-5 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS10455 68d24380ac1aba8a7fa9fede1c4491ff 322 SUPERFAMILY SSF47648 7 72 2.22E-14 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS10455 68d24380ac1aba8a7fa9fede1c4491ff 322 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 70 1.9E-10 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS07895 12eed2abfeaeed29ca172595f5f77ca3 407 SUPERFAMILY SSF103473 7 393 6.41E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07895 12eed2abfeaeed29ca172595f5f77ca3 407 Gene3D G3DSA:1.20.1250.20 214 400 5.5E-16 T 28-03-2018 WM46_RS07895 12eed2abfeaeed29ca172595f5f77ca3 407 Gene3D G3DSA:1.20.1250.20 1 199 1.2E-23 T 28-03-2018 WM46_RS07895 12eed2abfeaeed29ca172595f5f77ca3 407 Pfam PF07690 Major Facilitator Superfamily 13 356 8.4E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07895 12eed2abfeaeed29ca172595f5f77ca3 407 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 Pfam PF12833 Helix-turn-helix domain 193 271 5.1E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 266 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 Gene3D G3DSA:1.10.10.60 168 227 4.9E-14 T 28-03-2018 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 SUPERFAMILY SSF46689 170 221 1.52E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 270 1.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 254 1.7E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 SUPERFAMILY SSF46689 223 272 1.03E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 Gene3D G3DSA:2.60.120.280 14 161 4.6E-15 T 28-03-2018 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 SUPERFAMILY SSF51215 16 157 1.2E-13 T 28-03-2018 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 Pfam PF02311 AraC-like ligand binding domain 18 140 2.3E-21 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 SMART SM00342 187 270 3.9E-33 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 Hamap MF_01534 HTH-type transcriptional activator RhaS [rhaS]. 1 273 55.647 T 28-03-2018 IPR023609 Transcription regulator HTH, RhaS GO:0003700|GO:0006355|GO:0019299 WM46_RS18560 4ad512086861ba00d01181a6b02d759f 278 Gene3D G3DSA:1.10.10.60 228 275 5.5E-14 T 28-03-2018 WM46_RS09815 39f8d8660a4195b9541a59a6728483f7 248 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 248 46.165 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 WM46_RS09815 39f8d8660a4195b9541a59a6728483f7 248 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 241 2.7E-136 T 28-03-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 WM46_RS09815 39f8d8660a4195b9541a59a6728483f7 248 SUPERFAMILY SSF53448 3 245 2.93E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS09815 39f8d8660a4195b9541a59a6728483f7 248 Pfam PF02348 Cytidylyltransferase 4 221 6.5E-73 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 WM46_RS09815 39f8d8660a4195b9541a59a6728483f7 248 Gene3D G3DSA:3.90.550.10 1 248 1.4E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS12860 94f29dedfe7d2d2d77a06c2830bbc544 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 8.0E-97 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS12860 94f29dedfe7d2d2d77a06c2830bbc544 286 PIRSF PIRSF001359 1 286 8.7E-105 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS12860 94f29dedfe7d2d2d77a06c2830bbc544 286 Gene3D G3DSA:3.20.20.70 1 286 5.3E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS12860 94f29dedfe7d2d2d77a06c2830bbc544 286 SUPERFAMILY SSF51569 3 285 1.47E-90 T 28-03-2018 WM46_RS12860 94f29dedfe7d2d2d77a06c2830bbc544 286 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 2 285 1.6E-109 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 WM46_RS12860 94f29dedfe7d2d2d77a06c2830bbc544 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 3 285 1.6E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 Gene3D G3DSA:3.90.780.10 376 605 1.3E-49 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 SUPERFAMILY SSF56300 19 354 7.23E-88 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 PRINTS PR01607 Apyrase family signature 243 266 1.8E-32 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 PRINTS PR01607 Apyrase family signature 22 40 1.8E-32 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 PRINTS PR01607 Apyrase family signature 530 549 1.8E-32 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 PRINTS PR01607 Apyrase family signature 283 303 1.8E-32 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 PRINTS PR01607 Apyrase family signature 215 232 1.8E-32 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 PRINTS PR01607 Apyrase family signature 428 451 1.8E-32 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 TIGRFAM TIGR01390 CycNucDiestase: 2',3'-cyclic-nucleotide 2'-phosphodiesterase 22 647 0.0 T 28-03-2018 IPR006294 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase GO:0008663|GO:0009117 KEGG: 00230+3.1.4.16+3.1.3.6|KEGG: 00240+3.1.4.16+3.1.3.6 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 ProSitePatterns PS00786 5'-nucleotidase signature 2. 109 120 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 ProSitePatterns PS00785 5'-nucleotidase signature 1. 24 36 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 Pfam PF00149 Calcineurin-like phosphoesterase 24 259 2.8E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 Pfam PF02872 5'-nucleotidase, C-terminal domain 355 550 1.8E-22 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 SUPERFAMILY SSF55816 355 596 2.49E-39 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 WM46_RS23055 0ddf17267ff7312164e8e16ae0f1b8fb 647 Gene3D G3DSA:3.60.21.10 12 375 8.5E-84 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS03190 6c959c815fe1558f91c61310ac3fed7c 460 Gene3D G3DSA:3.40.50.300 158 443 1.6E-46 T 28-03-2018 WM46_RS03190 6c959c815fe1558f91c61310ac3fed7c 460 Pfam PF03796 DnaB-like helicase C terminal domain 179 422 6.5E-74 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 WM46_RS03190 6c959c815fe1558f91c61310ac3fed7c 460 SUPERFAMILY SSF52540 175 245 3.63E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03190 6c959c815fe1558f91c61310ac3fed7c 460 SUPERFAMILY SSF52540 288 422 3.63E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03190 6c959c815fe1558f91c61310ac3fed7c 460 Gene3D G3DSA:1.10.860.10 4 142 8.7E-7 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM46_RS03190 6c959c815fe1558f91c61310ac3fed7c 460 SUPERFAMILY SSF48024 7 105 2.48E-7 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS08575 1eb5692c858ee06431de8f037c01ae0c 85 Gene3D G3DSA:3.30.1660.10 21 85 2.8E-22 T 28-03-2018 IPR025543 Dodecin-like WM46_RS08575 1eb5692c858ee06431de8f037c01ae0c 85 SUPERFAMILY SSF159871 3 85 3.01E-25 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS08575 1eb5692c858ee06431de8f037c01ae0c 85 Pfam PF07338 Protein of unknown function (DUF1471) 34 85 1.1E-20 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 Pfam PF00083 Sugar (and other) transporter 250 384 8.3E-7 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 Gene3D G3DSA:1.20.1250.20 3 202 3.4E-35 T 28-03-2018 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 Pfam PF07690 Major Facilitator Superfamily 11 236 5.5E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 PRINTS PR01035 Tetracycline resistance protein signature 79 103 1.5E-10 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.5E-10 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 PRINTS PR01035 Tetracycline resistance protein signature 106 127 1.5E-10 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.5E-10 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 PRINTS PR01035 Tetracycline resistance protein signature 17 33 1.5E-10 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS12995 9c37911422c8964f5646414688f1be75 401 SUPERFAMILY SSF103473 6 397 8.46E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS12995 9c37911422c8964f5646414688f1be75 401 Gene3D G3DSA:1.20.1250.20 203 401 2.8E-26 T 28-03-2018 WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 30 48 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 281 3.5E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 TIGRFAM TIGR01138 cysM: cysteine synthase B 3 292 7.9E-166 T 28-03-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 SUPERFAMILY SSF53686 3 289 3.67E-94 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 Gene3D G3DSA:3.40.50.1100 20 129 1.5E-35 T 28-03-2018 WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 Gene3D G3DSA:3.40.50.1100 130 303 2.0E-46 T 28-03-2018 WM46_RS01095 5af8e3ae5a00fdce49eac14f59d41de7 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 5 292 1.3E-127 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 WM46_RS16270 56da35f612e201a328b52c920e2aad4f 106 Gene3D G3DSA:2.10.150.10 1 101 1.4E-45 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16270 56da35f612e201a328b52c920e2aad4f 106 SUPERFAMILY SSF51278 1 103 3.01E-46 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16270 56da35f612e201a328b52c920e2aad4f 106 Pfam PF00699 Urease beta subunit 3 99 2.1E-43 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16270 56da35f612e201a328b52c920e2aad4f 106 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 31.65 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS16270 56da35f612e201a328b52c920e2aad4f 106 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 101 3.5E-44 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 WM46_RS26135 a47e7568518d6227d24c732f328a36ac 234 Pfam PF13610 DDE domain 75 212 8.6E-49 T 28-03-2018 IPR032874 DDE domain WM46_RS26135 a47e7568518d6227d24c732f328a36ac 234 SUPERFAMILY SSF53098 75 191 3.29E-7 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS26135 a47e7568518d6227d24c732f328a36ac 234 Gene3D G3DSA:3.30.420.10 72 210 1.3E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS26135 a47e7568518d6227d24c732f328a36ac 234 Gene3D G3DSA:1.10.10.10 4 61 5.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11510 c0c550950998001032294cf610533014 268 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 75 82 - T 28-03-2018 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 Reactome: R-HSA-6798695 WM46_RS11510 c0c550950998001032294cf610533014 268 ProSitePatterns PS00531 Ribonuclease T2 family histidine active site 2. 148 159 - T 28-03-2018 IPR033130 Ribonuclease T2, His active site 2 Reactome: R-HSA-6798695 WM46_RS11510 c0c550950998001032294cf610533014 268 SUPERFAMILY SSF55895 33 261 6.54E-27 T 28-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 WM46_RS11510 c0c550950998001032294cf610533014 268 Gene3D G3DSA:3.90.730.10 30 267 9.3E-34 T 28-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 WM46_RS11510 c0c550950998001032294cf610533014 268 Pfam PF00445 Ribonuclease T2 family 38 237 3.1E-11 T 28-03-2018 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 Reactome: R-HSA-6798695 WM46_RS06365 7e4d2f87bfb04e2f333ef6edbb88ceca 175 SUPERFAMILY SSF81342 4 172 9.42E-27 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM46_RS06365 7e4d2f87bfb04e2f333ef6edbb88ceca 175 Pfam PF01292 Prokaryotic cytochrome b561 5 172 9.0E-21 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM46_RS06365 7e4d2f87bfb04e2f333ef6edbb88ceca 175 Gene3D G3DSA:1.20.950.20 2 175 3.5E-25 T 28-03-2018 WM46_RS18140 07c813b5c498a6326d12cea03d2d30d9 180 Pfam PF04011 LemA family 9 176 2.3E-55 T 28-03-2018 IPR007156 LemA WM46_RS18140 07c813b5c498a6326d12cea03d2d30d9 180 Gene3D G3DSA:1.20.1440.20 12 180 5.3E-53 T 28-03-2018 WM46_RS18140 07c813b5c498a6326d12cea03d2d30d9 180 SUPERFAMILY SSF140478 25 169 3.92E-46 T 28-03-2018 IPR023353 LemA-like domain WM46_RS11200 bbc43a2085576414247845cbeb1e4860 468 Pfam PF03573 outer membrane porin, OprD family 33 431 2.1E-24 T 28-03-2018 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 WM46_RS11200 bbc43a2085576414247845cbeb1e4860 468 Gene3D G3DSA:2.40.160.10 2 468 6.5E-96 T 28-03-2018 WM46_RS11200 bbc43a2085576414247845cbeb1e4860 468 SUPERFAMILY SSF56935 214 320 6.28E-5 T 28-03-2018 WM46_RS08855 38bdace7c242f815eb4fd0ff39ada64f 81 Pfam PF06183 DinI-like family 14 78 1.7E-28 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS08855 38bdace7c242f815eb4fd0ff39ada64f 81 SUPERFAMILY SSF54857 1 80 5.49E-29 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS08855 38bdace7c242f815eb4fd0ff39ada64f 81 Gene3D G3DSA:3.30.910.10 1 78 2.3E-33 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS09200 420285598df34ad59a326810b27019de 459 Pfam PF04945 YHS domain 408 454 3.1E-16 T 28-03-2018 IPR007029 YHS domain WM46_RS09200 420285598df34ad59a326810b27019de 459 Gene3D G3DSA:1.10.620.20 382 459 1.1E-7 T 28-03-2018 WM46_RS09200 420285598df34ad59a326810b27019de 459 Pfam PF10080 Predicted membrane protein (DUF2318) 298 400 2.9E-28 T 28-03-2018 IPR018758 Domain of unknown function DUF2318, membrane WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 Pfam PF00294 pfkB family carbohydrate kinase 12 296 5.2E-64 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 Gene3D G3DSA:2.20.150.10 11 45 1.2E-6 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 4 305 1.6E-95 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 Gene3D G3DSA:3.40.1190.20 46 309 4.6E-46 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 SUPERFAMILY SSF53613 4 297 4.99E-63 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS08070 4bdabe6edb857d53fa4ad0397405d938 310 PIRSF PIRSF000535 1 310 4.1E-110 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 WM46_RS01320 1f2ede060e68e887ada4986b62bd69f8 321 Gene3D G3DSA:3.40.367.20 110 299 8.3E-30 T 28-03-2018 WM46_RS01320 1f2ede060e68e887ada4986b62bd69f8 321 SUPERFAMILY SSF53067 4 318 2.48E-63 T 28-03-2018 WM46_RS01320 1f2ede060e68e887ada4986b62bd69f8 321 Gene3D G3DSA:3.30.420.40 1 109 9.1E-16 T 28-03-2018 WM46_RS01320 1f2ede060e68e887ada4986b62bd69f8 321 TIGRFAM TIGR00749 glk: glucokinase 6 310 3.8E-151 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 WM46_RS01320 1f2ede060e68e887ada4986b62bd69f8 321 Pfam PF02685 Glucokinase 6 315 1.3E-122 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 WM46_RS01320 1f2ede060e68e887ada4986b62bd69f8 321 Hamap MF_00524 Glucokinase [glk]. 4 316 35.676 T 28-03-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 WM46_RS00610 f8e66de7281ef093ba8e617478406dc8 243 PIRSF PIRSF004808 1 243 1.5E-79 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS00610 f8e66de7281ef093ba8e617478406dc8 243 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 241 9.8E-95 T 28-03-2018 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 WM46_RS00610 f8e66de7281ef093ba8e617478406dc8 243 Pfam PF00588 SpoU rRNA Methylase family 5 154 2.4E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM46_RS00610 f8e66de7281ef093ba8e617478406dc8 243 Gene3D G3DSA:3.40.1280.10 1 165 2.2E-44 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS00610 f8e66de7281ef093ba8e617478406dc8 243 SUPERFAMILY SSF75217 4 164 2.55E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 PRINTS PR00207 Flagellin signature 36 53 3.7E-30 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 PRINTS PR00207 Flagellin signature 75 94 3.7E-30 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 PRINTS PR00207 Flagellin signature 110 133 3.7E-30 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 Gene3D G3DSA:1.20.1330.10 215 397 3.7E-20 T 28-03-2018 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 Gene3D G3DSA:1.20.1330.10 39 214 1.0E-41 T 28-03-2018 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 Pfam PF00700 Bacterial flagellin C-terminal helical region 340 424 7.9E-29 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 SUPERFAMILY SSF64518 1 425 5.89E-94 T 28-03-2018 WM46_RS03880 eccfcebf8600db340a40c5c4cfff3169 425 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 139 1.4E-42 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 WM46_RS07265 8053db052823eb3feed36425c91fbade 406 Gene3D G3DSA:1.10.10.10 11 77 4.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07265 8053db052823eb3feed36425c91fbade 406 SUPERFAMILY SSF53067 87 391 7.56E-45 T 28-03-2018 WM46_RS07265 8053db052823eb3feed36425c91fbade 406 Gene3D G3DSA:3.30.420.40 206 395 3.2E-41 T 28-03-2018 WM46_RS07265 8053db052823eb3feed36425c91fbade 406 Pfam PF00480 ROK family 90 389 5.8E-53 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS07265 8053db052823eb3feed36425c91fbade 406 SUPERFAMILY SSF46785 12 77 1.44E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07265 8053db052823eb3feed36425c91fbade 406 Gene3D G3DSA:3.30.420.40 78 205 3.6E-16 T 28-03-2018 WM46_RS09275 bcf89298a00fb088a7d14ce2797038e3 435 Gene3D G3DSA:1.20.1250.20 226 435 4.1E-28 T 28-03-2018 WM46_RS09275 bcf89298a00fb088a7d14ce2797038e3 435 SUPERFAMILY SSF103473 11 433 1.05E-91 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS09275 bcf89298a00fb088a7d14ce2797038e3 435 PIRSF PIRSF002808 1 435 2.3E-36 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS09275 bcf89298a00fb088a7d14ce2797038e3 435 Gene3D G3DSA:1.20.1250.20 10 211 1.5E-45 T 28-03-2018 WM46_RS09275 bcf89298a00fb088a7d14ce2797038e3 435 Pfam PF07690 Major Facilitator Superfamily 25 392 3.9E-61 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 SUPERFAMILY SSF52540 240 485 2.51E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 SUPERFAMILY SSF52540 4 228 1.52E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 Pfam PF00005 ABC transporter 278 433 8.6E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 Pfam PF00005 ABC transporter 21 171 2.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 TIGRFAM TIGR02633 xylG: D-xylose ABC transporter, ATP-binding protein 4 502 2.5E-280 T 28-03-2018 IPR013455 ABC transporter, D-xylose, ATP-binding protein GO:0005524|GO:0015614|GO:0015753|GO:0016020 WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 Gene3D G3DSA:3.40.50.300 255 512 4.7E-40 T 28-03-2018 WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 SMART SM00382 29 219 5.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 SMART SM00382 286 482 2.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS20445 2fa521a45795aa51ca434590e879fef1 513 Gene3D G3DSA:3.40.50.300 1 234 3.1E-49 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 SUPERFAMILY SSF56801 883 1402 1.03E-124 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 SUPERFAMILY SSF52777 451 635 2.11E-15 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1021 1032 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 908 1302 1.1E-102 T 28-03-2018 IPR010071 Amino acid adenylation domain WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:3.40.50.980 881 1024 1.7E-34 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 SUPERFAMILY SSF52777 621 855 5.0E-15 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:1.10.1200.10 1380 1464 1.1E-4 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Pfam PF00501 AMP-binding enzyme 897 1278 1.2E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:2.30.38.10 1186 1268 4.3E-14 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 SUPERFAMILY SSF52777 4 172 3.67E-17 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Pfam PF00668 Condensation domain 473 709 9.4E-11 T 28-03-2018 IPR001242 Condensation domain WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Pfam PF00668 Condensation domain 3 423 6.4E-23 T 28-03-2018 IPR001242 Condensation domain WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 SUPERFAMILY SSF52777 185 435 1.78E-30 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:3.30.300.30 1274 1379 4.3E-23 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:3.30.559.10 428 635 4.1E-15 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:3.30.559.10 1 186 6.1E-18 T 28-03-2018 WM46_RS13320 e717b2e1df993df271130b6ea300ec27 1464 Gene3D G3DSA:3.40.50.980 1025 1179 2.9E-43 T 28-03-2018 WM46_RS08985 28c3ca0b7adb133a954397f832281dc0 245 SMART SM00481 4 78 1.4E-20 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal WM46_RS08985 28c3ca0b7adb133a954397f832281dc0 245 Hamap MF_01561 Probable phosphatase YcdX [ycdX]. 1 243 50.585 T 28-03-2018 IPR023710 Probable phosphatase YcdX GO:0008270 WM46_RS08985 28c3ca0b7adb133a954397f832281dc0 245 Pfam PF02811 PHP domain 5 81 1.7E-8 T 28-03-2018 IPR004013 PHP domain GO:0003824 WM46_RS08985 28c3ca0b7adb133a954397f832281dc0 245 Gene3D G3DSA:3.20.20.140 1 245 1.2E-38 T 28-03-2018 WM46_RS08985 28c3ca0b7adb133a954397f832281dc0 245 SUPERFAMILY SSF89550 3 241 7.06E-64 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM46_RS08590 0901da8a8229b75be750df0bf11d31bc 179 Pfam PF05433 Glycine zipper 2TM domain 73 113 8.5E-12 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 PIRSF PIRSF006276 1 144 2.7E-17 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 Pfam PF00582 Universal stress protein family 1 144 1.2E-29 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 SUPERFAMILY SSF52402 3 144 6.36E-31 T 28-03-2018 WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 PRINTS PR01438 Universal stress protein signature 105 117 7.8E-10 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 PRINTS PR01438 Universal stress protein signature 2 20 7.8E-10 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 PRINTS PR01438 Universal stress protein signature 122 144 7.8E-10 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS06255 b8872f1ae154d2a5a8a0ba31d5e384ba 144 Gene3D G3DSA:3.40.50.620 2 144 6.6E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 1.7E-43 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 29.129 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 4.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 4.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 4.1E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 Pfam PF01016 Ribosomal L27 protein 2 82 3.8E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 SUPERFAMILY SSF110324 2 82 2.06E-34 T 28-03-2018 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 2.0E-18 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16850 5c04fe49375f214615261c0f0a7d4010 85 Gene3D G3DSA:2.40.50.100 20 84 7.9E-31 T 28-03-2018 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 PRINTS PR00123 ATP synthase A subunit signature 104 120 3.2E-15 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 PRINTS PR00123 ATP synthase A subunit signature 203 225 3.2E-15 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 PRINTS PR00123 ATP synthase A subunit signature 251 266 3.2E-15 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 SUPERFAMILY SSF81336 95 265 1.57E-49 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 38 266 5.5E-43 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 Hamap MF_01393 ATP synthase subunit a [atpB]. 12 271 16.117 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 ProSitePatterns PS00449 ATP synthase a subunit signature. 206 215 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 Gene3D G3DSA:1.20.120.220 95 271 4.8E-54 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19495 daa7077fcd4674722324b974f43af257 271 Pfam PF00119 ATP synthase A chain 47 265 1.3E-55 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 Gene3D G3DSA:3.40.140.10 180 294 3.0E-17 T 28-03-2018 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 Gene3D G3DSA:3.40.140.10 28 171 4.5E-27 T 28-03-2018 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 TIGRFAM TIGR01355 cyt_deam_dimer: cytidine deaminase 31 284 6.4E-84 T 28-03-2018 IPR006263 Cytidine deaminase, homodimeric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 157 276 3.6E-43 T 28-03-2018 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 SUPERFAMILY SSF53927 152 293 5.35E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 Hamap MF_01558 Cytidine deaminase [cdd]. 1 292 49.565 T 28-03-2018 IPR020797 Cytidine deaminase, bacteria GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 PIRSF PIRSF006334 14 293 6.9E-104 T 28-03-2018 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 59 139 2.3E-11 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM46_RS02485 33138233dbac9b1693863e74bddef913 294 SUPERFAMILY SSF53927 1 148 2.88E-40 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS02485 33138233dbac9b1693863e74bddef913 294 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 102 136 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 SUPERFAMILY SSF103515 588 901 1.26E-52 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 Gene3D G3DSA:2.40.128.130 580 901 1.3E-53 T 28-03-2018 WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 SMART SM00869 622 890 3.9E-48 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 Pfam PF03212 Pertactin 414 536 1.5E-11 T 28-03-2018 IPR004899 Pertactin, central region WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 SUPERFAMILY SSF51126 111 537 1.51E-35 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 Pfam PF03797 Autotransporter beta-domain 625 879 2.7E-51 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 Gene3D G3DSA:2.160.20.20 11 541 9.8E-49 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS18765 513336be74dfb6dabd568a00c30534f1 901 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 435 901 9.6E-127 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 Pfam PF01842 ACT domain 4 68 3.3E-15 T 28-03-2018 IPR002912 ACT domain WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 Gene3D G3DSA:3.30.70.260 2 87 4.8E-24 T 28-03-2018 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 159 1.1E-68 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 Pfam PF10369 Small subunit of acetolactate synthase 84 158 5.4E-24 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 SUPERFAMILY SSF55021 79 162 1.2E-26 T 28-03-2018 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-36 T 28-03-2018 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 Gene3D G3DSA:3.30.70.1150 88 161 1.7E-25 T 28-03-2018 WM46_RS14435 7b597f35ebbd441c2237bdd548a0ba71 163 SUPERFAMILY SSF55021 2 74 1.89E-22 T 28-03-2018 WM46_RS23565 8338d4a8df7b36ee414713f9344eeb04 236 SUPERFAMILY SSF51735 6 224 2.14E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23565 8338d4a8df7b36ee414713f9344eeb04 236 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 67 222 2.5E-14 T 28-03-2018 WM46_RS23565 8338d4a8df7b36ee414713f9344eeb04 236 Gene3D G3DSA:3.40.50.720 39 223 2.1E-13 T 28-03-2018 WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 Pfam PF00772 DnaB-like helicase N terminal domain 13 110 9.9E-32 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 Gene3D G3DSA:1.10.860.10 2 151 7.3E-41 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 SUPERFAMILY SSF48024 13 118 2.62E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 13 445 1.9E-142 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 Gene3D G3DSA:3.40.50.300 167 450 1.8E-56 T 28-03-2018 WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 Pfam PF03796 DnaB-like helicase C terminal domain 185 443 2.5E-92 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 SUPERFAMILY SSF52540 183 255 2.53E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22180 39bf625e3247f806445f3dcbf6a1d732 452 SUPERFAMILY SSF52540 282 435 2.53E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 13 306 5.2E-97 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 SUPERFAMILY SSF53067 137 310 1.88E-47 T 28-03-2018 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 Gene3D G3DSA:3.30.420.40 1 124 2.1E-37 T 28-03-2018 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 PIRSF PIRSF001267 3 506 6.7E-207 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 Pfam PF02541 Ppx/GppA phosphatase family 26 308 1.3E-102 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 SUPERFAMILY SSF53067 13 133 4.24E-36 T 28-03-2018 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 Gene3D G3DSA:3.30.420.150 125 305 1.2E-34 T 28-03-2018 WM46_RS00760 40a27f7014d2e5806e9b591646d9870c 513 SUPERFAMILY SSF109604 313 506 9.42E-58 T 28-03-2018 WM46_RS08225 6819876d1244e82160a6939706ec7050 435 SUPERFAMILY SSF52821 288 428 5.5E-31 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 SMART SM00450 146 267 1.2E-17 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 SMART SM00450 27 139 1.4 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 SMART SM00450 294 422 6.1E-16 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 Gene3D G3DSA:3.40.250.10 284 434 9.3E-27 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 SUPERFAMILY SSF52821 145 321 7.46E-26 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 Pfam PF00581 Rhodanese-like domain 297 418 1.3E-11 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 Pfam PF00581 Rhodanese-like domain 177 263 1.2E-10 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 SUPERFAMILY SSF52821 35 126 1.1E-7 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 ProSitePatterns PS00380 Rhodanese signature 1. 181 192 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 WM46_RS08225 6819876d1244e82160a6939706ec7050 435 ProSitePatterns PS00683 Rhodanese C-terminal signature. 406 416 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 WM46_RS08225 6819876d1244e82160a6939706ec7050 435 Gene3D G3DSA:3.40.250.10 139 283 4.1E-26 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS08225 6819876d1244e82160a6939706ec7050 435 Gene3D G3DSA:3.40.250.10 21 132 5.0E-7 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS13020 b304a7615cf829e28e80951b8a70ce5c 364 Pfam PF07759 Protein of unknown function (DUF1615) 50 362 2.7E-148 T 28-03-2018 IPR011673 Protein of unknown function DUF1615 WM46_RS13020 b304a7615cf829e28e80951b8a70ce5c 364 ProDom PD041438 LIPOPROTEIN YAIW PRECURSOR SIGNAL MEMBRANE OUTER LIPOPROTEIN ECS0428 XAC0592 SECRETED 13 364 0.0 T 28-03-2018 IPR011673 Protein of unknown function DUF1615 WM46_RS04735 2397e28c263474c2ca99c8b8b326741e 81 Pfam PF08809 Phage related hypothetical protein (DUF1799) 2 76 1.8E-17 T 28-03-2018 IPR014915 Bacteriophage TLS, TfmB WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 319 3.6E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 Gene3D G3DSA:3.40.50.1220 190 338 2.7E-32 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 525 4.8E-40 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 170 7.3E-42 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 SUPERFAMILY SSF52518 357 557 9.58E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 Gene3D G3DSA:3.40.50.970 339 533 9.6E-42 T 28-03-2018 WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 SUPERFAMILY SSF52467 182 352 1.39E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 SUPERFAMILY SSF52518 2 176 1.81E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 WM46_RS10075 a1f120e29e2fdc4fc745fe02808d3440 572 Gene3D G3DSA:3.40.50.970 1 189 2.0E-43 T 28-03-2018 WM46_RS02475 a39116dd4ad8ca09aeece20bbd2437e3 79 ProDom PD058881 MEMBRANE TRANSMEMBRANE YEIS INNER 1 79 1.0E-9 T 28-03-2018 IPR020155 Uncharacterised protein family YeiS GO:0016021 WM46_RS02475 a39116dd4ad8ca09aeece20bbd2437e3 79 Pfam PF10808 Protein of unknown function (DUF2542) 1 78 1.3E-21 T 28-03-2018 IPR020155 Uncharacterised protein family YeiS GO:0016021 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 271 1.2E-102 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 Pfam PF00809 Pterin binding enzyme 18 257 3.7E-90 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 Gene3D G3DSA:3.20.20.20 155 276 5.0E-49 T 28-03-2018 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 Gene3D G3DSA:3.20.20.20 14 154 2.2E-59 T 28-03-2018 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS16810 9ce22e56a03e77e2ebe816479aa6c297 282 SUPERFAMILY SSF51717 6 274 8.37E-105 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 WM46_RS11930 462cf114dc2716b4af04dee9a6d15d93 378 Gene3D G3DSA:3.40.50.1820 36 377 5.8E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11930 462cf114dc2716b4af04dee9a6d15d93 378 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 67 249 9.3E-5 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 WM46_RS11930 462cf114dc2716b4af04dee9a6d15d93 378 SUPERFAMILY SSF53474 277 378 6.93E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11930 462cf114dc2716b4af04dee9a6d15d93 378 SUPERFAMILY SSF53474 15 199 6.93E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS22880 e1b193bdb51d401ba9ae111ceb4f05d8 316 SUPERFAMILY SSF52540 13 157 1.31E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22880 e1b193bdb51d401ba9ae111ceb4f05d8 316 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 12 300 1.7E-125 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 WM46_RS22880 e1b193bdb51d401ba9ae111ceb4f05d8 316 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 12 309 29.836 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 WM46_RS22880 e1b193bdb51d401ba9ae111ceb4f05d8 316 Gene3D G3DSA:3.40.50.300 9 203 1.2E-60 T 28-03-2018 WM46_RS22880 e1b193bdb51d401ba9ae111ceb4f05d8 316 Gene3D G3DSA:1.10.287.890 207 289 2.8E-25 T 28-03-2018 WM46_RS22880 e1b193bdb51d401ba9ae111ceb4f05d8 316 Pfam PF01715 IPP transferase 46 290 9.9E-86 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 SUPERFAMILY SSF63737 1 193 4.97E-46 T 28-03-2018 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 Gene3D G3DSA:1.25.50.10 547 870 2.7E-123 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 12 869 0.0 T 28-03-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 Pfam PF01433 Peptidase family M1 domain 208 439 7.8E-60 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 Gene3D G3DSA:1.10.390.10 280 443 4.3E-51 T 28-03-2018 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 258 268 1.1E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 176 191 1.1E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 313 325 1.1E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 294 309 1.1E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 126 141 1.1E-8 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 SUPERFAMILY SSF55486 204 450 7.33E-75 T 28-03-2018 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 Gene3D G3DSA:2.60.40.1730 15 194 6.3E-30 T 28-03-2018 WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 444 545 2.9E-33 T 28-03-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold WM46_RS09740 561b4cb33291e785d91d06bec68efcef 870 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 548 870 2.2E-119 T 28-03-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal WM46_RS25735 498dfabfbe2044bede8063af959549ca 325 Pfam PF08943 CsiD 21 314 7.8E-150 T 28-03-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 WM46_RS25735 498dfabfbe2044bede8063af959549ca 325 Gene3D G3DSA:3.60.130.10 15 325 5.6E-63 T 28-03-2018 WM46_RS25735 498dfabfbe2044bede8063af959549ca 325 ProDom PD135861 METAL-BINDING IRON CSID GAB CYTOPLASMIC 3D-STRUCTURE HOMOLOG DIRECT SEQUENCING 19 314 2.0E-144 T 28-03-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 WM46_RS25735 498dfabfbe2044bede8063af959549ca 325 Hamap MF_01083 Protein CsiD [csiD]. 1 325 73.869 T 28-03-2018 IPR015038 Uncharacterised protein family CsiD GO:0005506 WM46_RS25735 498dfabfbe2044bede8063af959549ca 325 SUPERFAMILY SSF51197 20 322 2.06E-91 T 28-03-2018 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 Pfam PF10415 Fumarase C C-terminus 408 461 4.1E-25 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 Gene3D G3DSA:1.20.200.10 139 417 2.1E-88 T 28-03-2018 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 461 1.8E-251 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 SUPERFAMILY SSF48557 5 459 1.57E-156 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 462 91.695 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 Gene3D G3DSA:1.10.275.10 2 138 1.1E-59 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 3.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 3.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 3.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 3.6E-34 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 Pfam PF00206 Lyase 12 342 8.1E-122 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS07375 8d7414b95ea35d412acf6a2558852d3a 467 Gene3D G3DSA:1.10.40.30 418 462 1.8E-25 T 28-03-2018 WM46_RS25705 5a6ea4309e20866bda11947b99368624 149 Gene3D G3DSA:3.10.350.10 93 149 3.3E-16 T 28-03-2018 WM46_RS25705 5a6ea4309e20866bda11947b99368624 149 Pfam PF01476 LysM domain 99 147 2.0E-14 T 28-03-2018 IPR018392 LysM domain WM46_RS25705 5a6ea4309e20866bda11947b99368624 149 SMART SM00257 98 147 3.4E-14 T 28-03-2018 IPR018392 LysM domain WM46_RS25705 5a6ea4309e20866bda11947b99368624 149 Pfam PF04972 BON domain 23 88 1.7E-10 T 28-03-2018 IPR007055 BON domain WM46_RS25705 5a6ea4309e20866bda11947b99368624 149 SUPERFAMILY SSF54106 97 147 4.19E-8 T 28-03-2018 IPR018392 LysM domain WM46_RS25705 5a6ea4309e20866bda11947b99368624 149 SMART SM00749 28 91 1.9E-9 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM46_RS24550 235003f10041f04e1405938737244abf 311 Gene3D G3DSA:3.40.190.10 179 262 2.2E-8 T 28-03-2018 WM46_RS24550 235003f10041f04e1405938737244abf 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24550 235003f10041f04e1405938737244abf 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24550 235003f10041f04e1405938737244abf 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.4E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24550 235003f10041f04e1405938737244abf 311 Gene3D G3DSA:3.40.190.10 96 178 1.5E-7 T 28-03-2018 WM46_RS24550 235003f10041f04e1405938737244abf 311 SUPERFAMILY SSF53850 97 277 2.05E-18 T 28-03-2018 WM46_RS24550 235003f10041f04e1405938737244abf 311 Gene3D G3DSA:1.10.10.10 1 89 1.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24550 235003f10041f04e1405938737244abf 311 SUPERFAMILY SSF46785 7 89 7.82E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24550 235003f10041f04e1405938737244abf 311 Pfam PF03466 LysR substrate binding domain 96 277 8.4E-14 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24550 235003f10041f04e1405938737244abf 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 SUPERFAMILY SSF54211 347 542 4.93E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 435 537 1.7E-10 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 Pfam PF13654 AAA domain 140 288 2.2E-18 T 28-03-2018 WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 Gene3D G3DSA:3.30.230.10 326 568 3.7E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 462 481 8.3E-10 T 28-03-2018 WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 432 451 8.3E-10 T 28-03-2018 WM46_RS09655 dacbd57f166d3a229aaf6705d0e14aea 586 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 8.3E-10 T 28-03-2018 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 SUPERFAMILY SSF50465 336 435 5.76E-30 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 28 434 4.9E-213 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 SUPERFAMILY SSF50447 243 328 8.84E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 34 214 2.1E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 Pfam PF00009 Elongation factor Tu GTP binding domain 27 232 8.8E-44 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 PRINTS PR00315 GTP-binding elongation factor signature 163 172 7.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 PRINTS PR00315 GTP-binding elongation factor signature 126 137 7.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 PRINTS PR00315 GTP-binding elongation factor signature 110 120 7.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 PRINTS PR00315 GTP-binding elongation factor signature 29 42 7.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 PRINTS PR00315 GTP-binding elongation factor signature 90 98 7.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 Gene3D G3DSA:2.40.30.10 240 329 1.5E-22 T 28-03-2018 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 83 98 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 Gene3D G3DSA:3.40.50.300 6 239 2.3E-39 T 28-03-2018 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 Gene3D G3DSA:2.40.30.10 332 436 1.7E-19 T 28-03-2018 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 19 475 53.972 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM46_RS25240 c41f5fb353116ae3b6d035b2aeb37697 475 SUPERFAMILY SSF52540 24 252 1.72E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06520 0864f9eb250678dac5abde10e4f88b8e 653 Gene3D G3DSA:3.20.20.70 7 170 8.2E-8 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS06520 0864f9eb250678dac5abde10e4f88b8e 653 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS06520 0864f9eb250678dac5abde10e4f88b8e 653 Pfam PF12392 Collagenase 391 505 3.0E-17 T 28-03-2018 IPR020988 Peptidase U32, collagenase WM46_RS06520 0864f9eb250678dac5abde10e4f88b8e 653 Pfam PF01136 Peptidase family U32 80 304 5.6E-71 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS04375 d57d739493be102291596b5af0aa34f7 219 Pfam PF04391 Protein of unknown function (DUF533) 33 209 2.5E-48 T 28-03-2018 IPR007486 Inner membrane protein YebE WM46_RS04375 d57d739493be102291596b5af0aa34f7 219 Gene3D G3DSA:1.10.3680.10 75 217 1.2E-15 T 28-03-2018 IPR029024 TerB-like WM46_RS04375 d57d739493be102291596b5af0aa34f7 219 SUPERFAMILY SSF158682 89 213 6.02E-18 T 28-03-2018 WM46_RS18310 e83d3183a9db641bb517098b6797ed3e 158 Pfam PF07977 FabA-like domain 53 135 4.1E-6 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS18310 e83d3183a9db641bb517098b6797ed3e 158 Gene3D G3DSA:3.10.129.10 4 148 1.2E-22 T 28-03-2018 WM46_RS18310 e83d3183a9db641bb517098b6797ed3e 158 PIRSF PIRSF020565 1 157 8.0E-50 T 28-03-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted WM46_RS18310 e83d3183a9db641bb517098b6797ed3e 158 SUPERFAMILY SSF54637 9 145 1.32E-23 T 28-03-2018 IPR029069 HotDog domain WM46_RS02640 96cd7507c179b3f23cf283ab94a4ddb2 181 SUPERFAMILY SSF49401 34 178 3.83E-14 T 28-03-2018 IPR008966 Adhesion domain WM46_RS02640 96cd7507c179b3f23cf283ab94a4ddb2 181 Gene3D G3DSA:2.60.40.1090 31 179 2.8E-20 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS02640 96cd7507c179b3f23cf283ab94a4ddb2 181 Pfam PF00419 Fimbrial protein 35 178 1.6E-10 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 SUPERFAMILY SSF53706 351 650 8.51E-136 T 28-03-2018 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 SUPERFAMILY SSF53706 53 293 8.51E-136 T 28-03-2018 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Gene3D G3DSA:3.30.2070.10 530 574 3.4E-10 T 28-03-2018 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Pfam PF00384 Molybdopterin oxidoreductase 105 569 1.3E-65 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Pfam PF01568 Molydopterin dinucleotide binding domain 666 760 2.5E-19 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 513 530 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Gene3D G3DSA:2.40.40.20 633 775 2.1E-26 T 28-03-2018 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Gene3D G3DSA:3.40.228.10 195 447 2.5E-59 T 28-03-2018 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 SUPERFAMILY SSF50692 654 775 7.23E-29 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Gene3D G3DSA:2.20.25.90 44 106 2.5E-6 T 28-03-2018 WM46_RS12720 89bdd8582cfe5b8f736c5066718767de 777 Gene3D G3DSA:3.40.50.740 107 194 8.1E-14 T 28-03-2018 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 Pfam PF00854 POT family 89 447 1.3E-90 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 SUPERFAMILY SSF103473 15 212 3.14E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 SUPERFAMILY SSF103473 257 492 3.14E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 77 101 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 Gene3D G3DSA:1.20.1250.20 269 497 2.6E-16 T 28-03-2018 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 Hamap MF_01878 Dipeptide and tripeptide permease A [dtpA]. 1 489 49.279 T 28-03-2018 IPR023517 Amino acid/peptide transporter family, dipeptide and tripeptide permease A GO:0006857|GO:0015197|GO:0016020 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 17 485 8.5E-141 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 152 164 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM46_RS07470 9520e5a1bcf813506732e4dd43d81d8b 501 Gene3D G3DSA:1.20.1250.20 8 210 5.4E-25 T 28-03-2018 WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 5.2E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 5.2E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 5.2E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 Gene3D G3DSA:3.40.50.1000 3 31 0.12 T 28-03-2018 IPR023214 HAD-like domain WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 92 191 1.6E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 SUPERFAMILY SSF56784 7 215 4.2E-48 T 28-03-2018 IPR023214 HAD-like domain WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 191 1.2E-22 T 28-03-2018 IPR023214 HAD-like domain WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 Gene3D G3DSA:1.10.150.240 32 79 9.8E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS08090 bd23a95772727afd36487d8ac8173274 222 Gene3D G3DSA:3.40.50.1000 80 218 2.9E-26 T 28-03-2018 IPR023214 HAD-like domain WM46_RS08660 c21eb0b3dd6c050cb71418cfe9769afd 340 Gene3D G3DSA:3.30.160.60 303 337 2.5E-14 T 28-03-2018 WM46_RS08660 c21eb0b3dd6c050cb71418cfe9769afd 340 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 1 337 3.0E-148 T 28-03-2018 IPR003770 Endolytic murein transglycosylase WM46_RS08660 c21eb0b3dd6c050cb71418cfe9769afd 340 Gene3D G3DSA:3.30.160.60 74 108 2.7E-18 T 28-03-2018 WM46_RS08660 c21eb0b3dd6c050cb71418cfe9769afd 340 Pfam PF02618 YceG-like family 43 328 1.8E-79 T 28-03-2018 IPR003770 Endolytic murein transglycosylase WM46_RS08660 c21eb0b3dd6c050cb71418cfe9769afd 340 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 5 332 33.293 T 28-03-2018 IPR003770 Endolytic murein transglycosylase WM46_RS19320 7a36fa1948796781d703a27a969c39aa 233 Pfam PF09365 Conserved hypothetical protein (DUF2461) 13 218 4.7E-47 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 WM46_RS19320 7a36fa1948796781d703a27a969c39aa 233 PIRSF PIRSF028451 4 227 2.5E-31 T 28-03-2018 IPR015996 Uncharacterised conserved protein UCP028451 WM46_RS19320 7a36fa1948796781d703a27a969c39aa 233 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 10 222 2.7E-33 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Gene3D G3DSA:1.10.10.10 1021 1095 0.027 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 SMART SM00490 308 423 7.4E-13 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Pfam PF08494 DEAD/H associated 680 868 3.3E-70 T 28-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Gene3D G3DSA:3.40.50.300 5 229 5.1E-34 T 28-03-2018 WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Gene3D G3DSA:1.10.10.10 940 981 0.022 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Gene3D G3DSA:3.40.50.300 272 439 6.4E-23 T 28-03-2018 WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 SMART SM00382 42 406 0.0058 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Pfam PF00270 DEAD/DEAH box helicase 30 220 7.5E-25 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 SMART SM00487 25 251 2.1E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 SUPERFAMILY SSF52540 42 222 5.77E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 SUPERFAMILY SSF52540 269 316 5.77E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 SUPERFAMILY SSF52540 350 423 5.77E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Gene3D G3DSA:1.10.10.10 1195 1432 1.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07590 97e2ae20caab534cf5295bd8a1456fe7 1557 Pfam PF00271 Helicase conserved C-terminal domain 347 418 2.5E-11 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS20210 dc63f10bcd5a5e2f3435e68135c26d06 284 Gene3D G3DSA:3.90.1480.10 6 279 2.2E-34 T 28-03-2018 WM46_RS20210 dc63f10bcd5a5e2f3435e68135c26d06 284 TIGRFAM TIGR04437 WaaZ_KDO_III: 3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ 6 256 5.6E-128 T 28-03-2018 IPR031026 3-deoxy-D-manno-oct-2-ulosonate III transferase WaaZ WM46_RS20210 dc63f10bcd5a5e2f3435e68135c26d06 284 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 1 259 2.0E-103 T 28-03-2018 WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 SMART SM00642 193 637 3.3E-79 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 Pfam PF00128 Alpha amylase, catalytic domain 226 595 1.5E-34 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 Gene3D G3DSA:2.60.40.1180 123 171 0.012 T 28-03-2018 WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 Gene3D G3DSA:3.20.20.80 184 647 4.5E-75 T 28-03-2018 WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 PIRSF PIRSF036917 1 676 0.0 T 28-03-2018 IPR014635 Alpha-amylase, MalS type GO:0004556|GO:0005509|GO:0030980|GO:0042597|GO:0051692 KEGG: 00500+3.2.1.1 WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 SUPERFAMILY SSF51445 374 643 8.13E-74 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS20420 e36c498ed4fba805d93a68e8903cb80b 676 SUPERFAMILY SSF51445 178 318 8.13E-74 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS20350 6719ac49e11992562344f7094af3300a 378 Gene3D G3DSA:2.40.50.100 63 136 8.2E-13 T 28-03-2018 WM46_RS20350 6719ac49e11992562344f7094af3300a 378 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 301 7.9E-9 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS20350 6719ac49e11992562344f7094af3300a 378 Gene3D G3DSA:2.40.50.100 212 358 7.7E-5 T 28-03-2018 WM46_RS20350 6719ac49e11992562344f7094af3300a 378 Pfam PF00529 HlyD membrane-fusion protein of T1SS 12 367 1.3E-12 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS20350 6719ac49e11992562344f7094af3300a 378 SUPERFAMILY SSF111369 198 266 1.19E-13 T 28-03-2018 WM46_RS20350 6719ac49e11992562344f7094af3300a 378 SUPERFAMILY SSF111369 60 118 1.19E-13 T 28-03-2018 WM46_RS20350 6719ac49e11992562344f7094af3300a 378 SUPERFAMILY SSF111369 147 165 1.19E-13 T 28-03-2018 WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 Gene3D G3DSA:1.10.287.1080 3 122 1.1E-41 T 28-03-2018 WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 SUPERFAMILY SSF101386 2 105 8.83E-26 T 28-03-2018 WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 Gene3D G3DSA:1.10.287.1080 137 262 2.0E-26 T 28-03-2018 WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 SUPERFAMILY SSF101386 135 236 5.23E-25 T 28-03-2018 WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 TIGRFAM TIGR00444 mazG: MazG family protein 10 257 1.4E-122 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 100 2.9E-28 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core WM46_RS25120 7309ef674855aa6c7a4b5372e0ddee83 263 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 169 227 7.2E-9 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 28.664 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 Pfam PF00238 Ribosomal protein L14p/L23e 1 123 6.9E-55 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 4.4E-60 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 SMART SM01374 1 123 3.9E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 Gene3D G3DSA:2.40.150.20 1 123 2.9E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM46_RS17495 085432ff5f62d9b40e7465024b6fef37 123 SUPERFAMILY SSF50193 2 122 1.57E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 WM46_RS07415 d396183691cbba8960f76d58210a1bec 346 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 241 5.2E-20 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS07415 d396183691cbba8960f76d58210a1bec 346 SUPERFAMILY SSF51735 2 191 3.64E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07415 d396183691cbba8960f76d58210a1bec 346 Gene3D G3DSA:3.40.50.720 1 135 4.9E-36 T 28-03-2018 WM46_RS07415 d396183691cbba8960f76d58210a1bec 346 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 1.2E-25 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS07415 d396183691cbba8960f76d58210a1bec 346 Gene3D G3DSA:3.30.360.10 136 346 2.5E-36 T 28-03-2018 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 SMART SM00382 156 299 6.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 Gene3D G3DSA:1.10.8.60 309 381 7.9E-22 T 28-03-2018 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 SUPERFAMILY SSF52172 5 180 2.7E-43 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 SUPERFAMILY SSF46689 387 437 3.17E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 Gene3D G3DSA:3.40.50.2300 1 127 3.5E-34 T 28-03-2018 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 Gene3D G3DSA:1.10.10.60 382 439 9.9E-9 T 28-03-2018 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 Pfam PF00158 Sigma-54 interaction domain 136 302 4.8E-72 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 SMART SM00448 6 117 4.5E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 Gene3D G3DSA:3.40.50.300 131 308 1.1E-25 T 28-03-2018 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 160 173 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 Pfam PF00072 Response regulator receiver domain 9 117 4.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 349 358 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS00490 94ae6eaa9f22089b94a4803d502bc19a 444 SUPERFAMILY SSF52540 136 380 2.23E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 SUPERFAMILY SSF52540 175 284 1.36E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Gene3D G3DSA:3.40.630.30 337 600 5.7E-15 T 28-03-2018 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Pfam PF05127 Helicase 197 337 3.3E-41 T 28-03-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Gene3D G3DSA:3.40.50.300 170 321 1.6E-4 T 28-03-2018 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Pfam PF08351 Domain of unknown function (DUF1726) 66 146 6.8E-6 T 28-03-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Pfam PF13718 GNAT acetyltransferase 2 370 479 7.4E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Pfam PF13718 GNAT acetyltransferase 2 480 531 1.3E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Pfam PF17176 tRNA-binding domain 535 652 4.0E-37 T 28-03-2018 IPR033442 tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain KEGG: 00650+2.3.1.19 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 18 650 48.305 T 28-03-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 KEGG: 00650+2.3.1.19 WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 SUPERFAMILY SSF55729 368 418 2.34E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS00870 df25acfeabc62defeeca05036ab8fceb 669 SUPERFAMILY SSF55729 454 511 2.34E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS21610 201a140c222f6938d95c32c3d624eeb6 171 SUPERFAMILY SSF46785 12 144 6.23E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21610 201a140c222f6938d95c32c3d624eeb6 171 Gene3D G3DSA:1.10.10.10 1 92 6.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21610 201a140c222f6938d95c32c3d624eeb6 171 Pfam PF01475 Ferric uptake regulator family 20 138 2.4E-15 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 WM46_RS21890 23f23a0a43d5432781caf3f77f928b86 338 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 4 291 1.7E-111 T 28-03-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 WM46_RS21890 23f23a0a43d5432781caf3f77f928b86 338 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 35 277 6.0E-71 T 28-03-2018 WM46_RS21890 23f23a0a43d5432781caf3f77f928b86 338 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 6 254 1.5E-92 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 WM46_RS21890 23f23a0a43d5432781caf3f77f928b86 338 Gene3D G3DSA:3.40.190.10 22 126 2.5E-7 T 28-03-2018 WM46_RS21890 23f23a0a43d5432781caf3f77f928b86 338 Gene3D G3DSA:3.40.190.10 127 276 2.6E-30 T 28-03-2018 WM46_RS21890 23f23a0a43d5432781caf3f77f928b86 338 SUPERFAMILY SSF53850 54 245 4.54E-44 T 28-03-2018 WM46_RS09445 f9df2c901713a5a1fa48950f13cb5107 286 SUPERFAMILY SSF51569 4 282 3.08E-89 T 28-03-2018 WM46_RS09445 f9df2c901713a5a1fa48950f13cb5107 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 282 2.0E-80 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS09445 f9df2c901713a5a1fa48950f13cb5107 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 281 1.5E-92 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS09445 f9df2c901713a5a1fa48950f13cb5107 286 PIRSF PIRSF001359 1 282 4.1E-93 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS09445 f9df2c901713a5a1fa48950f13cb5107 286 Gene3D G3DSA:3.20.20.70 2 286 6.7E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 Pfam PF13646 HEAT repeats 167 228 4.5E-7 T 28-03-2018 WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 Pfam PF02653 Branched-chain amino acid transport system / permease component 232 507 8.4E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 Gene3D G3DSA:1.10.3470.10 207 511 1.3E-49 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 Gene3D G3DSA:1.25.10.20 102 167 0.016 T 28-03-2018 WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 230 521 2.3E-127 T 28-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 SUPERFAMILY SSF48371 114 228 2.73E-9 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 WM46_RS07115 ec4a412aa336cc90ebf7a0d7c57017d2 524 Gene3D G3DSA:1.25.40.70 168 206 1.7E-6 T 28-03-2018 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 Gene3D G3DSA:1.20.5.570 463 490 5.5E-19 T 28-03-2018 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 SUPERFAMILY SSF50475 6 325 1.02E-129 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 SUPERFAMILY SSF143968 326 489 1.7E-66 T 28-03-2018 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 14 434 4.2E-174 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 Gene3D G3DSA:3.40.1670.10 326 462 2.3E-52 T 28-03-2018 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 9 458 6.6E-191 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 WM46_RS18975 de324a98f9654eefe1c2432b1d30bd3f 497 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 4 490 73.807 T 28-03-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 WM46_RS13235 b1023eec0068a1506250ff2ee5ae0fc5 281 SUPERFAMILY SSF53335 49 264 4.37E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS13235 b1023eec0068a1506250ff2ee5ae0fc5 281 Gene3D G3DSA:3.40.50.150 32 278 5.2E-34 T 28-03-2018 WM46_RS13235 b1023eec0068a1506250ff2ee5ae0fc5 281 Pfam PF13649 Methyltransferase domain 69 163 2.6E-21 T 28-03-2018 WM46_RS09160 ffae6f0d8860103a68ed4ee29b7f3427 413 Pfam PF00328 Histidine phosphatase superfamily (branch 2) 31 363 1.5E-16 T 28-03-2018 IPR000560 Histidine phosphatase superfamily, clade-2 GO:0003993 WM46_RS09160 ffae6f0d8860103a68ed4ee29b7f3427 413 SUPERFAMILY SSF53254 25 410 9.42E-77 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS09160 ffae6f0d8860103a68ed4ee29b7f3427 413 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 31 45 - T 28-03-2018 IPR033379 Histidine acid phosphatase active site WM46_RS09160 ffae6f0d8860103a68ed4ee29b7f3427 413 ProSitePatterns PS00778 Histidine acid phosphatases active site signature. 305 321 - T 28-03-2018 IPR033379 Histidine acid phosphatase active site WM46_RS09160 ffae6f0d8860103a68ed4ee29b7f3427 413 Gene3D G3DSA:3.40.50.1240 53 84 0.3 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS09160 ffae6f0d8860103a68ed4ee29b7f3427 413 Gene3D G3DSA:3.40.50.1240 137 272 8.6E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS08280 931a6142377e7f717d6aeaded527fadc 512 Gene3D G3DSA:3.30.1360.60 435 510 1.1E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS08280 931a6142377e7f717d6aeaded527fadc 512 Pfam PF02378 Phosphotransferase system, EIIC 12 350 1.5E-84 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS08280 931a6142377e7f717d6aeaded527fadc 512 SUPERFAMILY SSF55604 437 510 6.93E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS08280 931a6142377e7f717d6aeaded527fadc 512 Pfam PF00367 phosphotransferase system, EIIB 441 470 4.7E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS08280 931a6142377e7f717d6aeaded527fadc 512 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 415 496 8.3E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS08280 931a6142377e7f717d6aeaded527fadc 512 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 450 467 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS21870 2074cf7b9bc947754e3eb8029ba8d5b2 194 SUPERFAMILY SSF159709 13 193 2.09E-58 T 28-03-2018 WM46_RS21870 2074cf7b9bc947754e3eb8029ba8d5b2 194 PIRSF PIRSF020680 1 194 1.1E-65 T 28-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 WM46_RS21870 2074cf7b9bc947754e3eb8029ba8d5b2 194 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 6 192 3.2E-63 T 28-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 WM46_RS21870 2074cf7b9bc947754e3eb8029ba8d5b2 194 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 7 190 7.2E-60 T 28-03-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 SUPERFAMILY SSF57716 142 191 9.27E-17 T 28-03-2018 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 SUPERFAMILY SSF52540 1 141 1.71E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 Hamap MF_00124 Thymidine kinase [tdk]. 1 189 35.347 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 Gene3D G3DSA:3.30.60.20 142 193 6.0E-19 T 28-03-2018 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 173 186 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 Pfam PF00265 Thymidine kinase 2 186 5.0E-66 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 Gene3D G3DSA:3.40.50.300 2 141 4.4E-45 T 28-03-2018 WM46_RS05725 969cb76915a45fe4eb6e30cb58f9ac49 205 PIRSF PIRSF035805 1 200 5.1E-58 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 Gene3D G3DSA:1.10.3370.10 12 439 1.5E-160 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 Pfam PF00344 SecY translocase 76 417 6.5E-120 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 433 29.964 T 28-03-2018 IPR026593 Protein translocase subunit SecY WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PIRSF PIRSF004557 11 441 4.3E-124 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 7.7E-99 T 28-03-2018 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 SUPERFAMILY SSF103491 16 424 3.53E-134 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 429 1.5E-141 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS17445 94f7684647872b8ce2e068cf6725031c 443 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 Hamap MF_00509 Cell division protein ZipA [zipA]. 3 334 25.163 T 28-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 SMART SM00771 203 332 2.1E-75 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 205 340 3.0E-73 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 Gene3D G3DSA:3.30.1400.10 204 335 1.3E-54 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 SUPERFAMILY SSF64383 204 337 6.67E-49 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 206 331 3.5E-48 T 28-03-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 WM46_RS01150 33493d8c584b51b1e007e7d801ae973a 340 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 4 332 3.3E-107 T 28-03-2018 IPR011919 Cell division protein ZipA GO:0007049|GO:0016021|GO:0090529 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 SUPERFAMILY SSF141734 6 121 9.94E-47 T 28-03-2018 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 116 202 1.9E-16 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 17.413 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 105 4.0E-24 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 Gene3D G3DSA:1.10.287.1080 111 203 2.4E-18 T 28-03-2018 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 203 37.561 T 28-03-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 3.4E-31 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 SUPERFAMILY SSF101386 115 202 2.62E-22 T 28-03-2018 WM46_RS03005 240758ac49aae9058ba761b26b41091b 203 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 8.9E-29 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 WM46_RS12820 dce9e29a91a989e29b1179c83308b781 375 Gene3D G3DSA:3.20.20.105 1 368 5.0E-160 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM46_RS12820 dce9e29a91a989e29b1179c83308b781 375 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 361 1.6E-93 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM46_RS12820 dce9e29a91a989e29b1179c83308b781 375 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 364 57.731 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM46_RS12820 dce9e29a91a989e29b1179c83308b781 375 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 367 7.5E-181 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM46_RS12820 dce9e29a91a989e29b1179c83308b781 375 SUPERFAMILY SSF51713 1 364 1.02E-163 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM46_RS12820 dce9e29a91a989e29b1179c83308b781 375 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 368 5.7E-191 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Gene3D G3DSA:2.40.40.20 677 814 5.1E-36 T 28-03-2018 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 14 45 8.4E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 SMART SM00926 56 116 1.1E-9 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 SUPERFAMILY SSF53706 57 697 6.67E-182 T 28-03-2018 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 TIGRFAM TIGR02166 dmsA_ynfE: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family 14 814 0.0 T 28-03-2018 IPR011888 Anaerobic dimethyl sulphoxide reductase, subunit A, DmsA/YnfE GO:0009389|GO:0030151|GO:0051539|GO:0055114 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 731 758 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Gene3D G3DSA:3.40.228.10 205 489 7.0E-65 T 28-03-2018 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Gene3D G3DSA:2.20.25.90 50 121 8.7E-19 T 28-03-2018 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 61 79 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Pfam PF01568 Molydopterin dinucleotide binding domain 695 806 6.0E-28 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 517 534 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 SUPERFAMILY SSF50692 641 814 4.52E-40 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Gene3D G3DSA:3.90.55.10 539 610 4.7E-22 T 28-03-2018 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Gene3D G3DSA:3.40.228.10 611 676 5.1E-13 T 28-03-2018 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Pfam PF00384 Molybdopterin oxidoreductase 119 576 5.0E-111 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS09920 91c2a71167f9f6e38ab2f5cf53a0655a 814 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 56 116 1.0E-17 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS03565 109adc4eacdb66232224ef81d1280def 201 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 179 6.2E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03565 109adc4eacdb66232224ef81d1280def 201 Gene3D G3DSA:3.40.1010.10 1 111 2.8E-22 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03565 109adc4eacdb66232224ef81d1280def 201 Gene3D G3DSA:3.30.950.10 112 201 6.9E-22 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03565 109adc4eacdb66232224ef81d1280def 201 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 195 2.1E-61 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 WM46_RS03565 109adc4eacdb66232224ef81d1280def 201 SUPERFAMILY SSF53790 1 198 7.2E-44 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 Gene3D G3DSA:3.20.20.100 5 291 3.4E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 PRINTS PR00069 Aldo-keto reductase signature 49 73 7.2E-11 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 PRINTS PR00069 Aldo-keto reductase signature 114 132 7.2E-11 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 PRINTS PR00069 Aldo-keto reductase signature 151 168 7.2E-11 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 PRINTS PR00069 Aldo-keto reductase signature 221 245 7.2E-11 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 SUPERFAMILY SSF51430 15 289 1.26E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS06310 3d05ac7ede1e07e70ba69ae48ad9c586 291 Pfam PF00248 Aldo/keto reductase family 19 288 7.0E-49 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 Gene3D G3DSA:3.40.50.300 253 424 5.9E-46 T 28-03-2018 WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 SMART SM00490 304 404 1.5E-15 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 Pfam PF11898 Domain of unknown function (DUF3418) 713 1297 4.4E-237 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 SMART SM00382 92 384 3.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 622 698 2.3E-18 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 Gene3D G3DSA:3.40.50.300 76 235 2.7E-29 T 28-03-2018 WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 Pfam PF04408 Helicase associated domain (HA2) 466 557 3.0E-17 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 SMART SM00847 464 559 1.1E-37 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 Pfam PF00271 Helicase conserved C-terminal domain 286 403 2.3E-11 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 SMART SM00487 75 259 1.3E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 SUPERFAMILY SSF52540 74 601 2.23E-110 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06325 5f650bed3a7a807e4599f52643c2799e 1300 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 13 1297 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 Pfam PF00999 Sodium/hydrogen exchanger family 11 375 1.3E-62 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 Gene3D G3DSA:3.40.50.720 396 560 5.5E-24 T 28-03-2018 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 Hamap MF_01413 Glutathione-regulated potassium-efflux system protein KefC [kefC]. 1 607 55.53 T 28-03-2018 IPR023941 Glutathione-regulated potassium-efflux system protein KefC GO:0005887|GO:0006813|GO:0015503|GO:0015643|GO:0019899|GO:0051595 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 PRINTS PR00335 TrkA potassium uptake protein signature 458 468 2.0E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 PRINTS PR00335 TrkA potassium uptake protein signature 418 432 2.0E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 PRINTS PR00335 TrkA potassium uptake protein signature 401 415 2.0E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 PRINTS PR00335 TrkA potassium uptake protein signature 447 457 2.0E-8 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 Pfam PF02254 TrkA-N domain 402 512 1.9E-25 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 Gene3D G3DSA:1.20.91.10 232 311 3.1E-12 T 28-03-2018 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 285 5.9E-93 T 28-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 WM46_RS14590 dacefb90145b5e1828346490ce512922 620 SUPERFAMILY SSF51735 401 529 9.88E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 6.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 6.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 PIRSF PIRSF000094 1 260 3.9E-125 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 SUPERFAMILY SSF51735 6 253 1.33E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 3.7E-85 T 28-03-2018 WM46_RS05980 e6eb61eff6894d6e429c5194f2fa2800 262 Gene3D G3DSA:3.40.50.720 3 261 5.1E-44 T 28-03-2018 WM46_RS09640 e4eb7d5783799bc5e9161ab393159db5 169 Pfam PF03846 Cell division inhibitor SulA 7 119 5.6E-54 T 28-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 WM46_RS09640 e4eb7d5783799bc5e9161ab393159db5 169 Hamap MF_01179 Cell division inhibitor SulA [sulA]. 1 169 41.987 T 28-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 WM46_RS09640 e4eb7d5783799bc5e9161ab393159db5 169 SUPERFAMILY SSF52540 31 147 1.27E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09640 e4eb7d5783799bc5e9161ab393159db5 169 TIGRFAM TIGR00623 sula: cell division inhibitor SulA 2 169 9.1E-97 T 28-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 WM46_RS09640 e4eb7d5783799bc5e9161ab393159db5 169 PIRSF PIRSF003093 1 169 1.5E-86 T 28-03-2018 IPR004596 Cell division suppressor protein, SulA GO:0009432|GO:0051782 WM46_RS09640 e4eb7d5783799bc5e9161ab393159db5 169 Gene3D G3DSA:3.40.50.300 31 148 5.2E-17 T 28-03-2018 WM46_RS01880 564fd7acff986ae3f35c4d149612d938 128 SUPERFAMILY SSF103481 47 125 1.05E-5 T 28-03-2018 WM46_RS01880 564fd7acff986ae3f35c4d149612d938 128 Hamap MF_00538 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF [arnF]. 1 125 20.101 T 28-03-2018 IPR022832 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF WM46_RS04180 587386e7f08668119da3b215c7204221 349 Pfam PF01339 CheB methylesterase 159 336 4.8E-63 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 WM46_RS04180 587386e7f08668119da3b215c7204221 349 Gene3D G3DSA:3.40.50.2300 1 143 5.7E-27 T 28-03-2018 WM46_RS04180 587386e7f08668119da3b215c7204221 349 SUPERFAMILY SSF52172 1 108 8.11E-28 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS04180 587386e7f08668119da3b215c7204221 349 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 342 41.342 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 WM46_RS04180 587386e7f08668119da3b215c7204221 349 SUPERFAMILY SSF52738 156 342 3.14E-75 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 WM46_RS04180 587386e7f08668119da3b215c7204221 349 Gene3D G3DSA:3.40.50.180 149 349 2.6E-80 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 WM46_RS04180 587386e7f08668119da3b215c7204221 349 PIRSF PIRSF000876 1 346 9.0E-138 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 WM46_RS04180 587386e7f08668119da3b215c7204221 349 SMART SM00448 4 119 2.2E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS04180 587386e7f08668119da3b215c7204221 349 Pfam PF00072 Response regulator receiver domain 6 109 1.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 66 157 8.4E-8 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 SUPERFAMILY SSF51604 145 397 7.73E-55 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 1 401 79.758 T 28-03-2018 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 132 157 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 Pfam PF13378 Enolase C-terminal domain-like 183 392 1.1E-36 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 SUPERFAMILY SSF54826 41 158 4.46E-23 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 Gene3D G3DSA:3.20.20.120 160 390 3.2E-46 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 SMART SM00922 163 269 7.5E-8 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS01940 58ad7f76acdef3d516a0979189761579 401 Gene3D G3DSA:3.30.390.10 1 159 9.5E-48 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 PIRSF PIRSF500176 22 348 2.9E-83 T 28-03-2018 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 28 36 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 Pfam PF00710 Asparaginase, N-terminal 25 216 7.3E-64 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 Gene3D G3DSA:3.40.50.40 235 347 7.2E-32 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 PRINTS PR00139 Asparaginase/glutaminase family signature 103 121 5.5E-23 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 PRINTS PR00139 Asparaginase/glutaminase family signature 26 37 5.5E-23 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 PRINTS PR00139 Asparaginase/glutaminase family signature 282 300 5.5E-23 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 SMART SM00870 25 342 5.6E-147 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 104 114 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 Gene3D G3DSA:3.40.50.1170 21 231 1.1E-64 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 PIRSF PIRSF001220 20 348 1.2E-93 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 1 348 6.9E-167 T 28-03-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 WM46_RS15110 dd02560de2f367111be9389c378bcc9f 348 SUPERFAMILY SSF53774 23 347 1.96E-109 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 PIRSF PIRSF001359 13 359 1.8E-106 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 358 9.7E-193 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 355 6.3E-89 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 101 112 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 172 183 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 357 1.8E-117 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 SUPERFAMILY SSF51569 4 357 1.23E-131 T 28-03-2018 WM46_RS14930 d7a2c5fe26154d217cdb24949bd50a7c 359 Gene3D G3DSA:3.20.20.70 4 358 5.1E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS11185 3182d57a9f5eb5be77b6a5a2ad4ae494 379 SUPERFAMILY SSF103501 157 370 1.09E-32 T 28-03-2018 IPR023234 NarG-like domain WM46_RS11185 3182d57a9f5eb5be77b6a5a2ad4ae494 379 TIGRFAM TIGR02484 CitB: CitB domain protein 15 375 4.0E-119 T 28-03-2018 IPR012830 Citrate utilization protein B WM46_RS11185 3182d57a9f5eb5be77b6a5a2ad4ae494 379 Gene3D G3DSA:1.20.950.20 152 363 1.3E-29 T 28-03-2018 WM46_RS11185 3182d57a9f5eb5be77b6a5a2ad4ae494 379 Gene3D G3DSA:3.30.70.20 5 101 7.7E-5 T 28-03-2018 WM46_RS11185 3182d57a9f5eb5be77b6a5a2ad4ae494 379 SUPERFAMILY SSF54862 20 108 1.53E-6 T 28-03-2018 WM46_RS21235 4173f4d7df21b0117cc93c9557b921b3 211 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 20 202 6.1E-59 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS21235 4173f4d7df21b0117cc93c9557b921b3 211 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 10 207 20.177 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS21235 4173f4d7df21b0117cc93c9557b921b3 211 Gene3D G3DSA:3.20.20.70 12 206 3.6E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS21235 4173f4d7df21b0117cc93c9557b921b3 211 Pfam PF02581 Thiamine monophosphate synthase 20 189 9.3E-56 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS21235 4173f4d7df21b0117cc93c9557b921b3 211 SUPERFAMILY SSF51391 5 204 3.01E-64 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS25305 b98edd322bbe56f062dc569d92bb7e41 197 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 183 4.1E-73 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 WM46_RS25305 b98edd322bbe56f062dc569d92bb7e41 197 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 185 36.797 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 WM46_RS25305 b98edd322bbe56f062dc569d92bb7e41 197 Gene3D G3DSA:3.40.50.1950 1 197 3.8E-57 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS25305 b98edd322bbe56f062dc569d92bb7e41 197 SUPERFAMILY SSF52507 1 185 5.23E-64 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS25305 b98edd322bbe56f062dc569d92bb7e41 197 Pfam PF02441 Flavoprotein 1 164 2.8E-25 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS25305 b98edd322bbe56f062dc569d92bb7e41 197 Hamap MF_01986 Probable UbiX-like flavin prenyltransferase. 1 189 52.728 T 28-03-2018 IPR032901 Probable UbiX-like flavin prenyltransferase WM46_RS18795 01b8a8e3eb1b0d18635c19311813f052 297 Gene3D G3DSA:2.70.98.10 2 293 5.4E-68 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS18795 01b8a8e3eb1b0d18635c19311813f052 297 SUPERFAMILY SSF74650 8 290 6.22E-62 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS18795 01b8a8e3eb1b0d18635c19311813f052 297 Pfam PF01263 Aldose 1-epimerase 11 288 4.2E-50 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 WM46_RS25420 dde6a2ef9fc164738e3611e99e3eda46 136 Pfam PF07450 Formate hydrogenlyase maturation protein HycH 4 133 1.3E-55 T 28-03-2018 IPR010005 Formate hydrogenlyase maturation HycH WM46_RS25420 dde6a2ef9fc164738e3611e99e3eda46 136 ProDom PD021295 MATURATION HYDROGENLYASE FORMATE HYCH LYASE HYCE PROCESSING OXIDOREDUCTASE J COMPONENT 1 133 2.0E-67 T 28-03-2018 IPR010005 Formate hydrogenlyase maturation HycH WM46_RS04810 4922800c36e5c159d79b4f81498f7084 402 Gene3D G3DSA:1.10.10.10 270 402 4.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04810 4922800c36e5c159d79b4f81498f7084 402 Pfam PF13884 Chaperone of endosialidase 281 333 5.1E-9 T 28-03-2018 IPR030392 Intramolecular chaperone auto-processing domain WM46_RS07100 f01d41568708fdb1f58ea77b30cf6ba5 232 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 232 1.9E-106 T 28-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE WM46_RS07100 f01d41568708fdb1f58ea77b30cf6ba5 232 Gene3D G3DSA:3.40.50.300 1 227 2.0E-56 T 28-03-2018 WM46_RS07100 f01d41568708fdb1f58ea77b30cf6ba5 232 SUPERFAMILY SSF52540 2 221 3.0E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07100 f01d41568708fdb1f58ea77b30cf6ba5 232 Pfam PF00005 ABC transporter 17 161 8.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07100 f01d41568708fdb1f58ea77b30cf6ba5 232 SMART SM00382 26 219 4.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00412 Epoxide hydrolase signature 32 50 3.6E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 3.6E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00412 Epoxide hydrolase signature 52 67 3.6E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 3.6E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 SUPERFAMILY SSF53474 6 277 1.69E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 4.5E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 4.5E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 4.5E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 Pfam PF12146 Serine aminopeptidase, S33 28 261 9.5E-24 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 WM46_RS11520 02f6273a316ca5ad4fd8e86d2632b8ea 278 Gene3D G3DSA:3.40.50.1820 4 278 1.3E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS03295 a1f54ab5397f3107e170f2ba0ea4c6a0 349 Pfam PF03864 Phage major capsid protein E 5 347 1.7E-81 T 28-03-2018 IPR005564 Major capsid protein GpE GO:0019028 WM46_RS03295 a1f54ab5397f3107e170f2ba0ea4c6a0 349 Gene3D G3DSA:3.90.1690.10 2 349 1.4E-69 T 28-03-2018 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 Pfam PF00085 Thioredoxin 37 137 5.7E-28 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 PIRSF PIRSF000077 36 139 7.5E-33 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 SUPERFAMILY SSF52833 24 138 4.23E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 TIGRFAM TIGR01068 thioredoxin: thioredoxin 45 138 6.9E-37 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 Gene3D G3DSA:3.40.30.10 33 139 3.0E-35 T 28-03-2018 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 PRINTS PR00421 Thioredoxin family signature 55 63 1.7E-9 T 28-03-2018 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 PRINTS PR00421 Thioredoxin family signature 103 114 1.7E-9 T 28-03-2018 WM46_RS00330 b7c96557a1d37fdb0f7d4626fa2095fc 139 PRINTS PR00421 Thioredoxin family signature 63 72 1.7E-9 T 28-03-2018 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 Pfam PF01578 Cytochrome C assembly protein 7 184 3.7E-32 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 156 182 6.1E-64 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 62 82 6.1E-64 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 100 120 6.1E-64 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 45 62 6.1E-64 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 201 225 6.1E-64 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 121 141 6.1E-64 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02175 bd1dd3cce7311f93bc74b1eb7946da82 245 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 45 225 4.4E-84 T 28-03-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS03065 ed69a0b64b971a833f032f6d46061a30 455 Pfam PF13520 Amino acid permease 51 410 9.6E-35 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS03065 ed69a0b64b971a833f032f6d46061a30 455 PIRSF PIRSF006060 3 449 3.8E-70 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 SUPERFAMILY SSF52794 377 466 2.98E-22 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 Pfam PF02378 Phosphotransferase system, EIIC 17 277 9.3E-19 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 379 453 6.4E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 SUPERFAMILY SSF55804 496 634 1.96E-41 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 539 555 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 Gene3D G3DSA:3.40.50.2300 365 471 1.1E-20 T 28-03-2018 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 Gene3D G3DSA:3.40.930.10 492 637 2.4E-36 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 498 634 2.1E-33 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS20340 e213405bfdf2f94bc42828e0efc1bc25 637 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 8 347 3.2E-188 T 28-03-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 315 754 2.3E-116 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 Gene3D G3DSA:2.40.128.130 433 754 5.5E-53 T 28-03-2018 WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 Pfam PF03797 Autotransporter beta-domain 478 732 1.1E-50 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 SUPERFAMILY SSF51126 312 421 1.22E-33 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 SUPERFAMILY SSF51126 3 271 1.22E-33 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 SUPERFAMILY SSF103515 441 754 6.02E-51 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 Gene3D G3DSA:2.160.20.20 1 425 7.3E-42 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS08450 348dfa47132daedc4b10f896a74ca44e 754 SMART SM00869 475 743 1.6E-43 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13615 b423b86e0d64a3478d4465fd078885a6 383 Gene3D G3DSA:3.40.50.150 2 187 4.9E-21 T 28-03-2018 WM46_RS13615 b423b86e0d64a3478d4465fd078885a6 383 SUPERFAMILY SSF53335 49 229 3.82E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS13615 b423b86e0d64a3478d4465fd078885a6 383 SUPERFAMILY SSF53335 315 374 3.82E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS13615 b423b86e0d64a3478d4465fd078885a6 383 Pfam PF00145 C-5 cytosine-specific DNA methylase 77 170 8.9E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS14655 e7d4dff1eba6fb766308ac90d72bb1f1 198 Hamap MF_01525 Carnitine operon protein CaiE [caiE]. 1 196 57.061 T 28-03-2018 IPR023446 Carnitine operon protein CaiE WM46_RS14655 e7d4dff1eba6fb766308ac90d72bb1f1 198 SUPERFAMILY SSF51161 3 166 5.13E-41 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS14655 e7d4dff1eba6fb766308ac90d72bb1f1 198 Gene3D G3DSA:2.160.10.10 4 175 8.8E-37 T 28-03-2018 WM46_RS14655 e7d4dff1eba6fb766308ac90d72bb1f1 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 41 1.1E-4 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS14655 e7d4dff1eba6fb766308ac90d72bb1f1 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 7.2E-8 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS07095 f5b4fbcdbb94dea2d1d974a09b94916f 395 Gene3D G3DSA:1.20.1250.20 197 385 1.1E-8 T 28-03-2018 WM46_RS07095 f5b4fbcdbb94dea2d1d974a09b94916f 395 Pfam PF07690 Major Facilitator Superfamily 13 341 1.2E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07095 f5b4fbcdbb94dea2d1d974a09b94916f 395 SUPERFAMILY SSF103473 6 384 2.35E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07095 f5b4fbcdbb94dea2d1d974a09b94916f 395 Gene3D G3DSA:1.20.1250.20 3 196 8.6E-25 T 28-03-2018 WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 SUPERFAMILY SSF159871 3 93 1.18E-22 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 Gene3D G3DSA:3.30.1660.10 106 174 4.3E-17 T 28-03-2018 IPR025543 Dodecin-like WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 Gene3D G3DSA:3.30.1660.10 247 314 1.2E-22 T 28-03-2018 IPR025543 Dodecin-like WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 SUPERFAMILY SSF159871 107 177 6.54E-17 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 SUPERFAMILY SSF159871 239 314 1.83E-18 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 PIRSF PIRSF014774 1 314 2.0E-181 T 28-03-2018 IPR025539 YdgH protein WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 Gene3D G3DSA:3.30.1660.10 22 90 4.5E-20 T 28-03-2018 IPR025543 Dodecin-like WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 Pfam PF07338 Protein of unknown function (DUF1471) 34 90 6.9E-18 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 Pfam PF07338 Protein of unknown function (DUF1471) 259 314 2.2E-20 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS07340 816d03504d0c05c7e3320f2000d9f174 314 Pfam PF07338 Protein of unknown function (DUF1471) 118 174 2.3E-18 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS25870 5ace61ad79cc30fd82776062a5bc4105 180 SUPERFAMILY SSF46785 6 141 2.61E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25870 5ace61ad79cc30fd82776062a5bc4105 180 Gene3D G3DSA:1.10.10.10 6 148 3.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25870 5ace61ad79cc30fd82776062a5bc4105 180 Pfam PF01051 Initiator Replication protein 8 176 8.0E-29 T 28-03-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 WM46_RS22230 8d92147911cfb8dc7e361b9f5d5c86ed 556 TIGRFAM TIGR02520 pilus_B_mal_scr: type IVB pilus formation outer membrane protein, R64 PilN family 59 554 1.5E-118 T 28-03-2018 IPR013359 Pilus formation type IVB, outer membrane PilN WM46_RS22230 8d92147911cfb8dc7e361b9f5d5c86ed 556 Pfam PF07655 Secretin N-terminal domain 207 283 5.8E-7 T 28-03-2018 IPR011514 Secretin, N-terminal GO:0009297|GO:0019867 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 SUPERFAMILY SSF47781 405 555 1.33E-15 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 SUPERFAMILY SSF56091 25 307 3.04E-65 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Gene3D G3DSA:3.30.1490.70 235 312 6.6E-7 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 SUPERFAMILY SSF50249 311 388 1.88E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Gene3D G3DSA:1.10.150.20 483 541 0.035 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Gene3D G3DSA:1.10.150.20 410 482 1.4E-7 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Gene3D G3DSA:3.30.470.30 129 234 2.2E-17 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 SMART SM00532 29 426 6.9E-92 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Gene3D G3DSA:2.40.50.140 313 381 1.9E-16 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Gene3D G3DSA:1.10.287.610 24 94 3.5E-12 T 28-03-2018 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 313 387 1.0E-18 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 125 154 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Hamap MF_01587 DNA ligase B [ligB]. 1 559 51.414 T 28-03-2018 IPR020923 DNA ligase B GO:0003911|GO:0006259 WM46_RS20095 9de30123600d0dcc0f1624e476bc3a2d 561 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 30 307 2.0E-27 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 SMART SM00862 149 225 7.5E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 SUPERFAMILY SSF52172 1 124 9.68E-43 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 Gene3D G3DSA:3.40.50.2300 1 121 1.1E-39 T 28-03-2018 WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 1.0E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 SUPERFAMILY SSF46894 127 225 2.61E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 Gene3D G3DSA:1.10.10.10 122 228 2.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 SMART SM00448 1 112 6.9E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS18710 0860fd7375a8d91f530ba0c1a323e04d 228 Pfam PF00072 Response regulator receiver domain 3 113 2.5E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS15555 bb2a98a6046d31e4ad0e3c66c231771e 679 SUPERFAMILY SSF52540 121 319 5.31E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15555 bb2a98a6046d31e4ad0e3c66c231771e 679 SUPERFAMILY SSF52540 375 630 5.31E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15555 bb2a98a6046d31e4ad0e3c66c231771e 679 Pfam PF12696 TraM recognition site of TraD and TraG 485 611 1.2E-10 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site WM46_RS15555 bb2a98a6046d31e4ad0e3c66c231771e 679 Gene3D G3DSA:3.40.50.300 82 638 3.3E-26 T 28-03-2018 WM46_RS15555 bb2a98a6046d31e4ad0e3c66c231771e 679 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 4 632 3.4E-262 T 28-03-2018 IPR022458 Conjugative coupling factor TraG/TraD WM46_RS15555 bb2a98a6046d31e4ad0e3c66c231771e 679 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 5 632 0.0 T 28-03-2018 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 WM46_RS03360 4ffbd1157199ffea88c7947090c8b9be 149 Pfam PF07409 Phage protein GP46 29 138 1.5E-36 T 28-03-2018 IPR010877 Bacteriophage Mu, Gp46 WM46_RS25945 78beef7c33eb98d4a39e31f48af9edcc 162 SUPERFAMILY SSF52980 15 90 2.95E-12 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS25945 78beef7c33eb98d4a39e31f48af9edcc 162 Pfam PF04471 Restriction endonuclease 11 121 4.4E-19 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 WM46_RS25945 78beef7c33eb98d4a39e31f48af9edcc 162 Gene3D G3DSA:3.40.1350.10 5 122 3.3E-14 T 28-03-2018 WM46_RS09885 d0a38e6772b55f9f95bb0869a5ce9fec 315 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 44 309 1.2E-126 T 28-03-2018 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 WM46_RS09885 d0a38e6772b55f9f95bb0869a5ce9fec 315 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 113 122 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site WM46_RS09885 d0a38e6772b55f9f95bb0869a5ce9fec 315 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 56 310 5.2E-95 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 WM46_RS09885 d0a38e6772b55f9f95bb0869a5ce9fec 315 Gene3D G3DSA:1.20.1080.10 42 315 2.9E-79 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS09885 d0a38e6772b55f9f95bb0869a5ce9fec 315 Pfam PF01226 Formate/nitrite transporter 45 306 1.0E-75 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 WM46_RS09885 d0a38e6772b55f9f95bb0869a5ce9fec 315 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 198 208 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 Pfam PF03887 YfbU domain 1 164 2.6E-69 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 PIRSF PIRSF006272 1 164 1.0E-79 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 Gene3D G3DSA:1.10.287.680 1 47 5.4E-26 T 28-03-2018 IPR023145 YfbU, helix-hairpin domain WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 Hamap MF_00762 UPF0304 protein YfbU [yfbU]. 1 164 40.248 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 Gene3D G3DSA:1.10.3190.10 54 164 1.2E-44 T 28-03-2018 IPR023146 YfbU, alpha-helical bundle domain WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 SUPERFAMILY SSF116960 1 164 2.75E-70 T 28-03-2018 WM46_RS01730 f4e6a1595ea06d552bb80b9637f0c9ee 164 ProDom PD035118 UPF0304 YFBU PLASMID YPO2563/Y1624/YP2374 YBFU PM1500 OXYGEN ECA3037 VV12093 PROTEIN 1 164 8.0E-93 T 28-03-2018 IPR005587 Uncharacterised protein family UPF0304, YfbU WM46_RS12375 08b7839adb353912d356a28fdb006849 624 Pfam PF00183 Hsp90 protein 211 622 4.2E-125 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 WM46_RS12375 08b7839adb353912d356a28fdb006849 624 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 623 32.983 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 WM46_RS12375 08b7839adb353912d356a28fdb006849 624 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 25 34 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PIRSF PIRSF002583 1 624 1.9E-219 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 WM46_RS12375 08b7839adb353912d356a28fdb006849 624 Gene3D G3DSA:3.30.565.10 29 222 8.1E-54 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12375 08b7839adb353912d356a28fdb006849 624 SUPERFAMILY SSF110942 510 623 3.4E-35 T 28-03-2018 WM46_RS12375 08b7839adb353912d356a28fdb006849 624 SUPERFAMILY SSF54211 230 485 5.84E-102 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS12375 08b7839adb353912d356a28fdb006849 624 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 182 1.1E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 75 92 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 120 142 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 26 48 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 190 208 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 172 189 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 5 25 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 PRINTS PR00775 90kDa heat shock protein signature 93 110 1.2E-63 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal WM46_RS12375 08b7839adb353912d356a28fdb006849 624 SUPERFAMILY SSF55874 4 214 4.98E-67 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS12375 08b7839adb353912d356a28fdb006849 624 SMART SM00387 27 184 2.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS01180 bcae5c4a8b2f0dec472b2bd79ea7abc6 277 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 27 272 2.8E-107 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 WM46_RS01180 bcae5c4a8b2f0dec472b2bd79ea7abc6 277 TIGRFAM TIGR01699 XAPA: xanthosine phosphorylase 27 274 1.4E-152 T 28-03-2018 IPR010943 Xanthosine phosphorylase GO:0004731|GO:0005737|GO:0055086 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 WM46_RS01180 bcae5c4a8b2f0dec472b2bd79ea7abc6 277 Gene3D G3DSA:3.40.50.1580 7 276 3.8E-57 T 28-03-2018 WM46_RS01180 bcae5c4a8b2f0dec472b2bd79ea7abc6 277 Pfam PF01048 Phosphorylase superfamily 28 273 7.1E-43 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS01180 bcae5c4a8b2f0dec472b2bd79ea7abc6 277 SUPERFAMILY SSF53167 9 276 2.09E-84 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS01180 bcae5c4a8b2f0dec472b2bd79ea7abc6 277 PIRSF PIRSF000477 1 276 1.2E-113 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 WM46_RS06125 0f8509a3420f2697b618806823bc0a7f 242 SUPERFAMILY SSF53187 134 216 3.97E-32 T 28-03-2018 WM46_RS06125 0f8509a3420f2697b618806823bc0a7f 242 SUPERFAMILY SSF53187 18 107 3.97E-32 T 28-03-2018 WM46_RS06125 0f8509a3420f2697b618806823bc0a7f 242 Gene3D G3DSA:3.40.630.10 38 235 5.8E-28 T 28-03-2018 WM46_RS06125 0f8509a3420f2697b618806823bc0a7f 242 Pfam PF00246 Zinc carboxypeptidase 42 157 1.8E-12 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 Gene3D G3DSA:1.10.10.10 2 85 2.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 3.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 Pfam PF03466 LysR substrate binding domain 89 292 1.3E-42 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 Gene3D G3DSA:3.40.190.10 179 262 8.1E-21 T 28-03-2018 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 SUPERFAMILY SSF46785 6 113 1.03E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 Gene3D G3DSA:3.40.190.10 93 178 9.2E-17 T 28-03-2018 WM46_RS13780 04f9210738f7533025cb9fee0a096c1f 304 SUPERFAMILY SSF53850 90 296 5.79E-45 T 28-03-2018 WM46_RS03495 6e0de79fcb292bd765ba6bfdaf94e226 116 PIRSF PIRSF011503 1 114 6.8E-45 T 28-03-2018 IPR009192 Diol/glycerol dehydratase reactivating factor, small subunit WM46_RS03495 6e0de79fcb292bd765ba6bfdaf94e226 116 Pfam PF02288 Dehydratase medium subunit 8 111 3.4E-32 T 28-03-2018 IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor WM46_RS03495 6e0de79fcb292bd765ba6bfdaf94e226 116 Gene3D G3DSA:3.40.50.10150 5 115 4.8E-41 T 28-03-2018 IPR010254 B12-dependent dehydratases, beta subunit WM46_RS03495 6e0de79fcb292bd765ba6bfdaf94e226 116 SUPERFAMILY SSF52968 4 114 1.96E-37 T 28-03-2018 IPR010254 B12-dependent dehydratases, beta subunit WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 SUPERFAMILY SSF51419 9 233 1.01E-65 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 Pfam PF01168 Alanine racemase, N-terminal domain 9 217 6.5E-68 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 SMART SM01005 232 356 2.0E-60 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 Gene3D G3DSA:2.40.37.10 202 356 1.1E-60 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 190 217 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 338 351 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 27 43 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 155 166 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 286 303 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 121 133 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 248 263 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 265 280 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 PRINTS PR00992 Alanine racemase signature 61 79 6.0E-75 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 Gene3D G3DSA:3.20.20.10 7 201 2.3E-39 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 TIGRFAM TIGR00492 alr: alanine racemase 4 356 1.3E-136 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 SUPERFAMILY SSF50621 227 355 3.84E-44 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 Hamap MF_01201 Alanine racemase. 2 356 33.588 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS05180 9044c44380bda098cccab64e83d704ea 356 Pfam PF00842 Alanine racemase, C-terminal domain 232 354 3.0E-40 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS14190 e4823789ecf75a703153e886852168aa 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS14190 e4823789ecf75a703153e886852168aa 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 2.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS14190 e4823789ecf75a703153e886852168aa 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 2.4E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS14190 e4823789ecf75a703153e886852168aa 251 SUPERFAMILY SSF53474 9 250 1.99E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS14190 e4823789ecf75a703153e886852168aa 251 Gene3D G3DSA:3.40.50.1820 5 251 4.9E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS14190 e4823789ecf75a703153e886852168aa 251 Pfam PF12697 Alpha/beta hydrolase family 25 243 1.7E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 SUPERFAMILY SSF55347 131 319 4.37E-51 T 28-03-2018 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 PIRSF PIRSF000148 4 337 4.0E-99 T 28-03-2018 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 SUPERFAMILY SSF51735 5 157 1.08E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 Gene3D G3DSA:3.40.50.720 1 143 1.7E-29 T 28-03-2018 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 Gene3D G3DSA:3.30.360.10 144 314 5.1E-45 T 28-03-2018 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 317 1.4E-39 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 118 7.5E-24 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS01565 bd3eff9b4b0c09ddcea8d28ca6af8bee 337 SMART SM00859 6 121 3.2E-31 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 Gene3D G3DSA:3.20.20.70 1 316 2.2E-118 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 SUPERFAMILY SSF51569 1 315 1.05E-113 T 28-03-2018 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 TIGRFAM TIGR00874 talAB: transaldolase 2 316 1.8E-163 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 Hamap MF_00492 Transaldolase [tal]. 1 316 52.733 T 28-03-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 310 8.6E-103 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS00935 c65f519c50b0b1a838f2fe9cf4c8332f 316 ProSitePatterns PS00958 Transaldolase active site. 128 145 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 WM46_RS21440 4e17e1ced56db9afb4bcab53b0c5dcb5 90 ProDom PD063639 YJBD CYTOPLASMIC STY4411 YPO2363 ECS5006 Y1969 3 90 2.0E-31 T 28-03-2018 IPR020317 Uncharacterised protein family YjbD WM46_RS21440 4e17e1ced56db9afb4bcab53b0c5dcb5 90 Pfam PF11656 YjbD family (DUF3811) 3 90 1.3E-37 T 28-03-2018 IPR020317 Uncharacterised protein family YjbD WM46_RS23330 82c39ddb3d09b1c4abf4ec9dc8fc13e2 491 PIRSF PIRSF006060 413 490 6.9 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS23330 82c39ddb3d09b1c4abf4ec9dc8fc13e2 491 PIRSF PIRSF006060 5 452 2.9E-41 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS23330 82c39ddb3d09b1c4abf4ec9dc8fc13e2 491 Pfam PF13520 Amino acid permease 23 451 2.5E-71 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS23330 82c39ddb3d09b1c4abf4ec9dc8fc13e2 491 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 17 490 2.2E-166 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 WM46_RS23330 82c39ddb3d09b1c4abf4ec9dc8fc13e2 491 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 21 489 2.3E-183 T 28-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 WM46_RS26060 04b1bc7082dfc2da14c9fc654a0eb610 439 Pfam PF13751 Transposase DDE domain 364 436 4.0E-16 T 28-03-2018 IPR025668 Transposase DDE domain WM46_RS26060 04b1bc7082dfc2da14c9fc654a0eb610 439 Pfam PF05598 Transposase domain (DUF772) 55 124 2.8E-13 T 28-03-2018 IPR008490 Transposase InsH, N-terminal WM46_RS23550 d4c6530f710101b61013fc80208ba522 293 SUPERFAMILY SSF74650 10 272 2.43E-57 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS23550 d4c6530f710101b61013fc80208ba522 293 Pfam PF01263 Aldose 1-epimerase 31 275 7.5E-31 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 WM46_RS23550 d4c6530f710101b61013fc80208ba522 293 PIRSF PIRSF016020 9 287 2.8E-41 T 28-03-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 WM46_RS23550 d4c6530f710101b61013fc80208ba522 293 Gene3D G3DSA:2.70.98.10 2 291 5.2E-47 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 Pfam PF00361 Proton-conducting membrane transporter 134 430 2.6E-68 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 499 4.3E-183 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 337 356 2.9E-37 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 2.9E-37 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 389 415 2.9E-37 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 139 158 2.9E-37 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01815 df5080e57c481d8b799f807bac7eef70 509 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 2.9E-37 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS23215 d30c77f17d14ddd33c3826da07947296 258 Pfam PF14188 Domain of unknown function (DUF4311) 25 237 7.5E-124 T 28-03-2018 IPR020042 Protein of unknown function DUF4311 WM46_RS23215 d30c77f17d14ddd33c3826da07947296 258 TIGRFAM TIGR03580 EF_0832: conserved hypothetical protein EF_0832/AHA_3913 2 258 5.1E-158 T 28-03-2018 IPR020042 Protein of unknown function DUF4311 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 Pfam PF03099 Biotin/lipoate A/B protein ligase family 62 159 9.0E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 SUPERFAMILY SSF55681 5 204 5.05E-68 T 28-03-2018 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 204 6.8E-82 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 8.0E-23 T 28-03-2018 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 PIRSF PIRSF016262 1 209 3.7E-58 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 Hamap MF_00013 Octanoyltransferase [lipB]. 5 206 37.445 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 WM46_RS11415 0a54d85d48d63855d805a354ab3dbbc5 213 Gene3D G3DSA:3.30.930.10 1 204 9.5E-61 T 28-03-2018 WM46_RS04250 98df658884543b7b6636b38355056b43 248 Hamap MF_00795 Copper homeostasis protein CutC [cutC]. 2 243 38.193 T 28-03-2018 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 Reactome: R-HSA-936837 WM46_RS04250 98df658884543b7b6636b38355056b43 248 Pfam PF03932 CutC family 3 200 1.1E-82 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 WM46_RS04250 98df658884543b7b6636b38355056b43 248 Gene3D G3DSA:3.20.20.380 1 248 6.3E-93 T 28-03-2018 WM46_RS04250 98df658884543b7b6636b38355056b43 248 SUPERFAMILY SSF110395 3 242 6.93E-77 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 WM46_RS01665 7323538b4d8d54871042edc5c0cd783e 214 Pfam PF14834 Glutathione S-transferase, C-terminal domain 95 211 8.2E-65 T 28-03-2018 IPR034338 Glutathione S-transferases, subfamily 4, C-terminal KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 WM46_RS01665 7323538b4d8d54871042edc5c0cd783e 214 Pfam PF02798 Glutathione S-transferase, N-terminal domain 14 80 6.0E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS01665 7323538b4d8d54871042edc5c0cd783e 214 SUPERFAMILY SSF47616 90 207 4.77E-8 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS01665 7323538b4d8d54871042edc5c0cd783e 214 Gene3D G3DSA:3.40.30.10 1 104 7.5E-23 T 28-03-2018 WM46_RS01665 7323538b4d8d54871042edc5c0cd783e 214 SUPERFAMILY SSF52833 14 87 1.64E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS01665 7323538b4d8d54871042edc5c0cd783e 214 Gene3D G3DSA:1.20.1050.10 105 207 5.9E-12 T 28-03-2018 WM46_RS16690 1ff626dd324d0ca0f54fad6401336c50 172 Pfam PF01965 DJ-1/PfpI family 3 167 6.7E-55 T 28-03-2018 IPR002818 DJ-1/PfpI WM46_RS16690 1ff626dd324d0ca0f54fad6401336c50 172 Gene3D G3DSA:3.40.50.880 1 171 5.0E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS16690 1ff626dd324d0ca0f54fad6401336c50 172 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 1.1E-69 T 28-03-2018 IPR006286 Peptidase C56, PfpI WM46_RS16690 1ff626dd324d0ca0f54fad6401336c50 172 SUPERFAMILY SSF52317 3 170 5.84E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 SUPERFAMILY SSF54862 1 191 4.19E-62 T 28-03-2018 WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 Gene3D G3DSA:3.30.70.20 81 115 2.1E-19 T 28-03-2018 WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 Gene3D G3DSA:3.30.70.20 2 80 4.9E-20 T 28-03-2018 WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 Pfam PF13247 4Fe-4S dicluster domain 59 153 2.2E-28 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 TIGRFAM TIGR02951 DMSO_dmsB: dimethylsulfoxide reductase, chain B 3 163 1.6E-84 T 28-03-2018 IPR014297 Dimethylsulphoxide reductase, chain B WM46_RS22020 d2dec63bbbf4386dbb21f7575601c973 208 Gene3D G3DSA:3.30.70.20 116 195 1.8E-13 T 28-03-2018 WM46_RS06245 7c9ebcb5068ae0ebae70a86c86bc5f32 74 Pfam PF00589 Phage integrase family 5 54 2.7E-5 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS06245 7c9ebcb5068ae0ebae70a86c86bc5f32 74 Gene3D G3DSA:1.10.443.10 3 57 1.1E-7 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS06245 7c9ebcb5068ae0ebae70a86c86bc5f32 74 SUPERFAMILY SSF56349 7 53 3.53E-9 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS10045 3e40541e18d5acf29d1f14c4fbaf9804 552 SUPERFAMILY SSF52540 1 91 3.42E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10045 3e40541e18d5acf29d1f14c4fbaf9804 552 SUPERFAMILY SSF52540 163 341 3.42E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10045 3e40541e18d5acf29d1f14c4fbaf9804 552 Gene3D G3DSA:3.40.50.300 1 348 3.9E-18 T 28-03-2018 WM46_RS10045 3e40541e18d5acf29d1f14c4fbaf9804 552 Pfam PF11398 Protein of unknown function (DUF2813) 1 375 9.0E-154 T 28-03-2018 IPR022602 Protein of unknown function DUF2813 WM46_RS15395 7fef8db8c4710c5394c0e025d5a46bdc 332 Pfam PF16344 Domain of unknown function (DUF4974) 221 309 8.7E-9 T 28-03-2018 IPR032508 Protein FecR, C-terminal WM46_RS15395 7fef8db8c4710c5394c0e025d5a46bdc 332 PIRSF PIRSF018266 7 323 1.0E-74 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component WM46_RS15395 7fef8db8c4710c5394c0e025d5a46bdc 332 Pfam PF04773 FecR protein 118 208 7.5E-22 T 28-03-2018 IPR006860 FecR protein WM46_RS15395 7fef8db8c4710c5394c0e025d5a46bdc 332 Pfam PF16220 Domain of unknown function (DUF4880) 18 52 3.0E-11 T 28-03-2018 IPR032623 FecR, N-terminal WM46_RS17165 16b428fefecd08a25d8da77e5117179f 342 PIRSF PIRSF038471 2 284 3.6E-75 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 WM46_RS17165 16b428fefecd08a25d8da77e5117179f 342 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 284 3.2E-126 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 WM46_RS17165 16b428fefecd08a25d8da77e5117179f 342 Pfam PF04085 rod shape-determining protein MreC 123 269 4.5E-36 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Gene3D G3DSA:3.30.950.10 341 457 7.3E-39 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Gene3D G3DSA:3.30.160.110 121 148 1.2E-16 T 28-03-2018 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Gene3D G3DSA:3.40.1010.10 215 340 2.2E-35 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 296 329 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 5.6E-70 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 221 235 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Pfam PF10414 Sirohaem synthase dimerisation region 150 208 8.0E-19 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 1.3E-8 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 PIRSF PIRSF036426 1 457 5.5E-204 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Hamap MF_01646 Siroheme synthase [cysG]. 1 457 50.958 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Gene3D G3DSA:1.10.8.210 151 209 2.5E-19 T 28-03-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 216 448 1.4E-91 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 SUPERFAMILY SSF75615 114 208 1.11E-26 T 28-03-2018 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 218 426 2.8E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 SUPERFAMILY SSF51735 2 112 4.23E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Pfam PF13241 Putative NAD(P)-binding 6 115 7.6E-25 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 SUPERFAMILY SSF53790 215 456 1.7E-78 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS17740 12d90166d42a2da47e128815c76a1ecd 457 Gene3D G3DSA:3.40.50.720 3 120 2.0E-19 T 28-03-2018 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 SUPERFAMILY SSF55781 2 159 7.85E-30 T 28-03-2018 IPR029016 GAF domain-like WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 SUPERFAMILY SSF47831 197 309 8.5E-26 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 SMART SM00065 17 164 7.7E-29 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 SUPERFAMILY SSF52009 293 412 2.49E-24 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 175 729 1.7E-124 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 SUPERFAMILY SSF51621 419 715 1.28E-96 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Pfam PF05524 PEP-utilising enzyme, N-terminal 174 294 5.1E-23 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Gene3D G3DSA:3.20.20.60 420 739 4.6E-86 T 28-03-2018 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Gene3D G3DSA:1.10.274.10 195 303 4.0E-28 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 420 707 4.1E-107 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 613 631 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Pfam PF01590 GAF domain 18 152 6.5E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Gene3D G3DSA:3.50.30.10 304 419 2.5E-18 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Pfam PF00391 PEP-utilising enzyme, mobile domain 320 391 3.3E-15 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 Gene3D G3DSA:3.30.450.40 1 173 1.1E-28 T 28-03-2018 IPR029016 GAF domain-like WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 351 362 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 666 678 2.1E-24 T 28-03-2018 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 459 478 2.1E-24 T 28-03-2018 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 630 645 2.1E-24 T 28-03-2018 WM46_RS24865 85a1be6000dcf07c377bfb40d631702a 748 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 613 628 2.1E-24 T 28-03-2018 WM46_RS12550 795d9f54fd353f575287fbdca41beb20 287 Gene3D G3DSA:3.10.129.10 2 116 2.3E-44 T 28-03-2018 WM46_RS12550 795d9f54fd353f575287fbdca41beb20 287 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 283 8.6E-103 T 28-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 WM46_RS12550 795d9f54fd353f575287fbdca41beb20 287 Pfam PF13622 Thioesterase-like superfamily 33 282 1.1E-57 T 28-03-2018 WM46_RS12550 795d9f54fd353f575287fbdca41beb20 287 Gene3D G3DSA:3.10.129.10 131 286 6.5E-53 T 28-03-2018 WM46_RS12550 795d9f54fd353f575287fbdca41beb20 287 SUPERFAMILY SSF54637 116 284 2.33E-58 T 28-03-2018 IPR029069 HotDog domain WM46_RS12550 795d9f54fd353f575287fbdca41beb20 287 SUPERFAMILY SSF54637 5 114 1.41E-42 T 28-03-2018 IPR029069 HotDog domain WM46_RS10275 a0e1e937cb720e1635f4a9a687c3585a 306 SUPERFAMILY SSF161098 90 288 7.98E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10275 a0e1e937cb720e1635f4a9a687c3585a 306 Gene3D G3DSA:1.10.3720.10 2 293 1.1E-45 T 28-03-2018 WM46_RS10275 a0e1e937cb720e1635f4a9a687c3585a 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 2.9E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 SUPERFAMILY SSF63520 292 391 1.1E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 SUPERFAMILY SSF55804 490 628 1.45E-25 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Gene3D G3DSA:1.10.1790.10 189 278 1.4E-5 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Pfam PF05043 Mga helix-turn-helix domain 88 165 4.9E-13 T 28-03-2018 IPR007737 Mga helix-turn-helix domain WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Gene3D G3DSA:1.10.1790.10 279 392 4.7E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 539 555 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Gene3D G3DSA:3.40.930.10 490 631 7.2E-22 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Gene3D G3DSA:3.40.50.2300 398 483 2.2E-12 T 28-03-2018 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 509 627 5.1E-17 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 SUPERFAMILY SSF52794 401 478 2.04E-5 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Pfam PF08279 HTH domain 7 63 1.7E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Gene3D G3DSA:1.10.10.10 86 153 1.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Gene3D G3DSA:1.10.10.10 3 68 2.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23240 7e9bd0446c598f39e43cdf5eed65845b 636 Pfam PF00874 PRD domain 300 386 5.2E-19 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS17695 11434471c8325edaa52af939e978878d 405 PIRSF PIRSF000521 174 403 1.4E-36 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS17695 11434471c8325edaa52af939e978878d 405 PIRSF PIRSF000521 28 156 5.3E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS17695 11434471c8325edaa52af939e978878d 405 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 400 1.3E-150 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 WM46_RS17695 11434471c8325edaa52af939e978878d 405 Gene3D G3DSA:3.40.640.10 60 289 9.0E-75 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS17695 11434471c8325edaa52af939e978878d 405 Pfam PF00202 Aminotransferase class-III 26 400 1.6E-139 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS17695 11434471c8325edaa52af939e978878d 405 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 8 404 9.7E-205 T 28-03-2018 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 WM46_RS17695 11434471c8325edaa52af939e978878d 405 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 14 401 45.335 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 WM46_RS17695 11434471c8325edaa52af939e978878d 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS17695 11434471c8325edaa52af939e978878d 405 SUPERFAMILY SSF53383 19 400 1.63E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS17695 11434471c8325edaa52af939e978878d 405 Gene3D G3DSA:3.90.1150.10 290 405 1.0E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS10580 d9fff3a3fb7949bf80361e3db58d9025 251 SUPERFAMILY SSF53335 10 178 5.16E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS10580 d9fff3a3fb7949bf80361e3db58d9025 251 Pfam PF08241 Methyltransferase domain 47 138 4.1E-25 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 WM46_RS10580 d9fff3a3fb7949bf80361e3db58d9025 251 Gene3D G3DSA:3.40.50.150 4 220 2.4E-37 T 28-03-2018 WM46_RS10580 d9fff3a3fb7949bf80361e3db58d9025 251 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 12 249 2.5E-69 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 WM46_RS10580 d9fff3a3fb7949bf80361e3db58d9025 251 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 4 250 29.809 T 28-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 Pfam PF03466 LysR substrate binding domain 112 289 7.1E-18 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 Gene3D G3DSA:3.40.190.10 94 183 2.8E-6 T 28-03-2018 WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 SUPERFAMILY SSF46785 8 91 1.69E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 SUPERFAMILY SSF53850 93 290 1.71E-22 T 28-03-2018 WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 5.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 Gene3D G3DSA:1.10.10.10 2 89 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16460 8af79d4485e929cb5ba48f8be4873aa9 298 Gene3D G3DSA:3.40.190.10 184 268 1.1E-10 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Pfam PF08335 GlnD PII-uridylyltransferase 193 331 1.4E-36 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Pfam PF01966 HD domain 468 601 6.8E-15 T 28-03-2018 IPR006674 HD domain WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Gene3D G3DSA:3.30.70.260 701 784 7.4E-9 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Gene3D G3DSA:3.30.460.10 52 186 1.3E-23 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 SUPERFAMILY SSF55021 705 763 6.25E-9 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Gene3D G3DSA:1.10.3090.10 363 655 2.7E-36 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 890 348.9 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 SMART SM00471 464 611 2.5E-11 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Pfam PF01909 Nucleotidyltransferase domain 86 143 1.3E-6 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 SUPERFAMILY SSF109604 457 600 6.91E-14 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 SUPERFAMILY SSF81301 20 189 3.87E-21 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 SUPERFAMILY SSF55021 815 873 1.53E-9 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 51 884 2.7E-299 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Pfam PF01842 ACT domain 709 759 4.4E-7 T 28-03-2018 IPR002912 ACT domain WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Pfam PF01842 ACT domain 817 873 3.9E-9 T 28-03-2018 IPR002912 ACT domain WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Gene3D G3DSA:1.20.120.330 190 334 2.0E-25 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 PIRSF PIRSF006288 22 889 0.0 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 SUPERFAMILY SSF81593 207 328 5.89E-10 T 28-03-2018 WM46_RS13990 f2fe0f88da2c39c6113c57cb6ab0a92f 890 Gene3D G3DSA:3.30.70.260 809 885 9.0E-11 T 28-03-2018 WM46_RS23810 f2fafe6de890d9f9ea648d3ffbac1678 410 Pfam PF07690 Major Facilitator Superfamily 23 357 1.3E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS23810 f2fafe6de890d9f9ea648d3ffbac1678 410 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 85 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS23810 f2fafe6de890d9f9ea648d3ffbac1678 410 SUPERFAMILY SSF103473 14 393 6.8E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS23810 f2fafe6de890d9f9ea648d3ffbac1678 410 Gene3D G3DSA:1.20.1250.20 205 406 5.0E-12 T 28-03-2018 WM46_RS23810 f2fafe6de890d9f9ea648d3ffbac1678 410 Gene3D G3DSA:1.20.1250.20 3 197 5.8E-27 T 28-03-2018 WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 Gene3D G3DSA:3.90.1150.10 271 385 1.5E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 3 384 49.354 T 28-03-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 20 381 4.9E-144 T 28-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 Pfam PF00155 Aminotransferase class I and II 41 380 2.3E-63 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 SUPERFAMILY SSF53383 3 381 6.92E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS10585 d493d0958300be8207a18bf1c6fb7417 385 Gene3D G3DSA:3.40.640.10 57 270 1.3E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS25285 a96957eaf722719242d0a6fb413a1c5a 208 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 2 207 7.7E-98 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM46_RS25285 a96957eaf722719242d0a6fb413a1c5a 208 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 6 206 7.5E-81 T 28-03-2018 WM46_RS25285 a96957eaf722719242d0a6fb413a1c5a 208 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 208 39.067 T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM46_RS25285 a96957eaf722719242d0a6fb413a1c5a 208 Gene3D G3DSA:3.40.50.150 2 206 5.5E-37 T 28-03-2018 WM46_RS25285 a96957eaf722719242d0a6fb413a1c5a 208 SUPERFAMILY SSF53335 11 204 1.27E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS25285 a96957eaf722719242d0a6fb413a1c5a 208 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 130 145 - T 28-03-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 WM46_RS18095 12316474aea6a2d8363a61cea33e999b 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 276 4.1E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS18095 12316474aea6a2d8363a61cea33e999b 281 SUPERFAMILY SSF161098 4 277 3.92E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS18095 12316474aea6a2d8363a61cea33e999b 281 Gene3D G3DSA:1.10.3720.10 3 270 2.7E-30 T 28-03-2018 WM46_RS01490 58d50bd1c8f8f0989f0c977e5a5d437e 161 SUPERFAMILY SSF53254 1 145 1.03E-17 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS01490 58d50bd1c8f8f0989f0c977e5a5d437e 161 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 70 3.6E-6 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS01490 58d50bd1c8f8f0989f0c977e5a5d437e 161 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 152 2.5E-58 T 28-03-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 WM46_RS01490 58d50bd1c8f8f0989f0c977e5a5d437e 161 Gene3D G3DSA:3.40.50.1240 1 161 2.5E-19 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS25300 71511fb1275b365adebda233b2911d89 135 SUPERFAMILY SSF46785 3 133 2.49E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25300 71511fb1275b365adebda233b2911d89 135 SMART SM00347 24 122 1.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25300 71511fb1275b365adebda233b2911d89 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 3.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25300 71511fb1275b365adebda233b2911d89 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 3.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25300 71511fb1275b365adebda233b2911d89 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 3.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25300 71511fb1275b365adebda233b2911d89 135 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 3.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25300 71511fb1275b365adebda233b2911d89 135 Gene3D G3DSA:1.10.10.10 1 133 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25300 71511fb1275b365adebda233b2911d89 135 ProSitePatterns PS01117 MarR-type HTH domain signature. 61 95 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site WM46_RS25300 71511fb1275b365adebda233b2911d89 135 Pfam PF01047 MarR family 29 85 7.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25535 fc4f077eb268a92f29017fcaaedd8fa3 61 Pfam PF02599 Global regulator protein family 1 52 2.5E-27 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 WM46_RS25535 fc4f077eb268a92f29017fcaaedd8fa3 61 Hamap MF_00167 Carbon storage regulator [csrA]. 1 61 20.514 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 WM46_RS25535 fc4f077eb268a92f29017fcaaedd8fa3 61 SUPERFAMILY SSF117130 1 54 3.66E-21 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 WM46_RS25535 fc4f077eb268a92f29017fcaaedd8fa3 61 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 2.0E-31 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 WM46_RS25535 fc4f077eb268a92f29017fcaaedd8fa3 61 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-20 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 Pfam PF13411 MerR HTH family regulatory protein 2 69 2.2E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 SUPERFAMILY SSF46955 2 121 4.4E-34 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 SMART SM00422 2 71 2.6E-30 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 Gene3D G3DSA:1.10.1660.10 1 57 1.1E-22 T 28-03-2018 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 TIGRFAM TIGR02043 ZntR: Zn(II)-responsive transcriptional regulator 1 131 3.4E-62 T 28-03-2018 IPR011788 Zn(II)-responsive transcriptional regulator GO:0003677|GO:0006351|GO:0008270 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 3.9E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 3.9E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 3.9E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS17405 40f26233e3fe249e4937095d7f5c014f 141 Gene3D G3DSA:1.10.1660.10 58 141 1.5E-24 T 28-03-2018 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 SUPERFAMILY SSF54373 180 283 4.71E-23 T 28-03-2018 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 Pfam PF01494 FAD binding domain 7 189 2.0E-9 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 7.0E-8 T 28-03-2018 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 7.0E-8 T 28-03-2018 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 7.0E-8 T 28-03-2018 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 Gene3D G3DSA:3.50.50.60 2 363 3.8E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 SUPERFAMILY SSF51905 4 180 3.5E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS14615 4d919c5302aefc6671b19998cfa7b42f 428 SUPERFAMILY SSF51905 283 391 3.5E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 SUPERFAMILY SSF46689 228 276 2.69E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 Gene3D G3DSA:2.60.120.10 6 233 7.5E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 SUPERFAMILY SSF46689 180 225 1.34E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 Pfam PF12833 Helix-turn-helix domain 198 276 6.0E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 SUPERFAMILY SSF51215 26 106 4.45E-16 T 28-03-2018 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 Gene3D G3DSA:1.10.10.60 234 278 8.8E-12 T 28-03-2018 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 SMART SM00342 192 275 3.7E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS24420 34d6c6697e7756c480eb33d26e332aae 281 Pfam PF02311 AraC-like ligand binding domain 20 105 6.4E-12 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS01240 37be2f1e51ff9cec0ba548db922f21ba 130 Gene3D G3DSA:1.10.10.10 1 21 0.0031 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01240 37be2f1e51ff9cec0ba548db922f21ba 130 Pfam PF07037 Putative transcription regulator (DUF1323) 8 129 1.2E-54 T 28-03-2018 IPR010749 Protein of unknown function DUF1323 WM46_RS01240 37be2f1e51ff9cec0ba548db922f21ba 130 SUPERFAMILY SSF46955 5 82 4.3E-13 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS01240 37be2f1e51ff9cec0ba548db922f21ba 130 ProDom PD060594 TRANSCRIPTION YFED YFEC DNA-BINDING REGULATION NEGATIVE REGULATOR STY2653 ECS3274 STY2652 8 129 7.0E-56 T 28-03-2018 IPR010749 Protein of unknown function DUF1323 WM46_RS01240 37be2f1e51ff9cec0ba548db922f21ba 130 Gene3D G3DSA:1.10.10.10 22 62 1.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 Gene3D G3DSA:3.30.1890.10 46 423 1.1E-68 T 28-03-2018 WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 SUPERFAMILY SSF52540 527 707 8.12E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 Pfam PF02706 Chain length determinant protein 16 107 1.7E-21 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 508 711 2.3E-46 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 Pfam PF13807 G-rich domain on putative tyrosine kinase 367 447 9.5E-31 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 Pfam PF13614 AAA domain 538 674 2.3E-12 T 28-03-2018 IPR025669 AAA domain WM46_RS02805 624cd8433cdf272953d0a916405851ee 720 Gene3D G3DSA:3.40.50.300 495 714 1.2E-31 T 28-03-2018 WM46_RS07535 22fb428e305c8e1846891b710e9abd65 298 SUPERFAMILY SSF51430 3 295 1.7E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS07535 22fb428e305c8e1846891b710e9abd65 298 Gene3D G3DSA:3.20.20.100 1 298 1.3E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS07535 22fb428e305c8e1846891b710e9abd65 298 PRINTS PR00069 Aldo-keto reductase signature 112 130 2.5E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS07535 22fb428e305c8e1846891b710e9abd65 298 PRINTS PR00069 Aldo-keto reductase signature 143 160 2.5E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS07535 22fb428e305c8e1846891b710e9abd65 298 Pfam PF00248 Aldo/keto reductase family 18 291 2.0E-59 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 SMART SM00448 2 112 1.0E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 Pfam PF00072 Response regulator receiver domain 4 112 2.7E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 7.5E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 SUPERFAMILY SSF52172 3 176 1.07E-38 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 Gene3D G3DSA:3.40.50.2300 1 119 2.3E-35 T 28-03-2018 WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 Gene3D G3DSA:1.10.10.10 120 225 9.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11115 40c534078280903da1a3b3c8ef174492 225 SMART SM00862 147 223 1.7E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS09055 0c235bda5b1e2b7b3fd071f366d58a88 242 Pfam PF11319 Type VI secretion system VasI, EvfG, VC_A0118 54 239 1.1E-53 T 28-03-2018 IPR017738 Type VI secretion system-associated, VCA0118 WM46_RS09055 0c235bda5b1e2b7b3fd071f366d58a88 242 TIGRFAM TIGR03360 VI_minor_1: type VI secretion-associated protein, VC_A0118 family 51 239 1.0E-72 T 28-03-2018 IPR017738 Type VI secretion system-associated, VCA0118 WM46_RS04930 e888dcf1254e0d94e030231577264b15 269 Gene3D G3DSA:3.40.50.150 1 269 2.1E-58 T 28-03-2018 WM46_RS04930 e888dcf1254e0d94e030231577264b15 269 SUPERFAMILY SSF53335 4 251 1.63E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04930 e888dcf1254e0d94e030231577264b15 269 Pfam PF13847 Methyltransferase domain 86 196 2.0E-13 T 28-03-2018 IPR025714 Methyltransferase domain WM46_RS04930 e888dcf1254e0d94e030231577264b15 269 PIRSF PIRSF018249 1 268 2.5E-91 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 WM46_RS02035 155af0c738d46964c7bab1d26920da1b 251 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 74 1.1E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS02035 155af0c738d46964c7bab1d26920da1b 251 SUPERFAMILY SSF46689 1 76 4.84E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS02035 155af0c738d46964c7bab1d26920da1b 251 Gene3D G3DSA:1.10.10.10 1 141 6.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 609 41.584 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Gene3D G3DSA:3.40.50.10490 240 457 1.6E-59 T 28-03-2018 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Gene3D G3DSA:3.40.50.10490 458 607 4.0E-52 T 28-03-2018 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Gene3D G3DSA:3.60.20.10 2 239 3.6E-69 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Pfam PF01380 SIS domain 462 591 8.2E-31 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Pfam PF01380 SIS domain 289 418 2.8E-34 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 SUPERFAMILY SSF56235 2 232 1.97E-75 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 Pfam PF13522 Glutamine amidotransferase domain 65 182 1.2E-21 T 28-03-2018 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 SUPERFAMILY SSF53697 245 609 5.1E-115 T 28-03-2018 WM46_RS19540 88365c93d28f8e26fe306a97c1dbb012 609 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 609 1.2E-270 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 WM46_RS05855 b7b5cd6a6fee662e3f88340935cde0ca 293 SUPERFAMILY SSF89550 172 286 9.03E-52 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM46_RS05855 b7b5cd6a6fee662e3f88340935cde0ca 293 SUPERFAMILY SSF89550 9 90 9.03E-52 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 WM46_RS05855 b7b5cd6a6fee662e3f88340935cde0ca 293 Gene3D G3DSA:3.20.20.140 9 265 4.4E-39 T 28-03-2018 WM46_RS05855 b7b5cd6a6fee662e3f88340935cde0ca 293 Pfam PF02811 PHP domain 11 129 2.6E-8 T 28-03-2018 IPR004013 PHP domain GO:0003824 WM46_RS05855 b7b5cd6a6fee662e3f88340935cde0ca 293 SMART SM00481 10 77 1.1E-18 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 SUPERFAMILY SSF46689 222 271 4.93E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 Gene3D G3DSA:1.10.10.60 186 228 2.7E-10 T 28-03-2018 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 SUPERFAMILY SSF46689 170 219 7.17E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 SUPERFAMILY SSF51215 32 141 6.15E-17 T 28-03-2018 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 Pfam PF02311 AraC-like ligand binding domain 24 137 4.4E-22 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 SMART SM00342 186 268 1.1E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 Gene3D G3DSA:1.10.10.60 229 274 4.9E-10 T 28-03-2018 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 Pfam PF12833 Helix-turn-helix domain 192 269 9.0E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS23040 55cf77b8a455d18091289e3e6c36c95d 274 Gene3D G3DSA:2.60.120.280 10 185 1.6E-13 T 28-03-2018 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 448 462 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 PRINTS PR00132 Glycosyl hydrolase family 2 signature 147 162 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 PRINTS PR00132 Glycosyl hydrolase family 2 signature 376 394 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 PRINTS PR00132 Glycosyl hydrolase family 2 signature 448 463 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 PRINTS PR00132 Glycosyl hydrolase family 2 signature 345 359 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 PRINTS PR00132 Glycosyl hydrolase family 2 signature 532 547 3.2E-38 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Hamap MF_01687 Beta-galactosidase [lacZ]. 6 1027 17.461 T 28-03-2018 IPR023933 Glycoside hydrolase, family 2, beta-galactosidase GO:0016798 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Pfam PF02929 Beta galactosidase small chain 758 1023 1.4E-61 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Pfam PF16353 Domain of unknown function(DUF4981) 640 726 1.0E-19 T 28-03-2018 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 SUPERFAMILY SSF49303 622 729 6.12E-31 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 SUPERFAMILY SSF51445 337 625 8.62E-103 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 SUPERFAMILY SSF49303 221 334 1.99E-25 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Gene3D G3DSA:2.60.40.10 220 334 6.1E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 337 629 1.9E-121 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 SUPERFAMILY SSF74650 739 1024 2.2E-93 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Pfam PF00703 Glycosyl hydrolases family 2 222 334 5.3E-14 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Gene3D G3DSA:2.70.98.10 736 1027 3.6E-78 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 SMART SM01038 752 1025 4.8E-119 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Gene3D G3DSA:2.60.120.260 3 219 2.9E-65 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 53 219 9.0E-64 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Gene3D G3DSA:3.20.20.80 335 625 3.6E-86 T 28-03-2018 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 386 411 - T 28-03-2018 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 Gene3D G3DSA:2.60.40.10 626 734 1.6E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS13145 0b0fee037387e8a4bee0fdd9fa9b4b3f 1027 SUPERFAMILY SSF49785 15 218 9.78E-66 T 28-03-2018 IPR008979 Galactose-binding domain-like WM46_RS10600 5b929e1b336bf0a010de527902ed1527 158 Gene3D G3DSA:3.90.280.10 1 158 8.4E-52 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein WM46_RS10600 5b929e1b336bf0a010de527902ed1527 158 Pfam PF01161 Phosphatidylethanolamine-binding protein 14 157 2.3E-38 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein WM46_RS10600 5b929e1b336bf0a010de527902ed1527 158 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 18 157 2.9E-56 T 28-03-2018 IPR005247 YbhB/YbcL WM46_RS10600 5b929e1b336bf0a010de527902ed1527 158 SUPERFAMILY SSF49777 1 157 4.45E-53 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein WM46_RS23910 0b9d1d95bb8025b2e1d83750535a9697 335 Gene3D G3DSA:1.10.1530.10 4 79 1.7E-21 T 28-03-2018 WM46_RS23910 0b9d1d95bb8025b2e1d83750535a9697 335 SUPERFAMILY SSF89733 5 334 1.96E-99 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 WM46_RS23910 0b9d1d95bb8025b2e1d83750535a9697 335 Pfam PF02615 Malate/L-lactate dehydrogenase 8 331 7.0E-100 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 WM46_RS23910 0b9d1d95bb8025b2e1d83750535a9697 335 Gene3D G3DSA:1.10.1530.10 295 325 2.9E-4 T 28-03-2018 WM46_RS23910 0b9d1d95bb8025b2e1d83750535a9697 335 Gene3D G3DSA:3.30.1370.60 80 294 6.9E-80 T 28-03-2018 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 45.176 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 Pfam PF00920 Dehydratase family 34 607 1.6E-218 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 4.0E-271 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 Gene3D G3DSA:3.40.50.2300 54 173 0.0064 T 28-03-2018 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 SUPERFAMILY SSF143975 3 420 2.48E-134 T 28-03-2018 WM46_RS19330 f9fe5e0b900f36a85e42bd269098486c 616 SUPERFAMILY SSF52016 421 610 1.26E-59 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS11235 853f97dfd74ee861b8561d18667aca79 250 Gene3D G3DSA:3.40.50.1000 1 249 2.3E-28 T 28-03-2018 IPR023214 HAD-like domain WM46_RS11235 853f97dfd74ee861b8561d18667aca79 250 Pfam PF13242 HAD-hyrolase-like 174 246 1.1E-19 T 28-03-2018 WM46_RS11235 853f97dfd74ee861b8561d18667aca79 250 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 4.6E-22 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA WM46_RS11235 853f97dfd74ee861b8561d18667aca79 250 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 223 1.3E-64 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA WM46_RS11235 853f97dfd74ee861b8561d18667aca79 250 SUPERFAMILY SSF56784 1 247 2.58E-64 T 28-03-2018 IPR023214 HAD-like domain WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 Gene3D G3DSA:3.30.420.40 2 186 1.3E-34 T 28-03-2018 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 SMART SM00842 10 196 3.0E-96 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 420 29.547 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 2.6E-161 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 5.3E-30 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 Pfam PF14450 Cell division protein FtsA 207 381 8.9E-25 T 28-03-2018 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 Gene3D G3DSA:3.90.640.10 248 300 3.9E-19 T 28-03-2018 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 Gene3D G3DSA:3.30.420.40 197 247 1.8E-6 T 28-03-2018 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 PIRSF PIRSF003101 2 420 1.7E-152 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 SUPERFAMILY SSF53067 8 221 6.15E-61 T 28-03-2018 WM46_RS14360 e64b4c537ba827d8bf6fde7da46e6287 420 SUPERFAMILY SSF53067 198 384 1.91E-47 T 28-03-2018 WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 SUPERFAMILY SSF55315 2 76 2.47E-20 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 SMART SM00967 4 80 8.8E-21 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 2 243 44.103 T 28-03-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 Pfam PF00588 SpoU rRNA Methylase family 96 236 1.8E-40 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 Gene3D G3DSA:3.30.1330.30 1 76 1.2E-17 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 1 242 1.1E-93 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 Gene3D G3DSA:3.40.1280.10 77 243 3.7E-49 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 SUPERFAMILY SSF75217 68 242 3.86E-49 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS22950 6fb7f69804e385c70aa8877f935bb1e9 243 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 77 3.6E-18 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 WM46_RS14215 2bd7eef50579c104845e852f20b33f7c 423 Pfam PF07005 Putative sugar-binding N-terminal domain 3 225 1.8E-60 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain WM46_RS14215 2bd7eef50579c104845e852f20b33f7c 423 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 240 409 9.1E-39 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain WM46_RS14215 2bd7eef50579c104845e852f20b33f7c 423 Gene3D G3DSA:3.40.50.10840 3 233 3.2E-65 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain WM46_RS14215 2bd7eef50579c104845e852f20b33f7c 423 SUPERFAMILY SSF142764 4 416 6.02E-99 T 28-03-2018 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 SUPERFAMILY SSF48239 1178 1434 3.73E-43 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:2.60.40.10 384 481 3.3E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:2.60.40.10 863 1019 0.082 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 290 383 2.8E-23 T 28-03-2018 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 PIRSF PIRSF038980 1 1653 0.0 T 28-03-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:2.60.40.10 1020 1123 2.5E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1184 1202 8.9E-5 T 28-03-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:2.60.40.10 758 797 0.52 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 SMART SM01359 759 907 3.2E-35 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Pfam PF01835 MG2 domain 389 480 5.0E-20 T 28-03-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:2.60.40.10 295 371 0.047 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 SMART SM01360 969 1058 1.4E-19 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:1.50.10.20 1167 1475 3.7E-27 T 28-03-2018 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Pfam PF00207 Alpha-2-macroglobulin family 976 1058 4.2E-6 T 28-03-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Gene3D G3DSA:2.60.40.10 643 750 0.0055 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00675 5322d99e2cf53501670d9cdf3b536ab4 1653 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 760 907 1.7E-14 T 28-03-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 WM46_RS07850 31fd1249b89574543bdb8ea8b07924b9 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 18 121 7.4E-33 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 WM46_RS07850 31fd1249b89574543bdb8ea8b07924b9 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 103 120 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 WM46_RS07850 31fd1249b89574543bdb8ea8b07924b9 122 SUPERFAMILY SSF89360 18 111 2.94E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS07850 31fd1249b89574543bdb8ea8b07924b9 122 TIGRFAM TIGR01997 sufA_proteo: FeS assembly scaffold SufA 17 122 8.9E-49 T 28-03-2018 IPR011298 FeS assembly scaffold SufA GO:0097428 WM46_RS07850 31fd1249b89574543bdb8ea8b07924b9 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 118 1.9E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS07850 31fd1249b89574543bdb8ea8b07924b9 122 Gene3D G3DSA:2.60.300.12 18 122 9.8E-32 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS17950 60f6ac738fa089f0be9e0df724785a45 218 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 7 213 1.0E-55 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 WM46_RS17950 60f6ac738fa089f0be9e0df724785a45 218 Gene3D G3DSA:3.40.1080.10 1 218 3.9E-68 T 28-03-2018 WM46_RS17950 60f6ac738fa089f0be9e0df724785a45 218 SUPERFAMILY SSF100950 2 215 1.26E-71 T 28-03-2018 WM46_RS17950 60f6ac738fa089f0be9e0df724785a45 218 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS17950 60f6ac738fa089f0be9e0df724785a45 218 SMART SM00882 5 216 1.1E-60 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS17950 60f6ac738fa089f0be9e0df724785a45 218 Pfam PF01144 Coenzyme A transferase 10 214 2.1E-65 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 299 4.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 Gene3D G3DSA:3.30.565.10 303 457 2.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 454 5.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 SUPERFAMILY SSF47384 224 299 3.73E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 SMART SM00388 238 300 2.8E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 Pfam PF16527 Two-component sensor protein CpxA, periplasmic domain 82 146 1.2E-10 T 28-03-2018 IPR032404 Two-component sensor protein CpxA, periplasmic domain WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 SUPERFAMILY SSF55874 289 453 1.81E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 Gene3D G3DSA:1.10.287.130 228 296 8.1E-16 T 28-03-2018 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 Pfam PF00672 HAMP domain 184 234 5.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 SMART SM00304 184 237 1.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 SMART SM00387 345 455 3.9E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 2.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 2.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 2.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS18525 1fa57014448fb61deba9f935ee569b00 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 2.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS06055 51bf2509606c7ec4beed5ccbc2b2c443 296 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 66 2.6E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM46_RS06055 51bf2509606c7ec4beed5ccbc2b2c443 296 SUPERFAMILY SSF161098 90 277 3.4E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06055 51bf2509606c7ec4beed5ccbc2b2c443 296 Gene3D G3DSA:1.10.3720.10 14 285 9.3E-29 T 28-03-2018 WM46_RS06055 51bf2509606c7ec4beed5ccbc2b2c443 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 7.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS16920 881e22ac3ae71ff07f886841b2f907fa 191 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 6 182 5.3E-53 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 WM46_RS16920 881e22ac3ae71ff07f886841b2f907fa 191 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 10 183 4.6E-54 T 28-03-2018 IPR010664 Lipopolysaccharide assembly, LptC-related WM46_RS16920 881e22ac3ae71ff07f886841b2f907fa 191 Gene3D G3DSA:2.60.450.10 25 151 6.3E-6 T 28-03-2018 WM46_RS16920 881e22ac3ae71ff07f886841b2f907fa 191 PIRSF PIRSF028513 1 186 8.7E-41 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 WM46_RS16920 881e22ac3ae71ff07f886841b2f907fa 191 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 4 185 27.638 T 28-03-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 WM46_RS04815 be7a26f7c0c6b7be495bb495f4e34938 79 Pfam PF06183 DinI-like family 17 76 6.9E-21 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS04815 be7a26f7c0c6b7be495bb495f4e34938 79 SUPERFAMILY SSF54857 1 78 2.75E-23 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS04815 be7a26f7c0c6b7be495bb495f4e34938 79 Gene3D G3DSA:3.30.910.10 1 76 9.5E-28 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS04265 0a8adaf56b49a62d81907c2a991289a8 131 Gene3D G3DSA:1.20.120.550 1 127 2.7E-24 T 28-03-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain WM46_RS04265 0a8adaf56b49a62d81907c2a991289a8 131 SUPERFAMILY SSF161084 4 127 9.42E-31 T 28-03-2018 WM46_RS04265 0a8adaf56b49a62d81907c2a991289a8 131 Pfam PF01124 MAPEG family 3 120 6.8E-26 T 28-03-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein WM46_RS03410 80db73b40c6fb21fecf48a433e8ea510 157 Gene3D G3DSA:3.20.80.10 1 157 4.3E-24 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain WM46_RS03410 80db73b40c6fb21fecf48a433e8ea510 157 SMART SM00871 1 153 2.2E-25 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding WM46_RS03410 80db73b40c6fb21fecf48a433e8ea510 157 SUPERFAMILY SSF55136 1 154 1.33E-38 T 28-03-2018 WM46_RS03410 80db73b40c6fb21fecf48a433e8ea510 157 Pfam PF06445 GyrI-like small molecule binding domain 1 152 1.8E-23 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain WM46_RS03410 80db73b40c6fb21fecf48a433e8ea510 157 Hamap MF_01896 DNA gyrase inhibitor [sbmC]. 1 155 39.548 T 28-03-2018 IPR024911 DNA gyrase inhibitor GyrI GO:0008657 WM46_RS19335 6a7c16e9f635555cdae49a170080e25e 309 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 10 307 2.0E-147 T 28-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 WM46_RS19335 6a7c16e9f635555cdae49a170080e25e 309 Pfam PF01063 Amino-transferase class IV 36 268 1.2E-50 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 WM46_RS19335 6a7c16e9f635555cdae49a170080e25e 309 Gene3D G3DSA:3.20.10.10 143 303 3.0E-51 T 28-03-2018 WM46_RS19335 6a7c16e9f635555cdae49a170080e25e 309 SUPERFAMILY SSF56752 7 307 2.49E-106 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 WM46_RS19335 6a7c16e9f635555cdae49a170080e25e 309 Gene3D G3DSA:3.30.470.10 1 142 1.3E-43 T 28-03-2018 WM46_RS19335 6a7c16e9f635555cdae49a170080e25e 309 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 223 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 47 1.8E-15 T 28-03-2018 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 SUPERFAMILY SSF54909 62 151 4.29E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 Pfam PF01037 Lrp/AsnC ligand binding domain 68 142 5.9E-22 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 SUPERFAMILY SSF46785 1 61 3.87E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 SMART SM00344 2 111 4.7E-36 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 Gene3D G3DSA:1.10.10.10 1 50 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 7.8E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 7.8E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 7.8E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 Gene3D G3DSA:3.30.70.920 54 148 2.5E-27 T 28-03-2018 WM46_RS12575 a8d157e5f6283e4839ffef2ce4cc9192 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site WM46_RS14140 dc3420660ccd69186ec8b0373b267503 308 Gene3D G3DSA:3.40.50.300 1 257 2.7E-64 T 28-03-2018 WM46_RS14140 dc3420660ccd69186ec8b0373b267503 308 SUPERFAMILY SSF52540 3 233 2.13E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14140 dc3420660ccd69186ec8b0373b267503 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS14140 dc3420660ccd69186ec8b0373b267503 308 Pfam PF00005 ABC transporter 21 165 2.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS14140 dc3420660ccd69186ec8b0373b267503 308 SMART SM00382 30 213 2.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19580 6f80ba73ae57c9d9f431a6f6474cb7b8 445 PIRSF PIRSF005353 5 444 6.3E-177 T 28-03-2018 IPR026033 Purine permease PbuG-like WM46_RS19580 6f80ba73ae57c9d9f431a6f6474cb7b8 445 Pfam PF00860 Permease family 31 404 4.7E-43 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS25745 27cb749b07ddb83a45137f6737253c8d 499 SUPERFAMILY SSF53474 126 353 9.84E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS25745 27cb749b07ddb83a45137f6737253c8d 499 Pfam PF12146 Serine aminopeptidase, S33 129 253 3.0E-10 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 WM46_RS25745 27cb749b07ddb83a45137f6737253c8d 499 Gene3D G3DSA:3.40.50.1820 82 358 1.2E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82693 565 660 3.82E-17 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82866 299 498 1.7E-44 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Gene3D G3DSA:3.30.70.1430 567 666 4.0E-16 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82714 192 275 5.23E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 47 65 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 PRINTS PR00702 Acriflavin resistance protein family signature 19 43 5.1E-80 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Pfam PF00873 AcrB/AcrD/AcrF family 13 1022 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82866 800 1024 7.06E-44 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82693 49 138 8.89E-23 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Gene3D G3DSA:3.30.2090.10 717 804 3.9E-19 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Gene3D G3DSA:3.30.2090.10 190 275 1.7E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Gene3D G3DSA:3.30.70.1430 49 151 1.1E-23 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Hamap MF_01423 Multidrug resistance protein MdtB [mdtB]. 1 1037 33.673 T 28-03-2018 IPR022831 Multidrug resistance protein MdtB WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82714 719 800 5.62E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82693 146 191 1.31E-21 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 SUPERFAMILY SSF82693 277 333 1.31E-21 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Gene3D G3DSA:1.20.1640.10 276 501 1.8E-43 T 28-03-2018 WM46_RS02740 8fbdb2d93dc1cdeca30eeb31726e92a8 1040 Gene3D G3DSA:1.20.1640.10 815 1036 5.4E-34 T 28-03-2018 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 Gene3D G3DSA:3.90.180.10 1 152 2.2E-46 T 28-03-2018 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 Pfam PF00107 Zinc-binding dehydrogenase 174 301 2.6E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 60.999 T 28-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 Gene3D G3DSA:3.40.50.10730 153 303 9.2E-27 T 28-03-2018 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 3 340 9.2E-189 T 28-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 SUPERFAMILY SSF50129 1 173 7.91E-54 T 28-03-2018 IPR011032 GroES-like WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 3.7E-32 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 SMART SM00829 12 338 8.9E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS20245 3696f14519d7a31b521be77895fcd96e 341 SUPERFAMILY SSF51735 141 305 5.65E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS21975 6e07b94db8c0629129eb69cb1079f653 476 Gene3D G3DSA:1.20.1250.20 7 214 1.2E-12 T 28-03-2018 WM46_RS21975 6e07b94db8c0629129eb69cb1079f653 476 Gene3D G3DSA:1.20.1250.20 220 448 1.0E-11 T 28-03-2018 WM46_RS21975 6e07b94db8c0629129eb69cb1079f653 476 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 59 84 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 WM46_RS21975 6e07b94db8c0629129eb69cb1079f653 476 SUPERFAMILY SSF103473 10 443 4.71E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS21975 6e07b94db8c0629129eb69cb1079f653 476 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 8 450 1.6E-171 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS21975 6e07b94db8c0629129eb69cb1079f653 476 Pfam PF13347 MFS/sugar transport protein 10 436 1.1E-86 T 28-03-2018 WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 Pfam PF07729 FCD domain 100 222 2.5E-23 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 SUPERFAMILY SSF48008 98 230 9.68E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 SUPERFAMILY SSF46785 6 75 4.19E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 Gene3D G3DSA:1.10.10.10 3 73 4.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.5E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 Gene3D G3DSA:1.20.120.530 82 244 8.6E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 SMART SM00345 12 71 1.1E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 3.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS20305 ba47ad4123b4275129741e4b1ea59169 258 SMART SM00895 100 224 2.8E-21 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS07550 555582f2eb9d12a3a33c71d6649cdb0d 365 SUPERFAMILY SSF51395 4 364 3.36E-124 T 28-03-2018 WM46_RS07550 555582f2eb9d12a3a33c71d6649cdb0d 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 344 3.1E-92 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 WM46_RS07550 555582f2eb9d12a3a33c71d6649cdb0d 365 Gene3D G3DSA:3.20.20.70 5 365 1.1E-128 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS15140 0d00ad4913506c2e51edae4c81cdce12 91 SUPERFAMILY SSF111148 1 90 2.22E-40 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM46_RS15140 0d00ad4913506c2e51edae4c81cdce12 91 Gene3D G3DSA:1.10.3880.10 2 89 1.7E-40 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM46_RS15140 0d00ad4913506c2e51edae4c81cdce12 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 27.798 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM46_RS15140 0d00ad4913506c2e51edae4c81cdce12 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 87 4.2E-40 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM46_RS15140 0d00ad4913506c2e51edae4c81cdce12 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 1.0E-38 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM46_RS15140 0d00ad4913506c2e51edae4c81cdce12 91 PIRSF PIRSF029827 1 90 1.6E-44 T 28-03-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 WM46_RS07930 d652a07b031e4c7802aedefb1969c5d1 255 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 156 176 - T 28-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 WM46_RS07930 d652a07b031e4c7802aedefb1969c5d1 255 SUPERFAMILY SSF52402 1 251 8.37E-53 T 28-03-2018 WM46_RS07930 d652a07b031e4c7802aedefb1969c5d1 255 Gene3D G3DSA:3.40.50.620 1 254 9.1E-49 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS07930 d652a07b031e4c7802aedefb1969c5d1 255 Pfam PF01012 Electron transfer flavoprotein domain 29 207 1.7E-34 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS07930 d652a07b031e4c7802aedefb1969c5d1 255 SMART SM00893 23 212 1.1E-31 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS07930 d652a07b031e4c7802aedefb1969c5d1 255 PIRSF PIRSF000090 1 255 4.1E-59 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 6 202 1.1E-70 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 4.3E-103 T 28-03-2018 IPR010016 KipI family WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 SUPERFAMILY SSF160467 5 92 5.36E-10 T 28-03-2018 WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 SMART SM00796 4 202 5.2E-94 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 Gene3D G3DSA:3.30.1360.40 1 82 8.7E-10 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 Gene3D G3DSA:2.40.100.10 86 217 7.9E-51 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS11060 80ab16410e98fafd60ab0f5b091c6c84 218 SUPERFAMILY SSF50891 88 214 3.45E-46 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS23895 3da670128e6740da8d77988717acb82b 319 SUPERFAMILY SSF90002 224 315 3.92E-25 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal WM46_RS23895 3da670128e6740da8d77988717acb82b 319 SUPERFAMILY SSF52540 3 202 7.78E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23895 3da670128e6740da8d77988717acb82b 319 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 182 5.7E-51 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain WM46_RS23895 3da670128e6740da8d77988717acb82b 319 SMART SM00833 224 317 3.1E-11 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal WM46_RS23895 3da670128e6740da8d77988717acb82b 319 Gene3D G3DSA:3.40.50.300 1 202 1.8E-45 T 28-03-2018 WM46_RS23895 3da670128e6740da8d77988717acb82b 319 Gene3D G3DSA:3.30.1220.10 209 318 1.9E-21 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal WM46_RS23895 3da670128e6740da8d77988717acb82b 319 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 224 315 7.6E-19 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal WM46_RS07475 9ed200bafb6ea618103edc56299845c5 201 Gene3D G3DSA:3.40.30.10 1 99 4.0E-18 T 28-03-2018 WM46_RS07475 9ed200bafb6ea618103edc56299845c5 201 Gene3D G3DSA:1.20.1050.10 100 201 2.5E-24 T 28-03-2018 WM46_RS07475 9ed200bafb6ea618103edc56299845c5 201 SUPERFAMILY SSF52833 1 79 2.01E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS07475 9ed200bafb6ea618103edc56299845c5 201 SUPERFAMILY SSF47616 83 199 7.1E-30 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS07475 9ed200bafb6ea618103edc56299845c5 201 Pfam PF13409 Glutathione S-transferase, N-terminal domain 14 75 6.0E-9 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS07475 9ed200bafb6ea618103edc56299845c5 201 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 189 5.6E-14 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS09375 35a9e71848ae965a0b273cf46064853b 166 Gene3D G3DSA:3.40.1650.10 3 132 7.1E-25 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS09375 35a9e71848ae965a0b273cf46064853b 166 Pfam PF05025 RbsD / FucU transport protein family 1 130 4.8E-29 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS09375 35a9e71848ae965a0b273cf46064853b 166 SUPERFAMILY SSF102546 1 129 2.75E-29 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS22945 1bc542bf111b14322690d2c0e0a7f604 258 Gene3D G3DSA:3.40.50.300 1 251 1.3E-61 T 28-03-2018 WM46_RS22945 1bc542bf111b14322690d2c0e0a7f604 258 SUPERFAMILY SSF52540 4 231 1.57E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22945 1bc542bf111b14322690d2c0e0a7f604 258 Pfam PF00005 ABC transporter 23 162 3.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS22945 1bc542bf111b14322690d2c0e0a7f604 258 SMART SM00382 32 212 3.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS22945 1bc542bf111b14322690d2c0e0a7f604 258 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS05600 a420b6dcad23e8d34ffc42c2af7934de 117 Pfam PF02635 DsrE/DsrF-like family 2 117 1.7E-22 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein WM46_RS05600 a420b6dcad23e8d34ffc42c2af7934de 117 SUPERFAMILY SSF75169 1 117 1.03E-34 T 28-03-2018 IPR027396 DsrEFH-like WM46_RS05600 a420b6dcad23e8d34ffc42c2af7934de 117 Gene3D G3DSA:3.40.1260.10 1 117 6.9E-29 T 28-03-2018 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 8.6E-26 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 131 8.7E-32 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 4.8E-32 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 4.8E-32 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 4.8E-32 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 222 4.8E-32 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Gene3D G3DSA:3.40.120.10 1 160 1.2E-39 T 28-03-2018 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 153 258 6.9E-22 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 SUPERFAMILY SSF55957 373 456 6.8E-17 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Gene3D G3DSA:3.40.120.10 268 369 4.6E-28 T 28-03-2018 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 444 3.6E-9 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Gene3D G3DSA:3.30.310.50 370 456 3.5E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 Gene3D G3DSA:3.40.120.10 161 267 5.6E-31 T 28-03-2018 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 SUPERFAMILY SSF53738 3 176 1.33E-38 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 SUPERFAMILY SSF53738 153 261 5.49E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS02865 9e7768deb3c22791b1a18c10b5fa76a5 456 SUPERFAMILY SSF53738 263 368 1.06E-32 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 WM46_RS22450 c690601c00aaee77cf59c549437837e1 249 Gene3D G3DSA:2.60.40.1090 74 249 2.5E-4 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS15150 3816abbf46c877e21de590316d74419e 418 Hamap MF_02049 Nucleoside permease NupG [nupG]. 1 417 48.716 T 28-03-2018 IPR033667 Nucleoside permease NupG GO:0005887|GO:1901642 WM46_RS15150 3816abbf46c877e21de590316d74419e 418 TIGRFAM TIGR00889 2A0110: nucleoside transporter 1 418 6.7E-217 T 28-03-2018 IPR004740 Nucleoside:H+ symporter GO:0005337|GO:0015858|GO:0016021 WM46_RS15150 3816abbf46c877e21de590316d74419e 418 Gene3D G3DSA:1.20.1250.20 5 194 4.4E-8 T 28-03-2018 WM46_RS15150 3816abbf46c877e21de590316d74419e 418 Pfam PF03825 Nucleoside H+ symporter 1 406 3.4E-182 T 28-03-2018 WM46_RS15150 3816abbf46c877e21de590316d74419e 418 Gene3D G3DSA:1.20.1250.20 195 409 3.4E-20 T 28-03-2018 WM46_RS15150 3816abbf46c877e21de590316d74419e 418 SUPERFAMILY SSF103473 9 406 1.07E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 SUPERFAMILY SSF52540 3 248 4.13E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 PIRSF PIRSF037116 1 252 8.7E-140 T 28-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 Gene3D G3DSA:3.40.50.300 2 252 7.3E-63 T 28-03-2018 WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 SMART SM00382 30 223 4.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 3 250 3.9E-123 T 28-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 Pfam PF00005 ABC transporter 22 173 3.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21855 6a77cbc523317e7243e3aa38d3240291 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 SUPERFAMILY SSF52467 189 362 5.73E-63 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 569 7.7E-281 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 Gene3D G3DSA:3.40.50.970 356 558 1.0E-52 T 28-03-2018 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 SUPERFAMILY SSF52518 371 567 2.5E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 331 1.9E-46 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 166 2.2E-57 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 431 450 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 Gene3D G3DSA:3.40.50.1220 196 355 1.9E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 Gene3D G3DSA:3.40.50.970 1 195 2.0E-65 T 28-03-2018 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 545 1.8E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS14440 ba6352dfe6d5f3d63df88f0cd46b663d 574 SUPERFAMILY SSF52518 2 174 2.17E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS21575 a6e448034fe21f4461e579d39b2ed230 165 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 12 165 25.152 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 WM46_RS21575 a6e448034fe21f4461e579d39b2ed230 165 Pfam PF04345 Chorismate lyase 18 165 9.6E-32 T 28-03-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745 WM46_RS21575 a6e448034fe21f4461e579d39b2ed230 165 SUPERFAMILY SSF64288 6 165 3.71E-46 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS21575 a6e448034fe21f4461e579d39b2ed230 165 Gene3D G3DSA:3.40.1410.10 2 165 2.9E-46 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS12195 08b8ccb5b03597ff59665ba82c8da97a 499 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 399 483 4.0E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS12195 08b8ccb5b03597ff59665ba82c8da97a 499 Pfam PF02378 Phosphotransferase system, EIIC 19 336 8.9E-78 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS12195 08b8ccb5b03597ff59665ba82c8da97a 499 Pfam PF00367 phosphotransferase system, EIIB 426 458 7.3E-10 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS12195 08b8ccb5b03597ff59665ba82c8da97a 499 Gene3D G3DSA:3.30.1360.60 421 497 1.6E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS12195 08b8ccb5b03597ff59665ba82c8da97a 499 SUPERFAMILY SSF55604 423 497 2.09E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS16480 5e559bf817d467a52457add0d55a2358 454 Pfam PF03313 Serine dehydratase alpha chain 184 448 9.1E-96 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit WM46_RS16480 5e559bf817d467a52457add0d55a2358 454 Gene3D G3DSA:1.10.4100.10 265 442 2.4E-33 T 28-03-2018 WM46_RS16480 5e559bf817d467a52457add0d55a2358 454 Pfam PF03315 Serine dehydratase beta chain 3 155 2.3E-54 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM46_RS16480 5e559bf817d467a52457add0d55a2358 454 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 2 451 2.2E-216 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 WM46_RS16480 5e559bf817d467a52457add0d55a2358 454 Gene3D G3DSA:3.30.1330.90 11 158 1.9E-51 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 WM46_RS16480 5e559bf817d467a52457add0d55a2358 454 SUPERFAMILY SSF143548 16 158 3.4E-44 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 187 1.6E-4 T 28-03-2018 WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 249 9.8E-54 T 28-03-2018 WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.0E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.0E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.0E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.0E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.0E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 5.0E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 Gene3D G3DSA:3.40.50.720 2 38 2.8E-6 T 28-03-2018 WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 Gene3D G3DSA:3.40.50.720 39 251 1.4E-57 T 28-03-2018 WM46_RS15210 a02195842129c5862ad2d551d7b5d93e 251 SUPERFAMILY SSF51735 6 251 1.34E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 2.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 2.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 2.2E-22 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 PIRSF PIRSF000349 1 193 1.6E-87 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 Gene3D G3DSA:1.10.287.990 20 82 2.4E-28 T 28-03-2018 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 1.8E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 1.1E-39 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 SUPERFAMILY SSF46609 1 84 1.7E-36 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS07605 9805b2c180fbfcc2ed16e5398b527839 193 SUPERFAMILY SSF54719 84 192 2.23E-45 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS02430 48dfe17bfbd6eaa6af75eeeac66133c7 278 SUPERFAMILY SSF53474 1 276 3.51E-89 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS02430 48dfe17bfbd6eaa6af75eeeac66133c7 278 Gene3D G3DSA:3.40.50.1820 1 277 2.3E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS02430 48dfe17bfbd6eaa6af75eeeac66133c7 278 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 276 2.2E-118 T 28-03-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 WM46_RS02430 48dfe17bfbd6eaa6af75eeeac66133c7 278 Pfam PF00756 Putative esterase 21 271 3.0E-72 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 Pfam PF10114 Sensory domain found in PocR 12 162 1.6E-33 T 28-03-2018 IPR018771 PocR domain WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 Pfam PF12833 Helix-turn-helix domain 214 292 3.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 SUPERFAMILY SSF46689 192 241 7.37E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 SMART SM00342 208 291 5.0E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 Gene3D G3DSA:1.10.10.60 246 295 8.6E-10 T 28-03-2018 WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 SUPERFAMILY SSF46689 245 293 2.64E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 Gene3D G3DSA:2.60.120.10 8 245 1.5E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS10925 991a0bfc40019b514c75fa1bb59e56b0 297 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 245 287 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 3 181 3.9E-59 T 28-03-2018 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 SMART SM00855 2 156 3.1E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 Gene3D G3DSA:3.40.50.1240 1 201 2.9E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 SUPERFAMILY SSF53254 1 197 9.93E-55 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 194 1.3E-54 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS11375 c4cc91afa05f49127b7dee700d8b1742 203 PIRSF PIRSF000709 1 181 1.5E-14 T 28-03-2018 WM46_RS25785 609b85e62332c21894974221ef6b4225 854 SUPERFAMILY SSF51126 103 510 1.51E-25 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS25785 609b85e62332c21894974221ef6b4225 854 Gene3D G3DSA:2.160.20.20 18 515 2.7E-40 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS25785 609b85e62332c21894974221ef6b4225 854 SMART SM00869 574 843 3.5E-42 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS25785 609b85e62332c21894974221ef6b4225 854 Pfam PF03797 Autotransporter beta-domain 577 832 5.1E-46 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS25785 609b85e62332c21894974221ef6b4225 854 Gene3D G3DSA:2.40.128.130 531 854 6.4E-52 T 28-03-2018 WM46_RS25785 609b85e62332c21894974221ef6b4225 854 SUPERFAMILY SSF103515 537 854 4.45E-52 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS25785 609b85e62332c21894974221ef6b4225 854 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 413 854 3.6E-112 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS03420 c6c5d0bbdcf5c0b15a9cbb6f2d39f59c 111 PIRSF PIRSF028773 1 111 5.7E-54 T 28-03-2018 IPR007458 Protein of unknown function DUF496 WM46_RS03420 c6c5d0bbdcf5c0b15a9cbb6f2d39f59c 111 Pfam PF04363 Protein of unknown function (DUF496) 8 99 6.1E-46 T 28-03-2018 IPR007458 Protein of unknown function DUF496 WM46_RS03420 c6c5d0bbdcf5c0b15a9cbb6f2d39f59c 111 Hamap MF_00683 UPF0265 protein YeeX [yeeX]. 8 102 25.672 T 28-03-2018 IPR007458 Protein of unknown function DUF496 WM46_RS03420 c6c5d0bbdcf5c0b15a9cbb6f2d39f59c 111 ProDom PD030876 UPF0265 YEEX HELIX ALPHA BFL460 UNCHARACTERIZED FN0411 HI1168 VPA1226 BCR 11 98 5.0E-43 T 28-03-2018 IPR007458 Protein of unknown function DUF496 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 Gene3D G3DSA:3.40.50.10380 5 160 3.3E-36 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 SUPERFAMILY SSF53223 10 161 4.75E-54 T 28-03-2018 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 SMART SM00919 163 401 1.4E-143 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 SUPERFAMILY SSF51735 163 453 8.22E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS00945 c80777c87b4685b10b684cf561205989 759 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 SUPERFAMILY SSF53659 430 754 9.05E-93 T 28-03-2018 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 PIRSF PIRSF036684 1 758 0.0 T 28-03-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 751 2.4E-101 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 Gene3D G3DSA:3.40.50.720 161 448 1.3E-84 T 28-03-2018 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 Gene3D G3DSA:3.40.50.10750 573 727 6.1E-51 T 28-03-2018 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 SMART SM01274 18 151 2.3E-82 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 9.4E-29 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 WM46_RS00945 c80777c87b4685b10b684cf561205989 759 Pfam PF03949 Malic enzyme, NAD binding domain 165 360 2.9E-20 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 WM46_RS01110 10700c7aa8537c9d76ed0ddf8bd20a52 288 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 21 284 2.3E-52 T 28-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 WM46_RS01110 10700c7aa8537c9d76ed0ddf8bd20a52 288 Gene3D G3DSA:3.40.1190.20 18 278 3.1E-48 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS01110 10700c7aa8537c9d76ed0ddf8bd20a52 288 Pfam PF08543 Phosphomethylpyrimidine kinase 93 269 5.5E-25 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 WM46_RS01110 10700c7aa8537c9d76ed0ddf8bd20a52 288 SUPERFAMILY SSF53613 22 279 2.03E-60 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS07295 81557eb2bdf9f07c3de9e8211c37df65 117 Hamap MF_00546 Acid shock protein [asr]. 10 117 16.882 T 28-03-2018 IPR023497 Acid shock protein WM46_RS13865 0690e82f29f84847300035222bd0d833 181 SMART SM01322 1 176 9.5E-108 T 28-03-2018 IPR009822 YaeQ WM46_RS13865 0690e82f29f84847300035222bd0d833 181 PIRSF PIRSF011484 1 179 1.2E-64 T 28-03-2018 IPR009822 YaeQ WM46_RS13865 0690e82f29f84847300035222bd0d833 181 Gene3D G3DSA:3.10.640.10 2 177 1.2E-73 T 28-03-2018 WM46_RS13865 0690e82f29f84847300035222bd0d833 181 Pfam PF07152 YaeQ protein 1 173 7.7E-71 T 28-03-2018 IPR009822 YaeQ WM46_RS13865 0690e82f29f84847300035222bd0d833 181 SUPERFAMILY SSF52980 4 178 3.49E-68 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 Gene3D G3DSA:3.40.50.1000 1 32 0.1 T 28-03-2018 IPR023214 HAD-like domain WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 Gene3D G3DSA:3.30.1240.10 82 174 1.5E-18 T 28-03-2018 WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 ProSitePatterns PS01229 Hypothetical cof family signature 2. 212 234 - T 28-03-2018 WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 Gene3D G3DSA:3.40.50.1000 175 266 4.5E-19 T 28-03-2018 IPR023214 HAD-like domain WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 258 1.2E-43 T 28-03-2018 IPR023214 HAD-like domain WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 258 1.6E-43 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 5.7E-18 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS22550 81640ee23d6b943f2990b2dc97511248 266 SUPERFAMILY SSF56784 1 262 2.1E-58 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 607 30.154 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 386 542 1.5E-45 T 28-03-2018 IPR001162 UvrC family homology region WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Pfam PF01541 GIY-YIG catalytic domain 18 93 1.5E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 SUPERFAMILY SSF46600 190 243 7.59E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Gene3D G3DSA:1.10.150.20 526 567 0.32 T 28-03-2018 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 9 589 2.7E-237 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 SMART SM00278 588 607 2.9 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 SMART SM00278 556 575 1.1 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Pfam PF14520 Helix-hairpin-helix domain 558 609 5.4E-8 T 28-03-2018 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 SUPERFAMILY SSF47781 521 606 5.4E-17 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 SMART SM00465 17 98 9.7E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Gene3D G3DSA:3.40.1440.10 4 101 4.6E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Gene3D G3DSA:4.10.860.10 182 242 8.7E-16 T 28-03-2018 IPR001943 UVR domain GO:0005515 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Pfam PF02151 UvrB/uvrC motif 205 237 2.2E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 Gene3D G3DSA:1.10.150.20 568 609 6.1E-11 T 28-03-2018 WM46_RS03935 d1b0a18995059691965cbe12d45b5353 610 SUPERFAMILY SSF82771 17 100 7.59E-24 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS14605 fb8144b3a39a80e2586f9999a63f421b 443 Gene3D G3DSA:1.20.1250.20 12 210 1.7E-32 T 28-03-2018 WM46_RS14605 fb8144b3a39a80e2586f9999a63f421b 443 Pfam PF00083 Sugar (and other) transporter 32 434 6.0E-50 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS14605 fb8144b3a39a80e2586f9999a63f421b 443 Gene3D G3DSA:1.20.1250.20 222 441 4.8E-31 T 28-03-2018 WM46_RS14605 fb8144b3a39a80e2586f9999a63f421b 443 SUPERFAMILY SSF103473 8 429 1.96E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 PIRSF PIRSF036979 21 312 2.8E-25 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 Gene3D G3DSA:3.40.800.10 2 313 1.6E-74 T 28-03-2018 WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 SUPERFAMILY SSF52768 11 312 4.86E-74 T 28-03-2018 WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 TIGRFAM TIGR01227 hutG: formimidoylglutamase 12 308 1.9E-83 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 Pfam PF00491 Arginase family 45 308 2.1E-52 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 WM46_RS10620 0a4a876425bab6e12f577e3d9495d723 313 Hamap MF_00737 Formimidoylglutamase [hutG]. 7 310 41.81 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 WM46_RS06060 8d72b9cb46a25d3d5348fe902113efec 321 Gene3D G3DSA:1.10.3720.10 4 303 3.5E-42 T 28-03-2018 WM46_RS06060 8d72b9cb46a25d3d5348fe902113efec 321 SUPERFAMILY SSF161098 70 138 7.19E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06060 8d72b9cb46a25d3d5348fe902113efec 321 SUPERFAMILY SSF161098 178 300 7.19E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06060 8d72b9cb46a25d3d5348fe902113efec 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 311 2.8E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS23140 912620f5b1918b2c3df8b38d560d7160 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.875 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS23140 912620f5b1918b2c3df8b38d560d7160 176 SUPERFAMILY SSF50324 4 173 3.53E-67 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS23140 912620f5b1918b2c3df8b38d560d7160 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS23140 912620f5b1918b2c3df8b38d560d7160 176 Gene3D G3DSA:3.90.80.10 3 176 4.2E-54 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS23140 912620f5b1918b2c3df8b38d560d7160 176 Pfam PF00719 Inorganic pyrophosphatase 18 172 2.6E-55 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 Gene3D G3DSA:3.40.50.300 437 621 2.3E-12 T 28-03-2018 WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 Pfam PF13307 Helicase C-terminal domain 459 616 2.3E-34 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 SUPERFAMILY SSF52540 13 232 1.77E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 SUPERFAMILY SSF52540 40 88 6.17E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 SUPERFAMILY SSF52540 573 597 6.17E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 SUPERFAMILY SSF52540 477 542 6.17E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 SMART SM00491 474 603 3.8E-55 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 Gene3D G3DSA:3.40.50.300 17 417 9.9E-32 T 28-03-2018 WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 Pfam PF04851 Type III restriction enzyme, res subunit 18 232 2.7E-6 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 WM46_RS05005 b574bc8b1296498f15bb8609bfc6efc8 636 SMART SM00487 16 286 0.0016 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS15005 67e10b93c79378d670bd6de0ccb7545f 252 Gene3D G3DSA:3.30.2010.10 60 147 1.0E-18 T 28-03-2018 WM46_RS15005 67e10b93c79378d670bd6de0ccb7545f 252 Pfam PF01435 Peptidase family M48 71 245 5.2E-26 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 Pfam PF05239 PRC-barrel domain 104 177 1.6E-9 T 28-03-2018 IPR027275 PRC-barrel domain WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 Pfam PF01782 RimM N-terminal domain 16 96 1.9E-26 T 28-03-2018 IPR002676 RimM protein GO:0006364 WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 Gene3D G3DSA:2.40.30.60 12 100 2.9E-27 T 28-03-2018 IPR002676 RimM protein GO:0006364 WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 14 182 3.7E-62 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 SUPERFAMILY SSF50346 106 182 1.47E-19 T 28-03-2018 IPR011033 PRC-barrel-like WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 Gene3D G3DSA:2.30.30.240 102 177 1.2E-22 T 28-03-2018 WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 13 182 24.696 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 WM46_RS00190 199ff117565a2b2f5a027db337ecadab 182 SUPERFAMILY SSF50447 12 100 1.59E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 1 424 51.665 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 PIRSF PIRSF000521 25 422 3.1E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 SUPERFAMILY SSF53383 1 422 9.88E-138 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 Gene3D G3DSA:3.90.1150.10 3 183 2.9E-47 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 242 279 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 Gene3D G3DSA:3.90.1150.10 258 424 8.2E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 Pfam PF00202 Aminotransferase class-III 26 420 3.6E-131 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 Gene3D G3DSA:3.90.1150.10 187 257 0.0092 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS10595 bc06fa798a81de40b917ca3c50639f16 429 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 13 421 1.3E-183 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 Gene3D G3DSA:2.30.40.10 7 81 1.9E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 SUPERFAMILY SSF51338 369 406 1.09E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 SUPERFAMILY SSF51338 8 68 1.09E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 Gene3D G3DSA:3.20.20.140 82 367 4.7E-50 T 28-03-2018 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 SUPERFAMILY SSF51556 68 367 2.27E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 TIGRFAM TIGR01224 hutI: imidazolonepropionase 32 406 1.7E-141 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 Pfam PF01979 Amidohydrolase family 65 385 2.7E-14 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS10625 d5a329fb6ca5d9a1d39d57fe967ae68d 407 Hamap MF_00372 Imidazolonepropionase [hutI]. 8 407 39.644 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.7E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 SUPERFAMILY SSF46785 5 60 1.53E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 SMART SM00420 6 58 1.2E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.0E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.0E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 Gene3D G3DSA:1.10.10.10 1 59 3.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 SUPERFAMILY SSF100950 74 234 1.34E-27 T 28-03-2018 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 Pfam PF00455 DeoR C terminal sensor domain 74 232 2.1E-43 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 Gene3D G3DSA:3.40.50.1360 72 237 1.0E-33 T 28-03-2018 WM46_RS21445 d4903bbe8acc26fd5b69e780434c1bb5 252 SMART SM01134 72 233 1.0E-58 T 28-03-2018 WM46_RS09505 c8cc6f1ff40da55766703791b93b53e3 196 SUPERFAMILY SSF55826 24 178 3.92E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS09505 c8cc6f1ff40da55766703791b93b53e3 196 Pfam PF04073 Aminoacyl-tRNA editing domain 44 170 7.3E-25 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS09505 c8cc6f1ff40da55766703791b93b53e3 196 Gene3D G3DSA:3.90.960.10 20 184 2.1E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Gene3D G3DSA:3.40.640.10 530 774 4.1E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Gene3D G3DSA:3.90.1150.10 343 442 8.1E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 17 950 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Gene3D G3DSA:3.90.1150.10 775 907 1.0E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Gene3D G3DSA:3.40.640.10 96 342 1.6E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Pfam PF02347 Glycine cleavage system P-protein 481 739 3.3E-8 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Pfam PF02347 Glycine cleavage system P-protein 16 440 6.8E-191 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 SUPERFAMILY SSF53383 17 440 4.66E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 SUPERFAMILY SSF53383 929 951 9.46E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 SUPERFAMILY SSF53383 480 889 9.46E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS24210 490b2b9e22a06dcffaaf8a9f94dfc8f3 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 8 956 25.543 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 303 316 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 SUPERFAMILY SSF53613 61 355 4.05E-53 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 Pfam PF00294 pfkB family carbohydrate kinase 58 347 1.5E-60 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 8.2E-11 T 28-03-2018 WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 SUPERFAMILY SSF46785 1 54 7.71E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 Gene3D G3DSA:1.10.10.10 1 52 3.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 93 117 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS02400 7264e1c3b73d5fa536b1b95bb3c1fef3 364 Gene3D G3DSA:3.40.1190.20 53 353 4.2E-48 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 TIGRFAM TIGR02085 meth_trns_rumB: 23S rRNA (uracil-5-)-methyltransferase RumB 2 373 2.8E-214 T 28-03-2018 IPR011825 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC GO:0016070|GO:0016436 WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 Hamap MF_01012 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC [rlmC]. 1 375 79.682 T 28-03-2018 IPR011825 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC GO:0016070|GO:0016436 WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 Pfam PF13847 Methyltransferase domain 236 294 1.4E-7 T 28-03-2018 IPR025714 Methyltransferase domain WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 357 367 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 SUPERFAMILY SSF53335 3 373 3.29E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 307 338 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 Gene3D G3DSA:3.40.50.150 1 373 1.2E-43 T 28-03-2018 WM46_RS10135 fe85fe08919da22b72376cb856f7b2ad 375 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 303 373 2.8E-10 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 WM46_RS12295 975ace8a4e84482587e93f7fd712d9fb 152 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 149 2.3E-24 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain WM46_RS12295 975ace8a4e84482587e93f7fd712d9fb 152 Gene3D G3DSA:2.40.50.140 81 152 1.6E-13 T 28-03-2018 WM46_RS12295 975ace8a4e84482587e93f7fd712d9fb 152 SUPERFAMILY SSF141322 95 150 2.75E-5 T 28-03-2018 WM46_RS20650 eeefc7142e7ab8d6e44d880feee21d5a 62 Pfam PF10945 Cellulose biosynthesis protein BcsR 18 59 4.2E-23 T 28-03-2018 IPR024487 Cellulose biosynthesis protein BcsR WM46_RS20650 eeefc7142e7ab8d6e44d880feee21d5a 62 ProDom PD053230 YHJR ECS4415 STY4179 CYTOPLASMIC 1 60 2.0E-25 T 28-03-2018 IPR024487 Cellulose biosynthesis protein BcsR WM46_RS19030 93ef826d643f0413b8ddec4f4b7718ee 269 Gene3D G3DSA:3.40.50.1820 26 265 9.3E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS19030 93ef826d643f0413b8ddec4f4b7718ee 269 Pfam PF01738 Dienelactone hydrolase family 42 265 7.9E-77 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 WM46_RS19030 93ef826d643f0413b8ddec4f4b7718ee 269 SUPERFAMILY SSF53474 34 264 1.09E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 Gene3D G3DSA:3.30.420.10 151 347 3.0E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 ProSitePatterns PS00116 DNA polymerase family B signature. 543 551 - T 28-03-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 Pfam PF03104 DNA polymerase family B, exonuclease domain 198 296 3.3E-7 T 28-03-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 Pfam PF03104 DNA polymerase family B, exonuclease domain 75 164 3.9E-6 T 28-03-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 Pfam PF00136 DNA polymerase family B 398 736 2.0E-40 T 28-03-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 SMART SM00486 148 555 9.9E-81 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 SUPERFAMILY SSF53098 3 389 2.62E-95 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 415 428 7.0E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 489 501 7.0E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 541 549 7.0E-10 T 28-03-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 Gene3D G3DSA:3.90.1600.10 404 636 4.1E-50 T 28-03-2018 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS14530 3f311016faf99d1ee3ad06df0a052001 783 SUPERFAMILY SSF56672 385 777 2.5E-113 T 28-03-2018 WM46_RS10120 73028c96fe9cac35b00926ad2e25216c 238 Gene3D G3DSA:1.10.3720.10 2 236 3.3E-35 T 28-03-2018 WM46_RS10120 73028c96fe9cac35b00926ad2e25216c 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 230 1.2E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10120 73028c96fe9cac35b00926ad2e25216c 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 6 80 6.3E-12 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS10120 73028c96fe9cac35b00926ad2e25216c 238 SUPERFAMILY SSF161098 8 216 5.1E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08890 383cd7e03b79455dca2177c8d64399bd 306 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 5 306 3.1E-146 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 WM46_RS08890 383cd7e03b79455dca2177c8d64399bd 306 PIRSF PIRSF026649 2 306 1.3E-109 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM46_RS08890 383cd7e03b79455dca2177c8d64399bd 306 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 4 306 51.221 T 28-03-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24 WM46_RS08890 383cd7e03b79455dca2177c8d64399bd 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 297 1.2E-117 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 Gene3D G3DSA:3.30.70.100 985 1079 1.0E-11 T 28-03-2018 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 947 981 - T 28-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 SUPERFAMILY SSF82689 985 1083 5.89E-16 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 Pfam PF00924 Mechanosensitive ion channel 875 1074 1.7E-53 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 Gene3D G3DSA:2.30.30.60 933 982 2.0E-12 T 28-03-2018 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 SUPERFAMILY SSF82861 834 916 2.62E-8 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 Pfam PF12795 Mechanosensitive ion channel porin domain 31 255 4.7E-58 T 28-03-2018 IPR024393 Mechanosensitive ion channel MscS, porin domain WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 SUPERFAMILY SSF50182 918 983 7.52E-17 T 28-03-2018 IPR010920 LSM domain WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 Gene3D G3DSA:1.20.5.110 25 799 1.8E-6 T 28-03-2018 WM46_RS22820 0d7638c9d04c7c07235b341db413e49c 1108 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 478 814 4.7E-114 T 28-03-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 319 1.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 SMART SM00387 363 473 3.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 SUPERFAMILY SSF55874 311 469 4.45E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 SMART SM00304 204 255 9.1E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 SMART SM00388 255 320 1.1E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 SUPERFAMILY SSF47384 241 320 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 Gene3D G3DSA:3.30.450.20 28 177 8.6E-26 T 28-03-2018 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 5.8E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 5.8E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 5.8E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 Pfam PF17203 Single cache domain 3 35 168 1.6E-7 T 28-03-2018 IPR033463 Single cache domain 3 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 Gene3D G3DSA:1.10.287.130 235 314 5.5E-10 T 28-03-2018 WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 SUPERFAMILY SSF103190 57 177 2.24E-13 T 28-03-2018 IPR029151 Periplasmic sensor domain-like WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 470 1.2E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS14840 b5c8ef249248d9fd1aa7cc1594c1028b 474 Gene3D G3DSA:3.30.565.10 315 472 6.1E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11600 59802807e7d084eff2ac0fe69039a0fa 412 Gene3D G3DSA:1.20.1250.20 9 210 1.0E-22 T 28-03-2018 WM46_RS11600 59802807e7d084eff2ac0fe69039a0fa 412 SUPERFAMILY SSF103473 16 404 8.5E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS11600 59802807e7d084eff2ac0fe69039a0fa 412 Pfam PF05977 Transmembrane secretion effector 16 405 1.1E-18 T 28-03-2018 IPR010290 Transmembrane secretion effector WM46_RS11600 59802807e7d084eff2ac0fe69039a0fa 412 Hamap MF_01436 Enterobactin exporter EntS [entS]. 1 412 43.622 T 28-03-2018 IPR023722 Enterobactin exporter, EntS GO:0005886|GO:0042930|GO:0042931 WM46_RS11600 59802807e7d084eff2ac0fe69039a0fa 412 Gene3D G3DSA:1.20.1250.20 211 410 5.0E-14 T 28-03-2018 WM46_RS13745 f9d1837c92b8847b282d24a5601cb37e 155 SUPERFAMILY SSF53098 4 141 1.77E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13745 f9d1837c92b8847b282d24a5601cb37e 155 Pfam PF00075 RNase H 3 141 1.9E-53 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 WM46_RS13745 f9d1837c92b8847b282d24a5601cb37e 155 Gene3D G3DSA:3.30.420.10 1 154 3.4E-53 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13745 f9d1837c92b8847b282d24a5601cb37e 155 Hamap MF_00042 Ribonuclease H [rnhA]. 2 150 39.501 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 WM46_RS07330 3bd5feaabe44375f98f278e3f9540db7 462 PIRSF PIRSF000204 1 462 1.3E-238 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 WM46_RS07330 3bd5feaabe44375f98f278e3f9540db7 462 Gene3D G3DSA:3.40.50.1220 289 462 1.1E-91 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS07330 3bd5feaabe44375f98f278e3f9540db7 462 SUPERFAMILY SSF52467 289 462 9.35E-79 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS07330 3bd5feaabe44375f98f278e3f9540db7 462 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 460 1.1E-202 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 WM46_RS20195 ed9b188f95f7ed5f3463f4b3b4453bd1 337 Pfam PF08437 Glycosyl transferase family 8 C-terminal 278 334 2.7E-18 T 28-03-2018 IPR013645 Glycosyl transferase, family 8, C-terminal GO:0008918|GO:0009103 WM46_RS20195 ed9b188f95f7ed5f3463f4b3b4453bd1 337 Gene3D G3DSA:3.90.550.10 28 319 3.1E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS20195 ed9b188f95f7ed5f3463f4b3b4453bd1 337 Pfam PF01501 Glycosyl transferase family 8 29 275 1.1E-65 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 WM46_RS20195 ed9b188f95f7ed5f3463f4b3b4453bd1 337 SUPERFAMILY SSF53448 29 298 2.31E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS14575 ca85bd275ab7c6f04ac97da4b49b3efa 282 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 278 5.7E-165 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 WM46_RS14575 ca85bd275ab7c6f04ac97da4b49b3efa 282 SUPERFAMILY SSF56300 1 261 5.86E-59 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS14575 ca85bd275ab7c6f04ac97da4b49b3efa 282 Pfam PF00149 Calcineurin-like phosphoesterase 4 140 2.4E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS14575 ca85bd275ab7c6f04ac97da4b49b3efa 282 PIRSF PIRSF000903 1 274 5.6E-124 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 WM46_RS14575 ca85bd275ab7c6f04ac97da4b49b3efa 282 Gene3D G3DSA:3.60.21.10 1 281 9.7E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS14575 ca85bd275ab7c6f04ac97da4b49b3efa 282 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 52.237 T 28-03-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 WM46_RS02285 4a423683aac53383b7b123e4a30ffc0b 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 338 1.2E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS02285 4a423683aac53383b7b123e4a30ffc0b 341 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 9 46 6.3E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM46_RS02285 4a423683aac53383b7b123e4a30ffc0b 341 Gene3D G3DSA:1.10.3720.10 10 328 1.1E-40 T 28-03-2018 WM46_RS02285 4a423683aac53383b7b123e4a30ffc0b 341 SUPERFAMILY SSF161098 135 321 1.28E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07840 cf6117a2ce2fdbf435f7cc5cba97c223 248 Gene3D G3DSA:3.40.50.300 1 248 1.6E-43 T 28-03-2018 WM46_RS07840 cf6117a2ce2fdbf435f7cc5cba97c223 248 SUPERFAMILY SSF52540 2 231 9.83E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07840 cf6117a2ce2fdbf435f7cc5cba97c223 248 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 4.7E-114 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 WM46_RS07840 cf6117a2ce2fdbf435f7cc5cba97c223 248 Pfam PF00005 ABC transporter 17 172 4.8E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07840 cf6117a2ce2fdbf435f7cc5cba97c223 248 SMART SM00382 26 223 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07840 cf6117a2ce2fdbf435f7cc5cba97c223 248 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS16925 491066acee79aef17b59a1ae96153a2b 182 Gene3D G3DSA:2.60.450.10 27 164 9.9E-29 T 28-03-2018 WM46_RS16925 491066acee79aef17b59a1ae96153a2b 182 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 28 166 2.8E-52 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 WM46_RS16925 491066acee79aef17b59a1ae96153a2b 182 Pfam PF03968 OstA-like protein 37 149 1.8E-32 T 28-03-2018 IPR005653 Organic solvent tolerance-like, N-terminal WM46_RS16925 491066acee79aef17b59a1ae96153a2b 182 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 7 167 27.166 T 28-03-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 WM46_RS22630 48569647729da20971ee3f8a664468b9 227 Gene3D G3DSA:3.40.50.150 100 212 1.2E-8 T 28-03-2018 WM46_RS22630 48569647729da20971ee3f8a664468b9 227 SUPERFAMILY SSF53335 81 201 5.39E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS24305 052f5cfca8cb3e29412b119fa2e85d10 466 Pfam PF00860 Permease family 22 415 5.2E-109 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS24305 052f5cfca8cb3e29412b119fa2e85d10 466 TIGRFAM TIGR03173 pbuX: xanthine permease 28 447 8.9E-127 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 WM46_RS24305 052f5cfca8cb3e29412b119fa2e85d10 466 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 18 445 7.0E-138 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS24305 052f5cfca8cb3e29412b119fa2e85d10 466 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 363 383 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 89 97 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 Hamap MF_00258 Glutamate racemase [murI]. 22 274 34.456 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 Gene3D G3DSA:3.40.50.1860 140 273 1.2E-27 T 28-03-2018 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 Pfam PF01177 Asp/Glu/Hydantoin racemase 26 235 1.9E-24 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 200 210 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 SUPERFAMILY SSF53681 24 125 8.5E-31 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 TIGRFAM TIGR00067 glut_race: glutamate racemase 24 272 1.9E-92 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 SUPERFAMILY SSF53681 127 279 7.41E-33 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS21080 96c858b488f7ba5089bab9395e5ffe16 283 Gene3D G3DSA:3.40.50.1860 20 139 2.1E-26 T 28-03-2018 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 Pfam PF01578 Cytochrome C assembly protein 89 296 4.0E-55 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 2.9E-96 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 634 5.4E-298 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 624 637 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 8.5E-61 T 28-03-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02190 17a0035efbad3b399c3c321dfcb5f981 647 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 630 6.1E-124 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal WM46_RS02490 97151baefef957c6a1bcad6912e32588 231 Pfam PF04172 LrgB-like family 12 224 1.4E-78 T 28-03-2018 IPR007300 CidB/LrgB family WM46_RS02490 97151baefef957c6a1bcad6912e32588 231 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 2 226 6.1E-108 T 28-03-2018 IPR005261 Conserved hypothetical protein CHP00659 WM46_RS01895 e412b3c36744d71b587d092cb66e2902 300 SUPERFAMILY SSF88713 4 38 3.34E-26 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS01895 e412b3c36744d71b587d092cb66e2902 300 SUPERFAMILY SSF88713 82 280 3.34E-26 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS01895 e412b3c36744d71b587d092cb66e2902 300 Gene3D G3DSA:3.20.20.370 3 275 4.4E-27 T 28-03-2018 WM46_RS01895 e412b3c36744d71b587d092cb66e2902 300 Hamap MF_01870 Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD [arnD]. 1 295 62.626 T 28-03-2018 IPR023557 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD, probable GO:0016811 WM46_RS01895 e412b3c36744d71b587d092cb66e2902 300 Pfam PF01522 Polysaccharide deacetylase 15 158 5.2E-11 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 Pfam PF02274 Amidinotransferase 18 403 3.2E-105 T 28-03-2018 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 Gene3D G3DSA:3.75.10.10 5 404 1.3E-97 T 28-03-2018 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 Hamap MF_00242 Arginine deiminase [arcA]. 1 406 44.101 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 TIGRFAM TIGR01078 arcA: arginine deiminase 5 406 8.6E-160 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 SUPERFAMILY SSF55909 4 406 1.18E-132 T 28-03-2018 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PRINTS PR01466 Bacterial arginine deiminase signature 177 192 5.7E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PRINTS PR01466 Bacterial arginine deiminase signature 2 22 5.7E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PRINTS PR01466 Bacterial arginine deiminase signature 385 403 5.7E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PRINTS PR01466 Bacterial arginine deiminase signature 342 359 5.7E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PRINTS PR01466 Bacterial arginine deiminase signature 149 167 5.7E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PRINTS PR01466 Bacterial arginine deiminase signature 362 376 5.7E-44 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS23350 45dbc26bb80445fe7c66851722e0fb15 406 PIRSF PIRSF006356 1 406 3.9E-149 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 WM46_RS18955 685ce94859b99ec27bfe89ce3a3f62e7 443 Hamap MF_01279 Xaa-Pro dipeptidase [pepQ]. 1 443 58.007 T 28-03-2018 IPR022846 Xaa-Pro dipeptidase GO:0016795 WM46_RS18955 685ce94859b99ec27bfe89ce3a3f62e7 443 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 335 347 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site WM46_RS18955 685ce94859b99ec27bfe89ce3a3f62e7 443 SUPERFAMILY SSF55920 163 438 1.44E-56 T 28-03-2018 IPR000994 Peptidase M24 WM46_RS18955 685ce94859b99ec27bfe89ce3a3f62e7 443 Gene3D G3DSA:3.90.230.10 147 440 9.9E-54 T 28-03-2018 WM46_RS18955 685ce94859b99ec27bfe89ce3a3f62e7 443 Pfam PF00557 Metallopeptidase family M24 168 430 1.9E-46 T 28-03-2018 IPR000994 Peptidase M24 WM46_RS02775 a44c64fea0ee8de9c2ddc8be724dd919 617 Pfam PF13502 AsmA-like C-terminal region 357 570 7.4E-21 T 28-03-2018 IPR032712 AsmA-like, C-terminal WM46_RS02775 a44c64fea0ee8de9c2ddc8be724dd919 617 Pfam PF05170 AsmA family 3 271 7.0E-17 T 28-03-2018 IPR007844 AsmA WM46_RS23825 5c90dc60f6ffa6d84993939c055cdb1c 363 Gene3D G3DSA:3.40.50.720 188 329 1.2E-28 T 28-03-2018 WM46_RS23825 5c90dc60f6ffa6d84993939c055cdb1c 363 SUPERFAMILY SSF51735 166 324 4.83E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23825 5c90dc60f6ffa6d84993939c055cdb1c 363 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 45 157 3.8E-30 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS23825 5c90dc60f6ffa6d84993939c055cdb1c 363 SUPERFAMILY SSF50129 21 197 7.23E-44 T 28-03-2018 IPR011032 GroES-like WM46_RS23825 5c90dc60f6ffa6d84993939c055cdb1c 363 Pfam PF00107 Zinc-binding dehydrogenase 198 322 1.1E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS23825 5c90dc60f6ffa6d84993939c055cdb1c 363 Gene3D G3DSA:3.90.180.10 13 187 3.5E-40 T 28-03-2018 WM46_RS03985 46924217dc78c0da074603c69ffdc849 623 Pfam PF07510 Protein of unknown function (DUF1524) 428 592 7.2E-21 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 WM46_RS03985 46924217dc78c0da074603c69ffdc849 623 Pfam PF03235 Protein of unknown function DUF262 14 231 5.0E-37 T 28-03-2018 IPR004919 Domain of unknown function DUF262 WM46_RS07795 2f790595befe3c2b85029962a94c8c4c 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 222 1.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07795 2f790595befe3c2b85029962a94c8c4c 222 Gene3D G3DSA:1.10.3720.10 9 222 6.3E-33 T 28-03-2018 WM46_RS07795 2f790595befe3c2b85029962a94c8c4c 222 SUPERFAMILY SSF161098 11 209 2.75E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20565 3139cfdb0d9e5feef6fd683a719c79a6 233 Gene3D G3DSA:2.40.128.130 39 233 8.3E-11 T 28-03-2018 WM46_RS20565 3139cfdb0d9e5feef6fd683a719c79a6 233 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 90 233 1.4E-4 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS20565 3139cfdb0d9e5feef6fd683a719c79a6 233 Pfam PF03797 Autotransporter beta-domain 90 210 1.8E-10 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS20565 3139cfdb0d9e5feef6fd683a719c79a6 233 SUPERFAMILY SSF103515 84 233 1.83E-10 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS00435 26ec3faa5f1a5b217d4566848b3c9ce2 282 SUPERFAMILY SSF53697 103 279 2.86E-35 T 28-03-2018 WM46_RS00435 26ec3faa5f1a5b217d4566848b3c9ce2 282 SUPERFAMILY SSF46689 1 77 3.4E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS00435 26ec3faa5f1a5b217d4566848b3c9ce2 282 Gene3D G3DSA:3.40.50.10490 81 275 3.0E-33 T 28-03-2018 WM46_RS00435 26ec3faa5f1a5b217d4566848b3c9ce2 282 Pfam PF01380 SIS domain 128 257 2.8E-29 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS00435 26ec3faa5f1a5b217d4566848b3c9ce2 282 Gene3D G3DSA:1.10.10.10 1 77 2.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS00435 26ec3faa5f1a5b217d4566848b3c9ce2 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 74 1.9E-26 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS25655 f9b4e540b2537cdd77e299c18230dd54 81 SUPERFAMILY SSF52833 1 74 3.16E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS25655 f9b4e540b2537cdd77e299c18230dd54 81 Pfam PF00462 Glutaredoxin 3 58 2.3E-12 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM46_RS25655 f9b4e540b2537cdd77e299c18230dd54 81 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 3 73 2.5E-34 T 28-03-2018 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 WM46_RS25655 f9b4e540b2537cdd77e299c18230dd54 81 Gene3D G3DSA:3.40.30.10 1 77 2.4E-12 T 28-03-2018 WM46_RS10255 9445221afc0616f9ee51b433eaee29f8 375 Pfam PF07995 Glucose / Sorbosone dehydrogenase 34 366 3.8E-132 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase WM46_RS10255 9445221afc0616f9ee51b433eaee29f8 375 Gene3D G3DSA:2.120.10.30 18 271 1.1E-46 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM46_RS10255 9445221afc0616f9ee51b433eaee29f8 375 Gene3D G3DSA:2.120.10.30 272 363 6.4E-17 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM46_RS10255 9445221afc0616f9ee51b433eaee29f8 375 SUPERFAMILY SSF50952 23 370 3.4E-45 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 Gene3D G3DSA:2.40.230.20 26 294 8.5E-79 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 89 110 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 150 175 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 55 79 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 182 205 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 115 135 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 240 259 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 28 50 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 PRINTS PR01277 Nucleoside-specific channel-forming protein Tsx signature 270 293 2.4E-114 T 28-03-2018 IPR003055 Nucleoside-specific channel-forming protein, Tsx GO:0005337|GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 32 294 2.9E-81 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS12790 0cc4c2d9092466d66d9309b449e4046c 294 SUPERFAMILY SSF111364 32 294 4.05E-89 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS17995 9eca4961c6e14a88bee3aea4ebbe7342 571 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS17995 9eca4961c6e14a88bee3aea4ebbe7342 571 SUPERFAMILY SSF143975 10 378 7.32E-111 T 28-03-2018 WM46_RS17995 9eca4961c6e14a88bee3aea4ebbe7342 571 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 469 480 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS17995 9eca4961c6e14a88bee3aea4ebbe7342 571 SUPERFAMILY SSF52016 382 570 6.2E-53 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS17995 9eca4961c6e14a88bee3aea4ebbe7342 571 Pfam PF00920 Dehydratase family 33 568 3.3E-172 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.1E-41 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.6E-100 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 Pfam PF07650 KH domain 38 111 1.1E-18 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 Gene3D G3DSA:3.30.300.20 17 107 9.1E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 SMART SM00322 60 125 1.6E-6 T 28-03-2018 IPR004087 K Homology domain GO:0003676 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 SUPERFAMILY SSF54814 2 106 1.6E-37 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.15 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 Gene3D G3DSA:3.30.1140.32 108 207 3.4E-40 T 28-03-2018 WM46_RS17515 015d00c9b7f7f2897a9ebd700c9a9d69 233 SUPERFAMILY SSF54821 108 206 6.93E-41 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 SUPERFAMILY SSF111369 79 313 2.88E-53 T 28-03-2018 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 Gene3D G3DSA:2.40.50.100 191 399 1.3E-5 T 28-03-2018 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 Hamap MF_01422 Multidrug resistance protein MdtA [mdtA]. 1 413 53.863 T 28-03-2018 IPR022824 Multidrug resistance protein MdtA WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 Pfam PF13437 HlyD family secretion protein 198 301 2.7E-8 T 28-03-2018 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 Gene3D G3DSA:2.40.50.100 56 119 3.9E-8 T 28-03-2018 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 Pfam PF13533 Biotin-lipoyl like 87 132 3.6E-14 T 28-03-2018 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 62 390 6.5E-77 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS02745 b0f312ebf337818e98f07d1dc656ec2c 415 Gene3D G3DSA:1.10.287.470 128 190 4.8E-12 T 28-03-2018 WM46_RS25990 2b129de7ba3cf9cc1b6fdd1978b1d890 866 SUPERFAMILY SSF52540 437 785 1.72E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25990 2b129de7ba3cf9cc1b6fdd1978b1d890 866 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 232 863 8.4E-231 T 28-03-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 WM46_RS25990 2b129de7ba3cf9cc1b6fdd1978b1d890 866 Gene3D G3DSA:3.40.50.300 187 805 8.8E-17 T 28-03-2018 WM46_RS25990 2b129de7ba3cf9cc1b6fdd1978b1d890 866 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 232 429 2.0E-31 T 28-03-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 SUPERFAMILY SSF46785 3 77 1.18E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 60.402 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 153 2.0E-30 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 Gene3D G3DSA:3.30.1360.40 76 151 2.7E-26 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 Pfam PF02863 Arginine repressor, C-terminal domain 82 148 1.4E-22 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 Gene3D G3DSA:1.10.10.10 5 69 7.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 PRINTS PR01467 Bacterial arginine repressor signature 90 103 9.6E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 PRINTS PR01467 Bacterial arginine repressor signature 42 57 9.6E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 9.6E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 PRINTS PR01467 Bacterial arginine repressor signature 25 38 9.6E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 SUPERFAMILY SSF55252 82 151 1.57E-19 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 TIGRFAM TIGR01529 argR_whole: arginine repressor 9 152 1.5E-47 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 WM46_RS17085 a02b8cd42278288aee5d2c84bdad9e7d 156 Pfam PF01316 Arginine repressor, DNA binding domain 5 74 2.0E-25 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 SUPERFAMILY SSF52540 135 345 2.22E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 468 34.443 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 378 446 1.3E-32 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Pfam PF00308 Bacterial dnaA protein 135 351 4.0E-99 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 SUPERFAMILY SSF48295 365 468 4.45E-38 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Gene3D G3DSA:1.10.8.60 300 371 7.1E-28 T 28-03-2018 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Pfam PF11638 DnaA N-terminal domain 4 64 2.0E-20 T 28-03-2018 IPR024633 DnaA N-terminal domain WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 ProSitePatterns PS01008 DnaA protein signature. 427 446 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 427 446 1.7E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 265 292 1.7E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 167 187 1.7E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 231 245 1.7E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 199 213 1.7E-54 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Gene3D G3DSA:3.40.50.300 131 298 1.7E-21 T 28-03-2018 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 SMART SM00382 166 368 4.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 SMART SM00760 377 446 6.7E-45 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 467 2.3E-187 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 WM46_RS19650 5b5af80806f05ac783212c47e46071ff 469 Gene3D G3DSA:1.10.1750.10 372 468 2.5E-36 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 WM46_RS06115 0af6c4440d272b2886388f500bbb8705 168 SUPERFAMILY SSF52833 4 164 7.77E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS06115 0af6c4440d272b2886388f500bbb8705 168 ProSitePatterns PS01265 Tpx family signature. 84 95 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 WM46_RS06115 0af6c4440d272b2886388f500bbb8705 168 Pfam PF08534 Redoxin 20 163 1.6E-29 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 WM46_RS06115 0af6c4440d272b2886388f500bbb8705 168 Hamap MF_00269 Probable thiol peroxidase [tpx]. 4 167 38.847 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 WM46_RS06115 0af6c4440d272b2886388f500bbb8705 168 Gene3D G3DSA:3.40.30.10 6 168 1.4E-23 T 28-03-2018 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 4.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 4.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 Gene3D G3DSA:1.10.10.60 1 49 9.4E-17 T 28-03-2018 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 Gene3D G3DSA:1.10.10.60 50 151 3.2E-10 T 28-03-2018 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 201 4.9E-45 T 28-03-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 SUPERFAMILY SSF46689 2 65 1.85E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS17265 29ba846e41ccb132466cf2c0ddf55529 215 SUPERFAMILY SSF48498 84 202 4.62E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS12900 150b7ef21f1d9d4670ed467dd398f21a 457 Pfam PF00324 Amino acid permease 15 452 3.9E-107 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS12900 150b7ef21f1d9d4670ed467dd398f21a 457 PIRSF PIRSF006060 1 454 1.2E-77 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS12900 150b7ef21f1d9d4670ed467dd398f21a 457 ProSitePatterns PS00218 Amino acid permeases signature. 40 70 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS13270 22438ec7753d4bf231968a6d7d31f95c 338 Gene3D G3DSA:3.40.50.1980 165 335 4.1E-31 T 28-03-2018 WM46_RS13270 22438ec7753d4bf231968a6d7d31f95c 338 Pfam PF01497 Periplasmic binding protein 45 310 2.6E-33 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS13270 22438ec7753d4bf231968a6d7d31f95c 338 SUPERFAMILY SSF53807 42 330 3.1E-38 T 28-03-2018 WM46_RS13270 22438ec7753d4bf231968a6d7d31f95c 338 Gene3D G3DSA:3.40.50.1980 24 164 2.3E-25 T 28-03-2018 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 Gene3D G3DSA:2.40.50.180 45 108 3.0E-10 T 28-03-2018 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 Gene3D G3DSA:2.30.30.40 109 147 3.9E-5 T 28-03-2018 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 Gene3D G3DSA:3.40.50.2300 180 331 1.1E-21 T 28-03-2018 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 SMART SM00448 187 312 2.2E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 SMART SM00260 17 161 2.9E-13 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 Pfam PF01584 CheW-like domain 22 163 4.1E-30 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 PIRSF PIRSF002867 1 320 8.1E-106 T 28-03-2018 IPR024181 Chemotaxis response regulator CheV WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 SUPERFAMILY SSF50341 18 165 2.35E-24 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 Pfam PF00072 Response regulator receiver domain 190 311 1.9E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS01825 2c398b1ac345625b8d42d8a946a5d32b 334 SUPERFAMILY SSF52172 189 320 4.13E-21 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS20960 f38e292e99c005354a97561f35fbd2c1 765 Gene3D G3DSA:3.20.70.20 1 765 6.6E-266 T 28-03-2018 WM46_RS20960 f38e292e99c005354a97561f35fbd2c1 765 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 1 765 0.0 T 28-03-2018 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS20960 f38e292e99c005354a97561f35fbd2c1 765 Pfam PF02901 Pyruvate formate lyase-like 3 626 3.7E-197 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 WM46_RS20960 f38e292e99c005354a97561f35fbd2c1 765 SUPERFAMILY SSF51998 3 764 1.6E-212 T 28-03-2018 WM46_RS20960 f38e292e99c005354a97561f35fbd2c1 765 ProSitePatterns PS00850 Glycine radical domain signature. 736 744 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site WM46_RS20960 f38e292e99c005354a97561f35fbd2c1 765 Pfam PF01228 Glycine radical 646 747 5.0E-25 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 WM46_RS15905 1b6e96b100cf9a4a94b72345f38d3e50 350 Pfam PF01497 Periplasmic binding protein 44 297 2.8E-30 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS15905 1b6e96b100cf9a4a94b72345f38d3e50 350 Gene3D G3DSA:3.40.50.1980 23 181 8.7E-26 T 28-03-2018 WM46_RS15905 1b6e96b100cf9a4a94b72345f38d3e50 350 SUPERFAMILY SSF53807 28 347 1.49E-57 T 28-03-2018 WM46_RS15905 1b6e96b100cf9a4a94b72345f38d3e50 350 Gene3D G3DSA:3.40.50.1980 189 349 1.0E-42 T 28-03-2018 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 SUPERFAMILY SSF109604 339 511 1.88E-16 T 28-03-2018 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 Gene3D G3DSA:1.10.730.10 574 683 3.5E-9 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 318 334 5.3E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 5.3E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 5.3E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 246 261 5.3E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 5.3E-37 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 688 27.04 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 551 7.3E-215 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 Pfam PF05746 DALR anticodon binding domain 582 679 4.0E-7 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 WM46_RS20490 f03ab51d8a228f803265261c41f3dc81 689 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 689 0.0 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 Gene3D G3DSA:1.10.150.240 30 76 5.6E-16 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 1.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 1.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 1.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 1.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 SUPERFAMILY SSF56784 10 209 2.94E-45 T 28-03-2018 IPR023214 HAD-like domain WM46_RS01735 39a14853b8560178699d6043e1765f22 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 12 187 1.1E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS01735 39a14853b8560178699d6043e1765f22 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 187 7.7E-26 T 28-03-2018 IPR023214 HAD-like domain WM46_RS01735 39a14853b8560178699d6043e1765f22 225 Gene3D G3DSA:3.40.50.1000 77 215 6.1E-27 T 28-03-2018 IPR023214 HAD-like domain WM46_RS01735 39a14853b8560178699d6043e1765f22 225 Gene3D G3DSA:3.40.50.1000 1 29 0.14 T 28-03-2018 IPR023214 HAD-like domain WM46_RS18750 405ecef770000555d68043a70eac734d 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 2.9E-53 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 WM46_RS18750 405ecef770000555d68043a70eac734d 145 Gene3D G3DSA:3.50.80.10 1 145 5.3E-54 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain WM46_RS18750 405ecef770000555d68043a70eac734d 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 5.5E-74 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 WM46_RS18750 405ecef770000555d68043a70eac734d 145 SUPERFAMILY SSF69500 1 144 1.05E-55 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain WM46_RS18750 405ecef770000555d68043a70eac734d 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.554 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 Gene3D G3DSA:3.90.1150.10 372 484 1.6E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 Gene3D G3DSA:3.40.640.10 123 371 3.9E-84 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 PIRSF PIRSF000521 87 208 1.8E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 PIRSF PIRSF000521 197 484 4.6E-43 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 300 337 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 TIGRFAM TIGR03372 putres_am_tran: putrescine aminotransferase 40 481 1.7E-290 T 28-03-2018 IPR017747 Putrescine aminotransferase GO:0009447|GO:0030170|GO:0033094 KEGG: 00330+2.6.1.82|MetaCyc: PWY-2|MetaCyc: PWY-6440 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 Pfam PF00202 Aminotransferase class-III 106 481 1.9E-103 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 Hamap MF_01276 Putrescine aminotransferase [patA]. 33 491 88.577 T 28-03-2018 IPR017747 Putrescine aminotransferase GO:0009447|GO:0030170|GO:0033094 KEGG: 00330+2.6.1.82|MetaCyc: PWY-2|MetaCyc: PWY-6440 WM46_RS16350 ee54eae57773d3a5dda56aadbebc4d7c 491 SUPERFAMILY SSF53383 103 482 1.53E-119 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS17970 5514af9068e126f05e4c30f301b36b9c 276 SUPERFAMILY SSF144091 92 267 6.8E-45 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 WM46_RS17970 5514af9068e126f05e4c30f301b36b9c 276 Hamap MF_01594 Rhomboid protease GlpG [glpG]. 1 274 45.323 T 28-03-2018 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 WM46_RS17970 5514af9068e126f05e4c30f301b36b9c 276 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 1 82 1.0E-28 T 28-03-2018 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 WM46_RS17970 5514af9068e126f05e4c30f301b36b9c 276 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 4 269 2.7E-116 T 28-03-2018 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 WM46_RS17970 5514af9068e126f05e4c30f301b36b9c 276 Gene3D G3DSA:1.20.1540.10 91 268 5.4E-38 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 WM46_RS17970 5514af9068e126f05e4c30f301b36b9c 276 Pfam PF01694 Rhomboid family 132 267 5.2E-29 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 WM46_RS18460 c65d4e8a355f5ec076233aebc2f050f4 255 Pfam PF00121 Triosephosphate isomerase 5 246 1.2E-93 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS18460 c65d4e8a355f5ec076233aebc2f050f4 255 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS18460 c65d4e8a355f5ec076233aebc2f050f4 255 SUPERFAMILY SSF51351 1 248 5.11E-91 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS18460 c65d4e8a355f5ec076233aebc2f050f4 255 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 40.63 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS18460 c65d4e8a355f5ec076233aebc2f050f4 255 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 7.1E-105 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 WM46_RS18460 c65d4e8a355f5ec076233aebc2f050f4 255 Gene3D G3DSA:3.20.20.70 1 255 2.3E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS13045 7702ce4e123dfd1dba5abfdf4877f658 207 SUPERFAMILY SSF51206 23 125 7.63E-5 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like WM46_RS13045 7702ce4e123dfd1dba5abfdf4877f658 207 Hamap MF_02072 Inhibitor of hydrogen peroxide resistance [iprA]. 1 207 44.895 T 28-03-2018 IPR034719 Inhibitor of hydrogen peroxide resistance WM46_RS13045 7702ce4e123dfd1dba5abfdf4877f658 207 Gene3D G3DSA:1.10.10.10 134 200 6.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13045 7702ce4e123dfd1dba5abfdf4877f658 207 Pfam PF15977 Winged helix-turn-helix DNA binding 138 205 1.9E-27 T 28-03-2018 WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 Gene3D G3DSA:1.25.40.10 114 140 2.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 Gene3D G3DSA:2.40.70.10 344 476 6.7E-5 T 28-03-2018 IPR021109 Aspartic peptidase domain WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 Gene3D G3DSA:2.40.70.10 196 331 5.6E-18 T 28-03-2018 IPR021109 Aspartic peptidase domain WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 SUPERFAMILY SSF48452 63 154 4.64E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 SUPERFAMILY SSF50630 192 273 1.25E-11 T 28-03-2018 IPR021109 Aspartic peptidase domain WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 Pfam PF13650 Aspartyl protease 203 299 9.0E-16 T 28-03-2018 WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 Gene3D G3DSA:1.25.40.10 141 177 0.34 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS09485 c7f24821bc620462ebd7d84c0937d5ef 476 Gene3D G3DSA:1.25.40.10 21 113 2.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 SUPERFAMILY SSF51395 223 375 4.52E-99 T 28-03-2018 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 SUPERFAMILY SSF51395 6 193 4.52E-99 T 28-03-2018 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 PIRSF PIRSF000138 2 380 1.9E-121 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 Pfam PF01070 FMN-dependent dehydrogenase 13 375 1.1E-124 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 1 380 73.902 T 28-03-2018 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 WM46_RS20300 8e569c69608d317cce6c8fd4cff99259 395 Gene3D G3DSA:3.20.20.70 2 380 1.3E-96 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS20525 5182e7aa0946196d82e2fd03ce8dc4b8 426 Pfam PF07690 Major Facilitator Superfamily 269 416 4.1E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20525 5182e7aa0946196d82e2fd03ce8dc4b8 426 Pfam PF07690 Major Facilitator Superfamily 18 258 1.3E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20525 5182e7aa0946196d82e2fd03ce8dc4b8 426 Gene3D G3DSA:1.20.1250.20 6 207 4.3E-32 T 28-03-2018 WM46_RS20525 5182e7aa0946196d82e2fd03ce8dc4b8 426 SUPERFAMILY SSF103473 8 415 3.66E-82 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20525 5182e7aa0946196d82e2fd03ce8dc4b8 426 PIRSF PIRSF002808 1 424 1.0E-33 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS20525 5182e7aa0946196d82e2fd03ce8dc4b8 426 Gene3D G3DSA:1.20.1250.20 221 419 5.4E-33 T 28-03-2018 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Gene3D G3DSA:3.40.1190.10 105 342 5.0E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 491 35.051 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Pfam PF08245 Mur ligase middle domain 114 318 1.1E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 425 1.4E-25 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Pfam PF01225 Mur ligase family, catalytic domain 24 102 5.7E-12 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 491 3.5E-166 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 SUPERFAMILY SSF63418 5 103 8.63E-23 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Gene3D G3DSA:3.90.190.20 343 494 3.7E-49 T 28-03-2018 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 Gene3D G3DSA:3.40.1390.10 2 104 5.7E-24 T 28-03-2018 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 SUPERFAMILY SSF53244 339 491 6.26E-51 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14405 4ae307f66b8237da81dcea60f92f999f 495 SUPERFAMILY SSF53623 105 338 4.32E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 280 293 1.4E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 97 113 1.4E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 226 240 1.4E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 SUPERFAMILY SSF53335 96 460 5.11E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 178 190 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 Gene3D G3DSA:3.90.120.10 313 447 3.0E-25 T 28-03-2018 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 Gene3D G3DSA:3.40.50.150 87 309 2.0E-56 T 28-03-2018 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 441 459 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 Pfam PF00145 C-5 cytosine-specific DNA methylase 96 457 7.4E-77 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS25930 cab7c90631a53c22f1765b6230674006 477 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 98 459 3.6E-115 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 5 452 43.073 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Pfam PF12804 MobA-like NTP transferase domain 8 122 4.0E-19 T 28-03-2018 IPR025877 MobA-like NTP transferase WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 1.1E-6 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 6.0E-8 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 353 382 0.0029 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS19535 3a9697b739b94759e516880683268e1f 456 SUPERFAMILY SSF51161 255 439 7.16E-53 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS19535 3a9697b739b94759e516880683268e1f 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 455 2.5E-206 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Gene3D G3DSA:2.160.10.10 319 440 5.2E-35 T 28-03-2018 WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Gene3D G3DSA:2.160.10.10 245 318 2.4E-18 T 28-03-2018 WM46_RS19535 3a9697b739b94759e516880683268e1f 456 Gene3D G3DSA:3.90.550.10 3 244 3.5E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS19535 3a9697b739b94759e516880683268e1f 456 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS19535 3a9697b739b94759e516880683268e1f 456 SUPERFAMILY SSF53448 6 252 1.79E-66 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 SMART SM00382 29 216 2.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 SUPERFAMILY SSF52540 4 247 3.42E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 Gene3D G3DSA:2.40.50.140 289 352 3.1E-15 T 28-03-2018 WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 Pfam PF08402 TOBE domain 287 359 7.0E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 SUPERFAMILY SSF50331 242 367 2.34E-20 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 Gene3D G3DSA:3.40.50.300 2 250 1.1E-62 T 28-03-2018 WM46_RS16565 bc14cfe8e133dd62915f3680d020a5c2 370 Pfam PF00005 ABC transporter 21 161 9.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07690 a9a20ea85ac5ffe60fddc327af044761 265 SUPERFAMILY SSF56281 52 235 3.22E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS07690 a9a20ea85ac5ffe60fddc327af044761 265 SMART SM00849 72 223 0.0014 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS07690 a9a20ea85ac5ffe60fddc327af044761 265 Gene3D G3DSA:3.60.15.10 56 230 9.7E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 3 162 1.4E-81 T 28-03-2018 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 2 355 51.006 T 28-03-2018 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 167 355 37.756 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Pfam PF13242 HAD-hyrolase-like 103 145 8.3E-6 T 28-03-2018 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 SUPERFAMILY SSF54211 252 342 9.86E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 226 239 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 146 5.8E-25 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 196 337 3.5E-65 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Gene3D G3DSA:3.40.50.1000 1 164 1.9E-25 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 SUPERFAMILY SSF56784 1 158 5.47E-40 T 28-03-2018 IPR023214 HAD-like domain WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 319 331 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 144 1.4E-45 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Gene3D G3DSA:3.30.230.40 165 253 6.1E-34 T 28-03-2018 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 Gene3D G3DSA:3.30.230.40 255 355 1.1E-31 T 28-03-2018 WM46_RS03025 d98cd50c4eaf9ce4c713ad46db51284c 355 SUPERFAMILY SSF54211 167 251 1.39E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS11445 71c43fb641072187f669d073c0a078af 79 ProSitePatterns PS00352 'Cold-shock' domain signature. 27 46 - T 28-03-2018 IPR019844 Cold-shock conserved site WM46_RS11445 71c43fb641072187f669d073c0a078af 79 Gene3D G3DSA:2.40.50.140 13 79 1.7E-29 T 28-03-2018 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 PIRSF PIRSF002599 10 79 5.0E-27 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 PRINTS PR00050 Cold shock protein signature 37 46 2.2E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 PRINTS PR00050 Cold shock protein signature 16 31 2.2E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 PRINTS PR00050 Cold shock protein signature 52 70 2.2E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 Pfam PF00313 'Cold-shock' DNA-binding domain 15 78 1.2E-33 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 SMART SM00357 15 79 9.9E-34 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS11445 71c43fb641072187f669d073c0a078af 79 SUPERFAMILY SSF50249 10 78 3.0E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS06845 0425cf462c2ad3d42061c3f333c29a38 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 292 3.5E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06845 0425cf462c2ad3d42061c3f333c29a38 297 Gene3D G3DSA:1.10.3720.10 11 283 3.6E-40 T 28-03-2018 WM46_RS06845 0425cf462c2ad3d42061c3f333c29a38 297 SUPERFAMILY SSF161098 89 275 6.41E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06845 0425cf462c2ad3d42061c3f333c29a38 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 70 1.8E-8 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM46_RS05785 fb407fb73d9fb7186bd75bd16ffdd9f3 98 SUPERFAMILY SSF54909 2 98 6.26E-31 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS05785 fb407fb73d9fb7186bd75bd16ffdd9f3 98 Gene3D G3DSA:3.30.70.1060 1 98 7.9E-29 T 28-03-2018 WM46_RS05785 fb407fb73d9fb7186bd75bd16ffdd9f3 98 Pfam PF03795 YCII-related domain 2 95 9.7E-30 T 28-03-2018 IPR005545 YCII-related WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 ProSitePatterns PS00622 LuxR-type HTH domain signature. 152 179 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 Gene3D G3DSA:3.40.50.2300 1 122 1.4E-27 T 28-03-2018 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 SMART SM00448 2 112 2.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 SUPERFAMILY SSF46894 127 193 5.78E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 SMART SM00421 135 192 4.5E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 Gene3D G3DSA:1.10.10.10 123 195 2.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 SUPERFAMILY SSF52172 1 125 2.7E-27 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS19835 44f51aa18aa3e8bb52458489aef4ffbe 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 190 1.9E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13950 05c48df212d76201fc63e6326f5ded2d 252 SUPERFAMILY SSF64005 18 239 2.22E-87 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM46_RS13950 05c48df212d76201fc63e6326f5ded2d 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 189 206 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 WM46_RS13950 05c48df212d76201fc63e6326f5ded2d 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 243 5.9E-81 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM46_RS13950 05c48df212d76201fc63e6326f5ded2d 252 Gene3D G3DSA:3.40.1180.10 6 247 3.5E-91 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM46_RS13950 05c48df212d76201fc63e6326f5ded2d 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 244 39.835 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM46_RS13950 05c48df212d76201fc63e6326f5ded2d 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 18 243 1.8E-105 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 5 886 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 Gene3D G3DSA:3.40.50.920 707 887 1.3E-42 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 Gene3D G3DSA:3.40.50.970 57 471 2.3E-83 T 28-03-2018 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 SUPERFAMILY SSF52922 702 885 1.08E-63 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 106 294 4.7E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 SUPERFAMILY SSF52518 58 469 3.93E-143 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 PIRSF PIRSF000156 1 887 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 Gene3D G3DSA:3.40.50.970 472 706 5.3E-67 T 28-03-2018 WM46_RS14260 789913ebb511e21892576e640c7f5d2b 887 SUPERFAMILY SSF52518 474 701 2.47E-98 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 Pfam PF00990 Diguanylate cyclase, GGDEF domain 297 451 2.6E-49 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 Pfam PF11563 Protoglobin 20 154 1.1E-9 T 28-03-2018 WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 297 455 5.7E-53 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 SMART SM00267 283 456 3.5E-68 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 SUPERFAMILY SSF55073 300 457 4.79E-46 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 Gene3D G3DSA:3.30.70.270 288 460 8.8E-52 T 28-03-2018 WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 SUPERFAMILY SSF46458 7 151 3.64E-23 T 28-03-2018 IPR009050 Globin-like WM46_RS06885 4fe476ae062d7e2e30b1774be0150737 460 Gene3D G3DSA:1.10.490.10 6 152 1.3E-16 T 28-03-2018 WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 Gene3D G3DSA:3.40.190.10 92 178 2.5E-13 T 28-03-2018 WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 SUPERFAMILY SSF46785 7 90 5.99E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 Pfam PF03466 LysR substrate binding domain 91 294 5.4E-36 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 Gene3D G3DSA:3.40.190.10 179 267 4.6E-25 T 28-03-2018 WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 SUPERFAMILY SSF53850 93 299 7.24E-40 T 28-03-2018 WM46_RS05035 2a50804fd62a31ed98e67685e88042ba 305 Gene3D G3DSA:1.10.10.10 6 90 2.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Gene3D G3DSA:2.40.50.140 641 726 2.1E-21 T 28-03-2018 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SUPERFAMILY SSF50249 644 724 1.6E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Pfam PF00773 RNB domain 260 587 1.8E-110 T 28-03-2018 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SMART SM00955 260 588 7.2E-185 T 28-03-2018 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 TIGRFAM TIGR02063 RNase_R: ribonuclease R 19 725 2.7E-287 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SUPERFAMILY SSF50249 67 145 1.79E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Pfam PF08206 Ribonuclease B OB domain 87 144 4.3E-22 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Hamap MF_01895 Ribonuclease R [rnr]. 38 725 58.114 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SUPERFAMILY SSF50249 222 641 1.31E-142 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 67 725 5.0E-289 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SMART SM00316 642 725 3.0E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SUPERFAMILY SSF50249 138 235 2.29E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Pfam PF08461 Ribonuclease R winged-helix domain 23 85 2.3E-15 T 28-03-2018 IPR013668 Ribonuclease R winged-helix domain WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Pfam PF00575 S1 RNA binding domain 641 724 1.8E-20 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 ProSitePatterns PS01175 Ribonuclease II family signature. 555 579 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 Gene3D G3DSA:1.10.10.10 18 79 3.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22920 bf4a5838c9d990ff13fd486e6431aa85 812 SMART SM00357 86 145 2.1E-16 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 SUPERFAMILY SSF102114 127 372 1.83E-63 T 28-03-2018 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 Pfam PF04055 Radical SAM superfamily 151 325 4.8E-27 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 440 74.948 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 3.4E-158 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 1.1E-220 T 28-03-2018 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 SMART SM00729 147 367 1.8E-63 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 Gene3D G3DSA:3.40.50.280 39 127 0.32 T 28-03-2018 WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 Pfam PF01938 TRAM domain 378 440 2.5E-19 T 28-03-2018 IPR002792 TRAM domain WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 Gene3D G3DSA:3.80.30.20 144 381 1.3E-52 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe WM46_RS11295 8ca36ba16b4c1d890ffcdc7495144159 474 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 4.6E-29 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 WM46_RS17290 823ce3793d286e37925d44a16978bd6a 393 SUPERFAMILY SSF161098 84 158 1.7E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS17290 823ce3793d286e37925d44a16978bd6a 393 Gene3D G3DSA:1.10.3720.10 11 173 1.9E-20 T 28-03-2018 WM46_RS17290 823ce3793d286e37925d44a16978bd6a 393 Gene3D G3DSA:1.10.3720.10 177 393 5.7E-37 T 28-03-2018 WM46_RS17290 823ce3793d286e37925d44a16978bd6a 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 388 6.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS17290 823ce3793d286e37925d44a16978bd6a 393 SUPERFAMILY SSF161098 181 375 1.11E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS17290 823ce3793d286e37925d44a16978bd6a 393 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 84 147 1.0E-16 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 374 2.1E-121 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 SUPERFAMILY SSF56796 3 380 3.79E-126 T 28-03-2018 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 TIGRFAM TIGR02638 lactal_redase: lactaldehyde reductase 2 378 2.4E-180 T 28-03-2018 IPR013460 Lactaldehyde reductase KEGG: 00630+1.1.1.77|KEGG: 00640+1.1.1.77 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 259 279 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 Gene3D G3DSA:3.40.50.1970 8 182 4.4E-43 T 28-03-2018 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS18600 a8526274f2a52637176cf44db388db77 382 Gene3D G3DSA:1.20.1090.10 183 382 2.6E-67 T 28-03-2018 WM46_RS10335 6e2b96dd088027481356ce806128a050 433 Gene3D G3DSA:1.20.1250.20 13 214 4.7E-41 T 28-03-2018 WM46_RS10335 6e2b96dd088027481356ce806128a050 433 Gene3D G3DSA:1.20.1250.20 230 433 2.4E-20 T 28-03-2018 WM46_RS10335 6e2b96dd088027481356ce806128a050 433 SUPERFAMILY SSF103473 13 431 1.57E-78 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS10335 6e2b96dd088027481356ce806128a050 433 Pfam PF07690 Major Facilitator Superfamily 30 390 9.5E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Hamap MF_01449 HTH-type transcriptional regulator SgrR [sgrR]. 1 551 65.14 T 28-03-2018 IPR023767 Transcriptional regulator SgrR WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 165 306 1.1E-17 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Pfam PF12793 Sugar transport-related sRNA regulator N-term 5 118 3.7E-42 T 28-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 SUPERFAMILY SSF53850 121 546 8.14E-63 T 28-03-2018 WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Gene3D G3DSA:3.40.190.10 256 313 1.4E-5 T 28-03-2018 WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 SUPERFAMILY SSF46785 22 68 5.71E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Gene3D G3DSA:3.90.76.10 129 255 4.0E-21 T 28-03-2018 WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Gene3D G3DSA:3.10.105.10 321 470 0.13 T 28-03-2018 WM46_RS14485 9a9432229fe5763025b11fe50a0e35ba 551 Gene3D G3DSA:1.10.10.10 7 89 4.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16125 29b3c022682aa15b2d5c1b00ac456cef 210 SUPERFAMILY SSF55811 5 208 3.66E-52 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS16125 29b3c022682aa15b2d5c1b00ac456cef 210 Pfam PF00293 NUDIX domain 59 179 1.7E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS16125 29b3c022682aa15b2d5c1b00ac456cef 210 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 14 199 7.4E-84 T 28-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 WM46_RS16125 29b3c022682aa15b2d5c1b00ac456cef 210 ProSitePatterns PS00893 Nudix box signature. 97 118 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS16125 29b3c022682aa15b2d5c1b00ac456cef 210 Gene3D G3DSA:3.90.79.10 1 209 3.1E-46 T 28-03-2018 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 204 1.7E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Gene3D G3DSA:3.40.50.720 252 490 2.7E-53 T 28-03-2018 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 SUPERFAMILY SSF48179 614 706 1.53E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 SUPERFAMILY SSF51735 309 489 2.3E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Hamap MF_01617 Fatty acid oxidation complex subunit alpha [fadJ]. 1 706 53.183 T 28-03-2018 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Gene3D G3DSA:3.90.226.10 2 205 4.9E-59 T 28-03-2018 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 492 586 5.2E-28 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 SUPERFAMILY SSF52096 6 298 2.57E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 TIGRFAM TIGR02440 FadJ: fatty oxidation complex, alpha subunit FadJ 6 706 0.0 T 28-03-2018 IPR012802 Fatty oxidation complex, alpha subunit FadJ GO:0003857|GO:0004300|GO:0006635|GO:0008692|GO:0051287|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 489 513 - T 28-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 311 489 2.0E-58 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 SUPERFAMILY SSF48179 492 595 4.76E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Gene3D G3DSA:1.10.1040.10 613 710 2.1E-18 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS01485 c211b57aed6a7423edce0f4aa0b81e11 719 Gene3D G3DSA:1.10.1040.10 491 591 8.0E-25 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS09540 8e82821461793f0cfbe6f28ba4107c41 132 Gene3D G3DSA:3.10.180.10 1 132 2.8E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS09540 8e82821461793f0cfbe6f28ba4107c41 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 109 3.5E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM46_RS09540 8e82821461793f0cfbe6f28ba4107c41 132 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 WM46_RS09540 8e82821461793f0cfbe6f28ba4107c41 132 SUPERFAMILY SSF54593 1 120 5.5E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS16400 0fe571e71b8a782f0e4989f017a244b2 470 Hamap MF_00675 Uronate isomerase [uxaC]. 2 467 50.447 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 WM46_RS16400 0fe571e71b8a782f0e4989f017a244b2 470 Gene3D G3DSA:3.20.20.140 3 88 3.2E-28 T 28-03-2018 WM46_RS16400 0fe571e71b8a782f0e4989f017a244b2 470 Pfam PF02614 Glucuronate isomerase 1 465 6.5E-231 T 28-03-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 WM46_RS16400 0fe571e71b8a782f0e4989f017a244b2 470 Gene3D G3DSA:3.20.20.140 89 467 8.1E-155 T 28-03-2018 WM46_RS16400 0fe571e71b8a782f0e4989f017a244b2 470 SUPERFAMILY SSF51556 3 465 2.72E-183 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS03385 85bf8848915547d8ed82ce2ecf82e9c0 197 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 77 194 2.0E-21 T 28-03-2018 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly WM46_RS11435 3bd76a0ae22558f8ed0b8b2e9c81b973 262 Gene3D G3DSA:3.60.110.10 1 257 3.4E-57 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS11435 3bd76a0ae22558f8ed0b8b2e9c81b973 262 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site WM46_RS11435 3bd76a0ae22558f8ed0b8b2e9c81b973 262 Pfam PF00795 Carbon-nitrogen hydrolase 3 245 8.9E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS11435 3bd76a0ae22558f8ed0b8b2e9c81b973 262 SUPERFAMILY SSF56317 1 254 8.89E-59 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS05510 9dd52ed5f802ca6607c828ebf1fca40f 355 Gene3D G3DSA:1.10.3470.10 15 355 3.5E-68 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS05510 9dd52ed5f802ca6607c828ebf1fca40f 355 Pfam PF01032 FecCD transport family 32 350 2.5E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS05510 9dd52ed5f802ca6607c828ebf1fca40f 355 SUPERFAMILY SSF81345 20 350 2.62E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS02930 93e8259cde343d5a8fe3a558cd27a729 299 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.3E-150 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 WM46_RS02930 93e8259cde343d5a8fe3a558cd27a729 299 Gene3D G3DSA:3.90.550.10 1 297 1.2E-70 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02930 93e8259cde343d5a8fe3a558cd27a729 299 Pfam PF00483 Nucleotidyl transferase 2 238 3.5E-69 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM46_RS02930 93e8259cde343d5a8fe3a558cd27a729 299 SUPERFAMILY SSF53448 1 287 3.38E-90 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 Pfam PF00155 Aminotransferase class I and II 142 451 4.0E-25 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 Gene3D G3DSA:3.90.1150.10 369 462 2.8E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 SUPERFAMILY SSF46785 21 98 4.59E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 Gene3D G3DSA:1.10.10.10 17 91 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 SMART SM00345 31 90 1.2E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 90 2.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 1.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 1.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 SUPERFAMILY SSF53383 101 460 4.41E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS12485 8c0f830a53ff7254119023bf0f1408b9 475 Gene3D G3DSA:3.40.640.10 119 368 2.7E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 53 152 3.9E-15 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 Gene3D G3DSA:3.30.1330.10 1 156 5.5E-23 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 SUPERFAMILY SSF56042 163 331 3.44E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 Gene3D G3DSA:3.90.650.10 161 324 8.6E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 166 313 1.1E-24 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 SUPERFAMILY SSF55326 3 156 3.31E-32 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 PIRSF PIRSF005644 1 336 1.3E-119 T 28-03-2018 IPR011854 Hydrogenase expression/formation protein HypE WM46_RS25360 c4e0540107403abdd638ac4cb255c217 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 336 3.1E-138 T 28-03-2018 IPR011854 Hydrogenase expression/formation protein HypE WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 Gene3D G3DSA:3.40.50.20 1 150 3.7E-43 T 28-03-2018 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 350 4.8E-119 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 293 321 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 SUPERFAMILY SSF52440 3 139 7.19E-36 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 Gene3D G3DSA:3.30.470.20 214 360 2.9E-44 T 28-03-2018 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 Pfam PF01820 D-ala D-ala ligase N-terminus 5 130 3.2E-29 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 PIRSF PIRSF039102 1 359 3.3E-138 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 351 42.874 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 107 118 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 Gene3D G3DSA:3.30.1490.20 155 213 1.6E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 SUPERFAMILY SSF56059 140 354 1.48E-62 T 28-03-2018 WM46_RS13005 a2d966db50cd9281e5f9c05ff98ac0a0 364 Pfam PF07478 D-ala D-ala ligase C-terminus 147 348 1.5E-82 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 SUPERFAMILY SSF51735 4 251 7.02E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 Gene3D G3DSA:3.40.50.720 1 38 3.2E-6 T 28-03-2018 WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 Gene3D G3DSA:3.40.50.720 39 252 3.0E-59 T 28-03-2018 WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 0.0056 T 28-03-2018 WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 250 3.4E-55 T 28-03-2018 WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 9.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 9.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 9.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS20735 c2d306f0847028917d485fd2655b35c9 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 51 72 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 78 92 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 158 172 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 269 288 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 219 238 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 181 200 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 314 340 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 94 107 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 35 51 5.1E-74 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 SUPERFAMILY SSF53850 29 369 1.37E-104 T 28-03-2018 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 Pfam PF13416 Bacterial extracellular solute-binding protein 46 335 2.7E-34 T 28-03-2018 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 PIRSF PIRSF019574 1 370 8.4E-144 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 Gene3D G3DSA:3.40.190.10 200 333 4.5E-20 T 28-03-2018 WM46_RS10160 d08d40a88cbf273d811e579e5083050a 370 Gene3D G3DSA:3.40.190.10 23 199 1.2E-33 T 28-03-2018 WM46_RS19900 dd474dc9b8bae0623805e5f622b244a0 443 PIRSF PIRSF006351 5 437 1.0E-134 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS19900 dd474dc9b8bae0623805e5f622b244a0 443 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 16 426 8.5E-111 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 WM46_RS19900 dd474dc9b8bae0623805e5f622b244a0 443 Pfam PF02378 Phosphotransferase system, EIIC 33 352 3.4E-49 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS06330 6b133ffe9379897f7cc9aa238ac022d3 458 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 455 7.6E-114 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 WM46_RS06330 6b133ffe9379897f7cc9aa238ac022d3 458 Gene3D G3DSA:1.20.1600.10 20 458 2.8E-95 T 28-03-2018 WM46_RS06330 6b133ffe9379897f7cc9aa238ac022d3 458 Pfam PF02321 Outer membrane efflux protein 268 453 2.1E-23 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS06330 6b133ffe9379897f7cc9aa238ac022d3 458 Pfam PF02321 Outer membrane efflux protein 59 246 2.1E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS06330 6b133ffe9379897f7cc9aa238ac022d3 458 SUPERFAMILY SSF56954 2 456 1.26E-105 T 28-03-2018 WM46_RS05605 b8718bfd9753a80bbabdb50c34ba5b1c 471 Pfam PF11924 Inverse autotransporter, beta-domain 81 344 2.0E-100 T 28-03-2018 IPR024519 Inverse autotransporter, beta-domain WM46_RS24620 7089a7ba3734a3b0d6454a2651c5c66a 182 SUPERFAMILY SSF49401 32 182 1.24E-37 T 28-03-2018 IPR008966 Adhesion domain WM46_RS24620 7089a7ba3734a3b0d6454a2651c5c66a 182 Gene3D G3DSA:2.60.40.1090 31 182 2.8E-39 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24620 7089a7ba3734a3b0d6454a2651c5c66a 182 Pfam PF00419 Fimbrial protein 33 182 5.9E-23 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 Pfam PF04060 Putative Fe-S cluster 44 76 9.4E-13 T 28-03-2018 IPR007202 4Fe-4S domain GO:0051536 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 Gene3D G3DSA:3.30.70.20 24 125 9.2E-11 T 28-03-2018 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 Gene3D G3DSA:3.30.70.20 126 147 1.5E-11 T 28-03-2018 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 PIRSF PIRSF005784 3 191 9.7E-84 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 1 191 6.3E-87 T 28-03-2018 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 Gene3D G3DSA:3.30.70.20 148 180 1.1E-5 T 28-03-2018 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 SUPERFAMILY SSF54862 38 175 2.02E-28 T 28-03-2018 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 4 185 42.751 T 28-03-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 Pfam PF14697 4Fe-4S dicluster domain 110 163 2.3E-16 T 28-03-2018 WM46_RS07440 9e7066d1272ee5bd94dc2f8e4a7602d2 192 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 SMART SM00072 3 187 2.6E-86 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 SUPERFAMILY SSF52540 3 189 7.9E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 Hamap MF_00328 Guanylate kinase [gmk]. 2 187 38.314 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 Gene3D G3DSA:3.30.63.10 52 81 3.6E-27 T 28-03-2018 WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 Pfam PF00625 Guanylate kinase 5 186 1.3E-68 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 Gene3D G3DSA:3.40.50.300 3 51 3.1E-4 T 28-03-2018 WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 4 184 7.2E-76 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 WM46_RS20090 cd56b180a954ff8eae14c403ca84e667 207 Gene3D G3DSA:3.40.50.300 82 188 6.1E-37 T 28-03-2018 WM46_RS24715 adf227a0902f38e54eebc20451dad3bd 177 Pfam PF00419 Fimbrial protein 29 177 3.0E-11 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24715 adf227a0902f38e54eebc20451dad3bd 177 Gene3D G3DSA:2.60.40.1090 26 177 2.5E-25 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24715 adf227a0902f38e54eebc20451dad3bd 177 SUPERFAMILY SSF49401 27 177 1.49E-21 T 28-03-2018 IPR008966 Adhesion domain WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 SUPERFAMILY SSF48179 204 367 7.14E-45 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 SUPERFAMILY SSF51735 1 203 1.43E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 123 8.8E-27 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 149 368 2.5E-69 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 PRINTS PR00084 Mannitol dehydrogenase signature 170 185 9.7E-18 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 9.7E-18 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 9.7E-18 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 PRINTS PR00084 Mannitol dehydrogenase signature 150 163 9.7E-18 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 Gene3D G3DSA:1.10.1040.10 207 381 2.5E-47 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 Gene3D G3DSA:3.40.50.720 1 75 1.1E-6 T 28-03-2018 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 Gene3D G3DSA:3.40.50.720 76 197 1.7E-27 T 28-03-2018 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 41.684 T 28-03-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS20330 a7da23ecdd4aeda52f684cf0009bd45e 381 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 150 162 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 Pfam PF07729 FCD domain 99 226 2.5E-17 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.5E-25 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 Gene3D G3DSA:1.10.10.10 2 76 5.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 SUPERFAMILY SSF48008 95 234 6.8E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 SMART SM00895 99 227 3.0E-16 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 SUPERFAMILY SSF46785 6 76 4.28E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 SMART SM00345 15 74 3.0E-29 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS14265 f98ae1346493105514ccaa84a118e9b9 254 Gene3D G3DSA:1.20.120.530 79 245 3.7E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS19120 f65cadafcfde1e28c46b9fc51f386e0a 67 Pfam PF13627 Prokaryotic lipoprotein-attachment site 8 29 2.9E-9 T 28-03-2018 IPR032831 Prokaryotic lipoprotein-attachment site WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 SMART SM00283 279 526 7.1E-43 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 SUPERFAMILY SSF47170 39 185 4.45E-32 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 338 491 5.6E-36 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 Gene3D G3DSA:1.10.287.950 310 529 9.9E-41 T 28-03-2018 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 SMART SM00304 224 278 2.1E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 404 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 19 44 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 74 89 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 454 483 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 199 219 8.0E-36 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 SUPERFAMILY SSF58104 244 527 9.16E-51 T 28-03-2018 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 Pfam PF02203 Tar ligand binding domain homologue 19 181 1.4E-32 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 Gene3D G3DSA:1.20.120.30 52 184 7.0E-23 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain WM46_RS07050 3e8f1d904005e6724aa5e87054e09cb3 529 Gene3D G3DSA:1.10.287.1060 241 309 0.66 T 28-03-2018 WM46_RS08230 798c7b5db3f3d7e8a850bac3d8a5e789 209 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 89 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM46_RS08230 798c7b5db3f3d7e8a850bac3d8a5e789 209 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 89 2.0E-9 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 WM46_RS20200 ccc35718b3dc36aa4915394b9e4cc1b5 338 Pfam PF01501 Glycosyl transferase family 8 27 276 7.7E-63 T 28-03-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 WM46_RS20200 ccc35718b3dc36aa4915394b9e4cc1b5 338 Pfam PF08437 Glycosyl transferase family 8 C-terminal 278 334 2.4E-19 T 28-03-2018 IPR013645 Glycosyl transferase, family 8, C-terminal GO:0008918|GO:0009103 WM46_RS20200 ccc35718b3dc36aa4915394b9e4cc1b5 338 Gene3D G3DSA:3.90.550.10 26 309 1.0E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS20200 ccc35718b3dc36aa4915394b9e4cc1b5 338 SUPERFAMILY SSF53448 27 295 2.67E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 Pfam PF01134 Glucose inhibited division protein A 8 398 3.1E-170 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 Pfam PF13932 GidA associated domain 403 616 1.8E-77 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 SMART SM01228 546 617 3.2E-44 T 28-03-2018 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 Gene3D G3DSA:3.50.50.60 5 264 2.1E-75 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 SUPERFAMILY SSF51905 97 261 9.23E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 SUPERFAMILY SSF51905 7 66 9.23E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 Gene3D G3DSA:1.10.10.10 538 629 0.011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 2.3E-304 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 WM46_RS19480 811b191f98d27db4b8f0a3fd4e3ba788 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 42.834 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 WM46_RS15070 628e79096bcce178c701946485f2bcce 138 SMART SM00732 3 103 9.9E-41 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 WM46_RS15070 628e79096bcce178c701946485f2bcce 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 3 138 25.924 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 WM46_RS15070 628e79096bcce178c701946485f2bcce 138 Pfam PF03652 Holliday junction resolvase 4 135 4.5E-43 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 WM46_RS15070 628e79096bcce178c701946485f2bcce 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 6 135 6.5E-62 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 WM46_RS15070 628e79096bcce178c701946485f2bcce 138 Gene3D G3DSA:3.30.420.140 1 138 4.7E-43 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 WM46_RS15070 628e79096bcce178c701946485f2bcce 138 SUPERFAMILY SSF53098 3 136 9.1E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13040 ead30728f534b64fd5b729c7676bc592 385 Gene3D G3DSA:3.40.710.10 28 375 3.8E-70 T 28-03-2018 WM46_RS13040 ead30728f534b64fd5b729c7676bc592 385 SUPERFAMILY SSF56601 33 357 4.11E-67 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS13040 ead30728f534b64fd5b729c7676bc592 385 Pfam PF00144 Beta-lactamase 45 357 4.0E-65 T 28-03-2018 IPR001466 Beta-lactamase-related WM46_RS19940 b17a44e5deb0a36e18674a625ffdff2f 161 SUPERFAMILY SSF52728 3 161 6.93E-46 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS19940 b17a44e5deb0a36e18674a625ffdff2f 161 Pfam PF03830 PTS system sorbose subfamily IIB component 4 150 1.5E-44 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS19940 b17a44e5deb0a36e18674a625ffdff2f 161 Gene3D G3DSA:3.40.35.10 3 159 1.7E-48 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 565 677 1.6E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 Pfam PF01627 Hpt domain 810 869 7.7E-10 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 Gene3D G3DSA:3.30.565.10 479 677 9.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 SMART SM00387 565 678 1.4E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 Hamap MF_00980 Phosphotransferase RcsD [rcsD]. 15 889 24.653 T 28-03-2018 IPR030861 Phosphotransferase RcsD GO:0000160|GO:0005887|GO:0009927 WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 SUPERFAMILY SSF47226 803 888 2.22E-20 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 Gene3D G3DSA:1.20.120.160 774 889 8.2E-15 T 28-03-2018 WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 Pfam PF16359 RcsD-ABL domain 687 788 2.6E-41 T 28-03-2018 IPR032306 Phosphotransferase RcsD, RcsD-ABL domain WM46_RS02080 dde10ae7018aa260e521954af8636de1 889 SUPERFAMILY SSF55874 509 680 6.63E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS17150 e42cc9479214bfbb9a363091562f7cbf 489 SUPERFAMILY SSF50249 39 128 2.62E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS17150 e42cc9479214bfbb9a363091562f7cbf 489 Gene3D G3DSA:2.40.50.140 32 127 5.7E-31 T 28-03-2018 WM46_RS17150 e42cc9479214bfbb9a363091562f7cbf 489 Pfam PF00575 S1 RNA binding domain 38 109 1.5E-6 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS17150 e42cc9479214bfbb9a363091562f7cbf 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 426 1.5E-178 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 WM46_RS17150 e42cc9479214bfbb9a363091562f7cbf 489 SMART SM00316 37 122 1.2E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS17150 e42cc9479214bfbb9a363091562f7cbf 489 Pfam PF10150 Ribonuclease E/G family 124 393 4.2E-101 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 WM46_RS03580 da48f66cda283f36d04b7bba81bb0592 351 Pfam PF11761 Cobalamin biosynthesis central region 140 215 7.7E-8 T 28-03-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 WM46_RS03580 da48f66cda283f36d04b7bba81bb0592 351 Gene3D G3DSA:3.30.420.180 221 351 1.2E-27 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 WM46_RS03580 da48f66cda283f36d04b7bba81bb0592 351 SUPERFAMILY SSF159672 6 238 3.66E-58 T 28-03-2018 WM46_RS03580 da48f66cda283f36d04b7bba81bb0592 351 SUPERFAMILY SSF159664 224 349 2.75E-31 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 WM46_RS03580 da48f66cda283f36d04b7bba81bb0592 351 Pfam PF11760 Cobalamin synthesis G N-terminal 55 134 2.6E-35 T 28-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 WM46_RS03580 da48f66cda283f36d04b7bba81bb0592 351 Pfam PF01890 Cobalamin synthesis G C-terminus 231 346 1.1E-23 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 WM46_RS11900 5721c830a9112ffe5fe0f06b376fd595 159 Pfam PF07883 Cupin domain 68 128 9.6E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS11900 5721c830a9112ffe5fe0f06b376fd595 159 SUPERFAMILY SSF51182 35 157 1.02E-31 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS11900 5721c830a9112ffe5fe0f06b376fd595 159 Gene3D G3DSA:2.60.120.10 22 159 6.5E-30 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS11975 8777bbbc18866b6b099fc1376342e293 83 Pfam PF07338 Protein of unknown function (DUF1471) 32 83 3.8E-18 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS11975 8777bbbc18866b6b099fc1376342e293 83 SUPERFAMILY SSF159871 3 83 1.22E-21 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS11975 8777bbbc18866b6b099fc1376342e293 83 Gene3D G3DSA:3.30.1660.10 20 83 2.0E-20 T 28-03-2018 IPR025543 Dodecin-like WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 Pfam PF12698 ABC-2 family transporter protein 569 903 1.9E-36 T 28-03-2018 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 SUPERFAMILY SSF52540 267 499 1.94E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 Gene3D G3DSA:3.40.50.300 9 268 1.1E-56 T 28-03-2018 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 Gene3D G3DSA:3.40.50.300 273 560 2.6E-65 T 28-03-2018 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 SMART SM00382 301 486 1.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 SMART SM00382 37 225 0.039 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 Gene3D G3DSA:3.40.1710.10 578 731 1.4E-22 T 28-03-2018 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 Pfam PF00005 ABC transporter 293 436 5.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 Pfam PF00005 ABC transporter 28 175 2.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS20825 986d8e842168f9b7dd53bd55f9a9b0eb 912 SUPERFAMILY SSF52540 14 238 3.28E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 687 6.1E-247 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 Gene3D G3DSA:3.40.50.300 2 626 1.4E-36 T 28-03-2018 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 Pfam PF02421 Ferrous iron transport protein B 5 162 3.8E-65 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 Pfam PF07670 Nucleoside recognition 512 689 2.1E-36 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 Pfam PF07670 Nucleoside recognition 353 443 6.2E-13 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 Pfam PF07664 Ferrous iron transport protein B C terminus 455 507 1.0E-21 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 157 1.2E-11 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS17880 d46447818e03b9ee50e6f697a89c8aa5 773 SUPERFAMILY SSF52540 4 171 8.33E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 Hamap MF_00246 Galactokinase [galK]. 25 381 45.136 T 28-03-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 TIGRFAM TIGR00131 gal_kin: galactokinase 5 382 1.1E-168 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 Gene3D G3DSA:3.30.230.10 2 206 1.9E-58 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 Pfam PF10509 Galactokinase galactose-binding signature 10 57 1.3E-21 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 SUPERFAMILY SSF55060 205 380 4.48E-52 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PIRSF PIRSF000530 1 382 1.2E-124 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 Gene3D G3DSA:3.30.70.890 207 381 2.4E-57 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 Pfam PF00288 GHMP kinases N terminal domain 114 181 4.6E-14 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00959 Mevalonate kinase family signature 25 49 5.8E-46 T 28-03-2018 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00959 Mevalonate kinase family signature 119 141 5.8E-46 T 28-03-2018 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00959 Mevalonate kinase family signature 328 345 5.8E-46 T 28-03-2018 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00959 Mevalonate kinase family signature 162 181 5.8E-46 T 28-03-2018 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 SUPERFAMILY SSF54211 3 203 1.44E-63 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00473 Galactokinase signature 27 45 4.9E-30 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00473 Galactokinase signature 92 103 4.9E-30 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00473 Galactokinase signature 112 130 4.9E-30 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 PRINTS PR00473 Galactokinase signature 263 277 4.9E-30 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 WM46_RS10710 e28c07d22233388d54989cace3d51de6 382 Pfam PF08544 GHMP kinases C terminal 279 361 8.4E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 Pfam PF03476 MOSC N-terminal beta barrel domain 2 116 8.9E-29 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 Gene3D G3DSA:3.10.20.30 272 368 6.9E-16 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 Gene3D G3DSA:2.40.33.20 1 271 8.1E-50 T 28-03-2018 WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 SUPERFAMILY SSF50800 147 264 9.42E-17 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 SUPERFAMILY SSF50800 4 50 9.42E-17 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 292 362 3.1E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 Pfam PF03473 MOSC domain 139 262 6.4E-29 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 SUPERFAMILY SSF54292 285 367 3.01E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS09695 6b2c4e1d1e89ecd0750ae0af9afc33f2 369 SUPERFAMILY SSF141673 4 132 4.45E-28 T 28-03-2018 WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 38 769 2.3E-264 T 28-03-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 Gene3D G3DSA:1.10.3810.10 42 243 1.2E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 Pfam PF00912 Transglycosylase 62 226 2.0E-50 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 Gene3D G3DSA:3.40.710.10 254 605 6.9E-63 T 28-03-2018 WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 Pfam PF00905 Penicillin binding protein transpeptidase domain 313 424 8.1E-8 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 685 767 4.0E-15 T 28-03-2018 IPR009647 Penicillin-binding, C-terminal WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 SUPERFAMILY SSF56601 208 636 3.52E-91 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS00680 4e9e1703ed67262897c4ba57ac5af36b 770 SUPERFAMILY SSF53955 39 258 1.66E-65 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS26105 335f44c25378046f4ebf379f9ebe494d 184 Pfam PF13523 Acetyltransferase (GNAT) domain 15 161 8.4E-40 T 28-03-2018 WM46_RS26105 335f44c25378046f4ebf379f9ebe494d 184 TIGRFAM TIGR04431 N6_acetyl_AAC6: aminoglycoside N(6')-acetyltransferase, AacA4 family 2 184 4.3E-117 T 28-03-2018 IPR030971 Aminoglycoside N(6')-acetyltransferase, AacA4 type WM46_RS26105 335f44c25378046f4ebf379f9ebe494d 184 Gene3D G3DSA:3.40.630.30 1 184 5.6E-32 T 28-03-2018 WM46_RS26105 335f44c25378046f4ebf379f9ebe494d 184 SUPERFAMILY SSF55729 5 175 1.42E-46 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS10900 53ee9dc1e0a0682da6c9e6a14c27d9ba 333 Gene3D G3DSA:3.40.710.10 23 332 4.0E-112 T 28-03-2018 WM46_RS10900 53ee9dc1e0a0682da6c9e6a14c27d9ba 333 Pfam PF04960 Glutaminase 46 330 2.8E-105 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 WM46_RS10900 53ee9dc1e0a0682da6c9e6a14c27d9ba 333 Hamap MF_00313 Glutaminase [glsA]. 28 330 40.447 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 WM46_RS10900 53ee9dc1e0a0682da6c9e6a14c27d9ba 333 SUPERFAMILY SSF56601 28 330 1.43E-104 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS10900 53ee9dc1e0a0682da6c9e6a14c27d9ba 333 TIGRFAM TIGR03814 Gln_ase: glutaminase A 37 330 3.4E-106 T 28-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 WM46_RS08000 0a2f1448409e79ca0991118d5d3a16b3 326 SUPERFAMILY SSF81345 6 323 1.57E-84 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS08000 0a2f1448409e79ca0991118d5d3a16b3 326 Pfam PF01032 FecCD transport family 22 323 5.3E-87 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS08000 0a2f1448409e79ca0991118d5d3a16b3 326 Gene3D G3DSA:1.10.3470.10 1 326 7.3E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS08000 0a2f1448409e79ca0991118d5d3a16b3 326 Hamap MF_01004 Vitamin B12 import system permease protein BtuC [btuC]. 1 326 32.183 T 28-03-2018 IPR023691 ABC transporter, vitamin B12 import, permease protein BtuC GO:0015889|GO:0016020 WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 258 416 1.2E-34 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Gene3D G3DSA:3.20.20.450 424 690 1.5E-91 T 28-03-2018 IPR001633 EAL domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 SMART SM00267 249 420 1.3E-52 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Gene3D G3DSA:3.30.70.270 253 423 1.7E-53 T 28-03-2018 WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Pfam PF03707 Bacterial signalling protein N terminal repeat 184 241 1.7E-6 T 28-03-2018 IPR005330 MHYT domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Pfam PF03707 Bacterial signalling protein N terminal repeat 118 172 4.4E-11 T 28-03-2018 IPR005330 MHYT domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Pfam PF03707 Bacterial signalling protein N terminal repeat 52 99 5.2E-15 T 28-03-2018 IPR005330 MHYT domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 SUPERFAMILY SSF141868 436 685 1.44E-85 T 28-03-2018 IPR001633 EAL domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Pfam PF00563 EAL domain 438 671 1.4E-71 T 28-03-2018 IPR001633 EAL domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 Pfam PF00990 Diguanylate cyclase, GGDEF domain 261 415 1.0E-42 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 SMART SM00052 430 676 1.4E-103 T 28-03-2018 IPR001633 EAL domain WM46_RS06215 d1bb0bf3132f6ea408eebd0a394fc159 704 SUPERFAMILY SSF55073 265 422 1.02E-45 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 Gene3D G3DSA:3.40.50.720 1 245 8.7E-65 T 28-03-2018 WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 189 3.1E-7 T 28-03-2018 WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 SUPERFAMILY SSF51735 4 244 5.19E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS22135 001e99d0b6db6161b4cf7e993248e94a 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 5.6E-53 T 28-03-2018 WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 Pfam PF00455 DeoR C terminal sensor domain 79 236 9.3E-47 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 SMART SM00420 8 61 3.7E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 SUPERFAMILY SSF100950 78 238 7.85E-26 T 28-03-2018 WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 Gene3D G3DSA:1.10.10.10 1 58 2.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 Pfam PF08220 DeoR-like helix-turn-helix domain 8 64 1.3E-20 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 Gene3D G3DSA:3.40.50.1360 77 243 1.3E-30 T 28-03-2018 WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 42 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS06440 9f23481cb2976f8ea45d13fe2a6c7697 258 SMART SM01134 77 237 1.9E-58 T 28-03-2018 WM46_RS08140 9b09f9b1ceed27445cd3be670de3353c 452 Pfam PF02378 Phosphotransferase system, EIIC 30 363 3.0E-46 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS08140 9b09f9b1ceed27445cd3be670de3353c 452 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 440 1.3E-173 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 WM46_RS08140 9b09f9b1ceed27445cd3be670de3353c 452 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 440 1.3E-173 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS08140 9b09f9b1ceed27445cd3be670de3353c 452 PIRSF PIRSF006351 1 448 1.7E-133 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 Gene3D G3DSA:3.30.1390.10 51 121 7.5E-31 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 8.0E-28 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 Gene3D G3DSA:1.20.5.710 2 50 1.1E-17 T 28-03-2018 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 SUPERFAMILY SSF54736 50 121 3.84E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 49 1.1E-15 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 3.8E-31 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 SUPERFAMILY SSF48300 3 57 3.53E-16 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 2.4E-48 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21185 abd935bea3fa5a127881c846f54dd2fa 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 25.484 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 Pfam PF01514 Secretory protein of YscJ/FliF family 33 221 6.4E-76 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 Gene3D G3DSA:3.30.70.1530 53 116 4.9E-9 T 28-03-2018 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 Pfam PF08345 Flagellar M-ring protein C-terminal 253 441 2.1E-51 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 PIRSF PIRSF004862 2 564 1.2E-178 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 PRINTS PR01009 Flagellar M-ring protein signature 122 140 1.2E-45 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 PRINTS PR01009 Flagellar M-ring protein signature 154 168 1.2E-45 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 PRINTS PR01009 Flagellar M-ring protein signature 197 215 1.2E-45 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 PRINTS PR01009 Flagellar M-ring protein signature 369 393 1.2E-45 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 PRINTS PR01009 Flagellar M-ring protein signature 266 284 1.2E-45 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS03835 5b2616af6c056c12cec5ffc23803dfe0 564 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 8 563 4.0E-216 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SUPERFAMILY SSF81901 85 216 1.05E-18 T 28-03-2018 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Gene3D G3DSA:2.60.40.1180 24 47 0.22 T 28-03-2018 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Gene3D G3DSA:2.60.40.1180 78 176 1.4E-10 T 28-03-2018 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Gene3D G3DSA:2.60.40.1180 49 77 0.0017 T 28-03-2018 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Gene3D G3DSA:2.60.40.1180 177 222 0.01 T 28-03-2018 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Pfam PF08238 Sel1 repeat 85 101 25.0 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Pfam PF08238 Sel1 repeat 180 215 1.4E-4 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Pfam PF08238 Sel1 repeat 41 66 0.088 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 Pfam PF08238 Sel1 repeat 143 173 6.5E-4 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SUPERFAMILY SSF81901 25 103 7.06E-11 T 28-03-2018 WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SMART SM00671 67 101 24.0 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SMART SM00671 179 216 0.0018 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SMART SM00671 35 66 4.5 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SMART SM00671 142 177 7.8E-5 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS21815 20b8be83509d37f09aaafce8f68df241 229 SMART SM00671 102 137 140.0 T 28-03-2018 IPR006597 Sel1-like repeat WM46_RS24230 72e98ccce2cbf6d1999d3ea57b2b82a7 103 Hamap MF_00684 UPF0267 protein YqfB [yqfB]. 2 103 31.659 T 28-03-2018 IPR008314 Uncharacterised conserved protein UCP029143 WM46_RS24230 72e98ccce2cbf6d1999d3ea57b2b82a7 103 Pfam PF04266 ASCH domain 6 94 1.7E-15 T 28-03-2018 IPR007374 ASCH domain WM46_RS24230 72e98ccce2cbf6d1999d3ea57b2b82a7 103 SUPERFAMILY SSF88697 1 102 1.06E-32 T 28-03-2018 IPR015947 PUA-like domain WM46_RS24230 72e98ccce2cbf6d1999d3ea57b2b82a7 103 PIRSF PIRSF029143 1 103 4.3E-51 T 28-03-2018 IPR008314 Uncharacterised conserved protein UCP029143 WM46_RS24230 72e98ccce2cbf6d1999d3ea57b2b82a7 103 SMART SM01022 6 102 1.6E-25 T 28-03-2018 IPR007374 ASCH domain WM46_RS24230 72e98ccce2cbf6d1999d3ea57b2b82a7 103 Gene3D G3DSA:2.30.130.30 1 103 1.7E-20 T 28-03-2018 WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 SMART SM00244 95 255 3.0E-43 T 28-03-2018 IPR001107 Band 7 domain WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 SUPERFAMILY SSF117892 128 259 1.27E-20 T 28-03-2018 IPR001107 Band 7 domain WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 Pfam PF12221 Bacterial membrane protein N terminal 1 59 3.5E-15 T 28-03-2018 IPR020980 Menbrane protein HflK, N-terminal WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 TIGRFAM TIGR01933 hflK: HflK protein 97 356 1.8E-125 T 28-03-2018 IPR010201 HflK GO:0016021 WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 PRINTS PR00721 Stomatin signature 184 201 1.2E-6 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 PRINTS PR00721 Stomatin signature 102 124 1.2E-6 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 PRINTS PR00721 Stomatin signature 149 170 1.2E-6 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS22895 4e7b3471e16fed483d1d841903d34b12 418 Pfam PF01145 SPFH domain / Band 7 family 99 270 5.2E-31 T 28-03-2018 IPR001107 Band 7 domain WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Pfam PF00512 His Kinase A (phospho-acceptor) domain 469 533 5.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Gene3D G3DSA:3.30.565.10 529 692 2.1E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SUPERFAMILY SSF52172 701 815 3.48E-40 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Gene3D G3DSA:1.10.287.130 473 528 5.8E-19 T 28-03-2018 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Gene3D G3DSA:3.40.50.2300 809 948 3.2E-40 T 28-03-2018 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 645 4.8E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 689 4.8E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 631 4.8E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 670 4.8E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SUPERFAMILY SSF47384 453 535 2.16E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SUPERFAMILY SSF55874 523 692 3.01E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SMART SM00388 469 534 1.7E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Gene3D G3DSA:3.30.450.20 331 472 6.8E-7 T 28-03-2018 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SUPERFAMILY SSF52172 824 946 3.98E-38 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SMART SM00448 825 936 1.7E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Hamap MF_00979 Sensor histidine kinase RcsC [rcsC]. 24 941 27.083 T 28-03-2018 IPR030856 Sensor histidine kinase RcsC GO:0000155|GO:0000160|GO:0016021|GO:0042710 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 SMART SM00387 581 692 2.9E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 581 690 1.3E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Pfam PF09456 RcsC Alpha-Beta-Loop (ABL) 709 799 9.1E-34 T 28-03-2018 IPR019017 Signal transduction histidine kinase RcsC, alpha-beta loop, C-terminal GO:0000160|GO:0004673|GO:0004871|GO:0005524|GO:0005886|GO:0006355|GO:0016021|GO:0018106 WM46_RS02070 fb48a063bbf61fd416f66d84305c9799 948 Pfam PF00072 Response regulator receiver domain 827 936 4.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 Pfam PF00384 Molybdopterin oxidoreductase 107 162 1.3E-6 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 SUPERFAMILY SSF53706 35 195 3.53E-57 T 28-03-2018 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 Gene3D G3DSA:2.20.25.90 37 108 7.6E-21 T 28-03-2018 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 Gene3D G3DSA:3.40.50.740 109 195 5.7E-13 T 28-03-2018 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 SMART SM00926 43 104 4.9E-22 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS18680 863eb294c1741676fbb63022081dd4bc 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 103 4.0E-19 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS24080 ac9c79a42ffad26f590901d56fea7cea 260 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 129 139 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 WM46_RS24080 ac9c79a42ffad26f590901d56fea7cea 260 Gene3D G3DSA:3.20.20.140 3 260 2.9E-74 T 28-03-2018 WM46_RS24080 ac9c79a42ffad26f590901d56fea7cea 260 PIRSF PIRSF005902 1 260 1.6E-71 T 28-03-2018 IPR001130 TatD family GO:0016788 WM46_RS24080 ac9c79a42ffad26f590901d56fea7cea 260 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 5 13 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 WM46_RS24080 ac9c79a42ffad26f590901d56fea7cea 260 SUPERFAMILY SSF51556 5 258 3.13E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS24080 ac9c79a42ffad26f590901d56fea7cea 260 Pfam PF01026 TatD related DNase 6 256 6.7E-67 T 28-03-2018 IPR001130 TatD family GO:0016788 WM46_RS12840 e74c577c514e48d9a59a20dedceddce7 147 SUPERFAMILY SSF55804 4 144 5.1E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS12840 e74c577c514e48d9a59a20dedceddce7 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 144 5.2E-24 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS12840 e74c577c514e48d9a59a20dedceddce7 147 Gene3D G3DSA:3.40.930.10 2 146 2.2E-23 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 SUPERFAMILY SSF52518 356 540 3.13E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 SUPERFAMILY SSF52518 5 179 1.54E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 Gene3D G3DSA:3.40.50.970 1 198 3.4E-43 T 28-03-2018 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 Gene3D G3DSA:3.40.50.970 358 543 8.8E-35 T 28-03-2018 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 SUPERFAMILY SSF52467 167 334 2.88E-24 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 177 6.2E-31 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 PIRSF PIRSF036565 1 551 1.1E-197 T 28-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 527 2.9E-18 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 Gene3D G3DSA:3.40.50.1220 200 357 2.1E-21 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 202 317 5.4E-14 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 WM46_RS01305 0fb9d5c11832a3b07aeed9d2862356e1 551 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 SUPERFAMILY SSF47144 77 170 3.79E-26 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 SMART SM00271 1 66 6.0E-8 T 28-03-2018 IPR001623 DnaJ domain WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 169 24.888 T 28-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 Gene3D G3DSA:1.10.287.110 1 79 1.4E-9 T 28-03-2018 IPR001623 DnaJ domain WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 Pfam PF07743 HSCB C-terminal oligomerisation domain 88 160 7.7E-18 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 13 168 4.7E-66 T 28-03-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 Gene3D G3DSA:1.20.1280.20 81 170 7.3E-25 T 28-03-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS00635 ff2aa6d67870fce29b168ce267a0ec27 171 SUPERFAMILY SSF46565 1 75 2.88E-17 T 28-03-2018 IPR001623 DnaJ domain WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 Gene3D G3DSA:1.10.10.10 1 61 5.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 SMART SM01134 72 233 3.1E-71 T 28-03-2018 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 Gene3D G3DSA:3.40.50.1360 64 241 1.2E-39 T 28-03-2018 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.6E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.6E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 Pfam PF00455 DeoR C terminal sensor domain 74 231 1.1E-54 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 SUPERFAMILY SSF46785 3 76 2.67E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 SUPERFAMILY SSF100950 73 234 5.44E-30 T 28-03-2018 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 SMART SM00420 6 58 7.9E-27 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS17965 630a3da988cdcfde9b782935a991d0db 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.2E-24 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 SUPERFAMILY SSF52540 1 347 1.38E-128 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 SUPERFAMILY SSF52540 363 812 8.29E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 PIRSF PIRSF000980 1 1122 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 Gene3D G3DSA:1.10.10.160 86 185 7.7E-32 T 28-03-2018 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 806 0.0 T 28-03-2018 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 Gene3D G3DSA:3.40.50.300 327 811 1.1E-71 T 28-03-2018 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1087 0.0 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 SUPERFAMILY SSF52980 820 1120 4.83E-97 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS24900 f684c4c976627f33f98f44bde97d2c37 1122 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1122 21.172 T 28-03-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 WM46_RS26115 ad03c72905ebd8dfdc9442bc516593f0 274 ProSitePatterns PS00337 Beta-lactamase class-D active site. 56 66 - T 28-03-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 WM46_RS26115 ad03c72905ebd8dfdc9442bc516593f0 274 Gene3D G3DSA:3.40.710.10 20 264 8.5E-18 T 28-03-2018 WM46_RS26115 ad03c72905ebd8dfdc9442bc516593f0 274 SUPERFAMILY SSF56601 33 260 4.47E-28 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS26115 ad03c72905ebd8dfdc9442bc516593f0 274 Pfam PF00905 Penicillin binding protein transpeptidase domain 42 244 3.8E-29 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS10840 a7de18fa61bf175e65f6303de1968f7d 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 379 2.2E-204 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM46_RS10840 a7de18fa61bf175e65f6303de1968f7d 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 362 1.1E-110 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM46_RS10840 a7de18fa61bf175e65f6303de1968f7d 379 PIRSF PIRSF000267 2 378 5.2E-134 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM46_RS16315 3917721cdb119dce31c6f1b2bc2dc78c 168 Pfam PF03167 Uracil DNA glycosylase superfamily 6 159 1.1E-22 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS16315 3917721cdb119dce31c6f1b2bc2dc78c 168 SUPERFAMILY SSF52141 2 163 1.26E-45 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS16315 3917721cdb119dce31c6f1b2bc2dc78c 168 Gene3D G3DSA:3.40.470.10 4 165 3.6E-48 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 WM46_RS16315 3917721cdb119dce31c6f1b2bc2dc78c 168 Hamap MF_01956 G/U mismatch-specific DNA glycosylase [mug]. 1 168 48.098 T 28-03-2018 IPR023502 G/U mismatch-specific DNA glycosylase, bacterial GO:0006281|GO:0019104 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Gene3D G3DSA:1.10.601.10 91 501 9.0E-55 T 28-03-2018 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 624 650 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Gene3D G3DSA:1.10.10.10 502 552 3.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Gene3D G3DSA:1.25.40.20 13 90 4.9E-16 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 SUPERFAMILY SSF88659 588 660 3.18E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 SUPERFAMILY SSF88946 290 344 8.9E-42 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 SUPERFAMILY SSF88946 396 501 8.9E-42 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 457 470 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 428 652 9.5E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 SMART SM00248 43 72 9.8E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Pfam PF04545 Sigma-70, region 4 599 652 8.9E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Gene3D G3DSA:1.10.10.10 593 664 3.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 PRINTS PR00046 Major sigma-70 factor signature 481 489 1.9E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 PRINTS PR00046 Major sigma-70 factor signature 457 470 1.9E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 PRINTS PR00046 Major sigma-70 factor signature 603 615 1.9E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 PRINTS PR00046 Major sigma-70 factor signature 624 639 1.9E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 PRINTS PR00046 Major sigma-70 factor signature 639 650 1.9E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Pfam PF13606 Ankyrin repeat 44 71 1.2E-5 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 Pfam PF04542 Sigma-70 region 2 433 500 1.3E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS25795 023ac553cd92ff00124051a01bfd8f99 678 SUPERFAMILY SSF48403 14 88 2.8E-14 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain WM46_RS06910 5abbd3e73d4d1b1dc0fb0725248781da 442 Gene3D G3DSA:3.20.20.80 73 422 4.5E-45 T 28-03-2018 WM46_RS06910 5abbd3e73d4d1b1dc0fb0725248781da 442 SUPERFAMILY SSF51445 85 391 6.09E-32 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS06910 5abbd3e73d4d1b1dc0fb0725248781da 442 Pfam PF02638 Glycosyl hydrolase-like 10 59 392 1.2E-119 T 28-03-2018 IPR003790 Glycosyl hydrolase-like 10 WM46_RS13665 83ac2253d1a9b3ec0113b3c88b70d4c6 414 Gene3D G3DSA:1.20.1440.110 49 153 3.5E-24 T 28-03-2018 WM46_RS13665 83ac2253d1a9b3ec0113b3c88b70d4c6 414 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 1 414 1.1E-213 T 28-03-2018 IPR010520 UPF0255 family WM46_RS13665 83ac2253d1a9b3ec0113b3c88b70d4c6 414 Gene3D G3DSA:3.40.50.1820 154 414 4.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS13665 83ac2253d1a9b3ec0113b3c88b70d4c6 414 Hamap MF_01063 Esterase FrsA [frsA]. 1 414 60.843 T 28-03-2018 IPR010520 UPF0255 family WM46_RS13665 83ac2253d1a9b3ec0113b3c88b70d4c6 414 SUPERFAMILY SSF53474 46 413 1.87E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS22025 5f9a53a86c59419653a7e3fc3c6cd696 257 Gene3D G3DSA:1.20.1630.10 1 251 1.2E-30 T 28-03-2018 WM46_RS22025 5f9a53a86c59419653a7e3fc3c6cd696 257 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 250 5.2E-33 T 28-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 WM46_RS09670 5cabc49523b1b177c585f68ca5fc3293 187 SUPERFAMILY SSF159594 24 183 3.4E-29 T 28-03-2018 WM46_RS09670 5cabc49523b1b177c585f68ca5fc3293 187 Gene3D G3DSA:3.40.50.10610 12 187 4.3E-43 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component WM46_RS09670 5cabc49523b1b177c585f68ca5fc3293 187 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 26 180 1.3E-40 T 28-03-2018 IPR005586 ABC-type transport auxiliary lipoprotein component WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 SUPERFAMILY SSF161098 11 265 7.06E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 SUPERFAMILY SSF161098 286 525 1.42E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 376 523 6.7E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 267 7.5E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 Gene3D G3DSA:1.10.3720.10 322 532 3.3E-26 T 28-03-2018 WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 TIGRFAM TIGR01253 thiP: thiamine/thiamine pyrophosphate ABC transporter, permease protein 8 525 4.6E-280 T 28-03-2018 IPR005947 Thiamine ABC transporter, permease protein GO:0005215|GO:0015888|GO:0016021 WM46_RS14495 a87888a8b1c01a579ab1e917f53ed8ef 536 Gene3D G3DSA:1.10.3720.10 8 273 2.0E-30 T 28-03-2018 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 Hamap MF_00513 HTH-type transcriptional regulator ArgP [argP]. 1 296 58.615 T 28-03-2018 IPR023490 HTH-type transcriptional regulator ArgP, Gammaproteobacteria WM46_RS24145 b700246edd35542153c685d5de59cf78 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.1E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 Pfam PF03466 LysR substrate binding domain 93 288 4.5E-12 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24145 b700246edd35542153c685d5de59cf78 297 Gene3D G3DSA:3.40.190.10 179 262 1.5E-8 T 28-03-2018 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 SUPERFAMILY SSF46785 4 110 6.66E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24145 b700246edd35542153c685d5de59cf78 297 Gene3D G3DSA:1.10.10.10 2 82 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24145 b700246edd35542153c685d5de59cf78 297 Gene3D G3DSA:3.40.190.10 92 178 1.7E-34 T 28-03-2018 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 SUPERFAMILY SSF53850 92 289 7.6E-19 T 28-03-2018 WM46_RS24145 b700246edd35542153c685d5de59cf78 297 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 5 293 2.1E-112 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 SMART SM00419 201 249 2.8E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 207 223 2.4E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 223 238 2.4E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 Gene3D G3DSA:2.60.120.10 38 179 2.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 SUPERFAMILY SSF46785 179 259 2.19E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 SUPERFAMILY SSF51206 37 176 1.44E-31 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 SMART SM00100 44 165 2.9E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 Pfam PF13545 Crp-like helix-turn-helix domain 182 254 8.1E-16 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 Pfam PF00027 Cyclic nucleotide-binding domain 65 146 1.1E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 ProSitePatterns PS00042 Crp-type HTH domain signature. 209 232 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 WM46_RS06160 2b5dd05080723300fc7531ea596d742c 264 Gene3D G3DSA:1.10.10.10 180 264 1.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 SUPERFAMILY SSF54680 337 439 3.27E-32 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 SUPERFAMILY SSF52418 74 334 1.57E-88 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Pfam PF00591 Glycosyl transferase family, a/b domain 79 309 5.7E-53 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 113 128 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Gene3D G3DSA:1.20.970.10 3 67 1.6E-21 T 28-03-2018 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Gene3D G3DSA:3.90.1170.30 343 429 6.6E-29 T 28-03-2018 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Hamap MF_01628 Thymidine phosphorylase [deoA]. 2 438 47.075 T 28-03-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 SMART SM00941 350 424 1.2E-29 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 2 438 4.4E-235 T 28-03-2018 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 67 2.5E-19 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 5 423 1.3E-168 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 PIRSF PIRSF000478 1 439 3.2E-152 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 350 422 8.8E-25 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 Gene3D G3DSA:3.40.1030.10 69 342 2.9E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24100 69d7761c82e95caa70a492b788cd7d6a 440 SUPERFAMILY SSF47648 3 70 8.9E-22 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 SUPERFAMILY SSF90123 166 460 3.79E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 SUPERFAMILY SSF52540 475 695 1.45E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 Pfam PF00005 ABC transporter 497 646 3.2E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 Gene3D G3DSA:3.90.70.10 9 140 3.9E-27 T 28-03-2018 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 Gene3D G3DSA:3.40.50.300 477 698 7.9E-49 T 28-03-2018 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 ProSitePatterns PS00211 ABC transporters family signature. 618 632 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 Pfam PF03412 Peptidase C39 family 8 134 7.4E-25 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 Gene3D G3DSA:1.20.1560.10 161 449 1.1E-18 T 28-03-2018 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 Pfam PF00664 ABC transporter transmembrane region 170 431 6.3E-9 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS22100 95abf3726dbec6f447e4e2a3063df589 702 SMART SM00382 506 694 1.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 Pfam PF00271 Helicase conserved C-terminal domain 241 343 8.2E-14 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 Pfam PF04851 Type III restriction enzyme, res subunit 3 154 1.4E-24 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 Gene3D G3DSA:3.40.50.300 244 577 7.5E-17 T 28-03-2018 WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 SUPERFAMILY SSF57829 423 466 5.49E-7 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 Gene3D G3DSA:3.40.50.300 1 243 2.7E-31 T 28-03-2018 WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 SMART SM00487 1 185 3.7E-20 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 SMART SM00490 266 345 6.1E-11 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 SUPERFAMILY SSF52540 237 361 1.97E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02250 d6fa2c9b8354bf5bacfedfbeddb96d2f 586 SUPERFAMILY SSF52540 50 169 1.97E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01955 9c108278c36f868a79183d48e6929d55 174 Gene3D G3DSA:1.10.10.60 117 169 5.7E-4 T 28-03-2018 WM46_RS01955 9c108278c36f868a79183d48e6929d55 174 Pfam PF04754 Putative transposase, YhgA-like 7 75 4.5E-18 T 28-03-2018 IPR006842 Transposase (putative), YhgA-like WM46_RS01955 9c108278c36f868a79183d48e6929d55 174 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 6 169 6.8E-21 T 28-03-2018 IPR010106 Recombination-promoting nuclease RpnA WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 SUPERFAMILY SSF55781 95 271 1.57E-48 T 28-03-2018 IPR029016 GAF domain-like WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 Gene3D G3DSA:1.10.10.10 7 85 6.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 Pfam PF01614 Bacterial transcriptional regulator 144 267 9.8E-41 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 SUPERFAMILY SSF46785 24 97 1.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 SMART SM00346 24 114 4.4E-38 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 Pfam PF09339 IclR helix-turn-helix domain 26 76 1.1E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS21355 f3dc5376232a69e2c4751b4ccb95b840 274 Gene3D G3DSA:3.30.450.40 95 274 5.8E-49 T 28-03-2018 IPR029016 GAF domain-like WM46_RS04635 50351b092adb8a13a7f38d5156d7b883 149 Gene3D G3DSA:1.10.530.40 1 149 1.2E-55 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 WM46_RS04635 50351b092adb8a13a7f38d5156d7b883 149 Pfam PF00959 Phage lysozyme 32 141 2.6E-21 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 WM46_RS04635 50351b092adb8a13a7f38d5156d7b883 149 SUPERFAMILY SSF53955 2 149 1.28E-50 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS12155 3b0c5f3c6378ffad4a4a0f26f4802874 205 Pfam PF02498 BRO family, N-terminal domain 38 125 3.4E-8 T 28-03-2018 IPR003497 BRO N-terminal domain WM46_RS12155 3b0c5f3c6378ffad4a4a0f26f4802874 205 SMART SM01040 32 130 2.7E-7 T 28-03-2018 IPR003497 BRO N-terminal domain WM46_RS08845 03d9d1758746f381ac3a1021ee2b8b95 186 Pfam PF07273 Protein of unknown function (DUF1439) 27 178 4.3E-55 T 28-03-2018 IPR010835 Protein of unknown function DUF1439 WM46_RS00230 e7a7273ea4bea15f960a0a81c37fb966 124 Pfam PF10973 Protein of unknown function (DUF2799) 31 114 7.5E-21 T 28-03-2018 IPR021242 Protein of unknown function DUF2799 WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 2 235 7.5E-20 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 28-03-2018 WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 261 7.0E-52 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 ProSitePatterns PS01228 Hypothetical cof family signature 1. 2 13 - T 28-03-2018 WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 Gene3D G3DSA:3.40.50.1000 1 269 1.7E-33 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 SUPERFAMILY SSF56784 2 263 5.79E-58 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21450 773f809f15fb013d02b0ca300b2ec6f5 287 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 2 261 8.2E-47 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS11500 d0ee426efb9e0a30d758cbe999027eab 302 TIGRFAM TIGR03125 citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG 22 292 4.1E-110 T 28-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 WM46_RS11500 d0ee426efb9e0a30d758cbe999027eab 302 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 24 291 3.8E-84 T 28-03-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 WM46_RS11500 d0ee426efb9e0a30d758cbe999027eab 302 Hamap MF_00397 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [citG]. 7 302 183.301 T 28-03-2018 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 Pfam PF01145 SPFH domain / Band 7 family 22 203 8.4E-34 T 28-03-2018 IPR001107 Band 7 domain WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 SUPERFAMILY SSF117892 49 183 2.09E-41 T 28-03-2018 IPR001107 Band 7 domain WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 ProSitePatterns PS01270 Band 7 protein family signature. 132 160 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 PRINTS PR00721 Stomatin signature 108 125 2.5E-27 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 PRINTS PR00721 Stomatin signature 128 151 2.5E-27 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 PRINTS PR00721 Stomatin signature 73 94 2.5E-27 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 PRINTS PR00721 Stomatin signature 171 192 2.5E-27 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 PRINTS PR00721 Stomatin signature 152 170 2.5E-27 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 Pfam PF16200 C-terminal region of band_7 238 297 1.4E-7 T 28-03-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 WM46_RS12290 c848028cf9532e26f426dcc530564dc9 304 SMART SM00244 18 176 4.6E-60 T 28-03-2018 IPR001107 Band 7 domain WM46_RS16160 f751b20b18fc2047278ae78b1b038888 58 Pfam PF13260 Protein of unknown function (DUF4051) 1 53 7.9E-39 T 28-03-2018 IPR025125 Protein of unknown function DUF4051 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 Pfam PF08281 Sigma-70, region 4 112 164 4.8E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 Pfam PF04542 Sigma-70 region 2 16 81 2.1E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 Gene3D G3DSA:1.10.1740.10 2 77 3.6E-14 T 28-03-2018 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 38 68 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 164 3.5E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 SUPERFAMILY SSF88946 13 101 3.18E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 Gene3D G3DSA:1.10.10.10 78 165 9.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13420 f286eb04285b0e8a841da9409d9ba357 173 SUPERFAMILY SSF88659 88 164 4.36E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 167 3.1E-36 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 PIRSF PIRSF006728 1 384 4.4E-110 T 28-03-2018 IPR008135 Competence-induced protein CinA WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 Gene3D G3DSA:3.90.950.20 243 321 0.0056 T 28-03-2018 WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 SMART SM00852 5 172 8.2E-35 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 SUPERFAMILY SSF142433 250 378 2.22E-6 T 28-03-2018 IPR008136 CinA, C-terminal WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 397 7.3E-171 T 28-03-2018 IPR008135 Competence-induced protein CinA WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 Gene3D G3DSA:3.40.980.10 1 172 3.0E-38 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 Pfam PF00994 Probable molybdopterin binding domain 6 170 1.6E-30 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 SUPERFAMILY SSF53218 2 203 8.51E-36 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS01930 4fc14e4b5088449dca5a555d5ef42d64 398 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 398 117.034 T 28-03-2018 IPR008135 Competence-induced protein CinA WM46_RS20085 4181cf83cf26ea2fecc18adef347d76c 91 SUPERFAMILY SSF63562 1 79 8.2E-25 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 WM46_RS20085 4181cf83cf26ea2fecc18adef347d76c 91 Gene3D G3DSA:3.90.940.10 1 91 5.9E-28 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 WM46_RS20085 4181cf83cf26ea2fecc18adef347d76c 91 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 1.7E-30 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS20085 4181cf83cf26ea2fecc18adef347d76c 91 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 16.321 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS20085 4181cf83cf26ea2fecc18adef347d76c 91 SMART SM01409 8 61 1.3E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 WM46_RS20085 4181cf83cf26ea2fecc18adef347d76c 91 Pfam PF01192 RNA polymerase Rpb6 10 59 1.9E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 Gene3D G3DSA:2.170.130.10 110 278 1.9E-18 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 Pfam PF00593 TonB dependent receptor 401 829 1.6E-29 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 816 833 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 Pfam PF07715 TonB-dependent Receptor Plug Domain 165 270 4.4E-12 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 SMART SM00965 57 109 1.6E-5 T 28-03-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 167 833 1.4E-76 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 SUPERFAMILY SSF56935 157 833 5.72E-87 T 28-03-2018 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 SUPERFAMILY SSF56935 110 124 5.72E-87 T 28-03-2018 WM46_RS15420 8e21677580be51a2682484f4102ea3cb 833 Gene3D G3DSA:2.40.170.20 285 833 1.2E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Gene3D G3DSA:2.140.10.10 704 789 3.3E-13 T 28-03-2018 WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SMART SM00564 715 748 0.04 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SMART SM00564 401 458 310.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SMART SM00564 339 380 0.012 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SMART SM00564 282 314 49.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SMART SM00564 220 251 6.4E-7 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SMART SM00564 479 512 330.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 404 425 - T 28-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 ProSitePatterns PS00363 Bacterial quinoprotein dehydrogenases signature 1. 167 195 - T 28-03-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Gene3D G3DSA:2.140.10.10 158 607 4.7E-87 T 28-03-2018 WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SUPERFAMILY SSF50998 557 792 5.1E-159 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 SUPERFAMILY SSF50998 162 521 5.1E-159 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Pfam PF01011 PQQ enzyme repeat 225 260 4.8E-9 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Pfam PF01011 PQQ enzyme repeat 442 468 1.3E-6 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Pfam PF01011 PQQ enzyme repeat 664 696 3.3E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Pfam PF01011 PQQ enzyme repeat 721 758 4.0E-6 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 Pfam PF01011 PQQ enzyme repeat 289 320 2.9E-5 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS14155 38ddd820795de09c8860cfdb56d24566 796 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 15 792 0.0 T 28-03-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 SUPERFAMILY SSF48498 84 202 1.84E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 204 2.0E-50 T 28-03-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 SUPERFAMILY SSF46689 1 67 1.1E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.5E-20 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS12430 267f7326ebeabae4426c522d1183a46c 217 Gene3D G3DSA:1.10.357.10 1 212 1.4E-40 T 28-03-2018 WM46_RS13440 fc1bad8efd2d8e768bdbd98322a450e0 332 SUPERFAMILY SSF81345 9 331 3.14E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS13440 fc1bad8efd2d8e768bdbd98322a450e0 332 Pfam PF01032 FecCD transport family 18 330 5.3E-85 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS13440 fc1bad8efd2d8e768bdbd98322a450e0 332 Gene3D G3DSA:1.10.3470.10 4 332 5.4E-58 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 6 241 5.1E-98 T 28-03-2018 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 7.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 7.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 5.8E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 Pfam PF07702 UTRA domain 96 235 4.6E-30 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 SMART SM00345 17 75 1.1E-23 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 SUPERFAMILY SSF64288 63 240 2.83E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 Gene3D G3DSA:1.10.10.10 1 76 2.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 SUPERFAMILY SSF46785 8 83 1.09E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 Gene3D G3DSA:3.40.1410.10 80 241 1.1E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS21880 1b0a0465b8034e8d75d2f4de90cece47 241 SMART SM00866 96 236 7.5E-26 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 Gene3D G3DSA:3.20.20.80 1 477 3.2E-151 T 28-03-2018 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 Pfam PF00232 Glycosyl hydrolase family 1 3 473 4.1E-130 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 413 430 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 1.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 SUPERFAMILY SSF51445 2 473 6.76E-163 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS15370 702674d2d2d4421d3d17919816d8f440 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 Gene3D G3DSA:3.30.390.10 1 131 3.0E-35 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 SUPERFAMILY SSF51604 114 363 9.04E-71 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 SMART SM00922 145 242 9.9E-22 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 28 126 1.0E-16 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 Gene3D G3DSA:3.20.20.120 132 354 3.0E-64 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 101 126 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 Pfam PF13378 Enolase C-terminal domain-like 151 356 4.0E-58 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 192 223 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS23555 46a4411ab52969ee287ccccea4627d23 379 SUPERFAMILY SSF54826 2 128 4.57E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS11430 99960a5b53f236db5a6dd9eb4dd57fb9 67 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 67 21.061 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 WM46_RS11430 99960a5b53f236db5a6dd9eb4dd57fb9 67 Pfam PF02416 mttA/Hcf106 family 4 53 2.5E-12 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 WM46_RS11430 99960a5b53f236db5a6dd9eb4dd57fb9 67 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 1.1E-20 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 WM46_RS11430 99960a5b53f236db5a6dd9eb4dd57fb9 67 Hamap MF_00903 Probable Sec-independent protein translocase protein TatE [tatE]. 1 67 28.321 T 28-03-2018 IPR024905 Sec-independent protein translocase protein TatE WM46_RS06500 303981c23cb5a3235ed588dd305243d9 297 SUPERFAMILY SSF103481 35 137 5.1E-14 T 28-03-2018 WM46_RS06500 303981c23cb5a3235ed588dd305243d9 297 Pfam PF00892 EamA-like transporter family 149 285 2.1E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS06500 303981c23cb5a3235ed588dd305243d9 297 Pfam PF00892 EamA-like transporter family 6 134 5.3E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS06500 303981c23cb5a3235ed588dd305243d9 297 SUPERFAMILY SSF103481 191 287 1.31E-9 T 28-03-2018 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 Gene3D G3DSA:1.10.10.10 226 246 0.06 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 Pfam PF02311 AraC-like ligand binding domain 33 141 3.6E-10 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 SUPERFAMILY SSF51215 13 167 1.01E-19 T 28-03-2018 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 SMART SM00342 195 278 1.9E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 Pfam PF12833 Helix-turn-helix domain 201 280 3.6E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 Gene3D G3DSA:1.10.10.60 106 225 8.4E-12 T 28-03-2018 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 232 274 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 SUPERFAMILY SSF46689 231 281 2.51E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 Gene3D G3DSA:2.60.120.10 11 91 1.1E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 SUPERFAMILY SSF46689 182 228 6.18E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 262 2.6E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 278 2.6E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS16100 f27e346da873d083c88c7e75f3b401c2 282 Gene3D G3DSA:1.10.10.60 247 282 1.8E-11 T 28-03-2018 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 Gene3D G3DSA:1.10.569.10 270 464 6.2E-26 T 28-03-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 228 685 1.9E-65 T 28-03-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 Gene3D G3DSA:1.10.599.10 465 688 9.9E-40 T 28-03-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 SUPERFAMILY SSF56228 3 210 6.67E-63 T 28-03-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 205 5.9E-69 T 28-03-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 Gene3D G3DSA:3.60.9.10 2 210 4.3E-74 T 28-03-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 SMART SM00790 5 206 3.7E-89 T 28-03-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 WM46_RS07750 36a84115e86fe8ef9ef3edd426ead12c 700 SUPERFAMILY SSF48310 212 698 6.93E-73 T 28-03-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 WM46_RS01045 7f5216c3eb002b590f069fb1bb008866 141 Gene3D G3DSA:3.40.630.30 1 72 1.6E-16 T 28-03-2018 WM46_RS01045 7f5216c3eb002b590f069fb1bb008866 141 Pfam PF00583 Acetyltransferase (GNAT) family 18 123 2.2E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS01045 7f5216c3eb002b590f069fb1bb008866 141 PIRSF PIRSF037663 1 130 6.1E-11 T 28-03-2018 IPR017255 Acetyltransferase, GNAT, predicted WM46_RS01045 7f5216c3eb002b590f069fb1bb008866 141 Hamap MF_01127 Acetyltransferase YpeA [ypeA]. 1 141 47.6 T 28-03-2018 IPR023072 Acetyltransferase, YpeA GO:0016747 WM46_RS01045 7f5216c3eb002b590f069fb1bb008866 141 Gene3D G3DSA:3.40.630.30 73 129 7.6E-16 T 28-03-2018 WM46_RS01045 7f5216c3eb002b590f069fb1bb008866 141 SUPERFAMILY SSF55729 1 128 7.69E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 289 1.4E-146 T 28-03-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Gene3D G3DSA:3.30.70.20 153 256 3.5E-23 T 28-03-2018 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Gene3D G3DSA:3.30.70.20 13 42 0.0052 T 28-03-2018 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Gene3D G3DSA:3.30.70.20 114 152 2.5E-16 T 28-03-2018 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 SUPERFAMILY SSF54862 28 272 4.08E-73 T 28-03-2018 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 PIRSF PIRSF036298 1 301 1.5E-166 T 28-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 288 1.2E-21 T 28-03-2018 IPR015246 Formate dehydrogenase, transmembrane WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Pfam PF13247 4Fe-4S dicluster domain 92 188 4.8E-25 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Gene3D G3DSA:3.30.70.20 43 113 1.2E-21 T 28-03-2018 WM46_RS18690 7268a163e4ffc9d73a97f2050f866904 301 Gene3D G3DSA:1.20.5.480 257 291 3.2E-22 T 28-03-2018 WM46_RS10945 5d36358db0869639ac1f3ab49975a3e1 258 Gene3D G3DSA:3.20.20.150 1 258 9.9E-51 T 28-03-2018 WM46_RS10945 5d36358db0869639ac1f3ab49975a3e1 258 SUPERFAMILY SSF51658 1 258 2.11E-73 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS10945 5d36358db0869639ac1f3ab49975a3e1 258 PIRSF PIRSF006241 1 258 3.2E-83 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 WM46_RS10945 5d36358db0869639ac1f3ab49975a3e1 258 Pfam PF01261 Xylose isomerase-like TIM barrel 21 218 1.1E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS00210 8cdff0a08b8af78375fda99adb4430c8 452 Pfam PF03929 PepSY-associated TM region 15 382 2.7E-56 T 28-03-2018 IPR005625 PepSY-associated TM protein WM46_RS09015 19d502fe8f1b3471b4c799d69a4a420b 172 Pfam PF05638 Type VI secretion system effector, Hcp 8 155 5.0E-31 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09015 19d502fe8f1b3471b4c799d69a4a420b 172 SUPERFAMILY SSF141452 3 168 1.96E-37 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09015 19d502fe8f1b3471b4c799d69a4a420b 172 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 168 2.7E-62 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS09015 19d502fe8f1b3471b4c799d69a4a420b 172 Gene3D G3DSA:2.30.110.20 2 172 6.3E-48 T 28-03-2018 IPR008514 Type VI secretion system effector, Hcp WM46_RS05460 8a650c06b24d145f6978754a1b15eeff 539 Pfam PF00069 Protein kinase domain 36 305 2.7E-21 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM46_RS05460 8a650c06b24d145f6978754a1b15eeff 539 Gene3D G3DSA:1.10.510.10 127 319 3.1E-21 T 28-03-2018 WM46_RS05460 8a650c06b24d145f6978754a1b15eeff 539 SUPERFAMILY SSF56112 36 306 3.03E-32 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS05460 8a650c06b24d145f6978754a1b15eeff 539 Gene3D G3DSA:3.30.200.20 17 126 6.4E-4 T 28-03-2018 WM46_RS05460 8a650c06b24d145f6978754a1b15eeff 539 SMART SM00220 29 314 8.9E-10 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 WM46_RS13315 b1cd63a4a15f661682aa59550f5ffbbb 328 Gene3D G3DSA:3.40.50.1980 155 321 1.8E-22 T 28-03-2018 WM46_RS13315 b1cd63a4a15f661682aa59550f5ffbbb 328 SUPERFAMILY SSF53807 32 312 9.03E-38 T 28-03-2018 WM46_RS13315 b1cd63a4a15f661682aa59550f5ffbbb 328 Gene3D G3DSA:3.40.50.1980 26 154 9.2E-21 T 28-03-2018 WM46_RS13315 b1cd63a4a15f661682aa59550f5ffbbb 328 Pfam PF01497 Periplasmic binding protein 55 293 1.1E-19 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS21420 0f0b60a4f248954584e66f64c2eb06d3 135 Pfam PF03610 PTS system fructose IIA component 7 113 2.0E-16 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS21420 0f0b60a4f248954584e66f64c2eb06d3 135 Gene3D G3DSA:3.40.50.510 1 134 1.7E-26 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS21420 0f0b60a4f248954584e66f64c2eb06d3 135 SUPERFAMILY SSF53062 1 125 2.09E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS21420 0f0b60a4f248954584e66f64c2eb06d3 135 TIGRFAM TIGR00824 EIIA-man: PTS system, mannose/fructose/sorbose family, IIA component 1 114 2.2E-44 T 28-03-2018 IPR013789 Phosphotransferase system, mannose family IIA component GO:0005737|GO:0008643|GO:0016773 WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 Pfam PF00206 Lyase 14 312 1.6E-83 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 SUPERFAMILY SSF48557 10 454 9.11E-108 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 Gene3D G3DSA:1.10.40.30 391 445 6.9E-32 T 28-03-2018 WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 2.8E-52 T 28-03-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 2.0E-17 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 2.0E-17 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 2.0E-17 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 2.0E-17 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 Gene3D G3DSA:1.10.275.10 1 117 1.1E-43 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 3.5E-156 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 Gene3D G3DSA:1.20.200.10 118 390 4.8E-84 T 28-03-2018 WM46_RS08490 98b079b81439cd6e08404fdb6708a362 456 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 SUPERFAMILY SSF69189 284 377 7.65E-23 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 Gene3D G3DSA:3.40.710.10 15 301 1.9E-56 T 28-03-2018 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 Gene3D G3DSA:2.60.410.10 302 375 1.1E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 284 375 7.7E-21 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 SMART SM00936 284 375 9.5E-29 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 SUPERFAMILY SSF56601 10 283 7.01E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 264 8.2E-96 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 1.7E-17 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 1.7E-17 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS03405 48fec1f69d0bb1db12357e099e360013 390 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 1.7E-17 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 TIGRFAM TIGR02405 trehalos_R_Ecol: trehalose operon repressor 4 314 1.3E-171 T 28-03-2018 IPR012771 Trehalose operon repressor GO:0003677|GO:0005991|GO:0045892 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 SUPERFAMILY SSF53822 63 314 2.54E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 Pfam PF13377 Periplasmic binding protein-like domain 168 312 6.1E-20 T 28-03-2018 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 Gene3D G3DSA:1.10.260.40 5 56 1.7E-21 T 28-03-2018 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 6.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 6.2E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 Gene3D G3DSA:3.40.50.2300 174 304 5.0E-23 T 28-03-2018 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 Gene3D G3DSA:3.40.50.2300 57 173 8.3E-19 T 28-03-2018 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 SUPERFAMILY SSF47413 3 60 1.33E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 4.4E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 WM46_RS23280 0f0c54645f627856c0588986b4ba2f14 315 SMART SM00354 4 74 3.5E-33 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 SUPERFAMILY SSF46785 9 148 5.37E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 2.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 Pfam PF01047 MarR family 36 94 6.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 Gene3D G3DSA:1.10.10.10 8 154 2.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23880 fb626ec685fa6da52d4643dceacd38cc 154 SMART SM00347 29 130 1.4E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS01885 0dfb74cdd536b36f09e80456905f118a 111 SUPERFAMILY SSF103481 6 107 4.45E-15 T 28-03-2018 WM46_RS01885 0dfb74cdd536b36f09e80456905f118a 111 Hamap MF_01869 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE [arnE]. 1 111 28.916 T 28-03-2018 IPR022883 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase, subunit ArnE WM46_RS01885 0dfb74cdd536b36f09e80456905f118a 111 Pfam PF00892 EamA-like transporter family 6 107 1.3E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS17915 cbfcb0fec3da5b9b7542f10b36e38126 695 Gene3D G3DSA:3.20.20.80 139 687 1.3E-155 T 28-03-2018 WM46_RS17915 cbfcb0fec3da5b9b7542f10b36e38126 695 SUPERFAMILY SSF51445 128 561 7.98E-146 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS17915 cbfcb0fec3da5b9b7542f10b36e38126 695 SUPERFAMILY SSF51445 600 687 7.98E-146 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS17915 cbfcb0fec3da5b9b7542f10b36e38126 695 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 101 686 5.2E-282 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 WM46_RS17915 cbfcb0fec3da5b9b7542f10b36e38126 695 Pfam PF02446 4-alpha-glucanotransferase 149 665 2.6E-130 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 Gene3D G3DSA:1.10.10.10 116 187 2.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 Pfam PF04542 Sigma-70 region 2 25 91 3.3E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 Pfam PF08281 Sigma-70, region 4 129 180 4.5E-19 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 46 77 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 189 6.8E-99 T 28-03-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 Gene3D G3DSA:1.10.1740.10 1 115 6.7E-31 T 28-03-2018 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 SUPERFAMILY SSF88946 2 105 2.98E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 183 6.2E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS00375 f3245c5f3693cc42af24c36c259d8cb7 191 SUPERFAMILY SSF88659 122 183 9.53E-19 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 Gene3D G3DSA:3.40.710.10 27 310 1.0E-46 T 28-03-2018 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 Gene3D G3DSA:2.60.410.10 311 382 5.4E-17 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 292 383 8.8E-24 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 SUPERFAMILY SSF56601 16 292 6.62E-75 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 SMART SM00936 292 383 1.9E-32 T 28-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 SUPERFAMILY SSF69189 292 385 5.1E-23 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 39 272 1.2E-100 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 5.7E-17 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 131 148 5.7E-17 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS11405 577cc4c37202ea98307f3f1b5028b0c6 403 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 5.7E-17 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 Pfam PF00593 TonB dependent receptor 290 694 1.2E-38 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 681 698 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 Gene3D G3DSA:2.170.130.10 48 195 5.3E-19 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 65 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 Gene3D G3DSA:2.40.170.20 196 698 1.3E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 Pfam PF07715 TonB-dependent Receptor Plug Domain 72 186 7.5E-11 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS13300 9cfade1b8f6b56198479e542f523af86 698 SUPERFAMILY SSF56935 50 698 4.03E-98 T 28-03-2018 WM46_RS16150 dfc9312fc6085517284d59ec0d9fb43f 262 SUPERFAMILY SSF53213 5 261 1.7E-92 T 28-03-2018 WM46_RS16150 dfc9312fc6085517284d59ec0d9fb43f 262 PIRSF PIRSF006157 1 262 1.4E-92 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 WM46_RS16150 dfc9312fc6085517284d59ec0d9fb43f 262 Gene3D G3DSA:3.40.830.10 1 262 4.2E-84 T 28-03-2018 WM46_RS16150 dfc9312fc6085517284d59ec0d9fb43f 262 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 259 1.2E-26 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 8 429 1.8E-186 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Gene3D G3DSA:3.30.70.1170 173 230 9.7E-18 T 28-03-2018 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Gene3D G3DSA:1.10.287.730 146 172 3.3E-15 T 28-03-2018 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Pfam PF01029 NusB family 7 127 3.7E-25 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 316 327 - T 28-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 1.3E-31 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 411 428 1.3E-31 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 251 261 1.3E-31 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 236 1.3E-31 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 383 1.3E-31 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 SUPERFAMILY SSF53335 145 428 1.52E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Gene3D G3DSA:1.10.940.10 1 145 1.6E-32 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Pfam PF01189 16S rRNA methyltransferase RsmB/F 240 426 9.8E-76 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 SUPERFAMILY SSF48013 6 149 6.21E-35 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Gene3D G3DSA:3.40.50.150 231 429 2.4E-53 T 28-03-2018 WM46_RS17385 90303224fd7e7e18c1f1e0cf6a335159 429 Hamap MF_01856 Ribosomal RNA small subunit methyltransferase B [rsmB]. 1 429 72.213 T 28-03-2018 IPR023541 rRNA small subunit methyltransferase B, enterobacteriaceae GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 Pfam PF00701 Dihydrodipicolinate synthetase family 13 305 1.9E-112 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 SUPERFAMILY SSF51569 10 308 8.37E-87 T 28-03-2018 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 PIRSF PIRSF001365 9 311 3.5E-93 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 50 67 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 2.2E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 140 157 2.2E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 2.2E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 83 101 2.2E-23 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 SMART SM01130 13 307 5.5E-104 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 145 176 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM46_RS09525 e130dc4d4c376c493ae369bc2e8794d0 311 Gene3D G3DSA:3.20.20.70 9 310 5.7E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS23010 70d2c0cc3000cdc611e33c90f5dccdb1 216 Pfam PF04225 Opacity-associated protein A LysM-like domain 131 215 9.2E-35 T 28-03-2018 IPR007340 Opacity-associated protein A WM46_RS23010 70d2c0cc3000cdc611e33c90f5dccdb1 216 Pfam PF08525 Opacity-associated protein A N-terminal motif 23 50 5.0E-9 T 28-03-2018 IPR013731 Opacity-associated protein A, N-terminal WM46_RS06630 b0b9e1ee08d4fb501fb210f0f3e462a1 191 Pfam PF01381 Helix-turn-helix 16 69 1.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS06630 b0b9e1ee08d4fb501fb210f0f3e462a1 191 SUPERFAMILY SSF51182 56 185 6.48E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS06630 b0b9e1ee08d4fb501fb210f0f3e462a1 191 Gene3D G3DSA:1.10.260.40 1 74 2.0E-17 T 28-03-2018 WM46_RS06630 b0b9e1ee08d4fb501fb210f0f3e462a1 191 SUPERFAMILY SSF47413 8 74 6.7E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS06630 b0b9e1ee08d4fb501fb210f0f3e462a1 191 Gene3D G3DSA:2.60.120.10 75 190 2.9E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS06630 b0b9e1ee08d4fb501fb210f0f3e462a1 191 SMART SM00530 15 70 9.2E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 SMART SM00420 6 58 2.1E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 7.3E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 Gene3D G3DSA:3.40.50.1360 66 235 2.9E-38 T 28-03-2018 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 SMART SM01134 72 233 3.1E-72 T 28-03-2018 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 Gene3D G3DSA:1.10.10.10 1 61 1.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 Pfam PF00455 DeoR C terminal sensor domain 74 231 2.1E-52 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 SUPERFAMILY SSF100950 76 234 4.19E-36 T 28-03-2018 WM46_RS25480 684d248bb2fe1ea36602e99ad464e900 257 SUPERFAMILY SSF46785 4 63 3.53E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 SUPERFAMILY SSF46785 8 118 2.13E-48 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 Pfam PF03882 MukF winged-helix domain 3 117 8.3E-58 T 28-03-2018 IPR033439 Chromosome partition protein MukF, winged-helix domain WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 Gene3D G3DSA:1.10.10.10 24 116 2.4E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 PIRSF PIRSF018282 1 440 1.8E-244 T 28-03-2018 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 SUPERFAMILY SSF140570 119 281 1.7E-77 T 28-03-2018 IPR033440 Chromosome partition protein MukF, middle domain WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 Pfam PF17192 MukF middle domain 121 281 1.5E-84 T 28-03-2018 IPR033440 Chromosome partition protein MukF, middle domain WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 Hamap MF_01803 Chromosome partition protein MukF [mukF]. 1 440 57.675 T 28-03-2018 IPR005582 Chromosome partition protein MukF GO:0005509|GO:0006260|GO:0007059 WM46_RS09795 3ac844f5cff10980eb0d6feb474a3f33 440 Pfam PF17193 MukF C-terminal domain 283 440 2.8E-80 T 28-03-2018 IPR033441 Chromosome partition protein MukF, C-terminal domain WM46_RS24965 9bf374fb6322f2252b431df4963e70f4 401 Gene3D G3DSA:3.90.1150.10 279 395 1.3E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS24965 9bf374fb6322f2252b431df4963e70f4 401 Gene3D G3DSA:3.40.640.10 31 278 1.2E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS24965 9bf374fb6322f2252b431df4963e70f4 401 Pfam PF00266 Aminotransferase class-V 21 388 1.3E-139 T 28-03-2018 IPR000192 Aminotransferase class V domain WM46_RS24965 9bf374fb6322f2252b431df4963e70f4 401 SUPERFAMILY SSF53383 5 397 3.19E-109 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS24965 9bf374fb6322f2252b431df4963e70f4 401 TIGRFAM TIGR03392 FeS_syn_CsdA: cysteine desulfurase, catalytic subunit CsdA 4 401 3.0E-229 T 28-03-2018 IPR022471 Cysteine desulphurase, catalytic subunit, CsdA GO:0016226|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 WM46_RS24965 9bf374fb6322f2252b431df4963e70f4 401 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 213 232 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site WM46_RS11755 911829114be8b23e5ff6278c4bbaf6b5 377 SMART SM00849 108 314 0.0013 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS11755 911829114be8b23e5ff6278c4bbaf6b5 377 Pfam PF12706 Beta-lactamase superfamily domain 120 314 2.1E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS11755 911829114be8b23e5ff6278c4bbaf6b5 377 PIRSF PIRSF038896 12 354 2.5E-87 T 28-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 WM46_RS11755 911829114be8b23e5ff6278c4bbaf6b5 377 SUPERFAMILY SSF56281 206 352 4.72E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS11755 911829114be8b23e5ff6278c4bbaf6b5 377 SUPERFAMILY SSF56281 104 179 4.72E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS11755 911829114be8b23e5ff6278c4bbaf6b5 377 Gene3D G3DSA:3.60.15.10 75 368 4.9E-44 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS12530 d7d3b265e3ffd7d2c0ae0e2a1d7c91a5 356 Pfam PF00589 Phage integrase family 193 342 1.6E-15 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS12530 d7d3b265e3ffd7d2c0ae0e2a1d7c91a5 356 SUPERFAMILY SSF56349 128 343 5.0E-35 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS12530 d7d3b265e3ffd7d2c0ae0e2a1d7c91a5 356 Gene3D G3DSA:1.10.443.10 171 349 1.2E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS10450 5b68f5fbb06142a0bdacfcc7b130fcd3 86 Pfam PF07338 Protein of unknown function (DUF1471) 34 86 2.8E-17 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS10450 5b68f5fbb06142a0bdacfcc7b130fcd3 86 SUPERFAMILY SSF159871 3 86 2.62E-25 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS10450 5b68f5fbb06142a0bdacfcc7b130fcd3 86 Gene3D G3DSA:3.30.1660.10 22 86 3.0E-22 T 28-03-2018 IPR025543 Dodecin-like WM46_RS00385 784e9ffd8b3b59de1651083eabb20bbc 318 Pfam PF03888 MucB/RseB N-terminal domain 28 208 3.1E-61 T 28-03-2018 IPR033434 MucB/RseB, N-terminal WM46_RS00385 784e9ffd8b3b59de1651083eabb20bbc 318 Pfam PF17188 MucB/RseB C-terminal domain 217 313 2.0E-28 T 28-03-2018 IPR033436 MucB/RseB, C-terminal WM46_RS00385 784e9ffd8b3b59de1651083eabb20bbc 318 Gene3D G3DSA:2.50.20.10 19 289 5.2E-20 T 28-03-2018 WM46_RS00385 784e9ffd8b3b59de1651083eabb20bbc 318 PIRSF PIRSF005427 1 318 8.7E-100 T 28-03-2018 IPR005588 MucB/RseB WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 SMART SM00382 26 212 3.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 Pfam PF00571 CBS domain 264 306 7.7E-5 T 28-03-2018 IPR000644 CBS domain WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 Gene3D G3DSA:3.10.580.10 249 315 1.7E-7 T 28-03-2018 WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 SUPERFAMILY SSF52540 1 239 1.64E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 Gene3D G3DSA:3.40.50.300 1 248 2.7E-72 T 28-03-2018 WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 Pfam PF00005 ABC transporter 18 162 1.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 SUPERFAMILY SSF54631 249 312 4.72E-8 T 28-03-2018 WM46_RS02585 04a08891836e1df0bf5af40b2141c77f 315 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 SUPERFAMILY SSF81296 11 103 1.07E-5 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 SUPERFAMILY SSF51445 117 530 1.45E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 Pfam PF00128 Alpha amylase, catalytic domain 177 493 2.5E-86 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 Gene3D G3DSA:2.60.40.1180 552 602 0.0017 T 28-03-2018 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 Gene3D G3DSA:3.20.20.80 513 551 1.8E-8 T 28-03-2018 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 SMART SM00642 127 521 2.1E-86 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 PIRSF PIRSF036918 1 604 2.7E-237 T 28-03-2018 IPR017069 Maltodextrin glucosidase GO:0004558|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.20|KEGG: 00500+3.2.1.20|MetaCyc: PWY-842 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 Gene3D G3DSA:3.20.20.80 115 512 2.0E-85 T 28-03-2018 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 Gene3D G3DSA:2.60.40.10 5 111 2.9E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 SUPERFAMILY SSF51011 530 603 8.74E-9 T 28-03-2018 WM46_RS12895 8f9558f3082f385e858249985fa1b785 605 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 104 1.4E-6 T 28-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 WM46_RS09265 de216e28c9d90666bf95132b530259f4 336 Gene3D G3DSA:3.30.420.40 1 184 9.7E-6 T 28-03-2018 WM46_RS09265 de216e28c9d90666bf95132b530259f4 336 Pfam PF05035 2-keto-3-deoxy-galactonokinase 6 300 1.5E-34 T 28-03-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 430 1.9E-207 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 Gene3D G3DSA:3.40.440.10 152 266 2.6E-27 T 28-03-2018 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 Gene3D G3DSA:3.40.440.10 1 151 7.8E-54 T 28-03-2018 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 SMART SM00788 4 425 3.8E-302 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 Gene3D G3DSA:3.90.170.10 267 432 2.3E-66 T 28-03-2018 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 SUPERFAMILY SSF52540 3 431 1.81E-180 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 218.325 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM46_RS22910 599d77a52fab25131dc332a80d6eb154 432 Pfam PF00709 Adenylosuccinate synthetase 5 423 5.5E-178 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 28-03-2018 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 SUPERFAMILY SSF47413 10 67 7.41E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 Pfam PF13377 Periplasmic binding protein-like domain 176 337 2.8E-44 T 28-03-2018 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 Gene3D G3DSA:1.10.260.40 10 62 1.3E-17 T 28-03-2018 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 SUPERFAMILY SSF53822 68 338 5.89E-91 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 SMART SM00354 9 79 2.0E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 2.4E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 Gene3D G3DSA:3.40.50.2300 63 183 3.2E-28 T 28-03-2018 WM46_RS18390 e8f8e5a9b966ccd5f6f0367f803845eb 341 Gene3D G3DSA:3.40.50.2300 184 320 2.6E-47 T 28-03-2018 WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 9 602 1.1E-196 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 SUPERFAMILY SSF52540 281 378 1.29E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 SUPERFAMILY SSF52540 434 602 1.29E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 Gene3D G3DSA:3.40.50.300 111 355 6.5E-64 T 28-03-2018 WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 SUPERFAMILY SSF52540 6 360 7.62E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 Pfam PF13538 UvrD-like helicase C-terminal domain 534 579 7.3E-15 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 Gene3D G3DSA:3.40.50.300 469 593 4.7E-23 T 28-03-2018 WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 Gene3D G3DSA:3.40.50.300 365 468 2.4E-18 T 28-03-2018 WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 16 602 53.678 T 28-03-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 WM46_RS24915 fe19dfe6c8c02fe08813834600f551af 605 Pfam PF13604 AAA domain 155 315 6.9E-31 T 28-03-2018 WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 Gene3D G3DSA:3.20.20.140 73 481 3.8E-35 T 28-03-2018 WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 SUPERFAMILY SSF51556 63 125 3.86E-45 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 SUPERFAMILY SSF51556 205 496 3.86E-45 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 SUPERFAMILY SSF51338 2 64 9.22E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 SUPERFAMILY SSF51338 495 545 9.22E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 Pfam PF07969 Amidohydrolase family 52 536 7.7E-124 T 28-03-2018 IPR013108 Amidohydrolase 3 WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 Gene3D G3DSA:2.30.40.10 4 72 8.3E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS12875 bda4e31cc71c2d2cf240fbc72e2fd0c8 622 Gene3D G3DSA:2.30.40.10 482 545 0.0072 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 3.4E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 3.4E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 3.4E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 3.4E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 3.4E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 3.4E-39 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 Pfam PF03477 ATP cone domain 6 92 2.1E-15 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 SUPERFAMILY SSF48168 10 221 2.88E-73 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 Gene3D G3DSA:3.20.70.20 122 739 1.7E-148 T 28-03-2018 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 SUPERFAMILY SSF51998 222 740 2.26E-169 T 28-03-2018 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 2.6E-120 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 5.0E-179 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS02000 d4f9cdbcdd4de66e577a373006fd94d4 761 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 219 2.7E-12 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 Gene3D G3DSA:2.60.40.1090 170 319 0.081 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 Gene3D G3DSA:2.60.40.1090 20 161 3.4E-6 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 SMART SM00972 93 157 0.058 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 SMART SM00972 253 316 7.7E-16 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 Pfam PF05229 Spore Coat Protein U domain 10 155 6.3E-10 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 Pfam PF05229 Spore Coat Protein U domain 181 315 2.7E-31 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04160 2a2257f5ed58d54838c57f95c3b2a3a5 319 SUPERFAMILY SSF49401 19 161 2.94E-5 T 28-03-2018 IPR008966 Adhesion domain WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 15 512 1.7E-267 T 28-03-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 Gene3D G3DSA:3.40.50.1100 149 330 3.0E-45 T 28-03-2018 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 SUPERFAMILY SSF55021 336 423 3.51E-28 T 28-03-2018 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 316 5.5E-78 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 53 66 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 SUPERFAMILY SSF55021 420 512 8.01E-26 T 28-03-2018 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 Gene3D G3DSA:3.40.1020.10 338 513 1.4E-71 T 28-03-2018 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 SUPERFAMILY SSF53686 15 365 1.13E-100 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 Gene3D G3DSA:3.40.50.1100 37 148 3.2E-30 T 28-03-2018 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 425 512 8.7E-28 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 WM46_RS19325 26ee9f33402ceace4f9d1c13b9bcc360 514 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 419 9.3E-29 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 SUPERFAMILY SSF50891 1 162 4.82E-60 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 PIRSF PIRSF001467 1 164 3.0E-29 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 1.0E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 1.0E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 1.0E-11 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 1 161 3.4E-48 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 Gene3D G3DSA:2.40.100.10 1 164 8.4E-53 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS12215 6eaae5127e090900c0702a56ec4c8d71 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 80 94 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 374 2.0E-48 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 SUPERFAMILY SSF53686 6 390 6.55E-141 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 2 391 49.129 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 8 389 1.6E-185 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 Gene3D G3DSA:3.40.50.1100 198 395 1.0E-36 T 28-03-2018 WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 Gene3D G3DSA:3.40.50.1100 9 197 1.4E-42 T 28-03-2018 WM46_RS09495 bc077ab02b1ac27bba42838ee6eb5646 397 PIRSF PIRSF001413 2 397 2.0E-167 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 Gene3D G3DSA:3.30.70.580 67 146 2.0E-17 T 28-03-2018 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 Gene3D G3DSA:3.10.290.10 5 66 8.9E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 SUPERFAMILY SSF55174 9 63 2.02E-13 T 28-03-2018 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 74 227 1.2E-54 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 Pfam PF00849 RNA pseudouridylate synthase 70 196 1.2E-15 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 Gene3D G3DSA:3.30.70.1560 147 208 2.7E-24 T 28-03-2018 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 105 119 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 Pfam PF01479 S4 domain 9 53 7.5E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 SMART SM00363 8 64 1.4E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS21435 2096d52d1ac099563d0c06faad8f9c84 292 SUPERFAMILY SSF55120 70 230 5.76E-39 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS02835 b46b043d40b3b8928747b78a46d55304 181 Gene3D G3DSA:2.160.10.10 22 181 5.1E-33 T 28-03-2018 WM46_RS02835 b46b043d40b3b8928747b78a46d55304 181 TIGRFAM TIGR04008 WcaF: colanic acid biosynthesis acetyltransferase WcaF 1 180 1.9E-120 T 28-03-2018 IPR024005 Colanic acid biosynthesis, acetyltransferase, WcaF WM46_RS02835 b46b043d40b3b8928747b78a46d55304 181 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 133 161 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS02835 b46b043d40b3b8928747b78a46d55304 181 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 125 157 4.4E-7 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS02835 b46b043d40b3b8928747b78a46d55304 181 SUPERFAMILY SSF51161 20 180 1.94E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 67 298 6.7E-59 T 28-03-2018 WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 187 195 1.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 146 1.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 207 226 1.8E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 194 222 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 SUPERFAMILY SSF51735 57 298 1.4E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 Gene3D G3DSA:3.40.50.720 10 301 1.4E-76 T 28-03-2018 WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 146 4.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 245 4.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 59 76 4.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 263 283 4.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 226 4.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11985 e3ea0b5d56a116e8a47b455a2cc918a4 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 197 4.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS02815 9949aae85e397c812cad02fc1c18e606 162 Gene3D G3DSA:2.160.10.10 30 160 6.0E-25 T 28-03-2018 WM46_RS02815 9949aae85e397c812cad02fc1c18e606 162 SUPERFAMILY SSF51161 11 158 5.68E-32 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS02815 9949aae85e397c812cad02fc1c18e606 162 PIRSF PIRSF000441 2 161 4.9E-45 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 WM46_RS02815 9949aae85e397c812cad02fc1c18e606 162 TIGRFAM TIGR04016 WcaB: colanic acid biosynthesis acetyltransferase WcaB 17 162 1.9E-94 T 28-03-2018 IPR024027 Colanic acid biosynthesis, acetyltransferase, WcaB GO:0016747 WM46_RS02815 9949aae85e397c812cad02fc1c18e606 162 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 117 145 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS02815 9949aae85e397c812cad02fc1c18e606 162 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 141 3.1E-8 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS25515 3d3b86730060209de51dbcccfb38cd23 165 Pfam PF02464 Competence-damaged protein 8 160 3.3E-60 T 28-03-2018 IPR008136 CinA, C-terminal WM46_RS25515 3d3b86730060209de51dbcccfb38cd23 165 Gene3D G3DSA:3.90.950.20 1 165 2.1E-60 T 28-03-2018 WM46_RS25515 3d3b86730060209de51dbcccfb38cd23 165 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 14 158 4.2E-62 T 28-03-2018 IPR008136 CinA, C-terminal WM46_RS25515 3d3b86730060209de51dbcccfb38cd23 165 SUPERFAMILY SSF142433 3 161 8.89E-59 T 28-03-2018 IPR008136 CinA, C-terminal WM46_RS21730 e92dc63deca86d2cbf260caecf211876 163 SMART SM01321 9 119 6.9E-28 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM46_RS21730 e92dc63deca86d2cbf260caecf211876 163 Gene3D G3DSA:3.30.70.1290 1 125 9.2E-29 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM46_RS21730 e92dc63deca86d2cbf260caecf211876 163 SUPERFAMILY SSF143422 1 125 1.19E-29 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM46_RS21730 e92dc63deca86d2cbf260caecf211876 163 Pfam PF01797 Transposase IS200 like 17 103 3.6E-5 T 28-03-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 WM46_RS20170 6b4ad3137b8bd3b0d1f9e46fc173be28 356 TIGRFAM TIGR02201 heptsyl_trn_III: putative lipopolysaccharide heptosyltransferase III 7 344 1.7E-152 T 28-03-2018 IPR011916 Lipopolysaccharide heptosyltransferase III, putative WM46_RS20170 6b4ad3137b8bd3b0d1f9e46fc173be28 356 SUPERFAMILY SSF53756 6 344 2.83E-82 T 28-03-2018 WM46_RS20170 6b4ad3137b8bd3b0d1f9e46fc173be28 356 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 77 326 5.8E-69 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 WM46_RS20170 6b4ad3137b8bd3b0d1f9e46fc173be28 356 Gene3D G3DSA:3.40.50.2000 1 162 2.7E-33 T 28-03-2018 WM46_RS20170 6b4ad3137b8bd3b0d1f9e46fc173be28 356 Gene3D G3DSA:3.40.50.2000 164 347 3.7E-42 T 28-03-2018 WM46_RS17805 a6247de332af9b469dae224093a13277 179 Pfam PF05137 Fimbrial assembly protein (PilN) 99 166 1.4E-7 T 28-03-2018 IPR007813 Fimbrial assembly PilN WM46_RS10150 4f0cae16ef24cf3c3f2170f45ccd5760 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 311 8.0E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10150 4f0cae16ef24cf3c3f2170f45ccd5760 317 SUPERFAMILY SSF161098 27 308 1.7E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10150 4f0cae16ef24cf3c3f2170f45ccd5760 317 Gene3D G3DSA:1.10.3720.10 30 311 1.5E-41 T 28-03-2018 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 36 219 33.885 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 98 114 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 40 220 3.9E-86 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 Pfam PF01227 GTP cyclohydrolase I 41 218 1.9E-63 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 Gene3D G3DSA:3.30.1130.10 89 221 8.2E-47 T 28-03-2018 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 SUPERFAMILY SSF55620 4 221 5.71E-77 T 28-03-2018 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 Gene3D G3DSA:1.10.286.10 7 85 6.3E-21 T 28-03-2018 WM46_RS02440 25037f46fb37d99d3d337098b4d5c578 222 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 146 156 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 256 5.1E-96 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 3 11 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 Gene3D G3DSA:3.20.20.140 1 265 7.1E-81 T 28-03-2018 WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 SUPERFAMILY SSF51556 1 260 7.59E-88 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 Pfam PF01026 TatD related DNase 4 255 1.2E-76 T 28-03-2018 IPR001130 TatD family GO:0016788 WM46_RS08645 a824aacd4f2c3c10d256c017e017dc97 265 PIRSF PIRSF005902 1 259 1.3E-75 T 28-03-2018 IPR001130 TatD family GO:0016788 WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 Pfam PF01050 Mannose-6-phosphate isomerase 323 473 4.6E-75 T 28-03-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 Gene3D G3DSA:3.90.550.10 5 345 8.0E-95 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 Pfam PF00483 Nucleotidyl transferase 8 295 5.8E-79 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 Gene3D G3DSA:2.60.120.10 346 455 1.5E-29 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 6 477 8.2E-243 T 28-03-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 SUPERFAMILY SSF51182 193 477 1.84E-88 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS02860 718b33605dc7cd49ac3a2eb781c65f4f 478 SUPERFAMILY SSF53448 6 290 7.51E-74 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS06960 21515c1ad03a543e1ca35ec7d35ab9b1 105 ProDom PD071248 DNA-BINDING SINGLE STRANDED DNA PHAGE PROTIEN GPV HELIX-DESTABILIZING SINGLE-STRANDED REPLICATION 5 104 2.0E-51 T 28-03-2018 IPR035411 Putative DNA-Binding protein G5P WM46_RS06960 21515c1ad03a543e1ca35ec7d35ab9b1 105 Pfam PF17426 Putative Gamma DNA binding protein G5P 3 104 3.9E-40 T 28-03-2018 IPR035411 Putative DNA-Binding protein G5P WM46_RS17450 389919749e70ffc67e9bf46e53468622 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.9E-51 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17450 389919749e70ffc67e9bf46e53468622 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 3.7E-32 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P WM46_RS17450 389919749e70ffc67e9bf46e53468622 144 Gene3D G3DSA:3.100.10.10 42 144 9.4E-25 T 28-03-2018 WM46_RS17450 389919749e70ffc67e9bf46e53468622 144 SUPERFAMILY SSF52080 4 143 1.83E-46 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P WM46_RS17450 389919749e70ffc67e9bf46e53468622 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17450 389919749e70ffc67e9bf46e53468622 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 19.536 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 WM46_RS04570 a5c97bafcf9f03460aacf69a433aab73 136 Gene3D G3DSA:1.10.10.10 1 79 6.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01460 54a6564e8e95fa6cbc324fe9489cdc0b 251 PRINTS PR01805 VacJ lipoprotein signature 30 43 5.6E-35 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 WM46_RS01460 54a6564e8e95fa6cbc324fe9489cdc0b 251 PRINTS PR01805 VacJ lipoprotein signature 48 64 5.6E-35 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 WM46_RS01460 54a6564e8e95fa6cbc324fe9489cdc0b 251 PRINTS PR01805 VacJ lipoprotein signature 138 155 5.6E-35 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 WM46_RS01460 54a6564e8e95fa6cbc324fe9489cdc0b 251 PRINTS PR01805 VacJ lipoprotein signature 99 116 5.6E-35 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 WM46_RS01460 54a6564e8e95fa6cbc324fe9489cdc0b 251 Pfam PF04333 MlaA lipoprotein 29 222 1.4E-66 T 28-03-2018 IPR007428 MlaA lipoprotein GO:0016020 WM46_RS08170 1fc194388860046f7b094098a6decd4e 161 Pfam PF07813 LTXXQ motif family protein 46 141 3.0E-23 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 WM46_RS08170 1fc194388860046f7b094098a6decd4e 161 PIRSF PIRSF034445 1 152 3.9E-31 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 SUPERFAMILY SSF46689 12 61 1.03E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 64 106 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 SUPERFAMILY SSF46689 64 112 6.27E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 Gene3D G3DSA:1.10.10.60 1 64 6.9E-19 T 28-03-2018 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 Gene3D G3DSA:1.10.10.60 65 128 1.6E-13 T 28-03-2018 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 SMART SM00342 27 110 3.0E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS07080 bf2491c8b62eb0f8c1a93f71bef3ca42 128 Pfam PF12833 Helix-turn-helix domain 34 110 7.3E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 Gene3D G3DSA:2.70.70.10 280 437 9.2E-46 T 28-03-2018 WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 SMART SM00257 97 142 3.1E-6 T 28-03-2018 IPR018392 LysM domain WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 SUPERFAMILY SSF51261 168 408 5.75E-69 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 Pfam PF01551 Peptidase family M23 313 407 2.0E-32 T 28-03-2018 IPR016047 Peptidase M23 WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 Pfam PF08525 Opacity-associated protein A N-terminal motif 12 39 2.4E-8 T 28-03-2018 IPR013731 Opacity-associated protein A, N-terminal WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 Pfam PF01476 LysM domain 98 141 5.1E-8 T 28-03-2018 IPR018392 LysM domain WM46_RS04325 ffb12557786fe0dcd55cb78dc45fa01a 440 Gene3D G3DSA:3.10.350.10 85 205 3.2E-6 T 28-03-2018 WM46_RS19715 3fc9eb04448c5e80619a55bbf7904bb1 137 Gene3D G3DSA:2.60.40.790 5 137 9.0E-21 T 28-03-2018 IPR008978 HSP20-like chaperone WM46_RS19715 3fc9eb04448c5e80619a55bbf7904bb1 137 Hamap MF_02000 Small heat shock protein IbpA [ibpA]. 1 137 49.997 T 28-03-2018 IPR023728 Small heat shock protein IbpA WM46_RS19715 3fc9eb04448c5e80619a55bbf7904bb1 137 SUPERFAMILY SSF49764 30 137 6.98E-20 T 28-03-2018 IPR008978 HSP20-like chaperone WM46_RS19715 3fc9eb04448c5e80619a55bbf7904bb1 137 Pfam PF00011 Hsp20/alpha crystallin family 42 137 1.0E-22 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 213 226 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 Gene3D G3DSA:3.30.420.40 1 216 5.4E-35 T 28-03-2018 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 Pfam PF00012 Hsp70 protein 333 420 2.2E-5 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 Pfam PF00012 Hsp70 protein 3 228 3.3E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 Gene3D G3DSA:3.30.420.40 217 429 7.2E-30 T 28-03-2018 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 SUPERFAMILY SSF53067 208 276 1.77E-31 T 28-03-2018 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 SUPERFAMILY SSF53067 328 447 1.77E-31 T 28-03-2018 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 SUPERFAMILY SSF53067 85 205 2.41E-27 T 28-03-2018 WM46_RS02750 7b8831cc3b5036b31f7701e61556d5a4 450 SUPERFAMILY SSF53067 2 44 2.41E-27 T 28-03-2018 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 Gene3D G3DSA:3.40.50.300 16 293 3.2E-5 T 28-03-2018 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 Pfam PF00196 Bacterial regulatory proteins, luxR family 835 890 1.5E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 SUPERFAMILY SSF46894 828 892 6.8E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 SMART SM00421 833 890 5.3E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 ProSitePatterns PS00622 LuxR-type HTH domain signature. 850 877 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 Hamap MF_01247 HTH-type transcriptional regulator MalT [malT]. 1 899 39.89 T 28-03-2018 IPR023768 Transcriptional regulator HTH-type, MalT WM46_RS17925 21a601e697c36b713b1b6410be809003 901 SUPERFAMILY SSF52540 6 226 2.81E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17925 21a601e697c36b713b1b6410be809003 901 Gene3D G3DSA:1.10.10.10 833 894 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17925 21a601e697c36b713b1b6410be809003 901 SUPERFAMILY SSF48452 442 803 5.26E-153 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 836 850 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 850 866 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 866 878 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS17925 21a601e697c36b713b1b6410be809003 901 Gene3D G3DSA:1.25.40.10 436 808 8.4E-45 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS11795 b6e74f4f7cf27956e72b4f0d28e714d6 412 Pfam PF03825 Nucleoside H+ symporter 21 409 1.2E-99 T 28-03-2018 WM46_RS11795 b6e74f4f7cf27956e72b4f0d28e714d6 412 SUPERFAMILY SSF103473 16 407 1.57E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS11795 b6e74f4f7cf27956e72b4f0d28e714d6 412 Gene3D G3DSA:1.20.1250.20 14 206 2.1E-10 T 28-03-2018 WM46_RS11795 b6e74f4f7cf27956e72b4f0d28e714d6 412 Gene3D G3DSA:1.20.1250.20 207 411 7.2E-21 T 28-03-2018 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 SUPERFAMILY SSF52518 7 175 6.42E-32 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 PIRSF PIRSF004983 1 556 1.3E-184 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 SUPERFAMILY SSF52518 367 552 3.93E-34 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 169 1.2E-27 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 417 534 2.8E-8 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 553 32.786 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 430 3.8E-139 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Gene3D G3DSA:3.40.50.970 357 556 2.9E-31 T 28-03-2018 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Pfam PF16582 Middle domain of thiamine pyrophosphate 184 388 6.6E-87 T 28-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Gene3D G3DSA:3.40.50.1220 216 356 3.7E-15 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS01850 a11ec8452663baa49e783e331a24c2c6 556 Gene3D G3DSA:3.40.50.970 1 204 1.9E-54 T 28-03-2018 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 Pfam PF13247 4Fe-4S dicluster domain 175 271 4.7E-37 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 Gene3D G3DSA:3.30.70.20 364 467 2.6E-30 T 28-03-2018 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 Gene3D G3DSA:3.30.70.20 237 363 8.9E-32 T 28-03-2018 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 Gene3D G3DSA:3.30.70.20 198 236 9.4E-20 T 28-03-2018 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 436 4.9E-30 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 493 6.9E-299 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 Gene3D G3DSA:3.30.70.20 5 197 2.6E-28 T 28-03-2018 WM46_RS06740 fbdacff494a6285433038c5458e484e3 514 SUPERFAMILY SSF54862 1 503 1.99E-183 T 28-03-2018 WM46_RS02845 7c85b9c40d8da1a539e7b15b59a589d7 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 233 2.4E-72 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS02845 7c85b9c40d8da1a539e7b15b59a589d7 321 SUPERFAMILY SSF51735 1 318 2.41E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02845 7c85b9c40d8da1a539e7b15b59a589d7 321 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 3 314 49.018 T 28-03-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 WM46_RS02845 7c85b9c40d8da1a539e7b15b59a589d7 321 Gene3D G3DSA:3.90.25.10 166 321 1.1E-44 T 28-03-2018 WM46_RS02845 7c85b9c40d8da1a539e7b15b59a589d7 321 Gene3D G3DSA:3.40.50.720 4 165 8.8E-13 T 28-03-2018 WM46_RS01675 ef81c0d52d099b4558751a99cf5cec9a 188 Pfam PF00293 NUDIX domain 37 153 7.3E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS01675 ef81c0d52d099b4558751a99cf5cec9a 188 SUPERFAMILY SSF55811 10 166 8.8E-36 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS01675 ef81c0d52d099b4558751a99cf5cec9a 188 PIRSF PIRSF017340 2 172 1.3E-75 T 28-03-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 WM46_RS01675 ef81c0d52d099b4558751a99cf5cec9a 188 Gene3D G3DSA:3.90.79.10 2 181 7.0E-40 T 28-03-2018 WM46_RS20225 e51cae56535d40c85c1ed102bc5b2c6a 320 Gene3D G3DSA:3.40.50.2000 1 163 1.0E-40 T 28-03-2018 WM46_RS20225 e51cae56535d40c85c1ed102bc5b2c6a 320 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 319 1.1E-130 T 28-03-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 WM46_RS20225 e51cae56535d40c85c1ed102bc5b2c6a 320 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 77 302 5.6E-76 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 WM46_RS20225 e51cae56535d40c85c1ed102bc5b2c6a 320 Gene3D G3DSA:3.40.50.2000 164 320 3.1E-32 T 28-03-2018 WM46_RS20225 e51cae56535d40c85c1ed102bc5b2c6a 320 SUPERFAMILY SSF53756 1 320 1.76E-71 T 28-03-2018 WM46_RS13455 c8a2fe4bc93ae8b333aeb7cbc9776a75 398 Gene3D G3DSA:1.10.443.10 204 385 9.9E-29 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS13455 c8a2fe4bc93ae8b333aeb7cbc9776a75 398 Pfam PF13356 Arm DNA-binding domain 3 88 3.5E-19 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS13455 c8a2fe4bc93ae8b333aeb7cbc9776a75 398 Gene3D G3DSA:1.10.150.130 89 203 1.1E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS13455 c8a2fe4bc93ae8b333aeb7cbc9776a75 398 SUPERFAMILY SSF56349 98 380 2.21E-67 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS13455 c8a2fe4bc93ae8b333aeb7cbc9776a75 398 Pfam PF00589 Phage integrase family 207 370 4.3E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS08325 bc81220709eff425a660777a810241f3 173 Gene3D G3DSA:1.20.120.450 2 150 2.3E-11 T 28-03-2018 WM46_RS08325 bc81220709eff425a660777a810241f3 173 PIRSF PIRSF031551 1 170 6.8E-59 T 28-03-2018 IPR012550 Protein of unknown function DUF1706 WM46_RS08325 bc81220709eff425a660777a810241f3 173 Pfam PF08020 Protein of unknown function (DUF1706) 1 165 3.4E-55 T 28-03-2018 IPR012550 Protein of unknown function DUF1706 WM46_RS02480 cf600eff25856558803013205516ee5f 239 Gene3D G3DSA:3.40.50.620 37 174 1.3E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS02480 cf600eff25856558803013205516ee5f 239 Pfam PF02698 DUF218 domain 48 170 2.4E-17 T 28-03-2018 IPR003848 Domain of unknown function DUF218 WM46_RS02480 cf600eff25856558803013205516ee5f 239 PIRSF PIRSF005011 1 239 8.3E-154 T 28-03-2018 IPR023604 Uncharacterised protein family SanA WM46_RS04100 cdc740dfec06011af1a7c522358e837f 142 Pfam PF00582 Universal stress protein family 3 138 6.9E-17 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS04100 cdc740dfec06011af1a7c522358e837f 142 Gene3D G3DSA:3.40.50.620 2 142 6.4E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS04100 cdc740dfec06011af1a7c522358e837f 142 PIRSF PIRSF006276 1 141 6.1E-45 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS04100 cdc740dfec06011af1a7c522358e837f 142 SUPERFAMILY SSF52402 3 139 2.34E-26 T 28-03-2018 WM46_RS02350 fd31c597c4fff3f79e71b260ab676fb1 210 Hamap MF_01150 Chaperone protein TorD [torD]. 2 196 26.333 T 28-03-2018 IPR023069 Chaperone TorD WM46_RS02350 fd31c597c4fff3f79e71b260ab676fb1 210 Gene3D G3DSA:1.10.3480.10 1 206 1.6E-32 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS02350 fd31c597c4fff3f79e71b260ab676fb1 210 Pfam PF02613 Nitrate reductase delta subunit 50 166 7.2E-19 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS02350 fd31c597c4fff3f79e71b260ab676fb1 210 SUPERFAMILY SSF89155 5 197 2.22E-34 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS07685 4c89ad15483e1ba49ab277466d4223a7 101 SUPERFAMILY SSF54909 3 97 3.97E-33 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS07685 4c89ad15483e1ba49ab277466d4223a7 101 Pfam PF08803 Putative mono-oxygenase ydhR 4 98 1.1E-39 T 28-03-2018 IPR014910 Putative monooxygenase YdhR WM46_RS08335 9a3b63133d6862a1db4a05a27fccf56a 137 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 3 129 38.685 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM46_RS08335 9a3b63133d6862a1db4a05a27fccf56a 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 4 134 4.4E-66 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM46_RS08335 9a3b63133d6862a1db4a05a27fccf56a 137 Gene3D G3DSA:2.170.150.20 1 137 1.0E-58 T 28-03-2018 WM46_RS08335 9a3b63133d6862a1db4a05a27fccf56a 137 Pfam PF01641 SelR domain 10 127 4.8E-54 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 WM46_RS08335 9a3b63133d6862a1db4a05a27fccf56a 137 SUPERFAMILY SSF51316 5 132 2.76E-59 T 28-03-2018 IPR011057 Mss4-like WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Gene3D G3DSA:3.30.565.10 383 549 2.7E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 SUPERFAMILY SSF55890 332 376 3.92E-8 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 SUPERFAMILY SSF103190 48 178 6.54E-32 T 28-03-2018 IPR029151 Periplasmic sensor domain-like WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Gene3D G3DSA:3.30.450.20 41 173 1.6E-22 T 28-03-2018 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 SUPERFAMILY SSF55874 410 541 5.63E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 483 4.5E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 538 4.5E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 519 4.5E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 497 4.5E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 SUPERFAMILY SSF55785 223 283 9.42E-9 T 28-03-2018 IPR000014 PAS domain WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Gene3D G3DSA:3.30.450.20 219 330 3.9E-9 T 28-03-2018 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Pfam PF00989 PAS fold 225 287 3.5E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Pfam PF17203 Single cache domain 3 59 173 4.0E-21 T 28-03-2018 IPR033463 Single cache domain 3 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 SMART SM00387 428 541 1.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 SMART SM00091 222 292 3.4E-8 T 28-03-2018 IPR000014 PAS domain WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Gene3D G3DSA:1.10.287.130 331 382 6.0E-14 T 28-03-2018 WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 539 3.6E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS11465 0d27c3f979c0021d005b0a496cb4ccaf 553 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 330 374 4.2E-8 T 28-03-2018 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Pfam PF01043 SecA preprotein cross-linking domain 232 358 9.2E-40 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SUPERFAMILY SSF52540 368 415 5.63E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SUPERFAMILY SSF52540 5 228 5.63E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Pfam PF07517 SecA DEAD-like domain 7 402 3.0E-131 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Gene3D G3DSA:3.10.450.50 734 901 1.5E-56 T 28-03-2018 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 817 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SUPERFAMILY SSF81886 620 840 7.19E-86 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SUPERFAMILY SSF81886 877 889 7.19E-86 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Gene3D G3DSA:3.40.50.300 417 634 7.1E-54 T 28-03-2018 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SUPERFAMILY SSF52540 416 618 1.98E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 ProSitePatterns PS01312 SecA family signature. 500 515 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Gene3D G3DSA:3.40.50.300 303 416 5.6E-8 T 28-03-2018 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Gene3D G3DSA:3.40.50.300 9 267 3.6E-56 T 28-03-2018 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Pfam PF07516 SecA Wing and Scaffold domain 617 830 4.7E-69 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Pfam PF02810 SEC-C motif 881 899 1.1E-10 T 28-03-2018 IPR004027 SEC-C motif WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Gene3D G3DSA:1.10.3060.10 635 733 4.9E-29 T 28-03-2018 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SUPERFAMILY SSF81767 227 368 1.05E-43 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.872 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SMART SM00958 228 358 2.5E-83 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 170 190 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 117 127 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 376 393 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 63 87 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 101 115 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 413 426 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 PRINTS PR00906 SecA protein signature 339 361 5.2E-74 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 WM46_RS14340 aaea8691f60b70e79128f91bfa6183e6 901 SMART SM00957 6 402 0.0 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 Pfam PF13242 HAD-hyrolase-like 109 179 2.4E-13 T 28-03-2018 WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 Gene3D G3DSA:3.40.50.1000 4 188 3.7E-33 T 28-03-2018 IPR023214 HAD-like domain WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 156 8.9E-39 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 PIRSF PIRSF004682 1 188 1.8E-67 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 6 180 1.4E-97 T 28-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 SUPERFAMILY SSF56784 3 185 1.76E-53 T 28-03-2018 IPR023214 HAD-like domain WM46_RS13815 90676b525e034a37dbb3ed63cdbb3368 188 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 6 155 8.9E-39 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 WM46_RS20885 8701e15828e7f781a4b30841093c7021 105 Pfam PF01340 Met Apo-repressor, MetJ 3 99 1.4E-58 T 28-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 WM46_RS20885 8701e15828e7f781a4b30841093c7021 105 Hamap MF_00744 Met repressor [metJ]. 1 105 41.993 T 28-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 WM46_RS20885 8701e15828e7f781a4b30841093c7021 105 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 10 101 3.0E-48 T 28-03-2018 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 WM46_RS20885 8701e15828e7f781a4b30841093c7021 105 Gene3D G3DSA:1.10.140.10 3 103 3.9E-59 T 28-03-2018 IPR023453 Methionine repressor MetJ domain WM46_RS20885 8701e15828e7f781a4b30841093c7021 105 SUPERFAMILY SSF47598 2 105 7.34E-58 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM46_RS22465 cc929c6e397c092356df73dc2c32a9d1 368 SUPERFAMILY SSF56672 67 323 2.8E-17 T 28-03-2018 WM46_RS22465 cc929c6e397c092356df73dc2c32a9d1 368 Gene3D G3DSA:3.30.70.270 5 279 1.3E-24 T 28-03-2018 WM46_RS22465 cc929c6e397c092356df73dc2c32a9d1 368 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 126 279 7.6E-20 T 28-03-2018 IPR000477 Reverse transcriptase domain WM46_RS14610 78df3cb35803ca4004e4969bade517e9 95 PIRSF PIRSF036548 1 95 2.3E-38 T 28-03-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 WM46_RS14610 78df3cb35803ca4004e4969bade517e9 95 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 37 91 9.7E-5 T 28-03-2018 WM46_RS14610 78df3cb35803ca4004e4969bade517e9 95 SUPERFAMILY SSF54862 40 90 3.14E-8 T 28-03-2018 WM46_RS14610 78df3cb35803ca4004e4969bade517e9 95 Gene3D G3DSA:3.30.70.20 39 71 4.3E-5 T 28-03-2018 WM46_RS03435 4d218d148de7b5ae1ac1bc4d80a1bac6 150 PIRSF PIRSF036409 1 146 4.3E-56 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 WM46_RS03435 4d218d148de7b5ae1ac1bc4d80a1bac6 150 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 141 3.3E-56 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 WM46_RS03435 4d218d148de7b5ae1ac1bc4d80a1bac6 150 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 142 1.1E-55 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 WM46_RS03435 4d218d148de7b5ae1ac1bc4d80a1bac6 150 Gene3D G3DSA:3.40.50.300 2 145 4.0E-13 T 28-03-2018 WM46_RS03435 4d218d148de7b5ae1ac1bc4d80a1bac6 150 SUPERFAMILY SSF52540 3 140 2.45E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19555 af9be8fa2df22904f6e093a02ffeef7f 319 Gene3D G3DSA:1.10.3720.10 12 306 4.4E-32 T 28-03-2018 WM46_RS19555 af9be8fa2df22904f6e093a02ffeef7f 319 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 16 311 1.6E-93 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 WM46_RS19555 af9be8fa2df22904f6e093a02ffeef7f 319 SUPERFAMILY SSF161098 28 303 2.8E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS19555 af9be8fa2df22904f6e093a02ffeef7f 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 304 1.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 Gene3D G3DSA:3.40.50.720 1 33 9.7E-7 T 28-03-2018 WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 Gene3D G3DSA:3.40.50.720 34 247 2.7E-60 T 28-03-2018 WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 SUPERFAMILY SSF51735 3 246 5.5E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 9.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 9.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 9.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 189 0.0034 T 28-03-2018 WM46_RS24215 358362b4351bd7b2cf261fa513d9e6ba 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 246 1.3E-55 T 28-03-2018 WM46_RS21540 358f11c0d3bda6dc4b8cbc94520b19cd 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 289 9.6E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS21540 358f11c0d3bda6dc4b8cbc94520b19cd 296 Gene3D G3DSA:1.10.3720.10 1 283 3.0E-42 T 28-03-2018 WM46_RS21540 358f11c0d3bda6dc4b8cbc94520b19cd 296 SUPERFAMILY SSF161098 8 296 1.96E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 Gene3D G3DSA:1.10.10.10 1 79 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 Gene3D G3DSA:3.40.190.10 180 263 2.2E-10 T 28-03-2018 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 Pfam PF03466 LysR substrate binding domain 87 288 1.7E-33 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 SUPERFAMILY SSF53850 89 294 1.37E-30 T 28-03-2018 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 Gene3D G3DSA:3.40.190.10 80 179 3.9E-15 T 28-03-2018 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 SUPERFAMILY SSF46785 1 86 1.67E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03680 c97c22256357c7c8f46255bd178570c9 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.3E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19890 93d13bfe6f8fe2461ff78a7950fb061e 100 PIRSF PIRSF000699 1 100 1.1E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS19890 93d13bfe6f8fe2461ff78a7950fb061e 100 SUPERFAMILY SSF46973 2 100 2.09E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS19890 93d13bfe6f8fe2461ff78a7950fb061e 100 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 99 1.7E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS19890 93d13bfe6f8fe2461ff78a7950fb061e 100 Gene3D G3DSA:1.20.58.80 3 100 1.0E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Pfam PF00270 DEAD/DEAH box helicase 602 762 1.4E-20 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Gene3D G3DSA:3.30.2060.10 130 203 4.9E-5 T 28-03-2018 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SMART SM01058 476 573 1.2E-50 T 28-03-2018 IPR003711 CarD-like/TRCF domain WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SMART SM00490 823 907 3.0E-19 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Pfam PF03461 TRCF domain 1006 1097 6.0E-28 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SUPERFAMILY SSF52540 520 780 5.41E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 31 1125 28.83 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SUPERFAMILY SSF141259 467 545 1.7E-23 T 28-03-2018 IPR003711 CarD-like/TRCF domain WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SUPERFAMILY SSF143517 992 1144 3.27E-44 T 28-03-2018 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SUPERFAMILY SSF52540 351 463 1.89E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SMART SM00487 597 787 1.7E-35 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Pfam PF02559 CarD-like/TRCF domain 477 572 4.7E-25 T 28-03-2018 IPR003711 CarD-like/TRCF domain WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Gene3D G3DSA:3.40.50.300 355 785 3.7E-43 T 28-03-2018 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Gene3D G3DSA:3.40.50.300 786 953 8.5E-26 T 28-03-2018 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 Pfam PF00271 Helicase conserved C-terminal domain 802 906 1.0E-17 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SUPERFAMILY SSF52540 6 341 1.24E-100 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SMART SM00982 1005 1105 3.4E-49 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 145 1079 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 WM46_RS08565 7c893d751da52597f0e720bdca3534e8 1148 SUPERFAMILY SSF52540 779 987 4.14E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 Gene3D G3DSA:1.10.150.130 3 100 3.2E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 298 59.028 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 Gene3D G3DSA:1.10.443.10 111 292 1.5E-50 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 4 298 65.631 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 Pfam PF00589 Phage integrase family 113 283 2.6E-56 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 SUPERFAMILY SSF47823 4 100 6.87E-35 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 90 4.8E-24 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 298 2.0E-119 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 WM46_RS24260 0fa47256b0defb2b7f548678ab2fd4ec 298 SUPERFAMILY SSF56349 106 296 1.85E-59 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 Pfam PF05343 M42 glutamyl aminopeptidase 46 346 1.8E-90 T 28-03-2018 IPR008007 Peptidase M42 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 Gene3D G3DSA:3.40.630.10 171 353 1.9E-32 T 28-03-2018 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 Gene3D G3DSA:2.40.30.40 71 163 1.1E-26 T 28-03-2018 IPR023367 Peptidase M42, domain 2 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 SUPERFAMILY SSF53187 6 82 1.14E-53 T 28-03-2018 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 SUPERFAMILY SSF53187 172 351 1.14E-53 T 28-03-2018 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 SUPERFAMILY SSF101821 72 180 1.68E-26 T 28-03-2018 WM46_RS06470 7ba53f3dcf61162242e80f983c3eeace 373 PIRSF PIRSF001123 3 356 1.1E-93 T 28-03-2018 IPR008007 Peptidase M42 WM46_RS19870 8213877e1337d7edba3b38d53d403380 107 Gene3D G3DSA:1.10.260.40 50 100 2.9E-10 T 28-03-2018 WM46_RS19870 8213877e1337d7edba3b38d53d403380 107 SUPERFAMILY SSF47413 52 106 4.29E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS19870 8213877e1337d7edba3b38d53d403380 107 Pfam PF01381 Helix-turn-helix 52 96 7.4E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.3E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 192 208 2.5E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Pfam PF14815 NUDIX domain 234 343 4.7E-25 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 SUPERFAMILY SSF55811 220 344 1.06E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Gene3D G3DSA:3.90.79.10 231 348 5.1E-11 T 28-03-2018 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 192 208 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 167 5.0E-23 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 SMART SM00478 39 190 2.6E-53 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 SUPERFAMILY SSF48150 3 225 6.6E-79 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 277 2.6E-130 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Gene3D G3DSA:1.10.340.30 21 117 6.9E-33 T 28-03-2018 WM46_RS15135 544c890d64fae52b6db8320d12f3e6b7 350 Gene3D G3DSA:1.10.1670.10 118 225 1.3E-33 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 SUPERFAMILY SSF53850 1 242 1.95E-73 T 28-03-2018 WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 Gene3D G3DSA:3.40.190.10 133 243 2.0E-21 T 28-03-2018 WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 45 58 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 241 4.0E-89 T 28-03-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0006810|GO:0030288 WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 Gene3D G3DSA:3.40.190.10 11 132 6.9E-38 T 28-03-2018 WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 SMART SM00062 22 242 4.9E-86 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 23 242 8.8E-71 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS10130 feee0cd875dd898225e820074deb5f82 243 SMART SM00079 22 243 0.0037 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 SUPERFAMILY SSF54675 12 130 1.95E-32 T 28-03-2018 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 SUPERFAMILY SSF51690 131 296 6.28E-59 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 Gene3D G3DSA:3.20.20.70 157 286 9.2E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 PIRSF PIRSF006250 17 299 1.8E-110 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 42 129 9.7E-25 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 Gene3D G3DSA:3.90.1170.20 11 156 6.8E-43 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 27 296 2.5E-102 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 WM46_RS14295 ccb58abb5ed5a688f4142147225decde 299 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 131 295 3.4E-60 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 WM46_RS15260 77e38068edf5e4fbd8b7845121b98d70 128 Gene3D G3DSA:3.10.400.10 1 128 1.2E-48 T 28-03-2018 WM46_RS15260 77e38068edf5e4fbd8b7845121b98d70 128 SUPERFAMILY SSF88697 3 126 4.72E-43 T 28-03-2018 IPR015947 PUA-like domain WM46_RS15260 77e38068edf5e4fbd8b7845121b98d70 128 Pfam PF04266 ASCH domain 19 126 2.9E-24 T 28-03-2018 IPR007374 ASCH domain WM46_RS15260 77e38068edf5e4fbd8b7845121b98d70 128 SMART SM01022 9 126 1.4E-40 T 28-03-2018 IPR007374 ASCH domain WM46_RS15260 77e38068edf5e4fbd8b7845121b98d70 128 PIRSF PIRSF021320 2 128 1.9E-43 T 28-03-2018 IPR009326 Protein of unknown function DUF984 WM46_RS05270 77e38068edf5e4fbd8b7845121b98d70 128 Gene3D G3DSA:3.10.400.10 1 128 1.2E-48 T 28-03-2018 WM46_RS05270 77e38068edf5e4fbd8b7845121b98d70 128 SUPERFAMILY SSF88697 3 126 4.72E-43 T 28-03-2018 IPR015947 PUA-like domain WM46_RS05270 77e38068edf5e4fbd8b7845121b98d70 128 Pfam PF04266 ASCH domain 19 126 2.9E-24 T 28-03-2018 IPR007374 ASCH domain WM46_RS05270 77e38068edf5e4fbd8b7845121b98d70 128 SMART SM01022 9 126 1.4E-40 T 28-03-2018 IPR007374 ASCH domain WM46_RS05270 77e38068edf5e4fbd8b7845121b98d70 128 PIRSF PIRSF021320 2 128 1.9E-43 T 28-03-2018 IPR009326 Protein of unknown function DUF984 WM46_RS21885 a4278b3d8f289645b5fd709b19348cf8 259 SUPERFAMILY SSF161098 62 253 7.46E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS21885 a4278b3d8f289645b5fd709b19348cf8 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 258 1.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS21885 a4278b3d8f289645b5fd709b19348cf8 259 Gene3D G3DSA:1.10.3720.10 12 259 7.2E-32 T 28-03-2018 WM46_RS21885 a4278b3d8f289645b5fd709b19348cf8 259 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 16 258 2.6E-93 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 WM46_RS21990 cb779bc8e92eaea0bc7a4a4e0acb5c96 446 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 376 1.7E-149 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS21990 cb779bc8e92eaea0bc7a4a4e0acb5c96 446 PIRSF PIRSF004539 1 444 7.4E-196 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS21990 cb779bc8e92eaea0bc7a4a4e0acb5c96 446 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 443 5.6E-200 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS08980 a3b8880f6890e73042e5ad3f1d6ff689 184 SUPERFAMILY SSF89155 2 180 5.36E-43 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS08980 a3b8880f6890e73042e5ad3f1d6ff689 184 PIRSF PIRSF004690 1 184 1.4E-55 T 28-03-2018 IPR026269 Tat proofreading chaperone DmsD-type WM46_RS08980 a3b8880f6890e73042e5ad3f1d6ff689 184 Gene3D G3DSA:1.10.3480.10 1 184 4.8E-36 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS08980 a3b8880f6890e73042e5ad3f1d6ff689 184 Pfam PF02613 Nitrate reductase delta subunit 36 147 2.0E-13 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS16890 746479a32d333a3b11fa55d8b17a16d5 185 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 153 7.7E-56 T 28-03-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 WM46_RS16890 746479a32d333a3b11fa55d8b17a16d5 185 Pfam PF02470 MlaD protein 39 116 5.4E-23 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 Gene3D G3DSA:3.10.105.10 348 532 1.7E-5 T 28-03-2018 WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 168 303 4.0E-14 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 Pfam PF12793 Sugar transport-related sRNA regulator N-term 6 118 1.9E-37 T 28-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 Gene3D G3DSA:3.40.190.10 262 307 5.8E-4 T 28-03-2018 WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 Gene3D G3DSA:1.10.10.10 1 143 2.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 SUPERFAMILY SSF53850 122 561 2.35E-52 T 28-03-2018 WM46_RS12590 bafa21a50aef4eade688d588aa6ea070 566 Gene3D G3DSA:3.90.76.10 144 261 1.2E-13 T 28-03-2018 WM46_RS06050 01bf7014baef4d2e16d51340f756bc0b 330 SMART SM00382 32 235 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06050 01bf7014baef4d2e16d51340f756bc0b 330 Gene3D G3DSA:3.40.50.300 1 328 3.8E-56 T 28-03-2018 WM46_RS06050 01bf7014baef4d2e16d51340f756bc0b 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 8.1E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS06050 01bf7014baef4d2e16d51340f756bc0b 330 SUPERFAMILY SSF52540 3 258 3.24E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06050 01bf7014baef4d2e16d51340f756bc0b 330 Pfam PF00005 ABC transporter 24 187 7.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS06050 01bf7014baef4d2e16d51340f756bc0b 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 2.5E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Hamap MF_01630 Nitrate reductase [napA]. 1 828 30.482 T 28-03-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Gene3D G3DSA:3.40.50.740 304 668 3.2E-66 T 28-03-2018 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Gene3D G3DSA:3.40.50.740 99 268 1.7E-35 T 28-03-2018 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 1.3E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Pfam PF01568 Molydopterin dinucleotide binding domain 714 822 1.9E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Pfam PF00384 Molybdopterin oxidoreductase 96 567 4.0E-88 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 2 828 0.0 T 28-03-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042128|GO:0042597|GO:0051539|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 92 3.5E-17 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 SUPERFAMILY SSF53706 37 700 2.75E-202 T 28-03-2018 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 44 61 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 SUPERFAMILY SSF50692 688 828 1.02E-39 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Gene3D G3DSA:2.40.40.20 669 828 3.3E-33 T 28-03-2018 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 SMART SM00926 39 93 5.4E-14 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS02140 6e80cf6100e0d29f22a38cf9119b90c1 828 Gene3D G3DSA:2.20.25.90 34 95 8.3E-15 T 28-03-2018 WM46_RS04540 69f380ef496bbe672b0a0405fc602bcc 258 Pfam PF00717 Peptidase S24-like 170 239 1.8E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS04540 69f380ef496bbe672b0a0405fc602bcc 258 Gene3D G3DSA:2.10.109.10 127 257 5.3E-15 T 28-03-2018 WM46_RS04540 69f380ef496bbe672b0a0405fc602bcc 258 Gene3D G3DSA:1.10.260.40 1 96 4.1E-8 T 28-03-2018 WM46_RS04540 69f380ef496bbe672b0a0405fc602bcc 258 SUPERFAMILY SSF51306 147 254 9.94E-15 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS24015 465d062375641e9e10fd3c02fda8475f 354 SMART SM00267 178 348 1.0E-54 T 28-03-2018 IPR000160 GGDEF domain WM46_RS24015 465d062375641e9e10fd3c02fda8475f 354 Gene3D G3DSA:3.30.70.270 182 350 7.5E-49 T 28-03-2018 WM46_RS24015 465d062375641e9e10fd3c02fda8475f 354 SUPERFAMILY SSF55073 194 347 2.55E-44 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS24015 465d062375641e9e10fd3c02fda8475f 354 Pfam PF00990 Diguanylate cyclase, GGDEF domain 190 344 2.8E-46 T 28-03-2018 IPR000160 GGDEF domain WM46_RS24015 465d062375641e9e10fd3c02fda8475f 354 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 187 347 8.4E-47 T 28-03-2018 IPR000160 GGDEF domain WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 SUPERFAMILY SSF52540 9 232 3.22E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 Pfam PF00005 ABC transporter 25 174 2.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 Pfam PF00005 ABC transporter 279 430 5.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 SMART SM00382 34 222 1.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 SMART SM00382 285 479 0.44 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 SUPERFAMILY SSF52540 268 489 7.42E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 Gene3D G3DSA:3.40.50.300 6 260 2.1E-54 T 28-03-2018 WM46_RS23150 fda294a41c6c8090607d3ab7ae8c1785 500 Gene3D G3DSA:3.40.50.300 265 491 2.9E-39 T 28-03-2018 WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 54 3.0E-10 T 28-03-2018 WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 SMART SM00877 3 79 3.1E-27 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 Gene3D G3DSA:1.10.10.10 109 166 7.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 Pfam PF16365 Ethanolamine utilization protein EutK C-terminus 112 165 1.4E-33 T 28-03-2018 IPR032298 Ethanolamine utilization protein EutK, C-terminal WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 SUPERFAMILY SSF143414 3 89 3.79E-24 T 28-03-2018 WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 Pfam PF00936 BMC domain 4 79 8.8E-22 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS01025 627e750ba42d9d5fb60dfe2be56b9246 168 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 21 40 - T 28-03-2018 IPR020808 Bacterial microcompartments protein, conserved site WM46_RS17285 71f7207ba11db00bebb3a34144f8fd5d 341 SUPERFAMILY SSF53850 27 257 1.75E-48 T 28-03-2018 WM46_RS17285 71f7207ba11db00bebb3a34144f8fd5d 341 Gene3D G3DSA:3.40.190.10 142 223 5.8E-13 T 28-03-2018 WM46_RS17285 71f7207ba11db00bebb3a34144f8fd5d 341 SMART SM00062 36 265 1.1E-57 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS17285 71f7207ba11db00bebb3a34144f8fd5d 341 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 254 3.1E-32 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS17285 71f7207ba11db00bebb3a34144f8fd5d 341 Gene3D G3DSA:3.40.190.10 26 141 4.9E-20 T 28-03-2018 WM46_RS17285 71f7207ba11db00bebb3a34144f8fd5d 341 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 3 325 33.747 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 328 6.3E-114 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 Gene3D G3DSA:3.30.1490.20 94 155 2.2E-10 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 Gene3D G3DSA:3.30.470.20 156 336 1.3E-32 T 28-03-2018 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 Pfam PF02222 ATP-grasp domain 88 254 1.0E-54 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 SUPERFAMILY SSF51246 278 353 2.83E-20 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 Gene3D G3DSA:3.40.50.20 1 69 1.1E-15 T 28-03-2018 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 SUPERFAMILY SSF56059 79 274 1.11E-57 T 28-03-2018 WM46_RS12240 5b9ff0cfd21e36c5e9ce258fdb3e9a6b 355 SUPERFAMILY SSF52440 2 76 7.63E-16 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 SUPERFAMILY SSF103473 10 435 4.05E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 Gene3D G3DSA:1.20.1250.20 13 216 5.3E-41 T 28-03-2018 WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 Pfam PF07690 Major Facilitator Superfamily 29 282 1.1E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 Gene3D G3DSA:1.20.1250.20 234 449 1.4E-25 T 28-03-2018 WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 TIGRFAM TIGR00895 2A0115: MFS transporter, aromatic acid:H+ symporter (AAHS) family 7 403 4.8E-133 T 28-03-2018 IPR004746 Major facilitator superfamily, aromatic acid:H+ symporter family GO:0005215|GO:0006810|GO:0016021 WM46_RS20510 afc4270c701ab6980fd7a3a7d6a4b723 456 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 94 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 Hamap MF_02032 2-hydroxy-3-oxopropionate reductase [garR]. 3 296 61.888 T 28-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 SUPERFAMILY SSF48179 164 293 4.76E-37 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 Gene3D G3DSA:3.40.50.720 2 173 2.9E-35 T 28-03-2018 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 Gene3D G3DSA:1.10.1040.10 174 291 8.8E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 5.1E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 283 5.5E-38 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 294 2.5E-154 T 28-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 PIRSF PIRSF000103 1 295 6.9E-95 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM46_RS16530 01003b84819d70bc01c983f589785fb9 296 SUPERFAMILY SSF51735 2 164 3.38E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 Gene3D G3DSA:1.10.3100.10 1 73 2.7E-15 T 28-03-2018 IPR027910 YdiL-like domain WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 SMART SM00530 11 66 2.8E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 Pfam PF01381 Helix-turn-helix 12 64 4.7E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 SUPERFAMILY SSF47413 3 72 1.39E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 Pfam PF07883 Cupin domain 105 171 1.7E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 SUPERFAMILY SSF51182 51 176 1.45E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS06515 4788b43504688b5ba82aea1f5440a2e4 178 Gene3D G3DSA:2.60.120.10 74 178 9.6E-11 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS03110 71f1b17a2f0e21430c73ec824d589e13 188 Gene3D G3DSA:3.10.150.10 5 108 3.1E-5 T 28-03-2018 WM46_RS25395 fa0442de4c2532c5c3d23ab8f6dab28a 608 Pfam PF00361 Proton-conducting membrane transporter 124 401 5.1E-37 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25395 fa0442de4c2532c5c3d23ab8f6dab28a 608 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 373 399 1.6E-7 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25395 fa0442de4c2532c5c3d23ab8f6dab28a 608 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 321 340 1.6E-7 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25395 fa0442de4c2532c5c3d23ab8f6dab28a 608 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 154 178 1.6E-7 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS08455 d0d27ac2926a3123352cecfc0489f2a3 176 SUPERFAMILY SSF46894 107 165 1.05E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS08455 d0d27ac2926a3123352cecfc0489f2a3 176 SMART SM00421 109 167 0.001 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08455 d0d27ac2926a3123352cecfc0489f2a3 176 Gene3D G3DSA:1.10.10.10 77 168 2.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08455 d0d27ac2926a3123352cecfc0489f2a3 176 Pfam PF00196 Bacterial regulatory proteins, luxR family 112 164 1.9E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 Gene3D G3DSA:3.30.230.10 3 164 6.9E-46 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 Gene3D G3DSA:3.30.70.890 165 283 3.3E-25 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 Pfam PF08544 GHMP kinases C terminal 214 263 2.8E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 Pfam PF00288 GHMP kinases N terminal domain 91 148 1.7E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 275 32.741 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 1 282 1.7E-116 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 SUPERFAMILY SSF55060 165 280 4.8E-36 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 PIRSF PIRSF010376 1 282 1.4E-85 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 WM46_RS05540 977406a4c9a82bd3bf83e09ad19d548a 283 SUPERFAMILY SSF54211 1 162 9.11E-50 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 Gene3D G3DSA:1.10.12.10 225 273 3.4E-13 T 28-03-2018 IPR014748 Crontonase, C-terminal WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 279 1.6E-78 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 284 55.502 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 SUPERFAMILY SSF52096 15 280 2.85E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 TIGRFAM TIGR01929 menB: naphthoate synthase 22 281 2.4E-151 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 WM46_RS01860 7a4231be1dd1ab933625e2adf5be5eaa 285 Gene3D G3DSA:3.90.226.10 7 224 3.5E-64 T 28-03-2018 WM46_RS18425 babfef8680f8a9ee83ba9b3c43e23669 81 Gene3D G3DSA:1.20.5.370 15 47 1.0E-12 T 28-03-2018 WM46_RS18425 babfef8680f8a9ee83ba9b3c43e23669 81 Gene3D G3DSA:1.20.5.370 48 81 1.5E-10 T 28-03-2018 WM46_RS18425 babfef8680f8a9ee83ba9b3c43e23669 81 Pfam PF06005 Cell division protein ZapB 3 80 5.6E-26 T 28-03-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 WM46_RS18425 babfef8680f8a9ee83ba9b3c43e23669 81 Hamap MF_01196 Cell division protein ZapB [zapB]. 3 81 18.254 T 28-03-2018 IPR009252 Cell division protein ZapB GO:0005737|GO:0043093|GO:0090529 WM46_RS18425 babfef8680f8a9ee83ba9b3c43e23669 81 SUPERFAMILY SSF47661 8 79 4.0E-5 T 28-03-2018 IPR010989 SNARE GO:0016020|GO:0016192 WM46_RS10540 a28b8b9730c153f2c8452b1467154834 150 Pfam PF02391 MoaE protein 12 121 6.0E-36 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS10540 a28b8b9730c153f2c8452b1467154834 150 SUPERFAMILY SSF54690 6 150 2.22E-54 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS10540 a28b8b9730c153f2c8452b1467154834 150 Gene3D G3DSA:3.90.1170.40 2 149 3.0E-55 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS04270 6c8b44fa228117763cbb3dfdac51656a 272 Pfam PF01904 Protein of unknown function DUF72 21 248 1.6E-50 T 28-03-2018 IPR002763 Protein of unknown function DUF72 WM46_RS04270 6c8b44fa228117763cbb3dfdac51656a 272 SUPERFAMILY SSF117396 1 252 3.92E-64 T 28-03-2018 IPR002763 Protein of unknown function DUF72 WM46_RS04270 6c8b44fa228117763cbb3dfdac51656a 272 Gene3D G3DSA:3.20.20.410 1 256 5.2E-60 T 28-03-2018 IPR002763 Protein of unknown function DUF72 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 SUPERFAMILY SSF63411 33 263 6.23E-51 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 SUPERFAMILY SSF63411 265 502 6.2E-65 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 SUPERFAMILY SSF63411 736 956 4.19E-46 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Pfam PF16187 Middle or third domain of peptidase_M16 400 675 7.3E-54 T 28-03-2018 IPR032632 Peptidase M16, middle/third domain WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Pfam PF05193 Peptidase M16 inactive domain 216 391 3.5E-20 T 28-03-2018 IPR007863 Peptidase M16, C-terminal WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Pfam PF05193 Peptidase M16 inactive domain 681 857 2.8E-13 T 28-03-2018 IPR007863 Peptidase M16, C-terminal WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Gene3D G3DSA:3.30.830.10 272 502 2.3E-58 T 28-03-2018 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Pfam PF00675 Insulinase (Peptidase family M16) 54 191 1.2E-37 T 28-03-2018 IPR011765 Peptidase M16, N-terminal WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 SUPERFAMILY SSF63411 504 729 5.76E-45 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 75 98 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Gene3D G3DSA:3.30.830.10 722 962 1.5E-42 T 28-03-2018 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Gene3D G3DSA:3.30.830.10 22 268 4.1E-71 T 28-03-2018 WM46_RS24905 ee532760ff2cccea73c22a9c98507a58 962 Gene3D G3DSA:3.30.830.10 517 721 6.4E-14 T 28-03-2018 WM46_RS13945 7ae04dc01d1b22badee44148f1a46d22 285 Pfam PF01148 Cytidylyltransferase family 4 278 1.9E-70 T 28-03-2018 WM46_RS13945 7ae04dc01d1b22badee44148f1a46d22 285 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 239 265 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 WM46_RS07240 451bf5f9679e39d42d1a6494019bbf64 300 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 25 296 6.2E-66 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 WM46_RS07240 451bf5f9679e39d42d1a6494019bbf64 300 SUPERFAMILY SSF53850 25 299 5.19E-63 T 28-03-2018 WM46_RS07240 451bf5f9679e39d42d1a6494019bbf64 300 Gene3D G3DSA:3.40.190.10 13 177 1.4E-25 T 28-03-2018 WM46_RS07240 451bf5f9679e39d42d1a6494019bbf64 300 Gene3D G3DSA:3.40.190.10 178 299 4.6E-24 T 28-03-2018 WM46_RS03870 f3e2443e5b50e8a0061c2bc91f866092 135 PIRSF PIRSF039090 1 135 2.9E-42 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 WM46_RS03870 f3e2443e5b50e8a0061c2bc91f866092 135 SUPERFAMILY SSF101116 9 127 3.27E-37 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 WM46_RS03870 f3e2443e5b50e8a0061c2bc91f866092 135 Pfam PF02561 Flagellar protein FliS 8 125 8.6E-37 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 WM46_RS03870 f3e2443e5b50e8a0061c2bc91f866092 135 Gene3D G3DSA:1.20.120.340 2 129 1.2E-40 T 28-03-2018 WM46_RS03870 f3e2443e5b50e8a0061c2bc91f866092 135 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 126 3.0E-39 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 PIRSF PIRSF006246 1 125 3.4E-52 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 71.136 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 2.3E-67 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 SUPERFAMILY SSF50692 1 121 6.3E-48 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 Gene3D G3DSA:2.40.40.20 1 117 2.3E-52 T 28-03-2018 WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 1.0E-63 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM46_RS14120 2722d1dd960cf527c50addd099d8e2db 126 Pfam PF02261 Aspartate decarboxylase 1 114 6.6E-48 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Gene3D G3DSA:3.40.50.980 145 280 4.5E-25 T 28-03-2018 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 4 448 35.618 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Pfam PF00501 AMP-binding enzyme 13 355 6.8E-51 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Gene3D G3DSA:3.30.300.30 351 455 7.5E-18 T 28-03-2018 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Gene3D G3DSA:2.30.38.10 281 350 3.0E-9 T 28-03-2018 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 SUPERFAMILY SSF56801 8 451 3.27E-93 T 28-03-2018 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 ProSitePatterns PS00455 Putative AMP-binding domain signature. 139 150 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Pfam PF13193 AMP-binding enzyme C-terminal domain 366 425 1.2E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 Gene3D G3DSA:3.40.50.980 4 144 1.6E-19 T 28-03-2018 WM46_RS01870 36d0a9902598b2135aaef8c69722345e 456 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 29 445 2.7E-116 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 WM46_RS01005 e1414ee5639ae9913e922dc1570ddd3c 467 Pfam PF06277 Ethanolamine utilisation protein EutA 5 465 1.9E-177 T 28-03-2018 IPR009377 Ethanolamine utilisation EutA WM46_RS01005 e1414ee5639ae9913e922dc1570ddd3c 467 PIRSF PIRSF012293 2 467 1.2E-206 T 28-03-2018 IPR009377 Ethanolamine utilisation EutA WM46_RS01005 e1414ee5639ae9913e922dc1570ddd3c 467 Gene3D G3DSA:3.30.420.40 2 110 0.12 T 28-03-2018 WM46_RS01005 e1414ee5639ae9913e922dc1570ddd3c 467 Gene3D G3DSA:3.30.420.150 127 328 3.6E-9 T 28-03-2018 WM46_RS01005 e1414ee5639ae9913e922dc1570ddd3c 467 SUPERFAMILY SSF53067 8 266 5.76E-9 T 28-03-2018 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 753 37.446 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 SUPERFAMILY SSF51726 391 752 1.05E-119 T 28-03-2018 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 PIRSF PIRSF000382 2 753 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 426 749 1.2E-161 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 SUPERFAMILY SSF51726 5 389 3.4E-114 T 28-03-2018 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 311 1.2E-124 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 752 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 Gene3D G3DSA:3.20.20.210 3 385 2.0E-139 T 28-03-2018 WM46_RS19035 f203bd7909cd660760292b9786c54381 753 Gene3D G3DSA:3.20.20.210 386 753 6.6E-129 T 28-03-2018 WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 SUPERFAMILY SSF52255 7 165 7.59E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 10 163 4.7E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 10 163 32.245 T 28-03-2018 IPR033747 Class I PurE WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 Gene3D G3DSA:3.40.50.7700 1 165 1.3E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 PIRSF PIRSF001338 5 166 5.5E-67 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 SMART SM01001 8 159 8.1E-103 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM46_RS12235 7eb8c211c449f3291f989d01df26b78c 169 Pfam PF00731 AIR carboxylase 9 157 2.5E-63 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 Gene3D G3DSA:3.30.70.270 246 410 1.3E-52 T 28-03-2018 WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 SMART SM00091 3 70 29.0 T 28-03-2018 IPR000014 PAS domain WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 SMART SM00091 129 198 3.7E-4 T 28-03-2018 IPR000014 PAS domain WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 249 408 1.5E-44 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 SUPERFAMILY SSF55073 258 408 6.98E-45 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 SUPERFAMILY SSF55785 148 251 5.52E-16 T 28-03-2018 IPR000014 PAS domain WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 130 249 5.0E-13 T 28-03-2018 IPR000014 PAS domain WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 Gene3D G3DSA:3.30.450.20 115 245 6.6E-15 T 28-03-2018 WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 Pfam PF08448 PAS fold 143 244 3.7E-8 T 28-03-2018 IPR013656 PAS fold-4 WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 SMART SM00267 242 410 9.3E-66 T 28-03-2018 IPR000160 GGDEF domain WM46_RS06210 81180b58f55051ca5a6adfef84855c4c 410 Pfam PF00990 Diguanylate cyclase, GGDEF domain 253 406 1.2E-45 T 28-03-2018 IPR000160 GGDEF domain WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 Gene3D G3DSA:3.90.470.20 21 113 6.1E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 103 194 1.0E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 PRINTS PR01399 Enterobactin synthetase component D signature 73 91 9.1E-20 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 PRINTS PR01399 Enterobactin synthetase component D signature 146 162 9.1E-20 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 PRINTS PR01399 Enterobactin synthetase component D signature 44 64 9.1E-20 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 SUPERFAMILY SSF56214 102 193 2.96E-11 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS11645 ca0c54c78ca155c0a758d743a3586ec7 220 Gene3D G3DSA:3.90.470.20 114 201 9.1E-5 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 Pfam PF13286 Phosphohydrolase-associated domain 477 499 1.3E-4 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 Hamap MF_00030 Deoxyguanosinetriphosphate triphosphohydrolase [dgt]. 1 504 51.456 T 28-03-2018 IPR020779 dNTP triphosphohydrolase, type 1 GO:0000287|GO:0006203|GO:0008832 KEGG: 00230+3.1.5.1 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 Pfam PF01966 HD domain 66 146 7.5E-10 T 28-03-2018 IPR006674 HD domain WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 SUPERFAMILY SSF109604 251 432 1.66E-67 T 28-03-2018 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 SUPERFAMILY SSF109604 31 134 1.66E-67 T 28-03-2018 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 SUPERFAMILY SSF109604 182 215 1.66E-67 T 28-03-2018 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 SUPERFAMILY SSF109604 483 501 1.66E-67 T 28-03-2018 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 SMART SM00471 62 282 5.0E-11 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 Gene3D G3DSA:1.10.3210.10 3 262 4.4E-54 T 28-03-2018 WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 Gene3D G3DSA:1.10.3410.10 263 390 3.5E-24 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain WM46_RS14015 a7a3c56de48453cd2d1df5c000df8a50 505 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 502 2.5E-143 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 WM46_RS24870 c7809555141c34d6ab7c148bfa9854e1 291 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 WM46_RS24870 c7809555141c34d6ab7c148bfa9854e1 291 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 280 1.2E-76 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 WM46_RS24870 c7809555141c34d6ab7c148bfa9854e1 291 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 287 4.7E-108 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 WM46_RS24870 c7809555141c34d6ab7c148bfa9854e1 291 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 285 20.162 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 WM46_RS04390 23c02e50fcb2bea309d1577b7efc27b2 218 SUPERFAMILY SSF56317 4 196 1.83E-16 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS04390 23c02e50fcb2bea309d1577b7efc27b2 218 Gene3D G3DSA:3.60.110.10 1 146 9.5E-13 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS04390 23c02e50fcb2bea309d1577b7efc27b2 218 Pfam PF00795 Carbon-nitrogen hydrolase 5 102 1.8E-10 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 WM46_RS23250 21e5f0c22ab9f6edd776dd7185318231 94 SUPERFAMILY SSF143011 1 82 1.07E-19 T 28-03-2018 IPR035095 Toxin RelE-like domain WM46_RS23250 21e5f0c22ab9f6edd776dd7185318231 94 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 83 1.8E-8 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family WM46_RS23250 21e5f0c22ab9f6edd776dd7185318231 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 83 9.0E-11 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family WM46_RS23250 21e5f0c22ab9f6edd776dd7185318231 94 Gene3D G3DSA:3.30.2310.20 1 94 2.4E-22 T 28-03-2018 WM46_RS12075 932237546e7742c092c0c9359bcf5ddb 116 SMART SM00507 53 107 2.5E-12 T 28-03-2018 IPR003615 HNH nuclease WM46_RS12075 932237546e7742c092c0c9359bcf5ddb 116 Pfam PF01844 HNH endonuclease 66 110 1.2E-15 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 WM46_RS12075 932237546e7742c092c0c9359bcf5ddb 116 Gene3D G3DSA:3.40.1800.10 44 115 1.3E-16 T 28-03-2018 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 Pfam PF12626 Polymerase A arginine-rich C-terminus 345 463 4.7E-41 T 28-03-2018 IPR025866 Polymerase A arginine-rich C-terminal domain WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 Pfam PF01743 Poly A polymerase head domain 69 200 2.7E-39 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 227 287 1.3E-19 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 SUPERFAMILY SSF81891 198 436 8.37E-50 T 28-03-2018 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 SUPERFAMILY SSF81301 41 196 3.52E-40 T 28-03-2018 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 Gene3D G3DSA:3.30.460.10 35 197 1.2E-52 T 28-03-2018 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 Gene3D G3DSA:1.10.3090.10 198 441 2.3E-43 T 28-03-2018 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 38 465 1.5E-157 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 WM46_RS14100 937ec518da2c52ea303dc39e29c39468 472 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 31 467 39.02 T 28-03-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 WM46_RS14595 4db4eed41bf6151ddf51db6bbd1f20e1 176 Pfam PF02525 Flavodoxin-like fold 2 167 2.4E-39 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS14595 4db4eed41bf6151ddf51db6bbd1f20e1 176 Gene3D G3DSA:3.40.50.360 1 176 3.6E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS14595 4db4eed41bf6151ddf51db6bbd1f20e1 176 SUPERFAMILY SSF52218 2 170 2.56E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS14595 4db4eed41bf6151ddf51db6bbd1f20e1 176 Hamap MF_01414 Glutathione-regulated potassium-efflux system ancillary protein KefF [kefF]. 1 173 53.552 T 28-03-2018 IPR023948 Glutathione-regulated potassium-efflux system ancillary protein KefF GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 WM46_RS06970 93e59ba5dea7c57bb3f98410ff43e182 140 SUPERFAMILY SSF47413 6 65 3.94E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS06970 93e59ba5dea7c57bb3f98410ff43e182 140 Gene3D G3DSA:1.10.10.60 1 29 5.8E-5 T 28-03-2018 WM46_RS06970 93e59ba5dea7c57bb3f98410ff43e182 140 Gene3D G3DSA:3.30.1190.10 30 120 1.6E-8 T 28-03-2018 WM46_RS06970 93e59ba5dea7c57bb3f98410ff43e182 140 SMART SM00530 4 63 4.0E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS06970 93e59ba5dea7c57bb3f98410ff43e182 140 Pfam PF01381 Helix-turn-helix 19 60 2.6E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS20355 0f16a3d8580520df5baf20d3032123b2 202 Gene3D G3DSA:3.40.30.10 1 85 3.3E-17 T 28-03-2018 WM46_RS20355 0f16a3d8580520df5baf20d3032123b2 202 SUPERFAMILY SSF47616 73 199 6.66E-13 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS20355 0f16a3d8580520df5baf20d3032123b2 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 71 2.4E-15 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS20355 0f16a3d8580520df5baf20d3032123b2 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 97 192 1.6E-8 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS20355 0f16a3d8580520df5baf20d3032123b2 202 Gene3D G3DSA:1.20.1050.10 86 202 2.8E-10 T 28-03-2018 WM46_RS20355 0f16a3d8580520df5baf20d3032123b2 202 SUPERFAMILY SSF52833 1 100 1.98E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 SUPERFAMILY SSF53850 89 270 7.42E-14 T 28-03-2018 WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 Hamap MF_01233 HTH-type transcriptional regulator HdfR [hdfR]. 1 275 49.988 T 28-03-2018 IPR020890 Transcription regulator HTH, HdfR GO:0003677|GO:0003700|GO:0045892 WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 Gene3D G3DSA:1.10.10.10 1 82 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 SUPERFAMILY SSF46785 2 85 7.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 Gene3D G3DSA:3.40.190.10 83 252 3.0E-10 T 28-03-2018 WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 Pfam PF03466 LysR substrate binding domain 87 270 1.5E-11 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19370 b0d8caa05e55d995df13a604eab9c5a9 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS16900 18c85c6bf63f9221a38033cf16c31ed4 270 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS16900 18c85c6bf63f9221a38033cf16c31ed4 270 Pfam PF00005 ABC transporter 25 172 8.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS16900 18c85c6bf63f9221a38033cf16c31ed4 270 Gene3D G3DSA:3.40.50.300 5 253 4.9E-61 T 28-03-2018 WM46_RS16900 18c85c6bf63f9221a38033cf16c31ed4 270 SUPERFAMILY SSF52540 8 238 3.13E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16900 18c85c6bf63f9221a38033cf16c31ed4 270 SMART SM00382 33 229 5.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PIRSF PIRSF006615 2 495 8.0E-188 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 494 3.6E-90 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 148 168 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 331 350 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 291 307 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 264 283 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 244 263 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 401 422 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 446 464 9.4E-44 T 28-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 SUPERFAMILY SSF55486 5 495 1.83E-115 T 28-03-2018 WM46_RS07290 db3c21d4e3a2eca554ff56b8067d32ba 495 Gene3D G3DSA:1.10.1370.10 47 494 1.1E-28 T 28-03-2018 WM46_RS05060 ca3900bba9de7ac99303110b9759e378 139 Pfam PF00717 Peptidase S24-like 57 119 6.0E-12 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS05060 ca3900bba9de7ac99303110b9759e378 139 Gene3D G3DSA:2.10.109.10 25 139 3.1E-24 T 28-03-2018 WM46_RS05060 ca3900bba9de7ac99303110b9759e378 139 SUPERFAMILY SSF51306 13 135 1.24E-33 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS05060 ca3900bba9de7ac99303110b9759e378 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 63 74 3.9E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS05060 ca3900bba9de7ac99303110b9759e378 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 52 62 3.9E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS05060 ca3900bba9de7ac99303110b9759e378 139 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 91 103 3.9E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Gene3D G3DSA:1.10.150.280 57 80 0.029 T 28-03-2018 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 SMART SM00278 73 92 1.3 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 SMART SM00278 108 127 0.05 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Pfam PF01330 RuvA N terminal domain 2 62 2.2E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Gene3D G3DSA:1.10.150.20 81 142 2.8E-14 T 28-03-2018 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 203 32.504 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 SUPERFAMILY SSF50249 2 63 4.23E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Gene3D G3DSA:2.40.50.140 2 56 3.4E-23 T 28-03-2018 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Pfam PF07499 RuvA, C-terminal domain 159 201 2.7E-15 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Gene3D G3DSA:1.10.8.10 157 202 1.7E-15 T 28-03-2018 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 Pfam PF14520 Helix-hairpin-helix domain 72 130 1.1E-15 T 28-03-2018 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 SUPERFAMILY SSF47781 66 137 1.43E-21 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 203 6.1E-73 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 WM46_RS04300 efc4779bbdcf58396de13d47f946343b 203 SUPERFAMILY SSF46929 157 201 7.59E-11 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 WM46_RS07600 a30a97d26b3b8be70226c59fce006653 277 Gene3D G3DSA:3.90.1720.10 140 277 6.6E-38 T 28-03-2018 WM46_RS07600 a30a97d26b3b8be70226c59fce006653 277 Pfam PF00877 NlpC/P60 family 159 269 3.9E-32 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain WM46_RS07600 a30a97d26b3b8be70226c59fce006653 277 SUPERFAMILY SSF54001 139 271 1.37E-41 T 28-03-2018 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 Gene3D G3DSA:3.90.1180.10 1 142 1.0E-62 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 Pfam PF00572 Ribosomal protein L13 15 138 3.5E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 PIRSF PIRSF002181 1 142 7.1E-51 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 5.5E-68 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.522 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 WM46_RS17050 955a7e9821201b2d8cc3d0372c239b73 142 SUPERFAMILY SSF52161 1 140 1.7E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 WM46_RS13015 5c313fb8dc9ad465a7f9d27b9a8caff7 102 Pfam PF10954 Protein of unknown function (DUF2755) 1 101 5.3E-50 T 28-03-2018 IPR020513 Uncharacterised protein family, inner membrane YaiY GO:0016021 WM46_RS13015 5c313fb8dc9ad465a7f9d27b9a8caff7 102 ProDom PD068630 MEMBRANE INNER YAIY TRANSMEMBRANE 1 102 3.0E-49 T 28-03-2018 IPR020513 Uncharacterised protein family, inner membrane YaiY GO:0016021 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 Pfam PF00255 Glutathione peroxidase 6 111 4.6E-44 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 SUPERFAMILY SSF52833 4 182 1.21E-54 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 Gene3D G3DSA:3.40.30.10 4 183 9.6E-45 T 28-03-2018 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 PRINTS PR01011 Glutathione peroxidase family signature 23 40 5.8E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 PRINTS PR01011 Glutathione peroxidase family signature 143 152 5.8E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 PRINTS PR01011 Glutathione peroxidase family signature 58 74 5.8E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 ProSitePatterns PS00460 Glutathione peroxidases active site. 25 40 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 61 68 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 Hamap MF_02061 Thioredoxin/glutathione peroxidase BtuE [btuE]. 3 183 51.47 T 28-03-2018 IPR033674 Thioredoxin/glutathione peroxidase BtuE KEGG: 00480+1.11.1.15+1.11.1.9|KEGG: 00590+1.11.1.9|MetaCyc: PWY-4081 WM46_RS07995 f26bdf84d7083e7eaeea653e703cd404 183 PIRSF PIRSF000303 1 183 2.4E-64 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 SUPERFAMILY SSF69593 36 260 1.11E-14 T 28-03-2018 WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 SUPERFAMILY SSF55729 312 463 7.68E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 Pfam PF13444 Acetyltransferase (GNAT) domain 322 422 2.5E-25 T 28-03-2018 WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 Pfam PF01553 Acyltransferase 66 191 2.8E-11 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 SMART SM00563 77 194 1.0E-7 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 Gene3D G3DSA:3.40.1130.10 20 264 1.4E-34 T 28-03-2018 WM46_RS13060 aa820311ccf6e16a4a0104bd97f4fd22 566 Gene3D G3DSA:3.40.630.30 302 480 1.4E-25 T 28-03-2018 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 394 413 2.2E-9 T 28-03-2018 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 70 92 2.2E-9 T 28-03-2018 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 2.2E-9 T 28-03-2018 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 PRINTS PR01036 Tetracycline resistance protein TetB signature 157 181 2.2E-9 T 28-03-2018 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 SUPERFAMILY SSF103473 465 487 6.8E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 SUPERFAMILY SSF103473 3 189 6.8E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 SUPERFAMILY SSF103473 242 413 6.8E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 Gene3D G3DSA:1.20.1250.20 246 495 1.7E-22 T 28-03-2018 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 Pfam PF07690 Major Facilitator Superfamily 12 403 2.7E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS06760 769346e0cf8381556a20f88aa7769bd4 495 Gene3D G3DSA:1.20.1250.20 1 196 4.4E-24 T 28-03-2018 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 Pfam PF00326 Prolyl oligopeptidase family 463 675 1.4E-66 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 SUPERFAMILY SSF53474 414 655 1.18E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 Gene3D G3DSA:3.40.50.1820 1 676 6.5E-80 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 SUPERFAMILY SSF50993 2 408 3.66E-77 T 28-03-2018 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 3 403 4.7E-109 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 550 1.6E-52 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 472 496 1.6E-52 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 500 519 1.6E-52 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 588 603 1.6E-52 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 606 628 1.6E-52 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 446 464 1.6E-52 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 WM46_RS04380 639a1d622708e1aa7881b83c54cfc4be 691 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 507 537 - T 28-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 WM46_RS16860 b54c3bb99465b6cb8afdd676f37e6ca4 323 Pfam PF00348 Polyprenyl synthetase 30 263 1.6E-76 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 WM46_RS16860 b54c3bb99465b6cb8afdd676f37e6ca4 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site WM46_RS16860 b54c3bb99465b6cb8afdd676f37e6ca4 323 SUPERFAMILY SSF48576 6 322 2.16E-100 T 28-03-2018 IPR008949 Isoprenoid synthase domain WM46_RS16860 b54c3bb99465b6cb8afdd676f37e6ca4 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site WM46_RS16860 b54c3bb99465b6cb8afdd676f37e6ca4 323 Gene3D G3DSA:1.10.600.10 1 323 2.3E-104 T 28-03-2018 IPR008949 Isoprenoid synthase domain WM46_RS23475 85410c74de920af5d05f868662dc686e 422 SUPERFAMILY SSF56349 97 386 3.83E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS23475 85410c74de920af5d05f868662dc686e 422 Gene3D G3DSA:1.10.443.10 202 394 1.6E-21 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS23475 85410c74de920af5d05f868662dc686e 422 Gene3D G3DSA:1.10.150.130 87 201 2.8E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS23475 85410c74de920af5d05f868662dc686e 422 Pfam PF13356 Arm DNA-binding domain 3 87 1.3E-20 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS23475 85410c74de920af5d05f868662dc686e 422 Pfam PF00589 Phage integrase family 206 383 5.6E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS13500 5d406da4662267582ac1729246440a75 902 SUPERFAMILY SSF53955 238 364 1.22E-16 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS13500 5d406da4662267582ac1729246440a75 902 Gene3D G3DSA:1.10.530.10 121 368 5.9E-15 T 28-03-2018 WM46_RS13500 5d406da4662267582ac1729246440a75 902 Pfam PF01464 Transglycosylase SLT domain 240 338 1.1E-8 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 103 696 1.1E-156 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 493 516 6.0E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 426 449 6.0E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 382 393 6.0E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 465 487 6.0E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 577 604 6.0E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 PRINTS PR01183 Ribonucleotide reductase large chain signature 251 270 6.0E-33 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 566 588 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 Pfam PF08343 Ribonucleotide reductase N-terminal 16 97 4.0E-27 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 99 171 3.4E-12 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 SUPERFAMILY SSF51998 175 698 1.71E-184 T 28-03-2018 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 15 714 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 Pfam PF02867 Ribonucleotide reductase, barrel domain 176 693 2.6E-138 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 Gene3D G3DSA:3.20.70.20 81 700 3.1E-156 T 28-03-2018 WM46_RS25645 fa171cb3ea33012b789f3f6cf4515eac 714 SUPERFAMILY SSF48168 15 174 7.85E-63 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 55 100 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 SUPERFAMILY SSF46689 57 109 2.2E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 SUPERFAMILY SSF55136 122 288 6.8E-50 T 28-03-2018 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 Pfam PF12833 Helix-turn-helix domain 27 105 1.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 Pfam PF06445 GyrI-like small molecule binding domain 127 288 5.8E-20 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 Gene3D G3DSA:1.10.10.60 6 59 6.2E-13 T 28-03-2018 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 Gene3D G3DSA:1.10.10.60 60 121 4.1E-12 T 28-03-2018 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 SUPERFAMILY SSF46689 6 55 1.04E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 SMART SM00871 126 288 6.7E-12 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 3.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 3.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 Gene3D G3DSA:3.20.80.10 122 289 1.1E-22 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain WM46_RS14855 93270270c802aea7bdcf8462ce6648c6 289 SMART SM00342 21 104 1.9E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS14945 1aa1ad705a7c1d75ab59034ecf3ede8d 141 SUPERFAMILY SSF117856 9 138 1.91E-32 T 28-03-2018 WM46_RS14945 1aa1ad705a7c1d75ab59034ecf3ede8d 141 Pfam PF03479 Domain of unknown function (DUF296) 13 119 3.8E-21 T 28-03-2018 IPR005175 PPC domain WM46_RS14945 1aa1ad705a7c1d75ab59034ecf3ede8d 141 Gene3D G3DSA:3.30.1330.80 11 141 8.3E-35 T 28-03-2018 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR01032 Gene IV protein signature 390 412 1.0E-9 T 28-03-2018 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR01032 Gene IV protein signature 230 253 1.0E-9 T 28-03-2018 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR01032 Gene IV protein signature 271 294 1.0E-9 T 28-03-2018 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR01032 Gene IV protein signature 337 365 1.0E-9 T 28-03-2018 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 Pfam PF00263 Bacterial type II and III secretion system protein 250 409 1.9E-45 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 355 388 - T 28-03-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 22 409 1.0E-127 T 28-03-2018 IPR013355 Type IV pilus secretin PilQ WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR00811 Bacterial general secretion pathway protein D signature 397 411 1.3E-11 T 28-03-2018 IPR001775 GspD/PilQ family WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR00811 Bacterial general secretion pathway protein D signature 246 270 1.3E-11 T 28-03-2018 IPR001775 GspD/PilQ family WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 PRINTS PR00811 Bacterial general secretion pathway protein D signature 374 392 1.3E-11 T 28-03-2018 IPR001775 GspD/PilQ family WM46_RS17790 979a843c5f4f2545cc72b39408b4c2ec 412 Pfam PF03958 Bacterial type II/III secretion system short domain 122 180 3.7E-10 T 28-03-2018 IPR005644 NolW-like WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 Gene3D G3DSA:1.10.287.950 317 513 1.5E-38 T 28-03-2018 WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 Gene3D G3DSA:1.10.287.950 125 316 6.4E-7 T 28-03-2018 WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 SUPERFAMILY SSF58104 235 510 1.83E-61 T 28-03-2018 WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 Pfam PF08447 PAS fold 31 110 5.1E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 Gene3D G3DSA:3.40.50.10600 9 124 6.6E-24 T 28-03-2018 WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 476 1.8E-45 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 SUPERFAMILY SSF55785 22 114 1.13E-21 T 28-03-2018 IPR000014 PAS domain WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 125 2.8E-10 T 28-03-2018 IPR000014 PAS domain WM46_RS06660 f04257cd78bc49534cc6d734e20c1342 513 SMART SM00283 263 510 8.9E-69 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS20130 fee14ebe0ce0ba1d0849dacb16fb8031 151 Pfam PF00692 dUTPase 16 149 4.6E-44 T 28-03-2018 IPR029054 dUTPase-like WM46_RS20130 fee14ebe0ce0ba1d0849dacb16fb8031 151 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 150 34.371 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 WM46_RS20130 fee14ebe0ce0ba1d0849dacb16fb8031 151 Gene3D G3DSA:2.70.40.10 116 150 5.5E-16 T 28-03-2018 WM46_RS20130 fee14ebe0ce0ba1d0849dacb16fb8031 151 Gene3D G3DSA:2.70.40.10 2 115 4.4E-40 T 28-03-2018 WM46_RS20130 fee14ebe0ce0ba1d0849dacb16fb8031 151 TIGRFAM TIGR00576 dut: dUTP diphosphatase 10 150 5.6E-50 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 WM46_RS20130 fee14ebe0ce0ba1d0849dacb16fb8031 151 SUPERFAMILY SSF51283 1 150 4.06E-55 T 28-03-2018 IPR029054 dUTPase-like WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 4.6E-29 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 317 2.0E-149 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 317 70.503 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 Gene3D G3DSA:3.40.47.10 3 162 1.3E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 SUPERFAMILY SSF53901 3 317 1.03E-71 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 Gene3D G3DSA:3.40.47.10 163 317 2.4E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS08690 c2080551f6e25792f4104e0a148a0c52 317 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 228 316 8.9E-37 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 SUPERFAMILY SSF53822 75 321 1.18E-35 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 Gene3D G3DSA:3.40.50.2300 177 321 3.9E-23 T 28-03-2018 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 Gene3D G3DSA:3.40.50.2300 70 176 7.6E-19 T 28-03-2018 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 SUPERFAMILY SSF47413 5 57 1.07E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 47 5.6E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 Pfam PF13377 Periplasmic binding protein-like domain 172 326 7.0E-17 T 28-03-2018 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 SMART SM00354 4 64 7.1E-4 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23115 ceeb7969bd9af9245ec6ff22a86fa5d2 351 Gene3D G3DSA:1.10.260.40 4 69 4.7E-11 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 Gene3D G3DSA:4.10.480.10 232 309 2.3E-28 T 28-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 Gene3D G3DSA:3.40.50.700 42 231 1.4E-55 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 224 303 6.3E-26 T 28-03-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 185 208 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 253 279 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 67 91 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 44 66 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 211 228 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 113 136 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 229 247 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 156 180 1.0E-68 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 SUPERFAMILY SSF56770 46 302 5.16E-84 T 28-03-2018 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 13 37 4.9E-6 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 3 365 1.5E-191 T 28-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 PIRSF PIRSF000310 2 367 1.2E-135 T 28-03-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 WM46_RS15945 7d3bba31d10e3f7cd99f2840cb64d001 372 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 59 204 1.9E-32 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01905 36a1a0cef16d88c92637d38965a8fe5c 327 Gene3D G3DSA:3.90.550.10 6 229 9.0E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS01905 36a1a0cef16d88c92637d38965a8fe5c 327 Pfam PF00535 Glycosyl transferase family 2 11 171 1.0E-32 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS01905 36a1a0cef16d88c92637d38965a8fe5c 327 Hamap MF_01164 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [arnC]. 2 325 60.956 T 28-03-2018 IPR022857 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase GO:0016780 KEGG: 00520+2.4.2.53 WM46_RS01905 36a1a0cef16d88c92637d38965a8fe5c 327 SUPERFAMILY SSF53448 9 229 8.19E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS04130 ecfa1ec06bbfb42857282a20a86ac33c 167 Gene3D G3DSA:2.40.50.180 35 99 4.7E-19 T 28-03-2018 WM46_RS04130 ecfa1ec06bbfb42857282a20a86ac33c 167 Gene3D G3DSA:2.30.30.40 100 145 2.9E-17 T 28-03-2018 WM46_RS04130 ecfa1ec06bbfb42857282a20a86ac33c 167 SMART SM00260 14 151 4.3E-47 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS04130 ecfa1ec06bbfb42857282a20a86ac33c 167 SUPERFAMILY SSF50341 16 156 3.92E-39 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS04130 ecfa1ec06bbfb42857282a20a86ac33c 167 Pfam PF01584 CheW-like domain 18 154 2.0E-36 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 WM46_RS03995 b641f4bc05b313038c877f93a950ab4e 307 Pfam PF07859 alpha/beta hydrolase fold 75 276 9.2E-47 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 WM46_RS03995 b641f4bc05b313038c877f93a950ab4e 307 SUPERFAMILY SSF53474 53 298 2.73E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS03995 b641f4bc05b313038c877f93a950ab4e 307 Gene3D G3DSA:3.40.50.1820 5 298 9.0E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS01945 bc34da225cb9244e7611e47fc828fc6f 429 Pfam PF07690 Major Facilitator Superfamily 23 381 2.8E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS01945 bc34da225cb9244e7611e47fc828fc6f 429 SUPERFAMILY SSF103473 10 416 8.37E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS01945 bc34da225cb9244e7611e47fc828fc6f 429 Gene3D G3DSA:1.20.1250.20 225 425 2.0E-19 T 28-03-2018 WM46_RS01945 bc34da225cb9244e7611e47fc828fc6f 429 Gene3D G3DSA:1.20.1250.20 5 215 9.3E-35 T 28-03-2018 WM46_RS21040 b4304523a5806e08c0dee7abf38fa09f 293 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 3 283 1.1E-135 T 28-03-2018 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961 WM46_RS21040 b4304523a5806e08c0dee7abf38fa09f 293 SUPERFAMILY SSF51658 15 276 1.01E-52 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS21040 b4304523a5806e08c0dee7abf38fa09f 293 Pfam PF01261 Xylose isomerase-like TIM barrel 23 234 1.5E-33 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS21040 b4304523a5806e08c0dee7abf38fa09f 293 Gene3D G3DSA:3.20.20.150 1 288 1.6E-50 T 28-03-2018 WM46_RS05105 441f02d91a320ad3e7aa0b57e4a1cc37 142 Gene3D G3DSA:3.40.50.620 2 142 1.6E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS05105 441f02d91a320ad3e7aa0b57e4a1cc37 142 PRINTS PR01438 Universal stress protein signature 103 115 6.6E-15 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS05105 441f02d91a320ad3e7aa0b57e4a1cc37 142 PRINTS PR01438 Universal stress protein signature 120 142 6.6E-15 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS05105 441f02d91a320ad3e7aa0b57e4a1cc37 142 PRINTS PR01438 Universal stress protein signature 2 20 6.6E-15 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS05105 441f02d91a320ad3e7aa0b57e4a1cc37 142 SUPERFAMILY SSF52402 2 142 7.87E-29 T 28-03-2018 WM46_RS05105 441f02d91a320ad3e7aa0b57e4a1cc37 142 Pfam PF00582 Universal stress protein family 1 142 3.2E-24 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS12325 fc99fc67209f62aba5d740a5b413f363 264 Pfam PF01963 TraB family 30 264 2.8E-36 T 28-03-2018 IPR002816 Pheromone shutdown, TraB WM46_RS00145 2b79572254a13a497e78879d02f8a863 96 SUPERFAMILY SSF54285 4 79 2.92E-26 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp WM46_RS00145 2b79572254a13a497e78879d02f8a863 96 Hamap MF_00460 Protein RnfH [rnfH]. 5 95 25.718 T 28-03-2018 IPR005346 RnfH protein WM46_RS00145 2b79572254a13a497e78879d02f8a863 96 Gene3D G3DSA:3.10.20.280 1 88 1.3E-33 T 28-03-2018 IPR005346 RnfH protein WM46_RS00145 2b79572254a13a497e78879d02f8a863 96 Pfam PF03658 RnfH family Ubiquitin 5 87 1.4E-34 T 28-03-2018 IPR005346 RnfH protein WM46_RS24475 87c1132e1e6a1cb5483b2de8be5bfc35 347 PIRSF PIRSF006470 8 340 3.9E-78 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 WM46_RS24475 87c1132e1e6a1cb5483b2de8be5bfc35 347 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 51 301 1.2E-59 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 WM46_RS24475 87c1132e1e6a1cb5483b2de8be5bfc35 347 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 67 324 3.7E-71 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 WM46_RS16190 d7e4f7e20f0ef2b2817ce6271ee6ff6d 68 SUPERFAMILY SSF109747 3 68 3.01E-40 T 28-03-2018 IPR015065 Surface composition regulator WM46_RS16190 d7e4f7e20f0ef2b2817ce6271ee6ff6d 68 Hamap MF_00525 Surface composition regulator [glgS]. 2 61 21.354 T 28-03-2018 IPR015065 Surface composition regulator WM46_RS16190 d7e4f7e20f0ef2b2817ce6271ee6ff6d 68 Pfam PF08971 Glycogen synthesis protein 3 68 2.9E-40 T 28-03-2018 IPR015065 Surface composition regulator WM46_RS16190 d7e4f7e20f0ef2b2817ce6271ee6ff6d 68 ProDom PD054490 GLYCOGEN GLGS SYNTHESIS BIOSYNTHESIS DEPENDENT BIOSYNTHESIS RPOS 3D-STRUCTURE 4 68 2.0E-29 T 28-03-2018 IPR015065 Surface composition regulator WM46_RS16190 d7e4f7e20f0ef2b2817ce6271ee6ff6d 68 Gene3D G3DSA:1.20.970.20 11 60 1.2E-28 T 28-03-2018 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 Gene3D G3DSA:3.40.1130.10 236 492 1.3E-34 T 28-03-2018 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 PIRSF PIRSF500064 2 806 0.0 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 13 803 33.498 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 11 799 0.0 T 28-03-2018 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166|Reactome: R-HSA-2426168|Reactome: R-HSA-75109 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 SUPERFAMILY SSF69593 246 487 1.22E-23 T 28-03-2018 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 SMART SM00563 300 427 7.8E-28 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 PIRSF PIRSF000437 19 806 0.0 T 28-03-2018 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|Reactome: R-HSA-1483166 WM46_RS21585 501d6ec8368f2c1a27ff9d654d885162 806 Pfam PF01553 Acyltransferase 282 424 3.9E-26 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS22405 7ecf0179de52b29b82ec04fe450d81fb 108 Pfam PF00892 EamA-like transporter family 6 104 1.6E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS22405 7ecf0179de52b29b82ec04fe450d81fb 108 SUPERFAMILY SSF103481 7 104 1.7E-13 T 28-03-2018 WM46_RS00700 ff5a1b14c31b4b0a014888f3119eea0e 330 Gene3D G3DSA:1.10.260.40 2 96 1.1E-13 T 28-03-2018 WM46_RS00700 ff5a1b14c31b4b0a014888f3119eea0e 330 Hamap MF_02017 Cytoskeleton protein RodZ [rodZ]. 1 325 44.17 T 28-03-2018 IPR023690 Cytoskeleton protein RodZ GO:0008360|GO:0016021 WM46_RS00700 ff5a1b14c31b4b0a014888f3119eea0e 330 SUPERFAMILY SSF47413 14 80 2.95E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS00700 ff5a1b14c31b4b0a014888f3119eea0e 330 Pfam PF13464 Domain of unknown function (DUF4115) 248 322 2.5E-23 T 28-03-2018 IPR025194 Domain of unknown function DUF4115 WM46_RS00700 ff5a1b14c31b4b0a014888f3119eea0e 330 Pfam PF13413 Helix-turn-helix domain 18 78 6.3E-15 T 28-03-2018 WM46_RS00700 ff5a1b14c31b4b0a014888f3119eea0e 330 SMART SM00530 18 79 9.0E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS09035 18f2c6802cb5c793a19fa303a8c980a6 138 SUPERFAMILY SSF160719 35 128 1.14E-15 T 28-03-2018 WM46_RS09035 18f2c6802cb5c793a19fa303a8c980a6 138 Gene3D G3DSA:3.10.450.40 7 134 7.3E-18 T 28-03-2018 WM46_RS09035 18f2c6802cb5c793a19fa303a8c980a6 138 Pfam PF04965 Gene 25-like lysozyme 33 114 1.7E-13 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD WM46_RS09035 18f2c6802cb5c793a19fa303a8c980a6 138 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 10 137 4.7E-31 T 28-03-2018 IPR017737 Type VI secretion system, lysozyme-related protein WM46_RS09210 4fe300c33c4b87d08a7a40084b54aa24 646 Pfam PF03239 Iron permease FTR1 family 158 555 2.8E-62 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 WM46_RS21210 9c41522c8a52473463121c175a884327 491 Gene3D G3DSA:3.30.70.270 318 490 4.2E-43 T 28-03-2018 WM46_RS21210 9c41522c8a52473463121c175a884327 491 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 333 489 6.5E-34 T 28-03-2018 IPR000160 GGDEF domain WM46_RS21210 9c41522c8a52473463121c175a884327 491 Gene3D G3DSA:3.30.450.20 156 264 2.5E-14 T 28-03-2018 WM46_RS21210 9c41522c8a52473463121c175a884327 491 Gene3D G3DSA:3.30.450.20 38 155 8.8E-13 T 28-03-2018 WM46_RS21210 9c41522c8a52473463121c175a884327 491 Pfam PF02743 Cache domain 37 251 9.4E-22 T 28-03-2018 IPR033479 Double Cache domain 1 WM46_RS21210 9c41522c8a52473463121c175a884327 491 Pfam PF00990 Diguanylate cyclase, GGDEF domain 335 485 2.6E-33 T 28-03-2018 IPR000160 GGDEF domain WM46_RS21210 9c41522c8a52473463121c175a884327 491 SUPERFAMILY SSF55073 340 489 4.63E-35 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS21210 9c41522c8a52473463121c175a884327 491 SMART SM00267 322 489 8.3E-36 T 28-03-2018 IPR000160 GGDEF domain WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 SUPERFAMILY SSF52540 12 236 5.73E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 Gene3D G3DSA:3.40.50.300 263 503 3.5E-33 T 28-03-2018 WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 SUPERFAMILY SSF52540 253 487 1.74E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 SMART SM00382 288 483 0.66 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 SMART SM00382 38 233 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 Gene3D G3DSA:3.40.50.300 2 240 1.9E-51 T 28-03-2018 WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 Pfam PF00005 ABC transporter 280 434 4.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS02465 7dc9ea8305731a294ea645923696f9a4 506 Pfam PF00005 ABC transporter 29 178 6.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS05870 3d99ae51aa026375b3bc34f47bf5e19f 196 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 28 196 1.5E-59 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS05870 3d99ae51aa026375b3bc34f47bf5e19f 196 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 24 196 2.9E-81 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS05870 3d99ae51aa026375b3bc34f47bf5e19f 196 SUPERFAMILY SSF52540 7 196 4.25E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05870 3d99ae51aa026375b3bc34f47bf5e19f 196 PIRSF PIRSF015617 1 196 2.0E-70 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 WM46_RS05870 3d99ae51aa026375b3bc34f47bf5e19f 196 Gene3D G3DSA:3.40.50.300 6 196 3.1E-72 T 28-03-2018 WM46_RS02425 28902c6279fbeff1b9e1a27a689b91e4 661 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 151 1.4E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS02425 28902c6279fbeff1b9e1a27a689b91e4 661 Gene3D G3DSA:2.40.170.20 164 661 8.1E-78 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS02425 28902c6279fbeff1b9e1a27a689b91e4 661 Gene3D G3DSA:2.170.130.10 22 158 5.5E-37 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS02425 28902c6279fbeff1b9e1a27a689b91e4 661 Pfam PF00593 TonB dependent receptor 229 660 3.9E-58 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS02425 28902c6279fbeff1b9e1a27a689b91e4 661 SUPERFAMILY SSF56935 26 661 5.7E-127 T 28-03-2018 WM46_RS02425 28902c6279fbeff1b9e1a27a689b91e4 661 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 35 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS12740 f6ab35b4cc3749bccb399de1102c667b 299 Pfam PF00348 Polyprenyl synthetase 34 269 3.1E-56 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 WM46_RS12740 f6ab35b4cc3749bccb399de1102c667b 299 SUPERFAMILY SSF48576 1 278 6.56E-88 T 28-03-2018 IPR008949 Isoprenoid synthase domain WM46_RS12740 f6ab35b4cc3749bccb399de1102c667b 299 Gene3D G3DSA:1.10.600.10 265 299 1.6E-4 T 28-03-2018 IPR008949 Isoprenoid synthase domain WM46_RS12740 f6ab35b4cc3749bccb399de1102c667b 299 Gene3D G3DSA:1.10.600.10 1 264 1.4E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain WM46_RS12740 f6ab35b4cc3749bccb399de1102c667b 299 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site WM46_RS12740 f6ab35b4cc3749bccb399de1102c667b 299 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site WM46_RS11655 715665044f5be433ee0121ef9ff2296d 202 Pfam PF10054 Predicted periplasmic lipoprotein (DUF2291) 14 188 5.1E-28 T 28-03-2018 IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein WM46_RS11655 715665044f5be433ee0121ef9ff2296d 202 PIRSF PIRSF033535 1 200 2.1E-32 T 28-03-2018 IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein WM46_RS11655 715665044f5be433ee0121ef9ff2296d 202 SUPERFAMILY SSF141318 48 198 9.15E-24 T 28-03-2018 IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein WM46_RS23805 4422729afbc2f83b1ae84fa1116c83eb 396 PIRSF PIRSF001434 1 396 9.3E-114 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS23805 4422729afbc2f83b1ae84fa1116c83eb 396 SUPERFAMILY SSF53383 26 394 2.94E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS23805 4422729afbc2f83b1ae84fa1116c83eb 396 Gene3D G3DSA:3.90.1150.10 260 396 1.9E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS23805 4422729afbc2f83b1ae84fa1116c83eb 396 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 392 1.2E-110 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 WM46_RS23805 4422729afbc2f83b1ae84fa1116c83eb 396 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 9 395 1.4E-172 T 28-03-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 WM46_RS23805 4422729afbc2f83b1ae84fa1116c83eb 396 Gene3D G3DSA:3.40.640.10 2 259 1.7E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS20235 22d918db902560f355f63785e250ec6a 310 SUPERFAMILY SSF51735 1 306 3.31E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20235 22d918db902560f355f63785e250ec6a 310 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 308 2.4E-137 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 WM46_RS20235 22d918db902560f355f63785e250ec6a 310 Gene3D G3DSA:3.90.25.10 183 310 5.4E-19 T 28-03-2018 WM46_RS20235 22d918db902560f355f63785e250ec6a 310 Gene3D G3DSA:3.40.50.720 1 182 5.6E-22 T 28-03-2018 WM46_RS20235 22d918db902560f355f63785e250ec6a 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 236 6.6E-46 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS20235 22d918db902560f355f63785e250ec6a 310 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 309 49.888 T 28-03-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 SMART SM00448 4 120 3.8E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.0E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 SUPERFAMILY SSF46894 146 207 2.38E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 1.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 SUPERFAMILY SSF52172 3 135 5.27E-21 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 Gene3D G3DSA:3.40.50.2300 3 131 3.2E-21 T 28-03-2018 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 Hamap MF_00981 Transcriptional regulatory protein RcsB [rcsB]. 1 214 51.521 T 28-03-2018 IPR030864 Transcriptional regulatory protein RcsB GO:0000160|GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 SMART SM00421 148 205 4.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 Pfam PF00072 Response regulator receiver domain 6 120 1.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02075 a4d0d02728a620eaca1f24bb25ab0c46 216 Gene3D G3DSA:1.10.10.10 132 215 2.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 Gene3D G3DSA:3.20.20.70 2 318 7.7E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 Gene3D G3DSA:3.30.70.20 319 410 1.3E-13 T 28-03-2018 WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 Pfam PF14697 4Fe-4S dicluster domain 338 394 3.2E-16 T 28-03-2018 WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 Pfam PF01180 Dihydroorotate dehydrogenase 6 304 2.1E-33 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 SUPERFAMILY SSF54862 310 399 9.34E-21 T 28-03-2018 WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 319 3.4E-59 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 378 389 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS01445 84917a0e523b7fd8d0de764d3b88b09f 411 SUPERFAMILY SSF51395 4 319 4.33E-68 T 28-03-2018 WM46_RS09440 8916923626216104d88aa6165e7c74cf 468 Pfam PF02378 Phosphotransferase system, EIIC 135 402 1.3E-17 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS09440 8916923626216104d88aa6165e7c74cf 468 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 122 458 8.8E-116 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 WM46_RS09440 8916923626216104d88aa6165e7c74cf 468 Gene3D G3DSA:3.40.50.2300 2 99 4.1E-31 T 28-03-2018 WM46_RS09440 8916923626216104d88aa6165e7c74cf 468 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 86 4.5E-27 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 WM46_RS09440 8916923626216104d88aa6165e7c74cf 468 SUPERFAMILY SSF52794 2 99 4.36E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS09440 8916923626216104d88aa6165e7c74cf 468 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 94 1.0E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS11170 c56742e371e52b22f1becbd2dd225dc8 148 SUPERFAMILY SSF46785 6 134 2.06E-45 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11170 c56742e371e52b22f1becbd2dd225dc8 148 Gene3D G3DSA:1.10.10.10 4 88 7.0E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11170 c56742e371e52b22f1becbd2dd225dc8 148 Pfam PF01475 Ferric uptake regulator family 10 130 8.9E-49 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 Gene3D G3DSA:1.25.40.10 20 294 9.1E-50 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 Pfam PF13181 Tetratricopeptide repeat 62 94 0.033 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 SUPERFAMILY SSF48452 27 283 7.59E-78 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 SMART SM00028 96 129 2.0E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 SMART SM00028 62 95 0.0033 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 SMART SM00028 234 267 15.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 Pfam PF07719 Tetratricopeptide repeat 96 129 5.3E-5 T 28-03-2018 IPR013105 Tetratricopeptide repeat 2 WM46_RS16740 fcc6ffb1ac7bbacda2a0a75fadf517c8 294 PIRSF PIRSF004654 1 292 5.0E-121 T 28-03-2018 IPR023605 Lipoprotein NlpI WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 TIGRFAM TIGR00397 mauM_napG: MauM/NapG family ferredoxin-type protein 10 216 4.3E-70 T 28-03-2018 IPR004494 MauM/NapG ferredoxin-type protein WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Gene3D G3DSA:3.30.70.20 189 225 0.0087 T 28-03-2018 WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 SUPERFAMILY SSF54862 59 204 1.05E-24 T 28-03-2018 WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Pfam PF12838 4Fe-4S dicluster domain 60 115 2.1E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Gene3D G3DSA:3.30.70.20 158 188 3.0E-7 T 28-03-2018 WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Gene3D G3DSA:3.30.70.20 30 69 4.7E-6 T 28-03-2018 WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Gene3D G3DSA:3.30.70.20 117 157 1.3E-8 T 28-03-2018 WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Pfam PF12800 4Fe-4S binding domain 136 155 0.038 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Pfam PF12800 4Fe-4S binding domain 183 196 0.2 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02145 17ebda027f24ecc061d4a3556c234135 231 Gene3D G3DSA:3.30.70.20 70 116 1.5E-10 T 28-03-2018 WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 PIRSF PIRSF000386 1 253 1.7E-103 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 255 119.55 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 234 1.7E-110 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 Gene3D G3DSA:1.10.1270.20 170 254 5.3E-36 T 28-03-2018 WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 Gene3D G3DSA:3.40.1280.10 1 169 1.9E-73 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 1.2E-71 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 WM46_RS00195 4d08d9250a437ba023b79afe4fd57c0c 255 SUPERFAMILY SSF75217 2 247 1.64E-102 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS15590 40a4a0e8b3e697d184b9531e23c80ba6 254 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 10 220 4.1E-73 T 28-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 WM46_RS15590 40a4a0e8b3e697d184b9531e23c80ba6 254 Pfam PF08900 Domain of unknown function (DUF1845) 8 219 5.8E-70 T 28-03-2018 IPR014996 Integrating conjugative element protein, PFL4669 WM46_RS22325 3f0ff87d31979de6c29bb5edc7d9f943 277 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 20 258 3.7E-23 T 28-03-2018 IPR006380 Sucrose-phosphatase-like, N-terminal WM46_RS22325 3f0ff87d31979de6c29bb5edc7d9f943 277 Gene3D G3DSA:3.30.70.1410 121 200 5.6E-24 T 28-03-2018 WM46_RS22325 3f0ff87d31979de6c29bb5edc7d9f943 277 SUPERFAMILY SSF56784 21 275 5.73E-22 T 28-03-2018 IPR023214 HAD-like domain WM46_RS22325 3f0ff87d31979de6c29bb5edc7d9f943 277 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 175 243 3.6E-12 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS00875 7d4a017ab7672bfcf279d41187938bcb 232 Pfam PF02230 Phospholipase/Carboxylesterase 4 208 4.3E-52 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 WM46_RS00875 7d4a017ab7672bfcf279d41187938bcb 232 Gene3D G3DSA:3.40.50.1820 3 208 6.5E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS00875 7d4a017ab7672bfcf279d41187938bcb 232 SUPERFAMILY SSF53474 5 206 8.24E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00458 Haem peroxidase superfamily signature 259 274 3.4E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00458 Haem peroxidase superfamily signature 318 333 3.4E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00458 Haem peroxidase superfamily signature 157 174 3.4E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00458 Haem peroxidase superfamily signature 175 187 3.4E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00458 Haem peroxidase superfamily signature 97 111 3.4E-19 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 SUPERFAMILY SSF48113 29 429 2.8E-140 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 18 725 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Gene3D G3DSA:1.10.520.10 63 216 1.2E-34 T 28-03-2018 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 479 505 3.1E-51 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 74 99 3.1E-51 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 59 72 3.1E-51 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 267 290 3.1E-51 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 33 55 3.1E-51 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 259 269 - T 28-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Gene3D G3DSA:1.10.520.10 441 589 4.3E-29 T 28-03-2018 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Gene3D G3DSA:1.10.420.10 231 397 8.1E-39 T 28-03-2018 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Gene3D G3DSA:1.10.420.10 590 701 1.7E-36 T 28-03-2018 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 SUPERFAMILY SSF48113 435 725 8.84E-103 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 ProSitePatterns PS00436 Peroxidases active site signature. 97 108 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Pfam PF00141 Peroxidase 91 396 1.1E-47 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Pfam PF00141 Peroxidase 403 699 1.7E-35 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 WM46_RS20920 a95102de33c5606ad8a89e6731236bec 726 Hamap MF_01961 Catalase-peroxidase [katG]. 11 726 39.46 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 WM46_RS04905 d055ff9c16a4f0ecf19d61dcad0d4e51 47 Hamap MF_01596 PhoP/PhoQ regulator MgrB [mgrB]. 1 47 20.73 T 28-03-2018 IPR020907 PhoP/PhoQ regulator MgrB WM46_RS04905 d055ff9c16a4f0ecf19d61dcad0d4e51 47 Pfam PF13998 MgrB protein 19 47 8.2E-18 T 28-03-2018 IPR020907 PhoP/PhoQ regulator MgrB WM46_RS20310 71d40cc98c4037f12068269ff29b0b0c 551 Pfam PF02652 L-lactate permease 16 542 1.1E-230 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 WM46_RS20310 71d40cc98c4037f12068269ff29b0b0c 551 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 544 2.5E-237 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 WM46_RS21205 637aeb55e52c2f1a7cad3a4325471d12 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 95 8.5E-26 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS21205 637aeb55e52c2f1a7cad3a4325471d12 102 Gene3D G3DSA:3.40.50.2300 2 102 9.7E-40 T 28-03-2018 WM46_RS21205 637aeb55e52c2f1a7cad3a4325471d12 102 SUPERFAMILY SSF52794 1 101 4.97E-36 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS23950 c21c0e4bb73b43506223aad957240461 763 Gene3D G3DSA:3.40.720.10 151 449 1.2E-30 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS23950 c21c0e4bb73b43506223aad957240461 763 SUPERFAMILY SSF53649 161 471 1.68E-31 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS23950 c21c0e4bb73b43506223aad957240461 763 Pfam PF00884 Sulfatase 163 446 1.0E-21 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS23950 c21c0e4bb73b43506223aad957240461 763 Hamap MF_01070 Phosphoglycerol transferase I [mdoB]. 6 738 54.995 T 28-03-2018 IPR020881 Phosphoglycerol transferase I GO:0005886|GO:0008960|GO:0009250 KEGG: 00561+2.7.8.20 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 Pfam PF00202 Aminotransferase class-III 17 420 3.7E-145 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 420 7.8E-161 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 Gene3D G3DSA:3.40.640.10 174 306 5.1E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 PIRSF PIRSF000521 123 424 1.3E-44 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 PIRSF PIRSF000521 27 131 0.0045 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 SUPERFAMILY SSF53383 20 423 8.34E-136 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 Gene3D G3DSA:3.90.1150.10 307 427 9.5E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS25720 145aa41c03d78665f99ebace79c32164 427 Gene3D G3DSA:3.90.1150.10 1 156 4.4E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 SMART SM00354 1 71 5.0E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.3E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 SUPERFAMILY SSF47413 2 59 1.59E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 SUPERFAMILY SSF53822 59 296 9.16E-18 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 Gene3D G3DSA:3.40.50.2300 165 299 1.9E-13 T 28-03-2018 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 Pfam PF13377 Periplasmic binding protein-like domain 162 293 1.2E-8 T 28-03-2018 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 Gene3D G3DSA:1.10.260.40 2 53 2.0E-20 T 28-03-2018 WM46_RS19910 9284404cf9ccb51787263a39ae9f3a38 318 Gene3D G3DSA:3.40.50.2300 54 164 4.3E-10 T 28-03-2018 WM46_RS05810 aa5cd71ae5837681bbc26a6abd9b7ca4 247 Pfam PF06790 Uncharacterised protein family (UPF0259) 1 244 3.1E-97 T 28-03-2018 IPR009627 Uncharacterised protein family UPF0259 WM46_RS05810 aa5cd71ae5837681bbc26a6abd9b7ca4 247 Hamap MF_01067 UPF0259 membrane protein YciC [yciC]. 1 246 21.997 T 28-03-2018 IPR009627 Uncharacterised protein family UPF0259 WM46_RS07910 8a509a7092573b7e89b6bc34971bcb2f 252 Gene3D G3DSA:3.20.20.70 1 252 1.2E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS07910 8a509a7092573b7e89b6bc34971bcb2f 252 ProSitePatterns PS01028 Dehydroquinase class I active site. 114 144 - T 28-03-2018 IPR018508 3-dehydroquinate dehydratase, active site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS07910 8a509a7092573b7e89b6bc34971bcb2f 252 Pfam PF01487 Type I 3-dehydroquinase 20 246 7.1E-72 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS07910 8a509a7092573b7e89b6bc34971bcb2f 252 SUPERFAMILY SSF51569 1 251 1.81E-83 T 28-03-2018 WM46_RS07910 8a509a7092573b7e89b6bc34971bcb2f 252 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 17 245 3.5E-83 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS07910 8a509a7092573b7e89b6bc34971bcb2f 252 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 17 249 42.391 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS22670 8248d52c72ed6733c3047cfd5aa31768 319 Pfam PF00589 Phage integrase family 153 304 1.1E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS22670 8248d52c72ed6733c3047cfd5aa31768 319 Gene3D G3DSA:1.10.150.130 1 110 3.0E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS22670 8248d52c72ed6733c3047cfd5aa31768 319 SUPERFAMILY SSF56349 5 312 1.15E-42 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS22670 8248d52c72ed6733c3047cfd5aa31768 319 Gene3D G3DSA:1.10.443.10 111 318 2.0E-28 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS22670 8248d52c72ed6733c3047cfd5aa31768 319 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 17 87 1.7E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS13340 d0424f047d4b0823da69e92779b1ca8c 254 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 245 1.6E-117 T 28-03-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 WM46_RS13340 d0424f047d4b0823da69e92779b1ca8c 254 Gene3D G3DSA:3.90.850.10 30 253 1.3E-70 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13340 d0424f047d4b0823da69e92779b1ca8c 254 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 47 243 5.4E-58 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13340 d0424f047d4b0823da69e92779b1ca8c 254 Gene3D G3DSA:2.30.30.370 1 29 2.6E-15 T 28-03-2018 WM46_RS13340 d0424f047d4b0823da69e92779b1ca8c 254 SUPERFAMILY SSF56529 39 246 9.42E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 Gene3D G3DSA:3.20.20.140 63 277 5.2E-50 T 28-03-2018 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 Gene3D G3DSA:3.20.20.140 278 422 1.9E-41 T 28-03-2018 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 Gene3D G3DSA:2.30.40.10 1 62 2.6E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 SUPERFAMILY SSF51556 54 381 4.61E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 SUPERFAMILY SSF51338 350 456 7.83E-36 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 Pfam PF01979 Amidohydrolase family 50 434 2.4E-20 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 SUPERFAMILY SSF51338 1 64 1.2E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24350 d194352325a8a19f51f55553e51efe81 468 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 3 453 3.0E-193 T 28-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 WM46_RS04770 18f792691f36628655e85a04c3e2703e 243 Gene3D G3DSA:3.40.140.10 1 98 7.0E-11 T 28-03-2018 WM46_RS04770 18f792691f36628655e85a04c3e2703e 243 SUPERFAMILY SSF102712 1 103 3.79E-15 T 28-03-2018 WM46_RS04770 18f792691f36628655e85a04c3e2703e 243 Pfam PF14464 Prokaryotic homologs of the JAB domain 4 101 9.8E-16 T 28-03-2018 IPR028090 JAB domain, prokaryotic WM46_RS04770 18f792691f36628655e85a04c3e2703e 243 SUPERFAMILY SSF54001 114 233 1.96E-11 T 28-03-2018 WM46_RS04770 18f792691f36628655e85a04c3e2703e 243 Gene3D G3DSA:3.90.1720.10 99 242 7.2E-11 T 28-03-2018 WM46_RS04770 18f792691f36628655e85a04c3e2703e 243 Pfam PF00877 NlpC/P60 family 117 229 1.8E-11 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain WM46_RS21615 27c0a84ed4ea6c0b580f7dfd2ae3d228 380 Pfam PF13729 F plasmid transfer operon, TraF, protein 16 298 6.9E-79 T 28-03-2018 IPR032811 Putative conjugal transfer protein TraF-related WM46_RS21615 27c0a84ed4ea6c0b580f7dfd2ae3d228 380 Gene3D G3DSA:2.40.160.60 1 375 2.7E-34 T 28-03-2018 WM46_RS21615 27c0a84ed4ea6c0b580f7dfd2ae3d228 380 SUPERFAMILY SSF56925 212 350 2.2E-5 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Gene3D G3DSA:3.40.50.80 255 396 1.5E-23 T 28-03-2018 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 SUPERFAMILY SSF63380 148 253 1.55E-28 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Hamap MF_01252 Flavohemoprotein [hmp]. 1 396 56.613 T 28-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 SUPERFAMILY SSF52343 257 394 1.57E-36 T 28-03-2018 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Gene3D G3DSA:1.10.490.10 1 157 8.4E-39 T 28-03-2018 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Pfam PF00970 Oxidoreductase FAD-binding domain 157 252 1.8E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Pfam PF00042 Globin 7 102 2.3E-14 T 28-03-2018 IPR000971 Globin GO:0020037 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 SUPERFAMILY SSF46458 1 142 2.0E-37 T 28-03-2018 IPR009050 Globin-like WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Pfam PF00175 Oxidoreductase NAD-binding domain 264 372 4.8E-17 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 263 282 4.7E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 4.7E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 256 4.7E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 PRINTS PR00410 Phenol hydroxylase reductase family signature 358 366 4.7E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00500 3765e4988bd2569f73a476c9ced30f6e 396 Gene3D G3DSA:2.40.30.10 158 254 3.4E-25 T 28-03-2018 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 Gene3D G3DSA:3.30.870.10 278 478 2.5E-26 T 28-03-2018 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 SUPERFAMILY SSF56024 29 208 3.14E-38 T 28-03-2018 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 Pfam PF13091 PLD-like domain 294 437 5.5E-26 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 Pfam PF13091 PLD-like domain 60 204 2.6E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 Hamap MF_01918 Cardiolipin synthase C [clsC]. 60 493 76.591 T 28-03-2018 IPR030871 Cardiolipin synthase C GO:0032049|GO:0090483 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 SMART SM00155 384 411 5.3E-5 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 SMART SM00155 145 172 0.19 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 SUPERFAMILY SSF56024 231 457 3.81E-35 T 28-03-2018 WM46_RS08925 814ee809bb3bdd0f631d4f6809602d63 493 Gene3D G3DSA:3.30.870.10 28 218 8.7E-27 T 28-03-2018 WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 Gene3D G3DSA:3.30.300.20 6 120 5.4E-36 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 120 23.321 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 Pfam PF02033 Ribosome-binding factor A 7 112 3.9E-33 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 119 3.3E-45 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 9.0E-47 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 WM46_RS16760 5d1c2ef840e4265879eb99e63ab1c566 133 SUPERFAMILY SSF89919 2 107 5.49E-36 T 28-03-2018 IPR023799 Ribosome-binding factor A domain WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 Pfam PF01144 Coenzyme A transferase 16 252 6.4E-54 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 SMART SM00882 15 253 2.2E-47 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 SUPERFAMILY SSF100950 284 524 4.89E-68 T 28-03-2018 WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 Gene3D G3DSA:3.40.1080.10 2 276 3.2E-64 T 28-03-2018 WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 PIRSF PIRSF000858 10 530 5.0E-206 T 28-03-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 Gene3D G3DSA:3.40.1080.10 283 531 3.3E-54 T 28-03-2018 WM46_RS07915 2f679f8b547afe2d233ad3a8f60f5131 531 SUPERFAMILY SSF100950 15 264 1.12E-78 T 28-03-2018 WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 SUPERFAMILY SSF46785 7 79 2.46E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 Gene3D G3DSA:3.30.450.40 85 255 9.5E-51 T 28-03-2018 IPR029016 GAF domain-like WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 Gene3D G3DSA:1.10.10.10 2 84 6.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 SUPERFAMILY SSF55781 77 251 1.57E-48 T 28-03-2018 IPR029016 GAF domain-like WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 Pfam PF01614 Bacterial transcriptional regulator 122 247 4.6E-40 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 Pfam PF09339 IclR helix-turn-helix domain 9 58 5.1E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS01935 609c93741c09432da0027b1f68ca6c07 260 SMART SM00346 7 95 1.3E-33 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 3.4E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 SUPERFAMILY SSF53850 100 289 1.19E-15 T 28-03-2018 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 SUPERFAMILY SSF46785 9 94 2.34E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 Gene3D G3DSA:3.40.190.10 182 274 2.2E-11 T 28-03-2018 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 Gene3D G3DSA:1.10.10.10 2 94 3.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 Gene3D G3DSA:3.40.190.10 98 181 2.3E-8 T 28-03-2018 WM46_RS20905 abbb317b22225de4c977ea0e34f81201 301 Pfam PF03466 LysR substrate binding domain 100 290 1.3E-14 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 TIGRFAM TIGR03149 cyt_nit_nrfC: cytochrome c nitrite reductase, Fe-S protein 2 222 1.2E-123 T 28-03-2018 IPR017567 Cytochrome c nitrite reductase, Fe-S protein WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 Gene3D G3DSA:3.30.70.20 145 218 2.9E-23 T 28-03-2018 WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 Gene3D G3DSA:3.30.70.20 108 144 8.1E-19 T 28-03-2018 WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 Pfam PF00037 4Fe-4S binding domain 40 56 1.7E-4 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 Gene3D G3DSA:3.30.70.20 49 107 4.4E-17 T 28-03-2018 WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 Pfam PF13247 4Fe-4S dicluster domain 84 181 1.0E-24 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 SUPERFAMILY SSF54862 36 215 3.98E-64 T 28-03-2018 WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 125 136 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS21780 d9e194dbafe0054b5cf056183be73e01 223 Gene3D G3DSA:3.30.70.20 19 48 2.6E-4 T 28-03-2018 WM46_RS17595 f347ae610774f098cf84fa68fd4c0194 95 Hamap MF_01564 Protein TusB [tusB]. 1 95 29.623 T 28-03-2018 IPR023526 Sulphur relay, TusB GO:0002143|GO:0005737 WM46_RS17595 f347ae610774f098cf84fa68fd4c0194 95 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 2 95 2.4E-32 T 28-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 WM46_RS17595 f347ae610774f098cf84fa68fd4c0194 95 Pfam PF04077 DsrH like protein 8 91 2.5E-28 T 28-03-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 WM46_RS17595 f347ae610774f098cf84fa68fd4c0194 95 SUPERFAMILY SSF75169 1 95 3.53E-29 T 28-03-2018 IPR027396 DsrEFH-like WM46_RS17595 f347ae610774f098cf84fa68fd4c0194 95 Gene3D G3DSA:3.40.1260.10 1 93 7.4E-20 T 28-03-2018 WM46_RS25810 234d01575225e2e72751d318530b5d6d 342 Pfam PF14390 Putative PD-(D/E)XK family member, (DUF4420) 12 317 6.9E-66 T 28-03-2018 IPR025534 Putative PD-(D/E)XK family member (DUF4420) WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 184 1.5E-7 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 1.5E-7 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 1.5E-7 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 1.5E-7 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 1.5E-7 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 SUPERFAMILY SSF103473 244 452 1.57E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 SUPERFAMILY SSF103473 8 194 1.57E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 Gene3D G3DSA:1.20.1250.20 255 468 7.6E-23 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 Pfam PF07690 Major Facilitator Superfamily 15 405 5.2E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 Gene3D G3DSA:1.20.1250.20 4 196 4.5E-33 T 28-03-2018 WM46_RS02730 cac4dec95525bfbae36dd5c68aebebe8 470 Hamap MF_01577 Putative multidrug resistance protein MdtD [mdtD]. 1 465 49.893 T 28-03-2018 IPR023721 Multidrug resistance protein MdtD, putative WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 Gene3D G3DSA:2.40.160.10 32 374 4.4E-57 T 28-03-2018 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 Pfam PF00267 Gram-negative porin 27 374 4.3E-146 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 SUPERFAMILY SSF56935 22 374 1.2E-82 T 28-03-2018 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 243 255 1.7E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 152 163 1.7E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 52 63 1.7E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 95 105 1.7E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 325 342 1.7E-17 T 28-03-2018 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00183 E.coli/Salmonella-type porin signature 95 117 5.9E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00183 E.coli/Salmonella-type porin signature 22 38 5.9E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00183 E.coli/Salmonella-type porin signature 278 297 5.9E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00183 E.coli/Salmonella-type porin signature 51 69 5.9E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00183 E.coli/Salmonella-type porin signature 249 266 5.9E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS06265 9f8642e6d4d320487ce5bd16da547353 374 PRINTS PR00183 E.coli/Salmonella-type porin signature 150 172 5.9E-71 T 28-03-2018 IPR001897 Porin, gammaproteobacterial GO:0006810|GO:0015288|GO:0016020 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 Gene3D G3DSA:1.10.1140.10 348 458 1.5E-45 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 333 342 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 SUPERFAMILY SSF50615 3 75 1.75E-24 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 Gene3D G3DSA:3.40.50.300 76 347 7.2E-91 T 28-03-2018 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 Gene3D G3DSA:2.40.10.170 1 75 5.7E-30 T 28-03-2018 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 SUPERFAMILY SSF47917 345 459 4.45E-55 T 28-03-2018 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 130 342 3.8E-64 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 SMART SM00382 142 327 4.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 SUPERFAMILY SSF52540 77 348 1.02E-90 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 460 56.961 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 460 1.0E-262 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 WM46_RS19525 a9387f5ce9366b76e6bafb796a2f303b 460 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 72 3.6E-20 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS11810 8651e3e33860e60ab0231ae2c13f7444 361 Pfam PF13360 PQQ-like domain 78 335 2.5E-5 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS11810 8651e3e33860e60ab0231ae2c13f7444 361 SMART SM00564 153 187 34.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS11810 8651e3e33860e60ab0231ae2c13f7444 361 SMART SM00564 198 229 670.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS11810 8651e3e33860e60ab0231ae2c13f7444 361 SMART SM00564 104 138 12.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS11810 8651e3e33860e60ab0231ae2c13f7444 361 Gene3D G3DSA:2.130.10.10 41 359 1.5E-45 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 WM46_RS11810 8651e3e33860e60ab0231ae2c13f7444 361 SUPERFAMILY SSF51004 50 347 2.22E-42 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain WM46_RS26090 a4569217abc763eab3b2131f86a22632 571 Gene3D G3DSA:1.10.150.130 217 344 7.9E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS26090 a4569217abc763eab3b2131f86a22632 571 Gene3D G3DSA:1.10.443.10 347 567 1.6E-28 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS26090 a4569217abc763eab3b2131f86a22632 571 Pfam PF00589 Phage integrase family 377 548 7.8E-16 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS26090 a4569217abc763eab3b2131f86a22632 571 Pfam PF12482 Phage integrase protein 100 190 2.1E-27 T 28-03-2018 IPR022169 Protein of unknown function DUF3701 WM46_RS26090 a4569217abc763eab3b2131f86a22632 571 SUPERFAMILY SSF56349 224 558 3.24E-33 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 Gene3D G3DSA:1.10.10.60 171 226 3.6E-7 T 28-03-2018 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 Pfam PF02311 AraC-like ligand binding domain 22 143 1.1E-20 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 3.9E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 3.9E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 SUPERFAMILY SSF46689 228 276 9.41E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 SUPERFAMILY SSF51215 27 161 3.4E-16 T 28-03-2018 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 Gene3D G3DSA:1.10.10.60 227 281 6.1E-13 T 28-03-2018 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 Hamap MF_01533 HTH-type transcriptional activator RhaR [rhaR]. 1 282 49.937 T 28-03-2018 IPR023699 Transcription activator HTH, RhaR GO:0003700|GO:0005737|GO:0019299|GO:0045893 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 Gene3D G3DSA:2.60.120.280 6 166 7.7E-20 T 28-03-2018 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 Pfam PF12833 Helix-turn-helix domain 199 275 6.4E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 SMART SM00342 192 275 2.5E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS18555 39fbe01baf3c7558f23473a38a01bece 282 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS24415 02ce4cf2f6ab458ee788a1bff391c39a 593 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 4 344 4.1E-115 T 28-03-2018 IPR016624 Uncharacterised conserved protein UCP014753 WM46_RS24415 02ce4cf2f6ab458ee788a1bff391c39a 593 PIRSF PIRSF014753 1 576 2.4E-152 T 28-03-2018 IPR016624 Uncharacterised conserved protein UCP014753 WM46_RS24070 89a9e4ec1b6ce38f1a2702b99a18f37a 59 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 7 54 18.67 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 WM46_RS24070 89a9e4ec1b6ce38f1a2702b99a18f37a 59 PIRSF PIRSF036466 7 59 1.3E-20 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 WM46_RS24070 89a9e4ec1b6ce38f1a2702b99a18f37a 59 Pfam PF07043 Protein of unknown function (DUF1328) 12 50 2.7E-13 T 28-03-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 WM46_RS10300 dd1e76b563d3ce3de8a99f301a20b279 252 Gene3D G3DSA:3.40.50.720 1 249 8.4E-75 T 28-03-2018 WM46_RS10300 dd1e76b563d3ce3de8a99f301a20b279 252 SUPERFAMILY SSF69572 3 248 3.79E-85 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 WM46_RS10300 dd1e76b563d3ce3de8a99f301a20b279 252 TIGRFAM TIGR02355 moeB: molybdopterin synthase sulfurylase MoeB 8 247 2.5E-132 T 28-03-2018 IPR012730 Molybdopterin synthase sulfurylase MoeB GO:0006777 MetaCyc: PWY-6823 WM46_RS10300 dd1e76b563d3ce3de8a99f301a20b279 252 Pfam PF00899 ThiF family 12 244 1.9E-61 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 WM46_RS07820 f006effa31b98389e75c02abd5f7f5de 331 Gene3D G3DSA:2.40.440.10 91 234 9.9E-30 T 28-03-2018 WM46_RS07820 f006effa31b98389e75c02abd5f7f5de 331 SUPERFAMILY SSF141523 95 232 2.62E-29 T 28-03-2018 WM46_RS07820 f006effa31b98389e75c02abd5f7f5de 331 Pfam PF01476 LysM domain 42 85 2.4E-8 T 28-03-2018 IPR018392 LysM domain WM46_RS07820 f006effa31b98389e75c02abd5f7f5de 331 Pfam PF03734 L,D-transpeptidase catalytic domain 97 232 1.3E-20 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 WM46_RS07820 f006effa31b98389e75c02abd5f7f5de 331 SMART SM00257 41 85 5.7E-5 T 28-03-2018 IPR018392 LysM domain WM46_RS07820 f006effa31b98389e75c02abd5f7f5de 331 Gene3D G3DSA:3.10.350.10 39 87 1.1E-7 T 28-03-2018 WM46_RS06775 582fd897372530e9925bc32593e29db7 293 Pfam PF00892 EamA-like transporter family 6 137 3.1E-6 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS06775 582fd897372530e9925bc32593e29db7 293 Pfam PF00892 EamA-like transporter family 158 285 1.2E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS06775 582fd897372530e9925bc32593e29db7 293 SUPERFAMILY SSF103481 190 291 1.31E-7 T 28-03-2018 WM46_RS06775 582fd897372530e9925bc32593e29db7 293 SUPERFAMILY SSF103481 52 139 5.89E-5 T 28-03-2018 WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 Gene3D G3DSA:3.30.70.20 106 171 1.8E-7 T 28-03-2018 WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 SUPERFAMILY SSF54862 33 153 2.97E-29 T 28-03-2018 WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 Gene3D G3DSA:3.30.70.20 22 70 8.3E-7 T 28-03-2018 WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 16 137 2.5E-51 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 Pfam PF12838 4Fe-4S dicluster domain 59 113 1.3E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 Gene3D G3DSA:3.30.70.20 71 105 9.7E-15 T 28-03-2018 WM46_RS01795 8890a645cf3489765f245d9620c4c598 180 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 163 27.027 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS23035 d9ff42f3bba8973b5585b973d0999dbd 323 Pfam PF00892 EamA-like transporter family 3 136 1.9E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS23035 d9ff42f3bba8973b5585b973d0999dbd 323 SUPERFAMILY SSF103481 222 310 1.31E-5 T 28-03-2018 WM46_RS23035 d9ff42f3bba8973b5585b973d0999dbd 323 SUPERFAMILY SSF103481 43 139 6.67E-9 T 28-03-2018 WM46_RS25365 57ed1c7e2cd2fd8f5c3c2b784cbd9000 373 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 371 5.0E-177 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 WM46_RS25365 57ed1c7e2cd2fd8f5c3c2b784cbd9000 373 Pfam PF01924 Hydrogenase formation hypA family 14 367 1.6E-151 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 WM46_RS25365 57ed1c7e2cd2fd8f5c3c2b784cbd9000 373 PIRSF PIRSF005622 1 372 1.4E-159 T 28-03-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 4 130 6.0E-46 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 SUPERFAMILY SSF81330 12 126 2.22E-36 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 132 1.3E-60 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 Gene3D G3DSA:1.20.5.220 118 133 1.9E-4 T 28-03-2018 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 133 31.264 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 1.3E-14 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 1.3E-14 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 1.3E-14 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 WM46_RS17395 d8739f27b39dcdf25c873d26663f027d 136 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site WM46_RS12315 224145da4f2f7e77fc17f726a49328a6 191 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 166 0.001 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS12315 224145da4f2f7e77fc17f726a49328a6 191 Gene3D G3DSA:2.160.10.10 16 179 1.4E-21 T 28-03-2018 WM46_RS12315 224145da4f2f7e77fc17f726a49328a6 191 SUPERFAMILY SSF51161 32 176 8.59E-26 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 Gene3D G3DSA:1.10.10.10 9 93 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 1.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 Gene3D G3DSA:3.40.190.10 99 182 2.9E-4 T 28-03-2018 WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 SUPERFAMILY SSF53850 102 298 8.69E-23 T 28-03-2018 WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 Pfam PF03466 LysR substrate binding domain 102 295 1.4E-22 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 SUPERFAMILY SSF46785 12 94 7.96E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 Gene3D G3DSA:3.40.190.10 183 267 8.1E-11 T 28-03-2018 WM46_RS24485 0debb5f47fc62254bf07e8afcfba5af8 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 71 2.0E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 ProSitePatterns PS01087 Radical activating enzymes signature. 13 34 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 Gene3D G3DSA:3.80.30.10 121 299 9.1E-30 T 28-03-2018 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 SUPERFAMILY SSF102114 117 265 1.31E-14 T 28-03-2018 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 Pfam PF13353 4Fe-4S single cluster domain 12 153 1.0E-9 T 28-03-2018 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 2 290 7.1E-109 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 Pfam PF04055 Radical SAM superfamily 19 230 1.3E-31 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS10310 8362fce4cff5d7b41565171d42064dc5 299 PIRSF PIRSF000371 1 299 1.5E-94 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Gene3D G3DSA:1.10.274.10 270 387 8.3E-27 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Gene3D G3DSA:3.50.30.10 388 477 3.7E-16 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Gene3D G3DSA:3.30.1340.10 158 243 2.5E-19 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Pfam PF05524 PEP-utilising enzyme, N-terminal 260 370 2.2E-18 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Gene3D G3DSA:3.40.50.510 1 147 3.7E-33 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 SUPERFAMILY SSF53062 1 128 9.03E-31 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 PRINTS PR00107 Phosphocarrier protein signature 209 226 9.4E-6 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 PRINTS PR00107 Phosphocarrier protein signature 194 209 9.4E-6 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 PRINTS PR00107 Phosphocarrier protein signature 169 185 9.4E-6 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Pfam PF00391 PEP-utilising enzyme, mobile domain 396 465 6.7E-14 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 SUPERFAMILY SSF55594 160 243 2.75E-19 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Pfam PF03610 PTS system fructose IIA component 4 120 3.9E-26 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 SUPERFAMILY SSF47831 279 386 1.7E-28 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 159 236 4.0E-14 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 SUPERFAMILY SSF52009 370 472 9.94E-21 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 2 127 2.9E-41 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain WM46_RS05220 bc66c54b2eda84c0c0cfae396e889c3b 477 Pfam PF00381 PTS HPr component phosphorylation site 160 237 9.4E-17 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 Gene3D G3DSA:3.40.605.10 1 258 3.6E-74 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 Pfam PF00171 Aldehyde dehydrogenase family 9 458 2.1E-115 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 TIGRFAM TIGR03240 arg_catab_astD: succinylglutamate-semialdehyde dehydrogenase 3 486 6.0E-252 T 28-03-2018 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 SUPERFAMILY SSF53720 3 455 3.8E-119 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 Hamap MF_01174 N-succinylglutamate 5-semialdehyde dehydrogenase [astD]. 1 486 57.959 T 28-03-2018 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71 WM46_RS08185 e8567915d009be6b3e46b611cec19319 492 Gene3D G3DSA:3.40.309.10 259 453 4.5E-41 T 28-03-2018 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 ProSitePatterns PS00324 Aspartokinase signature. 14 22 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 PIRSF PIRSF000727 12 810 1.4E-298 T 28-03-2018 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+2.7.2.4+1.1.1.3|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4+1.1.1.3|KEGG: 00300+2.7.2.4+1.1.1.3|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 SUPERFAMILY SSF53633 12 299 1.57E-53 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 SUPERFAMILY SSF55347 608 791 2.62E-47 T 28-03-2018 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 15 452 9.8E-63 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 Gene3D G3DSA:3.40.1160.10 9 318 2.5E-47 T 28-03-2018 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 SUPERFAMILY SSF51735 457 630 3.94E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 Gene3D G3DSA:3.40.50.720 455 629 1.5E-24 T 28-03-2018 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 Gene3D G3DSA:3.30.360.10 630 787 1.3E-50 T 28-03-2018 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 Pfam PF00696 Amino acid kinase family 12 284 3.7E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 465 600 1.4E-24 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 Pfam PF00742 Homoserine dehydrogenase 608 803 4.3E-44 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM46_RS20895 e2791770fa4eead68e0232f5a269b4d7 810 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 654 676 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 WM46_RS05505 aae7fd1b5059d0f9391f357abf107768 271 SUPERFAMILY SSF52540 6 244 6.71E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05505 aae7fd1b5059d0f9391f357abf107768 271 SMART SM00382 41 226 4.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS05505 aae7fd1b5059d0f9391f357abf107768 271 Gene3D G3DSA:3.40.50.300 12 244 1.7E-59 T 28-03-2018 WM46_RS05505 aae7fd1b5059d0f9391f357abf107768 271 Pfam PF00005 ABC transporter 33 181 3.6E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 SUPERFAMILY SSF47729 1 90 1.35E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.3E-33 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.0E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.0E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.0E-19 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 SMART SM00411 1 90 2.3E-43 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 WM46_RS21270 1bb50092fec0dda32954ed0fac5a61aa 90 Gene3D G3DSA:4.10.520.10 1 90 1.2E-33 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 Pfam PF13393 Histidyl-tRNA synthetase 10 312 1.3E-46 T 28-03-2018 WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 Pfam PF03129 Anticodon binding domain 340 420 6.7E-10 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 PIRSF PIRSF001549 2 423 1.4E-128 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 SUPERFAMILY SSF55681 5 318 6.77E-104 T 28-03-2018 WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 Gene3D G3DSA:3.40.50.800 326 424 7.8E-17 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 411 1.4E-155 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 SUPERFAMILY SSF52954 329 422 2.29E-24 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 Gene3D G3DSA:3.30.930.10 2 325 7.2E-74 T 28-03-2018 WM46_RS00710 3427eaab4e35276d9230b1c48a30f3c1 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 421 33.715 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 SUPERFAMILY SSF53067 13 263 1.2E-58 T 28-03-2018 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 301 467 3.3E-17 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 Gene3D G3DSA:3.30.420.40 258 515 9.6E-41 T 28-03-2018 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 Hamap MF_02053 Autoinducer-2 kinase [lsrK]. 15 530 76.26 T 28-03-2018 IPR033676 Autoinducer-2 kinase GO:0009372|GO:0071518 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 SUPERFAMILY SSF53067 262 512 2.78E-46 T 28-03-2018 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 13 260 5.1E-51 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 PIRSF PIRSF000538 11 519 9.6E-119 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS23695 c504a4204ea21db14c6be890599a5069 530 Gene3D G3DSA:3.30.420.40 9 257 5.8E-64 T 28-03-2018 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 146 2.4E-46 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 Gene3D G3DSA:2.60.40.10 149 248 2.4E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 100 117 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 SUPERFAMILY SSF49584 140 240 9.29E-18 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 SUPERFAMILY SSF49354 18 146 1.11E-43 T 28-03-2018 IPR008962 PapD-like WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 PRINTS PR00969 Pili chaperone signature 73 94 1.5E-35 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 PRINTS PR00969 Pili chaperone signature 163 178 1.5E-35 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 PRINTS PR00969 Pili chaperone signature 24 33 1.5E-35 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 PRINTS PR00969 Pili chaperone signature 128 143 1.5E-35 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 PRINTS PR00969 Pili chaperone signature 101 118 1.5E-35 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 Gene3D G3DSA:2.60.40.10 23 147 2.5E-40 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS19975 c81796b79cf9a32b17c4910292a05912 248 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 168 238 7.5E-16 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS14970 d276d629e74ef3b72f0a27606f9c7ba1 236 Gene3D G3DSA:3.40.50.300 52 226 2.2E-29 T 28-03-2018 WM46_RS14970 d276d629e74ef3b72f0a27606f9c7ba1 236 Gene3D G3DSA:3.40.50.300 8 51 5.3E-4 T 28-03-2018 WM46_RS14970 d276d629e74ef3b72f0a27606f9c7ba1 236 SUPERFAMILY SSF52540 32 219 9.9E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS11765 cafd196681674d5a50eb606efcb9f5c6 122 Pfam PF04237 YjbR 15 106 4.6E-24 T 28-03-2018 IPR007351 Uncharacterised protein YjbR WM46_RS11765 cafd196681674d5a50eb606efcb9f5c6 122 SUPERFAMILY SSF142906 12 120 6.28E-37 T 28-03-2018 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 Gene3D G3DSA:2.30.22.10 174 230 1.2E-17 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 Hamap MF_01151 Protein GrpE [grpE]. 31 230 20.691 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 PRINTS PR00773 GrpE protein signature 182 197 3.0E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 PRINTS PR00773 GrpE protein signature 209 228 3.0E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 PRINTS PR00773 GrpE protein signature 99 115 3.0E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 PRINTS PR00773 GrpE protein signature 127 142 3.0E-25 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 SUPERFAMILY SSF51064 175 231 8.5E-16 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 ProSitePatterns PS01071 grpE protein signature. 185 228 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 SUPERFAMILY SSF58014 83 174 5.49E-27 T 28-03-2018 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 Gene3D G3DSA:3.90.20.20 69 173 5.4E-31 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 WM46_RS00165 27e956dbc7e5cbb4a044fed6a6782d85 233 Pfam PF01025 GrpE 71 230 4.1E-46 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 WM46_RS19010 7d2602908bf24699da5aa2befa088205 201 Gene3D G3DSA:3.30.1050.10 13 125 2.1E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS19010 7d2602908bf24699da5aa2befa088205 201 Pfam PF02036 SCP-2 sterol transfer family 15 112 9.1E-21 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS19010 7d2602908bf24699da5aa2befa088205 201 SUPERFAMILY SSF55718 10 111 2.47E-7 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 SMART SM00382 344 514 4.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 SMART SM00382 28 230 7.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Pfam PF00005 ABC transporter 336 469 7.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Pfam PF00005 ABC transporter 19 185 1.5E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Gene3D G3DSA:3.40.50.300 292 551 2.1E-58 T 28-03-2018 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 SUPERFAMILY SSF52540 311 501 1.39E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Gene3D G3DSA:3.40.50.300 6 84 3.8E-9 T 28-03-2018 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Pfam PF16326 ABC transporter C-terminal domain 561 629 5.6E-21 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Gene3D G3DSA:3.40.50.300 87 291 5.7E-45 T 28-03-2018 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 SUPERFAMILY SSF52540 9 239 9.77E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09685 0655edba30ab343bb50d6ba0c66e45f8 635 Pfam PF12848 ABC transporter 224 296 2.2E-12 T 28-03-2018 IPR032781 ABC-transporter extension domain WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 Gene3D G3DSA:3.90.180.10 1 151 2.2E-31 T 28-03-2018 WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 2 323 2.5E-142 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 SUPERFAMILY SSF51735 116 284 5.17E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 Pfam PF00107 Zinc-binding dehydrogenase 158 282 2.1E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 Gene3D G3DSA:3.40.50.720 152 267 7.6E-16 T 28-03-2018 WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 SMART SM00829 12 321 1.7E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS17190 6f9bb4d71366852ee01aad8f7ef4d35a 324 SUPERFAMILY SSF50129 1 144 1.89E-46 T 28-03-2018 IPR011032 GroES-like WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 SUPERFAMILY SSF53163 4 145 3.4E-35 T 28-03-2018 IPR023430 Peptidase HybD-like domain WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 Pfam PF01750 Hydrogenase maturation protease 23 138 6.6E-30 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 TIGRFAM TIGR00142 hycI: hydrogenase maturation peptidase HycI 3 146 9.5E-67 T 28-03-2018 IPR004420 Peptidase A31, hydrogenase maturation protease HycI GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 PRINTS PR00446 Hydrogen uptake protein signature 67 83 5.6E-14 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 PRINTS PR00446 Hydrogen uptake protein signature 33 50 5.6E-14 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 PRINTS PR00446 Hydrogen uptake protein signature 3 15 5.6E-14 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 PRINTS PR00446 Hydrogen uptake protein signature 15 26 5.6E-14 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 PRINTS PR00446 Hydrogen uptake protein signature 56 66 5.6E-14 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 Gene3D G3DSA:3.40.50.1450 3 153 3.3E-34 T 28-03-2018 IPR023430 Peptidase HybD-like domain WM46_RS25425 fd5c89114f33f4e977c989ca9d933722 154 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 139 5.4E-36 T 28-03-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 Gene3D G3DSA:1.20.58.340 256 327 3.4E-15 T 28-03-2018 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 Hamap MF_01565 Zinc transport protein ZntB [zntB]. 1 327 71.695 T 28-03-2018 IPR023714 Zinc transport protein ZntB GO:0005385|GO:0005886|GO:0071577 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 Gene3D G3DSA:3.30.460.20 1 139 5.1E-20 T 28-03-2018 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 SUPERFAMILY SSF144083 265 324 1.02E-12 T 28-03-2018 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 Pfam PF01544 CorA-like Mg2+ transporter protein 40 323 1.0E-62 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 SUPERFAMILY SSF143865 10 255 1.96E-48 T 28-03-2018 WM46_RS06225 84ae13f5115a7d8f6dd754c922c54fdd 327 Gene3D G3DSA:1.20.58.340 140 255 3.6E-17 T 28-03-2018 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 5.3E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 Gene3D G3DSA:1.10.10.10 118 214 8.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 SUPERFAMILY SSF46894 148 212 6.46E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS08955 4e2d6068276adbd575d8cd441052dc7a 216 SMART SM00421 153 210 6.8E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20405 1d9ba39d9c60fefabffebc1cd29f6cfb 134 Pfam PF00486 Transcriptional regulatory protein, C terminal 52 115 6.1E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS20405 1d9ba39d9c60fefabffebc1cd29f6cfb 134 SUPERFAMILY SSF46894 42 115 1.42E-9 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS20405 1d9ba39d9c60fefabffebc1cd29f6cfb 134 Gene3D G3DSA:1.10.10.10 35 122 6.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21300 a12304eef871911d37f92b845f21505e 529 Gene3D G3DSA:3.40.140.20 226 375 5.4E-56 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 Gene3D G3DSA:3.40.140.20 376 519 4.7E-53 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 SMART SM00798 137 461 3.0E-217 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 460 1.4E-119 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 SUPERFAMILY SSF53927 221 529 3.91E-130 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 529 45.427 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 Gene3D G3DSA:3.40.50.1380 1 196 1.4E-78 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS21300 a12304eef871911d37f92b845f21505e 529 Pfam PF02142 MGS-like domain 19 132 6.9E-30 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS21300 a12304eef871911d37f92b845f21505e 529 PIRSF PIRSF000414 1 529 4.8E-228 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 529 8.7E-268 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS21300 a12304eef871911d37f92b845f21505e 529 SUPERFAMILY SSF52335 7 197 2.62E-72 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS21300 a12304eef871911d37f92b845f21505e 529 SMART SM00851 19 132 2.5E-62 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain WM46_RS22625 1db7161e76e29222f3bd2baf3846f3ee 318 Gene3D G3DSA:1.10.3530.10 31 207 1.9E-68 T 28-03-2018 IPR023136 Api92-like domain WM46_RS22625 1db7161e76e29222f3bd2baf3846f3ee 318 SUPERFAMILY SSF160940 3 280 9.29E-121 T 28-03-2018 WM46_RS22625 1db7161e76e29222f3bd2baf3846f3ee 318 Pfam PF06924 Protein of unknown function (DUF1281) 9 141 1.9E-49 T 28-03-2018 IPR009694 Protein of unknown function DUF1281 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 SMART SM01116 83 156 8.0E-46 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 Gene3D G3DSA:3.30.1160.10 89 155 4.4E-35 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 SUPERFAMILY SSF55234 88 155 2.88E-29 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 TIGRFAM TIGR00673 cynS: cyanase 1 156 1.2E-69 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 Gene3D G3DSA:1.10.260.40 1 88 9.5E-9 T 28-03-2018 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 SUPERFAMILY SSF47413 1 85 1.65E-20 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 Hamap MF_00535 Cyanate hydratase [cynS]. 1 156 75.978 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 Pfam PF02560 Cyanate lyase C-terminal domain 87 154 5.8E-32 T 28-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 PIRSF PIRSF001263 3 156 5.4E-66 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 PRINTS PR01693 Cyanase signature 91 105 1.6E-35 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 PRINTS PR01693 Cyanase signature 109 125 1.6E-35 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 PRINTS PR01693 Cyanase signature 141 151 1.6E-35 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 PRINTS PR01693 Cyanase signature 22 37 1.6E-35 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS01380 2e96e251facbd9134e6789165a91fd6c 156 PRINTS PR01693 Cyanase signature 42 59 1.6E-35 T 28-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 410 418 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 Pfam PF06628 Catalase-related immune-responsive 498 561 4.2E-16 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 SUPERFAMILY SSF56634 45 581 2.75E-224 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 Gene3D G3DSA:2.40.180.10 50 435 3.4E-165 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 SUPERFAMILY SSF52317 597 743 5.95E-13 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PIRSF PIRSF038927 47 750 0.0 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PRINTS PR00067 Catalase signature 156 174 2.8E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PRINTS PR00067 Catalase signature 365 392 2.8E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PRINTS PR00067 Catalase signature 196 214 2.8E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PRINTS PR00067 Catalase signature 177 194 2.8E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PRINTS PR00067 Catalase signature 93 116 2.8E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 PRINTS PR00067 Catalase signature 397 423 2.8E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 ProSitePatterns PS00438 Catalase proximal active site signature. 116 132 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 SMART SM01060 80 468 1.7E-273 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS08115 984798d0a4441a17080f5627697c1977 752 Gene3D G3DSA:3.40.50.880 597 747 2.6E-15 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS08115 984798d0a4441a17080f5627697c1977 752 Pfam PF00199 Catalase 80 465 1.8E-177 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 WM46_RS18285 156c42412d9c58265ab4a217243e1206 140 PIRSF PIRSF003230 3 136 8.5E-21 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM46_RS18285 156c42412d9c58265ab4a217243e1206 140 SUPERFAMILY SSF54637 7 136 4.44E-34 T 28-03-2018 IPR029069 HotDog domain WM46_RS18285 156c42412d9c58265ab4a217243e1206 140 Gene3D G3DSA:3.10.129.10 2 136 1.5E-27 T 28-03-2018 WM46_RS18285 156c42412d9c58265ab4a217243e1206 140 Pfam PF13279 Thioesterase-like superfamily 17 120 5.9E-13 T 28-03-2018 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 SUPERFAMILY SSF53335 92 456 4.53E-79 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS03725 8aa54148852528d4703387e7ad883629 477 Pfam PF00145 C-5 cytosine-specific DNA methylase 92 455 1.2E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS03725 8aa54148852528d4703387e7ad883629 477 Gene3D G3DSA:3.40.50.150 84 313 6.5E-59 T 28-03-2018 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 94 455 6.6E-103 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 222 236 2.4E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 93 109 2.4E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 276 289 2.4E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 174 186 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 WM46_RS03725 8aa54148852528d4703387e7ad883629 477 Gene3D G3DSA:3.90.120.10 314 443 6.8E-24 T 28-03-2018 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 SUPERFAMILY SSF52540 1 205 1.24E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 208 320 3.9E-34 T 28-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 SUPERFAMILY SSF48019 209 328 4.08E-34 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 Gene3D G3DSA:1.20.272.10 208 329 1.3E-22 T 28-03-2018 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 Gene3D G3DSA:3.40.50.300 8 165 1.3E-22 T 28-03-2018 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 13 201 1.9E-59 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 Pfam PF13177 DNA polymerase III, delta subunit 12 166 3.0E-40 T 28-03-2018 WM46_RS08650 7ab0e69fe17a0bb9a72530b878fe5054 334 Gene3D G3DSA:1.10.8.10 169 205 4.0E-15 T 28-03-2018 WM46_RS19950 c112cdf206b6d4495208fc4af5b6ac88 285 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 20 285 8.5E-86 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 SUPERFAMILY SSF100950 225 490 3.1E-71 T 28-03-2018 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 2 212 1.7E-66 T 28-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 Gene3D G3DSA:3.40.1080.10 229 487 1.2E-48 T 28-03-2018 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 Gene3D G3DSA:3.40.1080.10 7 213 2.9E-33 T 28-03-2018 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 SUPERFAMILY SSF100950 7 218 2.36E-60 T 28-03-2018 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 6 490 7.4E-226 T 28-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 WM46_RS10685 afcbf37a33afb4ddd19111229cbe3fbd 492 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 317 461 8.0E-41 T 28-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain WM46_RS01845 456001e3c74100336fff9170541e1991 432 Gene3D G3DSA:3.60.120.10 1 431 5.2E-93 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS01845 456001e3c74100336fff9170541e1991 432 Hamap MF_01935 Isochorismate synthase MenF [menF]. 3 430 30.212 T 28-03-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 WM46_RS01845 456001e3c74100336fff9170541e1991 432 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 93 427 3.2E-111 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 WM46_RS01845 456001e3c74100336fff9170541e1991 432 Pfam PF00425 chorismate binding enzyme 169 420 8.4E-64 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal WM46_RS01845 456001e3c74100336fff9170541e1991 432 SUPERFAMILY SSF56322 20 428 3.92E-101 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS18165 69656090b6ad8b8bc6a02298333b3d9b 352 TIGRFAM TIGR00439 ftsX: putative protein insertion permease FtsX 46 351 5.3E-157 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 WM46_RS18165 69656090b6ad8b8bc6a02298333b3d9b 352 PIRSF PIRSF003097 50 348 1.8E-107 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 Pfam PF01306 LacY proton/sugar symporter 11 403 6.6E-107 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 TIGRFAM TIGR00882 2A0105: oligosaccharide:H+ symporter 11 397 2.2E-107 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 311 330 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 342 362 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 102 124 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 67 96 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 256 277 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 210 238 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 144 162 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 PRINTS PR00174 LacY proton/sugar symporter family signature 280 306 3.0E-58 T 28-03-2018 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 SUPERFAMILY SSF103473 13 398 4.01E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 Gene3D G3DSA:1.20.1250.20 202 401 3.3E-22 T 28-03-2018 WM46_RS24405 25a9255ad796d3a48e4e90d6987b8048 415 Gene3D G3DSA:1.20.1250.20 5 197 3.8E-13 T 28-03-2018 WM46_RS19905 a3628b1c9442b990af34ba8f626ec2c5 104 Gene3D G3DSA:3.40.50.2300 2 104 1.4E-36 T 28-03-2018 WM46_RS19905 a3628b1c9442b990af34ba8f626ec2c5 104 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 6.0E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS19905 a3628b1c9442b990af34ba8f626ec2c5 104 SUPERFAMILY SSF52794 1 101 1.49E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 SMART SM01329 6 355 1.5E-201 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 6 354 1.9E-172 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 5 359 51.889 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 Gene3D G3DSA:3.40.718.10 1 363 3.4E-132 T 28-03-2018 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 SUPERFAMILY SSF53659 2 360 5.76E-123 T 28-03-2018 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 355 4.2E-139 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM46_RS14460 7bf7bc626d3c92600911ba86f0875ccf 363 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 247 266 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 SUPERFAMILY SSF52009 350 468 4.32E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 PIRSF PIRSF000854 4 792 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 483 789 9.4E-59 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 SUPERFAMILY SSF56059 7 386 2.12E-108 T 28-03-2018 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 22 350 2.7E-120 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Gene3D G3DSA:3.50.30.10 360 478 1.5E-35 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Gene3D G3DSA:3.20.20.60 480 792 5.1E-103 T 28-03-2018 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 SUPERFAMILY SSF51621 467 790 1.39E-95 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 9 792 0.0 T 28-03-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Gene3D G3DSA:3.30.470.20 198 359 1.0E-44 T 28-03-2018 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Gene3D G3DSA:3.30.1490.20 6 197 2.8E-54 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS07955 15c19d29540a0fc6c4494af09d75219d 792 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 1.0E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 91 7.5E-23 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 Pfam PF00589 Phage integrase family 113 280 1.3E-52 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 294 58.189 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 Gene3D G3DSA:1.10.443.10 114 288 1.7E-43 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 SUPERFAMILY SSF47823 8 98 6.28E-10 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 10 296 9.0E-109 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 SUPERFAMILY SSF56349 107 292 1.88E-54 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS19105 d8b9cac070081325697e1ae11ae2f60c 298 Gene3D G3DSA:1.10.150.130 2 113 2.0E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS16435 881591a2aa9cfd190ea6e161195836c4 134 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 19 127 2.0E-22 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III WM46_RS24780 1d79d7366bead9cf220adce82f0aaefa 108 Gene3D G3DSA:2.60.120.10 1 108 8.3E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS24780 1d79d7366bead9cf220adce82f0aaefa 108 PIRSF PIRSF029883 1 108 1.7E-36 T 28-03-2018 IPR025499 Pectin degradation protein KdgF WM46_RS24780 1d79d7366bead9cf220adce82f0aaefa 108 SUPERFAMILY SSF51182 7 100 1.78E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS24780 1d79d7366bead9cf220adce82f0aaefa 108 Pfam PF07883 Cupin domain 33 90 6.3E-15 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS16665 f87347d309aa5d258be3ee24217b435b 131 Gene3D G3DSA:3.40.1350.10 22 131 4.9E-35 T 28-03-2018 WM46_RS16665 f87347d309aa5d258be3ee24217b435b 131 Hamap MF_00048 UPF0102 protein YraN [yraN]. 16 128 23.735 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 WM46_RS16665 f87347d309aa5d258be3ee24217b435b 131 SUPERFAMILY SSF52980 17 126 1.61E-23 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS16665 f87347d309aa5d258be3ee24217b435b 131 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 16 129 9.3E-54 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 WM46_RS16665 f87347d309aa5d258be3ee24217b435b 131 Pfam PF02021 Uncharacterised protein family UPF0102 24 114 1.2E-24 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 WM46_RS17605 cd21c01f6b5ad4881a99bc0ba0764f21 128 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 2 128 3.6E-55 T 28-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 WM46_RS17605 cd21c01f6b5ad4881a99bc0ba0764f21 128 Pfam PF02635 DsrE/DsrF-like family 1 128 4.7E-29 T 28-03-2018 IPR003787 Sulphur relay, DsrE/F-like protein WM46_RS17605 cd21c01f6b5ad4881a99bc0ba0764f21 128 Hamap MF_00390 Sulfurtransferase TusD [tusD]. 1 128 40.82 T 28-03-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 WM46_RS17605 cd21c01f6b5ad4881a99bc0ba0764f21 128 Gene3D G3DSA:3.40.1260.10 1 128 1.1E-31 T 28-03-2018 WM46_RS17605 cd21c01f6b5ad4881a99bc0ba0764f21 128 SUPERFAMILY SSF75169 1 128 1.94E-38 T 28-03-2018 IPR027396 DsrEFH-like WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 Gene3D G3DSA:3.40.720.10 22 471 4.1E-130 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 SMART SM00098 65 471 3.0E-227 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 Pfam PF00245 Alkaline phosphatase 64 430 4.1E-129 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 ProSitePatterns PS00123 Alkaline phosphatase active site. 121 129 - T 28-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 SUPERFAMILY SSF53649 35 470 4.84E-139 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 PRINTS PR00113 Alkaline phosphatase signature 121 136 1.3E-49 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 PRINTS PR00113 Alkaline phosphatase signature 64 84 1.3E-49 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 PRINTS PR00113 Alkaline phosphatase signature 320 349 1.3E-49 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 PRINTS PR00113 Alkaline phosphatase signature 221 231 1.3E-49 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS12985 fcfb961ef7173734f830dbadd46447b4 471 PRINTS PR00113 Alkaline phosphatase signature 158 178 1.3E-49 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 WM46_RS25075 4b59f870e7a4f4d7e86b8f3afa01f2d2 149 SUPERFAMILY SSF52218 1 148 2.73E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25075 4b59f870e7a4f4d7e86b8f3afa01f2d2 149 PRINTS PR00369 Flavodoxin signature 53 64 2.2E-6 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS25075 4b59f870e7a4f4d7e86b8f3afa01f2d2 149 PRINTS PR00369 Flavodoxin signature 108 127 2.2E-6 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS25075 4b59f870e7a4f4d7e86b8f3afa01f2d2 149 PRINTS PR00369 Flavodoxin signature 84 94 2.2E-6 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS25075 4b59f870e7a4f4d7e86b8f3afa01f2d2 149 Pfam PF00258 Flavodoxin 6 139 2.8E-24 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS25075 4b59f870e7a4f4d7e86b8f3afa01f2d2 149 Gene3D G3DSA:3.40.50.360 1 148 3.2E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS13930 9fc11e3dc55c43eec943ebb5d67f4e7c 161 PIRSF PIRSF002094 1 161 1.8E-50 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 WM46_RS13930 9fc11e3dc55c43eec943ebb5d67f4e7c 161 Gene3D G3DSA:3.30.910.20 83 161 7.0E-13 T 28-03-2018 WM46_RS13930 9fc11e3dc55c43eec943ebb5d67f4e7c 161 Gene3D G3DSA:3.30.910.20 10 82 2.6E-9 T 28-03-2018 WM46_RS13930 9fc11e3dc55c43eec943ebb5d67f4e7c 161 SUPERFAMILY SSF111384 20 160 8.24E-32 T 28-03-2018 IPR024930 Skp domain WM46_RS13930 9fc11e3dc55c43eec943ebb5d67f4e7c 161 SMART SM00935 10 161 1.2E-39 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 WM46_RS13930 9fc11e3dc55c43eec943ebb5d67f4e7c 161 Pfam PF03938 Outer membrane protein (OmpH-like) 8 159 3.3E-29 T 28-03-2018 IPR005632 Chaperone protein Skp GO:0051082 WM46_RS14200 02d39e6accc4d2d2ad4db848d0f8a20a 81 Gene3D G3DSA:1.10.1790.10 3 80 3.2E-4 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS14200 02d39e6accc4d2d2ad4db848d0f8a20a 81 ProDom PD059807 YMJA ECS1872 1 81 3.0E-25 T 28-03-2018 IPR020251 Uncharacterised protein family, YmjA WM46_RS14200 02d39e6accc4d2d2ad4db848d0f8a20a 81 Pfam PF10820 Protein of unknown function (DUF2543) 1 81 3.1E-48 T 28-03-2018 IPR020251 Uncharacterised protein family, YmjA WM46_RS10175 e84adf262879dc61c806691c39ae0c0e 240 Gene3D G3DSA:3.40.109.10 1 240 1.4E-59 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS10175 e84adf262879dc61c806691c39ae0c0e 240 SUPERFAMILY SSF55469 1 239 1.96E-73 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS10175 e84adf262879dc61c806691c39ae0c0e 240 Pfam PF00881 Nitroreductase family 9 159 1.0E-19 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 WM46_RS10175 e84adf262879dc61c806691c39ae0c0e 240 PIRSF PIRSF005426 1 240 1.4E-84 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 WM46_RS01925 4504d38ad2f201a2cbb0d93b06565b7e 185 SUPERFAMILY SSF56925 61 182 5.81E-9 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS01925 4504d38ad2f201a2cbb0d93b06565b7e 185 Pfam PF07437 YfaZ precursor 6 185 6.2E-85 T 28-03-2018 IPR009998 YfaZ WM46_RS01925 4504d38ad2f201a2cbb0d93b06565b7e 185 Gene3D G3DSA:2.40.160.10 14 185 5.5E-10 T 28-03-2018 WM46_RS19780 a12e569ad1750236a2ff83a77de19542 394 Pfam PF07690 Major Facilitator Superfamily 14 349 9.2E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19780 a12e569ad1750236a2ff83a77de19542 394 Gene3D G3DSA:1.20.1250.20 1 194 3.2E-31 T 28-03-2018 WM46_RS19780 a12e569ad1750236a2ff83a77de19542 394 Gene3D G3DSA:1.20.1250.20 197 390 8.6E-7 T 28-03-2018 WM46_RS19780 a12e569ad1750236a2ff83a77de19542 394 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 51 186 1.2E-39 T 28-03-2018 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 WM46_RS19780 a12e569ad1750236a2ff83a77de19542 394 SUPERFAMILY SSF103473 5 384 4.32E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20230 11bb64103a2787aec9394ff057a155ec 348 Gene3D G3DSA:3.40.50.2000 1 151 1.8E-34 T 28-03-2018 WM46_RS20230 11bb64103a2787aec9394ff057a155ec 348 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 2 343 4.1E-169 T 28-03-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 WM46_RS20230 11bb64103a2787aec9394ff057a155ec 348 SUPERFAMILY SSF53756 1 343 6.09E-101 T 28-03-2018 WM46_RS20230 11bb64103a2787aec9394ff057a155ec 348 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 69 324 1.5E-88 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 WM46_RS20230 11bb64103a2787aec9394ff057a155ec 348 Gene3D G3DSA:3.40.50.2000 163 348 1.4E-43 T 28-03-2018 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 265 380 5.4E-18 T 28-03-2018 IPR000014 PAS domain WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 496 600 9.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 SMART SM00387 495 602 1.7E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 SUPERFAMILY SSF55874 443 602 7.6E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 Pfam PF00989 PAS fold 265 369 1.7E-20 T 28-03-2018 IPR013767 PAS fold GO:0006355 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 Pfam PF00512 His Kinase A (phospho-acceptor) domain 389 450 1.4E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 SMART SM00388 388 453 1.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 SUPERFAMILY SSF55785 253 367 8.9E-19 T 28-03-2018 IPR000014 PAS domain WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 Gene3D G3DSA:3.30.565.10 453 607 6.9E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 Gene3D G3DSA:1.10.287.130 383 449 2.4E-16 T 28-03-2018 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 SUPERFAMILY SSF47384 380 452 2.35E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 Gene3D G3DSA:3.30.450.20 244 382 1.2E-27 T 28-03-2018 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 561 1.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 599 1.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 1.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 533 547 1.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS02065 301050ac1a56feb5223574c351bbc8fd 608 SMART SM00091 262 329 1.9E-10 T 28-03-2018 IPR000014 PAS domain WM46_RS01435 4b1c80adc3d38b863e03d870f9d23587 292 Gene3D G3DSA:3.40.140.10 3 164 2.8E-34 T 28-03-2018 WM46_RS01435 4b1c80adc3d38b863e03d870f9d23587 292 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 7 103 3.4E-23 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM46_RS01435 4b1c80adc3d38b863e03d870f9d23587 292 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 92 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM46_RS01435 4b1c80adc3d38b863e03d870f9d23587 292 SUPERFAMILY SSF53927 6 150 1.95E-38 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 SUPERFAMILY SSF51735 140 306 8.63E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 Gene3D G3DSA:3.40.50.720 148 327 3.0E-30 T 28-03-2018 WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 SMART SM00829 10 338 0.0027 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 SUPERFAMILY SSF50129 3 172 1.73E-50 T 28-03-2018 IPR011032 GroES-like WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 Gene3D G3DSA:3.90.180.10 1 147 1.5E-45 T 28-03-2018 WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 132 7.7E-34 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS23945 9cae72c3f9eca653e43aaa6b0639ac7d 340 Pfam PF00107 Zinc-binding dehydrogenase 173 300 1.5E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS04085 67893de71f5aaa61d3e38952274db5f3 330 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 317 5.3E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS04085 67893de71f5aaa61d3e38952274db5f3 330 Gene3D G3DSA:1.10.3470.10 29 323 2.4E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 SMART SM00382 28 213 4.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 Pfam PF00005 ABC transporter 20 166 3.5E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 Gene3D G3DSA:3.40.50.300 1 236 4.5E-64 T 28-03-2018 WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 2.0E-7 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 3 241 9.8E-121 T 28-03-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 WM46_RS16930 3679baa45b7b19ef93cbff3dc552a482 241 SUPERFAMILY SSF52540 4 236 6.95E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 16 218 38.735 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 188 201 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 SUPERFAMILY SSF50475 21 218 7.3E-68 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 Gene3D G3DSA:2.30.110.10 17 218 1.4E-70 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 218 8.9E-102 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 122 3.6E-25 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 178 218 1.2E-18 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM46_RS07490 2f47655139bbaada5fb397ef9259eca7 218 PIRSF PIRSF000190 1 218 4.1E-86 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 SUPERFAMILY SSF109604 306 493 5.18E-47 T 28-03-2018 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 Gene3D G3DSA:3.30.420.150 120 298 6.2E-35 T 28-03-2018 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 Pfam PF02541 Ppx/GppA phosphatase family 20 300 5.8E-101 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 Hamap MF_01550 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [gppA]. 1 493 55.552 T 28-03-2018 IPR023709 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase GO:0008894|GO:0015974 KEGG: 00230+3.6.1.40 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 SUPERFAMILY SSF53067 131 299 1.48E-40 T 28-03-2018 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 PIRSF PIRSF001267 1 494 4.2E-186 T 28-03-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 Gene3D G3DSA:3.30.420.40 1 119 4.9E-40 T 28-03-2018 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 SUPERFAMILY SSF53067 6 127 3.63E-37 T 28-03-2018 WM46_RS19280 2cbbe29d4b624100515bb43935fb5892 494 Gene3D G3DSA:1.10.3210.10 322 484 7.5E-4 T 28-03-2018 WM46_RS07090 2012c255339ac9abfad485e182f88190 300 SUPERFAMILY SSF103481 202 288 2.75E-8 T 28-03-2018 WM46_RS07090 2012c255339ac9abfad485e182f88190 300 Pfam PF00892 EamA-like transporter family 143 286 4.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS07090 2012c255339ac9abfad485e182f88190 300 Pfam PF00892 EamA-like transporter family 7 130 1.5E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS07090 2012c255339ac9abfad485e182f88190 300 SUPERFAMILY SSF103481 40 134 8.37E-12 T 28-03-2018 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 214 337 2.4E-72 T 28-03-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 Gene3D G3DSA:1.10.8.60 143 222 2.3E-23 T 28-03-2018 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 SUPERFAMILY SSF52540 1 210 1.44E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 SUPERFAMILY SSF48019 212 334 3.83E-35 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 Gene3D G3DSA:1.20.272.10 223 343 1.5E-27 T 28-03-2018 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 Pfam PF06144 DNA polymerase III, delta subunit 21 190 1.7E-49 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 18 332 5.1E-108 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 WM46_RS11360 d3efd58b9172890599df7a92c276a5ef 343 Gene3D G3DSA:3.40.50.300 1 140 7.2E-20 T 28-03-2018 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 Pfam PF13378 Enolase C-terminal domain-like 135 355 7.3E-55 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 SUPERFAMILY SSF51604 95 357 3.14E-72 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 9.5E-31 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 SUPERFAMILY SSF54826 1 112 4.66E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 Hamap MF_01289 D-galactonate dehydratase [dgoD]. 1 382 76.53 T 28-03-2018 IPR023592 D-galactonate dehydratase GO:0008869|GO:0034194 KEGG: 00052+4.2.1.6 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 Gene3D G3DSA:3.20.20.120 98 346 6.5E-68 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 Gene3D G3DSA:3.30.390.10 347 382 0.0093 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 Gene3D G3DSA:3.30.390.10 1 97 1.4E-29 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS19690 6b559b74bdeaf683b23de944090d2feb 382 SMART SM00922 125 230 6.1E-18 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 50 375 7.4E-151 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 Pfam PF08402 TOBE domain 295 375 1.1E-20 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 Gene3D G3DSA:3.40.50.300 16 289 2.1E-77 T 28-03-2018 WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 SUPERFAMILY SSF52540 19 257 2.6E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 Pfam PF00005 ABC transporter 36 177 4.5E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 SMART SM00382 44 227 3.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 Gene3D G3DSA:2.40.50.140 298 368 2.0E-7 T 28-03-2018 WM46_RS10155 97a8fe73bf485d9330bb3c8d5e718a8e 377 SUPERFAMILY SSF50331 252 375 8.16E-18 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS24840 0b48a9e1f99ef82a0bed4c2f17b46097 72 Pfam PF06004 Bacterial protein of unknown function (DUF903) 23 71 3.3E-24 T 28-03-2018 IPR010305 Protein of unknown function DUF903 WM46_RS24840 0b48a9e1f99ef82a0bed4c2f17b46097 72 Gene3D G3DSA:2.30.30.100 21 71 2.2E-26 T 28-03-2018 WM46_RS24840 0b48a9e1f99ef82a0bed4c2f17b46097 72 SUPERFAMILY SSF50182 21 71 3.11E-18 T 28-03-2018 IPR010920 LSM domain WM46_RS24615 d4847188300f78b198dff2ea779e4439 179 Pfam PF00419 Fimbrial protein 34 179 3.8E-21 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24615 d4847188300f78b198dff2ea779e4439 179 SUPERFAMILY SSF49401 31 179 7.46E-35 T 28-03-2018 IPR008966 Adhesion domain WM46_RS24615 d4847188300f78b198dff2ea779e4439 179 Gene3D G3DSA:2.60.40.1090 30 179 6.7E-33 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS23230 8cf9e3ab476d134ce0bf677ce3f8c014 372 Pfam PF03841 L-seryl-tRNA selenium transferase 14 322 8.8E-15 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 WM46_RS23230 8cf9e3ab476d134ce0bf677ce3f8c014 372 Gene3D G3DSA:3.40.640.10 42 247 2.8E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS23230 8cf9e3ab476d134ce0bf677ce3f8c014 372 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 4 365 3.2E-183 T 28-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 WM46_RS23230 8cf9e3ab476d134ce0bf677ce3f8c014 372 SUPERFAMILY SSF53383 6 367 1.32E-33 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 SUPERFAMILY SSF51735 5 263 3.29E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 1.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 263 2.2E-31 T 28-03-2018 WM46_RS10205 5654a4a53ecc471a23a0ce28151df657 265 Gene3D G3DSA:3.40.50.720 1 264 1.1E-42 T 28-03-2018 WM46_RS20980 594a8b0fc7df94f87cc47b4d95642e39 577 Pfam PF00884 Sulfatase 238 529 1.5E-43 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS20980 594a8b0fc7df94f87cc47b4d95642e39 577 SUPERFAMILY SSF53649 236 554 2.43E-29 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS20980 594a8b0fc7df94f87cc47b4d95642e39 577 Pfam PF08019 Domain of unknown function (DUF1705) 61 164 1.5E-4 T 28-03-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 WM46_RS20980 594a8b0fc7df94f87cc47b4d95642e39 577 Gene3D G3DSA:3.40.720.10 231 534 2.6E-21 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS08550 1012401e1cb51dbc21fdf039971d519e 233 Pfam PF00005 ABC transporter 25 173 5.1E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS08550 1012401e1cb51dbc21fdf039971d519e 233 SMART SM00382 34 222 9.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS08550 1012401e1cb51dbc21fdf039971d519e 233 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 5 224 9.7E-112 T 28-03-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 WM46_RS08550 1012401e1cb51dbc21fdf039971d519e 233 Gene3D G3DSA:3.40.50.300 1 231 1.1E-66 T 28-03-2018 WM46_RS08550 1012401e1cb51dbc21fdf039971d519e 233 SUPERFAMILY SSF52540 5 224 1.56E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08550 1012401e1cb51dbc21fdf039971d519e 233 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS24655 bf8ca6d3fd13133f1d263d846384f421 363 Pfam PF00419 Fimbrial protein 213 362 1.7E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24655 bf8ca6d3fd13133f1d263d846384f421 363 Gene3D G3DSA:2.60.40.1090 213 363 7.5E-24 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24655 bf8ca6d3fd13133f1d263d846384f421 363 SUPERFAMILY SSF49401 214 363 4.42E-20 T 28-03-2018 IPR008966 Adhesion domain WM46_RS08830 b84b776badc1c4f92353ccbf5e99e375 194 Pfam PF13302 Acetyltransferase (GNAT) domain 17 162 1.1E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS08830 b84b776badc1c4f92353ccbf5e99e375 194 SUPERFAMILY SSF55729 12 185 6.23E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS08830 b84b776badc1c4f92353ccbf5e99e375 194 Gene3D G3DSA:3.40.630.30 1 194 1.3E-31 T 28-03-2018 WM46_RS00220 342f85d24331467f510e0aec4dabbdc3 407 SMART SM00267 237 407 1.6E-52 T 28-03-2018 IPR000160 GGDEF domain WM46_RS00220 342f85d24331467f510e0aec4dabbdc3 407 SUPERFAMILY SSF55073 253 403 2.43E-35 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS00220 342f85d24331467f510e0aec4dabbdc3 407 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 246 404 4.2E-33 T 28-03-2018 IPR000160 GGDEF domain WM46_RS00220 342f85d24331467f510e0aec4dabbdc3 407 Pfam PF00990 Diguanylate cyclase, GGDEF domain 248 403 8.5E-41 T 28-03-2018 IPR000160 GGDEF domain WM46_RS00220 342f85d24331467f510e0aec4dabbdc3 407 Gene3D G3DSA:3.30.70.270 242 406 7.8E-46 T 28-03-2018 WM46_RS00220 342f85d24331467f510e0aec4dabbdc3 407 Pfam PF17152 Periplasmic sensor domain 44 144 1.8E-29 T 28-03-2018 IPR033417 Periplasmic sensor domain CHASE8 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 4.1E-98 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 SUPERFAMILY SSF54211 595 771 2.62E-59 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 201 1.8E-42 T 28-03-2018 IPR003111 Lon, substrate-binding domain WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 SUPERFAMILY SSF52540 313 587 3.71E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 SUPERFAMILY SSF88697 10 201 5.22E-52 T 28-03-2018 IPR015947 PUA-like domain WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 1.5E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 SMART SM00382 348 492 3.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Gene3D G3DSA:1.10.4060.10 122 211 2.1E-31 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 PIRSF PIRSF001174 1 775 0.0 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Gene3D G3DSA:2.30.130.40 1 118 2.1E-31 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Gene3D G3DSA:1.10.8.60 491 584 4.7E-33 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Hamap MF_01973 Lon protease [lon]. 11 772 72.512 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 SMART SM00464 10 202 2.8E-87 T 28-03-2018 IPR003111 Lon, substrate-binding domain WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Gene3D G3DSA:3.30.230.10 585 772 3.0E-70 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 Gene3D G3DSA:3.40.50.300 313 490 4.6E-30 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 2.5E-57 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 2.5E-57 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 2.5E-57 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 2.5E-57 T 28-03-2018 WM46_RS12620 b3a7f4ca5fedad3556f1d9ff056f76fe 784 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 2.5E-57 T 28-03-2018 WM46_RS14570 cd5adea487d459a0142ae6d388d1b790 125 SUPERFAMILY SSF110069 5 125 5.89E-47 T 28-03-2018 IPR007474 ApaG domain WM46_RS14570 cd5adea487d459a0142ae6d388d1b790 125 Hamap MF_00791 Protein ApaG [apaG]. 1 125 32.659 T 28-03-2018 IPR023065 Uncharacterised protein family ApaG WM46_RS14570 cd5adea487d459a0142ae6d388d1b790 125 Gene3D G3DSA:2.60.40.1470 3 125 2.7E-41 T 28-03-2018 IPR007474 ApaG domain WM46_RS14570 cd5adea487d459a0142ae6d388d1b790 125 Pfam PF04379 ApaG domain 18 102 4.5E-33 T 28-03-2018 IPR007474 ApaG domain WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 SUPERFAMILY SSF56935 38 757 4.12E-137 T 28-03-2018 WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 45 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 Pfam PF00593 TonB dependent receptor 281 754 1.4E-59 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 54 757 2.1E-141 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 Gene3D G3DSA:2.170.130.10 45 180 4.9E-36 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 Pfam PF07715 TonB-dependent Receptor Plug Domain 53 167 3.4E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 Gene3D G3DSA:2.40.170.20 181 757 2.0E-81 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS11640 ddb0e635b7db9f7237565046a009aaf0 757 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 740 757 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS23715 257e7650f8e62377e134c4b5735a9014 290 Pfam PF13391 HNH endonuclease 182 235 2.2E-6 T 28-03-2018 IPR003615 HNH nuclease WM46_RS23715 257e7650f8e62377e134c4b5735a9014 290 PIRSF PIRSF030850 1 290 1.3E-131 T 28-03-2018 IPR011396 Uncharacterised conserved protein UCP030850 WM46_RS23715 257e7650f8e62377e134c4b5735a9014 290 Gene3D G3DSA:3.40.1800.10 161 241 9.5E-9 T 28-03-2018 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 152 163 4.0E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 114 133 4.0E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 Gene3D G3DSA:2.10.240.10 235 266 6.6E-9 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 PRINTS PR00410 Phenol hydroxylase reductase family signature 114 133 2.6E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 PRINTS PR00410 Phenol hydroxylase reductase family signature 203 211 2.6E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 PRINTS PR00410 Phenol hydroxylase reductase family signature 42 54 2.6E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 TIGRFAM TIGR02911 sulfite_red_B: sulfite reductase, subunit B 12 272 1.1E-134 T 28-03-2018 IPR014260 Sulphite reductase, subunit B WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 Gene3D G3DSA:3.40.50.80 94 232 1.0E-20 T 28-03-2018 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 Pfam PF00175 Oxidoreductase NAD-binding domain 116 216 3.6E-19 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 SUPERFAMILY SSF63380 16 103 1.28E-16 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 SUPERFAMILY SSF52343 110 250 1.57E-29 T 28-03-2018 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 Gene3D G3DSA:2.40.30.10 16 93 1.1E-8 T 28-03-2018 WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 235 264 3.5E-8 T 28-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain WM46_RS00595 4f018f054a538a5afd61e4647741ac48 272 PIRSF PIRSF006816 13 271 1.2E-78 T 28-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 Pfam PF01642 Methylmalonyl-CoA mutase 28 539 4.5E-234 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 Gene3D G3DSA:3.20.20.240 27 542 2.7E-240 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 28 547 1.1E-276 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 SUPERFAMILY SSF52242 555 713 1.01E-55 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 SUPERFAMILY SSF51703 4 542 4.45E-218 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 583 713 1.2E-65 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 Pfam PF02310 B12 binding domain 586 701 2.6E-16 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 Gene3D G3DSA:3.40.50.280 567 714 1.1E-36 T 28-03-2018 WM46_RS10670 c6432d0fa5f19d2cd22aa72364b0377c 714 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 370 395 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS06665 2f089e0f29be9c46491cdb5e3f4be6a0 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 17 80 5.4E-8 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS06665 2f089e0f29be9c46491cdb5e3f4be6a0 205 Gene3D G3DSA:3.40.30.10 1 101 7.1E-14 T 28-03-2018 WM46_RS06665 2f089e0f29be9c46491cdb5e3f4be6a0 205 SUPERFAMILY SSF52833 2 79 2.55E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS06665 2f089e0f29be9c46491cdb5e3f4be6a0 205 SUPERFAMILY SSF47616 79 201 1.08E-15 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS06665 2f089e0f29be9c46491cdb5e3f4be6a0 205 Gene3D G3DSA:1.20.1050.10 102 205 1.1E-10 T 28-03-2018 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 Pfam PF00425 chorismate binding enzyme 190 443 5.6E-91 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 Gene3D G3DSA:3.60.120.10 1 453 4.5E-153 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 SUPERFAMILY SSF56322 4 451 5.49E-145 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 Pfam PF04715 Anthranilate synthase component I, N terminal region 20 153 9.6E-27 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 107 447 1.3E-130 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 PRINTS PR00095 Anthranilate synthase component I signature 291 304 8.2E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 PRINTS PR00095 Anthranilate synthase component I signature 305 318 8.2E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 PRINTS PR00095 Anthranilate synthase component I signature 385 399 8.2E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS04990 8ec5e2652db367d926969af9ceb8bc9e 453 PRINTS PR00095 Anthranilate synthase component I signature 400 414 8.2E-18 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 SUPERFAMILY SSF52540 582 645 4.7E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 SUPERFAMILY SSF52540 680 712 4.7E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 SUPERFAMILY SSF52540 790 908 4.7E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 TIGRFAM TIGR02686 relax_trwC: conjugative relaxase domain 18 292 3.1E-86 T 28-03-2018 IPR014059 Conjugative relaxase, N-terminal WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 Pfam PF13538 UvrD-like helicase C-terminal domain 851 895 1.1E-8 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 SUPERFAMILY SSF55464 1 292 1.65E-88 T 28-03-2018 WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 SUPERFAMILY SSF52540 474 633 1.11E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 Pfam PF08751 TrwC relaxase 16 287 6.7E-80 T 28-03-2018 IPR014862 TrwC relaxase WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 Pfam PF13604 AAA domain 477 654 4.6E-42 T 28-03-2018 WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 Gene3D G3DSA:3.40.50.300 118 595 1.5E-8 T 28-03-2018 WM46_RS26150 732f8668e49868e454f8d8147d963476 1078 Gene3D G3DSA:3.40.50.300 596 913 4.7E-10 T 28-03-2018 WM46_RS04395 4774933d64997324e96a308b3e857be5 76 SUPERFAMILY SSF46575 1 75 2.22E-33 T 28-03-2018 WM46_RS04395 4774933d64997324e96a308b3e857be5 76 Gene3D G3DSA:1.20.58.250 3 65 1.1E-29 T 28-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS04395 4774933d64997324e96a308b3e857be5 76 Pfam PF06440 DNA polymerase III, theta subunit 4 71 2.5E-37 T 28-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS04395 4774933d64997324e96a308b3e857be5 76 ProDom PD057609 DNA POLYMERASE THETA SUBUNIT TRANSFERASE III NUCLEOTIDYLTRANSFERASE III DNA-DIRECTED REPLICATION 1 76 8.0E-34 T 28-03-2018 IPR009052 DNA polymerase III-theta, bacterial GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 TIGRFAM TIGR01089 fucI: L-fucose isomerase 5 590 0.0 T 28-03-2018 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Gene3D G3DSA:3.40.275.10 177 339 4.1E-63 T 28-03-2018 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Pfam PF07882 L-fucose isomerase, second N-terminal domain 175 354 3.4E-82 T 28-03-2018 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 SUPERFAMILY SSF53743 2 355 7.06E-153 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Hamap MF_01254 L-fucose isomerase [fucI]. 3 591 71.343 T 28-03-2018 IPR005763 L-fucose isomerase GO:0005737|GO:0008736|GO:0019317|GO:0030145 KEGG: 00051+5.3.1.25 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Gene3D G3DSA:3.40.50.1070 5 175 3.9E-70 T 28-03-2018 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 SUPERFAMILY SSF50443 356 590 4.18E-128 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Pfam PF07881 L-fucose isomerase, first N-terminal domain 7 174 8.8E-83 T 28-03-2018 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Pfam PF02952 L-fucose isomerase, C-terminal domain 390 554 1.2E-54 T 28-03-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 WM46_RS25005 c475c0d83e8f83a119ea5cbce3965c4c 591 Gene3D G3DSA:3.20.14.10 341 589 3.2E-119 T 28-03-2018 WM46_RS10090 491fcf54ea10ea95e6f520bbf9c6614e 337 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 234 3.8E-27 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS10090 491fcf54ea10ea95e6f520bbf9c6614e 337 Gene3D G3DSA:3.90.25.10 181 337 1.4E-25 T 28-03-2018 WM46_RS10090 491fcf54ea10ea95e6f520bbf9c6614e 337 Gene3D G3DSA:3.40.50.720 1 180 6.1E-27 T 28-03-2018 WM46_RS10090 491fcf54ea10ea95e6f520bbf9c6614e 337 SUPERFAMILY SSF51735 298 335 6.24E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS10090 491fcf54ea10ea95e6f520bbf9c6614e 337 SUPERFAMILY SSF51735 1 270 6.24E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS16375 9e322225619a3ebf5faa68827f23efd9 332 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 8.7E-27 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS16375 9e322225619a3ebf5faa68827f23efd9 332 Gene3D G3DSA:3.40.50.720 1 147 3.4E-35 T 28-03-2018 WM46_RS16375 9e322225619a3ebf5faa68827f23efd9 332 SUPERFAMILY SSF55347 127 290 1.8E-22 T 28-03-2018 WM46_RS16375 9e322225619a3ebf5faa68827f23efd9 332 SUPERFAMILY SSF51735 2 152 5.31E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS16375 9e322225619a3ebf5faa68827f23efd9 332 Gene3D G3DSA:3.30.360.10 148 325 6.1E-27 T 28-03-2018 WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Pfam PF07732 Multicopper oxidase 52 166 1.2E-26 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 SUPERFAMILY SSF49503 3 165 4.67E-25 T 28-03-2018 IPR008972 Cupredoxin WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Gene3D G3DSA:2.60.40.420 346 470 5.4E-17 T 28-03-2018 IPR008972 Cupredoxin WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Pfam PF07731 Multicopper oxidase 358 469 2.3E-14 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Pfam PF00394 Multicopper oxidase 228 287 3.2E-4 T 28-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 SUPERFAMILY SSF49503 314 466 3.41E-21 T 28-03-2018 IPR008972 Cupredoxin WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Gene3D G3DSA:2.60.40.420 28 164 4.4E-22 T 28-03-2018 IPR008972 Cupredoxin WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Hamap MF_00915 Cell division protein FtsP [ftsP]. 1 467 58.283 T 28-03-2018 IPR026589 Cell division protein FtsP GO:0043093 WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 SUPERFAMILY SSF49503 172 310 9.21E-30 T 28-03-2018 IPR008972 Cupredoxin WM46_RS16040 6294e6acb4ac7cd0cd7e140cc3b478d5 470 Gene3D G3DSA:2.60.40.420 167 298 9.7E-25 T 28-03-2018 IPR008972 Cupredoxin WM46_RS24445 8c34f3efd990a5d28bacdb7da608b848 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 281 1.6E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS24445 8c34f3efd990a5d28bacdb7da608b848 295 SUPERFAMILY SSF161098 27 295 5.49E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS24445 8c34f3efd990a5d28bacdb7da608b848 295 Gene3D G3DSA:1.10.3720.10 21 283 3.2E-34 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 449 1.0E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.4E-28 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.4E-28 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.4E-28 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.4E-28 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.4E-28 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 SUPERFAMILY SSF51905 1 365 8.2E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 1.1E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 450 3.9E-218 T 28-03-2018 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081|Reactome: R-HSA-2408550|Reactome: R-HSA-3299685|Reactome: R-HSA-499943|Reactome: R-HSA-5628897 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.2E-66 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 Gene3D G3DSA:3.40.50.720 164 331 2.0E-35 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 Gene3D G3DSA:3.30.390.30 332 450 1.4E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 Gene3D G3DSA:3.50.50.60 1 163 1.3E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 PIRSF PIRSF000350 1 447 3.0E-87 T 28-03-2018 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 WM46_RS20765 c7532079aef76be090ef5a9a9d7bc8eb 450 SUPERFAMILY SSF55424 336 450 6.7E-37 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 Pfam PF00501 AMP-binding enzyme 51 482 2.0E-111 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 Gene3D G3DSA:2.30.38.10 394 475 2.7E-28 T 28-03-2018 WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 Gene3D G3DSA:3.40.50.980 239 393 2.1E-38 T 28-03-2018 WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 ProSitePatterns PS00455 Putative AMP-binding domain signature. 233 244 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 Gene3D G3DSA:3.40.50.980 42 238 3.0E-42 T 28-03-2018 WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 Pfam PF13193 AMP-binding enzyme C-terminal domain 491 565 2.9E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 Gene3D G3DSA:3.30.300.30 477 582 8.8E-28 T 28-03-2018 WM46_RS05020 5205d7a3582d92fb3e373ca7ed0d7e5a 583 SUPERFAMILY SSF56801 34 577 1.07E-152 T 28-03-2018 WM46_RS13835 90f13627755b305f8e7f092d00e77400 134 Pfam PF16358 RcsF lipoprotein 28 132 4.9E-50 T 28-03-2018 IPR030852 Outer membrane lipoprotein RcsF GO:0009279|GO:0035556 WM46_RS13835 90f13627755b305f8e7f092d00e77400 134 Hamap MF_00976 Outer membrane lipoprotein RcsF [rcsF]. 1 133 35.783 T 28-03-2018 IPR030852 Outer membrane lipoprotein RcsF GO:0009279|GO:0035556 WM46_RS04400 83db26fe56dfec2a30e40d910ab7bd1d 124 SUPERFAMILY SSF81296 26 124 1.26E-26 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS04400 83db26fe56dfec2a30e40d910ab7bd1d 124 Gene3D G3DSA:2.60.40.1220 26 124 3.1E-31 T 28-03-2018 WM46_RS04400 83db26fe56dfec2a30e40d910ab7bd1d 124 Pfam PF04234 CopC domain 27 123 1.9E-26 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 WM46_RS18515 68200d9d93809737a25263dd5c89808f 166 PIRSF PIRSF034445 2 146 6.7E-30 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 WM46_RS18515 68200d9d93809737a25263dd5c89808f 166 Pfam PF07813 LTXXQ motif family protein 42 135 4.7E-22 T 28-03-2018 IPR012899 LTXXQ motif family protein GO:0042597 WM46_RS16325 dfec3e492c37ccbb5c3b8eb3d179979f 112 SUPERFAMILY SSF140670 11 107 5.23E-49 T 28-03-2018 WM46_RS16325 dfec3e492c37ccbb5c3b8eb3d179979f 112 Pfam PF08986 Domain of unknown function (DUF1889) 1 107 2.7E-51 T 28-03-2018 IPR015079 Protein of unknown function DUF1889 WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 Gene3D G3DSA:3.30.360.10 129 338 2.1E-25 T 28-03-2018 WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 SUPERFAMILY SSF55347 127 279 2.18E-16 T 28-03-2018 WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 112 9.8E-13 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 SUPERFAMILY SSF51735 170 187 1.87E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 SUPERFAMILY SSF51735 1 142 1.87E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 192 3.8E-5 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS22330 6fa47517f3d945d132db2fde3297eafd 338 Gene3D G3DSA:3.40.50.720 1 128 2.3E-18 T 28-03-2018 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 SUPERFAMILY SSF63380 3 97 1.97E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 Pfam PF00175 Oxidoreductase NAD-binding domain 108 211 5.8E-23 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 Pfam PF00970 Oxidoreductase FAD-binding domain 6 95 1.1E-6 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 Gene3D G3DSA:3.40.50.80 99 233 5.7E-25 T 28-03-2018 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 SUPERFAMILY SSF52343 100 231 6.94E-36 T 28-03-2018 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 2.0E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 91 100 2.0E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 107 126 2.0E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 141 2.0E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 PRINTS PR00410 Phenol hydroxylase reductase family signature 47 54 2.0E-13 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 WM46_RS18970 bf043bfe1e4200d7960717ddc684fba2 233 Gene3D G3DSA:2.40.30.10 2 98 3.5E-18 T 28-03-2018 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 Pfam PF04055 Radical SAM superfamily 380 585 1.0E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 29 644 2.5E-265 T 28-03-2018 IPR022946 Uncharacterised protein family UPF0313 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 29 646 50.83 T 28-03-2018 IPR022946 Uncharacterised protein family UPF0313 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 380 400 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 Gene3D G3DSA:3.20.20.70 303 722 9.3E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 SUPERFAMILY SSF102114 361 440 5.49E-11 T 28-03-2018 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 SUPERFAMILY SSF102114 470 624 5.49E-11 T 28-03-2018 WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 Pfam PF11842 Domain of unknown function (DUF3362) 594 717 4.0E-44 T 28-03-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 Pfam PF08497 Radical SAM N-terminal 29 379 1.0E-145 T 28-03-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal WM46_RS16035 f3b5f1b7696ef5cf095e1ff1e12bd79a 723 SMART SM00729 376 626 4.7E-5 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 Pfam PF02167 Cytochrome C1 family 32 263 4.4E-69 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 Gene3D G3DSA:1.10.760.10 21 232 1.7E-49 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 SUPERFAMILY SSF46626 26 230 4.88E-42 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 50 69 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 97 117 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 130 154 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 232 247 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 30 49 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 180 191 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 PRINTS PR00603 Cytochrome C1 signature 213 232 2.3E-37 T 28-03-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 WM46_RS05485 455295c82ad9eda18f4e745aab108d58 267 Gene3D G3DSA:1.20.5.100 236 260 2.4E-4 T 28-03-2018 WM46_RS07035 057b6cffe869035110008f9d92c38099 478 Gene3D G3DSA:3.30.70.270 296 467 1.3E-43 T 28-03-2018 WM46_RS07035 057b6cffe869035110008f9d92c38099 478 SMART SM00267 292 465 7.8E-52 T 28-03-2018 IPR000160 GGDEF domain WM46_RS07035 057b6cffe869035110008f9d92c38099 478 Pfam PF00990 Diguanylate cyclase, GGDEF domain 303 461 1.0E-40 T 28-03-2018 IPR000160 GGDEF domain WM46_RS07035 057b6cffe869035110008f9d92c38099 478 SUPERFAMILY SSF55073 308 462 8.63E-38 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS07035 057b6cffe869035110008f9d92c38099 478 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 303 462 5.1E-37 T 28-03-2018 IPR000160 GGDEF domain WM46_RS07825 d397fff76c012d3d1b399986e11797d0 138 Hamap MF_01832 Cysteine desulfuration protein SufE [sufE]. 1 138 41.573 T 28-03-2018 IPR023939 Cysteine desulfuration protein SufE GO:0006790|GO:0016226 WM46_RS07825 d397fff76c012d3d1b399986e11797d0 138 SUPERFAMILY SSF82649 3 135 4.92E-44 T 28-03-2018 WM46_RS07825 d397fff76c012d3d1b399986e11797d0 138 Pfam PF02657 Fe-S metabolism associated domain 12 132 3.6E-42 T 28-03-2018 IPR003808 Fe-S metabolism associated domain, SufE-like WM46_RS07825 d397fff76c012d3d1b399986e11797d0 138 Gene3D G3DSA:3.90.1010.10 1 137 6.1E-47 T 28-03-2018 WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 Gene3D G3DSA:3.40.50.1100 148 327 1.5E-26 T 28-03-2018 WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 PIRSF PIRSF006278 2 328 3.1E-93 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 316 3.2E-53 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 Gene3D G3DSA:3.40.50.1100 50 147 4.6E-30 T 28-03-2018 WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 Hamap MF_01045 D-cysteine desulfhydrase [dcyD]. 1 328 76.747 T 28-03-2018 IPR023702 D-cysteine desulphhydrase, bacterial GO:0019148 KEGG: 00270+4.4.1.15 WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 SUPERFAMILY SSF53686 7 326 2.62E-85 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS03900 fbd2e570bc8fc77e81ade208ac2e27bd 328 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 12 328 1.4E-141 T 28-03-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 WM46_RS12040 c472df7a01ce8cc1dab7426cd6ee0e5e 209 SUPERFAMILY SSF51206 16 128 1.57E-7 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like WM46_RS12040 c472df7a01ce8cc1dab7426cd6ee0e5e 209 Pfam PF15977 Winged helix-turn-helix DNA binding 140 206 9.5E-26 T 28-03-2018 WM46_RS12040 c472df7a01ce8cc1dab7426cd6ee0e5e 209 Gene3D G3DSA:2.60.120.10 12 113 6.0E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS12040 c472df7a01ce8cc1dab7426cd6ee0e5e 209 Gene3D G3DSA:1.10.10.10 133 208 2.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 Gene3D G3DSA:1.10.540.10 1 115 1.3E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 3.0E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 7.3E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 SUPERFAMILY SSF47203 226 381 1.01E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 Gene3D G3DSA:2.40.110.10 120 217 3.5E-28 T 28-03-2018 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 107 8.7E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 PIRSF PIRSF016578 10 95 0.0011 T 28-03-2018 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 PIRSF PIRSF016578 134 191 0.54 T 28-03-2018 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 PIRSF PIRSF016578 235 381 1.6E-10 T 28-03-2018 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 Gene3D G3DSA:1.20.140.10 218 383 3.9E-53 T 28-03-2018 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 SUPERFAMILY SSF56645 1 228 3.53E-51 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 WM46_RS07920 7d0e04134550da931f1cfe3fde195086 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 SUPERFAMILY SSF46557 3 78 4.71E-28 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 154 29.003 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 Hamap MF_00930 Transcription elongation factor GreB [greB]. 1 156 54.361 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.0E-26 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 Gene3D G3DSA:1.10.287.180 3 75 2.9E-29 T 28-03-2018 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 Gene3D G3DSA:3.10.50.30 76 157 1.3E-22 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 PIRSF PIRSF006092 1 157 9.7E-47 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 SUPERFAMILY SSF54534 80 155 5.23E-21 T 28-03-2018 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 2 157 3.2E-87 T 28-03-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 1.7E-23 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 WM46_RS17860 643ad03d814e4e2013a064a5fdb8159c 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 SUPERFAMILY SSF46894 121 188 2.86E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 SMART SM00421 127 184 7.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 Gene3D G3DSA:1.10.10.10 127 188 1.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 130 144 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 160 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 172 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11830 4126971b67579334e32b32ac7e771af5 195 Pfam PF00196 Bacterial regulatory proteins, luxR family 129 180 3.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Gene3D G3DSA:1.25.40.10 946 1013 3.8E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Gene3D G3DSA:1.25.40.10 877 945 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SUPERFAMILY SSF48452 894 1004 7.59E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SUPERFAMILY SSF48452 740 815 7.59E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Pfam PF13432 Tetratricopeptide repeat 573 626 0.011 T 28-03-2018 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Gene3D G3DSA:1.25.40.10 521 620 1.7E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Gene3D G3DSA:1.25.40.10 621 816 9.2E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Pfam PF17128 Domain of unknown function (DUF5107) 40 344 5.0E-63 T 28-03-2018 IPR033396 Domain of unknown function DUF5107 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 Gene3D G3DSA:1.25.40.10 457 520 5.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SMART SM00028 568 601 44.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SMART SM00028 932 965 270.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SMART SM00028 741 774 0.047 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SMART SM00028 775 809 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS00525 0fc540397bd5bb6c37ffd75355da3729 1088 SUPERFAMILY SSF48452 482 627 3.64E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS04950 71cc8d43f816d9e9185b6f5aa00ab966 283 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 12 281 8.4E-113 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS04950 71cc8d43f816d9e9185b6f5aa00ab966 283 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 11 281 5.1E-148 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS05400 963df8625a9e720d37c54b152984b55b 150 Gene3D G3DSA:3.40.140.10 26 150 1.6E-46 T 28-03-2018 WM46_RS05400 963df8625a9e720d37c54b152984b55b 150 Pfam PF04002 RadC-like JAB domain 31 149 1.4E-44 T 28-03-2018 IPR025657 RadC-like JAB domain WM46_RS05400 963df8625a9e720d37c54b152984b55b 150 TIGRFAM TIGR00608 radc: DNA repair protein RadC 23 149 3.4E-44 T 28-03-2018 IPR001405 RadC protein WM46_RS05400 963df8625a9e720d37c54b152984b55b 150 SUPERFAMILY SSF102712 71 120 4.84E-6 T 28-03-2018 WM46_RS05400 963df8625a9e720d37c54b152984b55b 150 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 99 104 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site WM46_RS22505 f7f1503a99cb2533ba41c49af10d19bd 302 Pfam PF04393 Protein of unknown function (DUF535) 23 298 5.5E-79 T 28-03-2018 IPR007488 Protein of unknown function DUF535 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 6.6E-70 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 455 1.2E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 SUPERFAMILY SSF55424 343 466 4.47E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 Gene3D G3DSA:3.50.50.60 238 334 7.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 Gene3D G3DSA:3.50.50.60 118 237 1.5E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PIRSF PIRSF000350 1 469 8.7E-88 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 SUPERFAMILY SSF51905 2 337 7.41E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 1.0E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 7 460 2.7E-150 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 Gene3D G3DSA:3.30.390.30 335 462 9.2E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.8E-41 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 3.8E-41 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 3.8E-41 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 3.8E-41 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 3.8E-41 T 28-03-2018 WM46_RS14250 119955be5a56b3d53b6e9d2dbd2816a2 475 Gene3D G3DSA:1.10.287.990 39 107 2.9E-20 T 28-03-2018 WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 15 281 9.1E-94 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 Gene3D G3DSA:1.20.140.10 292 494 3.1E-65 T 28-03-2018 WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 PIRSF PIRSF500125 1 518 2.5E-287 T 28-03-2018 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 SUPERFAMILY SSF47203 272 494 6.91E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 PIRSF PIRSF000331 11 501 1.1E-202 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 288 489 2.9E-64 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 SUPERFAMILY SSF56645 13 282 2.44E-83 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 TIGRFAM TIGR02310 HpaB-2: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 2 520 0.0 T 28-03-2018 IPR012688 4-HPA 3-monooxygenase large component, gammaproteobacteria GO:0010124|GO:0016712|GO:0050660 WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 Gene3D G3DSA:2.40.110.10 152 283 3.0E-13 T 28-03-2018 WM46_RS13380 60b5c3cde393b2ddef0b6fe6beacbf86 520 Gene3D G3DSA:1.10.3140.10 14 151 3.7E-52 T 28-03-2018 WM46_RS05125 d49939259132fca6bed0a848679ded30 270 SUPERFAMILY SSF52540 1 268 3.22E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05125 d49939259132fca6bed0a848679ded30 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 4.6E-110 T 28-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 WM46_RS05125 d49939259132fca6bed0a848679ded30 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 227 6.5E-20 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain WM46_RS05125 d49939259132fca6bed0a848679ded30 270 PIRSF PIRSF003092 1 270 1.4E-99 T 28-03-2018 IPR025501 ATP binding protein MinD WM46_RS05125 d49939259132fca6bed0a848679ded30 270 Gene3D G3DSA:3.40.50.300 1 259 2.3E-54 T 28-03-2018 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 SUPERFAMILY SSF56931 40 288 1.83E-91 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 Pfam PF02253 Phospholipase A1 44 285 2.4E-89 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 Gene3D G3DSA:2.40.230.10 33 289 2.4E-95 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 81 98 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 126 145 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 103 119 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 171 189 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 236 253 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 203 221 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 258 278 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS19075 71c4ef139461781701ca249608c65c76 289 PRINTS PR01486 Bacterial phospholipase A1 protein signature 156 170 5.6E-87 T 28-03-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 Gene3D G3DSA:3.40.50.720 3 172 6.7E-33 T 28-03-2018 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 Gene3D G3DSA:1.10.1040.10 173 294 3.9E-33 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 285 3.4E-36 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 PIRSF PIRSF000103 1 295 2.6E-81 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 163 9.4E-50 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 SUPERFAMILY SSF48179 164 294 4.53E-38 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 SUPERFAMILY SSF51735 5 164 1.45E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23520 53b1618f89901447dcfd60a6a9f61070 297 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 WM46_RS16235 745f7af14c88c70c260310cf7609fb69 205 SMART SM01207 10 185 6.1E-85 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM46_RS16235 745f7af14c88c70c260310cf7609fb69 205 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 195 4.8E-82 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM46_RS16235 745f7af14c88c70c260310cf7609fb69 205 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 7 193 18.385 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM46_RS16235 745f7af14c88c70c260310cf7609fb69 205 Pfam PF02660 Glycerol-3-phosphate acyltransferase 11 184 1.8E-49 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 WM46_RS21920 002c06fc2d86d2c55350ac44a7c6c9e8 332 Pfam PF03812 2-keto-3-deoxygluconate permease 3 312 3.6E-115 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS21920 002c06fc2d86d2c55350ac44a7c6c9e8 332 TIGRFAM TIGR00793 kdgT: 2-keto-3-deoxygluconate transporter 1 312 1.7E-160 T 28-03-2018 IPR018395 2-keto-3-deoxygluconate permease, subgroup GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS21920 002c06fc2d86d2c55350ac44a7c6c9e8 332 Hamap MF_00070 2-keto-3-deoxygluconate permease [kdgT]. 1 318 36.332 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS21920 002c06fc2d86d2c55350ac44a7c6c9e8 332 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 23 312 5.0E-84 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS12770 726e62e250bbd136faca4fd18d794103 156 SUPERFAMILY SSF52121 4 154 7.85E-59 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS12770 726e62e250bbd136faca4fd18d794103 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 150 3.3E-60 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS12770 726e62e250bbd136faca4fd18d794103 156 Gene3D G3DSA:3.40.50.960 1 155 1.2E-64 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS12770 726e62e250bbd136faca4fd18d794103 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.65 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS12770 726e62e250bbd136faca4fd18d794103 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 1.4E-55 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 WM46_RS09715 fdfec1486e7d8f6891b32a97f9534a3b 191 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 2 170 2.1E-72 T 28-03-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 WM46_RS09715 fdfec1486e7d8f6891b32a97f9534a3b 191 SUPERFAMILY SSF52218 1 141 4.5E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS09715 fdfec1486e7d8f6891b32a97f9534a3b 191 Pfam PF03358 NADPH-dependent FMN reductase 1 140 3.2E-35 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 WM46_RS09715 fdfec1486e7d8f6891b32a97f9534a3b 191 Gene3D G3DSA:3.40.50.360 1 185 3.6E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS02630 9841440eae7b13b56de243901c7f5bd8 369 ProSitePatterns PS01215 Mrp family signature. 213 229 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 WM46_RS02630 9841440eae7b13b56de243901c7f5bd8 369 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 106 349 5.3E-100 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 WM46_RS02630 9841440eae7b13b56de243901c7f5bd8 369 SUPERFAMILY SSF52540 108 355 3.86E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02630 9841440eae7b13b56de243901c7f5bd8 369 Hamap MF_02040 Iron-sulfur cluster carrier protein. 101 350 37.453 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein WM46_RS02630 9841440eae7b13b56de243901c7f5bd8 369 Gene3D G3DSA:3.40.50.300 92 328 2.5E-61 T 28-03-2018 WM46_RS02630 9841440eae7b13b56de243901c7f5bd8 369 SUPERFAMILY SSF117916 15 85 1.18E-5 T 28-03-2018 IPR034904 Fe-S cluster assembly domain WM46_RS08835 e8890110744498ba428132d8e92859d8 402 Hamap MF_01529 Multidrug resistance protein MdtH [mdtH]. 1 401 41.486 T 28-03-2018 IPR022855 Multidrug resistance protein MdtH WM46_RS08835 e8890110744498ba428132d8e92859d8 402 Gene3D G3DSA:1.20.1250.20 8 194 1.4E-26 T 28-03-2018 WM46_RS08835 e8890110744498ba428132d8e92859d8 402 Gene3D G3DSA:1.20.1250.20 197 401 2.3E-19 T 28-03-2018 WM46_RS08835 e8890110744498ba428132d8e92859d8 402 SUPERFAMILY SSF103473 13 391 1.57E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS08835 e8890110744498ba428132d8e92859d8 402 Pfam PF07690 Major Facilitator Superfamily 20 222 1.8E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS18490 03bf61dcc2f3b4302b0f17445a07560f 444 Gene3D G3DSA:1.20.1250.20 10 211 7.0E-17 T 28-03-2018 WM46_RS18490 03bf61dcc2f3b4302b0f17445a07560f 444 Pfam PF13347 MFS/sugar transport protein 10 428 7.8E-106 T 28-03-2018 WM46_RS18490 03bf61dcc2f3b4302b0f17445a07560f 444 SUPERFAMILY SSF103473 14 420 4.58E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS18490 03bf61dcc2f3b4302b0f17445a07560f 444 Gene3D G3DSA:1.20.1250.20 212 425 4.5E-14 T 28-03-2018 WM46_RS18490 03bf61dcc2f3b4302b0f17445a07560f 444 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 8 442 2.4E-111 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 SUPERFAMILY SSF54631 255 369 4.17E-16 T 28-03-2018 WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 Pfam PF00005 ABC transporter 22 168 9.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 SUPERFAMILY SSF52540 1 245 5.67E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 Pfam PF00571 CBS domain 257 307 2.3E-6 T 28-03-2018 IPR000644 CBS domain WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 SMART SM00382 31 218 6.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 Gene3D G3DSA:3.40.50.300 1 251 2.5E-72 T 28-03-2018 WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 SMART SM00116 263 311 2.4E-6 T 28-03-2018 IPR000644 CBS domain WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 20 367 2.2E-106 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 WM46_RS07250 d3366aa4257b6e40b14711d6154e58fc 382 Gene3D G3DSA:3.10.580.10 253 371 1.6E-13 T 28-03-2018 WM46_RS18220 cb9cb58d4eb46f2ad0061cd83dc38b59 185 Gene3D G3DSA:3.40.1000.10 43 185 1.4E-16 T 28-03-2018 WM46_RS18220 cb9cb58d4eb46f2ad0061cd83dc38b59 185 Pfam PF08786 DcrB 51 181 2.2E-30 T 28-03-2018 IPR014894 Protein DcrB WM46_RS15890 1fe8eeb52d57fa03b042e79df1fbed7f 619 SUPERFAMILY SSF56059 497 614 5.18E-75 T 28-03-2018 WM46_RS15890 1fe8eeb52d57fa03b042e79df1fbed7f 619 SUPERFAMILY SSF56059 210 379 5.18E-75 T 28-03-2018 WM46_RS15890 1fe8eeb52d57fa03b042e79df1fbed7f 619 SUPERFAMILY SSF54001 10 197 5.3E-60 T 28-03-2018 WM46_RS15890 1fe8eeb52d57fa03b042e79df1fbed7f 619 Pfam PF05257 CHAP domain 52 149 9.4E-12 T 28-03-2018 IPR007921 CHAP domain WM46_RS15890 1fe8eeb52d57fa03b042e79df1fbed7f 619 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 246 615 3.4E-66 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain WM46_RS15890 1fe8eeb52d57fa03b042e79df1fbed7f 619 SUPERFAMILY SSF52440 380 510 8.63E-39 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS04760 9f4aaf47b169354bd21d2c2098b98439 116 Pfam PF05939 Phage minor tail protein 4 109 3.5E-21 T 28-03-2018 IPR010265 Bacteriophage lambda, GpM, minor tail WM46_RS21490 e3542de65696d2ee71e2bd7d21b5e33e 261 Pfam PF10127 Predicted nucleotidyltransferase 10 256 3.0E-94 T 28-03-2018 IPR018775 Nucleotidyltransferase, predicted WM46_RS21490 e3542de65696d2ee71e2bd7d21b5e33e 261 Gene3D G3DSA:3.30.460.10 1 147 2.2E-6 T 28-03-2018 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 Gene3D G3DSA:3.40.50.720 7 187 7.8E-62 T 28-03-2018 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 SUPERFAMILY SSF55347 176 488 9.81E-113 T 28-03-2018 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 489 3.0E-205 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 SUPERFAMILY SSF51735 4 189 1.05E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 186 1.1E-57 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 176 182 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 166 194 7.2E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 218 235 7.2E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 142 155 7.2E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 327 353 7.2E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 236 252 7.2E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 Gene3D G3DSA:3.30.360.10 188 490 1.2E-125 T 28-03-2018 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 489 90.466 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 188 488 6.6E-116 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS04345 fc60db2a3370692c0d30043c97c35648 491 PIRSF PIRSF000110 1 491 4.4E-180 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 WM46_RS18895 daf56d4512dde41e64eba73dd614c5bb 328 Hamap MF_01497 Stress response kinase A [srkA]. 4 318 45.41 T 28-03-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 WM46_RS18895 daf56d4512dde41e64eba73dd614c5bb 328 Gene3D G3DSA:3.90.1200.10 110 323 3.7E-20 T 28-03-2018 WM46_RS18895 daf56d4512dde41e64eba73dd614c5bb 328 Gene3D G3DSA:3.30.200.20 5 107 1.3E-17 T 28-03-2018 WM46_RS18895 daf56d4512dde41e64eba73dd614c5bb 328 SUPERFAMILY SSF56112 6 327 4.67E-90 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS18895 daf56d4512dde41e64eba73dd614c5bb 328 Pfam PF01636 Phosphotransferase enzyme family 32 257 1.6E-41 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase WM46_RS12940 801c12376d39ec2ca80fc36651832109 303 Pfam PF04381 Putative exonuclease, RdgC 2 300 3.4E-126 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 WM46_RS12940 801c12376d39ec2ca80fc36651832109 303 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 2 302 43.085 T 28-03-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 WM46_RS16025 4805a3ffd126e8119342d74514598a51 387 Gene3D G3DSA:1.20.1090.10 184 387 1.7E-42 T 28-03-2018 WM46_RS16025 4805a3ffd126e8119342d74514598a51 387 SUPERFAMILY SSF56796 1 386 2.09E-107 T 28-03-2018 WM46_RS16025 4805a3ffd126e8119342d74514598a51 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS16025 4805a3ffd126e8119342d74514598a51 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS16025 4805a3ffd126e8119342d74514598a51 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 359 4.9E-92 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS16025 4805a3ffd126e8119342d74514598a51 387 Gene3D G3DSA:3.40.50.1970 9 183 5.1E-43 T 28-03-2018 WM46_RS16000 4cb2a9f0cd7549f8e8f52caa327475ef 244 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 11 222 6.1E-102 T 28-03-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 WM46_RS16000 4cb2a9f0cd7549f8e8f52caa327475ef 244 Pfam PF01618 MotA/TolQ/ExbB proton channel family 84 206 5.7E-35 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 TIGRFAM TIGR00433 bioB: biotin synthase 14 310 6.3E-125 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 220 310 2.0E-20 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 Pfam PF04055 Radical SAM superfamily 50 201 4.4E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 SMART SM00876 220 312 6.3E-48 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 PIRSF PIRSF001619 1 319 4.2E-140 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 Hamap MF_01694 Biotin synthase [bioB]. 5 313 41.783 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 SUPERFAMILY SSF102114 6 313 5.1E-95 T 28-03-2018 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 SMART SM00729 43 255 2.9E-41 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS10590 801799a7dbe4ed5e210c811c9045af6a 346 Gene3D G3DSA:3.20.20.70 4 315 1.4E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS05300 31e053f3cc510677f2bfb3c8546ced96 243 SUPERFAMILY SSF46955 4 84 1.05E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS05300 31e053f3cc510677f2bfb3c8546ced96 243 Gene3D G3DSA:1.10.1660.10 1 237 6.3E-25 T 28-03-2018 WM46_RS05300 31e053f3cc510677f2bfb3c8546ced96 243 SMART SM00422 4 73 4.0E-28 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS05300 31e053f3cc510677f2bfb3c8546ced96 243 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 30 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS05300 31e053f3cc510677f2bfb3c8546ced96 243 Pfam PF13411 MerR HTH family regulatory protein 4 72 1.3E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS02895 5248c73d1884acb9e508a7344cb09f47 331 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 221 3.3E-29 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS02895 5248c73d1884acb9e508a7344cb09f47 331 Gene3D G3DSA:3.40.50.720 1 316 4.8E-45 T 28-03-2018 WM46_RS02895 5248c73d1884acb9e508a7344cb09f47 331 SUPERFAMILY SSF51735 287 316 1.03E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02895 5248c73d1884acb9e508a7344cb09f47 331 SUPERFAMILY SSF51735 3 258 1.03E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23185 908ba448dd78282e183ff84b32248e96 450 Gene3D G3DSA:3.30.2290.10 10 236 4.0E-59 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain WM46_RS23185 908ba448dd78282e183ff84b32248e96 450 Pfam PF01523 Putative modulator of DNA gyrase 36 326 4.8E-60 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 WM46_RS23185 908ba448dd78282e183ff84b32248e96 450 SUPERFAMILY SSF111283 17 449 4.97E-131 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 WM46_RS08535 ecc01f500f96a8e429915a62dc5e3a1c 273 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 41 271 60.975 T 28-03-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 WM46_RS08535 ecc01f500f96a8e429915a62dc5e3a1c 273 Pfam PF02146 Sir2 family 48 221 4.5E-52 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 WM46_RS08535 ecc01f500f96a8e429915a62dc5e3a1c 273 Gene3D G3DSA:3.40.50.1220 31 272 3.9E-54 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS08535 ecc01f500f96a8e429915a62dc5e3a1c 273 SUPERFAMILY SSF52467 41 270 8.47E-75 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 1.9E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 1.9E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 1.9E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 1.9E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 1.9E-39 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 505 45.515 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 501 4.6E-82 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 SUPERFAMILY SSF55681 162 502 6.4E-123 T 28-03-2018 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 SUPERFAMILY SSF50249 14 155 5.14E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 Pfam PF01336 OB-fold nucleic acid binding domain 68 146 1.0E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 14 504 8.2E-238 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 Gene3D G3DSA:2.40.50.140 15 154 5.4E-41 T 28-03-2018 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 Gene3D G3DSA:3.30.930.10 156 501 2.4E-104 T 28-03-2018 WM46_RS24280 61045a019e09af3dd60e8c6bf21f81bf 505 PIRSF PIRSF039101 1 505 4.8E-205 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 WM46_RS07425 c1fd6b90763d021559631bdb4d0c19d9 71 Gene3D G3DSA:1.20.1280.40 1 70 2.8E-28 T 28-03-2018 IPR007985 Haemolysin expression modulating, HHA WM46_RS07425 c1fd6b90763d021559631bdb4d0c19d9 71 SUPERFAMILY SSF68989 1 71 3.53E-22 T 28-03-2018 IPR007985 Haemolysin expression modulating, HHA WM46_RS07425 c1fd6b90763d021559631bdb4d0c19d9 71 Pfam PF05321 Haemolysin expression modulating protein 8 68 1.6E-27 T 28-03-2018 IPR007985 Haemolysin expression modulating, HHA WM46_RS06530 cd6bbf4ee0b899901806a611d3ee5657 336 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 325 3.6E-98 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM46_RS06530 cd6bbf4ee0b899901806a611d3ee5657 336 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 330 3.4E-49 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM46_RS06530 cd6bbf4ee0b899901806a611d3ee5657 336 PIRSF PIRSF000267 2 336 5.0E-89 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 WM46_RS07635 e9f9187bc8bed973c5058be0d79c4f0f 401 SUPERFAMILY SSF103473 7 375 2.35E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07635 e9f9187bc8bed973c5058be0d79c4f0f 401 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 4 377 6.3E-135 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 WM46_RS07635 e9f9187bc8bed973c5058be0d79c4f0f 401 Pfam PF07690 Major Facilitator Superfamily 14 341 1.2E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07635 e9f9187bc8bed973c5058be0d79c4f0f 401 Gene3D G3DSA:1.20.1250.20 194 378 3.3E-11 T 28-03-2018 WM46_RS07635 e9f9187bc8bed973c5058be0d79c4f0f 401 Gene3D G3DSA:1.20.1250.20 6 193 1.2E-30 T 28-03-2018 WM46_RS06600 d3eac7286f3d4bd0389cd85cefc7bead 993 Pfam PF07520 Virulence factor SrfB 1 990 0.0 T 28-03-2018 IPR009216 Virulence factor SrfB WM46_RS06600 d3eac7286f3d4bd0389cd85cefc7bead 993 Gene3D G3DSA:3.30.420.40 247 565 5.5E-5 T 28-03-2018 WM46_RS06600 d3eac7286f3d4bd0389cd85cefc7bead 993 SUPERFAMILY SSF53067 700 825 6.18E-5 T 28-03-2018 WM46_RS06600 d3eac7286f3d4bd0389cd85cefc7bead 993 SUPERFAMILY SSF53067 560 620 6.18E-5 T 28-03-2018 WM46_RS06600 d3eac7286f3d4bd0389cd85cefc7bead 993 PIRSF PIRSF034585 1 993 0.0 T 28-03-2018 IPR009216 Virulence factor SrfB WM46_RS06600 d3eac7286f3d4bd0389cd85cefc7bead 993 Gene3D G3DSA:3.30.420.40 566 785 1.2E-5 T 28-03-2018 WM46_RS06090 cf81f0c986006f49d8ec8163bcda618a 74 TIGRFAM TIGR02979 phageshock_pspD: phage shock protein PspD 13 71 2.3E-32 T 28-03-2018 IPR014321 Phage shock protein, PspD WM46_RS06090 cf81f0c986006f49d8ec8163bcda618a 74 Pfam PF09584 Phage shock protein PspD (Phageshock_PspD) 11 71 1.9E-31 T 28-03-2018 IPR014321 Phage shock protein, PspD WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 SMART SM00357 5 69 9.3E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 SUPERFAMILY SSF50249 3 68 3.26E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 PRINTS PR00050 Cold shock protein signature 42 60 1.1E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 PRINTS PR00050 Cold shock protein signature 27 36 1.1E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 PRINTS PR00050 Cold shock protein signature 6 21 1.1E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 PIRSF PIRSF002599 1 69 8.7E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 3.0E-33 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 Gene3D G3DSA:2.40.50.140 4 69 7.0E-30 T 28-03-2018 WM46_RS04920 2438b21594d2be1ec72263acfe9ba76f 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 28-03-2018 IPR019844 Cold-shock conserved site WM46_RS13305 2916205ade8d25b2cf917f6f6b3e7dd3 327 SUPERFAMILY SSF81345 4 323 9.15E-64 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS13305 2916205ade8d25b2cf917f6f6b3e7dd3 327 Pfam PF01032 FecCD transport family 16 323 4.1E-76 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS13305 2916205ade8d25b2cf917f6f6b3e7dd3 327 Gene3D G3DSA:1.10.3470.10 1 326 7.9E-56 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS05120 672b57596f4fc8f22ce369aae2c9bf4e 88 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 3.9E-25 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 WM46_RS05120 672b57596f4fc8f22ce369aae2c9bf4e 88 SUPERFAMILY SSF55229 32 85 1.22E-18 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 WM46_RS05120 672b57596f4fc8f22ce369aae2c9bf4e 88 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 1.3E-36 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 WM46_RS05120 672b57596f4fc8f22ce369aae2c9bf4e 88 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 19.902 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 WM46_RS05120 672b57596f4fc8f22ce369aae2c9bf4e 88 Gene3D G3DSA:3.30.1070.10 1 83 1.7E-29 T 28-03-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 4.6E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 TIGRFAM TIGR01083 nth: endonuclease III 4 194 2.8E-89 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 Gene3D G3DSA:1.10.340.30 25 116 2.0E-22 T 28-03-2018 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 2.2E-19 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 1.1E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 SMART SM00525 186 206 4.4E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 PIRSF PIRSF001435 1 210 3.5E-50 T 28-03-2018 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 SMART SM00478 38 185 4.0E-53 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 SUPERFAMILY SSF48150 3 208 1.29E-72 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 Gene3D G3DSA:1.10.1670.10 117 210 1.2E-29 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 WM46_RS07465 0b2100d1d4742a3fea322101e7e14952 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.305 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 SUPERFAMILY SSF111369 40 129 9.68E-9 T 28-03-2018 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 Pfam PF13437 HlyD family secretion protein 214 318 3.7E-13 T 28-03-2018 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 Gene3D G3DSA:1.10.287.470 124 175 1.5E-9 T 28-03-2018 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 Gene3D G3DSA:2.40.50.100 46 123 2.5E-10 T 28-03-2018 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 Pfam PF13533 Biotin-lipoyl like 48 94 3.7E-10 T 28-03-2018 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 SUPERFAMILY SSF111369 115 178 6.93E-5 T 28-03-2018 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 58 78 2.1E-5 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS20820 50be32f3258ad7b5fb4030a9f6bc9800 355 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 327 342 2.1E-5 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS17045 7e83a2f8447b1a959eb026f7a47d4917 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.138 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid WM46_RS17045 7e83a2f8447b1a959eb026f7a47d4917 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 WM46_RS17045 7e83a2f8447b1a959eb026f7a47d4917 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.3E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 WM46_RS17045 7e83a2f8447b1a959eb026f7a47d4917 130 SUPERFAMILY SSF54211 5 130 1.59E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS17045 7e83a2f8447b1a959eb026f7a47d4917 130 Gene3D G3DSA:3.30.230.10 3 130 1.2E-52 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 SUPERFAMILY SSF56784 1 262 1.4E-60 T 28-03-2018 IPR023214 HAD-like domain WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 Hamap MF_01847 HMP-PP phosphatase [cof]. 1 272 63.302 T 28-03-2018 IPR023938 HMP-PP phosphatase GO:0016818 WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 258 4.7E-49 T 28-03-2018 IPR023214 HAD-like domain WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 258 2.5E-56 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 Gene3D G3DSA:3.40.50.1000 1 267 6.5E-29 T 28-03-2018 IPR023214 HAD-like domain WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 210 232 - T 28-03-2018 WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 WM46_RS12585 b9155ae705fbeefc57f51ee6110df656 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 229 4.6E-47 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS03080 9d4324ece451d55126a763cd89d037c8 476 PIRSF PIRSF000977 4 476 5.4E-198 T 28-03-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 WM46_RS03080 9d4324ece451d55126a763cd89d037c8 476 SMART SM00479 11 204 0.0018 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS03080 9d4324ece451d55126a763cd89d037c8 476 Pfam PF08411 Exonuclease C-terminal 213 473 6.9E-104 T 28-03-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 WM46_RS03080 9d4324ece451d55126a763cd89d037c8 476 SUPERFAMILY SSF53098 10 475 2.82E-136 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS03080 9d4324ece451d55126a763cd89d037c8 476 Gene3D G3DSA:3.30.420.10 2 202 1.5E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS03080 9d4324ece451d55126a763cd89d037c8 476 Pfam PF00929 Exonuclease 14 189 7.2E-31 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS11870 3424b8381217b8d05f9e543e95d14503 243 Pfam PF04519 Polymer-forming cytoskeletal 116 209 6.4E-18 T 28-03-2018 IPR007607 Protein of unknown function DUF583 WM46_RS18485 9cd50917e0da56c8118c55e822ebdf49 316 Gene3D G3DSA:3.40.1190.20 6 311 2.4E-65 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS18485 9cd50917e0da56c8118c55e822ebdf49 316 SUPERFAMILY SSF53613 5 306 1.08E-75 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS18485 9cd50917e0da56c8118c55e822ebdf49 316 Pfam PF00294 pfkB family carbohydrate kinase 5 298 2.8E-56 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS18485 9cd50917e0da56c8118c55e822ebdf49 316 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 4.0E-14 T 28-03-2018 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.068 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 SUPERFAMILY SSF74731 3 117 2.62E-50 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 Pfam PF00453 Ribosomal protein L20 3 109 5.2E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 Gene3D G3DSA:1.10.1900.20 55 116 2.4E-29 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.4E-42 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.4E-42 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.4E-42 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS08025 fde9fa85e2bb35caa2b2d6f368888a0a 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.3E-53 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS23530 1e6f7e3400d4eeb1cf57aa6875143c16 570 Pfam PF00920 Dehydratase family 32 557 3.7E-163 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 WM46_RS23530 1e6f7e3400d4eeb1cf57aa6875143c16 570 SUPERFAMILY SSF52016 377 560 2.2E-42 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel WM46_RS23530 1e6f7e3400d4eeb1cf57aa6875143c16 570 SUPERFAMILY SSF143975 3 374 1.31E-102 T 28-03-2018 WM46_RS01365 206994ebb6168b45357b8191b16e6c10 80 ProDom PD857460 MEMBRANE YFDY INNER TRANSMEMBRANE STY2638 ECS3257 11 80 2.0E-23 T 28-03-2018 IPR024470 Protein of unknown function DUF2545 WM46_RS01365 206994ebb6168b45357b8191b16e6c10 80 Pfam PF10810 Protein of unknown function (DUF2545) 1 80 6.9E-35 T 28-03-2018 IPR024470 Protein of unknown function DUF2545 WM46_RS12385 162daacfb159f9b4177ba4dca318f0fe 109 Gene3D G3DSA:3.30.1310.10 1 109 8.0E-46 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM46_RS12385 162daacfb159f9b4177ba4dca318f0fe 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 98 23.402 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM46_RS12385 162daacfb159f9b4177ba4dca318f0fe 109 Pfam PF02575 YbaB/EbfC DNA-binding family 11 99 3.1E-35 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM46_RS12385 162daacfb159f9b4177ba4dca318f0fe 109 PIRSF PIRSF004555 3 109 5.1E-39 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM46_RS12385 162daacfb159f9b4177ba4dca318f0fe 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 105 1.6E-42 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM46_RS12385 162daacfb159f9b4177ba4dca318f0fe 109 SUPERFAMILY SSF82607 11 103 2.75E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 Gene3D G3DSA:1.10.10.10 5 100 4.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 76 2.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 Gene3D G3DSA:3.40.190.10 179 277 5.8E-18 T 28-03-2018 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 SUPERFAMILY SSF46785 17 123 2.01E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 SUPERFAMILY SSF53850 99 310 4.89E-32 T 28-03-2018 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 TIGRFAM TIGR02036 dsdC: D-serine deaminase transcriptional activator 8 308 9.7E-172 T 28-03-2018 IPR011781 D-serine deaminase transcriptional activator WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 Gene3D G3DSA:3.40.190.10 101 178 5.7E-12 T 28-03-2018 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 8.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 8.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 8.8E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19770 18ee21d166d8dd717be6bfb4672989b0 318 Pfam PF03466 LysR substrate binding domain 99 307 2.0E-28 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 ProSitePatterns PS00737 Thiolases signature 2. 333 349 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 Gene3D G3DSA:3.40.47.10 1 256 4.0E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 385 1.6E-144 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 PIRSF PIRSF000429 1 387 1.2E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 1 387 62.184 T 28-03-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 SUPERFAMILY SSF53901 1 259 2.49E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 ProSitePatterns PS00099 Thiolases active site. 368 381 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 Pfam PF00108 Thiolase, N-terminal domain 4 254 5.4E-86 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 Pfam PF02803 Thiolase, C-terminal domain 261 386 2.6E-49 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 SUPERFAMILY SSF53901 262 386 1.75E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 Gene3D G3DSA:3.40.47.10 257 384 2.1E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18965 11a3d6c3daf38b4e5c8a658a31f3435f 387 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 3 387 2.3E-241 T 28-03-2018 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726 WM46_RS16945 b29437b0c27887a2dbc6c22a6b517239 163 SUPERFAMILY SSF55804 9 155 3.14E-42 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS16945 b29437b0c27887a2dbc6c22a6b517239 163 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 13 155 8.1E-37 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS16945 b29437b0c27887a2dbc6c22a6b517239 163 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 9 155 3.9E-63 T 28-03-2018 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 WM46_RS16945 b29437b0c27887a2dbc6c22a6b517239 163 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 58 74 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS16945 b29437b0c27887a2dbc6c22a6b517239 163 Gene3D G3DSA:3.40.930.10 8 157 3.8E-38 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Gene3D G3DSA:1.20.150.20 384 510 8.7E-47 T 28-03-2018 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.0E-45 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 SUPERFAMILY SSF47917 383 511 2.88E-46 T 28-03-2018 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 1.8E-261 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 SUPERFAMILY SSF52540 96 381 2.53E-94 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Gene3D G3DSA:2.40.30.20 3 82 2.3E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 1.8E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 92 1.2E-12 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Gene3D G3DSA:3.40.50.300 83 375 4.6E-112 T 28-03-2018 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 SUPERFAMILY SSF50615 10 94 2.55E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS19515 88e36e16b1822c2b6654539496b5e8e6 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.065 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS00070 e422fa6b457f447595fc384d606d444b 462 Pfam PF04055 Radical SAM superfamily 88 199 1.8E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS00070 e422fa6b457f447595fc384d606d444b 462 TIGRFAM TIGR03978 rSAM_paired_1: His-Xaa-Ser system radical SAM maturase HxsB 3 460 1.5E-175 T 28-03-2018 IPR024023 His-Xaa-Ser system radical SAM maturase HxsB WM46_RS00070 e422fa6b457f447595fc384d606d444b 462 Pfam PF13353 4Fe-4S single cluster domain 92 163 4.1E-5 T 28-03-2018 WM46_RS00070 e422fa6b457f447595fc384d606d444b 462 SUPERFAMILY SSF102114 86 409 1.57E-28 T 28-03-2018 WM46_RS00070 e422fa6b457f447595fc384d606d444b 462 Gene3D G3DSA:3.20.20.70 82 440 1.2E-18 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS24390 e83ec154cd88ac3e4b3a659503a08d0b 245 Gene3D G3DSA:3.10.350.10 27 86 2.2E-18 T 28-03-2018 WM46_RS24390 e83ec154cd88ac3e4b3a659503a08d0b 245 Pfam PF01551 Peptidase family M23 139 232 4.1E-31 T 28-03-2018 IPR016047 Peptidase M23 WM46_RS24390 e83ec154cd88ac3e4b3a659503a08d0b 245 SMART SM00257 37 81 2.2E-16 T 28-03-2018 IPR018392 LysM domain WM46_RS24390 e83ec154cd88ac3e4b3a659503a08d0b 245 SUPERFAMILY SSF51261 37 236 1.73E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS24390 e83ec154cd88ac3e4b3a659503a08d0b 245 Pfam PF01476 LysM domain 38 80 1.5E-15 T 28-03-2018 IPR018392 LysM domain WM46_RS24390 e83ec154cd88ac3e4b3a659503a08d0b 245 Gene3D G3DSA:2.70.70.10 87 239 5.8E-38 T 28-03-2018 WM46_RS08720 4f42439fb6a342b6c4dc19d857708031 82 Pfam PF10848 Protein of unknown function (DUF2655) 1 82 2.6E-42 T 28-03-2018 IPR020371 Uncharacterised protein family YceQ WM46_RS08720 4f42439fb6a342b6c4dc19d857708031 82 ProDom PD078424 YCEQ 1 82 8.0E-34 T 28-03-2018 IPR020371 Uncharacterised protein family YceQ WM46_RS09395 845df68c7a60ce58275a7e791ea884d6 287 Pfam PF04909 Amidohydrolase 5 280 3.7E-34 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS09395 845df68c7a60ce58275a7e791ea884d6 287 SUPERFAMILY SSF51556 3 280 1.51E-52 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS09395 845df68c7a60ce58275a7e791ea884d6 287 Gene3D G3DSA:3.20.20.140 1 286 6.1E-37 T 28-03-2018 WM46_RS20450 66f465b4eb437274d921e7668e4430ee 330 Gene3D G3DSA:3.40.50.2300 131 329 4.0E-36 T 28-03-2018 WM46_RS20450 66f465b4eb437274d921e7668e4430ee 330 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 28 330 1.0E-166 T 28-03-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 WM46_RS20450 66f465b4eb437274d921e7668e4430ee 330 Pfam PF13407 Periplasmic binding protein domain 38 285 8.2E-62 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS20450 66f465b4eb437274d921e7668e4430ee 330 SUPERFAMILY SSF53822 24 318 1.27E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS20450 66f465b4eb437274d921e7668e4430ee 330 Gene3D G3DSA:3.40.50.2300 26 130 2.1E-20 T 28-03-2018 WM46_RS00540 10c281458f273a0ae884634c9bf95cb8 379 Gene3D G3DSA:1.20.1250.20 2 192 2.5E-14 T 28-03-2018 WM46_RS00540 10c281458f273a0ae884634c9bf95cb8 379 Pfam PF12832 MFS_1 like family 8 357 1.4E-44 T 28-03-2018 IPR024989 Major facilitator superfamily associated domain WM46_RS00540 10c281458f273a0ae884634c9bf95cb8 379 SUPERFAMILY SSF103473 7 371 6.02E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS00540 10c281458f273a0ae884634c9bf95cb8 379 Gene3D G3DSA:1.20.1250.20 193 375 7.0E-11 T 28-03-2018 WM46_RS00540 10c281458f273a0ae884634c9bf95cb8 379 PIRSF PIRSF004925 1 379 4.1E-117 T 28-03-2018 IPR026032 Probable 3-phenylpropionic acid transporter WM46_RS08910 65ebe4860c91e80a87e0787e6958db06 842 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 64 745 52.097 T 28-03-2018 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 WM46_RS08910 65ebe4860c91e80a87e0787e6958db06 842 SUPERFAMILY SSF53448 244 532 1.78E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS08910 65ebe4860c91e80a87e0787e6958db06 842 Pfam PF00535 Glycosyl transferase family 2 246 428 6.0E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS08910 65ebe4860c91e80a87e0787e6958db06 842 Gene3D G3DSA:3.90.550.10 223 503 3.6E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 SUPERFAMILY SSF64288 75 246 3.3E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 Pfam PF07702 UTRA domain 108 242 2.5E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 Gene3D G3DSA:3.40.1410.10 91 247 1.7E-35 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 8.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 8.6E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 SMART SM00345 28 87 2.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 87 5.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 SUPERFAMILY SSF46785 18 90 7.86E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 SMART SM00866 107 243 1.0E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS02685 3f69236e4afe5e80b2aa172e5335d896 248 Gene3D G3DSA:1.10.10.10 4 89 4.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS00770 298b4800ef4568a3ecf0a05c75ac7a93 213 Gene3D G3DSA:3.40.50.170 1 198 3.1E-68 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS00770 298b4800ef4568a3ecf0a05c75ac7a93 213 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS00770 298b4800ef4568a3ecf0a05c75ac7a93 213 SUPERFAMILY SSF53328 2 206 6.41E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS00770 298b4800ef4568a3ecf0a05c75ac7a93 213 Pfam PF00551 Formyl transferase 2 182 6.3E-66 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS00770 298b4800ef4568a3ecf0a05c75ac7a93 213 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 31.454 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 WM46_RS00770 298b4800ef4568a3ecf0a05c75ac7a93 213 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 192 1.3E-82 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 WM46_RS19085 c5a35f0d788ff0de7bdbe6aca753c5e9 297 TIGRFAM TIGR00688 rarD: protein RarD 9 261 2.7E-112 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 WM46_RS19085 c5a35f0d788ff0de7bdbe6aca753c5e9 297 SUPERFAMILY SSF103481 189 284 1.7E-7 T 28-03-2018 WM46_RS19085 c5a35f0d788ff0de7bdbe6aca753c5e9 297 Pfam PF00892 EamA-like transporter family 8 142 7.6E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS19085 c5a35f0d788ff0de7bdbe6aca753c5e9 297 SUPERFAMILY SSF103481 42 145 1.83E-13 T 28-03-2018 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 SUPERFAMILY SSF116726 291 374 4.45E-11 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Gene3D G3DSA:3.30.70.1450 216 291 1.3E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Hamap MF_01015 Putative transport protein YbjL [ybjL]. 1 557 57.729 T 28-03-2018 IPR023017 Transport protein YbjL, putative WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Pfam PF02080 TrkA-C domain 229 281 2.8E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Pfam PF02080 TrkA-C domain 305 371 2.5E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 SUPERFAMILY SSF116726 227 282 3.4E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Gene3D G3DSA:3.30.70.1450 295 375 7.4E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 391 541 3.5E-44 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 21 169 3.7E-38 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Pfam PF06826 Predicted Permease Membrane Region 385 554 5.8E-42 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS10200 b0b05c7516331dd636ed8a12fe09d90e 561 Pfam PF06826 Predicted Permease Membrane Region 17 182 1.1E-39 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 Pfam PF01820 D-ala D-ala ligase N-terminus 4 86 5.4E-17 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 PIRSF PIRSF039102 1 46 1.7E-7 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 PIRSF PIRSF039102 38 306 7.0E-98 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 Gene3D G3DSA:3.30.470.20 172 305 6.3E-38 T 28-03-2018 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 Gene3D G3DSA:3.30.1490.20 111 171 1.1E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 Pfam PF07478 D-ala D-ala ligase C-terminus 103 303 3.1E-69 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 63 74 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 306 36.224 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 SUPERFAMILY SSF52440 3 96 1.06E-28 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 305 1.5E-109 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 SUPERFAMILY SSF56059 97 302 1.85E-57 T 28-03-2018 WM46_RS14370 87463ff2523ff90f037b6e2663bfd895 306 Gene3D G3DSA:3.40.50.20 1 106 2.5E-30 T 28-03-2018 WM46_RS22155 7c1651d4af4e0b781538d76df419064d 121 Gene3D G3DSA:1.10.10.10 37 105 1.6E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22155 7c1651d4af4e0b781538d76df419064d 121 SUPERFAMILY SSF46785 44 104 2.01E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22155 7c1651d4af4e0b781538d76df419064d 121 Pfam PF04703 FaeA-like protein 56 95 4.4E-7 T 28-03-2018 IPR006793 FaeA-like protein GO:0006355|GO:0009289 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 SMART SM00420 11 63 1.7E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 Gene3D G3DSA:3.40.50.1360 68 244 1.4E-31 T 28-03-2018 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 29 43 3.4E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 43 61 3.4E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 SUPERFAMILY SSF46785 9 65 1.21E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 Pfam PF00455 DeoR C terminal sensor domain 79 235 2.2E-41 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 11 45 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 SUPERFAMILY SSF100950 80 235 3.43E-22 T 28-03-2018 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 SMART SM01134 76 237 7.6E-58 T 28-03-2018 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 Pfam PF08220 DeoR-like helix-turn-helix domain 11 63 2.8E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS06135 6bbe198196cc9c9f2f3c6462e6c99df6 256 Gene3D G3DSA:1.10.10.10 6 63 4.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23615 9bccf508ab72fdc68a9e6ee5cec8d7f4 158 Pfam PF14018 Domain of unknown function (DUF4234) 16 115 5.6E-6 T 28-03-2018 IPR025328 Domain of unknown function DUF4234 WM46_RS06130 8c5e7ab78aa9f29453914b9be379197e 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 453 1.0E-85 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS06130 8c5e7ab78aa9f29453914b9be379197e 537 Gene3D G3DSA:3.40.190.10 172 305 9.5E-31 T 28-03-2018 WM46_RS06130 8c5e7ab78aa9f29453914b9be379197e 537 Gene3D G3DSA:3.90.76.10 59 171 2.6E-34 T 28-03-2018 WM46_RS06130 8c5e7ab78aa9f29453914b9be379197e 537 SUPERFAMILY SSF53850 32 526 6.59E-137 T 28-03-2018 WM46_RS06130 8c5e7ab78aa9f29453914b9be379197e 537 Gene3D G3DSA:3.10.105.10 306 506 2.6E-58 T 28-03-2018 WM46_RS06130 8c5e7ab78aa9f29453914b9be379197e 537 PIRSF PIRSF002741 2 536 1.0E-108 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS04260 21134a4e7dcca48b7f797a92be31f88f 247 SUPERFAMILY SSF53335 20 242 5.93E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04260 21134a4e7dcca48b7f797a92be31f88f 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 4 242 4.0E-134 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 WM46_RS04260 21134a4e7dcca48b7f797a92be31f88f 247 Pfam PF13649 Methyltransferase domain 60 158 7.7E-15 T 28-03-2018 WM46_RS04260 21134a4e7dcca48b7f797a92be31f88f 247 Gene3D G3DSA:3.40.50.150 18 247 1.3E-41 T 28-03-2018 WM46_RS04260 21134a4e7dcca48b7f797a92be31f88f 247 PIRSF PIRSF006325 1 243 1.3E-133 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 WM46_RS04260 21134a4e7dcca48b7f797a92be31f88f 247 Hamap MF_01589 Carboxy-S-adenosyl-L-methionine synthase [cmoA]. 3 242 42.903 T 28-03-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 96 113 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 SUPERFAMILY SSF49354 15 141 1.52E-38 T 28-03-2018 IPR008962 PapD-like WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 Gene3D G3DSA:2.60.40.10 143 226 1.5E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 SUPERFAMILY SSF49584 136 223 3.01E-13 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 19 141 6.1E-40 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 Gene3D G3DSA:2.60.40.10 19 142 4.0E-33 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 164 219 4.5E-7 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 PRINTS PR00969 Pili chaperone signature 20 29 3.0E-26 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 PRINTS PR00969 Pili chaperone signature 158 173 3.0E-26 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 PRINTS PR00969 Pili chaperone signature 97 114 3.0E-26 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 PRINTS PR00969 Pili chaperone signature 123 138 3.0E-26 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS02645 b84c59315d1b38929342b0f1c97344c4 227 PRINTS PR00969 Pili chaperone signature 69 90 3.0E-26 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS09215 e4a70c7f475808ee4b8da5e956e88d17 250 Pfam PF04205 FMN-binding domain 138 229 4.1E-11 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 WM46_RS09215 e4a70c7f475808ee4b8da5e956e88d17 250 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 2 247 24.568 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 WM46_RS09215 e4a70c7f475808ee4b8da5e956e88d17 250 SMART SM00900 134 232 5.1E-18 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 WM46_RS09215 e4a70c7f475808ee4b8da5e956e88d17 250 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 6 239 1.7E-51 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 WM46_RS09215 e4a70c7f475808ee4b8da5e956e88d17 250 PIRSF PIRSF009437 2 247 4.6E-61 T 28-03-2018 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 WM46_RS21865 309d327fecdfb64d8d1bf50af93b5dee 355 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 350 2.7E-151 T 28-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 WM46_RS21865 309d327fecdfb64d8d1bf50af93b5dee 355 PIRSF PIRSF007313 1 355 4.0E-157 T 28-03-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 WM46_RS20655 1db87bdc292e88966508d85942768374 250 Pfam PF06564 Cellulose biosynthesis protein BcsQ 1 236 8.8E-106 T 28-03-2018 IPR017746 Cellulose synthase operon protein BcsQ WM46_RS20655 1db87bdc292e88966508d85942768374 250 TIGRFAM TIGR03371 cellulose_yhjQ: cellulose synthase operon protein YhjQ 1 239 2.1E-81 T 28-03-2018 IPR017746 Cellulose synthase operon protein BcsQ WM46_RS20655 1db87bdc292e88966508d85942768374 250 Gene3D G3DSA:3.40.50.300 3 238 1.4E-25 T 28-03-2018 WM46_RS20655 1db87bdc292e88966508d85942768374 250 SUPERFAMILY SSF52540 3 235 3.49E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07990 d8dff78b8b6dcbeae80b5e835f879a28 249 Pfam PF00005 ABC transporter 18 162 7.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07990 d8dff78b8b6dcbeae80b5e835f879a28 249 Gene3D G3DSA:3.40.50.300 12 238 2.6E-45 T 28-03-2018 WM46_RS07990 d8dff78b8b6dcbeae80b5e835f879a28 249 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS07990 d8dff78b8b6dcbeae80b5e835f879a28 249 SUPERFAMILY SSF52540 15 225 1.11E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07990 d8dff78b8b6dcbeae80b5e835f879a28 249 Hamap MF_01005 Vitamin B12 import ATP-binding protein BtuD [btuD]. 4 248 45.369 T 28-03-2018 IPR023693 ABC transporter, vitamin B12, BtuD GO:0005524|GO:0015889|GO:0016887 WM46_RS07990 d8dff78b8b6dcbeae80b5e835f879a28 249 SMART SM00382 25 210 1.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11450 bb0cda706b15fdaa0ee17fa6fdc15b26 192 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 39 180 1.0E-76 T 28-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 WM46_RS11450 bb0cda706b15fdaa0ee17fa6fdc15b26 192 Hamap MF_00837 Lipid A palmitoyltransferase PagP [pagP]. 9 192 42.856 T 28-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 WM46_RS11450 bb0cda706b15fdaa0ee17fa6fdc15b26 192 SUPERFAMILY SSF56925 33 192 1.1E-80 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS11450 bb0cda706b15fdaa0ee17fa6fdc15b26 192 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 43 189 8.1E-66 T 28-03-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 WM46_RS11450 bb0cda706b15fdaa0ee17fa6fdc15b26 192 Gene3D G3DSA:2.40.160.20 35 192 1.4E-65 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS05160 df4249a03b0d920ef8988290d2aa4d6f 514 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 511 6.7E-299 T 28-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 WM46_RS05160 df4249a03b0d920ef8988290d2aa4d6f 514 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 512 4.4E-301 T 28-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 WM46_RS05160 df4249a03b0d920ef8988290d2aa4d6f 514 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 514 368.471 T 28-03-2018 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 WM46_RS03075 8b85ed45ef3403a2ddb7c47239f8a35b 75 SUPERFAMILY SSF64307 3 74 4.71E-21 T 28-03-2018 IPR001455 TusA-like domain WM46_RS03075 8b85ed45ef3403a2ddb7c47239f8a35b 75 Gene3D G3DSA:3.30.110.40 2 75 4.0E-18 T 28-03-2018 IPR001455 TusA-like domain WM46_RS03075 8b85ed45ef3403a2ddb7c47239f8a35b 75 Pfam PF01206 Sulfurtransferase TusA 4 74 1.7E-18 T 28-03-2018 IPR001455 TusA-like domain WM46_RS03075 8b85ed45ef3403a2ddb7c47239f8a35b 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 28-03-2018 IPR001455 TusA-like domain WM46_RS17000 766f75575496450866412676265b5c98 291 ProSitePatterns PS01125 ROK family signature. 129 156 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS17000 766f75575496450866412676265b5c98 291 Pfam PF00480 ROK family 4 288 2.8E-85 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS17000 766f75575496450866412676265b5c98 291 Gene3D G3DSA:3.30.420.40 1 115 6.5E-22 T 28-03-2018 WM46_RS17000 766f75575496450866412676265b5c98 291 Hamap MF_01234 N-acetylmannosamine kinase [nanK]. 1 290 46.228 T 28-03-2018 IPR023945 N-acetylmannosamine kinase, bacterial GO:0005524|GO:0008270|GO:0009384|GO:0019262 KEGG: 00520+2.7.1.60|MetaCyc: PWY-6138 WM46_RS17000 766f75575496450866412676265b5c98 291 SUPERFAMILY SSF53067 1 287 1.52E-55 T 28-03-2018 WM46_RS17000 766f75575496450866412676265b5c98 291 Gene3D G3DSA:3.30.420.40 116 289 3.1E-46 T 28-03-2018 WM46_RS24705 711c7bd66780b7f1efecc265668809c2 851 Pfam PF13953 PapC C-terminal domain 770 835 6.1E-22 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS24705 711c7bd66780b7f1efecc265668809c2 851 Pfam PF13954 PapC N-terminal domain 28 171 2.8E-30 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS24705 711c7bd66780b7f1efecc265668809c2 851 Pfam PF00577 Outer membrane usher protein 190 761 7.1E-143 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS24705 711c7bd66780b7f1efecc265668809c2 851 SUPERFAMILY SSF141729 26 149 1.83E-20 T 28-03-2018 WM46_RS24705 711c7bd66780b7f1efecc265668809c2 851 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 304 314 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 Gene3D G3DSA:1.10.10.60 2 42 4.5E-15 T 28-03-2018 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 72 206 6.2E-25 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 8.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00400 Tetracycline repressor protein signature 131 150 8.8E-24 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00400 Tetracycline repressor protein signature 23 46 8.8E-24 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00400 Tetracycline repressor protein signature 75 94 8.8E-24 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00400 Tetracycline repressor protein signature 191 205 8.8E-24 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 PRINTS PR00400 Tetracycline repressor protein signature 95 118 8.8E-24 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 SUPERFAMILY SSF46689 6 66 6.62E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 SUPERFAMILY SSF48498 70 209 2.0E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 Gene3D G3DSA:1.10.10.60 43 81 1.8E-6 T 28-03-2018 WM46_RS15240 838cca5fbeb7d504be14c0ade4345f36 217 Gene3D G3DSA:1.10.357.10 82 215 5.2E-24 T 28-03-2018 WM46_RS10290 2fb8beb6194adcb0e23a3d3ccdeb74bd 321 Gene3D G3DSA:3.60.20.30 179 321 4.6E-52 T 28-03-2018 WM46_RS10290 2fb8beb6194adcb0e23a3d3ccdeb74bd 321 SUPERFAMILY SSF56235 4 309 1.23E-98 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS10290 2fb8beb6194adcb0e23a3d3ccdeb74bd 321 Pfam PF01112 Asparaginase 5 311 1.7E-117 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 WM46_RS25500 8b419a0a073bb4344a3546ccbdc7bd93 329 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 236 328 6.2E-43 T 28-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS25500 8b419a0a073bb4344a3546ccbdc7bd93 329 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 4 181 1.3E-72 T 28-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS25500 8b419a0a073bb4344a3546ccbdc7bd93 329 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 3 329 1.4E-191 T 28-03-2018 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 SMART SM00971 9 113 4.7E-65 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 Gene3D G3DSA:1.10.3130.10 2 135 3.7E-39 T 28-03-2018 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 Gene3D G3DSA:2.160.10.10 136 268 3.9E-30 T 28-03-2018 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 PIRSF PIRSF000441 75 266 3.2E-61 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 SUPERFAMILY SSF51161 4 260 1.94E-68 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 82 242 1.4E-75 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 193 226 6.2E-10 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 Pfam PF06426 Serine acetyltransferase, N-terminal 9 113 1.2E-39 T 28-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 WM46_RS20290 ad5560e9de2b2a88053c62e9ea17b253 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 202 230 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS05805 27af017f78a76accb73758b074308513 179 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 176 19.394 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 WM46_RS05805 27af017f78a76accb73758b074308513 179 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 178 2.7E-74 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 WM46_RS05805 27af017f78a76accb73758b074308513 179 Pfam PF04279 Intracellular septation protein A 1 175 1.5E-72 T 28-03-2018 IPR006008 Intracellular septation protein A GO:0016021 WM46_RS19245 5dfb9ebcfb1626e260e3d5fd360b7016 348 SUPERFAMILY SSF160355 54 318 1.96E-84 T 28-03-2018 WM46_RS19245 5dfb9ebcfb1626e260e3d5fd360b7016 348 Hamap MF_02025 ECA polysaccharide chain length modulation protein [wzzE]. 8 347 57.081 T 28-03-2018 IPR032895 ECA polysaccharide chain length modulation protein WzzE GO:0009246|GO:0016021 WM46_RS19245 5dfb9ebcfb1626e260e3d5fd360b7016 348 Pfam PF02706 Chain length determinant protein 15 71 2.5E-14 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 WM46_RS19245 5dfb9ebcfb1626e260e3d5fd360b7016 348 Gene3D G3DSA:1.10.287.210 203 294 1.1E-20 T 28-03-2018 WM46_RS19245 5dfb9ebcfb1626e260e3d5fd360b7016 348 Gene3D G3DSA:3.30.1890.10 42 202 9.3E-54 T 28-03-2018 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 Gene3D G3DSA:1.10.10.10 90 174 9.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 Pfam PF04542 Sigma-70 region 2 18 81 6.0E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 SUPERFAMILY SSF88946 16 98 8.63E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 Gene3D G3DSA:1.10.10.60 73 89 0.49 T 28-03-2018 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 SUPERFAMILY SSF88659 93 168 2.8E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 164 1.9E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 Gene3D G3DSA:1.10.1740.10 6 72 1.7E-10 T 28-03-2018 WM46_RS15390 6214fbed1307a8c6b3119d0c1aefd410 174 Pfam PF08281 Sigma-70, region 4 111 162 6.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 SUPERFAMILY SSF52540 3 301 3.2E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 PIRSF PIRSF006641 1 363 8.2E-158 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 1.5E-176 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 Gene3D G3DSA:3.40.50.300 1 80 2.6E-8 T 28-03-2018 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 46.593 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 SUPERFAMILY SSF81271 279 359 4.58E-36 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 2.0E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.9E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.3E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 Gene3D G3DSA:1.10.150.300 110 200 9.4E-28 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 WM46_RS05470 f4fa51a723abe173e3e125d09ea3665a 363 Gene3D G3DSA:3.10.20.30 263 362 5.3E-46 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 191 - T 28-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 89 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 SMART SM00100 2 122 1.1E-26 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 SUPERFAMILY SSF51206 8 136 1.03E-35 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 Gene3D G3DSA:1.10.10.10 145 210 9.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 Pfam PF00325 Bacterial regulatory proteins, crp family 166 197 1.8E-15 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 SUPERFAMILY SSF46785 139 207 3.64E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 6.5E-24 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 Gene3D G3DSA:2.60.120.10 4 144 6.0E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 166 182 8.8E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 197 8.8E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS17685 c9b73d94c2816acb50d358a803904515 210 SMART SM00419 160 208 4.5E-17 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 WM46_RS00890 347d7fd9cc0ae2e8439391407cf4391e 118 SUPERFAMILY SSF52833 1 115 1.57E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS00890 347d7fd9cc0ae2e8439391407cf4391e 118 Gene3D G3DSA:3.40.30.10 1 116 1.1E-36 T 28-03-2018 WM46_RS00890 347d7fd9cc0ae2e8439391407cf4391e 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 8.9E-34 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR WM46_RS00890 347d7fd9cc0ae2e8439391407cf4391e 118 Pfam PF03960 ArsC family 5 114 3.9E-17 T 28-03-2018 IPR006660 Arsenate reductase-like WM46_RS03455 f692f3aee96d26642b0b10013fd57aaa 370 Gene3D G3DSA:3.40.50.1970 1 163 1.1E-36 T 28-03-2018 WM46_RS03455 f692f3aee96d26642b0b10013fd57aaa 370 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 358 2.6E-106 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS03455 f692f3aee96d26642b0b10013fd57aaa 370 Gene3D G3DSA:1.20.1090.10 165 370 1.3E-54 T 28-03-2018 WM46_RS03455 f692f3aee96d26642b0b10013fd57aaa 370 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 154 182 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS03455 f692f3aee96d26642b0b10013fd57aaa 370 SUPERFAMILY SSF56796 3 368 3.27E-104 T 28-03-2018 WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 Hamap MF_01069 Glucans biosynthesis protein G [mdoG]. 6 509 63.264 T 28-03-2018 IPR023704 Glucan biosynthesis protein G WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 Gene3D G3DSA:2.60.40.10 398 511 3.3E-44 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 23 507 1.2E-199 T 28-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 SUPERFAMILY SSF74650 23 393 7.22E-165 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 Gene3D G3DSA:2.70.98.10 23 392 5.8E-168 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 PIRSF PIRSF006281 1 511 3.6E-240 T 28-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D WM46_RS08915 72823cd71d4971609b8290c7aa943400 511 SUPERFAMILY SSF81296 397 510 6.3E-34 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 5.2E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 5.2E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 5.2E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 5.2E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 5.2E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 5.2E-60 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 Gene3D G3DSA:2.40.50.140 1 124 1.5E-63 T 28-03-2018 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 PIRSF PIRSF002133 1 124 9.5E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 SUPERFAMILY SSF50249 3 123 1.63E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.634 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 2.6E-70 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17590 29495e0d2573e3eb61572cc610d4e48b 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 5.1E-43 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PIRSF PIRSF000207 1 599 9.6E-281 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 SUPERFAMILY SSF52218 60 210 2.86E-43 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Gene3D G3DSA:2.40.30.10 221 438 2.5E-46 T 28-03-2018 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 SUPERFAMILY SSF52343 444 599 1.01E-51 T 28-03-2018 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Gene3D G3DSA:3.40.50.360 51 220 5.3E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 494 505 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 548 556 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 525 541 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 386 393 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 456 475 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 270 280 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 481 490 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 419 428 2.8E-30 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Gene3D G3DSA:3.40.50.80 442 598 1.3E-36 T 28-03-2018 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Pfam PF00175 Oxidoreductase NAD-binding domain 457 563 6.9E-22 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Pfam PF00667 FAD binding domain 230 424 7.2E-24 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Pfam PF00258 Flavodoxin 67 195 8.1E-31 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 10 599 8.5E-283 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 Hamap MF_01541 Sulfite reductase [NADPH] flavoprotein alpha-component [cysJ]. 2 599 52.736 T 28-03-2018 IPR029758 Sulphite reductase [NADPH] flavoprotein, alpha chain, Proteobacteria GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 SUPERFAMILY SSF63380 228 446 2.2E-63 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00369 Flavodoxin signature 65 78 1.7E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00369 Flavodoxin signature 145 155 1.7E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00369 Flavodoxin signature 169 188 1.7E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS25210 df606b18ce1b6b2b11b26df3783d4009 599 PRINTS PR00369 Flavodoxin signature 113 124 1.7E-14 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 142 173 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 198 421 5.2E-61 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 194 206 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 113 133 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 168 179 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 142 159 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 PRINTS PR00732 Glycosyl hydrolase family 4 signature 75 91 1.0E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 SUPERFAMILY SSF56327 172 449 1.3E-70 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 Gene3D G3DSA:3.90.1820.10 2 313 4.3E-70 T 28-03-2018 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 Gene3D G3DSA:3.90.1820.10 314 451 8.9E-39 T 28-03-2018 WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 SUPERFAMILY SSF51735 5 171 1.1E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS21970 074021f9e07d69b51eaf59d2fc9e4ecb 451 Pfam PF02056 Family 4 glycosyl hydrolase 6 188 1.5E-79 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 WM46_RS20215 6643108c863488cfc7c9e85fb061fba3 358 Gene3D G3DSA:3.40.50.2000 202 358 6.5E-14 T 28-03-2018 WM46_RS20215 6643108c863488cfc7c9e85fb061fba3 358 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 104 322 1.3E-8 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 WM46_RS20215 6643108c863488cfc7c9e85fb061fba3 358 SUPERFAMILY SSF53756 43 355 6.8E-37 T 28-03-2018 WM46_RS20215 6643108c863488cfc7c9e85fb061fba3 358 Gene3D G3DSA:3.40.50.2000 32 191 7.6E-15 T 28-03-2018 WM46_RS07260 17be8159ea5c59a0fc9edb6bb96e37a5 231 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 172 1.8E-39 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM46_RS07260 17be8159ea5c59a0fc9edb6bb96e37a5 231 SUPERFAMILY SSF52540 1 212 1.56E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07260 17be8159ea5c59a0fc9edb6bb96e37a5 231 Pfam PF13500 AAA domain 4 207 2.9E-29 T 28-03-2018 WM46_RS07260 17be8159ea5c59a0fc9edb6bb96e37a5 231 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 214 23.972 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM46_RS07260 17be8159ea5c59a0fc9edb6bb96e37a5 231 PIRSF PIRSF006755 1 224 3.8E-62 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 WM46_RS07260 17be8159ea5c59a0fc9edb6bb96e37a5 231 Gene3D G3DSA:3.40.50.300 2 214 1.0E-45 T 28-03-2018 WM46_RS15265 a898034c36af5ba402e5ddb31aa8bacc 224 Gene3D G3DSA:3.40.50.150 100 210 1.2E-9 T 28-03-2018 WM46_RS15265 a898034c36af5ba402e5ddb31aa8bacc 224 Pfam PF02384 N-6 DNA Methylase 99 201 9.5E-6 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 WM46_RS15265 a898034c36af5ba402e5ddb31aa8bacc 224 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 102 118 7.7E-5 T 28-03-2018 WM46_RS15265 a898034c36af5ba402e5ddb31aa8bacc 224 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 134 148 7.7E-5 T 28-03-2018 WM46_RS15265 a898034c36af5ba402e5ddb31aa8bacc 224 SUPERFAMILY SSF53335 77 200 2.06E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS23435 49f1fc2c97b72ee0b041df7a4d3aee66 500 Gene3D G3DSA:3.40.50.300 14 447 2.5E-29 T 28-03-2018 WM46_RS23435 49f1fc2c97b72ee0b041df7a4d3aee66 500 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 500 1.1E-247 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal WM46_RS23435 49f1fc2c97b72ee0b041df7a4d3aee66 500 SUPERFAMILY SSF52540 13 369 6.79E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22710 ab57cea54888230321af34686bf3e950 478 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00145 Argininosuccinate lyase family signature 137 159 2.2E-5 T 28-03-2018 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 2.2E-5 T 28-03-2018 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 2.2E-5 T 28-03-2018 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 Gene3D G3DSA:1.10.40.30 419 468 3.2E-17 T 28-03-2018 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 Gene3D G3DSA:1.10.275.10 3 141 1.6E-52 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS22710 ab57cea54888230321af34686bf3e950 478 Pfam PF00206 Lyase 13 345 1.2E-112 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 4.8E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 4.8E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 4.8E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS22710 ab57cea54888230321af34686bf3e950 478 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 4.8E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS22710 ab57cea54888230321af34686bf3e950 478 Gene3D G3DSA:1.20.200.10 142 418 2.6E-73 T 28-03-2018 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 Pfam PF10415 Fumarase C C-terminus 411 464 1.3E-16 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 6 474 2.4E-273 T 28-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 WM46_RS22710 ab57cea54888230321af34686bf3e950 478 SUPERFAMILY SSF48557 1 458 8.39E-146 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS19230 b2980f156e54f7c538c2d07eac1de1ac 355 SUPERFAMILY SSF51735 1 346 5.08E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS19230 b2980f156e54f7c538c2d07eac1de1ac 355 Gene3D G3DSA:3.90.25.10 195 351 1.9E-50 T 28-03-2018 WM46_RS19230 b2980f156e54f7c538c2d07eac1de1ac 355 Gene3D G3DSA:3.40.50.720 1 194 1.2E-40 T 28-03-2018 WM46_RS19230 b2980f156e54f7c538c2d07eac1de1ac 355 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 341 2.2E-162 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 WM46_RS19230 b2980f156e54f7c538c2d07eac1de1ac 355 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 327 9.1E-99 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 Pfam PF00072 Response regulator receiver domain 13 121 9.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 SMART SM00862 156 232 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 SUPERFAMILY SSF52172 6 138 3.42E-39 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 SMART SM00448 11 121 5.2E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 SUPERFAMILY SSF46894 142 234 9.64E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 Gene3D G3DSA:1.10.10.10 152 239 2.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 231 1.3E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS02720 c9706a9bb688ce2b42afff3c40a8b768 240 Gene3D G3DSA:3.40.50.2300 8 151 3.8E-34 T 28-03-2018 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 SUPERFAMILY SSF51905 3 168 7.48E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 SUPERFAMILY SSF51905 251 301 7.48E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 Pfam PF01494 FAD binding domain 135 166 6.2E-5 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 280 1.7E-10 T 28-03-2018 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.7E-10 T 28-03-2018 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.7E-10 T 28-03-2018 WM46_RS19700 f157dfc8f2efc774f8141fa956c63adb 368 Gene3D G3DSA:3.50.50.60 3 328 6.4E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20120 65b6e2ce669d75f68821319a0d3733b1 213 Gene3D G3DSA:3.40.50.2020 1 193 4.5E-49 T 28-03-2018 WM46_RS20120 65b6e2ce669d75f68821319a0d3733b1 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 4.6E-72 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS20120 65b6e2ce669d75f68821319a0d3733b1 213 SUPERFAMILY SSF53271 2 208 4.98E-51 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS20120 65b6e2ce669d75f68821319a0d3733b1 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 37.088 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS20120 65b6e2ce669d75f68821319a0d3733b1 213 Pfam PF00156 Phosphoribosyl transferase domain 48 159 1.6E-11 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 Pfam PF13354 Beta-lactamase enzyme family 53 261 4.1E-39 T 28-03-2018 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 Gene3D G3DSA:3.40.710.10 26 287 6.0E-34 T 28-03-2018 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 SUPERFAMILY SSF56601 29 287 1.72E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 141 165 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 32 56 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 105 130 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 63 80 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 203 218 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 167 192 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS26065 60f2ef74d287f67c7ed3ab39d35619da 293 PRINTS PR00118 Beta-lactamase class A signature 220 235 4.3E-72 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 WM46_RS23820 3793955855dc172cfb278c981121c823 239 Gene3D G3DSA:1.20.120.530 93 235 3.2E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23820 3793955855dc172cfb278c981121c823 239 SUPERFAMILY SSF48008 96 218 4.71E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23820 3793955855dc172cfb278c981121c823 239 SUPERFAMILY SSF46785 6 78 1.11E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23820 3793955855dc172cfb278c981121c823 239 Gene3D G3DSA:1.10.10.10 3 76 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23820 3793955855dc172cfb278c981121c823 239 SMART SM00895 100 222 3.8E-13 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS23820 3793955855dc172cfb278c981121c823 239 SMART SM00345 15 74 1.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23820 3793955855dc172cfb278c981121c823 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23820 3793955855dc172cfb278c981121c823 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23820 3793955855dc172cfb278c981121c823 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 2.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23820 3793955855dc172cfb278c981121c823 239 Pfam PF07729 FCD domain 103 218 1.7E-21 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS14630 048354b0b3a83bb4b551a8333f63fe62 505 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 499 2.4E-117 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 WM46_RS14630 048354b0b3a83bb4b551a8333f63fe62 505 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 499 2.8E-167 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 WM46_RS14630 048354b0b3a83bb4b551a8333f63fe62 505 ProSitePatterns PS01303 BCCT family of transporters signature. 315 324 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS14630 048354b0b3a83bb4b551a8333f63fe62 505 Hamap MF_01049 L-carnitine/gamma-butyrobetaine antiporter [caiT]. 1 504 61.223 T 28-03-2018 IPR023449 L-carnitine/gamma-butyrobetaine antiporter CaiT GO:0016020|GO:0044667|GO:1900749|GO:1900751 WM46_RS13425 edfc1ef0e9c899038ca22e4522665cd9 317 PIRSF PIRSF018266 4 316 6.1E-88 T 28-03-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component WM46_RS13425 edfc1ef0e9c899038ca22e4522665cd9 317 Pfam PF16344 Domain of unknown function (DUF4974) 236 305 1.2E-7 T 28-03-2018 IPR032508 Protein FecR, C-terminal WM46_RS13425 edfc1ef0e9c899038ca22e4522665cd9 317 Pfam PF04773 FecR protein 110 202 4.3E-17 T 28-03-2018 IPR006860 FecR protein WM46_RS13425 edfc1ef0e9c899038ca22e4522665cd9 317 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 1.3E-9 T 28-03-2018 IPR032623 FecR, N-terminal WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 Pfam PF00593 TonB dependent receptor 275 730 9.3E-52 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 77 176 1.7E-13 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 79 731 2.8E-164 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 Gene3D G3DSA:2.40.170.20 189 731 1.6E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 714 731 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 Gene3D G3DSA:2.170.130.10 33 186 1.9E-17 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 49 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS08635 1c38904f9c7e0dc4a831024c8dd065a1 731 SUPERFAMILY SSF56935 38 731 9.16E-119 T 28-03-2018 WM46_RS14920 b5027c3036f463fb57b2fe65078959e2 407 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS14920 b5027c3036f463fb57b2fe65078959e2 407 Pfam PF07690 Major Facilitator Superfamily 27 368 2.5E-62 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14920 b5027c3036f463fb57b2fe65078959e2 407 Gene3D G3DSA:1.20.1250.20 18 214 3.4E-43 T 28-03-2018 WM46_RS14920 b5027c3036f463fb57b2fe65078959e2 407 Gene3D G3DSA:1.20.1250.20 215 407 3.5E-37 T 28-03-2018 WM46_RS14920 b5027c3036f463fb57b2fe65078959e2 407 SUPERFAMILY SSF103473 11 404 1.07E-89 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS23660 b0d6ba973b073bd657ac1ebac86bc954 96 Gene3D G3DSA:3.30.70.100 1 92 2.1E-18 T 28-03-2018 WM46_RS23660 b0d6ba973b073bd657ac1ebac86bc954 96 Hamap MF_02051 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [lsrG]. 1 96 36.46 T 28-03-2018 IPR033672 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase GO:0016853 WM46_RS23660 b0d6ba973b073bd657ac1ebac86bc954 96 SUPERFAMILY SSF54909 1 94 1.2E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS23660 b0d6ba973b073bd657ac1ebac86bc954 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.6E-15 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 Gene3D G3DSA:1.10.3860.10 1 411 2.2E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 4.1E-40 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 SUPERFAMILY SSF118215 7 403 1.7E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS04135 9f37f8a283a9862e3ab9fe33d8167ef3 422 Pfam PF00375 Sodium:dicarboxylate symporter family 7 402 1.2E-96 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 SMART SM00155 285 312 14.0 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 SMART SM00155 108 135 3.8E-8 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 SUPERFAMILY SSF56024 4 162 8.07E-41 T 28-03-2018 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 Gene3D G3DSA:3.30.870.10 2 167 1.4E-31 T 28-03-2018 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 Gene3D G3DSA:3.30.870.10 193 365 5.1E-28 T 28-03-2018 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 Hamap MF_01917 Cardiolipin synthase B [clsB]. 2 383 51.738 T 28-03-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 SUPERFAMILY SSF56024 187 358 1.61E-37 T 28-03-2018 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 Pfam PF13091 PLD-like domain 214 337 2.3E-25 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS10525 97ead6b6a3c5d2a2a01ec7f3aab49355 413 Pfam PF13091 PLD-like domain 26 162 3.2E-15 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS09195 879d9fe1dbd6661632c9c24737b7913d 427 Pfam PF12704 MacB-like periplasmic core domain 19 219 1.2E-8 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS09195 879d9fe1dbd6661632c9c24737b7913d 427 Pfam PF02687 FtsX-like permease family 332 419 5.3E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS18820 b638a6a762768221ee5e42c6363d5570 230 Pfam PF06178 Oligogalacturonate-specific porin protein (KdgM) 14 230 1.2E-87 T 28-03-2018 IPR009331 Oligogalacturonate-specific porin WM46_RS18820 b638a6a762768221ee5e42c6363d5570 230 SUPERFAMILY SSF56925 88 230 5.96E-5 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS18820 b638a6a762768221ee5e42c6363d5570 230 Gene3D G3DSA:2.40.160.40 23 230 1.0E-17 T 28-03-2018 WM46_RS26240 20e0efca732ac1a3eddca956307f675a 146 SUPERFAMILY SSF51306 15 138 2.96E-35 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS26240 20e0efca732ac1a3eddca956307f675a 146 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 54 64 4.0E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS26240 20e0efca732ac1a3eddca956307f675a 146 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 93 105 4.0E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS26240 20e0efca732ac1a3eddca956307f675a 146 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 65 76 4.0E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 WM46_RS26240 20e0efca732ac1a3eddca956307f675a 146 Gene3D G3DSA:2.10.109.10 22 140 9.1E-24 T 28-03-2018 WM46_RS26240 20e0efca732ac1a3eddca956307f675a 146 Pfam PF00717 Peptidase S24-like 57 117 3.3E-10 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS11220 6331409ccb338ff3bbcc225612a2f240 266 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 247 41.297 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 WM46_RS11220 6331409ccb338ff3bbcc225612a2f240 266 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 9 230 2.0E-22 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 WM46_RS11220 6331409ccb338ff3bbcc225612a2f240 266 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 125 143 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 WM46_RS11220 6331409ccb338ff3bbcc225612a2f240 266 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 259 7.6E-143 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 WM46_RS11220 6331409ccb338ff3bbcc225612a2f240 266 SUPERFAMILY SSF100950 1 263 6.7E-106 T 28-03-2018 WM46_RS11220 6331409ccb338ff3bbcc225612a2f240 266 Gene3D G3DSA:3.40.50.1360 1 266 2.5E-88 T 28-03-2018 WM46_RS13165 8c8cbc1831dcdf19bc5c29b62e46da0e 483 Gene3D G3DSA:1.10.4100.10 2 331 6.8E-102 T 28-03-2018 WM46_RS13165 8c8cbc1831dcdf19bc5c29b62e46da0e 483 Gene3D G3DSA:1.10.4100.10 391 483 1.3E-11 T 28-03-2018 WM46_RS13165 8c8cbc1831dcdf19bc5c29b62e46da0e 483 SUPERFAMILY SSF103378 13 482 1.44E-158 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 WM46_RS13165 8c8cbc1831dcdf19bc5c29b62e46da0e 483 Pfam PF03972 MmgE/PrpD family 18 462 3.0E-158 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 WM46_RS13165 8c8cbc1831dcdf19bc5c29b62e46da0e 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 5.0E-272 T 28-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 455 929 3.8E-99 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 SMART SM00869 650 918 3.1E-42 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 Gene3D G3DSA:2.40.128.130 608 929 3.7E-46 T 28-03-2018 WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 189 233 4.0E-7 T 28-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 SUPERFAMILY SSF51126 114 567 9.1E-22 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 SUPERFAMILY SSF103515 616 929 7.72E-48 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 Gene3D G3DSA:2.160.20.20 92 570 4.0E-26 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 370 401 5.0E-9 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS07015 aacb79729b632c5514537f84b83e9ebf 929 Pfam PF03797 Autotransporter beta-domain 653 907 3.3E-47 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS03575 18839546c48b455bed2bf52179071501 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 13 27 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS03575 18839546c48b455bed2bf52179071501 257 Gene3D G3DSA:3.30.950.10 129 249 1.1E-29 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03575 18839546c48b455bed2bf52179071501 257 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS03575 18839546c48b455bed2bf52179071501 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 215 1.8E-46 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03575 18839546c48b455bed2bf52179071501 257 Gene3D G3DSA:3.40.1010.10 8 128 6.4E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03575 18839546c48b455bed2bf52179071501 257 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 10 255 1.8E-100 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 WM46_RS03575 18839546c48b455bed2bf52179071501 257 SUPERFAMILY SSF53790 7 255 8.77E-70 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS10425 674f5e93172f58ac1da558fa5d02a5a2 746 Pfam PF00924 Mechanosensitive ion channel 515 713 3.1E-43 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM46_RS10425 674f5e93172f58ac1da558fa5d02a5a2 746 Gene3D G3DSA:2.30.30.60 575 622 5.1E-6 T 28-03-2018 WM46_RS10425 674f5e93172f58ac1da558fa5d02a5a2 746 SUPERFAMILY SSF82861 477 556 2.22E-12 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM46_RS10425 674f5e93172f58ac1da558fa5d02a5a2 746 Gene3D G3DSA:3.30.70.100 626 713 1.0E-5 T 28-03-2018 WM46_RS10425 674f5e93172f58ac1da558fa5d02a5a2 746 SUPERFAMILY SSF50182 558 616 1.28E-9 T 28-03-2018 IPR010920 LSM domain WM46_RS10425 674f5e93172f58ac1da558fa5d02a5a2 746 SUPERFAMILY SSF82689 627 721 7.59E-8 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 Gene3D G3DSA:1.10.10.10 104 186 6.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 SUPERFAMILY SSF46894 106 152 8.84E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 SMART SM00421 107 160 0.0042 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 Pfam PF00196 Bacterial regulatory proteins, luxR family 109 152 4.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 152 2.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 110 124 2.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS22375 4ac59bb3bebefbc6ecedfb3c2d561a2a 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 124 140 2.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03855 2340eb9fb26c1328d5fba82d96fe56af 137 Pfam PF13987 YedD-like protein 25 129 1.1E-54 T 28-03-2018 IPR025596 YedD-like protein WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.0E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 SUPERFAMILY SSF46955 2 126 1.4E-33 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 Gene3D G3DSA:1.10.1660.10 56 135 6.5E-15 T 28-03-2018 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 SMART SM00422 1 70 4.8E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 2.2E-61 T 28-03-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 Gene3D G3DSA:1.10.1660.10 1 55 2.5E-19 T 28-03-2018 WM46_RS12310 9030d255ec56ab98f957564dad3e1753 136 Pfam PF13411 MerR HTH family regulatory protein 2 67 6.3E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS09105 01f1e6883497c3a7f2f3ed1a7087e537 427 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 12 34 4.7E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM46_RS09105 01f1e6883497c3a7f2f3ed1a7087e537 427 Pfam PF04261 Dyp-type peroxidase family 65 413 4.4E-116 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 WM46_RS09105 01f1e6883497c3a7f2f3ed1a7087e537 427 SUPERFAMILY SSF54909 58 420 1.63E-96 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS09105 01f1e6883497c3a7f2f3ed1a7087e537 427 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 6 426 3.1E-180 T 28-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 WM46_RS09105 01f1e6883497c3a7f2f3ed1a7087e537 427 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 65 412 1.0E-103 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 Pfam PF00137 ATP synthase subunit C 11 69 1.5E-9 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 77 1.9E-31 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 Gene3D G3DSA:1.20.20.10 1 79 9.1E-16 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 SUPERFAMILY SSF81333 3 77 4.58E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 Hamap MF_01396 ATP synthase subunit c [atpH]. 10 75 14.323 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 12 31 1.6E-8 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 50 75 1.6E-8 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS19500 56b533cc370c1e28d908debdcf79489b 79 PRINTS PR00124 ATP synthase C subunit signature 33 48 1.6E-8 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 SUPERFAMILY SSF46689 138 181 2.33E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 Gene3D G3DSA:3.40.50.1390 2 105 4.7E-34 T 28-03-2018 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 SUPERFAMILY SSF53041 2 136 1.96E-44 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 Gene3D G3DSA:1.20.5.40 106 134 2.2E-15 T 28-03-2018 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 SMART SM00857 2 136 9.8E-56 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 Gene3D G3DSA:1.10.10.60 138 182 4.5E-8 T 28-03-2018 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 Pfam PF02796 Helix-turn-helix domain of resolvase 138 181 8.9E-12 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 WM46_RS03395 4ed5dedba7b8887cb871d1b8a1f17922 184 Pfam PF00239 Resolvase, N terminal domain 3 135 7.0E-44 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS10230 3a38e42f127b41ce2bf32082de1e7590 202 Pfam PF01569 PAP2 superfamily 62 169 2.8E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS10230 3a38e42f127b41ce2bf32082de1e7590 202 SUPERFAMILY SSF48317 2 200 2.49E-39 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS10230 3a38e42f127b41ce2bf32082de1e7590 202 Gene3D G3DSA:1.20.144.10 8 174 2.0E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS10230 3a38e42f127b41ce2bf32082de1e7590 202 SMART SM00014 61 169 3.4E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 SUPERFAMILY SSF82866 410 606 4.58E-40 T 28-03-2018 WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 SUPERFAMILY SSF82866 337 349 4.58E-40 T 28-03-2018 WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 615 50.614 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 Gene3D G3DSA:1.20.1640.10 383 607 1.3E-29 T 28-03-2018 WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 601 1.2E-150 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 Pfam PF07549 SecD/SecF GG Motif 120 140 7.4E-6 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 Pfam PF13721 SecD export protein N-terminal TM region 2 103 2.2E-38 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 Pfam PF02355 Protein export membrane protein 433 601 4.6E-15 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial WM46_RS12810 0c2deaafe587601e052c9c730cb8d2c0 615 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 345 594 4.3E-84 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 Gene3D G3DSA:3.40.50.620 1 212 1.1E-65 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 6 360 1.9E-158 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 Pfam PF03054 tRNA methyl transferase 6 360 3.6E-143 T 28-03-2018 WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 Gene3D G3DSA:2.30.30.280 213 280 9.3E-29 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 SUPERFAMILY SSF52402 4 295 3.75E-57 T 28-03-2018 WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 Gene3D G3DSA:2.40.30.10 282 365 2.2E-27 T 28-03-2018 WM46_RS08480 5caf3df2de3e209b4c81715abf846c84 368 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 6 361 40.8 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 WM46_RS22090 550ff9ce22e274a353ac0a344a7ab899 223 SUPERFAMILY SSF52833 58 219 1.78E-21 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS22090 550ff9ce22e274a353ac0a344a7ab899 223 Pfam PF01323 DSBA-like thioredoxin domain 114 214 2.3E-9 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 WM46_RS22090 550ff9ce22e274a353ac0a344a7ab899 223 Gene3D G3DSA:3.40.30.10 51 223 6.7E-20 T 28-03-2018 WM46_RS22090 550ff9ce22e274a353ac0a344a7ab899 223 PIRSF PIRSF001488 20 221 3.1E-23 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 55 325 1.2E-33 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 PIRSF PIRSF001394 30 548 2.1E-235 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 SUPERFAMILY SSF117457 361 536 3.14E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 Pfam PF05681 Fumarate hydratase (Fumerase) 51 326 1.8E-87 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 373 537 7.2E-64 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 Gene3D G3DSA:3.20.130.10 359 536 5.0E-68 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 Pfam PF05683 Fumarase C-terminus 332 537 1.2E-93 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS21985 28fca5adc1997f4ed71af8ed8644ea0c 548 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS07480 fdfdf5daa1221e2fc7b284f55c682627 286 Hamap MF_01639 Pyridoxal kinase PdxY [pdxY]. 1 286 53.814 T 28-03-2018 IPR023685 Pyridoxal kinase PdxY GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282 WM46_RS07480 fdfdf5daa1221e2fc7b284f55c682627 286 SUPERFAMILY SSF53613 1 279 7.95E-76 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS07480 fdfdf5daa1221e2fc7b284f55c682627 286 Pfam PF08543 Phosphomethylpyrimidine kinase 74 256 7.2E-16 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 WM46_RS07480 fdfdf5daa1221e2fc7b284f55c682627 286 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 1 285 4.7E-140 T 28-03-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 WM46_RS07480 fdfdf5daa1221e2fc7b284f55c682627 286 Gene3D G3DSA:3.40.1190.20 1 286 1.9E-62 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS00810 888f7ac8145319ad119e1b6fc807f1ff 439 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 423 1.4E-131 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS00810 888f7ac8145319ad119e1b6fc807f1ff 439 PIRSF PIRSF006351 1 432 3.8E-136 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS00810 888f7ac8145319ad119e1b6fc807f1ff 439 Pfam PF02378 Phosphotransferase system, EIIC 33 351 2.8E-59 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS00810 888f7ac8145319ad119e1b6fc807f1ff 439 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 423 1.4E-131 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 WM46_RS19020 5eb60a1cbb76a88720291761aec08160 475 Gene3D G3DSA:1.20.5.340 147 298 3.6E-24 T 28-03-2018 WM46_RS19020 5eb60a1cbb76a88720291761aec08160 475 Pfam PF02646 RmuC family 136 432 4.9E-107 T 28-03-2018 IPR003798 DNA recombination RmuC WM46_RS19020 5eb60a1cbb76a88720291761aec08160 475 Gene3D G3DSA:1.10.287.1060 324 419 0.11 T 28-03-2018 WM46_RS00955 be160d3501c2d79471ec5abbf4758bb9 159 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 143 1.4E-29 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 WM46_RS00955 be160d3501c2d79471ec5abbf4758bb9 159 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 143 1.2E-53 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 WM46_RS00955 be160d3501c2d79471ec5abbf4758bb9 159 SUPERFAMILY SSF52540 3 147 7.41E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00955 be160d3501c2d79471ec5abbf4758bb9 159 Gene3D G3DSA:3.40.50.300 2 157 1.6E-16 T 28-03-2018 WM46_RS00955 be160d3501c2d79471ec5abbf4758bb9 159 PIRSF PIRSF036409 1 148 6.0E-56 T 28-03-2018 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 WM46_RS17065 123e4ac34ace573fe60d86e970eff546 132 Pfam PF06295 Protein of unknown function (DUF1043) 6 126 1.0E-47 T 28-03-2018 IPR009386 Protein of unknown function DUF1043 WM46_RS17065 123e4ac34ace573fe60d86e970eff546 132 PIRSF PIRSF006318 1 132 2.9E-51 T 28-03-2018 IPR009386 Protein of unknown function DUF1043 WM46_RS03970 d76d550534e96d030555b253d5bba35e 1094 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 71 740 1.9E-137 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 WM46_RS03970 d76d550534e96d030555b253d5bba35e 1094 Gene3D G3DSA:3.40.50.300 179 504 1.9E-17 T 28-03-2018 WM46_RS03970 d76d550534e96d030555b253d5bba35e 1094 Pfam PF04851 Type III restriction enzyme, res subunit 315 485 1.1E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 WM46_RS03970 d76d550534e96d030555b253d5bba35e 1094 SUPERFAMILY SSF52540 281 539 4.26E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03970 d76d550534e96d030555b253d5bba35e 1094 SMART SM00487 312 522 6.1E-9 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS03970 d76d550534e96d030555b253d5bba35e 1094 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 9 225 3.9E-43 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 SUPERFAMILY SSF52172 4 190 1.21E-52 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Gene3D G3DSA:1.10.8.60 318 376 4.7E-26 T 28-03-2018 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 SMART SM00448 5 116 2.7E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Pfam PF02954 Bacterial regulatory protein, Fis family 418 454 2.4E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Pfam PF00072 Response regulator receiver domain 7 114 3.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 SMART SM00382 165 315 1.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Gene3D G3DSA:1.10.10.60 377 457 1.8E-19 T 28-03-2018 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Gene3D G3DSA:3.40.50.2300 2 133 5.3E-45 T 28-03-2018 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 169 182 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Pfam PF00158 Sigma-54 interaction domain 146 311 4.2E-73 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 Gene3D G3DSA:3.40.50.300 134 316 1.2E-27 T 28-03-2018 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 1.3E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 457 1.3E-12 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 SUPERFAMILY SSF46689 358 457 1.88E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS02060 8bf8ac4fc2c02421650a0c344c4d3332 461 SUPERFAMILY SSF52540 148 387 1.38E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01995 5f9b6bb3ba91c53a5737c91d0630b834 376 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS01995 5f9b6bb3ba91c53a5737c91d0630b834 376 SUPERFAMILY SSF47240 3 340 8.96E-116 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS01995 5f9b6bb3ba91c53a5737c91d0630b834 376 Pfam PF00268 Ribonucleotide reductase, small chain 32 332 5.8E-49 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS01995 5f9b6bb3ba91c53a5737c91d0630b834 376 Gene3D G3DSA:1.10.620.20 1 346 7.1E-115 T 28-03-2018 WM46_RS07405 8fc767cfd6e79058037f6814ba4d293a 390 SUPERFAMILY SSF53383 1 388 1.04E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS07405 8fc767cfd6e79058037f6814ba4d293a 390 Pfam PF00155 Aminotransferase class I and II 30 380 1.7E-54 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS07405 8fc767cfd6e79058037f6814ba4d293a 390 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 386 1.6E-117 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 WM46_RS07405 8fc767cfd6e79058037f6814ba4d293a 390 Gene3D G3DSA:3.90.1150.10 273 385 6.6E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS07405 8fc767cfd6e79058037f6814ba4d293a 390 Gene3D G3DSA:3.40.640.10 42 272 2.4E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS06490 5b32fedbaa04f54fe623d440f1e364a0 198 Pfam PF03848 Tellurite resistance protein TehB 1 193 2.8E-105 T 28-03-2018 IPR015985 Tellurite resistance methyltransferase TehB-like domain WM46_RS06490 5b32fedbaa04f54fe623d440f1e364a0 198 TIGRFAM TIGR00477 tehB: tellurite resistance protein TehB 1 196 9.3E-109 T 28-03-2018 IPR004537 Tellurite resistance methyltransferase, TehB GO:0005737|GO:0008757|GO:0046690 WM46_RS06490 5b32fedbaa04f54fe623d440f1e364a0 198 Gene3D G3DSA:3.40.50.150 1 197 3.2E-32 T 28-03-2018 WM46_RS06490 5b32fedbaa04f54fe623d440f1e364a0 198 SUPERFAMILY SSF53335 6 196 1.61E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS07790 49db4601f48f472ab8a577cf9b808785 270 SUPERFAMILY SSF53850 24 268 2.25E-73 T 28-03-2018 WM46_RS07790 49db4601f48f472ab8a577cf9b808785 270 Gene3D G3DSA:3.40.190.10 24 119 2.3E-24 T 28-03-2018 WM46_RS07790 49db4601f48f472ab8a577cf9b808785 270 Pfam PF03180 NLPA lipoprotein 25 268 3.9E-77 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS07790 49db4601f48f472ab8a577cf9b808785 270 PIRSF PIRSF002854 2 269 6.2E-91 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS07790 49db4601f48f472ab8a577cf9b808785 270 Gene3D G3DSA:3.40.190.10 120 269 6.1E-43 T 28-03-2018 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 SUPERFAMILY SSF53850 89 296 1.09E-33 T 28-03-2018 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.4E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 Pfam PF03466 LysR substrate binding domain 89 296 7.2E-39 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 SUPERFAMILY SSF46785 2 111 3.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 Gene3D G3DSA:3.40.190.10 175 266 3.6E-12 T 28-03-2018 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 Gene3D G3DSA:3.40.190.10 87 174 3.7E-19 T 28-03-2018 WM46_RS19315 4a60dc266bf3350677a8453a7630b089 302 Gene3D G3DSA:1.10.10.10 1 83 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 Gene3D G3DSA:3.30.980.10 553 713 2.0E-47 T 28-03-2018 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 SUPERFAMILY SSF55681 4 255 2.41E-108 T 28-03-2018 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 236 249 1.5E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 282 298 1.5E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 209 220 1.5E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 1.5E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 306 319 1.5E-33 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 7 854 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 Pfam PF01411 tRNA synthetases class II (A) 7 556 4.2E-241 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 SUPERFAMILY SSF50447 455 551 1.45E-20 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 696 7.5E-18 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 SUPERFAMILY SSF101353 256 465 6.15E-62 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 SUPERFAMILY SSF55186 552 708 9.81E-52 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 875 209.942 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 Gene3D G3DSA:3.30.930.10 2 252 2.2E-118 T 28-03-2018 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 Pfam PF02272 DHHA1 domain 732 871 3.9E-32 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 WM46_RS25530 a54e0311145c75660f7b989cec3f86d0 876 SMART SM00863 653 696 7.4E-22 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 WM46_RS06370 db98607f9ee1a2c6b26e6633c27690fe 190 Pfam PF00419 Fimbrial protein 4 190 9.0E-6 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS06370 db98607f9ee1a2c6b26e6633c27690fe 190 SUPERFAMILY SSF49401 6 41 1.04E-7 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06370 db98607f9ee1a2c6b26e6633c27690fe 190 SUPERFAMILY SSF49401 72 190 1.04E-7 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06370 db98607f9ee1a2c6b26e6633c27690fe 190 Gene3D G3DSA:2.60.40.1090 2 190 1.5E-16 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 SMART SM00358 156 224 1.6E-23 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 Pfam PF14622 Ribonuclease-III-like 20 141 1.2E-33 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 SMART SM00535 21 149 1.6E-59 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 Pfam PF00035 Double-stranded RNA binding motif 156 223 1.4E-14 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 Gene3D G3DSA:1.10.1520.10 5 148 2.6E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 Gene3D G3DSA:3.30.160.20 149 226 6.0E-21 T 28-03-2018 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 SUPERFAMILY SSF54768 109 223 2.36E-27 T 28-03-2018 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 ProSitePatterns PS00517 Ribonuclease III family signature. 38 46 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 9 223 1.7E-74 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 SUPERFAMILY SSF69065 5 159 5.06E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 WM46_RS00405 1d03d28a1b34de9890a23b7b601201b6 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 9 220 29.541 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 WM46_RS24570 5055a81687d16d97c1e2bd0522fc0c56 472 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 9 467 6.1E-75 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS24570 5055a81687d16d97c1e2bd0522fc0c56 472 Pfam PF13347 MFS/sugar transport protein 16 457 1.5E-73 T 28-03-2018 WM46_RS24570 5055a81687d16d97c1e2bd0522fc0c56 472 Gene3D G3DSA:1.20.1250.20 243 463 8.5E-12 T 28-03-2018 WM46_RS24570 5055a81687d16d97c1e2bd0522fc0c56 472 Gene3D G3DSA:1.20.1250.20 3 226 3.4E-15 T 28-03-2018 WM46_RS24570 5055a81687d16d97c1e2bd0522fc0c56 472 SUPERFAMILY SSF103473 13 438 1.22E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06645 b7ee1e37b256325f7ee3baa77e77eb7e 706 Gene3D G3DSA:2.170.130.10 23 163 2.2E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS06645 b7ee1e37b256325f7ee3baa77e77eb7e 706 Gene3D G3DSA:2.40.170.20 164 702 6.4E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS06645 b7ee1e37b256325f7ee3baa77e77eb7e 706 SUPERFAMILY SSF56935 23 703 1.91E-123 T 28-03-2018 WM46_RS06645 b7ee1e37b256325f7ee3baa77e77eb7e 706 Pfam PF00593 TonB dependent receptor 253 701 1.5E-56 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS06645 b7ee1e37b256325f7ee3baa77e77eb7e 706 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 48 701 2.0E-70 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS06645 b7ee1e37b256325f7ee3baa77e77eb7e 706 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 157 1.4E-22 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS12695 a9bc8600c609469fa96e66bd18a4b8da 169 SUPERFAMILY SSF89963 8 95 8.63E-30 T 28-03-2018 IPR007551 Protein of unknown function DUF520 WM46_RS12695 a9bc8600c609469fa96e66bd18a4b8da 169 Gene3D G3DSA:3.30.70.990 16 103 3.4E-29 T 28-03-2018 IPR035570 UPF0234 N-terminal domain WM46_RS12695 a9bc8600c609469fa96e66bd18a4b8da 169 SUPERFAMILY SSF89963 97 169 4.97E-29 T 28-03-2018 IPR007551 Protein of unknown function DUF520 WM46_RS12695 a9bc8600c609469fa96e66bd18a4b8da 169 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 7 169 30.224 T 28-03-2018 IPR007551 Protein of unknown function DUF520 WM46_RS12695 a9bc8600c609469fa96e66bd18a4b8da 169 Gene3D G3DSA:3.30.70.860 104 168 9.4E-34 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain WM46_RS12695 a9bc8600c609469fa96e66bd18a4b8da 169 Pfam PF04461 Protein of unknown function (DUF520) 8 168 5.4E-64 T 28-03-2018 IPR007551 Protein of unknown function DUF520 WM46_RS01765 32fc110dabd3e7320077fce0508410c4 220 SUPERFAMILY SSF56770 35 185 3.4E-65 T 28-03-2018 WM46_RS01765 32fc110dabd3e7320077fce0508410c4 220 Gene3D G3DSA:3.40.50.700 36 205 2.3E-38 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01765 32fc110dabd3e7320077fce0508410c4 220 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 37 178 1.8E-70 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01765 32fc110dabd3e7320077fce0508410c4 220 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 27 177 42.502 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01765 32fc110dabd3e7320077fce0508410c4 220 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 64 170 3.5E-22 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01765 32fc110dabd3e7320077fce0508410c4 220 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 144 160 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS17185 904d6341158b48792ac843d39c61add6 646 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 222 383 3.7E-11 T 28-03-2018 IPR000160 GGDEF domain WM46_RS17185 904d6341158b48792ac843d39c61add6 646 Pfam PF00563 EAL domain 404 628 2.3E-36 T 28-03-2018 IPR001633 EAL domain WM46_RS17185 904d6341158b48792ac843d39c61add6 646 Pfam PF00990 Diguanylate cyclase, GGDEF domain 224 380 3.5E-29 T 28-03-2018 IPR000160 GGDEF domain WM46_RS17185 904d6341158b48792ac843d39c61add6 646 SUPERFAMILY SSF141868 403 642 5.23E-35 T 28-03-2018 IPR001633 EAL domain WM46_RS17185 904d6341158b48792ac843d39c61add6 646 Gene3D G3DSA:3.20.20.450 389 645 4.3E-44 T 28-03-2018 IPR001633 EAL domain WM46_RS17185 904d6341158b48792ac843d39c61add6 646 Gene3D G3DSA:3.30.70.270 218 388 1.6E-25 T 28-03-2018 WM46_RS17185 904d6341158b48792ac843d39c61add6 646 Pfam PF17157 Gammaproteobacterial periplasmic sensor domain 34 130 1.2E-31 T 28-03-2018 IPR033423 Gammaproteobacterial periplasmic sensor domain GAPES4 WM46_RS17185 904d6341158b48792ac843d39c61add6 646 SMART SM00052 395 635 1.3E-55 T 28-03-2018 IPR001633 EAL domain WM46_RS17185 904d6341158b48792ac843d39c61add6 646 SUPERFAMILY SSF55073 230 387 3.37E-22 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS17185 904d6341158b48792ac843d39c61add6 646 SMART SM00267 213 385 3.9E-35 T 28-03-2018 IPR000160 GGDEF domain WM46_RS23205 e4d00ae642c65bbfa86535155050ed12 120 Gene3D G3DSA:3.40.1400.10 13 118 4.2E-4 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 WM46_RS23205 e4d00ae642c65bbfa86535155050ed12 120 Pfam PF14272 Glycine-rich SFCGS 4 117 3.9E-60 T 28-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 WM46_RS23205 e4d00ae642c65bbfa86535155050ed12 120 TIGRFAM TIGR03577 EF_0830: conserved hypothetical protein EF_0830/AHA_3911 4 118 2.5E-68 T 28-03-2018 IPR020034 Conserved hypothetical protein CHP03577, EF0830/AHA3911 WM46_RS10715 46715064e7a1d34f5e7abb44fac00a3d 346 Pfam PF01263 Aldose 1-epimerase 17 342 2.5E-88 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 WM46_RS10715 46715064e7a1d34f5e7abb44fac00a3d 346 SUPERFAMILY SSF74650 5 343 1.0E-108 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS10715 46715064e7a1d34f5e7abb44fac00a3d 346 PIRSF PIRSF005096 2 346 7.9E-124 T 28-03-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 WM46_RS10715 46715064e7a1d34f5e7abb44fac00a3d 346 TIGRFAM TIGR02636 galM_Leloir: galactose mutarotase 12 343 5.1E-145 T 28-03-2018 IPR013458 Aldose 1-epimerase, bacterial GO:0004034|GO:0006012 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 WM46_RS10715 46715064e7a1d34f5e7abb44fac00a3d 346 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 171 180 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 WM46_RS10715 46715064e7a1d34f5e7abb44fac00a3d 346 Gene3D G3DSA:2.70.98.10 7 345 2.0E-104 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS17490 acff94fd340d693184854d154eb30075 104 Gene3D G3DSA:2.30.30.30 2 93 2.2E-30 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 WM46_RS17490 acff94fd340d693184854d154eb30075 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 39 103 4.4E-23 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17490 acff94fd340d693184854d154eb30075 104 SUPERFAMILY SSF50104 4 100 4.69E-33 T 28-03-2018 IPR008991 Translation protein SH3-like domain WM46_RS17490 acff94fd340d693184854d154eb30075 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 8.1E-40 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17490 acff94fd340d693184854d154eb30075 104 Pfam PF00467 KOW motif 8 37 7.7E-5 T 28-03-2018 IPR005824 KOW WM46_RS17490 acff94fd340d693184854d154eb30075 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 97 20.168 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17490 acff94fd340d693184854d154eb30075 104 SMART SM00739 4 31 9.8E-4 T 28-03-2018 IPR005824 KOW WM46_RS17490 acff94fd340d693184854d154eb30075 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 PIRSF PIRSF000390 1 376 1.7E-121 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 Gene3D G3DSA:3.90.1150.10 243 376 3.7E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 SUPERFAMILY SSF53383 2 375 1.06E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 Gene3D G3DSA:3.40.640.10 1 242 4.5E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 TIGRFAM TIGR02379 ECA_wecE: TDP-4-keto-6-deoxy-D-glucose transaminase 1 375 1.0E-220 T 28-03-2018 IPR012749 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE-like MetaCyc: PWY-7315 WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 Hamap MF_02026 dTDP-4-amino-4,6-dideoxygalactose transaminase [wecE]. 1 376 79.049 T 28-03-2018 IPR032894 dTDP-4-amino-4,6-dideoxygalactose transaminase WecE GO:0009246|GO:0019180 MetaCyc: PWY-7315 WM46_RS19215 49528571ba8c09c0bb5f71e37f5b757b 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 371 2.9E-87 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS11775 a12bb9ab5963787653e86736f89e60e5 415 SUPERFAMILY SSF82689 322 397 1.44E-5 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM46_RS11775 a12bb9ab5963787653e86736f89e60e5 415 Pfam PF00924 Mechanosensitive ion channel 143 397 2.4E-66 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM46_RS11775 a12bb9ab5963787653e86736f89e60e5 415 Gene3D G3DSA:2.30.30.60 202 252 9.4E-10 T 28-03-2018 WM46_RS11775 a12bb9ab5963787653e86736f89e60e5 415 SUPERFAMILY SSF50182 187 253 4.58E-12 T 28-03-2018 IPR010920 LSM domain WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 SMART SM00387 332 440 5.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 289 2.2E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 Gene3D G3DSA:3.30.565.10 294 449 4.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 438 3.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 SMART SM00388 233 293 7.2E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 SUPERFAMILY SSF47384 217 291 5.89E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 SMART SM00304 180 232 6.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 SUPERFAMILY SSF55874 292 440 9.56E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 Pfam PF00672 HAMP domain 182 225 2.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS17850 bc65b67978b2007072c661a7772d24d1 450 Gene3D G3DSA:1.10.287.130 223 289 6.0E-13 T 28-03-2018 WM46_RS05525 a2bfc9c0badc5e5398474bcf1567a80f 559 Gene3D G3DSA:3.30.750.24 442 559 8.1E-16 T 28-03-2018 IPR002645 STAS domain WM46_RS05525 a2bfc9c0badc5e5398474bcf1567a80f 559 Pfam PF01740 STAS domain 451 554 2.2E-12 T 28-03-2018 IPR002645 STAS domain WM46_RS05525 a2bfc9c0badc5e5398474bcf1567a80f 559 SUPERFAMILY SSF52091 451 557 5.3E-15 T 28-03-2018 IPR002645 STAS domain WM46_RS05525 a2bfc9c0badc5e5398474bcf1567a80f 559 Pfam PF00916 Sulfate permease family 29 412 1.4E-76 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 WM46_RS05525 a2bfc9c0badc5e5398474bcf1567a80f 559 ProSitePatterns PS01130 SLC26A transporters signature. 58 79 - T 28-03-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 WM46_RS05525 a2bfc9c0badc5e5398474bcf1567a80f 559 TIGRFAM TIGR00815 sulP: sulfate permease 18 555 1.3E-147 T 28-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 WM46_RS05755 d7a01d5333be232dd7eca4a9fe96b4b5 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 300 2.3E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS05755 d7a01d5333be232dd7eca4a9fe96b4b5 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 70 1.1E-12 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM46_RS05755 d7a01d5333be232dd7eca4a9fe96b4b5 302 Gene3D G3DSA:1.10.3720.10 28 291 2.6E-37 T 28-03-2018 WM46_RS05755 d7a01d5333be232dd7eca4a9fe96b4b5 302 SUPERFAMILY SSF161098 100 283 9.68E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS02320 6707574bd0c4c78028e13b1f41f6d4e9 328 SUPERFAMILY SSF52540 6 170 1.83E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02320 6707574bd0c4c78028e13b1f41f6d4e9 328 Gene3D G3DSA:3.40.50.300 1 195 2.1E-29 T 28-03-2018 WM46_RS02320 6707574bd0c4c78028e13b1f41f6d4e9 328 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 242 321 1.1E-5 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal WM46_RS02320 6707574bd0c4c78028e13b1f41f6d4e9 328 SMART SM00833 240 323 0.0015 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal WM46_RS02320 6707574bd0c4c78028e13b1f41f6d4e9 328 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 178 4.7E-40 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Gene3D G3DSA:3.40.50.980 74 266 2.1E-54 T 28-03-2018 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Pfam PF00501 AMP-binding enzyme 83 522 7.8E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Gene3D G3DSA:3.30.300.30 518 650 4.3E-28 T 28-03-2018 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Gene3D G3DSA:3.40.50.980 267 429 9.8E-39 T 28-03-2018 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 2.7E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 53.082 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 SUPERFAMILY SSF56801 11 643 3.92E-191 T 28-03-2018 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Gene3D G3DSA:2.30.38.10 430 515 7.5E-12 T 28-03-2018 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 1.2E-18 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 WM46_RS21760 d50d9f884655c90ae006b4a8f295fc62 652 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 0.0 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 WM46_RS06305 383a5510f2b575c6d6aab2900d149f70 107 Pfam PF07027 Protein of unknown function (DUF1318) 19 107 3.7E-31 T 28-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 WM46_RS06305 383a5510f2b575c6d6aab2900d149f70 107 PIRSF PIRSF025560 1 107 1.8E-42 T 28-03-2018 IPR008309 Uncharacterised conserved protein UCP025560 WM46_RS14815 13fe4258b37e32edda386faa50ec5fdf 21 TIGRFAM TIGR02077 thr_lead_pep: thr operon leader peptide 1 21 2.2E-9 T 28-03-2018 IPR011720 Thr operon leader peptide GO:0009088|GO:0031554|GO:0031556 WM46_RS14815 13fe4258b37e32edda386faa50ec5fdf 21 Hamap MF_01907 thr operon leader peptide [thrL]. 1 21 11.934 T 28-03-2018 IPR011720 Thr operon leader peptide GO:0009088|GO:0031554|GO:0031556 WM46_RS14815 13fe4258b37e32edda386faa50ec5fdf 21 Pfam PF08254 Threonine leader peptide 1 21 5.0E-10 T 28-03-2018 IPR011720 Thr operon leader peptide GO:0009088|GO:0031554|GO:0031556 WM46_RS24375 36b454e3a5539714abb2047337672448 159 SUPERFAMILY SSF54292 8 81 9.57E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS24375 36b454e3a5539714abb2047337672448 159 SUPERFAMILY SSF47741 89 157 6.93E-23 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 WM46_RS24375 36b454e3a5539714abb2047337672448 159 Gene3D G3DSA:1.10.150.120 80 159 3.0E-25 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 WM46_RS24375 36b454e3a5539714abb2047337672448 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 59 1.8E-5 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS24375 36b454e3a5539714abb2047337672448 159 Pfam PF01799 [2Fe-2S] binding domain 78 152 1.1E-23 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 WM46_RS24375 36b454e3a5539714abb2047337672448 159 Gene3D G3DSA:3.10.20.30 4 79 1.0E-18 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS19600 08c457ff9cd21d8afbb7866fda809db7 392 SUPERFAMILY SSF103473 3 380 2.88E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19600 08c457ff9cd21d8afbb7866fda809db7 392 Hamap MF_01530 Multidrug resistance protein MdtL [mdtL]. 1 390 37.87 T 28-03-2018 IPR023697 Multidrug resistance protein MdtL GO:0005215|GO:0005886 WM46_RS19600 08c457ff9cd21d8afbb7866fda809db7 392 Pfam PF07690 Major Facilitator Superfamily 10 341 9.4E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19600 08c457ff9cd21d8afbb7866fda809db7 392 Gene3D G3DSA:1.20.1250.20 2 190 2.5E-31 T 28-03-2018 WM46_RS19600 08c457ff9cd21d8afbb7866fda809db7 392 Gene3D G3DSA:1.20.1250.20 196 392 4.5E-12 T 28-03-2018 WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 PIRSF PIRSF000412 1 417 1.9E-174 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 Pfam PF00464 Serine hydroxymethyltransferase 8 386 1.3E-188 T 28-03-2018 WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 SUPERFAMILY SSF53383 6 416 1.38E-184 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 Gene3D G3DSA:3.90.1150.10 276 416 8.9E-59 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 Gene3D G3DSA:3.40.640.10 37 275 1.1E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS00510 602b15af8b29601367d0c52aec86f762 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 53.482 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 WM46_RS03775 3e28e56495b18b6d38c973f12de49dfa 264 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 14 254 1.0E-79 T 28-03-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 WM46_RS03775 3e28e56495b18b6d38c973f12de49dfa 264 Pfam PF01311 Bacterial export proteins, family 1 14 246 1.3E-68 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 WM46_RS03775 3e28e56495b18b6d38c973f12de49dfa 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.8E-33 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 WM46_RS03775 3e28e56495b18b6d38c973f12de49dfa 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 1.8E-33 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 WM46_RS03775 3e28e56495b18b6d38c973f12de49dfa 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 80 99 1.8E-33 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 WM46_RS03775 3e28e56495b18b6d38c973f12de49dfa 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 1.8E-33 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 Pfam PF00381 PTS HPr component phosphorylation site 4 84 3.4E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 4 84 6.1E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 41 56 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 PRINTS PR00107 Phosphocarrier protein signature 14 30 2.2E-8 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 PRINTS PR00107 Phosphocarrier protein signature 55 72 2.2E-8 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 PRINTS PR00107 Phosphocarrier protein signature 40 55 2.2E-8 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 Gene3D G3DSA:3.30.1340.10 1 89 2.0E-22 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 SUPERFAMILY SSF55594 4 90 1.44E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS16955 c50ad0eb77852bc254cf39b883fa0b6a 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site WM46_RS07170 0d5af72b459db301519d357df2241445 488 Gene3D G3DSA:1.10.1040.10 279 486 7.6E-71 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS07170 0d5af72b459db301519d357df2241445 488 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 23 185 1.3E-52 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 WM46_RS07170 0d5af72b459db301519d357df2241445 488 SUPERFAMILY SSF51735 4 278 5.12E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07170 0d5af72b459db301519d357df2241445 488 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 215 227 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS07170 0d5af72b459db301519d357df2241445 488 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 213 459 2.8E-99 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 WM46_RS07170 0d5af72b459db301519d357df2241445 488 SUPERFAMILY SSF48179 280 483 1.36E-66 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS07170 0d5af72b459db301519d357df2241445 488 Gene3D G3DSA:3.40.50.720 1 278 4.2E-108 T 28-03-2018 WM46_RS07170 0d5af72b459db301519d357df2241445 488 PRINTS PR00084 Mannitol dehydrogenase signature 24 34 1.7E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS07170 0d5af72b459db301519d357df2241445 488 PRINTS PR00084 Mannitol dehydrogenase signature 245 260 1.7E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS07170 0d5af72b459db301519d357df2241445 488 PRINTS PR00084 Mannitol dehydrogenase signature 176 189 1.7E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS07170 0d5af72b459db301519d357df2241445 488 PRINTS PR00084 Mannitol dehydrogenase signature 215 228 1.7E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS08355 18dd6abb40708a903252e556a828ef89 248 Gene3D G3DSA:2.40.160.20 8 248 1.9E-12 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS08355 18dd6abb40708a903252e556a828ef89 248 Pfam PF06629 MltA-interacting protein MipA 28 248 1.1E-51 T 28-03-2018 IPR010583 MltA-interacting MipA WM46_RS20040 49120ede453a77343ee3bcdcce1f3393 252 Gene3D G3DSA:3.40.50.10490 94 222 8.3E-11 T 28-03-2018 WM46_RS20040 49120ede453a77343ee3bcdcce1f3393 252 SUPERFAMILY SSF53697 101 230 8.68E-15 T 28-03-2018 WM46_RS20040 49120ede453a77343ee3bcdcce1f3393 252 Pfam PF01418 Helix-turn-helix domain, rpiR family 11 65 2.1E-10 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS20040 49120ede453a77343ee3bcdcce1f3393 252 Gene3D G3DSA:1.10.10.10 7 93 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20040 49120ede453a77343ee3bcdcce1f3393 252 Pfam PF01380 SIS domain 103 203 1.9E-7 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS20040 49120ede453a77343ee3bcdcce1f3393 252 SUPERFAMILY SSF46689 11 71 9.32E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS02120 9d1bb06d6a9f03a6c8140f9cda80d552 551 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 28 519 54.324 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 WM46_RS02120 9d1bb06d6a9f03a6c8140f9cda80d552 551 Gene3D G3DSA:3.50.50.60 24 474 5.8E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02120 9d1bb06d6a9f03a6c8140f9cda80d552 551 SUPERFAMILY SSF51905 28 91 8.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02120 9d1bb06d6a9f03a6c8140f9cda80d552 551 SUPERFAMILY SSF51905 144 359 8.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02120 9d1bb06d6a9f03a6c8140f9cda80d552 551 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 32 517 5.2E-210 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 WM46_RS02120 9d1bb06d6a9f03a6c8140f9cda80d552 551 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 31 519 1.1E-236 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 4.0E-4 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 SUPERFAMILY SSF47336 2 77 1.44E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.7E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.327 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 Gene3D G3DSA:1.10.1200.10 1 78 8.2E-29 T 28-03-2018 WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site WM46_RS08675 10c00c0561de7dcf4030f0d748031d11 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 1.1E-38 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 WM46_RS12330 741bcbcb44faa7a6d3d82bb016c35920 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 156 1.2E-55 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC WM46_RS12330 741bcbcb44faa7a6d3d82bb016c35920 159 Pfam PF04073 Aminoacyl-tRNA editing domain 31 144 1.1E-21 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS12330 741bcbcb44faa7a6d3d82bb016c35920 159 SUPERFAMILY SSF55826 2 155 1.83E-43 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS12330 741bcbcb44faa7a6d3d82bb016c35920 159 Gene3D G3DSA:3.90.960.10 1 159 4.2E-42 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS12330 741bcbcb44faa7a6d3d82bb016c35920 159 PIRSF PIRSF006181 1 159 6.4E-57 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 Pfam PF01739 CheR methyltransferase, SAM binding domain 92 280 4.1E-59 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 Pfam PF03705 CheR methyltransferase, all-alpha domain 26 76 4.3E-18 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 SUPERFAMILY SSF53335 92 281 3.11E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PIRSF PIRSF000410 9 285 3.5E-101 T 28-03-2018 IPR026024 Chemotaxis protein methyltransferase CheR WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 Gene3D G3DSA:3.40.50.150 91 284 2.1E-46 T 28-03-2018 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 SMART SM00138 24 284 2.7E-125 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 SUPERFAMILY SSF47757 14 91 1.57E-24 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PRINTS PR00996 Glutamate methyltransferase family signature 85 97 2.4E-47 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PRINTS PR00996 Glutamate methyltransferase family signature 118 138 2.4E-47 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PRINTS PR00996 Glutamate methyltransferase family signature 243 266 2.4E-47 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PRINTS PR00996 Glutamate methyltransferase family signature 46 59 2.4E-47 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PRINTS PR00996 Glutamate methyltransferase family signature 152 168 2.4E-47 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 PRINTS PR00996 Glutamate methyltransferase family signature 224 238 2.4E-47 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 WM46_RS04175 73189716a29f9480fb30ee1c6b153e05 288 Gene3D G3DSA:1.10.155.10 16 90 2.0E-26 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal WM46_RS18735 e3e138ea0b896fda745761ddf02cf8d3 80 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 1 64 2.6E-24 T 28-03-2018 IPR022789 Antitoxin ParD WM46_RS18735 e3e138ea0b896fda745761ddf02cf8d3 80 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 4 71 2.1E-28 T 28-03-2018 IPR022789 Antitoxin ParD WM46_RS18735 e3e138ea0b896fda745761ddf02cf8d3 80 SUPERFAMILY SSF47598 4 44 1.03E-10 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM46_RS18735 e3e138ea0b896fda745761ddf02cf8d3 80 Gene3D G3DSA:1.10.1220.10 5 45 1.4E-12 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS10865 e85ca6ac900ab689c7ba4037382c12b0 149 TIGRFAM TIGR01501 MthylAspMutase: methylaspartate mutase, S subunit 3 135 3.3E-71 T 28-03-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS10865 e85ca6ac900ab689c7ba4037382c12b0 149 Pfam PF02310 B12 binding domain 6 96 4.0E-14 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM46_RS10865 e85ca6ac900ab689c7ba4037382c12b0 149 Hamap MF_00526 Glutamate mutase sigma subunit [glmS]. 1 137 37.193 T 28-03-2018 IPR006394 Glutamate mutase sigma subunit GO:0016866|GO:0019670 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS10865 e85ca6ac900ab689c7ba4037382c12b0 149 SUPERFAMILY SSF52242 4 138 2.35E-33 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 WM46_RS10865 e85ca6ac900ab689c7ba4037382c12b0 149 Gene3D G3DSA:3.40.50.280 1 148 1.3E-26 T 28-03-2018 WM46_RS20970 b640c171b749c5461fcbb978785ec89b 118 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 11 99 1.6E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS20970 b640c171b749c5461fcbb978785ec89b 118 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 10 91 1.2E-28 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 WM46_RS20970 b640c171b749c5461fcbb978785ec89b 118 Gene3D G3DSA:3.40.50.2300 8 106 5.3E-37 T 28-03-2018 WM46_RS20970 b640c171b749c5461fcbb978785ec89b 118 SUPERFAMILY SSF52794 9 103 2.44E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS21775 274a6b94296fa0e5598026aca07f98c7 187 Gene3D G3DSA:1.10.3820.10 107 182 1.4E-9 T 28-03-2018 WM46_RS21775 274a6b94296fa0e5598026aca07f98c7 187 Pfam PF13435 Cytochrome c554 and c-prime 36 82 0.0096 T 28-03-2018 IPR023155 Cytochrome c-552/4 WM46_RS21775 274a6b94296fa0e5598026aca07f98c7 187 Gene3D G3DSA:3.90.10.10 21 106 9.9E-10 T 28-03-2018 WM46_RS21775 274a6b94296fa0e5598026aca07f98c7 187 SUPERFAMILY SSF48695 6 168 5.66E-31 T 28-03-2018 IPR011031 Multihaem cytochrome WM46_RS21775 274a6b94296fa0e5598026aca07f98c7 187 TIGRFAM TIGR03146 cyt_nit_nrfB: cytochrome c nitrite reductase, pentaheme subunit 37 170 9.8E-58 T 28-03-2018 IPR017564 Cytochrome c nitrite reductase, pentahaem subunit GO:0006807|GO:0020037|GO:0042597 WM46_RS21775 274a6b94296fa0e5598026aca07f98c7 187 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 132 170 6.8E-5 T 28-03-2018 IPR010177 Doubled CXXCH motif WM46_RS13025 689f20f938d8671a4ddd0b35484f38b7 406 Pfam PF05992 SbmA/BacA-like family 80 393 2.3E-164 T 28-03-2018 IPR009248 SbmA/BacA-like GO:0005215|GO:0006810|GO:0016021 WM46_RS13025 689f20f938d8671a4ddd0b35484f38b7 406 SUPERFAMILY SSF90123 299 389 5.23E-6 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS13025 689f20f938d8671a4ddd0b35484f38b7 406 Gene3D G3DSA:1.20.1560.10 296 397 1.6E-4 T 28-03-2018 WM46_RS13025 689f20f938d8671a4ddd0b35484f38b7 406 Gene3D G3DSA:1.20.1560.10 70 284 1.6E-15 T 28-03-2018 WM46_RS21330 725081fc704e4cf6bccfd2d81e8b0e6b 149 Gene3D G3DSA:3.40.630.30 1 147 4.5E-26 T 28-03-2018 WM46_RS21330 725081fc704e4cf6bccfd2d81e8b0e6b 149 SUPERFAMILY SSF55729 3 142 1.89E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS21330 725081fc704e4cf6bccfd2d81e8b0e6b 149 Pfam PF13673 Acetyltransferase (GNAT) domain 37 130 1.6E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS15880 a451369e2c8449b62c2ad4b16b7b9a08 128 Pfam PF06755 CbtA_toxin of type IV toxin-antitoxin system 6 110 1.7E-55 T 28-03-2018 IPR009610 CbtA toxin of type IV toxin-antitoxin system WM46_RS13710 f7f608871089351f14f93e220d77bd16 246 SUPERFAMILY SSF141523 42 159 1.44E-9 T 28-03-2018 WM46_RS13710 f7f608871089351f14f93e220d77bd16 246 Gene3D G3DSA:2.40.440.10 40 174 3.3E-7 T 28-03-2018 WM46_RS13710 f7f608871089351f14f93e220d77bd16 246 Pfam PF03734 L,D-transpeptidase catalytic domain 78 159 1.1E-5 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 WM46_RS16535 82c942dc0ab7e12611f30feb8b8fa510 256 Gene3D G3DSA:3.20.20.60 4 255 4.6E-45 T 28-03-2018 WM46_RS16535 82c942dc0ab7e12611f30feb8b8fa510 256 SUPERFAMILY SSF51621 4 255 2.64E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS16535 82c942dc0ab7e12611f30feb8b8fa510 256 Hamap MF_01291 5-keto-4-deoxy-D-glucarate aldolase [garL]. 1 256 69.42 T 28-03-2018 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 WM46_RS16535 82c942dc0ab7e12611f30feb8b8fa510 256 TIGRFAM TIGR03239 GarL: 2-dehydro-3-deoxyglucarate aldolase 8 256 5.3E-146 T 28-03-2018 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 WM46_RS16535 82c942dc0ab7e12611f30feb8b8fa510 256 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 245 1.6E-62 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 WM46_RS18060 12ef586e134327e46316d57e1c350672 231 Pfam PF02678 Pirin 9 119 1.2E-37 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 WM46_RS18060 12ef586e134327e46316d57e1c350672 231 PIRSF PIRSF006232 1 230 3.5E-56 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 WM46_RS18060 12ef586e134327e46316d57e1c350672 231 Gene3D G3DSA:2.60.120.10 132 231 9.7E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS18060 12ef586e134327e46316d57e1c350672 231 SUPERFAMILY SSF51182 1 231 7.2E-80 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS18060 12ef586e134327e46316d57e1c350672 231 Gene3D G3DSA:2.60.120.10 11 131 3.7E-48 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 Gene3D G3DSA:3.40.50.300 21 184 1.8E-27 T 28-03-2018 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 SMART SM00382 54 181 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 SUPERFAMILY SSF52540 23 255 1.55E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 Gene3D G3DSA:1.10.8.60 187 257 1.0E-31 T 28-03-2018 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 1.1E-32 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 331 2.0E-40 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 238 8.5E-116 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 9.8E-147 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 336 184.977 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 Gene3D G3DSA:1.10.10.10 260 330 1.8E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04305 2e8ab69b624647d0683ada8f033187b0 336 SUPERFAMILY SSF46785 260 333 6.46E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02460 201da2f655261af8aa2165206afb7da4 332 Gene3D G3DSA:3.40.50.2300 122 332 1.2E-40 T 28-03-2018 WM46_RS02460 201da2f655261af8aa2165206afb7da4 332 SUPERFAMILY SSF53822 25 331 2.36E-82 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS02460 201da2f655261af8aa2165206afb7da4 332 Gene3D G3DSA:3.40.50.2300 20 116 3.8E-13 T 28-03-2018 WM46_RS02460 201da2f655261af8aa2165206afb7da4 332 Pfam PF13407 Periplasmic binding protein domain 28 299 6.4E-62 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Hamap MF_01016 Putative transport protein YidE [yidE]. 1 553 57.563 T 28-03-2018 IPR023018 Transport protein YidE, putative WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Pfam PF02080 TrkA-C domain 291 358 6.1E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Pfam PF02080 TrkA-C domain 212 272 1.1E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Gene3D G3DSA:3.30.70.1450 280 366 1.6E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 379 533 4.6E-49 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 16 166 1.3E-38 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Pfam PF06826 Predicted Permease Membrane Region 374 546 3.1E-47 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Pfam PF06826 Predicted Permease Membrane Region 11 179 9.9E-42 T 28-03-2018 IPR006512 YidE/YbjL duplication WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 SUPERFAMILY SSF116726 285 360 6.28E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 Gene3D G3DSA:3.30.70.1450 191 279 5.9E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS19725 c5eece1c860ef9bb02e7bc76b69e713a 553 SUPERFAMILY SSF116726 205 271 1.02E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 SUPERFAMILY SSF52313 6 235 3.14E-96 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 Pfam PF00318 Ribosomal protein S2 9 224 3.8E-94 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 Gene3D G3DSA:3.40.50.10490 5 241 1.8E-96 T 28-03-2018 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.313 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 8.5E-109 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 PRINTS PR00395 Ribosomal protein S2 signature 196 210 8.8E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 PRINTS PR00395 Ribosomal protein S2 signature 37 46 8.8E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 PRINTS PR00395 Ribosomal protein S2 signature 175 186 8.8E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 PRINTS PR00395 Ribosomal protein S2 signature 87 104 8.8E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 PRINTS PR00395 Ribosomal protein S2 signature 158 175 8.8E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 PRINTS PR00395 Ribosomal protein S2 signature 6 24 8.8E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 WM46_RS13980 559248e15d8247739f4bc27d45bcc343 241 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 180 3.3E-71 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 Gene3D G3DSA:3.30.70.940 6 119 8.2E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 Gene3D G3DSA:2.30.30.30 122 181 8.0E-22 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 SUPERFAMILY SSF82679 6 116 4.32E-40 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 181 24.779 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 SUPERFAMILY SSF50104 125 180 8.02E-20 T 28-03-2018 IPR008991 Translation protein SH3-like domain WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.9E-21 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 PRINTS PR00338 Transcription termination factor NUSG signature 139 154 1.9E-21 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 PRINTS PR00338 Transcription termination factor NUSG signature 157 173 1.9E-21 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 ProSitePatterns PS01014 Transcription termination factor nusG signature. 164 173 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 SMART SM00739 127 154 7.9E-7 T 28-03-2018 IPR005824 KOW WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 Pfam PF02357 Transcription termination factor nusG 7 112 1.9E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 SMART SM00738 6 115 8.6E-51 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 WM46_RS21160 30f22bfdfdaf577cf6f78f3e77d25c02 181 Pfam PF00467 KOW motif 130 162 5.5E-8 T 28-03-2018 IPR005824 KOW WM46_RS06455 efbf6e6c71c9b327e46b7c05e08cac2d 268 Gene3D G3DSA:3.20.20.380 3 268 1.2E-24 T 28-03-2018 WM46_RS06455 efbf6e6c71c9b327e46b7c05e08cac2d 268 SUPERFAMILY SSF51366 3 264 2.21E-22 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS06455 efbf6e6c71c9b327e46b7c05e08cac2d 268 Pfam PF03437 BtpA family 10 265 1.8E-105 T 28-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family WM46_RS06455 efbf6e6c71c9b327e46b7c05e08cac2d 268 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 11 267 1.1E-119 T 28-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family WM46_RS06455 efbf6e6c71c9b327e46b7c05e08cac2d 268 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 35 207 4.0E-94 T 28-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family WM46_RS06455 efbf6e6c71c9b327e46b7c05e08cac2d 268 PIRSF PIRSF005956 2 268 3.6E-81 T 28-03-2018 IPR005137 Membrane complex biogenesis protein, BtpA family WM46_RS23180 655e50cb394637f3d50bd59ad9d07b67 183 SUPERFAMILY SSF158710 37 179 2.62E-50 T 28-03-2018 IPR023153 PSPTO4464-like domain WM46_RS23180 655e50cb394637f3d50bd59ad9d07b67 183 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 16 180 23.627 T 28-03-2018 IPR006839 Ribosome-associated, YjgA WM46_RS23180 655e50cb394637f3d50bd59ad9d07b67 183 Pfam PF04751 Protein of unknown function (DUF615) 26 176 1.6E-54 T 28-03-2018 IPR006839 Ribosome-associated, YjgA WM46_RS23180 655e50cb394637f3d50bd59ad9d07b67 183 Gene3D G3DSA:1.10.60.30 38 106 4.8E-22 T 28-03-2018 WM46_RS23180 655e50cb394637f3d50bd59ad9d07b67 183 PIRSF PIRSF016183 10 183 6.1E-70 T 28-03-2018 IPR006839 Ribosome-associated, YjgA WM46_RS23180 655e50cb394637f3d50bd59ad9d07b67 183 Gene3D G3DSA:1.10.60.30 111 183 2.3E-29 T 28-03-2018 WM46_RS06205 b3d068be7d84484d35a751353cdd3af9 129 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 1.4E-25 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS06205 b3d068be7d84484d35a751353cdd3af9 129 SUPERFAMILY SSF69118 4 122 4.32E-38 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS06205 b3d068be7d84484d35a751353cdd3af9 129 Gene3D G3DSA:1.20.1290.10 7 129 3.6E-37 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS06205 b3d068be7d84484d35a751353cdd3af9 129 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 4 124 4.1E-55 T 28-03-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 WM46_RS17545 3d6a36dbd94d8c3c6441a69a14d8be76 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 204 1.9E-91 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17545 3d6a36dbd94d8c3c6441a69a14d8be76 209 SUPERFAMILY SSF50447 1 208 2.91E-80 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain WM46_RS17545 3d6a36dbd94d8c3c6441a69a14d8be76 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 207 40.32 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17545 3d6a36dbd94d8c3c6441a69a14d8be76 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site WM46_RS17545 3d6a36dbd94d8c3c6441a69a14d8be76 209 Gene3D G3DSA:4.10.960.10 57 165 1.0E-34 T 28-03-2018 WM46_RS17545 3d6a36dbd94d8c3c6441a69a14d8be76 209 Pfam PF00297 Ribosomal protein L3 27 182 6.8E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS12545 3bd9655ecf957fff270688b806c867b4 189 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 45 149 1.6E-41 T 28-03-2018 WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 Gene3D G3DSA:3.60.20.10 45 278 3.3E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 Pfam PF13522 Glutamine amidotransferase domain 63 202 6.7E-16 T 28-03-2018 WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 Gene3D G3DSA:3.40.50.2020 279 446 1.5E-38 T 28-03-2018 WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 2.5E-163 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 Pfam PF00156 Phosphoribosyl transferase domain 286 394 1.3E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 SUPERFAMILY SSF56235 2 259 1.89E-74 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 SUPERFAMILY SSF53271 252 485 1.01E-72 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 PIRSF PIRSF000485 1 483 2.2E-173 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 WM46_RS01600 8eea39a4bacd3c4834002cafca06d921 505 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.936 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 WM46_RS21605 1e6577e6696164858ed66f81130b6124 69 PIRSF PIRSF039008 1 66 2.3E-32 T 28-03-2018 IPR026042 Stress response protein YjbJ WM46_RS21605 1e6577e6696164858ed66f81130b6124 69 SUPERFAMILY SSF69047 1 69 3.4E-28 T 28-03-2018 IPR008462 CsbD-like domain WM46_RS21605 1e6577e6696164858ed66f81130b6124 69 Gene3D G3DSA:1.10.1470.10 1 69 5.4E-26 T 28-03-2018 IPR008462 CsbD-like domain WM46_RS21605 1e6577e6696164858ed66f81130b6124 69 Pfam PF05532 CsbD-like 4 56 6.3E-23 T 28-03-2018 IPR008462 CsbD-like domain WM46_RS23590 48620f72c3dc892ff822304966c25fce 68 Gene3D G3DSA:1.10.10.10 16 67 4.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23590 48620f72c3dc892ff822304966c25fce 68 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 13 59 1.0E-8 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA WM46_RS20260 17180db39767a8720c2fbf8a60acea45 427 Gene3D G3DSA:1.20.5.50 138 263 0.0024 T 28-03-2018 WM46_RS20260 17180db39767a8720c2fbf8a60acea45 427 Gene3D G3DSA:1.20.5.340 38 137 2.3E-5 T 28-03-2018 WM46_RS20260 17180db39767a8720c2fbf8a60acea45 427 Gene3D G3DSA:2.70.70.10 286 427 1.1E-32 T 28-03-2018 WM46_RS20260 17180db39767a8720c2fbf8a60acea45 427 Pfam PF01551 Peptidase family M23 328 421 5.5E-26 T 28-03-2018 IPR016047 Peptidase M23 WM46_RS20260 17180db39767a8720c2fbf8a60acea45 427 SUPERFAMILY SSF51261 227 425 4.92E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 523 647 3.6E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 SUPERFAMILY SSF55604 419 491 2.75E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 586 598 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 Pfam PF00367 phosphotransferase system, EIIB 421 454 6.4E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 Pfam PF02378 Phosphotransferase system, EIIC 12 324 3.8E-79 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 Gene3D G3DSA:3.30.1360.60 417 492 2.2E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 524 644 1.0E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 490 2.7E-204 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 SUPERFAMILY SSF51261 520 667 1.52E-50 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 432 449 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 383 479 4.1E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS11210 d0a5d9b1a36241ff0d0574a7ad95de82 671 Gene3D G3DSA:2.70.70.10 511 671 6.2E-54 T 28-03-2018 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 309 3.2E-39 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 PIRSF PIRSF000446 1 309 1.0E-143 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 Pfam PF00698 Acyl transferase domain 6 280 1.6E-38 T 28-03-2018 IPR014043 Acyl transferase WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 Gene3D G3DSA:3.40.366.10 1 184 5.7E-51 T 28-03-2018 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 SUPERFAMILY SSF52151 190 306 2.12E-81 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 SUPERFAMILY SSF52151 4 122 2.12E-81 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 Gene3D G3DSA:3.40.366.10 185 309 1.5E-31 T 28-03-2018 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 8.6E-134 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 WM46_RS08685 923da7fb0bd7a9d0be7a17cdc293ebbf 309 SUPERFAMILY SSF55048 128 197 4.84E-18 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 369 396 0.0032 T 28-03-2018 IPR011659 WD40-like Beta Propeller WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 199 223 4.3E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 281 315 4.4E-10 T 28-03-2018 IPR011659 WD40-like Beta Propeller WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Pfam PF07676 WD40-like Beta Propeller Repeat 237 272 1.8E-9 T 28-03-2018 IPR011659 WD40-like Beta Propeller WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Gene3D G3DSA:2.130.10.10 164 257 4.0E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 SUPERFAMILY SSF69304 155 428 2.88E-53 T 28-03-2018 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 SUPERFAMILY SSF52964 28 161 4.32E-40 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Gene3D G3DSA:2.130.10.150 258 429 6.9E-32 T 28-03-2018 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Hamap MF_00671 Protein TolB [tolB]. 5 426 34.51 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Gene3D G3DSA:3.40.50.10070 22 163 5.4E-38 T 28-03-2018 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 Pfam PF04052 TolB amino-terminal domain 23 121 6.9E-32 T 28-03-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 WM46_RS10805 8aaa3ab1156cae06d9abc098adda21f5 430 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 15 427 1.9E-156 T 28-03-2018 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 WM46_RS07495 11efc02dff1ef574818aaca801b0d330 107 SUPERFAMILY SSF141488 26 105 6.28E-23 T 28-03-2018 IPR018660 C-type lysozyme inhibitor WM46_RS07495 11efc02dff1ef574818aaca801b0d330 107 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 33 95 8.8E-16 T 28-03-2018 IPR018660 C-type lysozyme inhibitor WM46_RS19775 baa1a1f1a4e60d57165f2ebef281c5c5 349 Gene3D G3DSA:3.20.20.80 39 302 3.1E-19 T 28-03-2018 WM46_RS19775 baa1a1f1a4e60d57165f2ebef281c5c5 349 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 55 275 9.0E-13 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 WM46_RS19775 baa1a1f1a4e60d57165f2ebef281c5c5 349 SUPERFAMILY SSF51445 37 309 9.38E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS07245 bb7c80e28174f038333de7ba05ecd003 215 Gene3D G3DSA:1.10.3720.10 2 214 1.8E-33 T 28-03-2018 WM46_RS07245 bb7c80e28174f038333de7ba05ecd003 215 SUPERFAMILY SSF161098 12 204 1.57E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07245 bb7c80e28174f038333de7ba05ecd003 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 210 6.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS23775 3ccf4503bfffc62fdd1085dbb0609c68 255 Gene3D G3DSA:3.30.420.40 92 232 7.9E-33 T 28-03-2018 WM46_RS23775 3ccf4503bfffc62fdd1085dbb0609c68 255 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 3 247 1.2E-99 T 28-03-2018 IPR008275 CoA enzyme activase WM46_RS23775 3ccf4503bfffc62fdd1085dbb0609c68 255 SUPERFAMILY SSF53067 3 250 1.74E-31 T 28-03-2018 WM46_RS23775 3ccf4503bfffc62fdd1085dbb0609c68 255 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 248 4.0E-66 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 WM46_RS23775 3ccf4503bfffc62fdd1085dbb0609c68 255 Gene3D G3DSA:3.30.420.40 1 88 0.054 T 28-03-2018 WM46_RS02275 c681984f3b1b92ba96cb9f37f8629710 114 ProDom PD073777 YEJG CYTOPLASMIC SIMILAR Y2914 YPO1269 STY2456 ECS3073 ESCHERICHIA COLI 1 114 1.0E-59 T 28-03-2018 IPR020489 Uncharacterised protein family YejG WM46_RS02275 c681984f3b1b92ba96cb9f37f8629710 114 Pfam PF13989 YejG-like protein 4 108 2.8E-50 T 28-03-2018 IPR020489 Uncharacterised protein family YejG WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 SUPERFAMILY SSF53681 118 226 4.45E-25 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 222 1.8E-57 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 223 2.1E-49 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 80 88 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 Gene3D G3DSA:3.40.50.1860 118 214 1.4E-22 T 28-03-2018 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 Gene3D G3DSA:3.40.50.1860 1 117 5.6E-37 T 28-03-2018 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 189 199 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS24480 4c67e745cfee2e05ae8b368ec42348b4 244 SUPERFAMILY SSF53681 4 112 8.67E-32 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS05320 c88866c3fe7631472b6b5c387fda425c 254 Gene3D G3DSA:3.40.50.150 17 229 2.3E-33 T 28-03-2018 WM46_RS05320 c88866c3fe7631472b6b5c387fda425c 254 Pfam PF13649 Methyltransferase domain 43 140 5.3E-21 T 28-03-2018 WM46_RS05320 c88866c3fe7631472b6b5c387fda425c 254 SUPERFAMILY SSF53335 16 240 6.29E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04150 d286a13c5c9329ad9067519daa8222ee 251 Gene3D G3DSA:2.60.40.10 27 151 2.3E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS04150 d286a13c5c9329ad9067519daa8222ee 251 SUPERFAMILY SSF49354 23 150 3.14E-27 T 28-03-2018 IPR008962 PapD-like WM46_RS04150 d286a13c5c9329ad9067519daa8222ee 251 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 38 149 5.4E-21 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS04150 d286a13c5c9329ad9067519daa8222ee 251 Gene3D G3DSA:2.60.40.10 159 245 4.4E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS15275 eb61c6f7cdde61f531aff9c620629a15 328 PIRSF PIRSF037112 5 328 7.8E-115 T 28-03-2018 IPR017113 Antirestriction, ArdC WM46_RS15275 eb61c6f7cdde61f531aff9c620629a15 328 Pfam PF08401 Domain of unknown function (DUF1738) 18 146 8.0E-40 T 28-03-2018 IPR013610 Domain of unknown function DUF1738 WM46_RS16250 b663f11f926df484a4af0c5326a43676 201 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 176 9.5E-77 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS16250 b663f11f926df484a4af0c5326a43676 201 Gene3D G3DSA:3.20.130.10 1 176 1.3E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS16250 b663f11f926df484a4af0c5326a43676 201 Pfam PF05683 Fumarase C-terminus 9 175 6.2E-40 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS16250 b663f11f926df484a4af0c5326a43676 201 SUPERFAMILY SSF117457 3 174 7.85E-57 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS14600 a0cf66baa1bdee9383fd2efbd67a8994 77 Gene3D G3DSA:2.30.30.100 23 75 6.7E-26 T 28-03-2018 WM46_RS14600 a0cf66baa1bdee9383fd2efbd67a8994 77 Pfam PF06004 Bacterial protein of unknown function (DUF903) 26 74 2.1E-19 T 28-03-2018 IPR010305 Protein of unknown function DUF903 WM46_RS14600 a0cf66baa1bdee9383fd2efbd67a8994 77 SUPERFAMILY SSF50182 23 75 1.53E-15 T 28-03-2018 IPR010920 LSM domain WM46_RS10530 9af97275cae7104bcd7d144bf98c5a11 320 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 21 295 1.3E-15 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD WM46_RS23345 05d1455f40027751914257f9111590c4 308 TIGRFAM TIGR00746 arcC: carbamate kinase 6 301 1.7E-115 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 WM46_RS23345 05d1455f40027751914257f9111590c4 308 Pfam PF00696 Amino acid kinase family 6 276 1.4E-26 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS23345 05d1455f40027751914257f9111590c4 308 SUPERFAMILY SSF53633 6 301 2.49E-75 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS23345 05d1455f40027751914257f9111590c4 308 PIRSF PIRSF000723 3 303 2.4E-112 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 106 125 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 207 222 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 154 173 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 177 195 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 45 64 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 PRINTS PR01469 Bacterial carbamate kinase signature 258 273 1.1E-62 T 28-03-2018 WM46_RS23345 05d1455f40027751914257f9111590c4 308 Gene3D G3DSA:3.40.1160.10 3 303 3.4E-48 T 28-03-2018 WM46_RS17885 d04bb374a088a4b50394b7d61c55a8d8 78 Hamap MF_01586 Probable [Fe-S]-dependent transcriptional repressor [feoC]. 1 78 24.557 T 28-03-2018 IPR023732 Probable [Fe-S]-dependent transcriptional repressor WM46_RS17885 d04bb374a088a4b50394b7d61c55a8d8 78 SUPERFAMILY SSF46785 1 76 7.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17885 d04bb374a088a4b50394b7d61c55a8d8 78 Gene3D G3DSA:1.10.10.10 1 76 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17885 d04bb374a088a4b50394b7d61c55a8d8 78 Pfam PF09012 FeoC like transcriptional regulator 3 69 5.2E-16 T 28-03-2018 IPR015102 Transcriptional regulator HTH-type, FeoC WM46_RS06570 6f72acb8c89f0acbf4cd6b2b00d09f47 268 SUPERFAMILY SSF161098 6 257 1.57E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06570 6f72acb8c89f0acbf4cd6b2b00d09f47 268 Gene3D G3DSA:1.10.3720.10 7 264 7.1E-36 T 28-03-2018 WM46_RS06570 6f72acb8c89f0acbf4cd6b2b00d09f47 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 247 1.4E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 Pfam PF14849 YidC periplasmic domain 61 343 3.0E-88 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 353 533 3.4E-69 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 Pfam PF02096 60Kd inner membrane protein 354 533 1.0E-60 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR01900 YidC translocation/secretion protein signature 339 355 5.3E-30 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR01900 YidC translocation/secretion protein signature 488 512 5.3E-30 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR01900 YidC translocation/secretion protein signature 468 483 5.3E-30 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 324 344 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 66 87 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 158 178 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 415 438 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 499 522 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 251 266 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 217 235 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 PRINTS PR00701 60kDa inner membrane protein signature 462 484 1.8E-109 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 535 26.868 T 28-03-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 WM46_RS19630 840519b62282f63849d60f5ffacdeaec 548 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 352 5.5E-117 T 28-03-2018 IPR028053 Membrane insertase YidC, N-terminal WM46_RS22970 13abaf687d6e69fc7e1474b29e5199bc 249 Pfam PF00326 Prolyl oligopeptidase family 49 248 1.7E-14 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM46_RS22970 13abaf687d6e69fc7e1474b29e5199bc 249 Gene3D G3DSA:3.40.50.1820 2 249 2.7E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS22970 13abaf687d6e69fc7e1474b29e5199bc 249 SUPERFAMILY SSF53474 13 249 8.04E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 Pfam PF04055 Radical SAM superfamily 27 231 5.4E-23 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 Pfam PF13353 4Fe-4S single cluster domain 17 176 1.5E-9 T 28-03-2018 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 SUPERFAMILY SSF54862 28 94 7.85E-13 T 28-03-2018 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 Gene3D G3DSA:3.80.30.10 120 280 1.5E-25 T 28-03-2018 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 Gene3D G3DSA:3.30.70.20 57 79 9.7E-9 T 28-03-2018 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 TIGRFAM TIGR04041 activase_YjjW: glycine radical enzyme activase, YjjW family 6 282 8.9E-119 T 28-03-2018 IPR023912 Putative glycyl-radical enzyme activating enzyme YjjW WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 PIRSF PIRSF000371 1 287 1.0E-91 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 Gene3D G3DSA:3.30.70.20 80 119 0.0027 T 28-03-2018 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 SUPERFAMILY SSF102114 85 274 1.96E-14 T 28-03-2018 WM46_RS24085 66fa9e4805cc3b3b2bbc75b8845262e3 287 Gene3D G3DSA:3.30.70.20 30 56 0.047 T 28-03-2018 WM46_RS11050 4eb8a1b51c1b29608a53f0e67405e196 244 Gene3D G3DSA:3.20.20.370 2 244 1.7E-97 T 28-03-2018 WM46_RS11050 4eb8a1b51c1b29608a53f0e67405e196 244 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 240 43.249 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF WM46_RS11050 4eb8a1b51c1b29608a53f0e67405e196 244 SUPERFAMILY SSF88713 1 243 3.78E-91 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS11050 4eb8a1b51c1b29608a53f0e67405e196 244 Pfam PF03746 LamB/YcsF family 3 235 9.3E-93 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF WM46_RS07005 90c3dd643cb31a65e72a4336b3299a88 252 Gene3D G3DSA:1.10.150.290 177 230 7.4E-29 T 28-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS07005 90c3dd643cb31a65e72a4336b3299a88 252 Gene3D G3DSA:3.40.50.150 9 176 1.6E-26 T 28-03-2018 WM46_RS07005 90c3dd643cb31a65e72a4336b3299a88 252 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 2 251 45.15 T 28-03-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 WM46_RS07005 90c3dd643cb31a65e72a4336b3299a88 252 SUPERFAMILY SSF53335 16 240 4.71E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS07005 90c3dd643cb31a65e72a4336b3299a88 252 Pfam PF13489 Methyltransferase domain 12 176 2.9E-17 T 28-03-2018 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 Gene3D G3DSA:3.40.640.10 77 299 1.2E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 Gene3D G3DSA:3.90.1150.10 300 396 2.4E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 Gene3D G3DSA:3.90.1150.10 1 76 4.0E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 Pfam PF00155 Aminotransferase class I and II 27 392 2.9E-95 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 SUPERFAMILY SSF53383 1 396 6.41E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 7.3E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 7.3E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 7.3E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS09760 aee01f95ec0e2993669a33619d1202cf 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 7.3E-40 T 28-03-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 WM46_RS12220 c533448f940cd5f3184a630b00255b43 240 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 232 8.4E-112 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 WM46_RS12220 c533448f940cd5f3184a630b00255b43 240 Gene3D G3DSA:3.60.21.10 1 229 1.2E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS12220 c533448f940cd5f3184a630b00255b43 240 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 240 131.103 T 28-03-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 WM46_RS12220 c533448f940cd5f3184a630b00255b43 240 SUPERFAMILY SSF56300 2 222 2.85E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS12220 c533448f940cd5f3184a630b00255b43 240 Pfam PF00149 Calcineurin-like phosphoesterase 2 199 9.1E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS04995 a8d2f29d1cb2747e321fee6153980140 59 ProDom PD026807 UPF0181 YOAH YPTB1650 VV20310 VPA0916 VCA0569 YPO1774/Y2534/YP1619 PLU2693 VVA0806 PM0480 1 48 2.0E-18 T 28-03-2018 IPR005371 Uncharacterised protein family UPF0181 WM46_RS04995 a8d2f29d1cb2747e321fee6153980140 59 Pfam PF03701 Uncharacterised protein family (UPF0181) 1 49 4.8E-28 T 28-03-2018 IPR005371 Uncharacterised protein family UPF0181 WM46_RS04995 a8d2f29d1cb2747e321fee6153980140 59 Hamap MF_00507 UPF0181 protein YoaH [yoaH]. 1 58 20.171 T 28-03-2018 IPR005371 Uncharacterised protein family UPF0181 WM46_RS10960 2965e9916cd49895a5ec1b52743f0e6e 139 SUPERFAMILY SSF143744 1 134 4.45E-32 T 28-03-2018 WM46_RS10960 2965e9916cd49895a5ec1b52743f0e6e 139 Pfam PF03928 Haem-degrading 4 129 7.9E-28 T 28-03-2018 IPR005624 Haem-degrading WM46_RS00975 b279d1606a24454fb1b7109106244a2e 96 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 2 48 5.0E-18 T 28-03-2018 WM46_RS00975 b279d1606a24454fb1b7109106244a2e 96 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 20 39 - T 28-03-2018 IPR020808 Bacterial microcompartments protein, conserved site WM46_RS00975 b279d1606a24454fb1b7109106244a2e 96 SMART SM00877 2 78 2.2E-35 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS00975 b279d1606a24454fb1b7109106244a2e 96 Pfam PF00936 BMC domain 3 78 1.6E-27 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS00975 b279d1606a24454fb1b7109106244a2e 96 SUPERFAMILY SSF143414 1 89 2.09E-31 T 28-03-2018 WM46_RS15305 201974c29daf1a18b3c9cc6147f12cb0 299 Gene3D G3DSA:1.10.150.130 4 109 2.0E-7 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS15305 201974c29daf1a18b3c9cc6147f12cb0 299 Pfam PF12834 Phage integrase, N-terminal 7 95 4.4E-36 T 28-03-2018 IPR024457 Putative integrase, N-terminal WM46_RS15305 201974c29daf1a18b3c9cc6147f12cb0 299 Gene3D G3DSA:1.10.443.10 116 291 2.4E-11 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS15305 201974c29daf1a18b3c9cc6147f12cb0 299 Pfam PF12835 Integrase 108 255 2.5E-61 T 28-03-2018 IPR024456 Integrase catalytic domain, putative WM46_RS15305 201974c29daf1a18b3c9cc6147f12cb0 299 SUPERFAMILY SSF56349 12 281 1.47E-15 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 SUPERFAMILY SSF55874 261 424 3.67E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 422 1.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 SMART SM00304 158 210 5.1E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 Gene3D G3DSA:1.10.287.130 201 267 3.3E-9 T 28-03-2018 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 5.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 5.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 5.8E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 270 2.7E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 Gene3D G3DSA:3.30.565.10 277 427 4.7E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 SMART SM00388 211 271 7.9E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 SUPERFAMILY SSF47384 194 271 1.06E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS07365 e024afb443674b409b5bbe2c0a4f4e20 433 SMART SM00387 315 425 3.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 Gene3D G3DSA:1.10.260.40 7 62 5.5E-14 T 28-03-2018 WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 SUPERFAMILY SSF53822 63 316 1.69E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 SMART SM00354 5 75 2.0E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 Gene3D G3DSA:3.40.50.2300 173 331 6.0E-37 T 28-03-2018 WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 Gene3D G3DSA:3.40.50.2300 63 172 1.7E-27 T 28-03-2018 WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 SUPERFAMILY SSF47413 5 62 5.63E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 64 309 4.6E-31 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 WM46_RS18055 eb7cb008c4c98f68a23e6d8950c82f04 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 52 6.0E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Gene3D G3DSA:1.25.40.10 236 347 3.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 387 37.136 T 28-03-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Pfam PF13432 Tetratricopeptide repeat 113 170 0.0017 T 28-03-2018 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Gene3D G3DSA:1.25.40.10 162 235 2.8E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Gene3D G3DSA:1.25.40.10 120 161 3.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 SMART SM00028 180 213 72.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 SMART SM00028 141 174 290.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 SMART SM00028 214 247 0.0079 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 SMART SM00028 69 102 59.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 SMART SM00028 107 140 430.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Pfam PF14559 Tetratricopeptide repeat 191 246 4.5E-6 T 28-03-2018 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 SUPERFAMILY SSF48452 104 281 1.25E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS05935 6be25f12b5128c25b56a2e5653607725 389 Gene3D G3DSA:1.25.40.10 19 119 1.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS09625 fc565a96b4c403894b5a5a120e2da514 152 PIRSF PIRSF028777 1 139 3.8E-53 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 WM46_RS09625 fc565a96b4c403894b5a5a120e2da514 152 Pfam PF03733 Inner membrane component domain 77 127 8.7E-18 T 28-03-2018 IPR005185 Inner membrane component domain WM46_RS09625 fc565a96b4c403894b5a5a120e2da514 152 Pfam PF03733 Inner membrane component domain 4 53 5.5E-9 T 28-03-2018 IPR005185 Inner membrane component domain WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 TIGRFAM TIGR02163 napH_: ferredoxin-type protein, NapH/MauN family 24 278 2.5E-115 T 28-03-2018 IPR011886 Ferredoxin-type protein, NapH/MauN family GO:0005506 WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 Pfam PF12801 4Fe-4S binding domain 179 211 7.3E-4 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 Pfam PF12801 4Fe-4S binding domain 83 126 8.3E-12 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 Pfam PF13237 4Fe-4S dicluster domain 221 270 1.0E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 Gene3D G3DSA:3.30.70.20 235 280 5.6E-8 T 28-03-2018 WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 SUPERFAMILY SSF54862 191 280 9.12E-21 T 28-03-2018 WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 SUPERFAMILY SSF54862 104 143 9.12E-21 T 28-03-2018 WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 226 237 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS02150 6ce9832e20e661f87e21f9b934c68eb3 287 Gene3D G3DSA:3.30.70.20 195 234 6.7E-7 T 28-03-2018 WM46_RS14720 4a4b20ce2e2a3c20ae265a0e7be7afde 299 SUPERFAMILY SSF53850 90 287 1.13E-26 T 28-03-2018 WM46_RS14720 4a4b20ce2e2a3c20ae265a0e7be7afde 299 Pfam PF03466 LysR substrate binding domain 96 284 1.0E-11 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS14720 4a4b20ce2e2a3c20ae265a0e7be7afde 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.2E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14720 4a4b20ce2e2a3c20ae265a0e7be7afde 299 Gene3D G3DSA:1.10.10.10 1 86 7.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14720 4a4b20ce2e2a3c20ae265a0e7be7afde 299 Gene3D G3DSA:3.40.190.10 93 223 1.3E-4 T 28-03-2018 WM46_RS14720 4a4b20ce2e2a3c20ae265a0e7be7afde 299 SUPERFAMILY SSF46785 2 85 2.13E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 Pfam PF03466 LysR substrate binding domain 93 296 5.0E-33 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 SUPERFAMILY SSF53850 92 300 5.79E-39 T 28-03-2018 WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 SUPERFAMILY SSF46785 5 114 6.68E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 Gene3D G3DSA:3.40.190.10 179 263 1.8E-15 T 28-03-2018 WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.9E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 Gene3D G3DSA:1.10.10.10 1 87 2.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23795 ddd62b0f66f02c8dadeef1f02f10d869 308 Gene3D G3DSA:3.40.190.10 92 178 2.3E-10 T 28-03-2018 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 195 1.0E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 SUPERFAMILY SSF46894 130 197 1.16E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 ProSitePatterns PS00622 LuxR-type HTH domain signature. 156 183 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 1.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 1.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 1.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 Gene3D G3DSA:1.10.10.10 80 199 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20740 30feb010dd502c0147ae31d95100daac 199 SMART SM00421 139 196 3.1E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS20150 a829eae9f6e1d3a9a8d96fa127c656c4 55 SUPERFAMILY SSF57829 1 53 3.3E-20 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 WM46_RS20150 a829eae9f6e1d3a9a8d96fa127c656c4 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 5.9E-28 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS20150 a829eae9f6e1d3a9a8d96fa127c656c4 55 Pfam PF00471 Ribosomal protein L33 7 53 7.3E-19 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS20150 a829eae9f6e1d3a9a8d96fa127c656c4 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 15.857 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS20150 a829eae9f6e1d3a9a8d96fa127c656c4 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS16700 e6c2a22e490d07b565fac048e939674a 100 Gene3D G3DSA:3.40.1440.10 2 91 1.9E-5 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS16700 e6c2a22e490d07b565fac048e939674a 100 Pfam PF01541 GIY-YIG catalytic domain 4 75 2.8E-12 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS16700 e6c2a22e490d07b565fac048e939674a 100 Hamap MF_01029 UPF0213 protein YhbQ [yhbQ]. 1 92 31.18 T 28-03-2018 IPR022992 Uncharacterised protein family UPF0213, GIY-YIG endonuclease WM46_RS16700 e6c2a22e490d07b565fac048e939674a 100 SUPERFAMILY SSF82771 3 72 5.49E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS14745 ea92add983328beb0f5f1a6457423ff1 254 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 102 254 9.0E-13 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS14745 ea92add983328beb0f5f1a6457423ff1 254 SUPERFAMILY SSF111364 31 254 4.45E-27 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS14745 ea92add983328beb0f5f1a6457423ff1 254 Gene3D G3DSA:2.40.230.20 99 246 1.6E-7 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 SUPERFAMILY SSF53850 93 293 3.62E-39 T 28-03-2018 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 Gene3D G3DSA:3.40.190.10 92 179 6.2E-11 T 28-03-2018 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 SUPERFAMILY SSF46785 6 90 1.74E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 7.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 7.4E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 Gene3D G3DSA:1.10.10.10 1 91 9.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 Gene3D G3DSA:3.40.190.10 180 268 5.8E-23 T 28-03-2018 WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 Pfam PF03466 LysR substrate binding domain 91 292 1.2E-35 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS11935 8bd41af897db47cc9193fd3847890177 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.5E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 TIGRFAM TIGR00232 tktlase_bact: transketolase 5 662 0.0 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 Pfam PF02780 Transketolase, C-terminal domain 540 655 9.3E-19 T 28-03-2018 IPR033248 Transketolase, C-terminal domain WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 Gene3D G3DSA:3.40.50.970 364 540 2.0E-41 T 28-03-2018 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 SUPERFAMILY SSF52922 533 663 1.44E-43 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 3.3E-172 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 Gene3D G3DSA:3.40.50.920 541 663 5.7E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 SUPERFAMILY SSF52518 5 331 6.7E-122 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 SMART SM00861 355 525 8.1E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 6.0E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 Gene3D G3DSA:3.40.50.970 1 363 4.9E-129 T 28-03-2018 WM46_RS15000 dc3aa1e09c271a161d2fd52db1347f0e 663 SUPERFAMILY SSF52518 336 526 4.03E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS07580 a816643a90e107583eff00b0a41a4041 186 Pfam PF00419 Fimbrial protein 36 185 3.7E-13 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07580 a816643a90e107583eff00b0a41a4041 186 Gene3D G3DSA:2.60.40.1090 34 186 1.5E-28 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07580 a816643a90e107583eff00b0a41a4041 186 SUPERFAMILY SSF49401 35 186 1.74E-22 T 28-03-2018 IPR008966 Adhesion domain WM46_RS01760 9deee892f3f29acbc3bd5e33a47a950c 147 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 9 126 19.908 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 WM46_RS01760 9deee892f3f29acbc3bd5e33a47a950c 147 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 28 125 2.9E-31 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS23690 12bf40c20b086dc906b6e5913c0712b1 318 Gene3D G3DSA:3.40.50.1360 69 317 3.1E-34 T 28-03-2018 WM46_RS23690 12bf40c20b086dc906b6e5913c0712b1 318 SUPERFAMILY SSF100950 67 315 3.18E-57 T 28-03-2018 WM46_RS23690 12bf40c20b086dc906b6e5913c0712b1 318 Pfam PF04198 Putative sugar-binding domain 67 315 1.7E-68 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 WM46_RS23690 12bf40c20b086dc906b6e5913c0712b1 318 Gene3D G3DSA:1.10.10.10 1 63 2.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12265 db40835fbeec711bc24d2016b3df8bd8 218 SUPERFAMILY SSF52266 39 213 2.68E-51 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain WM46_RS12265 db40835fbeec711bc24d2016b3df8bd8 218 Gene3D G3DSA:3.40.50.1110 36 217 3.4E-38 T 28-03-2018 WM46_RS12265 db40835fbeec711bc24d2016b3df8bd8 218 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 40 50 - T 28-03-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 WM46_RS12265 db40835fbeec711bc24d2016b3df8bd8 218 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 43 197 2.9E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 SUPERFAMILY SSF48179 184 335 2.52E-57 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 6 326 38.531 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PIRSF PIRSF000114 1 336 7.9E-101 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 6.2E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 60 87 6.2E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 6.2E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 10 27 6.2E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 177 201 6.2E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 242 259 6.2E-42 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 192 213 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 SUPERFAMILY SSF51735 8 182 1.4E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 163 2.2E-50 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 Gene3D G3DSA:3.40.50.720 1 181 2.4E-39 T 28-03-2018 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 184 323 1.5E-52 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 WM46_RS20285 88b5fed751fe050607e8529df52d7ca1 339 Gene3D G3DSA:1.10.1040.10 193 339 1.8E-53 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 Gene3D G3DSA:3.90.226.10 11 287 1.2E-73 T 28-03-2018 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 249 258 4.7E-39 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 227 238 4.7E-39 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 141 4.7E-39 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 161 179 4.7E-39 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 198 215 4.7E-39 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 SUPERFAMILY SSF52096 23 284 1.19E-91 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 279 39.286 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 Pfam PF01039 Carboxyl transferase domain 92 240 1.4E-18 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 WM46_RS01580 25239d3bfaae353fc008858ab56dc0ca 304 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 281 9.2E-152 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 WM46_RS00535 3b8eb53f17a1b4504b33f65ea8fd71c1 280 Gene3D G3DSA:2.70.98.10 1 280 6.6E-44 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS00535 3b8eb53f17a1b4504b33f65ea8fd71c1 280 Pfam PF01263 Aldose 1-epimerase 5 277 1.2E-22 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 WM46_RS00535 3b8eb53f17a1b4504b33f65ea8fd71c1 280 SUPERFAMILY SSF74650 4 279 6.91E-43 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS04340 8b691bf52ca9f9605736a5e5648db31c 289 SUPERFAMILY SSF46689 1 80 5.73E-22 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS04340 8b691bf52ca9f9605736a5e5648db31c 289 Gene3D G3DSA:1.10.10.10 1 79 7.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04340 8b691bf52ca9f9605736a5e5648db31c 289 Pfam PF01380 SIS domain 124 252 2.9E-27 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS04340 8b691bf52ca9f9605736a5e5648db31c 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.8E-31 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS04340 8b691bf52ca9f9605736a5e5648db31c 289 Gene3D G3DSA:3.40.50.10490 80 287 1.3E-37 T 28-03-2018 WM46_RS04340 8b691bf52ca9f9605736a5e5648db31c 289 SUPERFAMILY SSF53697 94 279 2.22E-43 T 28-03-2018 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 Pfam PF00248 Aldo/keto reductase family 18 260 1.4E-47 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 SUPERFAMILY SSF51430 5 268 5.24E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 PIRSF PIRSF000097 1 269 2.4E-95 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 Gene3D G3DSA:3.20.20.100 1 274 1.2E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 PRINTS PR00069 Aldo-keto reductase signature 123 140 5.5E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 PRINTS PR00069 Aldo-keto reductase signature 91 109 5.5E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 PRINTS PR00069 Aldo-keto reductase signature 157 186 5.5E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 5.5E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 5.5E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS16030 39edd0e680d6fc21b649bd0a42285346 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS06635 aa782406c872a4452177070de94ee868 345 SMART SM00829 21 339 2.0E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS06635 aa782406c872a4452177070de94ee868 345 Pfam PF00107 Zinc-binding dehydrogenase 161 298 2.2E-18 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS06635 aa782406c872a4452177070de94ee868 345 SUPERFAMILY SSF50129 7 146 6.96E-45 T 28-03-2018 IPR011032 GroES-like WM46_RS06635 aa782406c872a4452177070de94ee868 345 Gene3D G3DSA:3.90.180.10 2 151 1.5E-31 T 28-03-2018 WM46_RS06635 aa782406c872a4452177070de94ee868 345 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 2.0E-42 T 28-03-2018 WM46_RS06635 aa782406c872a4452177070de94ee868 345 SUPERFAMILY SSF50129 290 340 2.78E-6 T 28-03-2018 IPR011032 GroES-like WM46_RS06635 aa782406c872a4452177070de94ee868 345 Gene3D G3DSA:3.40.50.720 152 282 1.7E-26 T 28-03-2018 WM46_RS06635 aa782406c872a4452177070de94ee868 345 SUPERFAMILY SSF51735 127 306 8.53E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23045 587a2945dc04b5a9f4a96e03152ddf4a 282 Gene3D G3DSA:3.40.50.720 1 282 8.1E-23 T 28-03-2018 WM46_RS23045 587a2945dc04b5a9f4a96e03152ddf4a 282 Pfam PF05368 NmrA-like family 2 220 3.9E-23 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 WM46_RS23045 587a2945dc04b5a9f4a96e03152ddf4a 282 SUPERFAMILY SSF51735 2 254 3.78E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS00040 5e962bc38347f6ad51c076454db73c46 419 Pfam PF03432 Relaxase/Mobilisation nuclease domain 11 263 3.5E-10 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 WM46_RS11605 9c23d5bd9363ec8a93a088fc36482245 334 Pfam PF01032 FecCD transport family 19 328 3.1E-90 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS11605 9c23d5bd9363ec8a93a088fc36482245 334 SUPERFAMILY SSF81345 8 329 3.66E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS11605 9c23d5bd9363ec8a93a088fc36482245 334 Gene3D G3DSA:1.10.3470.10 5 334 2.2E-61 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS07725 3ff5cc8dc5f543e5de2762df215bdb0e 225 SUPERFAMILY SSF161098 26 219 9.03E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07725 3ff5cc8dc5f543e5de2762df215bdb0e 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 211 3.2E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07725 3ff5cc8dc5f543e5de2762df215bdb0e 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 27 115 3.6E-12 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS07725 3ff5cc8dc5f543e5de2762df215bdb0e 225 Gene3D G3DSA:1.10.3720.10 22 223 1.4E-29 T 28-03-2018 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 Pfam PF00529 HlyD membrane-fusion protein of T1SS 36 346 1.2E-16 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 289 2.8E-13 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 SUPERFAMILY SSF111369 194 270 5.62E-8 T 28-03-2018 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 Gene3D G3DSA:2.40.50.100 60 138 3.9E-13 T 28-03-2018 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 Gene3D G3DSA:1.10.287.470 139 186 1.5E-6 T 28-03-2018 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 SUPERFAMILY SSF111369 56 112 6.54E-6 T 28-03-2018 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 TIGRFAM TIGR00998 8a0101: efflux pump membrane protein 20 345 4.8E-145 T 28-03-2018 IPR005694 Efflux pump membrane protein Emr GO:0006855|GO:0015238 WM46_RS25595 23ed7eeaf7e611f14317fde8ef537611 390 Gene3D G3DSA:2.40.50.100 209 365 3.3E-6 T 28-03-2018 WM46_RS17095 511c13509c2d5bac3344b5c948cc6312 90 SUPERFAMILY SSF52038 1 89 2.22E-27 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) WM46_RS17095 511c13509c2d5bac3344b5c948cc6312 90 Gene3D G3DSA:3.30.370.10 1 90 2.1E-19 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) WM46_RS17095 511c13509c2d5bac3344b5c948cc6312 90 Pfam PF01337 Barstar (barnase inhibitor) 5 79 1.2E-4 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) WM46_RS12945 0673615a7b43260013608f26eb73a56b 94 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 1 94 26.435 T 28-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase WM46_RS12945 0673615a7b43260013608f26eb73a56b 94 SUPERFAMILY SSF51182 1 94 4.62E-34 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS12945 0673615a7b43260013608f26eb73a56b 94 Gene3D G3DSA:2.60.120.10 3 93 1.7E-36 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS12945 0673615a7b43260013608f26eb73a56b 94 Pfam PF06865 Protein of unknown function (DUF1255) 3 93 9.8E-35 T 28-03-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase WM46_RS16820 865a070f093c933e31cc6641f22f1e27 209 Gene3D G3DSA:3.40.50.150 1 209 5.5E-59 T 28-03-2018 WM46_RS16820 865a070f093c933e31cc6641f22f1e27 209 Pfam PF01728 FtsJ-like methyltransferase 31 206 1.3E-58 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 WM46_RS16820 865a070f093c933e31cc6641f22f1e27 209 TIGRFAM TIGR00438 rrmJ: ribosomal RNA large subunit methyltransferase J 20 206 9.4E-97 T 28-03-2018 IPR004512 Ribosomal RNA methyltransferase E, gammaproteobacteria GO:0006364|GO:0016436 KEGG: 00564+2.1.1.16 WM46_RS16820 865a070f093c933e31cc6641f22f1e27 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 15 208 27.971 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 WM46_RS16820 865a070f093c933e31cc6641f22f1e27 209 PIRSF PIRSF005461 1 209 1.4E-82 T 28-03-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 WM46_RS16820 865a070f093c933e31cc6641f22f1e27 209 SUPERFAMILY SSF53335 31 208 7.4E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS01375 c2bbd651984287d8f4df4f29abdf69b3 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM46_RS01375 c2bbd651984287d8f4df4f29abdf69b3 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 101 1.3E-19 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM46_RS01375 c2bbd651984287d8f4df4f29abdf69b3 152 Gene3D G3DSA:3.40.140.10 1 152 9.3E-34 T 28-03-2018 WM46_RS01375 c2bbd651984287d8f4df4f29abdf69b3 152 SUPERFAMILY SSF53927 2 134 6.86E-36 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS02135 f223cd12df4e440cdf6f66387539df5b 87 Gene3D G3DSA:3.55.50.10 7 76 2.7E-5 T 28-03-2018 WM46_RS02135 f223cd12df4e440cdf6f66387539df5b 87 Pfam PF03927 NapD protein 5 81 5.9E-26 T 28-03-2018 IPR005623 Chaperone NapD, nitrate reductase assembly WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 Pfam PF02082 Transcriptional regulator 1 83 5.4E-27 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 Hamap MF_01176 HTH-type transcriptional regulator IscR [iscR]. 1 163 46.465 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 SUPERFAMILY SSF46785 2 133 9.6E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 1.9E-46 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 4.4E-66 T 28-03-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 WM46_RS00615 e85e635d9f2cfd73849549e6cab8419b 163 Gene3D G3DSA:1.10.10.10 1 140 7.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24835 33750ef5a780719cb2d229206b0a8fcd 346 SUPERFAMILY SSF51430 1 344 6.81E-106 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS24835 33750ef5a780719cb2d229206b0a8fcd 346 Pfam PF00248 Aldo/keto reductase family 16 337 7.4E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS24835 33750ef5a780719cb2d229206b0a8fcd 346 PRINTS PR00069 Aldo-keto reductase signature 164 181 2.3E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS24835 33750ef5a780719cb2d229206b0a8fcd 346 PRINTS PR00069 Aldo-keto reductase signature 116 134 2.3E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS24835 33750ef5a780719cb2d229206b0a8fcd 346 Gene3D G3DSA:3.20.20.100 1 346 1.8E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS17660 d8ecbe2a102fac5795956435d0bf7e7b 72 SUPERFAMILY SSF118001 1 71 1.44E-29 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 WM46_RS17660 d8ecbe2a102fac5795956435d0bf7e7b 72 PIRSF PIRSF006169 1 72 1.6E-37 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 WM46_RS17660 d8ecbe2a102fac5795956435d0bf7e7b 72 Hamap MF_00690 UPF0270 protein YheU [yheU]. 1 70 25.712 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 WM46_RS17660 d8ecbe2a102fac5795956435d0bf7e7b 72 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 68 2.0E-30 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 WM46_RS17660 d8ecbe2a102fac5795956435d0bf7e7b 72 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 69 2.4E-35 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 WM46_RS17660 d8ecbe2a102fac5795956435d0bf7e7b 72 Gene3D G3DSA:1.10.10.610 1 71 1.5E-36 T 28-03-2018 IPR010648 Uncharacterised protein family UPF0270 WM46_RS05705 db594147136289dd8505d3004532b587 302 Pfam PF01734 Patatin-like phospholipase 8 165 6.1E-23 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM46_RS05705 db594147136289dd8505d3004532b587 302 Gene3D G3DSA:3.40.1090.10 2 280 3.5E-40 T 28-03-2018 WM46_RS05705 db594147136289dd8505d3004532b587 302 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 28-03-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 WM46_RS05705 db594147136289dd8505d3004532b587 302 SUPERFAMILY SSF52151 1 296 3.14E-58 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 WM46_RS04945 8937699fab567ef20b8f7346894d7960 152 ProDom PD091196 MEMBRANE UPF0266 TRANSMEMBRANE INNER YOBD PLU2700 LMO0779 PM0830 YPO1755/Y2554/YP1637 LIN0773 22 148 4.0E-63 T 28-03-2018 IPR009328 Protein of unknown function DUF986 WM46_RS04945 8937699fab567ef20b8f7346894d7960 152 Pfam PF06173 Protein of unknown function (DUF986) 4 151 5.8E-63 T 28-03-2018 IPR009328 Protein of unknown function DUF986 WM46_RS04945 8937699fab567ef20b8f7346894d7960 152 Hamap MF_01071 UPF0266 membrane protein YobD [yobD]. 1 152 31.43 T 28-03-2018 IPR009328 Protein of unknown function DUF986 WM46_RS04945 8937699fab567ef20b8f7346894d7960 152 PIRSF PIRSF020687 1 152 5.2E-67 T 28-03-2018 IPR009328 Protein of unknown function DUF986 WM46_RS12600 825d4b833e4766458026086b20205127 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 7 118 2.8E-36 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM46_RS12600 825d4b833e4766458026086b20205127 132 SUPERFAMILY SSF54637 3 129 7.62E-39 T 28-03-2018 IPR029069 HotDog domain WM46_RS12600 825d4b833e4766458026086b20205127 132 Gene3D G3DSA:3.10.129.10 1 132 1.7E-35 T 28-03-2018 WM46_RS12600 825d4b833e4766458026086b20205127 132 Pfam PF13279 Thioesterase-like superfamily 11 125 1.5E-16 T 28-03-2018 WM46_RS12600 825d4b833e4766458026086b20205127 132 PIRSF PIRSF003230 1 132 2.1E-21 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 WM46_RS07890 306b705c8807cd7bae70eb6f7f82e258 118 Gene3D G3DSA:1.10.3100.10 1 118 3.0E-14 T 28-03-2018 IPR027910 YdiL-like domain WM46_RS07890 306b705c8807cd7bae70eb6f7f82e258 118 SUPERFAMILY SSF47413 1 118 2.42E-40 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS07890 306b705c8807cd7bae70eb6f7f82e258 118 Pfam PF08965 Domain of unknown function (DUF1870) 1 118 1.5E-47 T 28-03-2018 IPR015060 Protein of unknown function DUF1870 WM46_RS05170 6e5a5e5a767e21e1f83042df9e91042c 510 Pfam PF04293 SpoVR like protein 19 450 6.0E-177 T 28-03-2018 IPR007390 Sporulation stage V, protein R WM46_RS10990 20b8e505366d7982106809571594df2c 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 230 2.3E-91 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10990 20b8e505366d7982106809571594df2c 238 SUPERFAMILY SSF54292 1 106 7.36E-30 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS10990 20b8e505366d7982106809571594df2c 238 Gene3D G3DSA:3.10.20.30 1 106 3.5E-32 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS10990 20b8e505366d7982106809571594df2c 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 111 9.0E-31 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS10990 20b8e505366d7982106809571594df2c 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS10990 20b8e505366d7982106809571594df2c 238 Gene3D G3DSA:1.10.1060.10 107 238 3.6E-29 T 28-03-2018 WM46_RS10990 20b8e505366d7982106809571594df2c 238 SUPERFAMILY SSF46548 107 236 1.45E-39 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS10990 20b8e505366d7982106809571594df2c 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 3.5E-10 T 28-03-2018 WM46_RS24300 9cc0530078e58cd111ba2cc4ff670827 438 SUPERFAMILY SSF51556 75 378 3.49E-103 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS24300 9cc0530078e58cd111ba2cc4ff670827 438 Gene3D G3DSA:3.20.20.140 84 377 1.6E-69 T 28-03-2018 WM46_RS24300 9cc0530078e58cd111ba2cc4ff670827 438 Gene3D G3DSA:2.30.40.10 6 83 9.5E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24300 9cc0530078e58cd111ba2cc4ff670827 438 SUPERFAMILY SSF51338 32 90 5.55E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24300 9cc0530078e58cd111ba2cc4ff670827 438 Pfam PF01979 Amidohydrolase family 72 434 4.3E-82 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS24300 9cc0530078e58cd111ba2cc4ff670827 438 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 32 431 9.2E-188 T 28-03-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 WM46_RS03875 34e332962cf88e9d62c84e8a873427ab 472 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 106 7.1E-19 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 WM46_RS03875 34e332962cf88e9d62c84e8a873427ab 472 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 226 456 3.6E-60 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 WM46_RS03875 34e332962cf88e9d62c84e8a873427ab 472 Gene3D G3DSA:1.20.1480.30 399 472 3.4E-4 T 28-03-2018 WM46_RS03875 34e332962cf88e9d62c84e8a873427ab 472 Pfam PF07196 Flagellin hook IN motif 130 186 2.3E-11 T 28-03-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 WM46_RS08930 732044e9bd041d2d23b740c49a98d1fb 177 SUPERFAMILY SSF52949 3 172 3.2E-66 T 28-03-2018 WM46_RS08930 732044e9bd041d2d23b740c49a98d1fb 177 Gene3D G3DSA:3.40.220.10 1 177 1.5E-72 T 28-03-2018 WM46_RS08930 732044e9bd041d2d23b740c49a98d1fb 177 Hamap MF_01205 O-acetyl-ADP-ribose deacetylase [ymdB]. 2 172 47.991 T 28-03-2018 IPR024900 O-acetyl-ADP-ribose deacetylase WM46_RS08930 732044e9bd041d2d23b740c49a98d1fb 177 Pfam PF01661 Macro domain 21 137 4.1E-44 T 28-03-2018 IPR002589 Macro domain WM46_RS08930 732044e9bd041d2d23b740c49a98d1fb 177 SMART SM00506 4 137 2.3E-55 T 28-03-2018 IPR002589 Macro domain WM46_RS22870 c66aab26233be366c06e405ba21804dd 443 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 193 412 7.9E-49 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM46_RS22870 c66aab26233be366c06e405ba21804dd 443 SUPERFAMILY SSF53187 339 416 1.82E-53 T 28-03-2018 WM46_RS22870 c66aab26233be366c06e405ba21804dd 443 SUPERFAMILY SSF53187 191 287 1.82E-53 T 28-03-2018 WM46_RS22870 c66aab26233be366c06e405ba21804dd 443 Gene3D G3DSA:3.40.630.40 188 420 1.2E-58 T 28-03-2018 WM46_RS22870 c66aab26233be366c06e405ba21804dd 443 SMART SM00646 253 412 5.7E-76 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 Pfam PF00005 ABC transporter 22 169 3.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 Gene3D G3DSA:3.30.70.260 257 339 1.2E-20 T 28-03-2018 WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 SMART SM00382 30 218 9.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 Gene3D G3DSA:3.40.50.300 1 256 4.6E-78 T 28-03-2018 WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 SMART SM00930 262 337 1.8E-22 T 28-03-2018 IPR018449 NIL domain WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 Pfam PF09383 NIL domain 264 336 1.6E-17 T 28-03-2018 IPR018449 NIL domain WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 SUPERFAMILY SSF52540 1 240 1.82E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS07800 8b6ddb84467887038de07e49f93dd148 340 SUPERFAMILY SSF55021 262 339 7.78E-19 T 28-03-2018 WM46_RS13775 19e594a0ea1ad913e81c799ee1e6aa0f 392 Pfam PF07690 Major Facilitator Superfamily 9 318 1.4E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS13775 19e594a0ea1ad913e81c799ee1e6aa0f 392 Gene3D G3DSA:1.20.1250.20 3 187 4.6E-24 T 28-03-2018 WM46_RS13775 19e594a0ea1ad913e81c799ee1e6aa0f 392 Gene3D G3DSA:1.20.1250.20 188 381 2.5E-23 T 28-03-2018 WM46_RS13775 19e594a0ea1ad913e81c799ee1e6aa0f 392 SUPERFAMILY SSF103473 3 385 3.66E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS02560 9fb6a4280b4392e0ccd07879c3ddce8c 184 SUPERFAMILY SSF55729 14 177 2.23E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS02560 9fb6a4280b4392e0ccd07879c3ddce8c 184 Pfam PF13420 Acetyltransferase (GNAT) domain 14 169 1.5E-18 T 28-03-2018 WM46_RS02560 9fb6a4280b4392e0ccd07879c3ddce8c 184 Gene3D G3DSA:3.40.630.30 9 181 9.9E-34 T 28-03-2018 WM46_RS07710 7418da5c060046a8cce1c670fd76b219 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 261 4.5E-60 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS07710 7418da5c060046a8cce1c670fd76b219 277 SUPERFAMILY SSF53850 14 262 3.83E-68 T 28-03-2018 WM46_RS07710 7418da5c060046a8cce1c670fd76b219 277 SMART SM00062 42 263 1.7E-67 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS07710 7418da5c060046a8cce1c670fd76b219 277 SMART SM00079 42 262 1.5E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 WM46_RS07710 7418da5c060046a8cce1c670fd76b219 277 Gene3D G3DSA:3.40.190.10 31 184 1.8E-44 T 28-03-2018 WM46_RS07710 7418da5c060046a8cce1c670fd76b219 277 Gene3D G3DSA:3.40.190.10 185 273 5.5E-12 T 28-03-2018 WM46_RS05925 e50cc18476c22ef0cd54e89b9506f565 254 SMART SM00014 76 227 1.3E-38 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS05925 e50cc18476c22ef0cd54e89b9506f565 254 Gene3D G3DSA:1.20.144.10 5 250 1.2E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS05925 e50cc18476c22ef0cd54e89b9506f565 254 SUPERFAMILY SSF48317 13 113 3.4E-31 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS05925 e50cc18476c22ef0cd54e89b9506f565 254 SUPERFAMILY SSF48317 145 233 3.4E-31 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS05925 e50cc18476c22ef0cd54e89b9506f565 254 Pfam PF01569 PAP2 superfamily 80 232 8.0E-34 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase WM46_RS16875 fca8a1955ffd66d59c4678b998c6d2ee 97 Gene3D G3DSA:3.30.300.90 10 96 2.6E-26 T 28-03-2018 WM46_RS16875 fca8a1955ffd66d59c4678b998c6d2ee 97 SUPERFAMILY SSF82657 13 95 5.1E-29 T 28-03-2018 IPR002634 BolA protein WM46_RS16875 fca8a1955ffd66d59c4678b998c6d2ee 97 PIRSF PIRSF003113 4 96 6.2E-23 T 28-03-2018 IPR002634 BolA protein WM46_RS16875 fca8a1955ffd66d59c4678b998c6d2ee 97 Pfam PF01722 BolA-like protein 30 87 8.3E-15 T 28-03-2018 IPR002634 BolA protein WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 SUPERFAMILY SSF103473 14 419 2.62E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 Gene3D G3DSA:1.20.1250.20 231 430 2.4E-21 T 28-03-2018 WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 Gene3D G3DSA:1.20.1250.20 9 225 1.8E-26 T 28-03-2018 WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 291 308 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 20 410 5.0E-144 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 Pfam PF07690 Major Facilitator Superfamily 19 376 3.8E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS11190 42cb01901de447aa88f58394ebfdda4e 431 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 142 2.6E-65 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 1.2E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 SMART SM00649 9 141 3.0E-84 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.562 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 Gene3D G3DSA:1.10.10.250 73 141 6.7E-24 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 SUPERFAMILY SSF54747 3 73 4.97E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 28-03-2018 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 Gene3D G3DSA:3.30.1550.10 3 72 9.6E-35 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 4.5E-24 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 WM46_RS21165 c863f67b8034555e4ecb27dc46716448 142 SUPERFAMILY SSF46906 68 141 8.77E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 6 533 6.0E-184 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 Pfam PF00664 ABC transporter transmembrane region 67 287 1.3E-9 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 Gene3D G3DSA:3.40.50.300 330 571 7.5E-73 T 28-03-2018 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 Pfam PF00005 ABC transporter 356 502 1.2E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 SMART SM00382 365 549 6.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 SUPERFAMILY SSF90123 8 327 7.32E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 Gene3D G3DSA:1.20.1560.10 1 329 3.7E-33 T 28-03-2018 WM46_RS09965 b224afc58c5b65e72c1e6ddc25169b3b 573 SUPERFAMILY SSF52540 333 569 2.77E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08220 67d7067e18d541b0ca9a8af9dcf25335 210 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS08220 67d7067e18d541b0ca9a8af9dcf25335 210 SMART SM00382 26 210 4.7E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS08220 67d7067e18d541b0ca9a8af9dcf25335 210 Pfam PF00005 ABC transporter 20 161 2.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS08220 67d7067e18d541b0ca9a8af9dcf25335 210 Gene3D G3DSA:3.40.50.300 1 204 1.2E-43 T 28-03-2018 WM46_RS08220 67d7067e18d541b0ca9a8af9dcf25335 210 SUPERFAMILY SSF52540 1 197 9.74E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 1 738 34.22 T 28-03-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 465 8.5E-135 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 SUPERFAMILY SSF56719 28 479 7.19E-154 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 593 631 1.3E-4 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 641 675 5.7E-8 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Gene3D G3DSA:1.10.268.10 341 480 3.7E-46 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Gene3D G3DSA:2.120.10.90 492 737 1.7E-44 T 28-03-2018 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Gene3D G3DSA:3.30.1360.40 235 328 1.8E-23 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 Gene3D G3DSA:3.90.199.10 31 212 1.9E-74 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 5 737 0.0 T 28-03-2018 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 SMART SM00434 8 458 6.7E-240 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16050 1bfa64444dc9a6cd3e4bc6a86042d83f 752 SUPERFAMILY SSF101904 494 735 6.15E-51 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal WM46_RS05545 45e5414398115d25235c384c92d515be 207 SUPERFAMILY SSF89392 34 206 1.45E-55 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX WM46_RS05545 45e5414398115d25235c384c92d515be 207 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 6 206 29.63 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 WM46_RS05545 45e5414398115d25235c384c92d515be 207 Pfam PF03550 Outer membrane lipoprotein LolB 50 204 1.4E-49 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 WM46_RS05545 45e5414398115d25235c384c92d515be 207 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 5 206 2.3E-95 T 28-03-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 WM46_RS05545 45e5414398115d25235c384c92d515be 207 Gene3D G3DSA:2.50.20.10 30 207 6.2E-55 T 28-03-2018 WM46_RS13960 e45a157c6d4649a9c6449d4ec38da8ea 185 SUPERFAMILY SSF55194 2 184 7.98E-72 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 WM46_RS13960 e45a157c6d4649a9c6449d4ec38da8ea 185 Pfam PF01765 Ribosome recycling factor 20 183 2.5E-63 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 WM46_RS13960 e45a157c6d4649a9c6449d4ec38da8ea 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 2.2E-81 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 WM46_RS13960 e45a157c6d4649a9c6449d4ec38da8ea 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.596 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 WM46_RS13960 e45a157c6d4649a9c6449d4ec38da8ea 185 Gene3D G3DSA:1.10.132.20 2 74 7.1E-10 T 28-03-2018 WM46_RS13960 e45a157c6d4649a9c6449d4ec38da8ea 185 Gene3D G3DSA:1.10.132.20 75 184 1.3E-36 T 28-03-2018 WM46_RS08215 a60186f8bcf03ed91ccc591ceb9e28a9 511 SUPERFAMILY SSF161098 7 255 2.62E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08215 a60186f8bcf03ed91ccc591ceb9e28a9 511 SUPERFAMILY SSF161098 306 496 4.06E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08215 a60186f8bcf03ed91ccc591ceb9e28a9 511 Gene3D G3DSA:1.10.3720.10 2 267 4.5E-16 T 28-03-2018 WM46_RS08215 a60186f8bcf03ed91ccc591ceb9e28a9 511 Gene3D G3DSA:1.10.3720.10 282 506 2.1E-13 T 28-03-2018 WM46_RS08215 a60186f8bcf03ed91ccc591ceb9e28a9 511 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 349 491 4.6E-7 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS23110 91162d5ae5d2abbb12a61f3bcf3ca1dd 384 SUPERFAMILY SSF55347 131 277 5.89E-31 T 28-03-2018 WM46_RS23110 91162d5ae5d2abbb12a61f3bcf3ca1dd 384 Gene3D G3DSA:3.40.50.720 1 139 1.2E-35 T 28-03-2018 WM46_RS23110 91162d5ae5d2abbb12a61f3bcf3ca1dd 384 Gene3D G3DSA:3.30.360.10 140 359 5.3E-38 T 28-03-2018 WM46_RS23110 91162d5ae5d2abbb12a61f3bcf3ca1dd 384 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 248 1.6E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS23110 91162d5ae5d2abbb12a61f3bcf3ca1dd 384 SUPERFAMILY SSF51735 2 154 8.22E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS23110 91162d5ae5d2abbb12a61f3bcf3ca1dd 384 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 125 2.2E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 Gene3D G3DSA:1.10.3860.10 1 400 1.1E-75 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 SUPERFAMILY SSF118215 13 393 2.62E-77 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 Pfam PF00375 Sodium:dicarboxylate symporter family 13 392 5.3E-78 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 PRINTS PR00173 Glutamate-aspartate symporter signature 347 367 4.8E-9 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 4.8E-9 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 PRINTS PR00173 Glutamate-aspartate symporter signature 285 311 4.8E-9 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS23800 9ffc1c209ad263fcf962eee84e45709d 412 PRINTS PR00173 Glutamate-aspartate symporter signature 183 202 4.8E-9 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 Pfam PF02119 Flagellar P-ring protein 21 364 4.7E-138 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 21 36 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 36 51 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 251 263 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 121 139 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 104 121 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 187 205 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 161 179 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 56 71 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 PRINTS PR01010 Flagellar P-ring protein signature 82 101 2.1E-92 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08755 f627ebce8df04b399b7656ca13a08f1b 365 Hamap MF_00416 Flagellar P-ring protein [flgI]. 1 365 39.715 T 28-03-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 WM46_RS08540 ce5e68d44dccf5ab2af2e6dda2898111 303 ProSitePatterns PS01125 ROK family signature. 130 157 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS08540 ce5e68d44dccf5ab2af2e6dda2898111 303 Gene3D G3DSA:3.30.420.40 113 303 5.9E-49 T 28-03-2018 WM46_RS08540 ce5e68d44dccf5ab2af2e6dda2898111 303 Pfam PF00480 ROK family 2 300 2.1E-68 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS08540 ce5e68d44dccf5ab2af2e6dda2898111 303 SUPERFAMILY SSF53067 1 300 4.31E-60 T 28-03-2018 WM46_RS08540 ce5e68d44dccf5ab2af2e6dda2898111 303 Gene3D G3DSA:3.30.420.40 1 112 2.0E-25 T 28-03-2018 WM46_RS08540 ce5e68d44dccf5ab2af2e6dda2898111 303 Hamap MF_01271 N-acetyl-D-glucosamine kinase [nagK]. 1 303 65.992 T 28-03-2018 IPR023505 N-acetyl-D-glucosamine kinase GO:0045127 KEGG: 00520+2.7.1.59|MetaCyc: PWY-6517|MetaCyc: PWY-6906 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 287 3.5E-146 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.428 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 SUPERFAMILY SSF52210 123 288 2.62E-57 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 SMART SM00881 4 100 3.3E-37 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.5E-39 T 28-03-2018 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.5E-39 T 28-03-2018 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.5E-39 T 28-03-2018 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.5E-39 T 28-03-2018 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 Pfam PF00549 CoA-ligase 151 271 5.4E-20 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 SUPERFAMILY SSF51735 1 122 1.49E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 PIRSF PIRSF001553 1 289 1.0E-134 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 Gene3D G3DSA:3.40.50.261 120 289 2.1E-56 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 Pfam PF02629 CoA binding domain 6 99 2.3E-31 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS10970 010d9de42206f6b82642f195ad9a5b01 289 Gene3D G3DSA:3.40.50.720 1 119 1.7E-44 T 28-03-2018 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 Gene3D G3DSA:3.90.1150.10 20 112 7.6E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 Gene3D G3DSA:3.90.1150.10 289 469 2.5E-67 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 SUPERFAMILY SSF53383 6 471 5.02E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 260 278 - T 28-03-2018 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 Pfam PF01212 Beta-eliminating lyase 49 437 2.8E-90 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 TIGRFAM TIGR02617 tnaA_trp_ase: tryptophanase 5 471 1.8E-296 T 28-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 PIRSF PIRSF001386 3 471 5.7E-202 T 28-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 WM46_RS19610 f9618c35975cfb3707cd05d31e8eb5a0 471 Hamap MF_00544 Tryptophanase [tnaA]. 4 471 99.99 T 28-03-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 Gene3D G3DSA:1.20.5.1150 16 52 1.0E-17 T 28-03-2018 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 Pfam PF01165 Ribosomal protein S21 4 56 6.3E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.283 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 2.8E-17 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 2.8E-17 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 2.8E-17 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 2.8E-17 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 4.1E-24 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS16300 e0f63aa874b218a4c9d359851efe3e90 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 56 1.0E-15 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 241 261 2.4E-7 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 125 139 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 173 189 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 93 108 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 215 231 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 56 73 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 241 259 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 197 212 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 PRINTS PR01714 Ferric iron reductase signature 16 32 4.4E-70 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 TIGRFAM TIGR03951 Fe_III_red_FhuF: siderophore-iron reductase FhuF 87 262 1.7E-67 T 28-03-2018 IPR008090 Ferric iron reductase WM46_RS24010 6cc121a27b09a4547dda7cb29c68e405 262 Pfam PF06276 Ferric iron reductase FhuF-like transporter 93 237 1.4E-30 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 SMART SM00347 31 132 1.1E-33 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 Gene3D G3DSA:1.10.10.10 7 144 6.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 2.6E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 2.6E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 2.6E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 2.6E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 SUPERFAMILY SSF46785 5 142 3.34E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07075 77664324a87f17371a872a2c46a2db96 144 Pfam PF01047 MarR family 38 96 4.8E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS19965 2c604b6cc402d2e9cedf0c784913b7d8 272 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 272 9.7E-148 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS19965 2c604b6cc402d2e9cedf0c784913b7d8 272 SUPERFAMILY SSF53850 34 272 7.97E-75 T 28-03-2018 WM46_RS19965 2c604b6cc402d2e9cedf0c784913b7d8 272 Gene3D G3DSA:3.40.190.10 128 272 8.5E-46 T 28-03-2018 WM46_RS19965 2c604b6cc402d2e9cedf0c784913b7d8 272 Gene3D G3DSA:3.40.190.10 33 127 2.6E-16 T 28-03-2018 WM46_RS19965 2c604b6cc402d2e9cedf0c784913b7d8 272 PIRSF PIRSF002854 4 272 3.5E-94 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS19965 2c604b6cc402d2e9cedf0c784913b7d8 272 Pfam PF03180 NLPA lipoprotein 34 272 4.8E-92 T 28-03-2018 IPR004872 Lipoprotein NlpA family WM46_RS16230 159739bb080ab563fefba6277840bd6b 121 SUPERFAMILY SSF55620 1 115 7.23E-36 T 28-03-2018 WM46_RS16230 159739bb080ab563fefba6277840bd6b 121 TIGRFAM TIGR00526 folB_dom: FolB domain 1 118 1.7E-41 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS16230 159739bb080ab563fefba6277840bd6b 121 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 4 114 4.5E-27 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS16230 159739bb080ab563fefba6277840bd6b 121 Pfam PF02152 Dihydroneopterin aldolase 4 113 2.7E-31 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS16230 159739bb080ab563fefba6277840bd6b 121 SMART SM00905 4 114 6.3E-46 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS16230 159739bb080ab563fefba6277840bd6b 121 Gene3D G3DSA:3.30.1130.10 1 121 1.9E-35 T 28-03-2018 WM46_RS24995 2011e58c1d64f1dbae8195183304c8ed 140 Gene3D G3DSA:3.40.1650.10 1 140 7.2E-48 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS24995 2011e58c1d64f1dbae8195183304c8ed 140 Pfam PF05025 RbsD / FucU transport protein family 3 139 2.7E-35 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS24995 2011e58c1d64f1dbae8195183304c8ed 140 SUPERFAMILY SSF102546 1 139 2.62E-38 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS24995 2011e58c1d64f1dbae8195183304c8ed 140 Hamap MF_01662 L-fucose mutarotase [fucU]. 1 140 46.291 T 28-03-2018 IPR023751 L-fucose mutarotase GO:0016854|GO:0042354|GO:0042806 WM46_RS17730 25de191d06709258d8346796a17dc234 108 SUPERFAMILY SSF50022 1 107 2.44E-34 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM46_RS17730 25de191d06709258d8346796a17dc234 108 Gene3D G3DSA:2.102.10.10 1 108 9.2E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 WM46_RS17730 25de191d06709258d8346796a17dc234 108 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 3 107 1.5E-39 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 WM46_RS17730 25de191d06709258d8346796a17dc234 108 Pfam PF13806 Rieske-like [2Fe-2S] domain 3 106 3.6E-39 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 WM46_RS03020 6dcc27b9f030145443251f791a695a0a 196 SUPERFAMILY SSF52317 3 195 1.23E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS03020 6dcc27b9f030145443251f791a695a0a 196 Gene3D G3DSA:3.40.50.880 1 196 2.1E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS03020 6dcc27b9f030145443251f791a695a0a 196 Pfam PF00117 Glutamine amidotransferase class-I 7 194 3.6E-18 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS03020 6dcc27b9f030145443251f791a695a0a 196 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 196 33.598 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 WM46_RS03020 6dcc27b9f030145443251f791a695a0a 196 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 3 196 7.9E-74 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 WM46_RS03020 6dcc27b9f030145443251f791a695a0a 196 PIRSF PIRSF000495 1 196 4.6E-63 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 WM46_RS14005 69d69cff8357877d9ad8f5394d8f4eeb 385 Gene3D G3DSA:3.30.450.40 27 165 0.0016 T 28-03-2018 IPR029016 GAF domain-like WM46_RS14005 69d69cff8357877d9ad8f5394d8f4eeb 385 Pfam PF05651 Putative sugar diacid recognition 6 138 5.3E-49 T 28-03-2018 IPR008599 Putative sugar diacid recognition WM46_RS14005 69d69cff8357877d9ad8f5394d8f4eeb 385 Gene3D G3DSA:1.10.10.60 308 359 2.1E-5 T 28-03-2018 WM46_RS14005 69d69cff8357877d9ad8f5394d8f4eeb 385 Pfam PF13556 PucR C-terminal helix-turn-helix domain 323 380 3.4E-22 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain WM46_RS23490 8bd675b327bac808492c3e3931035a29 313 Pfam PF07582 AP endonuclease family 2 C terminus 269 309 1.3E-10 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal WM46_RS23490 8bd675b327bac808492c3e3931035a29 313 SUPERFAMILY SSF51658 1 307 4.01E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS23490 8bd675b327bac808492c3e3931035a29 313 Gene3D G3DSA:3.20.20.150 1 313 2.1E-49 T 28-03-2018 WM46_RS23490 8bd675b327bac808492c3e3931035a29 313 Pfam PF01261 Xylose isomerase-like TIM barrel 19 263 1.6E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 SMART SM00382 18 207 9.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 SMART SM00382 272 468 1.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 Gene3D G3DSA:3.40.50.300 242 481 3.7E-39 T 28-03-2018 WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 SUPERFAMILY SSF52540 3 213 2.72E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 Pfam PF00005 ABC transporter 9 159 9.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 Pfam PF00005 ABC transporter 264 419 2.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 Gene3D G3DSA:3.40.50.300 1 217 5.3E-54 T 28-03-2018 WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS11660 705e34d5d1273e9417af60d1edce5607 491 SUPERFAMILY SSF52540 245 471 3.49E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00255 325353c7fdb51c672df0d18fd19611a9 112 SUPERFAMILY SSF69754 3 109 1.24E-33 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS00255 325353c7fdb51c672df0d18fd19611a9 112 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 91 4.5E-22 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS00255 325353c7fdb51c672df0d18fd19611a9 112 Gene3D G3DSA:3.30.160.100 2 92 2.6E-27 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS00255 325353c7fdb51c672df0d18fd19611a9 112 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 97 4.8E-35 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 SUPERFAMILY SSF53187 153 471 4.39E-98 T 28-03-2018 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 PRINTS PR00481 Cytosol aminopeptidase signature 258 279 1.1E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 PRINTS PR00481 Cytosol aminopeptidase signature 236 253 1.1E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 PRINTS PR00481 Cytosol aminopeptidase signature 317 337 1.1E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 PRINTS PR00481 Cytosol aminopeptidase signature 347 362 1.1E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 PRINTS PR00481 Cytosol aminopeptidase signature 295 316 1.1E-43 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 321 328 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 161 465 2.3E-102 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS00800 3aac06baa6d9728f7a046d8748c0e18b 477 Gene3D G3DSA:3.40.630.10 144 476 3.1E-110 T 28-03-2018 WM46_RS09245 ea67c6cfb09cbde3a58cf34cf30834fc 101 Gene3D G3DSA:1.10.1660.10 1 101 2.7E-9 T 28-03-2018 WM46_RS09245 ea67c6cfb09cbde3a58cf34cf30834fc 101 Hamap MF_01155 Chaperone modulatory protein CbpM [cbpM]. 1 97 25.472 T 28-03-2018 IPR022835 Chaperone modulatory protein CbpM WM46_RS09245 ea67c6cfb09cbde3a58cf34cf30834fc 101 Pfam PF13591 MerR HTH family regulatory protein 8 92 1.6E-25 T 28-03-2018 WM46_RS24660 6e3b825304a710f1a599f247cc9ce817 174 SUPERFAMILY SSF109604 2 171 5.49E-36 T 28-03-2018 WM46_RS24660 6e3b825304a710f1a599f247cc9ce817 174 Gene3D G3DSA:1.10.3210.10 1 174 7.3E-23 T 28-03-2018 WM46_RS12355 569a6b03c41c071871f97fe7ec8b7992 323 SUPERFAMILY SSF53474 28 318 1.45E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS12355 569a6b03c41c071871f97fe7ec8b7992 323 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 159 171 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site WM46_RS12355 569a6b03c41c071871f97fe7ec8b7992 323 Hamap MF_01958 Acetyl esterase [aes]. 1 319 70.031 T 28-03-2018 IPR023508 Acetyl esterase GO:0005737|GO:0052689 WM46_RS12355 569a6b03c41c071871f97fe7ec8b7992 323 Pfam PF07859 alpha/beta hydrolase fold 87 295 3.6E-50 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 WM46_RS12355 569a6b03c41c071871f97fe7ec8b7992 323 Gene3D G3DSA:3.40.50.1820 1 323 4.6E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 Gene3D G3DSA:3.40.50.300 8 253 1.9E-52 T 28-03-2018 WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 SMART SM00382 288 480 1.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 SMART SM00382 36 224 9.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 Gene3D G3DSA:3.40.50.300 277 490 9.0E-40 T 28-03-2018 WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 SUPERFAMILY SSF52540 10 230 9.86E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 ProSitePatterns PS00211 ABC transporters family signature. 404 418 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 Pfam PF00005 ABC transporter 280 431 5.0E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 Pfam PF00005 ABC transporter 27 169 1.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS23685 91b6c1ae756d1c359304b0d428fc8794 517 SUPERFAMILY SSF52540 279 480 6.93E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17370 e6e22341c57cdd3f5ab0db2d7b7d1f9a 374 Gene3D G3DSA:3.40.50.450 109 252 1.8E-33 T 28-03-2018 WM46_RS17370 e6e22341c57cdd3f5ab0db2d7b7d1f9a 374 SUPERFAMILY SSF102405 77 283 7.1E-37 T 28-03-2018 WM46_RS17370 e6e22341c57cdd3f5ab0db2d7b7d1f9a 374 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 65 283 1.0E-80 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 WM46_RS17370 e6e22341c57cdd3f5ab0db2d7b7d1f9a 374 Pfam PF02481 DNA recombination-mediator protein A 68 274 3.9E-70 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 WM46_RS17370 e6e22341c57cdd3f5ab0db2d7b7d1f9a 374 Gene3D G3DSA:1.10.10.10 272 362 2.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21860 65a084f874b872826ae5920f3538536c 282 PIRSF PIRSF011468 1 282 4.8E-169 T 28-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS21860 65a084f874b872826ae5920f3538536c 282 Pfam PF06007 Phosphonate metabolism protein PhnJ 7 278 3.1E-149 T 28-03-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS22050 00e05a83c141d9219023b2afa2c67b97 149 Gene3D G3DSA:2.60.40.1090 1 149 4.3E-27 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22050 00e05a83c141d9219023b2afa2c67b97 149 Pfam PF00419 Fimbrial protein 6 148 3.9E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22050 00e05a83c141d9219023b2afa2c67b97 149 SUPERFAMILY SSF49401 1 148 7.46E-33 T 28-03-2018 IPR008966 Adhesion domain WM46_RS03720 d836f1e817f834c3db74c3f4a7b52c31 232 SUPERFAMILY SSF109604 3 215 2.76E-57 T 28-03-2018 WM46_RS03720 d836f1e817f834c3db74c3f4a7b52c31 232 Pfam PF01966 HD domain 29 131 1.9E-11 T 28-03-2018 IPR006674 HD domain WM46_RS03720 d836f1e817f834c3db74c3f4a7b52c31 232 Gene3D G3DSA:1.10.3210.10 6 229 1.1E-15 T 28-03-2018 WM46_RS03720 d836f1e817f834c3db74c3f4a7b52c31 232 SMART SM00471 22 141 1.1E-6 T 28-03-2018 IPR003607 HD/PDEase domain WM46_RS03745 69a41a2318259f1cd022e9596da9de33 60 Pfam PF09926 Uncharacterized small protein (DUF2158) 9 45 3.2E-7 T 28-03-2018 IPR019226 Protein of unknown function DUF2158 WM46_RS00950 b0e90500ec76cdfabf867171ca94045f 111 PIRSF PIRSF012296 1 111 2.8E-57 T 28-03-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 WM46_RS00950 b0e90500ec76cdfabf867171ca94045f 111 SMART SM00877 39 111 1.3E-12 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS00950 b0e90500ec76cdfabf867171ca94045f 111 Pfam PF00936 BMC domain 40 102 1.5E-11 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS00950 b0e90500ec76cdfabf867171ca94045f 111 SUPERFAMILY SSF143414 39 107 8.63E-13 T 28-03-2018 WM46_RS15965 313a852eff3f9b6ac0ccb15d127854e6 295 Pfam PF01738 Dienelactone hydrolase family 85 293 3.8E-53 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 WM46_RS15965 313a852eff3f9b6ac0ccb15d127854e6 295 Gene3D G3DSA:3.40.50.1820 67 293 7.8E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS15965 313a852eff3f9b6ac0ccb15d127854e6 295 SUPERFAMILY SSF53474 69 294 9.24E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS14020 b89964a530ac113019958be235ce5b01 232 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 3.1E-134 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS14020 b89964a530ac113019958be235ce5b01 232 SUPERFAMILY SSF53167 1 229 1.96E-74 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS14020 b89964a530ac113019958be235ce5b01 232 Pfam PF01048 Phosphorylase superfamily 2 226 1.9E-47 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS14020 b89964a530ac113019958be235ce5b01 232 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 229 47.518 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 WM46_RS14020 b89964a530ac113019958be235ce5b01 232 Gene3D G3DSA:3.40.50.1580 1 232 8.7E-57 T 28-03-2018 WM46_RS00325 2006d2aa81e8e77957da3267747c9dd2 232 Pfam PF03942 DTW domain 30 211 5.6E-40 T 28-03-2018 IPR005636 DTW WM46_RS00325 2006d2aa81e8e77957da3267747c9dd2 232 SMART SM01144 27 218 2.7E-68 T 28-03-2018 IPR005636 DTW WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 Gene3D G3DSA:1.10.10.10 1 83 6.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 Pfam PF03466 LysR substrate binding domain 90 287 1.7E-41 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 Gene3D G3DSA:3.40.190.10 175 265 5.6E-22 T 28-03-2018 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 Gene3D G3DSA:3.40.190.10 89 174 4.1E-15 T 28-03-2018 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 SUPERFAMILY SSF53850 90 295 6.29E-41 T 28-03-2018 WM46_RS21735 4d4aa85eb0a7ffa436cd20138d8b87bc 300 SUPERFAMILY SSF46785 1 86 9.85E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 103 128 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 SMART SM00922 147 243 3.4E-11 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 SUPERFAMILY SSF54826 1 129 2.46E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 Gene3D G3DSA:3.30.390.10 1 135 7.7E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 26 128 2.1E-15 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 Pfam PF13378 Enolase C-terminal domain-like 152 359 1.1E-42 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 Gene3D G3DSA:3.20.20.120 136 357 1.6E-41 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS23500 48658ac612b4ee1056a3375fa55306fb 367 SUPERFAMILY SSF51604 116 365 1.03E-48 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 Pfam PF03466 LysR substrate binding domain 95 293 2.3E-23 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.2E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 Gene3D G3DSA:3.40.190.10 186 267 4.5E-13 T 28-03-2018 WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 Gene3D G3DSA:3.40.190.10 93 185 6.8E-15 T 28-03-2018 WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 Gene3D G3DSA:1.10.10.10 2 91 1.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 SUPERFAMILY SSF53850 95 294 3.04E-34 T 28-03-2018 WM46_RS15195 5992259ac99c7514666ba3e0237c799f 305 SUPERFAMILY SSF46785 4 86 2.59E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25175 f9b819ac8d4b9b0899549f4353a5f798 468 SUPERFAMILY SSF103473 27 447 2.75E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS25175 f9b819ac8d4b9b0899549f4353a5f798 468 Gene3D G3DSA:1.20.1250.20 34 231 2.5E-34 T 28-03-2018 WM46_RS25175 f9b819ac8d4b9b0899549f4353a5f798 468 Pfam PF00083 Sugar (and other) transporter 50 448 7.2E-53 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS25175 f9b819ac8d4b9b0899549f4353a5f798 468 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS25175 f9b819ac8d4b9b0899549f4353a5f798 468 Gene3D G3DSA:1.20.1250.20 247 453 4.4E-26 T 28-03-2018 WM46_RS14905 dd038bd1375914a967e47b974e7aa3a6 275 Pfam PF11392 Protein of unknown function (DUF2877) 148 249 2.6E-25 T 28-03-2018 IPR021530 Protein of unknown function DUF2877 WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 2.6E-31 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.2E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 Gene3D G3DSA:3.30.1340.10 1 85 2.8E-32 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 SUPERFAMILY SSF55594 1 82 1.44E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.5E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.5E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS01130 30f33c2d8de065a355696e4e16a20b30 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.5E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS25800 d83aef6be77eb120c4fa93eba74d6461 500 Gene3D G3DSA:3.30.565.10 9 217 6.9E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS25800 d83aef6be77eb120c4fa93eba74d6461 500 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 23 161 1.9E-28 T 28-03-2018 WM46_RS25800 d83aef6be77eb120c4fa93eba74d6461 500 SUPERFAMILY SSF55874 24 227 1.44E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS15960 d96c74e7513e354050f75ce710dc1ca7 865 SUPERFAMILY SSF103515 565 865 2.75E-28 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS15960 d96c74e7513e354050f75ce710dc1ca7 865 Gene3D G3DSA:2.40.128.130 543 865 2.3E-29 T 28-03-2018 WM46_RS15960 d96c74e7513e354050f75ce710dc1ca7 865 Pfam PF03797 Autotransporter beta-domain 591 838 1.5E-27 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS15960 d96c74e7513e354050f75ce710dc1ca7 865 SMART SM00869 588 855 3.0E-27 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 SMART SM00257 404 446 6.0E-13 T 28-03-2018 IPR018392 LysM domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 SMART SM00257 345 388 1.5E-15 T 28-03-2018 IPR018392 LysM domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 SUPERFAMILY SSF53955 102 252 5.06E-41 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 Gene3D G3DSA:1.10.530.10 69 249 4.5E-34 T 28-03-2018 WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 SUPERFAMILY SSF54106 344 387 3.79E-11 T 28-03-2018 IPR018392 LysM domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 SUPERFAMILY SSF54106 403 446 5.36E-11 T 28-03-2018 IPR018392 LysM domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 Pfam PF01464 Transglycosylase SLT domain 105 219 2.8E-29 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 Gene3D G3DSA:3.10.350.10 331 400 9.5E-15 T 28-03-2018 WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 Pfam PF01476 LysM domain 405 445 5.4E-11 T 28-03-2018 IPR018392 LysM domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 Pfam PF01476 LysM domain 346 387 1.5E-13 T 28-03-2018 IPR018392 LysM domain WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 124 152 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 WM46_RS13760 fb2cc54187c238235e1d3655f90731ad 455 Gene3D G3DSA:3.10.350.10 401 448 5.0E-16 T 28-03-2018 WM46_RS11055 3dc0757b81c9d304810943bc7af5bc90 310 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 281 7.1E-92 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B WM46_RS11055 3dc0757b81c9d304810943bc7af5bc90 310 SMART SM00797 23 298 2.7E-144 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B WM46_RS11055 3dc0757b81c9d304810943bc7af5bc90 310 SUPERFAMILY SSF50891 174 288 2.31E-12 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS11055 3dc0757b81c9d304810943bc7af5bc90 310 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 309 8.7E-134 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 8.8E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 SUPERFAMILY SSF46894 124 218 4.25E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 Gene3D G3DSA:1.10.10.10 123 223 2.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 SMART SM00448 1 112 1.1E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 Gene3D G3DSA:3.40.50.2300 1 122 2.6E-36 T 28-03-2018 WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 SMART SM00862 144 217 8.8E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 SUPERFAMILY SSF52172 1 132 1.42E-37 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS25765 ed21abb13e60bd687b49b7594f0a6c5f 224 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS00205 ea06a0c7055f919928a361263e7d5338 138 Pfam PF11162 Protein of unknown function (DUF2946) 16 130 1.2E-16 T 28-03-2018 IPR021333 Protein of unknown function DUF2946 WM46_RS08465 b0e4341fb3b8e9bf4dbc3bd75477ca02 416 SMART SM01329 28 412 1.1E-180 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM46_RS08465 b0e4341fb3b8e9bf4dbc3bd75477ca02 416 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 29 412 1.8E-117 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM46_RS08465 b0e4341fb3b8e9bf4dbc3bd75477ca02 416 Gene3D G3DSA:3.40.718.10 10 416 1.9E-134 T 28-03-2018 WM46_RS08465 b0e4341fb3b8e9bf4dbc3bd75477ca02 416 SUPERFAMILY SSF53659 3 416 2.69E-150 T 28-03-2018 WM46_RS08465 b0e4341fb3b8e9bf4dbc3bd75477ca02 416 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 303 322 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 WM46_RS08465 b0e4341fb3b8e9bf4dbc3bd75477ca02 416 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 1 416 2.4E-239 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 WM46_RS14960 1f513d61e04efbd02ecf43941e7d8348 225 Pfam PF00005 ABC transporter 25 170 1.1E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS14960 1f513d61e04efbd02ecf43941e7d8348 225 Gene3D G3DSA:3.40.50.300 18 223 4.1E-34 T 28-03-2018 WM46_RS14960 1f513d61e04efbd02ecf43941e7d8348 225 SUPERFAMILY SSF52540 21 219 1.05E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14960 1f513d61e04efbd02ecf43941e7d8348 225 SMART SM00382 27 218 2.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07165 0602348e5ce99167a99df131a57278ae 67 Pfam PF14001 YdfZ protein 2 65 1.6E-35 T 28-03-2018 IPR017704 Putative selenium-binding protein YdfZ WM46_RS07165 0602348e5ce99167a99df131a57278ae 67 TIGRFAM TIGR03318 YdfZ_fam: putative selenium-binding protein YdfZ 1 65 9.6E-39 T 28-03-2018 IPR017704 Putative selenium-binding protein YdfZ WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 Pfam PF00083 Sugar (and other) transporter 17 229 4.5E-25 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 Gene3D G3DSA:1.20.1250.20 2 217 1.8E-23 T 28-03-2018 WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 SUPERFAMILY SSF103473 13 428 1.57E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 Pfam PF07690 Major Facilitator Superfamily 255 430 4.6E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 Gene3D G3DSA:1.20.1250.20 235 438 8.8E-22 T 28-03-2018 WM46_RS06345 e49a6c6aa9f8002af691b5f25c3b9d64 439 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 313 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS14865 9ee6bd697316ce6f68dece3e803b27e8 171 Pfam PF01931 Protein of unknown function DUF84 7 165 2.5E-53 T 28-03-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 WM46_RS14865 9ee6bd697316ce6f68dece3e803b27e8 171 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 7 170 2.0E-68 T 28-03-2018 IPR002786 Non-canonical purine NTP phosphatase WM46_RS14865 9ee6bd697316ce6f68dece3e803b27e8 171 Hamap MF_00648 Non-canonical purine NTP phosphatase. 2 171 29.752 T 28-03-2018 IPR002786 Non-canonical purine NTP phosphatase WM46_RS14865 9ee6bd697316ce6f68dece3e803b27e8 171 SUPERFAMILY SSF52972 2 167 1.53E-56 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS14865 9ee6bd697316ce6f68dece3e803b27e8 171 Gene3D G3DSA:3.90.950.10 1 170 2.3E-60 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS08470 6feb1c8b84b0d89510d4dbdba2367fe2 221 Pfam PF00849 RNA pseudouridylate synthase 41 186 9.6E-13 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS08470 6feb1c8b84b0d89510d4dbdba2367fe2 221 SUPERFAMILY SSF55120 37 217 6.56E-43 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS08470 6feb1c8b84b0d89510d4dbdba2367fe2 221 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 76 90 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS08470 6feb1c8b84b0d89510d4dbdba2367fe2 221 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 45 216 2.5E-61 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS08470 6feb1c8b84b0d89510d4dbdba2367fe2 221 Gene3D G3DSA:3.30.70.580 33 119 1.3E-14 T 28-03-2018 WM46_RS08470 6feb1c8b84b0d89510d4dbdba2367fe2 221 Gene3D G3DSA:3.30.70.1560 120 202 1.7E-24 T 28-03-2018 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 Hamap MF_00600 60 kDa chaperonin [groL]. 2 547 41.484 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 SUPERFAMILY SSF48592 406 521 3.51E-77 T 28-03-2018 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 SUPERFAMILY SSF48592 7 134 3.51E-77 T 28-03-2018 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 7.4E-95 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 5.7E-257 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 SUPERFAMILY SSF54849 137 203 1.42E-24 T 28-03-2018 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 SUPERFAMILY SSF52029 185 376 2.27E-83 T 28-03-2018 IPR027409 GroEL-like apical domain WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 Gene3D G3DSA:1.10.560.10 1 184 1.2E-43 T 28-03-2018 IPR027413 GroEL-like equatorial domain WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 Gene3D G3DSA:1.10.560.10 374 516 9.6E-24 T 28-03-2018 IPR027413 GroEL-like equatorial domain WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 Gene3D G3DSA:3.50.7.10 185 373 8.9E-98 T 28-03-2018 IPR027409 GroEL-like apical domain WM46_RS22735 d75fc218ba7e8b7da0b4b69c674dd082 548 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 Gene3D G3DSA:3.30.70.20 1 19 0.021 T 28-03-2018 WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 Gene3D G3DSA:3.30.70.20 55 84 4.3E-10 T 28-03-2018 WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 Gene3D G3DSA:3.30.70.20 85 189 2.0E-16 T 28-03-2018 WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 SUPERFAMILY SSF54862 136 182 1.99E-41 T 28-03-2018 WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 SUPERFAMILY SSF54862 2 101 1.99E-41 T 28-03-2018 WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 Pfam PF13247 4Fe-4S dicluster domain 47 97 1.1E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS25390 e2ea37161a947ca4739cfbfc8c85c212 203 Gene3D G3DSA:3.30.70.20 20 54 7.7E-9 T 28-03-2018 WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 SUPERFAMILY SSF51735 6 255 2.08E-87 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 9.6E-5 T 28-03-2018 WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 254 1.9E-70 T 28-03-2018 WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 Gene3D G3DSA:3.40.50.720 1 252 2.2E-80 T 28-03-2018 WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS01065 65261c5eec2d0dc1784cbcddd86a9fa1 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.5E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18905 05a48f87e28a8cc829c3e08fcc817ec7 194 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 7 187 9.4E-68 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 WM46_RS18905 05a48f87e28a8cc829c3e08fcc817ec7 194 SUPERFAMILY SSF53448 7 187 6.98E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18905 05a48f87e28a8cc829c3e08fcc817ec7 194 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 190 28.843 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 WM46_RS18905 05a48f87e28a8cc829c3e08fcc817ec7 194 Gene3D G3DSA:3.90.550.10 1 193 1.8E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18905 05a48f87e28a8cc829c3e08fcc817ec7 194 Pfam PF12804 MobA-like NTP transferase domain 9 160 7.3E-34 T 28-03-2018 IPR025877 MobA-like NTP transferase WM46_RS23655 81c0d01ab2e0f4ef3a1adde33404ad8e 248 SUPERFAMILY SSF51366 17 240 1.49E-32 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS23655 81c0d01ab2e0f4ef3a1adde33404ad8e 248 Gene3D G3DSA:3.20.20.70 8 244 3.7E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS23655 81c0d01ab2e0f4ef3a1adde33404ad8e 248 Pfam PF00834 Ribulose-phosphate 3 epimerase family 24 227 1.4E-33 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS24450 0e9c6b5b9c42b0077f4b4b4714d22fae 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 278 3.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS24450 0e9c6b5b9c42b0077f4b4b4714d22fae 290 Gene3D G3DSA:1.10.3720.10 57 287 1.3E-43 T 28-03-2018 WM46_RS24450 0e9c6b5b9c42b0077f4b4b4714d22fae 290 Gene3D G3DSA:1.20.58.370 1 36 3.3E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain WM46_RS24450 0e9c6b5b9c42b0077f4b4b4714d22fae 290 SUPERFAMILY SSF161098 50 276 7.72E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS23735 aac557a9d3f164328838ff5f4e0564bc 449 SUPERFAMILY SSF103473 6 436 2.49E-90 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS23735 aac557a9d3f164328838ff5f4e0564bc 449 Gene3D G3DSA:1.20.1250.20 8 209 3.6E-43 T 28-03-2018 WM46_RS23735 aac557a9d3f164328838ff5f4e0564bc 449 Pfam PF07690 Major Facilitator Superfamily 22 379 1.1E-59 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS23735 aac557a9d3f164328838ff5f4e0564bc 449 Gene3D G3DSA:1.20.1250.20 246 445 7.8E-31 T 28-03-2018 WM46_RS23735 aac557a9d3f164328838ff5f4e0564bc 449 PIRSF PIRSF002808 1 448 1.0E-49 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 SMART SM00934 16 237 8.0E-99 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 68 81 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 15 237 1.3E-51 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 17 237 5.3E-54 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 14 242 39.933 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 Gene3D G3DSA:3.20.20.70 11 242 1.1E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS05940 1469e6c8d4f2db5d3b9518cd7aec0c56 245 SUPERFAMILY SSF51366 15 240 8.32E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 397 6.2E-163 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 SUPERFAMILY SSF102645 184 401 2.35E-79 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 Pfam PF02441 Flavoprotein 6 176 2.4E-41 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 187 371 1.1E-72 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 Gene3D G3DSA:3.40.50.1950 1 183 2.2E-52 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 SUPERFAMILY SSF52507 3 179 9.68E-58 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 WM46_RS20135 670d76f42fa76cded0647f55c78b72bf 406 Gene3D G3DSA:3.40.50.10300 184 405 2.6E-67 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 WM46_RS17110 8a09fa7fd5b380ab343431c7ebccd670 310 SUPERFAMILY SSF111369 46 216 1.31E-22 T 28-03-2018 WM46_RS17110 8a09fa7fd5b380ab343431c7ebccd670 310 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 240 2.0E-33 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS17110 8a09fa7fd5b380ab343431c7ebccd670 310 Hamap MF_01544 p-hydroxybenzoic acid efflux pump subunit AaeA [aaeA]. 1 310 60.312 T 28-03-2018 IPR022871 Para-hydroxybenzoic acid efflux pump, subunit AaeA WM46_RS17110 8a09fa7fd5b380ab343431c7ebccd670 310 Gene3D G3DSA:1.20.1600.10 39 287 7.1E-18 T 28-03-2018 WM46_RS17110 8a09fa7fd5b380ab343431c7ebccd670 310 Pfam PF13533 Biotin-lipoyl like 47 95 6.8E-18 T 28-03-2018 WM46_RS17110 8a09fa7fd5b380ab343431c7ebccd670 310 Pfam PF13437 HlyD family secretion protein 156 238 3.0E-9 T 28-03-2018 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 Gene3D G3DSA:3.30.540.10 6 197 5.2E-62 T 28-03-2018 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PIRSF PIRSF000904 1 331 6.4E-121 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 177 200 7.1E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 27 54 7.1E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 146 169 7.1E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 203 230 7.1E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 302 327 7.1E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 64 90 7.1E-71 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 Gene3D G3DSA:3.40.190.80 198 329 2.3E-57 T 28-03-2018 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 2 328 41.966 T 28-03-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 268 280 - T 28-03-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 PIRSF PIRSF500210 1 330 1.6E-124 T 28-03-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 3 192 2.2E-83 T 28-03-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 WM46_RS23170 2cbd0aaaa0c9b9a15057ab9f1b2b3190 332 SUPERFAMILY SSF56655 2 326 6.81E-112 T 28-03-2018 WM46_RS06100 c4bd5935a9efa0b191f020e30fb87b8a 465 Pfam PF04317 YcjX-like family, DUF463 20 464 3.9E-184 T 28-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein WM46_RS06100 c4bd5935a9efa0b191f020e30fb87b8a 465 PIRSF PIRSF019381 1 465 9.7E-217 T 28-03-2018 IPR007413 Protein of unknown function DUF463, YcjX-like protein WM46_RS06100 c4bd5935a9efa0b191f020e30fb87b8a 465 Gene3D G3DSA:3.40.50.300 14 436 2.0E-15 T 28-03-2018 WM46_RS21385 27bfd7278dd4704498dba39ff1ffb6fa 105 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 39 83 2.5E-5 T 28-03-2018 IPR009241 Toxin HigB-like WM46_RS21385 27bfd7278dd4704498dba39ff1ffb6fa 105 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 3 95 1.6E-38 T 28-03-2018 IPR014056 Addiction module killer protein, predicted WM46_RS21385 27bfd7278dd4704498dba39ff1ffb6fa 105 PIRSF PIRSF028744 1 101 3.1E-37 T 28-03-2018 IPR014056 Addiction module killer protein, predicted WM46_RS06465 b4be441fb9eb46f476ab219b9d78da4e 92 Gene3D G3DSA:3.40.50.2300 1 91 1.5E-20 T 28-03-2018 WM46_RS06465 b4be441fb9eb46f476ab219b9d78da4e 92 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 60 6.1E-12 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS06465 b4be441fb9eb46f476ab219b9d78da4e 92 SUPERFAMILY SSF52794 1 89 8.11E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS16715 a25c57f9e73df945a8eb4abc3c2408f1 331 Pfam PF01136 Peptidase family U32 76 330 2.3E-65 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS16715 a25c57f9e73df945a8eb4abc3c2408f1 331 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 WM46_RS16715 a25c57f9e73df945a8eb4abc3c2408f1 331 Gene3D G3DSA:3.20.20.150 9 329 5.0E-18 T 28-03-2018 WM46_RS16715 a25c57f9e73df945a8eb4abc3c2408f1 331 SUPERFAMILY SSF51391 11 162 3.14E-5 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 48 1.0E-15 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 PRINTS PR00045 Sigma-54 factor signature 186 203 2.5E-31 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 PRINTS PR00045 Sigma-54 factor signature 376 388 2.5E-31 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 PRINTS PR00045 Sigma-54 factor signature 450 468 2.5E-31 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 PRINTS PR00045 Sigma-54 factor signature 392 403 2.5E-31 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 Pfam PF04552 Sigma-54, DNA binding domain 317 475 9.9E-71 T 28-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 Pfam PF04963 Sigma-54 factor, core binding domain 114 303 1.1E-61 T 28-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 474 2.4E-164 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 Gene3D G3DSA:1.10.10.10 323 410 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 PIRSF PIRSF000774 1 477 1.3E-153 T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 455 462 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS16935 28ae902ed023a24adbd28b56bd90c41f 477 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 364 383 - T 28-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 WM46_RS13660 82139a46b87b67f7ddfbb35875dce886 133 Hamap MF_01178 Sigma factor-binding protein Crl [crl]. 1 128 32.611 T 28-03-2018 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 WM46_RS13660 82139a46b87b67f7ddfbb35875dce886 133 Pfam PF07417 Transcriptional regulator Crl 5 122 3.7E-54 T 28-03-2018 IPR009986 Sigma factor-binding protein Crl GO:0005737|GO:0045893 WM46_RS19150 9377658c72d306106f4507b04d1c8523 394 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 35 363 1.0E-133 T 28-03-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX WM46_RS19150 9377658c72d306106f4507b04d1c8523 394 Gene3D G3DSA:3.90.20.10 33 138 1.0E-4 T 28-03-2018 WM46_RS09350 081a39a6a43bc78ef953a0b3e918667b 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 194 2.0E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS09350 081a39a6a43bc78ef953a0b3e918667b 304 SUPERFAMILY SSF51735 2 241 6.3E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS09350 081a39a6a43bc78ef953a0b3e918667b 304 SUPERFAMILY SSF51735 275 300 6.3E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS09350 081a39a6a43bc78ef953a0b3e918667b 304 Gene3D G3DSA:3.40.50.720 2 303 1.2E-48 T 28-03-2018 WM46_RS05360 009d99902ff3acbbc756123e643420f2 382 Gene3D G3DSA:3.90.320.10 47 201 1.1E-5 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 WM46_RS05360 009d99902ff3acbbc756123e643420f2 382 Pfam PF12705 PD-(D/E)XK nuclease superfamily 17 268 1.0E-11 T 28-03-2018 WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 Pfam PF12146 Serine aminopeptidase, S33 52 312 5.2E-58 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 SUPERFAMILY SSF53474 35 167 3.92E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 SUPERFAMILY SSF53474 250 329 3.92E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 Gene3D G3DSA:3.40.50.1820 24 338 8.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 3.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 96 3.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 262 276 3.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS19055 4c13dd5fbea86c45b4cff32ef7fd8798 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 3.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS19860 41003bd820543a25d30eaae809da522b 444 Pfam PF00860 Permease family 32 405 6.2E-46 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS19860 41003bd820543a25d30eaae809da522b 444 PIRSF PIRSF005353 6 444 1.0E-170 T 28-03-2018 IPR026033 Purine permease PbuG-like WM46_RS20775 62a2af75a3f72231d173ee3a6c0099f4 680 SUPERFAMILY SSF55486 1 677 4.88E-214 T 28-03-2018 WM46_RS20775 62a2af75a3f72231d173ee3a6c0099f4 680 Pfam PF01432 Peptidase family M3 222 677 8.5E-175 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 WM46_RS20775 62a2af75a3f72231d173ee3a6c0099f4 680 Gene3D G3DSA:1.10.1370.10 457 680 1.9E-69 T 28-03-2018 WM46_RS20775 62a2af75a3f72231d173ee3a6c0099f4 680 Gene3D G3DSA:1.10.1370.10 140 443 9.1E-60 T 28-03-2018 WM46_RS20775 62a2af75a3f72231d173ee3a6c0099f4 680 Gene3D G3DSA:1.20.1050.40 4 138 7.2E-39 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 Gene3D G3DSA:3.40.50.1240 1 213 6.4E-54 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 Hamap MF_01040 Probable phosphoglycerate mutase GpmB [gpmB]. 1 215 61.563 T 28-03-2018 IPR023086 Phosphoglycerate mutase, GpmB, probable GO:0004619|GO:0006096 WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 192 7.8E-57 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 SUPERFAMILY SSF53254 1 208 4.45E-58 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 SMART SM00855 3 157 4.0E-24 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS14860 ed464cab4e081334a56d506a6afca94e 215 PIRSF PIRSF000709 2 171 2.7E-8 T 28-03-2018 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 6 319 4.7E-135 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 265 280 4.2E-54 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 4.2E-54 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 4.2E-54 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 295 314 4.2E-54 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 4.2E-54 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 240 256 4.2E-54 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 Gene3D G3DSA:3.20.20.70 1 321 1.3E-137 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 240 252 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 SUPERFAMILY SSF51569 4 319 5.42E-129 T 28-03-2018 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 PIRSF PIRSF001415 1 323 9.5E-148 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS13055 62718be5cd6cd253aeeb10ec6e8a725f 324 SMART SM01004 3 321 4.6E-207 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 SUPERFAMILY SSF53671 18 372 3.8E-58 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 186 372 2.8E-41 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 177 9.6E-25 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 TIGRFAM TIGR03316 ygeW: knotted carbamoyltransferase YgeW 5 393 1.5E-200 T 28-03-2018 IPR017702 Putative carbamoyltransferase YgeW WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 56 78 2.6E-7 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 180 2.6E-7 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 PRINTS PR00101 Aspartate carbamoyltransferase signature 94 103 2.6E-7 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 322 331 1.0E-8 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 66 85 1.0E-8 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 340 363 1.0E-8 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 Gene3D G3DSA:3.40.50.1370 7 176 3.3E-33 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS24365 c7e50bbef97d2fcc22c87f2d2cf15601 395 Gene3D G3DSA:3.40.50.1370 177 377 6.2E-38 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 SUPERFAMILY SSF54631 200 335 3.87E-22 T 28-03-2018 WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 SMART SM01091 346 426 6.0E-30 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 Pfam PF03471 Transporter associated domain 347 425 1.4E-22 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 Pfam PF01595 Domain of unknown function DUF21 6 197 1.6E-38 T 28-03-2018 IPR002550 Domain of unknown function DUF21 WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 SUPERFAMILY SSF56176 344 428 3.54E-24 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 Pfam PF00571 CBS domain 284 333 0.0026 T 28-03-2018 IPR000644 CBS domain WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 Gene3D G3DSA:3.30.465.10 342 426 2.3E-24 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS23085 c07ecddcb0045f88ace229e5d464657f 445 Gene3D G3DSA:3.10.580.10 191 341 1.8E-21 T 28-03-2018 WM46_RS17415 5570f7f183ec92da3d453fe59dfdc07f 128 SUPERFAMILY SSF64263 1 118 3.53E-51 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17415 5570f7f183ec92da3d453fe59dfdc07f 128 Gene3D G3DSA:3.90.1030.10 1 117 3.2E-50 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17415 5570f7f183ec92da3d453fe59dfdc07f 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.022 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17415 5570f7f183ec92da3d453fe59dfdc07f 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17415 5570f7f183ec92da3d453fe59dfdc07f 128 Pfam PF01196 Ribosomal protein L17 20 116 1.3E-34 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17415 5570f7f183ec92da3d453fe59dfdc07f 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 6.9E-51 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 Gene3D G3DSA:1.10.860.10 18 169 3.5E-48 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 Pfam PF03796 DnaB-like helicase C terminal domain 206 462 4.3E-111 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 SUPERFAMILY SSF52540 204 275 4.5E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 SUPERFAMILY SSF52540 302 456 4.5E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 Gene3D G3DSA:3.40.50.300 187 471 4.4E-64 T 28-03-2018 WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 SUPERFAMILY SSF48024 25 136 6.93E-39 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 Pfam PF00772 DnaB-like helicase N terminal domain 27 128 2.2E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 SMART SM00382 223 429 4.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21635 1138943f76612b54e12a7de9b7b18bb0 471 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 27 464 1.5E-174 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 WM46_RS22495 fc687443e4c2be02c567085b3c3cb64d 286 Pfam PF00486 Transcriptional regulatory protein, C terminal 41 112 9.8E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS22495 fc687443e4c2be02c567085b3c3cb64d 286 SMART SM00862 39 115 1.6E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS22495 fc687443e4c2be02c567085b3c3cb64d 286 Gene3D G3DSA:1.10.10.10 11 119 7.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22495 fc687443e4c2be02c567085b3c3cb64d 286 SUPERFAMILY SSF46894 41 114 1.67E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 SUPERFAMILY SSF47384 236 308 3.53E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 460 1.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 SMART SM00387 354 461 5.4E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 SMART SM00388 246 312 3.2E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 Gene3D G3DSA:1.10.287.130 233 308 8.2E-14 T 28-03-2018 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 Gene3D G3DSA:3.30.450.20 31 161 9.2E-10 T 28-03-2018 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 SUPERFAMILY SSF103190 35 158 1.29E-13 T 28-03-2018 IPR029151 Periplasmic sensor domain-like WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 SUPERFAMILY SSF55874 302 460 5.5E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 308 7.3E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 Gene3D G3DSA:3.30.565.10 312 468 1.7E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 420 5.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 5.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 5.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS21285 84b6469a8270aa3ef0496edb33d94b12 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 406 5.7E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS11760 734cdebd2b9caaa5ca0b48da00a40388 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS11760 734cdebd2b9caaa5ca0b48da00a40388 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS11760 734cdebd2b9caaa5ca0b48da00a40388 193 SUPERFAMILY SSF46689 3 76 8.98E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS11760 734cdebd2b9caaa5ca0b48da00a40388 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site WM46_RS11760 734cdebd2b9caaa5ca0b48da00a40388 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 4.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS11760 734cdebd2b9caaa5ca0b48da00a40388 193 Gene3D G3DSA:1.10.357.10 1 193 4.6E-26 T 28-03-2018 WM46_RS19585 406bcdb9bc9829678d06563f91e13df1 188 Gene3D G3DSA:3.40.50.360 1 188 1.5E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS19585 406bcdb9bc9829678d06563f91e13df1 188 Pfam PF03358 NADPH-dependent FMN reductase 6 148 5.7E-39 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 WM46_RS19585 406bcdb9bc9829678d06563f91e13df1 188 SUPERFAMILY SSF52218 6 178 2.48E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 PIRSF PIRSF002808 5 452 3.3E-176 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 Gene3D G3DSA:1.20.1250.20 18 224 1.9E-34 T 28-03-2018 WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 440 5.3E-269 T 28-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 SUPERFAMILY SSF103473 13 442 5.23E-84 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 417 3.5E-168 T 28-03-2018 WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 Pfam PF07690 Major Facilitator Superfamily 34 400 7.4E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 28-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 WM46_RS01975 b50e959b38db038c58aae5452f6a8799 452 Gene3D G3DSA:1.20.1250.20 240 451 2.0E-31 T 28-03-2018 WM46_RS14365 8a81ea4f3515a99ea4e1bc040bfdd506 276 Pfam PF03799 Cell division protein FtsQ 130 247 2.2E-27 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB WM46_RS14365 8a81ea4f3515a99ea4e1bc040bfdd506 276 Pfam PF08478 POTRA domain, FtsQ-type 57 126 2.1E-20 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type WM46_RS14365 8a81ea4f3515a99ea4e1bc040bfdd506 276 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 26 255 25.955 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 WM46_RS01465 465b6a2d8a5ea706d126e8891b74394c 446 SUPERFAMILY SSF56935 26 446 3.53E-116 T 28-03-2018 WM46_RS01465 465b6a2d8a5ea706d126e8891b74394c 446 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 17 446 5.4E-154 T 28-03-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) WM46_RS01465 465b6a2d8a5ea706d126e8891b74394c 446 Gene3D G3DSA:2.40.160.60 26 446 7.4E-87 T 28-03-2018 WM46_RS11305 ea18c78a15b3a987ade66e05e78f44d5 155 SUPERFAMILY SSF55486 3 151 1.34E-50 T 28-03-2018 WM46_RS11305 ea18c78a15b3a987ade66e05e78f44d5 155 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 144 1.6E-36 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 WM46_RS11305 ea18c78a15b3a987ade66e05e78f44d5 155 Pfam PF02130 Uncharacterized protein family UPF0054 20 142 1.2E-38 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 WM46_RS11305 ea18c78a15b3a987ade66e05e78f44d5 155 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 148 24.566 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 WM46_RS11305 ea18c78a15b3a987ade66e05e78f44d5 155 Gene3D G3DSA:3.40.390.30 1 155 4.1E-55 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 WM46_RS11305 ea18c78a15b3a987ade66e05e78f44d5 155 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 114 124 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site WM46_RS17230 df496f24c761d86510d0e7a264a3a33d 80 Pfam PF06196 Protein of unknown function (DUF997) 7 77 9.9E-31 T 28-03-2018 IPR010398 Protein of unknown function DUF997 WM46_RS17230 df496f24c761d86510d0e7a264a3a33d 80 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 1 80 2.0E-29 T 28-03-2018 IPR010398 Protein of unknown function DUF997 WM46_RS20710 3984f1980849e1b0f3c90b8e12111b51 686 Pfam PF05170 AsmA family 1 582 6.0E-176 T 28-03-2018 IPR007844 AsmA WM46_RS20805 2d4375170eb6e8cf068845ade7ddcafc 111 Hamap MF_01088 Universal stress protein B [uspB]. 1 107 39.727 T 28-03-2018 IPR019598 Universal stress protein B WM46_RS20805 2d4375170eb6e8cf068845ade7ddcafc 111 Pfam PF10625 Universal stress protein B (UspB) 1 107 2.3E-54 T 28-03-2018 IPR019598 Universal stress protein B WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 Gene3D G3DSA:1.10.10.10 1 81 4.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 Pfam PF03466 LysR substrate binding domain 86 282 2.8E-35 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 SUPERFAMILY SSF46785 1 84 1.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 Gene3D G3DSA:3.40.190.10 179 261 6.5E-15 T 28-03-2018 WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 SUPERFAMILY SSF53850 87 295 2.02E-35 T 28-03-2018 WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 Gene3D G3DSA:3.40.190.10 86 178 2.3E-17 T 28-03-2018 WM46_RS11175 89915d0bc08dc251c664b1ec47dac8e4 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.7E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS06720 4e217ad8c755e197f6a2869012706a8d 297 SUPERFAMILY SSF54506 1 294 8.13E-68 T 28-03-2018 WM46_RS06720 4e217ad8c755e197f6a2869012706a8d 297 Gene3D G3DSA:3.10.310.10 2 126 1.2E-28 T 28-03-2018 WM46_RS06720 4e217ad8c755e197f6a2869012706a8d 297 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 295 1.4E-119 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM46_RS06720 4e217ad8c755e197f6a2869012706a8d 297 Gene3D G3DSA:3.10.310.10 127 284 5.9E-33 T 28-03-2018 WM46_RS06720 4e217ad8c755e197f6a2869012706a8d 297 Pfam PF02567 Phenazine biosynthesis-like protein 8 290 2.2E-86 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM46_RS06720 4e217ad8c755e197f6a2869012706a8d 297 PIRSF PIRSF016184 1 295 8.5E-93 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM46_RS08820 438723e85f6072843e01d3c4e69ea68d 307 Gene3D G3DSA:3.30.360.10 130 307 1.2E-19 T 28-03-2018 WM46_RS08820 438723e85f6072843e01d3c4e69ea68d 307 SUPERFAMILY SSF51735 3 137 9.67E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08820 438723e85f6072843e01d3c4e69ea68d 307 SUPERFAMILY SSF55347 126 265 3.92E-45 T 28-03-2018 WM46_RS08820 438723e85f6072843e01d3c4e69ea68d 307 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 5.3E-26 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS08820 438723e85f6072843e01d3c4e69ea68d 307 Gene3D G3DSA:3.40.50.720 1 129 1.3E-33 T 28-03-2018 WM46_RS10215 ac26a1fc34b520d1ae9cff81452fd1a0 402 SUPERFAMILY SSF103473 11 390 4.19E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS10215 ac26a1fc34b520d1ae9cff81452fd1a0 402 Gene3D G3DSA:1.20.1250.20 205 394 4.2E-26 T 28-03-2018 WM46_RS10215 ac26a1fc34b520d1ae9cff81452fd1a0 402 Pfam PF07690 Major Facilitator Superfamily 223 396 3.5E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS10215 ac26a1fc34b520d1ae9cff81452fd1a0 402 Gene3D G3DSA:1.20.1250.20 9 204 2.9E-14 T 28-03-2018 WM46_RS19960 824cd90123888bb00a833ce62885a531 247 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 7 244 1.2E-102 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS19960 824cd90123888bb00a833ce62885a531 247 Pfam PF07071 KDGP aldolase 7 226 2.0E-92 T 28-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS19960 824cd90123888bb00a833ce62885a531 247 Gene3D G3DSA:3.20.20.70 3 247 8.6E-103 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS03975 b099760f60ddd4a2478c3844e886dab9 251 Pfam PF01863 Protein of unknown function DUF45 35 241 3.5E-57 T 28-03-2018 IPR002725 Protein of unknown function DUF45 WM46_RS09720 19deaef6d449fb182a1a7d213ffc7d0b 324 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 34 315 5.3E-83 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 WM46_RS09720 19deaef6d449fb182a1a7d213ffc7d0b 324 Pfam PF09084 NMT1/THI5 like 69 187 2.5E-11 T 28-03-2018 IPR015168 SsuA/THI5-like WM46_RS09720 19deaef6d449fb182a1a7d213ffc7d0b 324 SMART SM00062 33 254 1.7E-31 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS09720 19deaef6d449fb182a1a7d213ffc7d0b 324 Gene3D G3DSA:3.40.190.10 29 133 2.0E-16 T 28-03-2018 WM46_RS09720 19deaef6d449fb182a1a7d213ffc7d0b 324 Gene3D G3DSA:3.40.190.10 134 321 9.0E-34 T 28-03-2018 WM46_RS09720 19deaef6d449fb182a1a7d213ffc7d0b 324 SUPERFAMILY SSF53850 31 263 1.85E-49 T 28-03-2018 WM46_RS10220 5fb6fc2850c0a821edfc3aef299c98b2 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 259 1.5E-53 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10220 5fb6fc2850c0a821edfc3aef299c98b2 270 Gene3D G3DSA:3.40.50.1000 1 268 4.0E-34 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10220 5fb6fc2850c0a821edfc3aef299c98b2 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 232 1.9E-18 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 WM46_RS10220 5fb6fc2850c0a821edfc3aef299c98b2 270 SUPERFAMILY SSF56784 1 263 1.32E-61 T 28-03-2018 IPR023214 HAD-like domain WM46_RS10220 5fb6fc2850c0a821edfc3aef299c98b2 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 213 235 - T 28-03-2018 WM46_RS10220 5fb6fc2850c0a821edfc3aef299c98b2 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 8.2E-57 T 28-03-2018 IPR000150 Cof family GO:0016787 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 SUPERFAMILY SSF46894 96 161 2.07E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 104 118 7.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 118 134 7.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 134 146 7.8E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 Pfam PF00196 Bacterial regulatory proteins, luxR family 103 156 4.8E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 SMART SM00421 101 158 5.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS24515 78a8e53163d5f6deebb1ac997ac7d1f6 174 Gene3D G3DSA:1.10.10.10 28 166 2.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 Pfam PF09500 Putative thioesterase (yiiD_Cterm) 174 313 2.6E-48 T 28-03-2018 IPR012660 Thioesterase, putative WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 SUPERFAMILY SSF54637 171 313 2.4E-39 T 28-03-2018 IPR029069 HotDog domain WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 Gene3D G3DSA:3.40.630.30 15 161 2.1E-23 T 28-03-2018 WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 SUPERFAMILY SSF55729 15 162 5.66E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 TIGRFAM TIGR02447 yiiD_Cterm: putative thioesterase domain 181 314 3.9E-47 T 28-03-2018 IPR012660 Thioesterase, putative WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 Pfam PF00583 Acetyltransferase (GNAT) family 43 138 1.2E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS18745 748177afe72d02de9334bff5ed1eb71c 329 Gene3D G3DSA:3.10.129.10 162 316 1.4E-18 T 28-03-2018 WM46_RS05000 7b19cc19bea6cc93a8e0ec0c566960fb 114 Gene3D G3DSA:3.30.1330.40 2 114 6.5E-21 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like WM46_RS05000 7b19cc19bea6cc93a8e0ec0c566960fb 114 SUPERFAMILY SSF55298 5 114 1.18E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like WM46_RS05000 7b19cc19bea6cc93a8e0ec0c566960fb 114 Pfam PF01042 Endoribonuclease L-PSP 5 114 2.6E-27 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family WM46_RS05000 7b19cc19bea6cc93a8e0ec0c566960fb 114 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 90 108 - T 28-03-2018 IPR019897 RidA, conserved site WM46_RS21565 93a5ad262f74904fd2881bf85ab14c53 441 Hamap MF_01301 Maltoporin [lamB]. 4 441 43.3 T 28-03-2018 IPR023738 Maltoporin GO:0009279|GO:0015481|GO:0015768|GO:0042956|GO:0042958 WM46_RS21565 93a5ad262f74904fd2881bf85ab14c53 441 Pfam PF02264 LamB porin 28 441 2.8E-147 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS21565 93a5ad262f74904fd2881bf85ab14c53 441 SUPERFAMILY SSF56935 26 441 5.98E-149 T 28-03-2018 WM46_RS21565 93a5ad262f74904fd2881bf85ab14c53 441 Gene3D G3DSA:2.40.170.10 26 441 2.8E-162 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS21565 93a5ad262f74904fd2881bf85ab14c53 441 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 32 437 0.0 T 28-03-2018 IPR003192 Porin, LamB type GO:0006810|GO:0016020 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 Gene3D G3DSA:4.10.430.10 77 116 7.7E-17 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 Gene3D G3DSA:4.10.430.10 29 66 6.1E-13 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 SUPERFAMILY SSF81273 74 116 1.06E-11 T 28-03-2018 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 SMART SM00528 22 67 7.5E-9 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 SMART SM00528 71 116 1.6E-22 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 Pfam PF00816 H-NS histone family 58 108 1.9E-13 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 Pfam PF00816 H-NS histone family 19 59 6.2E-10 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS25965 73c9bd77500f2702c141b0b72e6292ff 116 SUPERFAMILY SSF81273 25 66 1.02E-9 T 28-03-2018 WM46_RS03535 7330fe3210373673e19723725a347df2 269 Pfam PF00230 Major intrinsic protein 6 249 1.8E-64 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 PRINTS PR00783 Major intrinsic protein family signature 182 204 2.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 PRINTS PR00783 Major intrinsic protein family signature 149 167 2.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 PRINTS PR00783 Major intrinsic protein family signature 232 252 2.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 PRINTS PR00783 Major intrinsic protein family signature 46 70 2.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 PRINTS PR00783 Major intrinsic protein family signature 83 102 2.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 PRINTS PR00783 Major intrinsic protein family signature 7 26 2.8E-52 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 249 5.2E-66 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 ProSitePatterns PS00221 MIP family signature. 64 72 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 SUPERFAMILY SSF81338 6 254 2.49E-76 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS03535 7330fe3210373673e19723725a347df2 269 Gene3D G3DSA:1.20.1080.10 1 257 1.6E-74 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS02850 a72e6a8fc75a3ac55a7c5b74f7435484 159 Gene3D G3DSA:3.90.79.10 1 159 7.7E-25 T 28-03-2018 WM46_RS02850 a72e6a8fc75a3ac55a7c5b74f7435484 159 Hamap MF_00941 GDP-mannose mannosyl hydrolase [gmm]. 1 159 50.538 T 28-03-2018 IPR028613 GDP-mannose mannosyl hydrolase, Enterobacteria GO:0000287|GO:0008727|GO:0030145 WM46_RS02850 a72e6a8fc75a3ac55a7c5b74f7435484 159 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS02850 a72e6a8fc75a3ac55a7c5b74f7435484 159 Pfam PF00293 NUDIX domain 18 145 5.7E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS02850 a72e6a8fc75a3ac55a7c5b74f7435484 159 PIRSF PIRSF037599 1 152 5.4E-74 T 28-03-2018 IPR033715 GDP-mannose mannosyl hydrolase GO:0008727 WM46_RS02850 a72e6a8fc75a3ac55a7c5b74f7435484 159 SUPERFAMILY SSF55811 2 147 2.71E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS06545 9470931b3bdec989ec0b38e0a3e9428b 144 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 9 71 6.0E-7 T 28-03-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system WM46_RS06545 9470931b3bdec989ec0b38e0a3e9428b 144 Gene3D G3DSA:1.10.260.40 83 143 1.0E-4 T 28-03-2018 WM46_RS06545 9470931b3bdec989ec0b38e0a3e9428b 144 Gene3D G3DSA:3.30.2390.10 7 78 1.7E-11 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like WM46_RS06545 9470931b3bdec989ec0b38e0a3e9428b 144 SUPERFAMILY SSF47413 88 143 7.64E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS06545 9470931b3bdec989ec0b38e0a3e9428b 144 SUPERFAMILY SSF143100 6 70 5.62E-14 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like WM46_RS22125 02f4eadcadfb0c24cc172a1cd2dfc54c 268 Gene3D G3DSA:3.10.129.10 2 168 9.0E-11 T 28-03-2018 WM46_RS22125 02f4eadcadfb0c24cc172a1cd2dfc54c 268 SUPERFAMILY SSF54637 5 83 2.24E-10 T 28-03-2018 IPR029069 HotDog domain WM46_RS22125 02f4eadcadfb0c24cc172a1cd2dfc54c 268 Pfam PF01575 MaoC like domain 6 44 4.8E-5 T 28-03-2018 IPR002539 MaoC-like domain WM46_RS13225 e6ef82827c125a79790e9095f4fec6ae 135 Gene3D G3DSA:2.60.120.10 14 135 1.7E-29 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS13225 e6ef82827c125a79790e9095f4fec6ae 135 SUPERFAMILY SSF51182 13 133 1.48E-28 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 Pfam PF00005 ABC transporter 346 489 2.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 Pfam PF00005 ABC transporter 26 165 2.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 SMART SM00382 354 535 8.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 SMART SM00382 32 266 8.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 Gene3D G3DSA:3.40.50.300 326 563 1.0E-59 T 28-03-2018 WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 Gene3D G3DSA:3.40.50.300 2 286 7.3E-53 T 28-03-2018 WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 SUPERFAMILY SSF52540 324 549 9.35E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10500 1e3b7523d22ed65f0361c1df2aa0649d 578 SUPERFAMILY SSF52540 5 228 1.71E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10125 589e4c533af4ed8e5d22baac3a6a8f97 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 5 110 1.3E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS10125 589e4c533af4ed8e5d22baac3a6a8f97 222 SUPERFAMILY SSF161098 6 200 3.01E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10125 589e4c533af4ed8e5d22baac3a6a8f97 222 Gene3D G3DSA:1.10.3720.10 1 221 4.5E-28 T 28-03-2018 WM46_RS10125 589e4c533af4ed8e5d22baac3a6a8f97 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 7.8E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS00125 7f351eeb62275f0f570fb3ceca55c40d 468 SUPERFAMILY SSF56954 7 450 1.96E-64 T 28-03-2018 WM46_RS00125 7f351eeb62275f0f570fb3ceca55c40d 468 Gene3D G3DSA:1.20.1600.10 16 453 4.5E-53 T 28-03-2018 WM46_RS00125 7f351eeb62275f0f570fb3ceca55c40d 468 Pfam PF02321 Outer membrane efflux protein 272 445 9.3E-19 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS00125 7f351eeb62275f0f570fb3ceca55c40d 468 Pfam PF02321 Outer membrane efflux protein 61 242 1.0E-25 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS00125 7f351eeb62275f0f570fb3ceca55c40d 468 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 58 463 3.9E-110 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 SUPERFAMILY SSF53067 9 152 8.89E-38 T 28-03-2018 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 SUPERFAMILY SSF53067 153 340 3.69E-50 T 28-03-2018 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Pfam PF06723 MreB/Mbl protein 11 338 1.5E-150 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.30.420.40 8 172 4.3E-42 T 28-03-2018 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 1.2E-65 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 1.2E-65 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 1.2E-65 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 1.2E-65 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 1.2E-65 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.30.420.40 256 321 1.8E-8 T 28-03-2018 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 Gene3D G3DSA:3.90.640.10 190 255 8.8E-28 T 28-03-2018 WM46_RS17170 73d2ba4e5d849d4bc6ef9989dcc9beba 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 9.6E-171 T 28-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 76 3.0E-35 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 1.8E-38 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 Gene3D G3DSA:2.40.50.140 5 82 6.6E-35 T 28-03-2018 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 SUPERFAMILY SSF50249 5 82 1.46E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 5 80 25.191 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 6.5E-14 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 6.5E-14 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 6.5E-14 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17500 90b338e40eebc0f211209d041bcd8c96 84 Pfam PF00366 Ribosomal protein S17 10 76 2.6E-34 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 Pfam PF01872 RibD C-terminal domain 147 362 6.2E-61 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 SUPERFAMILY SSF53927 3 145 1.66E-49 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 SUPERFAMILY SSF53597 144 362 4.83E-59 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 Gene3D G3DSA:3.40.430.10 125 365 3.2E-70 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 Gene3D G3DSA:3.40.140.10 1 124 7.5E-34 T 28-03-2018 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 365 7.5E-81 T 28-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 99 5.2E-23 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 362 8.4E-154 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 WM46_RS12775 57d27d291d78114f5516d0999d27a20b 367 PIRSF PIRSF006769 1 367 1.4E-138 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 TIGRFAM TIGR03152 cyto_c552_HCOOH: formate-dependent cytochrome c nitrite reductase, c552 subunit 38 475 7.1E-250 T 28-03-2018 IPR017570 Formate-dependent cytochrome c nitrite reductase, c552 subunit GO:0005509|GO:0006807|GO:0020037|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 Hamap MF_01182 Cytochrome c-552 [nrfA]. 1 477 59.144 T 28-03-2018 IPR017570 Formate-dependent cytochrome c nitrite reductase, c552 subunit GO:0005509|GO:0006807|GO:0020037|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 PIRSF PIRSF000243 23 478 2.3E-125 T 28-03-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 Gene3D G3DSA:1.20.140.10 304 444 5.9E-44 T 28-03-2018 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 Pfam PF02335 Cytochrome c552 43 472 1.5E-176 T 28-03-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 Gene3D G3DSA:3.90.10.10 78 215 8.7E-8 T 28-03-2018 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 Gene3D G3DSA:1.10.468.10 216 303 2.8E-24 T 28-03-2018 WM46_RS21770 e2ca77b1cab41273b770f8eaec5fa631 478 SUPERFAMILY SSF48695 38 472 3.93E-163 T 28-03-2018 IPR011031 Multihaem cytochrome WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 PIRSF PIRSF006443 1 166 3.1E-61 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 Gene3D G3DSA:3.40.980.10 3 170 2.4E-35 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 153 2.2E-37 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 7 169 3.2E-82 T 28-03-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 SMART SM00852 14 158 5.6E-28 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 SUPERFAMILY SSF53218 8 168 2.49E-45 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10555 466ea0ee274b8ef5cfaf9d98dd90a048 170 Pfam PF00994 Probable molybdopterin binding domain 14 156 7.9E-33 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS00515 3f999969eb221a9b2c2613688823a3df 140 Pfam PF07681 DoxX 16 97 1.3E-18 T 28-03-2018 IPR032808 DoxX family WM46_RS11630 ede104ebd5651ca9aa451cbe29858539 72 SUPERFAMILY SSF160582 3 64 4.58E-23 T 28-03-2018 WM46_RS11630 ede104ebd5651ca9aa451cbe29858539 72 SMART SM00923 5 55 2.3E-21 T 28-03-2018 IPR005153 MbtH-like protein WM46_RS11630 ede104ebd5651ca9aa451cbe29858539 72 Pfam PF03621 MbtH-like protein 4 53 9.2E-21 T 28-03-2018 IPR005153 MbtH-like protein WM46_RS11630 ede104ebd5651ca9aa451cbe29858539 72 Gene3D G3DSA:3.90.820.10 4 63 4.9E-24 T 28-03-2018 WM46_RS17505 b62c1dc417c418f6555850ca214a3656 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 28-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17505 b62c1dc417c418f6555850ca214a3656 63 Pfam PF00831 Ribosomal L29 protein 4 60 1.1E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17505 b62c1dc417c418f6555850ca214a3656 63 SUPERFAMILY SSF46561 1 61 1.2E-21 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17505 b62c1dc417c418f6555850ca214a3656 63 Gene3D G3DSA:1.10.287.310 1 63 1.1E-22 T 28-03-2018 WM46_RS17505 b62c1dc417c418f6555850ca214a3656 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 7.4E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17505 b62c1dc417c418f6555850ca214a3656 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.547 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS03270 374f6ccb1db4f80fb0f592679a8cd1be 83 Pfam PF02831 gpW 15 82 2.9E-24 T 28-03-2018 IPR004174 Head-to-tail joining protein W GO:0019058 WM46_RS03270 374f6ccb1db4f80fb0f592679a8cd1be 83 SUPERFAMILY SSF64210 15 75 7.45E-12 T 28-03-2018 IPR004174 Head-to-tail joining protein W GO:0019058 WM46_RS03270 374f6ccb1db4f80fb0f592679a8cd1be 83 Gene3D G3DSA:3.30.1580.10 16 80 5.2E-22 T 28-03-2018 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 109 551 2.0E-198 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 350 364 - T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Gene3D G3DSA:3.40.50.220 3 107 5.8E-37 T 28-03-2018 IPR027464 Ornithine decarboxylase, N-terminal domain KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Gene3D G3DSA:3.40.640.10 109 419 2.2E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 SUPERFAMILY SSF53383 109 566 1.48E-119 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 SUPERFAMILY SSF55904 571 718 1.44E-46 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 TIGRFAM TIGR04301 ODC_inducible: ornithine decarboxylase SpeF 1 718 0.0 T 28-03-2018 IPR027568 Ornithine decarboxylase SpeF GO:0004586 KEGG: 00330+4.1.1.17|KEGG: 00480+4.1.1.17|MetaCyc: PWY-46|MetaCyc: PWY-6305 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 576 704 3.3E-48 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 4 103 3.6E-25 T 28-03-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 PIRSF PIRSF009393 1 719 1.8E-288 T 28-03-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 SUPERFAMILY SSF52172 1 107 1.39E-35 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Gene3D G3DSA:3.90.1150.10 421 600 2.7E-51 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS11125 93d95031a47d361ed496533dc2543a37 732 Gene3D G3DSA:3.90.100.10 601 727 1.9E-38 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 Gene3D G3DSA:1.10.10.10 11 99 2.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 SUPERFAMILY SSF46785 13 86 1.67E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 Pfam PF01614 Bacterial transcriptional regulator 129 254 3.9E-45 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 SUPERFAMILY SSF55781 77 258 7.19E-55 T 28-03-2018 IPR029016 GAF domain-like WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 Pfam PF09339 IclR helix-turn-helix domain 15 65 2.2E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 Gene3D G3DSA:3.30.450.40 100 263 4.1E-53 T 28-03-2018 IPR029016 GAF domain-like WM46_RS04895 fb58e080f4e90f9d34228122f79b3594 263 SMART SM00346 13 102 9.5E-37 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82693 563 669 2.25E-22 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Pfam PF00873 AcrB/AcrD/AcrF family 3 1023 0.0 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Gene3D G3DSA:3.30.2090.10 181 274 9.4E-17 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82693 39 132 6.28E-27 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Gene3D G3DSA:1.20.1640.10 809 1025 4.6E-35 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Gene3D G3DSA:1.20.1640.10 275 500 4.0E-43 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 2 1026 0.0 T 28-03-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 1.6E-100 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Gene3D G3DSA:3.30.70.1430 565 666 8.1E-15 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82714 721 806 6.67E-16 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Gene3D G3DSA:3.30.70.1440 670 766 1.9E-15 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82866 803 1023 5.62E-40 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82714 183 273 9.16E-22 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82693 275 331 1.88E-21 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82693 137 183 1.88E-21 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 Gene3D G3DSA:3.30.70.1430 39 141 2.6E-28 T 28-03-2018 WM46_RS10365 0a7eca53d73421e6529527f178e30f55 1031 SUPERFAMILY SSF82866 297 498 5.89E-46 T 28-03-2018 WM46_RS09435 3f5353061e1259c3962da134b141319c 157 SUPERFAMILY SSF55804 6 153 1.23E-39 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS09435 3f5353061e1259c3962da134b141319c 157 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 10 138 3.2E-38 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 WM46_RS09435 3f5353061e1259c3962da134b141319c 157 Gene3D G3DSA:3.40.930.10 5 155 4.9E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS09435 3f5353061e1259c3962da134b141319c 157 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 10 152 1.5E-40 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS15625 aa957e7a6117a6def3acd336f901a6e0 502 Pfam PF07916 TraG-like protein, N-terminal region 8 479 2.7E-101 T 28-03-2018 IPR012931 TraG-like, N-terminal WM46_RS22065 4c31773dda7c5fc999f96be1a04de758 207 Pfam PF00419 Fimbrial protein 44 206 5.4E-12 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22065 4c31773dda7c5fc999f96be1a04de758 207 Gene3D G3DSA:2.60.40.1090 41 207 1.8E-27 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22065 4c31773dda7c5fc999f96be1a04de758 207 SUPERFAMILY SSF49401 42 206 3.13E-29 T 28-03-2018 IPR008966 Adhesion domain WM46_RS11485 13b6bc19ffcde0775c8a156278126490 302 SUPERFAMILY SSF51621 11 244 8.72E-62 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS11485 13b6bc19ffcde0775c8a156278126490 302 TIGRFAM TIGR01588 citE: citrate (pro-3S)-lyase, beta subunit 12 299 7.4E-135 T 28-03-2018 IPR006475 Citrate lyase, beta subunit, bacteria GO:0005737|GO:0006084|GO:0008816|GO:0009346 KEGG: 00720+4.1.3.34|MetaCyc: PWY-5392|MetaCyc: PWY-6038 WM46_RS11485 13b6bc19ffcde0775c8a156278126490 302 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 15 234 2.3E-83 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 WM46_RS11485 13b6bc19ffcde0775c8a156278126490 302 Gene3D G3DSA:3.20.20.360 2 273 1.5E-52 T 28-03-2018 WM46_RS11485 13b6bc19ffcde0775c8a156278126490 302 PIRSF PIRSF015582 1 302 1.4E-75 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like WM46_RS10095 0e73250f72c21cb94a81aecdd06a7164 276 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 42 179 3.1E-25 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS10095 0e73250f72c21cb94a81aecdd06a7164 276 Gene3D G3DSA:3.40.80.10 42 192 8.1E-42 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS10095 0e73250f72c21cb94a81aecdd06a7164 276 SUPERFAMILY SSF47090 198 273 2.2E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS10095 0e73250f72c21cb94a81aecdd06a7164 276 Gene3D G3DSA:1.10.101.10 193 276 5.3E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS10095 0e73250f72c21cb94a81aecdd06a7164 276 SUPERFAMILY SSF55846 24 194 1.44E-51 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS10095 0e73250f72c21cb94a81aecdd06a7164 276 SMART SM00644 32 178 1.3E-37 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS26015 eeb90e5c28010d0f88cc1929fbfd10aa 232 SUPERFAMILY SSF54427 93 230 1.88E-39 T 28-03-2018 IPR032710 NTF2-like domain WM46_RS26015 eeb90e5c28010d0f88cc1929fbfd10aa 232 Pfam PF04335 VirB8 protein 26 230 2.7E-38 T 28-03-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 WM46_RS26015 eeb90e5c28010d0f88cc1929fbfd10aa 232 PIRSF PIRSF003299 7 232 2.2E-46 T 28-03-2018 IPR026264 Type IV secretion system protein VirB8/PtlE GO:0030255 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 SUPERFAMILY SSF54719 95 204 7.2E-45 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 PIRSF PIRSF000349 1 206 2.8E-80 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 SUPERFAMILY SSF46609 1 90 4.58E-37 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 89 1.4E-33 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 Gene3D G3DSA:1.10.287.990 20 90 5.8E-31 T 28-03-2018 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 201 3.0E-40 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 168 175 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.7E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 2.7E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.7E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 2.7E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS18545 f633851239995b46f41e4c8e5cc7a832 206 PRINTS PR01703 Manganese superoxide dismutase signature 166 178 2.7E-27 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 WM46_RS25650 2eae12ae80d0d057616deedc55e12fe8 136 Pfam PF07972 NrdI Flavodoxin like 5 122 1.2E-46 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI WM46_RS25650 2eae12ae80d0d057616deedc55e12fe8 136 SUPERFAMILY SSF52218 1 131 2.26E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25650 2eae12ae80d0d057616deedc55e12fe8 136 Gene3D G3DSA:3.40.50.360 4 131 1.3E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS25650 2eae12ae80d0d057616deedc55e12fe8 136 TIGRFAM TIGR00333 nrdI: nrdI protein 5 131 7.6E-58 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI WM46_RS25650 2eae12ae80d0d057616deedc55e12fe8 136 Hamap MF_00128 Protein NrdI [nrdI]. 3 132 36.217 T 28-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial WM46_RS25650 2eae12ae80d0d057616deedc55e12fe8 136 PIRSF PIRSF005087 1 136 5.7E-53 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 Hamap MF_00384 Homoserine kinase [thrB]. 2 307 31.042 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 Pfam PF08544 GHMP kinases C terminal 214 281 2.5E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 PIRSF PIRSF000676 1 308 3.6E-85 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 Gene3D G3DSA:3.30.70.890 168 309 3.3E-29 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 SUPERFAMILY SSF55060 172 289 3.24E-33 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 PRINTS PR00958 Homoserine kinase signature 175 192 2.9E-34 T 28-03-2018 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 PRINTS PR00958 Homoserine kinase signature 9 24 2.9E-34 T 28-03-2018 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 PRINTS PR00958 Homoserine kinase signature 254 269 2.9E-34 T 28-03-2018 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 PRINTS PR00958 Homoserine kinase signature 97 112 2.9E-34 T 28-03-2018 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 PRINTS PR00958 Homoserine kinase signature 137 150 2.9E-34 T 28-03-2018 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 SUPERFAMILY SSF54211 1 160 9.11E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 Gene3D G3DSA:3.30.230.10 1 165 2.4E-27 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 Pfam PF00288 GHMP kinases N terminal domain 85 150 1.5E-13 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 TIGRFAM TIGR00191 thrB: homoserine kinase 2 308 1.6E-120 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 WM46_RS14805 838b804251f86b35a10a645a93c31f82 309 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 90 101 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 WM46_RS16680 690c50b27d159cbca269c74b2207072e 345 Pfam PF03773 Predicted permease 74 341 1.1E-25 T 28-03-2018 IPR005524 Predicted permease DUF318 WM46_RS16680 690c50b27d159cbca269c74b2207072e 345 Pfam PF03773 Predicted permease 57 151 1.0E-11 T 28-03-2018 IPR005524 Predicted permease DUF318 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 Gene3D G3DSA:3.40.630.10 1 280 3.5E-63 T 28-03-2018 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 3 375 52.458 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 97 136 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 SUPERFAMILY SSF55031 179 286 1.64E-29 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 Gene3D G3DSA:3.40.630.10 291 375 2.0E-4 T 28-03-2018 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 SUPERFAMILY SSF53187 292 373 6.55E-66 T 28-03-2018 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 SUPERFAMILY SSF53187 5 178 6.55E-66 T 28-03-2018 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 6 373 1.2E-175 T 28-03-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 Pfam PF01546 Peptidase family M20/M25/M40 62 371 6.7E-45 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 WM46_RS00885 c856192e818028d5f1a7b4157113788a 375 Pfam PF07687 Peptidase dimerisation domain 175 282 1.9E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS15660 106c4d81d191b0c1d0c5b037fcfe75c4 178 Gene3D G3DSA:2.40.50.140 1 120 1.9E-46 T 28-03-2018 WM46_RS15660 106c4d81d191b0c1d0c5b037fcfe75c4 178 Pfam PF00436 Single-strand binding protein family 6 112 1.6E-42 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 WM46_RS15660 106c4d81d191b0c1d0c5b037fcfe75c4 178 SUPERFAMILY SSF50249 4 163 1.58E-60 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS15660 106c4d81d191b0c1d0c5b037fcfe75c4 178 PIRSF PIRSF002070 2 161 1.4E-40 T 28-03-2018 WM46_RS15660 106c4d81d191b0c1d0c5b037fcfe75c4 178 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 39.379 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM46_RS15660 106c4d81d191b0c1d0c5b037fcfe75c4 178 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 163 4.0E-58 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM46_RS05995 9a4ad6d194acaa1c3be17b399a3d8667 849 Pfam PF13953 PapC C-terminal domain 763 825 1.6E-20 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS05995 9a4ad6d194acaa1c3be17b399a3d8667 849 SUPERFAMILY SSF141729 37 163 1.44E-24 T 28-03-2018 WM46_RS05995 9a4ad6d194acaa1c3be17b399a3d8667 849 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 312 322 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS05995 9a4ad6d194acaa1c3be17b399a3d8667 849 Pfam PF00577 Outer membrane usher protein 201 754 3.5E-167 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS05995 9a4ad6d194acaa1c3be17b399a3d8667 849 Pfam PF13954 PapC N-terminal domain 39 186 7.9E-37 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS14275 ad4bcf56756eb3c7690ae548ae6ac3d2 468 Gene3D G3DSA:1.20.1250.20 213 456 6.2E-17 T 28-03-2018 WM46_RS14275 ad4bcf56756eb3c7690ae548ae6ac3d2 468 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 446 1.9E-127 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS14275 ad4bcf56756eb3c7690ae548ae6ac3d2 468 SUPERFAMILY SSF103473 13 426 5.62E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS14275 ad4bcf56756eb3c7690ae548ae6ac3d2 468 Gene3D G3DSA:1.20.1250.20 12 212 1.8E-18 T 28-03-2018 WM46_RS14275 ad4bcf56756eb3c7690ae548ae6ac3d2 468 Pfam PF13347 MFS/sugar transport protein 13 432 6.9E-107 T 28-03-2018 WM46_RS24045 e36c03eb6dced3597266339fb1525757 137 ProDom PD032475 DNA POLYMERASE PSI SUBUNIT III TRANSFERASE NUCLEOTIDYLTRANSFERASE III 3D-STRUCTURE DNA-DIRECTED 34 125 6.0E-40 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS24045 e36c03eb6dced3597266339fb1525757 137 PIRSF PIRSF029225 2 131 1.9E-46 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS24045 e36c03eb6dced3597266339fb1525757 137 Gene3D G3DSA:3.40.50.10220 35 129 1.5E-32 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS24045 e36c03eb6dced3597266339fb1525757 137 Pfam PF03603 DNA polymerase III psi subunit 3 127 7.6E-43 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS24045 e36c03eb6dced3597266339fb1525757 137 TIGRFAM TIGR00664 DNA_III_psi: DNA polymerase III, psi subunit 1 125 1.1E-56 T 28-03-2018 IPR018382 DNA polymerase III, psi subunit, subgroup GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS24045 e36c03eb6dced3597266339fb1525757 137 SUPERFAMILY SSF102220 27 135 2.62E-32 T 28-03-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 WM46_RS09635 5b3b4c99252429a370f8acdfc60d7dce 209 SUPERFAMILY SSF159894 13 107 6.8E-27 T 28-03-2018 WM46_RS09635 5b3b4c99252429a370f8acdfc60d7dce 209 Gene3D G3DSA:1.10.150.20 117 195 2.6E-20 T 28-03-2018 WM46_RS09635 5b3b4c99252429a370f8acdfc60d7dce 209 Gene3D G3DSA:3.30.1460.30 7 108 8.0E-18 T 28-03-2018 WM46_RS09635 5b3b4c99252429a370f8acdfc60d7dce 209 Pfam PF04993 TfoX N-terminal domain 14 106 5.4E-24 T 28-03-2018 IPR007076 TfoX, N-terminal WM46_RS09635 5b3b4c99252429a370f8acdfc60d7dce 209 Pfam PF04994 TfoX C-terminal domain 116 194 1.7E-25 T 28-03-2018 IPR007077 TfoX, C-terminal WM46_RS09635 5b3b4c99252429a370f8acdfc60d7dce 209 PIRSF PIRSF028788 1 206 4.9E-56 T 28-03-2018 IPR026256 Transcriptional regulator, TfoX/Sxy-type WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 336 1.1E-44 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 16 182 2.2E-57 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 Gene3D G3DSA:3.40.50.1220 197 350 1.1E-49 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 540 4.9E-48 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 SUPERFAMILY SSF52518 368 562 9.54E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 SUPERFAMILY SSF52467 167 363 2.62E-56 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 SUPERFAMILY SSF52518 8 190 1.38E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 Gene3D G3DSA:3.40.50.970 10 196 3.7E-60 T 28-03-2018 WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 Gene3D G3DSA:3.40.50.970 351 553 2.9E-51 T 28-03-2018 WM46_RS19805 ecfd718359225821d72ebc4cfe5c580b 564 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 16 563 3.5E-202 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 Pfam PF09339 IclR helix-turn-helix domain 10 59 1.3E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 SMART SM00346 8 95 6.7E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 SUPERFAMILY SSF55781 70 250 2.39E-50 T 28-03-2018 IPR029016 GAF domain-like WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 Pfam PF01614 Bacterial transcriptional regulator 123 247 1.6E-34 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 Gene3D G3DSA:3.30.450.40 81 251 4.1E-50 T 28-03-2018 IPR029016 GAF domain-like WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 SUPERFAMILY SSF46785 8 79 1.08E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18005 c8ff837f520624e6f75c883c7e780d80 251 Gene3D G3DSA:1.10.10.10 2 80 8.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17705 1180ac75d5f8f76f2c61f9f64e1bb6f5 200 Gene3D G3DSA:1.10.3290.10 22 198 6.0E-21 T 28-03-2018 IPR003812 Fido domain WM46_RS17705 1180ac75d5f8f76f2c61f9f64e1bb6f5 200 Pfam PF02661 Fic/DOC family 58 152 7.0E-14 T 28-03-2018 IPR003812 Fido domain WM46_RS17705 1180ac75d5f8f76f2c61f9f64e1bb6f5 200 SUPERFAMILY SSF140931 46 196 3.14E-28 T 28-03-2018 IPR003812 Fido domain WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 1.8E-23 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 269 32.755 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 SUPERFAMILY SSF53223 2 101 8.63E-32 T 28-03-2018 WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 Gene3D G3DSA:3.40.50.720 111 272 3.2E-31 T 28-03-2018 WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 Gene3D G3DSA:3.40.50.10860 1 110 1.1E-37 T 28-03-2018 WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 270 1.7E-107 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 SUPERFAMILY SSF51735 102 268 1.5E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17350 e387473dc7a7e4e0b3c09ea3f46e1154 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 190 6.0E-10 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 SUPERFAMILY SSF117457 361 536 1.44E-62 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 Pfam PF05681 Fumarate hydratase (Fumerase) 51 326 1.1E-85 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 Pfam PF05683 Fumarase C-terminus 332 537 1.6E-94 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 372 537 2.0E-62 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 76 325 2.6E-30 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 PIRSF PIRSF001394 30 548 1.5E-237 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 Gene3D G3DSA:3.20.130.10 359 536 3.1E-68 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS07380 7dbe992f0a86a842497acb3aa241a96f 548 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS18170 1ceaa143dcd6fcc75c189e876c731c2f 222 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS18170 1ceaa143dcd6fcc75c189e876c731c2f 222 SMART SM00382 27 214 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18170 1ceaa143dcd6fcc75c189e876c731c2f 222 Gene3D G3DSA:3.40.50.300 1 220 4.2E-61 T 28-03-2018 WM46_RS18170 1ceaa143dcd6fcc75c189e876c731c2f 222 Pfam PF00005 ABC transporter 18 165 1.8E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18170 1ceaa143dcd6fcc75c189e876c731c2f 222 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 6.0E-93 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 WM46_RS18170 1ceaa143dcd6fcc75c189e876c731c2f 222 SUPERFAMILY SSF52540 1 216 2.87E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 SUPERFAMILY SSF53062 574 664 3.31E-10 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Gene3D G3DSA:1.10.10.10 2 73 2.9E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Gene3D G3DSA:3.40.50.300 97 322 1.6E-24 T 28-03-2018 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 SUPERFAMILY SSF52540 111 346 2.63E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Pfam PF00874 PRD domain 848 930 2.7E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 SUPERFAMILY SSF63520 465 557 4.19E-5 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Gene3D G3DSA:3.40.50.510 560 692 9.8E-14 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 SMART SM00382 133 282 2.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Pfam PF00158 Sigma-54 interaction domain 111 274 7.5E-47 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Gene3D G3DSA:3.40.50.2300 705 802 1.1E-5 T 28-03-2018 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 SUPERFAMILY SSF63520 829 930 1.7E-9 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Gene3D G3DSA:1.10.1790.10 836 932 5.0E-8 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Gene3D G3DSA:1.10.1790.10 464 559 1.1E-4 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS19925 f63ea9c117a0f217dc06f4f58dea7e8d 932 Pfam PF03610 PTS system fructose IIA component 574 653 4.6E-5 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS04910 399d9295c28a2f738ea0b193ad9c85b0 95 Pfam PF13974 YebO-like protein 17 95 2.1E-31 T 28-03-2018 IPR025594 YebO-like protein WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 SUPERFAMILY SSF160240 231 292 4.32E-8 T 28-03-2018 WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 Hamap MF_00552 Zinc transporter ZitB [zitB]. 3 312 64.903 T 28-03-2018 IPR023500 Zinc transporter ZitB GO:0005385|GO:0006829|GO:0016020 WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 Pfam PF01545 Cation efflux family 21 213 8.2E-51 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 Gene3D G3DSA:1.20.1510.10 17 213 1.5E-62 T 28-03-2018 WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 293 3.6E-97 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 Gene3D G3DSA:3.30.70.1350 216 293 3.4E-10 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain WM46_RS10755 ae79146fdf4eeea3a18245e132386563 313 SUPERFAMILY SSF161111 16 214 5.89E-60 T 28-03-2018 WM46_RS13870 ca93f30e08c20d5d7582c28dfb9f4c75 72 Pfam PF06786 Uncharacterised protein family (UPF0253) 8 71 1.4E-34 T 28-03-2018 IPR009624 Uncharacterised protein family UPF0253 WM46_RS13870 ca93f30e08c20d5d7582c28dfb9f4c75 72 Hamap MF_01064 UPF0253 protein YaeP [yaeP]. 7 72 26.775 T 28-03-2018 IPR009624 Uncharacterised protein family UPF0253 WM46_RS13870 ca93f30e08c20d5d7582c28dfb9f4c75 72 ProDom PD054643 UPF0253 YAEP CYTOPLASMIC VP2335 YPO1064.1/Y3113/YP2785 VC0872 VV2574 PBPRA2947 VV11836 7 72 7.0E-30 T 28-03-2018 IPR009624 Uncharacterised protein family UPF0253 WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 111 3.9E-30 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 229 1.2E-96 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 Gene3D G3DSA:1.10.1060.10 107 242 1.6E-26 T 28-03-2018 WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 SUPERFAMILY SSF46548 107 229 6.98E-31 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 Gene3D G3DSA:3.10.20.30 1 106 1.5E-28 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 Pfam PF13183 4Fe-4S dicluster domain 146 219 2.9E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS22805 95f33cd7b85d64b45ddf4bdc0e2730ce 244 SUPERFAMILY SSF54292 4 106 8.7E-29 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 Gene3D G3DSA:3.20.20.70 1 336 1.6E-77 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 PIRSF PIRSF000164 11 336 9.1E-96 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 292 312 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 2 336 51.277 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 Pfam PF01180 Dihydroorotate dehydrogenase 47 335 2.6E-92 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 SUPERFAMILY SSF51395 1 334 4.0E-104 T 28-03-2018 WM46_RS09705 df27857980ae8d4a866511892c253f0f 336 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 3 336 6.3E-167 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 WM46_RS21000 f7b21eb9893374ade085e42dc00d9bc0 258 SUPERFAMILY SSF53633 1 256 1.44E-61 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS21000 f7b21eb9893374ade085e42dc00d9bc0 258 PIRSF PIRSF000728 1 258 5.2E-73 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS21000 f7b21eb9893374ade085e42dc00d9bc0 258 Gene3D G3DSA:3.40.1160.10 1 258 2.4E-46 T 28-03-2018 WM46_RS21000 f7b21eb9893374ade085e42dc00d9bc0 258 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 258 26.915 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS21000 f7b21eb9893374ade085e42dc00d9bc0 258 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 234 2.1E-76 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 WM46_RS21000 f7b21eb9893374ade085e42dc00d9bc0 258 Pfam PF00696 Amino acid kinase family 5 235 1.1E-38 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS13720 f53ee2de96d65ca971bdf2a43c01df38 192 SUPERFAMILY SSF53697 1 189 3.64E-52 T 28-03-2018 WM46_RS13720 f53ee2de96d65ca971bdf2a43c01df38 192 Pfam PF13580 SIS domain 12 146 6.3E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS13720 f53ee2de96d65ca971bdf2a43c01df38 192 Gene3D G3DSA:3.40.50.10490 1 192 2.9E-42 T 28-03-2018 WM46_RS13720 f53ee2de96d65ca971bdf2a43c01df38 192 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 38.899 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 WM46_RS13720 f53ee2de96d65ca971bdf2a43c01df38 192 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 35 187 4.8E-85 T 28-03-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 WM46_RS14320 acfe72dbbdc55c5f8f829cbeeb66c5d5 206 Gene3D G3DSA:3.40.50.300 1 206 6.6E-46 T 28-03-2018 WM46_RS14320 acfe72dbbdc55c5f8f829cbeeb66c5d5 206 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 196 27.63 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 WM46_RS14320 acfe72dbbdc55c5f8f829cbeeb66c5d5 206 Pfam PF01121 Dephospho-CoA kinase 4 177 6.9E-73 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 WM46_RS14320 acfe72dbbdc55c5f8f829cbeeb66c5d5 206 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 5 189 5.3E-67 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 WM46_RS14320 acfe72dbbdc55c5f8f829cbeeb66c5d5 206 SUPERFAMILY SSF52540 1 190 2.03E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 SUPERFAMILY SSF53850 27 516 4.52E-126 T 28-03-2018 WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 68 433 1.4E-89 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 Gene3D G3DSA:3.90.76.10 35 179 8.6E-32 T 28-03-2018 WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 Gene3D G3DSA:3.40.190.10 180 277 6.2E-25 T 28-03-2018 WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 TIGRFAM TIGR02294 nickel_nikA: nickel ABC transporter, nickel/metallophore periplasmic binding protein 22 520 5.3E-244 T 28-03-2018 IPR011980 Nickel ABC transporter, substrate-binding protein NikA GO:0015675|GO:0016151|GO:0020037 WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 Gene3D G3DSA:3.10.105.10 278 493 1.6E-49 T 28-03-2018 WM46_RS20855 bb523c5c51b25c48deffe8bd2e5d58bc 524 PIRSF PIRSF002741 17 519 2.5E-88 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 WM46_RS10650 1b6dc4184bd0deabd4e6d43bdede5e45 229 Gene3D G3DSA:1.10.3720.10 4 227 1.3E-38 T 28-03-2018 WM46_RS10650 1b6dc4184bd0deabd4e6d43bdede5e45 229 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 220 5.2E-72 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 WM46_RS10650 1b6dc4184bd0deabd4e6d43bdede5e45 229 SUPERFAMILY SSF161098 6 219 2.62E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10650 1b6dc4184bd0deabd4e6d43bdede5e45 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 219 2.9E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01670 d3b6a9ef6a6f24d70bf9e413bad27ecd 184 Gene3D G3DSA:3.60.21.10 1 184 8.2E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS01670 d3b6a9ef6a6f24d70bf9e413bad27ecd 184 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 121 145 - T 28-03-2018 IPR020935 Phosphodiesterase YfcE, conserved site WM46_RS01670 d3b6a9ef6a6f24d70bf9e413bad27ecd 184 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 162 6.6E-25 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 WM46_RS01670 d3b6a9ef6a6f24d70bf9e413bad27ecd 184 SUPERFAMILY SSF56300 1 164 6.38E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS01670 d3b6a9ef6a6f24d70bf9e413bad27ecd 184 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 170 1.8E-45 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 WM46_RS21405 880e806901ff1456397294cfc0677eb2 274 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 4 273 7.2E-142 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS21405 880e806901ff1456397294cfc0677eb2 274 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 5 273 1.1E-104 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 73 1.0E-17 T 28-03-2018 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 Gene3D G3DSA:3.40.50.720 290 365 6.1E-12 T 28-03-2018 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 Gene3D G3DSA:3.40.50.720 1 289 1.4E-39 T 28-03-2018 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 Pfam PF03275 UDP-galactopyranose mutase 148 347 3.4E-79 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 4 363 1.5E-129 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 SUPERFAMILY SSF51971 332 361 1.47E-50 T 28-03-2018 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 SUPERFAMILY SSF51971 1 264 1.47E-50 T 28-03-2018 WM46_RS02985 fc474db9b13e660b4caa3b185bc8bb4a 366 SUPERFAMILY SSF54373 246 314 5.89E-24 T 28-03-2018 WM46_RS14290 58e656a0c00cb54c325d21c2c3260d5c 187 SMART SM00644 16 166 4.2E-59 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS14290 58e656a0c00cb54c325d21c2c3260d5c 187 Gene3D G3DSA:3.40.80.10 1 187 2.4E-55 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS14290 58e656a0c00cb54c325d21c2c3260d5c 187 SUPERFAMILY SSF55846 2 180 3.14E-69 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS14290 58e656a0c00cb54c325d21c2c3260d5c 187 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 51 167 2.1E-26 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 WM46_RS06020 b6818a27418e49fdf9bb8a3e788990bb 729 SUPERFAMILY SSF141729 7 60 2.49E-16 T 28-03-2018 WM46_RS06020 b6818a27418e49fdf9bb8a3e788990bb 729 Pfam PF00577 Outer membrane usher protein 84 637 9.0E-159 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS06020 b6818a27418e49fdf9bb8a3e788990bb 729 Pfam PF13953 PapC C-terminal domain 651 709 1.8E-18 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS06020 b6818a27418e49fdf9bb8a3e788990bb 729 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 196 206 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS06020 b6818a27418e49fdf9bb8a3e788990bb 729 Pfam PF13954 PapC N-terminal domain 9 69 7.3E-20 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 Pfam PF00574 Clp protease 26 205 6.8E-90 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 103 114 - T 28-03-2018 IPR018215 ClpP, Ser active site WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 Gene3D G3DSA:3.90.226.10 15 207 4.5E-48 T 28-03-2018 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 14 205 4.0E-112 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 PRINTS PR00127 Clp protease catalytic subunit P signature 124 143 1.7E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 PRINTS PR00127 Clp protease catalytic subunit P signature 181 200 1.7E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 PRINTS PR00127 Clp protease catalytic subunit P signature 32 47 1.7E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 PRINTS PR00127 Clp protease catalytic subunit P signature 103 120 1.7E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 PRINTS PR00127 Clp protease catalytic subunit P signature 72 92 1.7E-54 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 SUPERFAMILY SSF52096 23 206 6.63E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 125 138 - T 28-03-2018 IPR033135 ClpP, histidine active site WM46_RS12630 a3dbac2d1a5d097c9e4411ff6ac30753 207 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 206 45.028 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 WM46_RS03175 b735c21b5ce05af85aa8f367631180a3 298 Pfam PF04383 KilA-N domain 25 129 2.3E-16 T 28-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding WM46_RS03175 b735c21b5ce05af85aa8f367631180a3 298 SMART SM01252 23 131 2.4E-24 T 28-03-2018 IPR018004 KilA, N-terminal/APSES-type HTH, DNA-binding WM46_RS04330 ffd63fa2278d9a4859b6f396cd7de506 323 Hamap MF_01944 Lipid A biosynthesis myristoyltransferase [lpxM]. 4 310 53.709 T 28-03-2018 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 WM46_RS04330 ffd63fa2278d9a4859b6f396cd7de506 323 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 12 305 6.1E-110 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM46_RS04330 ffd63fa2278d9a4859b6f396cd7de506 323 PIRSF PIRSF026649 9 314 7.4E-105 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 WM46_RS04330 ffd63fa2278d9a4859b6f396cd7de506 323 TIGRFAM TIGR02208 lipid_A_msbB: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 10 314 2.8E-153 T 28-03-2018 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24 WM46_RS06965 a1d84322e9000c441a32e18743f5420b 350 Pfam PF05155 Phage X family 253 336 4.6E-31 T 28-03-2018 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 WM46_RS06965 a1d84322e9000c441a32e18743f5420b 350 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 2 338 1.3E-77 T 28-03-2018 IPR006516 Replication-associated protein G2P GO:0006260 WM46_RS06965 a1d84322e9000c441a32e18743f5420b 350 Pfam PF05144 Phage replication protein CRI 1 230 4.1E-68 T 28-03-2018 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 Pfam PF00106 short chain dehydrogenase 2 187 1.4E-53 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 Gene3D G3DSA:3.40.50.720 1 235 3.3E-58 T 28-03-2018 WM46_RS07155 cce782ca3d8f5ad47afd240c5b8a6e04 248 SUPERFAMILY SSF51735 2 231 2.6E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 SUPERFAMILY SSF81343 2 129 2.18E-36 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 7 126 1.3E-39 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 84 97 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 PIRSF PIRSF000178 1 129 8.5E-33 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 Gene3D G3DSA:1.20.1300.10 1 129 5.4E-28 T 28-03-2018 WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 9 33 - T 28-03-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11005 833cb0e705235579a264e019b70e37b3 129 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 123 1.6E-30 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 Pfam PF00462 Glutaredoxin 4 63 4.0E-24 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 SUPERFAMILY SSF52833 1 82 1.2E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 1.9E-36 T 28-03-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 PRINTS PR00160 Glutaredoxin signature 4 22 9.7E-18 T 28-03-2018 IPR014025 Glutaredoxin subgroup WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 PRINTS PR00160 Glutaredoxin signature 46 59 9.7E-18 T 28-03-2018 IPR014025 Glutaredoxin subgroup WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 PRINTS PR00160 Glutaredoxin signature 60 73 9.7E-18 T 28-03-2018 IPR014025 Glutaredoxin subgroup WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 28-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 WM46_RS20275 6910f7ce271f93b02b10d402d41ca2ff 83 Gene3D G3DSA:3.40.30.10 3 83 3.1E-27 T 28-03-2018 WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 Gene3D G3DSA:2.40.128.130 494 816 7.4E-56 T 28-03-2018 WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 Pfam PF03212 Pertactin 342 460 4.0E-15 T 28-03-2018 IPR004899 Pertactin, central region WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 SMART SM00869 536 805 2.4E-46 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 Gene3D G3DSA:2.160.20.20 2 467 1.5E-44 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 SUPERFAMILY SSF103515 502 816 4.84E-53 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 SUPERFAMILY SSF51126 65 461 5.34E-38 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 Pfam PF03797 Autotransporter beta-domain 539 794 8.3E-53 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS13195 dde4937a9894757ad5f6d381139c0cf6 816 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 360 816 8.2E-125 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS03620 b1896827eac46e2058bb50b00ff94f7b 271 Gene3D G3DSA:3.40.50.300 1 238 3.6E-60 T 28-03-2018 WM46_RS03620 b1896827eac46e2058bb50b00ff94f7b 271 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 12 199 5.7E-88 T 28-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 WM46_RS03620 b1896827eac46e2058bb50b00ff94f7b 271 SMART SM00382 26 212 1.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS03620 b1896827eac46e2058bb50b00ff94f7b 271 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS03620 b1896827eac46e2058bb50b00ff94f7b 271 SUPERFAMILY SSF52540 2 229 1.92E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03620 b1896827eac46e2058bb50b00ff94f7b 271 Pfam PF00005 ABC transporter 17 165 2.9E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09560 49b829d7ad141b35688f2ace20a3ceb9 400 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 3 387 1.3E-118 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 WM46_RS09560 49b829d7ad141b35688f2ace20a3ceb9 400 Gene3D G3DSA:3.40.640.10 44 279 1.9E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS09560 49b829d7ad141b35688f2ace20a3ceb9 400 Pfam PF00155 Aminotransferase class I and II 42 384 1.3E-36 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS09560 49b829d7ad141b35688f2ace20a3ceb9 400 Gene3D G3DSA:3.90.1150.10 280 388 4.7E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS09560 49b829d7ad141b35688f2ace20a3ceb9 400 SUPERFAMILY SSF53383 2 388 2.86E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS12495 cdafc5c6c41acdd76d4306ad0a0b8038 83 Gene3D G3DSA:1.10.1220.10 2 51 4.2E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS15780 2ea25185fb5b6c93b4538d716b4a0078 564 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 215 527 5.4E-96 T 28-03-2018 IPR005565 Haemolysin activator HlyB, C-terminal WM46_RS15780 2ea25185fb5b6c93b4538d716b4a0078 564 Gene3D G3DSA:3.10.20.310 85 157 2.7E-18 T 28-03-2018 WM46_RS15780 2ea25185fb5b6c93b4538d716b4a0078 564 Pfam PF08479 POTRA domain, ShlB-type 82 157 2.6E-24 T 28-03-2018 IPR013686 Polypeptide-transport-associated, ShlB-type WM46_RS15780 2ea25185fb5b6c93b4538d716b4a0078 564 Gene3D G3DSA:2.40.160.50 183 564 5.5E-49 T 28-03-2018 WM46_RS15780 2ea25185fb5b6c93b4538d716b4a0078 564 PIRSF PIRSF029745 6 564 3.1E-142 T 28-03-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 WM46_RS15780 2ea25185fb5b6c93b4538d716b4a0078 564 Pfam PF17287 POTRA domain 158 210 2.9E-19 T 28-03-2018 IPR035251 ShlB, POTRA domain WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 Pfam PF00571 CBS domain 274 325 3.8E-5 T 28-03-2018 IPR000644 CBS domain WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 Pfam PF00571 CBS domain 206 261 4.1E-5 T 28-03-2018 IPR000644 CBS domain WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 318 4.6E-130 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 SUPERFAMILY SSF53697 14 326 3.11E-65 T 28-03-2018 WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 Pfam PF01380 SIS domain 46 177 5.1E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 Gene3D G3DSA:3.40.50.10490 11 203 3.1E-54 T 28-03-2018 WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 PIRSF PIRSF004692 2 328 1.3E-134 T 28-03-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 WM46_RS16910 f75856c737f963219c15a5b64f605f3b 328 Gene3D G3DSA:3.10.580.10 204 326 4.8E-18 T 28-03-2018 WM46_RS24090 e0b0f08b6128787b11856598bffd9cc9 516 Gene3D G3DSA:3.20.70.20 169 474 1.8E-31 T 28-03-2018 WM46_RS24090 e0b0f08b6128787b11856598bffd9cc9 516 SUPERFAMILY SSF51998 24 470 4.58E-89 T 28-03-2018 WM46_RS24090 e0b0f08b6128787b11856598bffd9cc9 516 TIGRFAM TIGR04040 glycyl_YjjI: glycine radical enzyme, YjjI family 11 504 1.4E-235 T 28-03-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted WM46_RS24090 e0b0f08b6128787b11856598bffd9cc9 516 Pfam PF11230 Protein of unknown function (DUF3029) 22 504 4.5E-222 T 28-03-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted WM46_RS24090 e0b0f08b6128787b11856598bffd9cc9 516 PIRSF PIRSF028991 6 516 6.7E-275 T 28-03-2018 IPR016905 Glycyl radical enzyme, HI0521, predicted WM46_RS21395 8b55b2d6b8ed6123d1222e2d129e2aab 270 SUPERFAMILY SSF53223 3 102 1.27E-28 T 28-03-2018 WM46_RS21395 8b55b2d6b8ed6123d1222e2d129e2aab 270 Gene3D G3DSA:3.40.50.720 115 269 1.1E-28 T 28-03-2018 WM46_RS21395 8b55b2d6b8ed6123d1222e2d129e2aab 270 SUPERFAMILY SSF51735 103 263 5.22E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS21395 8b55b2d6b8ed6123d1222e2d129e2aab 270 Gene3D G3DSA:3.40.50.10860 18 114 4.5E-30 T 28-03-2018 WM46_RS21395 8b55b2d6b8ed6123d1222e2d129e2aab 270 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 23 90 1.1E-17 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 WM46_RS22255 fc0933dbe3ea7e03f58dbe00f7100267 205 SUPERFAMILY SSF54523 53 205 3.06E-36 T 28-03-2018 WM46_RS22255 fc0933dbe3ea7e03f58dbe00f7100267 205 Gene3D G3DSA:3.30.1690.10 57 205 1.7E-26 T 28-03-2018 WM46_RS22255 fc0933dbe3ea7e03f58dbe00f7100267 205 Pfam PF08805 PilS N terminal 58 201 1.2E-27 T 28-03-2018 IPR014911 Type 4 secretion system, PilS, N-terminal WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 ProSitePatterns PS00949 Autoinducer synthase family signature. 26 51 - T 28-03-2018 IPR018311 Autoinducer synthesis, conserved site KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 Gene3D G3DSA:3.40.630.30 6 208 1.1E-32 T 28-03-2018 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 SUPERFAMILY SSF55729 9 188 7.38E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 98 110 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 65 83 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 145 166 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 22 41 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 167 184 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 42 64 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 PRINTS PR01549 Autoinducer synthesis protein signature 123 144 1.6E-38 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS24560 49b4e6bb35c53cb8cd96c849e406dfaa 211 Pfam PF00765 Autoinducer synthase 17 191 1.6E-50 T 28-03-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 WM46_RS17900 4602e3e14ce5c691282bd3f2ce8323e2 227 SUPERFAMILY SSF53271 48 225 5.11E-36 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS17900 4602e3e14ce5c691282bd3f2ce8323e2 227 Gene3D G3DSA:3.40.50.2020 60 227 1.4E-23 T 28-03-2018 WM46_RS17900 4602e3e14ce5c691282bd3f2ce8323e2 227 Pfam PF00156 Phosphoribosyl transferase domain 169 224 1.0E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM46_RS02670 d9eff97f7e675df91734539a9367b477 202 Gene3D G3DSA:1.10.287.620 11 116 1.1E-4 T 28-03-2018 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 SUPERFAMILY SSF53901 271 391 9.61E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 1.6E-141 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 Pfam PF00108 Thiolase, N-terminal domain 4 262 7.9E-101 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 PIRSF PIRSF000429 1 392 9.3E-129 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 ProSitePatterns PS00099 Thiolases active site. 373 386 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 Gene3D G3DSA:3.40.47.10 1 183 2.6E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 Gene3D G3DSA:3.40.47.10 184 264 9.3E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 SUPERFAMILY SSF53901 3 269 2.98E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 Gene3D G3DSA:3.40.47.10 265 389 5.7E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS24765 4644392bb339fcd947ff91e4fd06c49c 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 3.4E-52 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 WM46_RS05625 d5d491cd21cd784e05eba72e9109125c 463 SUPERFAMILY SSF103473 20 461 4.71E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS05625 d5d491cd21cd784e05eba72e9109125c 463 Gene3D G3DSA:1.20.1250.20 244 463 8.2E-22 T 28-03-2018 WM46_RS05625 d5d491cd21cd784e05eba72e9109125c 463 Gene3D G3DSA:1.20.1250.20 20 238 1.7E-14 T 28-03-2018 WM46_RS05625 d5d491cd21cd784e05eba72e9109125c 463 Pfam PF07690 Major Facilitator Superfamily 45 422 4.3E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS05625 d5d491cd21cd784e05eba72e9109125c 463 TIGRFAM TIGR00886 2A0108: nitrite transporter 36 418 1.3E-114 T 28-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 WM46_RS23305 b7f599069739dcc9be562871b9e2eb9f 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 28-03-2018 IPR019897 RidA, conserved site WM46_RS23305 b7f599069739dcc9be562871b9e2eb9f 128 Gene3D G3DSA:3.30.1330.40 1 128 2.0E-45 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like WM46_RS23305 b7f599069739dcc9be562871b9e2eb9f 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 126 1.8E-53 T 28-03-2018 IPR006056 RidA family WM46_RS23305 b7f599069739dcc9be562871b9e2eb9f 128 Pfam PF01042 Endoribonuclease L-PSP 7 126 4.7E-45 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family WM46_RS23305 b7f599069739dcc9be562871b9e2eb9f 128 SUPERFAMILY SSF55298 4 127 2.51E-43 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 Gene3D G3DSA:3.40.50.720 45 253 1.7E-53 T 28-03-2018 WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 Gene3D G3DSA:3.40.50.720 2 44 6.4E-6 T 28-03-2018 WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 5.3E-56 T 28-03-2018 WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 7.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 SUPERFAMILY SSF51735 6 251 2.41E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 8.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24465 3b40ef712f6bb92674ceeb1cad107319 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 Gene3D G3DSA:3.30.70.20 28 55 0.013 T 28-03-2018 WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 Gene3D G3DSA:3.30.70.20 56 111 5.2E-17 T 28-03-2018 WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 SUPERFAMILY SSF54862 41 220 2.3E-68 T 28-03-2018 WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 Pfam PF13247 4Fe-4S dicluster domain 92 185 1.4E-29 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 Gene3D G3DSA:3.30.70.20 112 150 4.6E-20 T 28-03-2018 WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 Gene3D G3DSA:3.30.70.20 151 230 5.4E-24 T 28-03-2018 WM46_RS07775 71eb4911f3a6c419ba76dc2d99776a21 242 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 130 141 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 SUPERFAMILY SSF56655 1 259 2.36E-85 T 28-03-2018 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 3.5E-36 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 3.5E-36 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 3.5E-36 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 3.5E-36 T 28-03-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 2.6E-59 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 2.6E-59 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 2.6E-59 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 2.6E-59 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 2.6E-59 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 2.6E-59 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 Pfam PF00459 Inositol monophosphatase family 2 259 6.0E-74 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 Gene3D G3DSA:3.30.540.10 1 145 1.0E-50 T 28-03-2018 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 WM46_RS00605 6d86327b7f160dce29c62900658e3421 267 Gene3D G3DSA:3.40.190.80 146 267 5.2E-35 T 28-03-2018 WM46_RS19645 416a808f4fc13ba68768cf7d39153fcd 46 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.6E-27 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS19645 416a808f4fc13ba68768cf7d39153fcd 46 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS19645 416a808f4fc13ba68768cf7d39153fcd 46 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.163 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS19645 416a808f4fc13ba68768cf7d39153fcd 46 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 31 4.0E-11 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS19645 416a808f4fc13ba68768cf7d39153fcd 46 Pfam PF00468 Ribosomal protein L34 1 44 1.7E-24 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17655 b3e81bf9fc86585454fdabedee4b8972 328 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 230 271 - T 28-03-2018 IPR000952 AB hydrolase 4, conserved site WM46_RS17655 b3e81bf9fc86585454fdabedee4b8972 328 PIRSF PIRSF005211 4 328 3.4E-106 T 28-03-2018 IPR012020 AB hydrolase 4 family WM46_RS17655 b3e81bf9fc86585454fdabedee4b8972 328 SUPERFAMILY SSF53474 26 303 9.34E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS17655 b3e81bf9fc86585454fdabedee4b8972 328 Pfam PF00561 alpha/beta hydrolase fold 64 303 1.1E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS17655 b3e81bf9fc86585454fdabedee4b8972 328 Gene3D G3DSA:3.40.50.1820 36 323 6.7E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS09820 550d332d6182bee933094d9c1bcd29d9 60 SUPERFAMILY SSF158997 1 54 1.44E-19 T 28-03-2018 WM46_RS09820 550d332d6182bee933094d9c1bcd29d9 60 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 25.679 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 WM46_RS09820 550d332d6182bee933094d9c1bcd29d9 60 Pfam PF03966 Trm112p-like protein 2 41 1.7E-8 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 WM46_RS09820 550d332d6182bee933094d9c1bcd29d9 60 Gene3D G3DSA:2.20.25.10 8 60 9.4E-18 T 28-03-2018 WM46_RS14475 5a83e8bb024fef43890cd2e7dceab72a 392 TIGRFAM TIGR00899 2A0120: sugar efflux transporter 17 391 4.8E-170 T 28-03-2018 IPR004750 Sugar efflux GO:0008643|GO:0015542|GO:0016021 WM46_RS14475 5a83e8bb024fef43890cd2e7dceab72a 392 Pfam PF07690 Major Facilitator Superfamily 19 301 2.7E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14475 5a83e8bb024fef43890cd2e7dceab72a 392 Gene3D G3DSA:1.20.1250.20 211 390 2.4E-21 T 28-03-2018 WM46_RS14475 5a83e8bb024fef43890cd2e7dceab72a 392 Gene3D G3DSA:1.20.1250.20 11 203 2.2E-16 T 28-03-2018 WM46_RS14475 5a83e8bb024fef43890cd2e7dceab72a 392 SUPERFAMILY SSF103473 13 388 1.44E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS05775 054c4fa539af1f278bb9f2fc800b445c 109 Pfam PF04269 Protein of unknown function, DUF440 8 109 2.8E-46 T 28-03-2018 IPR007376 dsDNA mimic, putative WM46_RS05775 054c4fa539af1f278bb9f2fc800b445c 109 SUPERFAMILY SSF102816 3 109 4.45E-50 T 28-03-2018 IPR007376 dsDNA mimic, putative WM46_RS05775 054c4fa539af1f278bb9f2fc800b445c 109 ProDom PD020447 UPF0263 YCIU HD0986 VV1228 UNCHARACTERIZED 3D-STRUCTURE VV13059 BCR PM0536 VC1208 7 109 2.0E-52 T 28-03-2018 IPR007376 dsDNA mimic, putative WM46_RS05775 054c4fa539af1f278bb9f2fc800b445c 109 Gene3D G3DSA:3.10.450.140 10 108 2.9E-45 T 28-03-2018 IPR007376 dsDNA mimic, putative WM46_RS05775 054c4fa539af1f278bb9f2fc800b445c 109 PIRSF PIRSF004916 1 109 8.0E-57 T 28-03-2018 IPR007376 dsDNA mimic, putative WM46_RS05775 054c4fa539af1f278bb9f2fc800b445c 109 Hamap MF_00680 UPF0263 protein YciU [yciU]. 5 109 34.975 T 28-03-2018 IPR007376 dsDNA mimic, putative WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 437 34.664 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 Gene3D G3DSA:3.90.190.20 300 434 2.3E-33 T 28-03-2018 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 SUPERFAMILY SSF53623 95 297 1.31E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 Pfam PF08245 Mur ligase middle domain 110 280 2.3E-27 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 Gene3D G3DSA:3.40.50.720 1 94 1.4E-14 T 28-03-2018 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 369 1.8E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 Gene3D G3DSA:3.40.1190.10 95 299 1.3E-59 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 SUPERFAMILY SSF51984 3 94 1.01E-24 T 28-03-2018 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 435 7.4E-128 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 WM46_RS14390 3efafa5f319e975d32f91371865ff0ef 438 SUPERFAMILY SSF53244 299 437 5.95E-51 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 WM46_RS14325 2aaedbdc7b0980df6a03c6088eed3d0e 247 Gene3D G3DSA:1.10.3900.10 13 174 1.5E-62 T 28-03-2018 WM46_RS14325 2aaedbdc7b0980df6a03c6088eed3d0e 247 Hamap MF_01092 Cell division protein ZapD [zapD]. 4 247 33.067 T 28-03-2018 IPR009777 Cell division protein ZapD WM46_RS14325 2aaedbdc7b0980df6a03c6088eed3d0e 247 Gene3D G3DSA:2.60.440.10 175 247 4.4E-27 T 28-03-2018 IPR027462 Z ring-associated protein D, C-terminal domain WM46_RS14325 2aaedbdc7b0980df6a03c6088eed3d0e 247 SUPERFAMILY SSF160950 3 247 4.45E-92 T 28-03-2018 IPR009777 Cell division protein ZapD WM46_RS14325 2aaedbdc7b0980df6a03c6088eed3d0e 247 Pfam PF07072 Cell division protein 19 225 6.7E-78 T 28-03-2018 IPR009777 Cell division protein ZapD WM46_RS03085 c525e07ebecbae2ac98b36786edebb24 393 Pfam PF13356 Arm DNA-binding domain 4 84 2.4E-13 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS03085 c525e07ebecbae2ac98b36786edebb24 393 Gene3D G3DSA:1.10.150.130 91 189 1.2E-7 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS03085 c525e07ebecbae2ac98b36786edebb24 393 Pfam PF00589 Phage integrase family 207 367 8.5E-16 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS03085 c525e07ebecbae2ac98b36786edebb24 393 Gene3D G3DSA:1.10.443.10 204 377 1.2E-22 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS03085 c525e07ebecbae2ac98b36786edebb24 393 SUPERFAMILY SSF56349 96 376 2.55E-41 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS07650 53fb7e2d911fa03866298f3365930e99 457 Hamap MF_00400 Multidrug resistance protein MdtK [mdtK]. 1 457 53.373 T 28-03-2018 IPR022913 Multidrug resistance protein MdtK WM46_RS07650 53fb7e2d911fa03866298f3365930e99 457 PIRSF PIRSF006603 4 455 4.1E-59 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS07650 53fb7e2d911fa03866298f3365930e99 457 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 422 3.4E-124 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS07650 53fb7e2d911fa03866298f3365930e99 457 Pfam PF01554 MatE 244 405 3.2E-37 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS07650 53fb7e2d911fa03866298f3365930e99 457 Pfam PF01554 MatE 17 177 6.3E-41 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS18655 ad788ced67b8378e2b69ae8872f0ecfc 104 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 83 1.6E-8 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS18655 ad788ced67b8378e2b69ae8872f0ecfc 104 SUPERFAMILY SSF52794 1 94 1.74E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS18655 ad788ced67b8378e2b69ae8872f0ecfc 104 Gene3D G3DSA:3.40.50.2300 1 98 3.2E-17 T 28-03-2018 WM46_RS03440 6f039918461a9ed3615b4ddfdea15083 116 PIRSF PIRSF012296 1 116 1.1E-58 T 28-03-2018 IPR009307 Ethanolamine utilisation EutS GO:0031469 WM46_RS03440 6f039918461a9ed3615b4ddfdea15083 116 Pfam PF00936 BMC domain 45 107 1.0E-12 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03440 6f039918461a9ed3615b4ddfdea15083 116 SUPERFAMILY SSF143414 44 112 7.98E-15 T 28-03-2018 WM46_RS03440 6f039918461a9ed3615b4ddfdea15083 116 SMART SM00877 44 116 1.2E-18 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS06655 d6f1cd06768da9bcbb5f9fbc30836067 480 PIRSF PIRSF006060 23 479 4.1E-63 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS06655 d6f1cd06768da9bcbb5f9fbc30836067 480 ProSitePatterns PS00218 Amino acid permeases signature. 59 89 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS06655 d6f1cd06768da9bcbb5f9fbc30836067 480 Pfam PF00324 Amino acid permease 35 476 1.8E-126 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS23385 63f3e26f6c366430680324fe12bac491 254 PIRSF PIRSF020736 1 253 6.9E-91 T 28-03-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 WM46_RS23385 63f3e26f6c366430680324fe12bac491 254 Gene3D G3DSA:1.20.1260.10 3 254 3.4E-70 T 28-03-2018 IPR012347 Ferritin-related WM46_RS23385 63f3e26f6c366430680324fe12bac491 254 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 5 248 6.1E-120 T 28-03-2018 IPR010386 tRNA-hydroxylase MiaE GO:0006400|GO:0045301 WM46_RS23385 63f3e26f6c366430680324fe12bac491 254 SUPERFAMILY SSF47240 7 57 1.51E-72 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS23385 63f3e26f6c366430680324fe12bac491 254 SUPERFAMILY SSF47240 105 252 1.51E-72 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 Gene3D G3DSA:1.10.150.240 18 77 2.3E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 Pfam PF13419 Haloacid dehalogenase-like hydrolase 49 184 6.6E-13 T 28-03-2018 IPR023214 HAD-like domain WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 SUPERFAMILY SSF56784 3 193 6.01E-44 T 28-03-2018 IPR023214 HAD-like domain WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 63 184 1.7E-19 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 2.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 2.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 2.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 2.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS18760 270a0d51d078aabc40e44540ee05b2d0 199 Gene3D G3DSA:3.40.50.1000 78 194 9.7E-23 T 28-03-2018 IPR023214 HAD-like domain WM46_RS24680 fe6b465aca7a449d9dbca1f80bb4d89e 282 SMART SM00862 25 103 7.6E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS24680 fe6b465aca7a449d9dbca1f80bb4d89e 282 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 102 3.7E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS24680 fe6b465aca7a449d9dbca1f80bb4d89e 282 SUPERFAMILY SSF46894 24 103 1.19E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS24680 fe6b465aca7a449d9dbca1f80bb4d89e 282 Gene3D G3DSA:1.10.10.10 4 109 9.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 337 356 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 37 56 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 182 204 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 282 301 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 316 334 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 148 168 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 10 33 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 82 102 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 PRINTS PR00166 Aromatic amino acid permease signature 221 240 6.2E-92 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 Pfam PF03222 Tryptophan/tyrosine permease family 3 390 1.2E-142 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 TIGRFAM TIGR00837 araaP: aromatic amino acid transport protein 7 384 1.1E-146 T 28-03-2018 IPR013059 Tryptophan/tyrosine transporter GO:0005887|GO:0015173|GO:0015801 WM46_RS04020 46309b6e18cf968845d9b20f714deee9 403 ProSitePatterns PS00594 Aromatic amino acids permeases signature. 17 33 - T 28-03-2018 IPR013061 Tryptophan/tryrosine permease, conserved site WM46_RS01990 9299f0c11ebfd463b4f2e9afcff00f21 84 Gene3D G3DSA:3.10.20.30 1 84 3.6E-15 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS01990 9299f0c11ebfd463b4f2e9afcff00f21 84 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 77 1.5E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS01990 9299f0c11ebfd463b4f2e9afcff00f21 84 SUPERFAMILY SSF54292 3 83 1.84E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 WM46_RS01990 9299f0c11ebfd463b4f2e9afcff00f21 84 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 Gene3D G3DSA:1.10.10.10 1 76 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 SMART SM00345 15 74 3.4E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 SUPERFAMILY SSF46785 5 78 1.72E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 Pfam PF07702 UTRA domain 99 234 1.3E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 SMART SM00866 96 235 8.3E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 Gene3D G3DSA:3.40.1410.10 77 236 1.7E-27 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 SUPERFAMILY SSF64288 62 234 7.07E-28 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS18475 4820d2c79be6ae49214dc4082ab7d87c 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.6E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 Gene3D G3DSA:3.90.650.10 145 322 3.9E-48 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 322 1.9E-118 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 300 8.0E-9 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 PIRSF PIRSF005303 1 322 7.2E-88 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 138 5.0E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 319 32.026 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 SUPERFAMILY SSF55326 4 138 1.02E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 Gene3D G3DSA:3.30.1330.10 1 144 5.0E-36 T 28-03-2018 IPR016188 PurM-like, N-terminal domain WM46_RS12760 bb67d935c713dee2b1153a2a6428d5c1 325 SUPERFAMILY SSF56042 143 309 5.08E-40 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain WM46_RS07980 60a5dc02ac48039075f3e7fe9f6654bc 237 Gene3D G3DSA:3.20.20.450 8 225 7.2E-13 T 28-03-2018 IPR001633 EAL domain WM46_RS07980 60a5dc02ac48039075f3e7fe9f6654bc 237 SUPERFAMILY SSF141868 12 223 5.23E-9 T 28-03-2018 IPR001633 EAL domain WM46_RS07980 60a5dc02ac48039075f3e7fe9f6654bc 237 Pfam PF00563 EAL domain 12 222 5.6E-10 T 28-03-2018 IPR001633 EAL domain WM46_RS21945 36d0f725dfdc93d06c5edf62c420c5fb 547 SUPERFAMILY SSF53649 239 531 7.41E-20 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS21945 36d0f725dfdc93d06c5edf62c420c5fb 547 Gene3D G3DSA:3.40.720.10 220 542 1.1E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS21945 36d0f725dfdc93d06c5edf62c420c5fb 547 Pfam PF08019 Domain of unknown function (DUF1705) 59 209 1.3E-41 T 28-03-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 WM46_RS21945 36d0f725dfdc93d06c5edf62c420c5fb 547 Pfam PF00884 Sulfatase 238 527 4.9E-54 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS20035 d7bbf207f1ae015f0855adf5b796d464 391 Gene3D G3DSA:1.20.1250.20 2 202 1.4E-20 T 28-03-2018 WM46_RS20035 d7bbf207f1ae015f0855adf5b796d464 391 Gene3D G3DSA:1.20.1250.20 203 385 1.9E-19 T 28-03-2018 WM46_RS20035 d7bbf207f1ae015f0855adf5b796d464 391 SUPERFAMILY SSF103473 4 382 2.35E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS20035 d7bbf207f1ae015f0855adf5b796d464 391 Pfam PF07690 Major Facilitator Superfamily 8 350 1.2E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 SUPERFAMILY SSF89447 1 135 1.67E-45 T 28-03-2018 WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 Pfam PF02381 MraZ protein, putative antitoxin-like 77 137 2.3E-20 T 28-03-2018 IPR020603 MraZ domain WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 Pfam PF02381 MraZ protein, putative antitoxin-like 1 75 2.3E-24 T 28-03-2018 IPR020603 MraZ domain WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 Gene3D G3DSA:2.10.260.10 81 127 0.001 T 28-03-2018 WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 Gene3D G3DSA:2.10.260.10 3 39 0.037 T 28-03-2018 WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 139 3.0E-77 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 152 1.0E-65 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 WM46_RS14425 00fc477d1bb688fadd6e1774cfe61a1f 152 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 152 57.801 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 WM46_RS16445 06840ce821bfdaf3367c736d28a03fae 130 Pfam PF07681 DoxX 9 87 7.4E-18 T 28-03-2018 IPR032808 DoxX family WM46_RS04580 453a6dc3478391876242630461cdef38 85 Pfam PF15944 Domain of unknown function (DUF4752) 1 83 3.0E-38 T 28-03-2018 IPR031858 Protein of unknown function DUF4752 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 220 232 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 115 129 9.4E-34 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 9.4E-34 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 165 177 9.4E-34 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 43 52 9.4E-34 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 103 115 9.4E-34 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 233 243 9.4E-34 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 Pfam PF00813 FliP family 48 239 7.5E-80 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 172 192 2.9E-68 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 64 84 2.9E-68 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 217 242 2.9E-68 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 45 64 2.9E-68 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 193 214 2.9E-68 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 84 103 2.9E-68 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 47 243 4.5E-95 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 WM46_RS03785 b541a708806d87d5c0280852df3991c9 245 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 172 187 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 WM46_RS18650 a24b0c31513dcf4920bee3dc519a0790 455 Pfam PF03611 PTS system sugar-specific permease component 12 406 2.5E-120 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 WM46_RS01400 7a29090f5543a4ea4da63777bf300e92 254 SUPERFAMILY SSF161098 14 234 1.3E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01400 7a29090f5543a4ea4da63777bf300e92 254 Gene3D G3DSA:1.10.3720.10 2 254 1.5E-46 T 28-03-2018 WM46_RS01400 7a29090f5543a4ea4da63777bf300e92 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 248 9.5E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS19620 0919be6da70878ce375e2d4df39a81ee 309 SUPERFAMILY SSF51395 48 287 4.76E-6 T 28-03-2018 WM46_RS19620 0919be6da70878ce375e2d4df39a81ee 309 Gene3D G3DSA:3.20.20.70 13 197 6.4E-11 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS19620 0919be6da70878ce375e2d4df39a81ee 309 Gene3D G3DSA:3.20.20.70 198 304 0.11 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS02390 788f8e1e5a1f9eadcb5e3dbfa920abd3 311 Gene3D G3DSA:3.40.1790.10 6 311 4.7E-138 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 WM46_RS02390 788f8e1e5a1f9eadcb5e3dbfa920abd3 311 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 15 309 43.549 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 WM46_RS02390 788f8e1e5a1f9eadcb5e3dbfa920abd3 311 Pfam PF04227 Indigoidine synthase A like protein 16 306 1.0E-130 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 WM46_RS02390 788f8e1e5a1f9eadcb5e3dbfa920abd3 311 SUPERFAMILY SSF110581 9 308 5.23E-117 T 28-03-2018 WM46_RS14770 9e0e14ac5bb0c5078f94feefce379fd7 188 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 8 17 - T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 WM46_RS14770 9e0e14ac5bb0c5078f94feefce379fd7 188 Pfam PF01184 GPR1/FUN34/yaaH family 4 176 1.2E-38 T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 WM46_RS03840 58c80906c34610ee995bded81e899f99 104 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 2 104 18.099 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 WM46_RS03840 58c80906c34610ee995bded81e899f99 104 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 2 104 7.0E-41 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 WM46_RS03840 58c80906c34610ee995bded81e899f99 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 68 84 2.9E-22 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 WM46_RS03840 58c80906c34610ee995bded81e899f99 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 33 49 2.9E-22 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 WM46_RS03840 58c80906c34610ee995bded81e899f99 104 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 89 102 2.9E-22 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 WM46_RS03840 58c80906c34610ee995bded81e899f99 104 Pfam PF02049 Flagellar hook-basal body complex protein FliE 17 104 6.1E-28 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 317 332 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 SMART SM00493 1 124 2.3E-31 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Pfam PF01131 DNA topoisomerase 158 593 1.3E-111 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 SMART SM00436 128 223 7.2E-38 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 SMART SM00437 280 558 9.8E-106 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 323 332 1.2E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 193 211 1.2E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 521 535 1.2E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 402 418 1.2E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 1.2E-25 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Gene3D G3DSA:1.10.460.10 157 351 3.7E-39 T 28-03-2018 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Gene3D G3DSA:1.10.460.10 482 608 4.9E-19 T 28-03-2018 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Hamap MF_00953 DNA topoisomerase 3 [topB]. 1 646 69.95 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Pfam PF01751 Toprim domain 3 135 3.8E-18 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Gene3D G3DSA:3.40.50.140 1 156 4.9E-40 T 28-03-2018 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 SUPERFAMILY SSF56712 1 607 6.54E-188 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 646 9.0E-303 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 WM46_RS08255 250bee67b6b24e5e3574d7d545459358 648 Gene3D G3DSA:2.70.20.10 364 481 2.0E-22 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 WM46_RS16170 7a004f999a3fb52d72400dd1680dca6c 222 Hamap MF_00932 Thiol:disulfide interchange protein DsbL [dsbL]. 1 222 60.836 T 28-03-2018 IPR028588 Thiol:disulfide interchange protein DsbL WM46_RS16170 7a004f999a3fb52d72400dd1680dca6c 222 SUPERFAMILY SSF52833 27 219 4.48E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS16170 7a004f999a3fb52d72400dd1680dca6c 222 Pfam PF01323 DSBA-like thioredoxin domain 48 201 2.2E-11 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 WM46_RS16170 7a004f999a3fb52d72400dd1680dca6c 222 Gene3D G3DSA:3.40.30.10 28 222 1.2E-30 T 28-03-2018 WM46_RS16170 7a004f999a3fb52d72400dd1680dca6c 222 PIRSF PIRSF001488 1 222 4.0E-26 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 123 4.1E-17 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 71 99 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 Gene3D G3DSA:1.20.5.1030 68 119 1.6E-18 T 28-03-2018 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 PRINTS PR01650 Bacterial translocase SecE signature 65 85 1.0E-41 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 PRINTS PR01650 Bacterial translocase SecE signature 109 125 1.0E-41 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 PRINTS PR01650 Bacterial translocase SecE signature 89 109 1.0E-41 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 PRINTS PR01650 Bacterial translocase SecE signature 44 65 1.0E-41 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 70 122 3.9E-20 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS21155 c0f2207e5597c0617c8b3ae7e591e417 127 Hamap MF_00422 Protein translocase subunit SecE [secE]. 67 121 13.188 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 WM46_RS22685 85a3438b32222bbe822263215b6d4416 196 Pfam PF01810 LysE type translocator 13 185 1.7E-12 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS04840 f8d5cb2d0b6e3ce6a2775e89dc7e8874 220 Pfam PF00149 Calcineurin-like phosphoesterase 18 148 1.2E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS04840 f8d5cb2d0b6e3ce6a2775e89dc7e8874 220 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 76 81 - T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 WM46_RS04840 f8d5cb2d0b6e3ce6a2775e89dc7e8874 220 Gene3D G3DSA:3.60.21.10 6 220 4.5E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS04840 f8d5cb2d0b6e3ce6a2775e89dc7e8874 220 SUPERFAMILY SSF56300 18 219 1.98E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 PIRSF PIRSF000538 2 542 4.5E-75 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 SUPERFAMILY SSF53067 279 533 4.94E-55 T 28-03-2018 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 Gene3D G3DSA:3.30.420.40 1 263 1.1E-66 T 28-03-2018 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 SUPERFAMILY SSF53067 4 263 1.75E-60 T 28-03-2018 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 Gene3D G3DSA:3.30.420.40 276 545 2.4E-66 T 28-03-2018 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 282 488 1.3E-41 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 TIGRFAM TIGR01315 5C_CHO_kinase: FGGY-family pentulose kinase 5 538 4.1E-211 T 28-03-2018 IPR006003 FGGY carbohydrate kinase, pentulose kinase GO:0005975|GO:0016773 WM46_RS00555 f2bc16b6079ba0fa43a828e127268496 545 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 262 3.7E-32 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS23785 55128d87c5b87674cc409143ef473cde 79 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 73 4.2E-21 T 28-03-2018 IPR018680 Protein of unknown function DUF2164 WM46_RS02555 ebce74905d077435f0d49a28d633a992 315 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 261 1.5E-87 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 WM46_RS02555 ebce74905d077435f0d49a28d633a992 315 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 6.4E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS02555 ebce74905d077435f0d49a28d633a992 315 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 6.4E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS02555 ebce74905d077435f0d49a28d633a992 315 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 6.4E-14 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 WM46_RS02555 ebce74905d077435f0d49a28d633a992 315 Gene3D G3DSA:3.40.710.10 16 314 2.1E-44 T 28-03-2018 WM46_RS02555 ebce74905d077435f0d49a28d633a992 315 SUPERFAMILY SSF56601 3 277 1.44E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 SUPERFAMILY SSF52374 6 286 9.29E-88 T 28-03-2018 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 6 270 2.5E-111 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 Gene3D G3DSA:3.40.50.620 124 222 1.7E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 2.3E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 186 194 2.3E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 2.3E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 170 180 2.3E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 2.3E-12 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 257 6.3E-47 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 Gene3D G3DSA:3.40.50.620 1 123 3.5E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS14095 c4bed01a35ce14a785d7124cb42761e9 298 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 6 290 41.159 T 28-03-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 WM46_RS23460 9f38ae84e66b267c45face913dc98329 180 Pfam PF01202 Shikimate kinase 12 165 1.2E-11 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS23460 9f38ae84e66b267c45face913dc98329 180 Gene3D G3DSA:3.40.50.300 4 175 4.6E-28 T 28-03-2018 WM46_RS23460 9f38ae84e66b267c45face913dc98329 180 SUPERFAMILY SSF52540 3 165 2.07E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23460 9f38ae84e66b267c45face913dc98329 180 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 167 1.3E-70 T 28-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 Gene3D G3DSA:2.30.38.10 348 430 2.6E-21 T 28-03-2018 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 SUPERFAMILY SSF56801 5 531 4.06E-124 T 28-03-2018 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 Gene3D G3DSA:3.40.50.980 193 347 8.4E-29 T 28-03-2018 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 520 2.5E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 Gene3D G3DSA:3.30.300.30 431 535 5.5E-23 T 28-03-2018 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 3 527 1.5E-272 T 28-03-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 Pfam PF00501 AMP-binding enzyme 36 437 6.6E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS11585 d375607b0bca3d8d70df5ea7a115027c 535 Gene3D G3DSA:3.40.50.980 23 192 5.9E-26 T 28-03-2018 WM46_RS09155 c64967256a5aab30e7247b68dfc3d247 75 Pfam PF13993 YccJ-like protein 9 75 2.0E-38 T 28-03-2018 IPR025600 YccJ-like protein WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 50 177 1.4E-38 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 SUPERFAMILY SSF56762 225 600 1.57E-119 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 329 600 4.7E-102 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 Gene3D G3DSA:1.10.645.10 211 413 4.8E-47 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 16 600 71.944 T 28-03-2018 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 211 600 41.775 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 SUPERFAMILY SSF143243 25 229 1.44E-57 T 28-03-2018 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 49 176 1.4E-42 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 215 600 2.7E-177 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 Gene3D G3DSA:1.10.645.10 414 596 9.5E-32 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 105 160 7.0E-26 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01770 c5c5781cf11121ea3169d4f95a170138 600 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 252 263 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 Gene3D G3DSA:1.10.580.10 28 368 1.0E-82 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 ProSitePatterns PS00480 Citrate synthase signature. 271 283 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PRINTS PR00143 Citrate synthase signature 139 152 1.8E-37 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PRINTS PR00143 Citrate synthase signature 211 239 1.8E-37 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PRINTS PR00143 Citrate synthase signature 341 355 1.8E-37 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PRINTS PR00143 Citrate synthase signature 264 284 1.8E-37 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PRINTS PR00143 Citrate synthase signature 321 337 1.8E-37 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PRINTS PR00143 Citrate synthase signature 189 204 1.8E-37 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 PIRSF PIRSF001369 15 389 5.5E-111 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 21 388 3.1E-167 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 SUPERFAMILY SSF48256 22 382 4.19E-123 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS13170 67be8544a09fecf8254b740ae2371d8f 389 Pfam PF00285 Citrate synthase, C-terminal domain 22 370 3.8E-115 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 WM46_RS22705 6b262726d3e82242914d92b88dcb9368 433 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 365 6.4E-145 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS22705 6b262726d3e82242914d92b88dcb9368 433 PIRSF PIRSF004539 1 433 1.4E-180 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS22705 6b262726d3e82242914d92b88dcb9368 433 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 433 8.6E-206 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 49 571 1.8E-231 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 Pfam PF01019 Gamma-glutamyltranspeptidase 64 572 1.6E-192 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 391 415 - T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 291 310 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 480 497 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 261 277 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 162 181 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 415 433 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 71 96 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 391 409 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 144 162 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 456 471 1.7E-81 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 WM46_RS18075 a3a36c6e48e81a9f2a9314a5a9c61517 580 SUPERFAMILY SSF56235 41 572 6.56E-199 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS18945 3ad0435e4fa443189ea5bf6e5e36023d 483 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 466 8.6E-130 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 WM46_RS18945 3ad0435e4fa443189ea5bf6e5e36023d 483 Pfam PF02386 Cation transport protein 37 477 3.1E-92 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 WM46_RS18945 3ad0435e4fa443189ea5bf6e5e36023d 483 PIRSF PIRSF006247 1 483 4.2E-185 T 28-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 WM46_RS02615 9f74f8abc3f9a7ebd4619056656e6e11 156 Pfam PF07308 Protein of unknown function (DUF1456) 4 70 1.2E-23 T 28-03-2018 IPR009921 Domain of unknown function DUF1456 WM46_RS02615 9f74f8abc3f9a7ebd4619056656e6e11 156 Pfam PF07308 Protein of unknown function (DUF1456) 86 151 4.1E-21 T 28-03-2018 IPR009921 Domain of unknown function DUF1456 WM46_RS09805 86895d3704ad556522558e14b6b259a5 259 Pfam PF02698 DUF218 domain 81 217 4.5E-28 T 28-03-2018 IPR003848 Domain of unknown function DUF218 WM46_RS09805 86895d3704ad556522558e14b6b259a5 259 Gene3D G3DSA:3.40.50.620 71 213 2.4E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11070 84e89734d72f84855838e4d18477baa1 247 Gene3D G3DSA:3.40.1390.30 110 218 2.4E-32 T 28-03-2018 WM46_RS11070 84e89734d72f84855838e4d18477baa1 247 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 234 8.3E-58 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 WM46_RS11070 84e89734d72f84855838e4d18477baa1 247 SUPERFAMILY SSF102705 1 246 9.94E-85 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 WM46_RS11070 84e89734d72f84855838e4d18477baa1 247 Gene3D G3DSA:3.40.1390.30 1 109 1.5E-28 T 28-03-2018 WM46_RS11070 84e89734d72f84855838e4d18477baa1 247 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 246 3.5E-82 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 306 329 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 43 58 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 SUPERFAMILY SSF118215 8 412 6.28E-122 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 Hamap MF_02063 Proton/glutamate-aspartate symporter [gltP]. 1 428 48.208 T 28-03-2018 IPR034703 Proton/glutamate-aspartate symporter GltP GO:0006835|GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 Pfam PF00375 Sodium:dicarboxylate symporter family 8 411 8.5E-116 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 365 385 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 338 357 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 303 329 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 6 26 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 1.5E-52 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS21810 a5a8a8029f4f4a41bf5a3c1da581d016 436 Gene3D G3DSA:1.10.3860.10 2 418 1.2E-124 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS12785 f21122f27116e15a6d08572fc0758f7e 179 Pfam PF11622 Protein of unknown function (DUF3251) 20 178 8.1E-78 T 28-03-2018 IPR021658 Domain of unknown function DUF3251 WM46_RS12785 f21122f27116e15a6d08572fc0758f7e 179 Gene3D G3DSA:2.60.40.1620 43 175 2.4E-55 T 28-03-2018 IPR021658 Domain of unknown function DUF3251 WM46_RS08235 5fe9f7f3d4185cf8de2e0fe3f97a774e 189 Gene3D G3DSA:1.20.1290.10 15 184 2.4E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS08235 5fe9f7f3d4185cf8de2e0fe3f97a774e 189 SUPERFAMILY SSF69118 15 180 3.96E-38 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS08235 5fe9f7f3d4185cf8de2e0fe3f97a774e 189 Pfam PF02627 Carboxymuconolactone decarboxylase family 59 126 1.1E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Gene3D G3DSA:3.50.50.60 196 227 1.1E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 442 458 5.6E-38 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 315 333 5.6E-38 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 468 490 5.6E-38 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 5.6E-38 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 357 375 5.6E-38 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PIRSF PIRSF000238 1 521 1.9E-262 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 345 365 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 SUPERFAMILY SSF52833 106 197 2.93E-24 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 SUPERFAMILY SSF52833 1 101 1.45E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 478 496 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 316 324 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 353 377 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 405 421 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 338 350 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 444 465 2.1E-66 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Gene3D G3DSA:3.50.50.60 341 438 1.1E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 517 1.8E-239 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Gene3D G3DSA:3.40.30.10 103 195 5.1E-8 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Pfam PF13192 Thioredoxin domain 126 194 5.5E-9 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Gene3D G3DSA:3.50.50.60 439 512 0.0058 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 503 5.9E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 SUPERFAMILY SSF51905 206 514 9.88E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Gene3D G3DSA:3.40.30.10 1 94 1.1E-27 T 28-03-2018 WM46_RS11535 4a40b4c7b2282e33fffe3be13d540ff4 521 Gene3D G3DSA:3.50.50.60 228 340 1.5E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS06435 af7e9ab1154db7fbd3524746b8b21198 74 Pfam PF04325 Protein of unknown function (DUF465) 19 66 4.7E-14 T 28-03-2018 IPR007420 Protein of unknown function DUF465 WM46_RS05280 ef46c91a12d7fe2b899fbeef8f0851ae 92 ProDom PD865043 PLASMID SPA-ORF10 3'REGION CYTOPLASMIC ORF-10 SPAS STY1854 44 92 2.0E-4 T 28-03-2018 IPR024753 Regulatory protein AriR GO:0042710|GO:0071229 WM46_RS05280 ef46c91a12d7fe2b899fbeef8f0851ae 92 Pfam PF10798 Biofilm development protein YmgB/AriR 33 91 5.0E-22 T 28-03-2018 IPR024753 Regulatory protein AriR GO:0042710|GO:0071229 WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 84 3.2E-32 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 Pfam PF01455 HupF/HypC family 1 71 4.8E-26 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 28-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 SUPERFAMILY SSF159127 1 86 5.76E-28 T 28-03-2018 WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 6.3E-23 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 62 74 6.3E-23 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 44 60 6.3E-23 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS25370 c1c2ea96a1add60a29f03b9c6850aa89 90 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 6.3E-23 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 300 395 6.2E-20 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 403 546 7.5E-39 T 28-03-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 301 316 6.5E-34 T 28-03-2018 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 429 448 6.5E-34 T 28-03-2018 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 356 368 6.5E-34 T 28-03-2018 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 322 340 6.5E-34 T 28-03-2018 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01413 Cytochrome c-type biogenesis protein NrfE signature 542 555 6.5E-34 T 28-03-2018 IPR003570 Cytochrome c-type biogenesis protein NrfE GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 142 164 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 277 293 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 63 89 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 193 219 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 115 132 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 227 247 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 293 312 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 257 277 1.8E-70 T 28-03-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS21790 6faac099fec9dd38edffc69f97543ad5 555 Pfam PF01578 Cytochrome C assembly protein 72 279 6.9E-46 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 WM46_RS02290 10dd76b038243548c3bb5ffa0e441eec 364 Gene3D G3DSA:1.10.3720.10 2 349 7.2E-36 T 28-03-2018 WM46_RS02290 10dd76b038243548c3bb5ffa0e441eec 364 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 152 359 2.5E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS02290 10dd76b038243548c3bb5ffa0e441eec 364 SUPERFAMILY SSF161098 131 346 3.27E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS11545 8f653c6a9fac47ba72b8c95b82bfc75b 248 SUPERFAMILY SSF52833 83 245 1.56E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS11545 8f653c6a9fac47ba72b8c95b82bfc75b 248 Gene3D G3DSA:3.10.450.70 24 86 4.0E-26 T 28-03-2018 WM46_RS11545 8f653c6a9fac47ba72b8c95b82bfc75b 248 Gene3D G3DSA:3.40.30.10 104 247 3.7E-20 T 28-03-2018 WM46_RS11545 8f653c6a9fac47ba72b8c95b82bfc75b 248 SUPERFAMILY SSF54423 19 78 3.4E-21 T 28-03-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal WM46_RS11545 8f653c6a9fac47ba72b8c95b82bfc75b 248 Pfam PF13098 Thioredoxin-like domain 112 244 7.8E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS23155 48d30e2cc567940d2a74d438cc8b0652 341 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 321 6.7E-49 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS23155 48d30e2cc567940d2a74d438cc8b0652 341 Gene3D G3DSA:1.10.3470.10 51 327 5.8E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS19735 60ec0b50c635b50560d752d0a15d4f98 488 Pfam PF00884 Sulfatase 4 321 2.0E-32 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS19735 60ec0b50c635b50560d752d0a15d4f98 488 Gene3D G3DSA:3.40.720.10 2 358 3.8E-52 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS19735 60ec0b50c635b50560d752d0a15d4f98 488 SUPERFAMILY SSF53649 4 373 7.61E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS19735 60ec0b50c635b50560d752d0a15d4f98 488 SUPERFAMILY SSF53649 428 468 7.61E-68 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS02100 0dd5827c245e56416aa6173a444bdf2c 216 Gene3D G3DSA:2.60.120.590 11 216 2.1E-52 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like WM46_RS02100 0dd5827c245e56416aa6173a444bdf2c 216 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 29 210 2.8E-53 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like WM46_RS02100 0dd5827c245e56416aa6173a444bdf2c 216 SUPERFAMILY SSF51197 15 212 1.79E-61 T 28-03-2018 WM46_RS01525 d21afc130c68121e6bd94f1a3b09ab7a 91 Pfam PF08891 YfcL protein 4 87 6.2E-35 T 28-03-2018 IPR014987 Uncharacterised protein family YfcL WM46_RS01525 d21afc130c68121e6bd94f1a3b09ab7a 91 Gene3D G3DSA:1.10.357.10 2 90 1.6E-4 T 28-03-2018 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 Gene3D G3DSA:2.60.40.10 28 153 5.3E-39 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 Gene3D G3DSA:2.60.40.10 154 240 6.3E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 PRINTS PR00969 Pili chaperone signature 107 124 4.4E-29 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 PRINTS PR00969 Pili chaperone signature 134 149 4.4E-29 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 PRINTS PR00969 Pili chaperone signature 78 99 4.4E-29 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 PRINTS PR00969 Pili chaperone signature 169 184 4.4E-29 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 PRINTS PR00969 Pili chaperone signature 29 38 4.4E-29 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 106 123 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 29 152 6.1E-45 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 SUPERFAMILY SSF49584 146 236 2.35E-16 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 SUPERFAMILY SSF49354 26 152 3.76E-42 T 28-03-2018 IPR008962 PapD-like WM46_RS06010 15be2a41ebe2f9a37f699f870263276d 240 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 175 233 2.1E-10 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS23510 a22cd2bd8a612a706bf8447f75b0f541 256 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 21 243 7.6E-55 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 WM46_RS23510 a22cd2bd8a612a706bf8447f75b0f541 256 Gene3D G3DSA:3.20.20.60 4 248 1.1E-45 T 28-03-2018 WM46_RS23510 a22cd2bd8a612a706bf8447f75b0f541 256 SUPERFAMILY SSF51621 3 255 2.09E-79 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 SUPERFAMILY SSF101801 54 135 4.32E-27 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 56 126 3.5E-26 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 53 128 8.6E-34 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 102 117 1.8E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 56 72 1.8E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 73 89 1.8E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 PRINTS PR00956 Flagellar motor switch protein FliN signature 89 102 1.8E-30 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 Gene3D G3DSA:2.30.330.10 43 137 8.4E-31 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) WM46_RS03795 28b586bf1d6e110d2eaed6efa6ca79bf 137 Pfam PF16973 Flagellar motor switch protein FliN N-terminal 1 49 7.6E-20 T 28-03-2018 IPR031576 Flagellar motor switch protein FliN, N-terminal WM46_RS12965 d7b263b72425ea85b46a65b32a86a82d 152 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 33.01 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 WM46_RS12965 d7b263b72425ea85b46a65b32a86a82d 152 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 143 3.4E-49 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 Gene3D G3DSA:2.30.40.10 326 384 4.1E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 Pfam PF01979 Amidohydrolase family 266 374 5.7E-8 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 Gene3D G3DSA:3.20.20.140 76 325 2.8E-116 T 28-03-2018 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 TIGRFAM TIGR01975 isoAsp_dipep: beta-aspartyl peptidase 9 388 2.2E-169 T 28-03-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 PIRSF PIRSF001238 8 388 3.4E-154 T 28-03-2018 IPR010229 Peptidase M38, beta-aspartyl dipeptidase GO:0008798 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 Gene3D G3DSA:2.30.40.10 9 75 5.4E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 SUPERFAMILY SSF51556 63 346 6.35E-71 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 SUPERFAMILY SSF51338 8 62 2.27E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24490 c68da720d1b978deb75ae9d7890c2df4 388 SUPERFAMILY SSF51338 346 386 2.27E-23 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24535 227d84e11dc1da7272a8fcea4a7710b7 337 Pfam PF00419 Fimbrial protein 195 337 3.7E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24535 227d84e11dc1da7272a8fcea4a7710b7 337 Gene3D G3DSA:2.60.40.1090 190 337 2.0E-28 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24535 227d84e11dc1da7272a8fcea4a7710b7 337 SUPERFAMILY SSF49401 202 337 1.64E-26 T 28-03-2018 IPR008966 Adhesion domain WM46_RS21910 547a827c49c975723dfe6b8ae569170d 784 SUPERFAMILY SSF52540 215 358 3.24E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21910 547a827c49c975723dfe6b8ae569170d 784 SUPERFAMILY SSF52540 66 138 3.24E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21910 547a827c49c975723dfe6b8ae569170d 784 Pfam PF00350 Dynamin family 80 289 2.0E-18 T 28-03-2018 IPR022812 Dynamin superfamily WM46_RS21910 547a827c49c975723dfe6b8ae569170d 784 Gene3D G3DSA:3.40.50.300 59 608 4.2E-31 T 28-03-2018 WM46_RS04865 8bbe959253d561505bf7d3e231d4384e 427 Pfam PF04403 Paraquat-inducible protein A 67 217 9.3E-38 T 28-03-2018 IPR007498 Paraquat-inducible protein A WM46_RS04865 8bbe959253d561505bf7d3e231d4384e 427 Pfam PF04403 Paraquat-inducible protein A 263 418 1.2E-43 T 28-03-2018 IPR007498 Paraquat-inducible protein A WM46_RS04865 8bbe959253d561505bf7d3e231d4384e 427 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 17 417 5.1E-193 T 28-03-2018 IPR005219 Conserved hypothetical protein CHP00155 WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 Gene3D G3DSA:3.40.930.10 3 143 1.4E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 Gene3D G3DSA:3.40.930.10 145 279 2.8E-4 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 297 304 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 287 368 3.6E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 326 341 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 SUPERFAMILY SSF55804 2 140 8.11E-40 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 SUPERFAMILY SSF55804 150 276 2.62E-12 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 Gene3D G3DSA:3.30.1340.10 282 369 6.1E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 PRINTS PR00107 Phosphocarrier protein signature 340 357 2.1E-18 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 PRINTS PR00107 Phosphocarrier protein signature 297 313 2.1E-18 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 PRINTS PR00107 Phosphocarrier protein signature 325 340 2.1E-18 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 139 1.2E-29 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 SUPERFAMILY SSF55594 288 375 1.31E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS02370 68941d7516f44994001a6dd29545d95e 376 Pfam PF00381 PTS HPr component phosphorylation site 288 368 8.4E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like WM46_RS18135 a470949b855f6108f27484314e3edf12 127 Gene3D G3DSA:3.40.630.30 1 127 2.5E-10 T 28-03-2018 WM46_RS18135 a470949b855f6108f27484314e3edf12 127 Pfam PF12568 Acetyltransferase (GNAT) domain 2 125 3.8E-47 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS18135 a470949b855f6108f27484314e3edf12 127 SUPERFAMILY SSF55729 18 120 9.72E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS18135 a470949b855f6108f27484314e3edf12 127 Hamap MF_02018 PanD maturation factor [panM]. 1 126 31.401 T 28-03-2018 IPR032900 PanD regulatory factor PanM GO:0015940|GO:0031638 WM46_RS20705 a6087ffc2305417c52dcdecf11378b80 255 Gene3D G3DSA:3.20.20.450 22 253 1.1E-30 T 28-03-2018 IPR001633 EAL domain WM46_RS20705 a6087ffc2305417c52dcdecf11378b80 255 SMART SM00052 7 247 1.4E-38 T 28-03-2018 IPR001633 EAL domain WM46_RS20705 a6087ffc2305417c52dcdecf11378b80 255 SUPERFAMILY SSF141868 26 250 1.03E-31 T 28-03-2018 IPR001633 EAL domain WM46_RS20705 a6087ffc2305417c52dcdecf11378b80 255 Pfam PF00563 EAL domain 27 242 1.5E-29 T 28-03-2018 IPR001633 EAL domain WM46_RS18125 d178169a4797bf007bed90555827b200 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 5.0E-69 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS18125 d178169a4797bf007bed90555827b200 308 Gene3D G3DSA:1.10.3470.10 4 299 2.2E-50 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 2 809 26.288 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Gene3D G3DSA:3.10.20.310 267 346 8.7E-12 T 28-03-2018 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 24 809 2.8E-287 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Gene3D G3DSA:3.10.20.310 175 266 2.5E-21 T 28-03-2018 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Gene3D G3DSA:3.10.20.310 92 174 4.2E-12 T 28-03-2018 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 PIRSF PIRSF006076 1 809 7.0E-257 T 28-03-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Gene3D G3DSA:3.10.20.310 350 387 0.018 T 28-03-2018 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Pfam PF01103 Surface antigen 448 809 5.5E-101 T 28-03-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Pfam PF07244 Surface antigen variable number repeat 266 344 2.0E-11 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Pfam PF07244 Surface antigen variable number repeat 176 263 2.1E-15 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Pfam PF07244 Surface antigen variable number repeat 92 172 6.9E-11 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Pfam PF07244 Surface antigen variable number repeat 348 421 4.9E-14 T 28-03-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Gene3D G3DSA:2.40.160.50 388 809 1.4E-87 T 28-03-2018 WM46_RS13935 d155933fbd9b266c0489849d2bf4fca0 809 Gene3D G3DSA:3.10.20.310 18 91 1.2E-8 T 28-03-2018 WM46_RS11515 6b87a6df5e9e39aa58ba27e9571464fb 207 SMART SM00903 21 172 1.1E-14 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 WM46_RS11515 6b87a6df5e9e39aa58ba27e9571464fb 207 Pfam PF01613 Flavin reductase like domain 23 169 2.3E-19 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 WM46_RS11515 6b87a6df5e9e39aa58ba27e9571464fb 207 SUPERFAMILY SSF50475 2 187 8.34E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS11515 6b87a6df5e9e39aa58ba27e9571464fb 207 Gene3D G3DSA:2.30.110.10 5 197 4.7E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS03045 115d5a4081836103ad363b4a5bd0f9dd 16 Pfam PF08047 Histidine operon leader peptide 1 16 4.6E-10 T 28-03-2018 IPR012565 Histidine operon leader peptide GO:0000105 WM46_RS00735 a630274424eda841161fefad34bfa593 454 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 11 359 3.3E-140 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS00735 a630274424eda841161fefad34bfa593 454 Gene3D G3DSA:2.40.50.140 6 105 1.2E-10 T 28-03-2018 WM46_RS00735 a630274424eda841161fefad34bfa593 454 Pfam PF02601 Exonuclease VII, large subunit 126 440 3.8E-103 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 WM46_RS00735 a630274424eda841161fefad34bfa593 454 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 7 443 30.531 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 WM46_RS00735 a630274424eda841161fefad34bfa593 454 Pfam PF13742 OB-fold nucleic acid binding domain 10 103 1.2E-32 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 WM46_RS24700 b9f868eb7f62d8c0dd5d1fe9a9d0df8f 446 Pfam PF00419 Fimbrial protein 259 446 2.2E-28 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24700 b9f868eb7f62d8c0dd5d1fe9a9d0df8f 446 PIRSF PIRSF029766 6 446 6.6E-119 T 28-03-2018 IPR011228 Uncharacterised conserved protein UCP029766 WM46_RS24700 b9f868eb7f62d8c0dd5d1fe9a9d0df8f 446 Gene3D G3DSA:2.60.40.1090 264 446 3.6E-20 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24700 b9f868eb7f62d8c0dd5d1fe9a9d0df8f 446 SUPERFAMILY SSF49401 266 446 3.33E-9 T 28-03-2018 IPR008966 Adhesion domain WM46_RS10145 ec2518041e5e842d7fd9416f80432bb8 281 Gene3D G3DSA:1.10.3720.10 11 273 4.8E-42 T 28-03-2018 WM46_RS10145 ec2518041e5e842d7fd9416f80432bb8 281 SUPERFAMILY SSF161098 8 266 5.14E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10145 ec2518041e5e842d7fd9416f80432bb8 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 266 5.9E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 SMART SM00382 375 560 1.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 Pfam PF00664 ABC transporter transmembrane region 25 291 5.6E-49 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 Pfam PF00005 ABC transporter 369 513 1.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 SUPERFAMILY SSF52540 361 582 8.75E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 Gene3D G3DSA:3.40.50.300 338 588 3.2E-62 T 28-03-2018 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 556 8.0E-190 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 SUPERFAMILY SSF90123 11 336 2.62E-54 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS09960 ab5644a979594e2591d02d79db7d6db9 588 Gene3D G3DSA:1.20.1560.10 7 337 1.9E-41 T 28-03-2018 WM46_RS04015 1ee1120c59e5baf62e8e3ca07baa5a43 221 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 183 3.7E-35 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS04015 1ee1120c59e5baf62e8e3ca07baa5a43 221 Gene3D G3DSA:3.10.450.50 135 221 1.4E-14 T 28-03-2018 WM46_RS04015 1ee1120c59e5baf62e8e3ca07baa5a43 221 SUPERFAMILY SSF103642 200 220 5.07E-8 T 28-03-2018 WM46_RS04015 1ee1120c59e5baf62e8e3ca07baa5a43 221 Pfam PF02810 SEC-C motif 203 220 1.3E-10 T 28-03-2018 IPR004027 SEC-C motif WM46_RS04015 1ee1120c59e5baf62e8e3ca07baa5a43 221 SUPERFAMILY SSF101327 14 182 1.06E-22 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS04015 1ee1120c59e5baf62e8e3ca07baa5a43 221 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 10 182 8.5E-50 T 28-03-2018 IPR011978 Uncharacterised protein family UPF0149 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 Pfam PF01256 Carbohydrate kinase 258 496 2.4E-77 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 20 220 2.2E-63 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 234 499 23.434 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 PIRSF PIRSF017184 15 504 1.0E-164 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 438 448 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 233 499 1.5E-91 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 Gene3D G3DSA:3.40.50.10260 2 228 9.2E-65 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 19 220 23.749 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 SUPERFAMILY SSF53613 232 498 4.21E-74 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 Pfam PF03853 YjeF-related protein N-terminus 40 199 1.6E-41 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 Gene3D G3DSA:3.40.1190.20 229 500 3.0E-50 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS22860 bedeab3a3d30b354155d0330276b08f3 515 SUPERFAMILY SSF64153 17 256 5.36E-63 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 WM46_RS03485 9dc8c8ddf1a5b6f6c27908ba2b570482 163 Pfam PF00936 BMC domain 4 80 9.1E-21 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03485 9dc8c8ddf1a5b6f6c27908ba2b570482 163 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 3 66 8.0E-15 T 28-03-2018 WM46_RS03485 9dc8c8ddf1a5b6f6c27908ba2b570482 163 SUPERFAMILY SSF143414 3 89 9.42E-23 T 28-03-2018 WM46_RS03485 9dc8c8ddf1a5b6f6c27908ba2b570482 163 SMART SM00877 3 80 4.7E-26 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS21350 7f3ab671fe8c2a0d61434ecce6cf32af 574 PIRSF PIRSF000719 1 574 6.0E-294 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM46_RS21350 7f3ab671fe8c2a0d61434ecce6cf32af 574 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 9 573 0.0 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM46_RS21350 7f3ab671fe8c2a0d61434ecce6cf32af 574 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 1 570 43.471 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM46_RS21350 7f3ab671fe8c2a0d61434ecce6cf32af 574 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 9 566 5.0E-245 T 28-03-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 Pfam PF01228 Glycine radical 688 791 9.8E-30 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 Pfam PF02901 Pyruvate formate lyase-like 11 671 3.3E-211 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 SUPERFAMILY SSF51998 5 808 2.5E-230 T 28-03-2018 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 PIRSF PIRSF000379 55 810 2.4E-196 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 8 810 0.0 T 28-03-2018 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 Gene3D G3DSA:3.20.70.20 9 810 5.9E-275 T 28-03-2018 WM46_RS10315 2255c3861ae1ec75a6069e52951c1485 810 ProSitePatterns PS00850 Glycine radical domain signature. 781 789 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site WM46_RS17200 81243d7e589b93af8f12d370156ca151 199 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 3 199 22.131 T 28-03-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 WM46_RS17200 81243d7e589b93af8f12d370156ca151 199 Pfam PF01794 Ferric reductase like transmembrane component 48 161 1.8E-14 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain WM46_RS22395 7c750486acf63cd414366b7d283a8663 300 Gene3D G3DSA:3.20.20.370 2 268 1.6E-21 T 28-03-2018 WM46_RS22395 7c750486acf63cd414366b7d283a8663 300 Pfam PF01522 Polysaccharide deacetylase 15 163 6.7E-9 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 WM46_RS22395 7c750486acf63cd414366b7d283a8663 300 Hamap MF_01870 Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD [arnD]. 1 295 62.125 T 28-03-2018 IPR023557 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD, probable GO:0016811 WM46_RS22395 7c750486acf63cd414366b7d283a8663 300 SUPERFAMILY SSF88713 2 38 4.17E-23 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS22395 7c750486acf63cd414366b7d283a8663 300 SUPERFAMILY SSF88713 82 280 4.17E-23 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 SUPERFAMILY SSF53850 1 257 1.6E-65 T 28-03-2018 WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 Gene3D G3DSA:3.40.190.10 153 259 4.8E-15 T 28-03-2018 WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 254 4.7E-63 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 SMART SM00062 27 256 5.6E-71 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 253 8.9E-102 T 28-03-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0006810|GO:0030288 WM46_RS01620 7db0a8d3f777c74c27ace9e57eefc819 260 Gene3D G3DSA:3.40.190.10 14 152 3.1E-35 T 28-03-2018 WM46_RS07695 247923d1f83a3eb2f8c4e0aa1a57073c 536 Pfam PF13454 FAD-NAD(P)-binding 5 164 4.1E-29 T 28-03-2018 WM46_RS07695 247923d1f83a3eb2f8c4e0aa1a57073c 536 SUPERFAMILY SSF51905 1 213 7.77E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS07695 247923d1f83a3eb2f8c4e0aa1a57073c 536 Gene3D G3DSA:3.50.50.60 1 175 5.0E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS07695 247923d1f83a3eb2f8c4e0aa1a57073c 536 Gene3D G3DSA:3.40.50.720 182 454 0.13 T 28-03-2018 WM46_RS16550 78b5dafa52769677a45103afbd3b8395 419 SUPERFAMILY SSF53850 29 417 6.52E-72 T 28-03-2018 WM46_RS16550 78b5dafa52769677a45103afbd3b8395 419 Pfam PF01547 Bacterial extracellular solute-binding protein 51 333 3.0E-41 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 WM46_RS16550 78b5dafa52769677a45103afbd3b8395 419 Gene3D G3DSA:3.40.190.10 28 206 5.9E-40 T 28-03-2018 WM46_RS16550 78b5dafa52769677a45103afbd3b8395 419 Gene3D G3DSA:3.40.190.10 207 371 1.2E-14 T 28-03-2018 WM46_RS18480 825421c7e6f298de87f6b1816ca16dc0 346 Pfam PF03747 ADP-ribosylglycohydrolase 10 323 3.3E-52 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 WM46_RS18480 825421c7e6f298de87f6b1816ca16dc0 346 SUPERFAMILY SSF101478 5 344 1.07E-61 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 WM46_RS18480 825421c7e6f298de87f6b1816ca16dc0 346 Gene3D G3DSA:1.10.4080.10 3 344 3.0E-62 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 Pfam PF01230 HIT domain 12 109 4.2E-30 T 28-03-2018 IPR001310 Histidine triad (HIT) protein WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 PRINTS PR00332 Histidine triad family signature 6 22 6.1E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 PRINTS PR00332 Histidine triad family signature 95 105 6.1E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 PRINTS PR00332 Histidine triad family signature 27 45 6.1E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 Gene3D G3DSA:3.30.428.10 2 113 1.2E-29 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 SUPERFAMILY SSF54197 3 113 1.39E-35 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS08630 d692c6b00eec19da0d107cbeeee61852 120 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 28-03-2018 IPR019808 Histidine triad, conserved site WM46_RS02970 69f06fc239d4a11a4a7aaf07a12cf8a7 347 SUPERFAMILY SSF53756 3 344 1.15E-47 T 28-03-2018 WM46_RS02970 69f06fc239d4a11a4a7aaf07a12cf8a7 347 Pfam PF00534 Glycosyl transferases group 1 165 313 7.4E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS02970 69f06fc239d4a11a4a7aaf07a12cf8a7 347 Gene3D G3DSA:3.40.50.2000 138 330 6.3E-30 T 28-03-2018 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 Gene3D G3DSA:1.20.58.340 249 316 1.3E-20 T 28-03-2018 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 SUPERFAMILY SSF144083 251 314 1.57E-20 T 28-03-2018 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 SUPERFAMILY SSF143865 1 255 4.45E-38 T 28-03-2018 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 3 316 7.8E-114 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 Gene3D G3DSA:3.30.460.20 1 124 5.0E-10 T 28-03-2018 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 Pfam PF01544 CorA-like Mg2+ transporter protein 26 312 3.3E-56 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 WM46_RS19090 a3ac43fa0a4b5bc6a77f86fbd70ff6e4 316 Gene3D G3DSA:1.20.58.340 131 248 2.4E-9 T 28-03-2018 WM46_RS21060 b486acc2296caaab05ee8a62974c74a3 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 58 3.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS21060 b486acc2296caaab05ee8a62974c74a3 215 Gene3D G3DSA:1.10.10.60 4 37 1.2E-13 T 28-03-2018 WM46_RS21060 b486acc2296caaab05ee8a62974c74a3 215 Gene3D G3DSA:1.10.260.40 38 137 4.5E-11 T 28-03-2018 WM46_RS21060 b486acc2296caaab05ee8a62974c74a3 215 SUPERFAMILY SSF46689 2 77 8.98E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS21060 b486acc2296caaab05ee8a62974c74a3 215 Hamap MF_01190 HTH-type transcriptional repressor FabR [fabR]. 1 209 52.293 T 28-03-2018 IPR023764 Transcriptional repressor HTH, FabR WM46_RS09150 25ee52f235699a5fe08ee64f4d82a3c0 198 Pfam PF03358 NADPH-dependent FMN reductase 13 143 1.6E-13 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 WM46_RS09150 25ee52f235699a5fe08ee64f4d82a3c0 198 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 198 40.964 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 WM46_RS09150 25ee52f235699a5fe08ee64f4d82a3c0 198 Gene3D G3DSA:3.40.50.360 2 198 1.0E-50 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS09150 25ee52f235699a5fe08ee64f4d82a3c0 198 SUPERFAMILY SSF52218 1 197 2.62E-62 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS09150 25ee52f235699a5fe08ee64f4d82a3c0 198 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 196 5.7E-103 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 WM46_RS00360 4379cd4638333010d901ee60f8050a8c 245 Pfam PF05175 Methyltransferase small domain 46 130 6.6E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 WM46_RS00360 4379cd4638333010d901ee60f8050a8c 245 SUPERFAMILY SSF53335 15 171 7.6E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS00360 4379cd4638333010d901ee60f8050a8c 245 Gene3D G3DSA:3.40.50.150 8 241 2.6E-28 T 28-03-2018 WM46_RS00360 4379cd4638333010d901ee60f8050a8c 245 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 11 245 54.613 T 28-03-2018 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 WM46_RS00360 4379cd4638333010d901ee60f8050a8c 245 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 119 125 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 SUPERFAMILY SSF140490 334 429 1.31E-31 T 28-03-2018 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 349 360 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 421 2.9E-26 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 SUPERFAMILY SSF142984 248 330 1.44E-20 T 28-03-2018 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 SUPERFAMILY SSF142019 16 246 1.22E-85 T 28-03-2018 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 Pfam PF10531 SLBB domain 253 295 1.5E-6 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 226 1.2E-49 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 SMART SM00928 336 381 2.0E-21 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 13 423 1.8E-203 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01780 3e12ce222bd861d5a0455c04fbe58528 445 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 174 189 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS04605 70232b488182684d68c02f44223ac58d 149 SUPERFAMILY SSF103370 1 144 1.27E-47 T 28-03-2018 IPR008711 Recombinase NinB WM46_RS04605 70232b488182684d68c02f44223ac58d 149 Pfam PF05772 NinB protein 1 131 1.0E-52 T 28-03-2018 IPR008711 Recombinase NinB WM46_RS04605 70232b488182684d68c02f44223ac58d 149 Gene3D G3DSA:1.10.3790.10 1 149 1.3E-40 T 28-03-2018 IPR008711 Recombinase NinB WM46_RS04530 461302bfc4fe53f009f36e83dddd1332 94 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 11 70 1.5E-11 T 28-03-2018 IPR012933 HicA mRNA interferase family GO:0003729 WM46_RS04530 461302bfc4fe53f009f36e83dddd1332 94 SUPERFAMILY SSF54786 6 75 2.35E-10 T 28-03-2018 WM46_RS04530 461302bfc4fe53f009f36e83dddd1332 94 Gene3D G3DSA:3.30.920.30 5 78 5.5E-16 T 28-03-2018 WM46_RS14685 0bb36fa82a5686e0a14037c9954568e4 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 286 38.052 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 WM46_RS14685 0bb36fa82a5686e0a14037c9954568e4 316 Gene3D G3DSA:3.40.50.1220 72 286 7.2E-4 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS14685 0bb36fa82a5686e0a14037c9954568e4 316 Pfam PF02401 LytB protein 3 282 8.4E-92 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 WM46_RS14685 0bb36fa82a5686e0a14037c9954568e4 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 1.0E-98 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 WM46_RS18630 8e0ba53f93c81f3f652fbe19a270f876 186 SUPERFAMILY SSF52540 11 179 7.33E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18630 8e0ba53f93c81f3f652fbe19a270f876 186 Gene3D G3DSA:3.40.50.300 9 186 5.6E-13 T 28-03-2018 WM46_RS10565 bd75c1a4924908b5e1b06d0fc1cffeac 302 Pfam PF01933 Uncharacterised protein family UPF0052 12 289 7.3E-77 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 WM46_RS10565 bd75c1a4924908b5e1b06d0fc1cffeac 302 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 12 269 5.2E-101 T 28-03-2018 IPR010119 Gluconeogenesis factor WM46_RS10565 bd75c1a4924908b5e1b06d0fc1cffeac 302 Hamap MF_00973 Gluconeogenesis factor. 8 300 32.428 T 28-03-2018 IPR010119 Gluconeogenesis factor WM46_RS10565 bd75c1a4924908b5e1b06d0fc1cffeac 302 Gene3D G3DSA:3.40.50.10680 89 301 9.5E-41 T 28-03-2018 WM46_RS10565 bd75c1a4924908b5e1b06d0fc1cffeac 302 SUPERFAMILY SSF142338 11 295 8.89E-86 T 28-03-2018 WM46_RS00600 0581237115913785de763c1d3b6496f9 347 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 230 241 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS00600 0581237115913785de763c1d3b6496f9 347 Pfam PF17179 4Fe-4S dicluster domain 229 326 1.2E-30 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS00600 0581237115913785de763c1d3b6496f9 347 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS00600 0581237115913785de763c1d3b6496f9 347 SUPERFAMILY SSF46548 210 341 1.46E-14 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 WM46_RS00600 0581237115913785de763c1d3b6496f9 347 TIGRFAM TIGR02910 sulfite_red_A: sulfite reductase, subunit A 1 342 1.3E-166 T 28-03-2018 IPR014259 Sulphite reductase, subunit A WM46_RS00600 0581237115913785de763c1d3b6496f9 347 Gene3D G3DSA:1.10.1060.10 202 347 1.3E-13 T 28-03-2018 WM46_RS05085 c8af8c28a04962114de35c7d73db0be3 209 Pfam PF13309 HTH domain 145 205 7.1E-17 T 28-03-2018 WM46_RS05085 c8af8c28a04962114de35c7d73db0be3 209 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 9 130 3.0E-55 T 28-03-2018 IPR013559 YheO-like WM46_RS05085 c8af8c28a04962114de35c7d73db0be3 209 Gene3D G3DSA:1.10.10.60 143 208 5.8E-6 T 28-03-2018 WM46_RS05085 c8af8c28a04962114de35c7d73db0be3 209 Pfam PF08348 YheO-like PAS domain 10 120 1.0E-33 T 28-03-2018 IPR013559 YheO-like WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 23 469 2.2E-199 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 Gene3D G3DSA:3.20.20.70 7 497 4.5E-115 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 SUPERFAMILY SSF54631 109 218 7.2E-24 T 28-03-2018 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 SMART SM00116 173 221 5.5E-7 T 28-03-2018 IPR000644 CBS domain WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 SMART SM00116 111 159 2.7E-11 T 28-03-2018 IPR000644 CBS domain WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 310 322 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 PIRSF PIRSF000130 15 503 9.0E-197 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 23 488 1.1E-161 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 Pfam PF00571 CBS domain 168 217 0.0014 T 28-03-2018 IPR000644 CBS domain WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 Pfam PF00571 CBS domain 110 155 1.7E-8 T 28-03-2018 IPR000644 CBS domain WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 23 501 84.692 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 SUPERFAMILY SSF51412 232 492 1.57E-127 T 28-03-2018 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 SUPERFAMILY SSF51412 16 105 1.57E-127 T 28-03-2018 WM46_RS00740 467fe348ce9ad931245c4eb83722b3e7 503 SMART SM01240 22 488 0.0 T 28-03-2018 WM46_RS02235 12d8dbc1ea5dd635e6724b22f19a3e1f 75 PIRSF PIRSF006188 1 72 1.2E-38 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 WM46_RS02235 12d8dbc1ea5dd635e6724b22f19a3e1f 75 Hamap MF_00816 UPF0352 protein YejL [yejL]. 1 71 24.51 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 WM46_RS02235 12d8dbc1ea5dd635e6724b22f19a3e1f 75 SUPERFAMILY SSF158651 1 75 2.35E-32 T 28-03-2018 IPR023202 YejL-like domain WM46_RS02235 12d8dbc1ea5dd635e6724b22f19a3e1f 75 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 7.0E-32 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 WM46_RS02235 12d8dbc1ea5dd635e6724b22f19a3e1f 75 Pfam PF07208 Protein of unknown function (DUF1414) 26 69 1.3E-24 T 28-03-2018 IPR009857 Uncharacterised protein family UPF0352 WM46_RS02235 12d8dbc1ea5dd635e6724b22f19a3e1f 75 Gene3D G3DSA:1.10.3390.10 2 71 8.0E-36 T 28-03-2018 IPR023202 YejL-like domain WM46_RS19800 ba4dd96843e18a4b651e19b475450cf1 32 Pfam PF08049 IlvB leader peptide 1 32 2.0E-15 T 28-03-2018 IPR012566 IlvB leader peptide WM46_RS12555 a09e94e3302dc99b4ca16d7513213b64 428 TIGRFAM TIGR00836 amt: ammonium transporter 31 426 2.7E-138 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 WM46_RS12555 a09e94e3302dc99b4ca16d7513213b64 428 Gene3D G3DSA:1.10.3430.10 23 407 9.8E-133 T 28-03-2018 WM46_RS12555 a09e94e3302dc99b4ca16d7513213b64 428 ProSitePatterns PS01219 Ammonium transporters signature. 182 207 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 WM46_RS12555 a09e94e3302dc99b4ca16d7513213b64 428 SUPERFAMILY SSF111352 27 407 3.79E-128 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 WM46_RS12555 a09e94e3302dc99b4ca16d7513213b64 428 Pfam PF00909 Ammonium Transporter Family 33 426 1.7E-129 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 WM46_RS02770 83b041bf2c5c791901d64147aeb27b35 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 190 4.4E-66 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 WM46_RS02770 83b041bf2c5c791901d64147aeb27b35 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 190 33.623 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 WM46_RS02770 83b041bf2c5c791901d64147aeb27b35 193 Gene3D G3DSA:2.70.40.10 2 167 1.8E-42 T 28-03-2018 WM46_RS02770 83b041bf2c5c791901d64147aeb27b35 193 SUPERFAMILY SSF51283 1 193 8.64E-59 T 28-03-2018 IPR029054 dUTPase-like WM46_RS02770 83b041bf2c5c791901d64147aeb27b35 193 Pfam PF00692 dUTPase 78 185 1.0E-8 T 28-03-2018 IPR029054 dUTPase-like WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 Gene3D G3DSA:1.10.10.10 3 61 4.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 97 108 - T 28-03-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 SUPERFAMILY SSF46785 7 65 2.66E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 SMART SM01134 74 235 1.6E-72 T 28-03-2018 WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 Pfam PF00455 DeoR C terminal sensor domain 76 234 1.5E-52 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 Gene3D G3DSA:3.40.50.1360 74 241 1.9E-41 T 28-03-2018 WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 SUPERFAMILY SSF100950 75 235 3.18E-34 T 28-03-2018 WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 SMART SM00420 7 59 2.3E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS16580 32e6cfa009ead73e1b4b35255581a462 256 Pfam PF08220 DeoR-like helix-turn-helix domain 7 61 1.9E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 WM46_RS05115 77694027349316cfe259be1c55852ae5 266 Gene3D G3DSA:3.30.460.10 4 125 9.3E-14 T 28-03-2018 WM46_RS05115 77694027349316cfe259be1c55852ae5 266 Pfam PF13427 Domain of unknown function (DUF4111) 153 255 2.7E-27 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 WM46_RS05115 77694027349316cfe259be1c55852ae5 266 Pfam PF01909 Nucleotidyltransferase domain 25 59 1.6E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 WM46_RS05115 77694027349316cfe259be1c55852ae5 266 PIRSF PIRSF000819 8 262 5.7E-55 T 28-03-2018 IPR024172 Streptomycin 3''-adenylyltransferase GO:0009012|GO:0046677 WM46_RS05115 77694027349316cfe259be1c55852ae5 266 SUPERFAMILY SSF81301 5 89 1.69E-13 T 28-03-2018 WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 Pfam PF01228 Glycine radical 634 745 1.9E-41 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 15 764 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 ProSitePatterns PS00850 Glycine radical domain signature. 734 742 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 Gene3D G3DSA:3.20.70.20 6 764 2.5E-280 T 28-03-2018 WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 Pfam PF02901 Pyruvate formate lyase-like 26 618 3.4E-194 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 SUPERFAMILY SSF51998 8 763 2.29E-281 T 28-03-2018 WM46_RS16485 84fec8aa124a4cbcb49f940622576580 764 PIRSF PIRSF000379 12 764 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS15470 362ceb4b6988227bfd148bca8d56d2d6 110 Gene3D G3DSA:3.30.450.20 16 108 5.0E-49 T 28-03-2018 WM46_RS15470 362ceb4b6988227bfd148bca8d56d2d6 110 SUPERFAMILY SSF143737 3 107 2.22E-52 T 28-03-2018 WM46_RS15470 362ceb4b6988227bfd148bca8d56d2d6 110 Pfam PF06154 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A 7 106 5.3E-49 T 28-03-2018 IPR009320 Antitoxin CbeA GO:0051495 WM46_RS09735 260e3fbd30e138f2bd9afb32b8a0e09d 255 SMART SM00382 36 210 7.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09735 260e3fbd30e138f2bd9afb32b8a0e09d 255 SUPERFAMILY SSF52540 14 217 3.15E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09735 260e3fbd30e138f2bd9afb32b8a0e09d 255 Pfam PF00005 ABC transporter 27 160 3.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09735 260e3fbd30e138f2bd9afb32b8a0e09d 255 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09735 260e3fbd30e138f2bd9afb32b8a0e09d 255 Gene3D G3DSA:3.40.50.300 11 220 5.6E-57 T 28-03-2018 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 2 359 1.1E-169 T 28-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 355 6.1E-87 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 Gene3D G3DSA:3.40.718.10 1 212 5.7E-65 T 28-03-2018 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 Gene3D G3DSA:3.40.718.10 213 360 1.6E-56 T 28-03-2018 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 SMART SM01329 6 355 6.9E-181 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 WM46_RS05030 2e4783c10d804fce487e3e84881eb87e 361 SUPERFAMILY SSF53659 2 359 8.06E-117 T 28-03-2018 WM46_RS24625 de30daced583a5a45518dc254e03c34b 198 SUPERFAMILY SSF56349 3 184 5.59E-41 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS24625 de30daced583a5a45518dc254e03c34b 198 Pfam PF00589 Phage integrase family 6 176 1.5E-46 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS24625 de30daced583a5a45518dc254e03c34b 198 Gene3D G3DSA:1.10.443.10 2 177 5.3E-36 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS05950 eb31f44b77566ba0ec9da3761a321165 72 ProDom PD052686 LIPOPROTEIN INDUCIBLE OSMOTICALLY B PRECURSOR SIGNAL MEMBRANE PALMITATE TRANSMEMBRANE SURFACE 12 50 1.0E-6 T 28-03-2018 WM46_RS05950 eb31f44b77566ba0ec9da3761a321165 72 Pfam PF05433 Glycine zipper 2TM domain 34 71 1.7E-7 T 28-03-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 WM46_RS21240 537bb11a4a998141589dd974771298a2 633 Pfam PF13667 ThiC-associated domain 29 110 2.6E-32 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 WM46_RS21240 537bb11a4a998141589dd974771298a2 633 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 149 601 1.5E-224 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 WM46_RS21240 537bb11a4a998141589dd974771298a2 633 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 149 603 56.197 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 WM46_RS21240 537bb11a4a998141589dd974771298a2 633 Pfam PF01964 Radical SAM ThiC family 150 598 4.5E-199 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 WM46_RS16915 f56be7d7400b73e84d2a752fbb913c6e 188 Gene3D G3DSA:3.40.50.1000 3 188 1.4E-25 T 28-03-2018 IPR023214 HAD-like domain WM46_RS16915 f56be7d7400b73e84d2a752fbb913c6e 188 Pfam PF08282 haloacid dehalogenase-like hydrolase 94 158 6.1E-10 T 28-03-2018 IPR023214 HAD-like domain WM46_RS16915 f56be7d7400b73e84d2a752fbb913c6e 188 SUPERFAMILY SSF56784 22 181 2.84E-40 T 28-03-2018 IPR023214 HAD-like domain WM46_RS16915 f56be7d7400b73e84d2a752fbb913c6e 188 PIRSF PIRSF006118 13 188 2.1E-73 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS16915 f56be7d7400b73e84d2a752fbb913c6e 188 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 26 178 4.4E-75 T 28-03-2018 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS21510 9b253dbdc5ceb071ba1ced1ae5f9d0d8 212 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 13 206 2.3E-62 T 28-03-2018 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB WM46_RS21510 9b253dbdc5ceb071ba1ced1ae5f9d0d8 212 SUPERFAMILY SSF159270 20 209 1.22E-56 T 28-03-2018 IPR023373 YmcC-like domain WM46_RS21510 9b253dbdc5ceb071ba1ced1ae5f9d0d8 212 Gene3D G3DSA:2.40.360.10 17 212 1.4E-60 T 28-03-2018 IPR023373 YmcC-like domain WM46_RS04625 41b02c96ec150974a4205c5eae2b74c9 265 SUPERFAMILY SSF57938 167 217 6.54E-7 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 WM46_RS04625 41b02c96ec150974a4205c5eae2b74c9 265 Pfam PF03589 Antitermination protein 23 109 8.5E-22 T 28-03-2018 IPR003222 Antitermination protein GO:0003677|GO:0006355 WM46_RS04625 41b02c96ec150974a4205c5eae2b74c9 265 Pfam PF03589 Antitermination protein 176 257 1.0E-20 T 28-03-2018 IPR003222 Antitermination protein GO:0003677|GO:0006355 WM46_RS04625 41b02c96ec150974a4205c5eae2b74c9 265 Gene3D G3DSA:2.10.230.10 103 188 7.8E-10 T 28-03-2018 WM46_RS13885 6660a46b026b66526c82dac33e495426 129 Gene3D G3DSA:3.10.180.10 1 129 6.1E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS13885 6660a46b026b66526c82dac33e495426 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 126 9.5E-22 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM46_RS13885 6660a46b026b66526c82dac33e495426 129 SUPERFAMILY SSF54593 3 128 1.32E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 Pfam PF07702 UTRA domain 93 229 1.2E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 SMART SM00345 10 69 4.3E-26 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 1.7E-24 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 Gene3D G3DSA:1.10.10.10 1 71 3.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 SUPERFAMILY SSF46785 2 73 2.73E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 SMART SM00866 90 229 3.0E-30 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 SUPERFAMILY SSF64288 58 236 3.93E-43 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS10860 5851538b33a005fa68a6680bbfd2554d 239 Gene3D G3DSA:3.40.1410.10 72 239 9.6E-36 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS04725 34ed77879ae9577b0db0ee1f8f8b9ee8 226 Gene3D G3DSA:2.40.30.20 17 99 1.8E-4 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 WM46_RS04725 34ed77879ae9577b0db0ee1f8f8b9ee8 226 Pfam PF08813 Phage tail tube protein, TTP 51 215 1.7E-50 T 28-03-2018 IPR014918 Phage tail tube protein 3 WM46_RS09585 721eda688c14cee35f8f83cd30c55ceb 109 Pfam PF04358 DsrC like protein 4 109 3.4E-45 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE WM46_RS09585 721eda688c14cee35f8f83cd30c55ceb 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 109 1.3E-49 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE WM46_RS09585 721eda688c14cee35f8f83cd30c55ceb 109 Gene3D G3DSA:1.10.10.370 40 108 1.2E-33 T 28-03-2018 WM46_RS09585 721eda688c14cee35f8f83cd30c55ceb 109 PIRSF PIRSF006223 2 109 6.1E-46 T 28-03-2018 IPR007453 Sulphur transfer protein DsrC/TusE WM46_RS09585 721eda688c14cee35f8f83cd30c55ceb 109 SUPERFAMILY SSF69721 2 109 2.22E-41 T 28-03-2018 IPR025526 DsrC-like domain WM46_RS09585 721eda688c14cee35f8f83cd30c55ceb 109 Gene3D G3DSA:3.30.1420.10 2 39 6.4E-15 T 28-03-2018 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 SMART SM00448 2 113 3.2E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 188 6.4E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 178 5.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 136 150 5.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 166 5.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 Gene3D G3DSA:1.10.10.10 128 189 6.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 150 177 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 Gene3D G3DSA:3.40.50.2300 2 127 1.8E-23 T 28-03-2018 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 Pfam PF00072 Response regulator receiver domain 4 113 3.1E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 SMART SM00421 133 190 6.9E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS07765 add73e91548066f2142d3dc6d63ef2e4 200 SUPERFAMILY SSF52172 6 155 1.21E-28 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS07455 63fa88ca4ebd554011cf797599e0586b 206 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 191 6.5E-68 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 WM46_RS07455 63fa88ca4ebd554011cf797599e0586b 206 PIRSF PIRSF006091 1 201 1.1E-69 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 WM46_RS07455 63fa88ca4ebd554011cf797599e0586b 206 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 2 193 26.497 T 28-03-2018 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 WM46_RS07455 63fa88ca4ebd554011cf797599e0586b 206 Pfam PF04205 FMN-binding domain 99 187 3.0E-19 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 WM46_RS07455 63fa88ca4ebd554011cf797599e0586b 206 SMART SM00900 99 191 3.8E-37 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 WM46_RS07455 63fa88ca4ebd554011cf797599e0586b 206 Gene3D G3DSA:3.40.630.30 23 193 0.001 T 28-03-2018 WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 Pfam PF09383 NIL domain 268 339 1.1E-19 T 28-03-2018 IPR018449 NIL domain WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 343 7.2E-205 T 28-03-2018 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 SMART SM00930 265 340 3.0E-24 T 28-03-2018 IPR018449 NIL domain WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 SUPERFAMILY SSF52540 1 240 9.78E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 SMART SM00382 30 218 2.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 Pfam PF00005 ABC transporter 21 169 1.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 Gene3D G3DSA:3.30.70.260 254 343 1.3E-24 T 28-03-2018 WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 Gene3D G3DSA:3.40.50.300 1 253 9.6E-77 T 28-03-2018 WM46_RS13820 68f6e6d6a0e7f32d16863a9c71e83fcd 343 SUPERFAMILY SSF55021 248 343 1.26E-25 T 28-03-2018 WM46_RS13715 32e5f86e1c8217c0146316a271143a60 255 Gene3D G3DSA:3.60.20.10 1 255 2.4E-45 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS13715 32e5f86e1c8217c0146316a271143a60 255 Pfam PF13230 Glutamine amidotransferases class-II 1 252 2.4E-113 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 WM46_RS13715 32e5f86e1c8217c0146316a271143a60 255 SUPERFAMILY SSF56235 2 253 6.75E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 9 179 30.534 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 15 84 1.7E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 ProSitePatterns PS00938 Initiation factor 3 signature. 66 79 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 SUPERFAMILY SSF54364 13 86 1.05E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 SUPERFAMILY SSF55200 90 179 1.23E-34 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 Gene3D G3DSA:3.30.110.10 87 180 1.9E-35 T 28-03-2018 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 15 179 1.2E-76 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 91 177 3.2E-37 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 WM46_RS08035 2c9c92ce63ad558f700af51d52a7c31f 180 Gene3D G3DSA:3.10.20.80 10 86 6.9E-32 T 28-03-2018 WM46_RS03865 471207efd3c5a5e3d51dbd0e3f35ed6f 122 Pfam PF05400 Flagellar protein FliT 21 105 6.7E-23 T 28-03-2018 IPR008622 Flagellar protein FliT WM46_RS03865 471207efd3c5a5e3d51dbd0e3f35ed6f 122 Gene3D G3DSA:1.20.58.380 6 89 1.0E-22 T 28-03-2018 WM46_RS11040 fde90cb4df9c9bed824dad1442a1c9ec 331 Pfam PF06166 Protein of unknown function (DUF979) 7 330 2.1E-128 T 28-03-2018 IPR009323 Protein of unknown function DUF979 WM46_RS12750 b668f322c5cb8798898f4f70571c2ec7 324 Gene3D G3DSA:3.20.20.100 1 321 3.0E-98 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS12750 b668f322c5cb8798898f4f70571c2ec7 324 SUPERFAMILY SSF51430 1 320 8.64E-101 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS12750 b668f322c5cb8798898f4f70571c2ec7 324 PRINTS PR00069 Aldo-keto reductase signature 142 159 2.8E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS12750 b668f322c5cb8798898f4f70571c2ec7 324 PRINTS PR00069 Aldo-keto reductase signature 230 254 2.8E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS12750 b668f322c5cb8798898f4f70571c2ec7 324 PRINTS PR00069 Aldo-keto reductase signature 111 129 2.8E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS12750 b668f322c5cb8798898f4f70571c2ec7 324 Pfam PF00248 Aldo/keto reductase family 15 312 7.2E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS16130 2a0b17e1bac0c2ea1eaae16ed3647beb 493 Gene3D G3DSA:1.20.1600.10 12 437 1.5E-76 T 28-03-2018 WM46_RS16130 2a0b17e1bac0c2ea1eaae16ed3647beb 493 SUPERFAMILY SSF56954 25 444 3.14E-98 T 28-03-2018 WM46_RS16130 2a0b17e1bac0c2ea1eaae16ed3647beb 493 Pfam PF02321 Outer membrane efflux protein 232 427 4.6E-33 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS16130 2a0b17e1bac0c2ea1eaae16ed3647beb 493 Pfam PF02321 Outer membrane efflux protein 27 209 8.1E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS16130 2a0b17e1bac0c2ea1eaae16ed3647beb 493 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 441 6.0E-142 T 28-03-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 WM46_RS22280 9e8362db8ec7f515f86c636407ba7938 288 Gene3D G3DSA:1.20.120.330 63 198 6.0E-7 T 28-03-2018 WM46_RS02535 7fad4ff93f4c096f96906d8f284149c9 479 Pfam PF02321 Outer membrane efflux protein 294 443 3.9E-11 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS02535 7fad4ff93f4c096f96906d8f284149c9 479 Pfam PF02321 Outer membrane efflux protein 67 265 1.4E-20 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS02535 7fad4ff93f4c096f96906d8f284149c9 479 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 15 475 9.6E-84 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 WM46_RS02535 7fad4ff93f4c096f96906d8f284149c9 479 Gene3D G3DSA:1.20.1600.10 22 479 1.5E-66 T 28-03-2018 WM46_RS02535 7fad4ff93f4c096f96906d8f284149c9 479 SUPERFAMILY SSF56954 3 476 4.05E-77 T 28-03-2018 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 123 145 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 46 67 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 88 112 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 29 45 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 160 189 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 260 286 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PRINTS PR00073 Coprogen oxidase signature 232 259 8.7E-89 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 Gene3D G3DSA:3.40.1500.10 1 299 4.2E-139 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 Pfam PF01218 Coproporphyrinogen III oxidase 7 299 2.4E-132 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 164 188 - T 28-03-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 PIRSF PIRSF000166 2 299 3.3E-128 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 2 275 58.983 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS01035 26269f75009c49bb6f0987c420d8948a 299 SUPERFAMILY SSF102886 3 298 5.23E-139 T 28-03-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 WM46_RS08385 85805b2151d923801ea2a42e912b8246 148 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 148 18.603 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame WM46_RS08385 85805b2151d923801ea2a42e912b8246 148 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 1 130 2.0E-30 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame WM46_RS08385 85805b2151d923801ea2a42e912b8246 148 Pfam PF04284 Protein of unknown function (DUF441) 7 145 1.7E-45 T 28-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame WM46_RS09305 47bc11483023d83b79764355b29fd376 247 SUPERFAMILY SSF52540 15 186 7.11E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09305 47bc11483023d83b79764355b29fd376 247 Gene3D G3DSA:3.40.50.300 14 190 2.1E-14 T 28-03-2018 WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 Gene3D G3DSA:1.20.1250.20 10 215 5.3E-24 T 28-03-2018 WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 SUPERFAMILY SSF103473 270 499 2.79E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 SUPERFAMILY SSF103473 18 219 2.79E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 Pfam PF00854 POT family 91 464 2.3E-63 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 155 167 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 79 103 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 Gene3D G3DSA:1.20.1250.20 285 513 1.4E-16 T 28-03-2018 WM46_RS13215 a8b215567dcf40d4f35185c341d849e9 514 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 11 501 3.9E-109 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 WM46_RS05140 70e9868b84365a6fcdcbecd8db9d3896 219 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 18 210 7.7E-52 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS05140 70e9868b84365a6fcdcbecd8db9d3896 219 SUPERFAMILY SSF56529 11 213 2.22E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS05140 70e9868b84365a6fcdcbecd8db9d3896 219 Gene3D G3DSA:3.90.850.10 2 218 8.5E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13355 966c3967aedeeeb5b35221d898a795c4 126 SUPERFAMILY SSF55331 2 126 7.87E-45 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily WM46_RS13355 966c3967aedeeeb5b35221d898a795c4 126 Gene3D G3DSA:3.30.429.10 1 126 4.8E-46 T 28-03-2018 WM46_RS13355 966c3967aedeeeb5b35221d898a795c4 126 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 124 4.5E-26 T 28-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 1.9E-49 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 SUPERFAMILY SSF53271 69 306 7.85E-67 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 SMART SM01400 4 121 5.7E-76 T 28-03-2018 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 314 1.8E-127 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 313 1.5E-30 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 Gene3D G3DSA:3.40.50.2020 153 307 1.0E-42 T 28-03-2018 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 Gene3D G3DSA:3.40.50.2020 1 152 8.5E-66 T 28-03-2018 WM46_RS05530 9345abfa17bfed25372c2eef21741fe4 315 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 4 314 49.752 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 WM46_RS17640 7006507c173b92b160336c67029c8ca8 184 Hamap MF_01415 Glutathione-regulated potassium-efflux system ancillary protein KefG [kefG]. 2 183 48.399 T 28-03-2018 IPR023947 Glutathione-regulated potassium-efflux system ancillary protein KefG GO:0006813 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 WM46_RS17640 7006507c173b92b160336c67029c8ca8 184 Gene3D G3DSA:3.40.50.360 1 180 3.0E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS17640 7006507c173b92b160336c67029c8ca8 184 SUPERFAMILY SSF52218 6 176 1.07E-46 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS17640 7006507c173b92b160336c67029c8ca8 184 Pfam PF02525 Flavodoxin-like fold 7 172 3.9E-40 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS21010 92b35bb80e4f37966548fb67fb1ef503 230 SMART SM01007 6 197 5.7E-66 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS21010 92b35bb80e4f37966548fb67fb1ef503 230 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 195 6.4E-47 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS21010 92b35bb80e4f37966548fb67fb1ef503 230 TIGRFAM TIGR00760 araD: L-ribulose-5-phosphate 4-epimerase 2 230 2.7E-125 T 28-03-2018 IPR004661 L-ribulose-5-phosphate 4-epimerase GO:0008270|GO:0008742|GO:0019572 KEGG: 00040+5.1.3.4|KEGG: 00053+5.1.3.4|MetaCyc: PWY-6961 WM46_RS21010 92b35bb80e4f37966548fb67fb1ef503 230 SUPERFAMILY SSF53639 3 222 7.46E-69 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS21010 92b35bb80e4f37966548fb67fb1ef503 230 Gene3D G3DSA:3.40.225.10 1 230 2.5E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 SUPERFAMILY SSF141523 101 240 3.4E-28 T 28-03-2018 WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 SMART SM00257 45 91 3.5E-7 T 28-03-2018 IPR018392 LysM domain WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 Pfam PF03734 L,D-transpeptidase catalytic domain 103 240 1.8E-19 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 Gene3D G3DSA:3.10.350.10 43 92 1.4E-8 T 28-03-2018 WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 Gene3D G3DSA:2.40.440.10 97 242 1.8E-29 T 28-03-2018 WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 Pfam PF01476 LysM domain 46 91 2.0E-7 T 28-03-2018 IPR018392 LysM domain WM46_RS08570 f96722815b7f1a8423979e336838be8d 321 SUPERFAMILY SSF54106 47 91 8.24E-5 T 28-03-2018 IPR018392 LysM domain WM46_RS03910 f1b4b6c89ff5eb391c463af6a2449468 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS03910 f1b4b6c89ff5eb391c463af6a2449468 250 SUPERFAMILY SSF52540 4 243 6.75E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03910 f1b4b6c89ff5eb391c463af6a2449468 250 Gene3D G3DSA:3.40.50.300 1 248 2.4E-77 T 28-03-2018 WM46_RS03910 f1b4b6c89ff5eb391c463af6a2449468 250 PIRSF PIRSF039085 1 249 2.9E-111 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS03910 f1b4b6c89ff5eb391c463af6a2449468 250 Pfam PF00005 ABC transporter 19 173 1.6E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS03910 f1b4b6c89ff5eb391c463af6a2449468 250 SMART SM00382 28 221 1.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS03780 709d2545ee44fd718730ca030ea51598 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 4.7E-30 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 WM46_RS03780 709d2545ee44fd718730ca030ea51598 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.0E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 WM46_RS03780 709d2545ee44fd718730ca030ea51598 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.0E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 WM46_RS03780 709d2545ee44fd718730ca030ea51598 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.0E-24 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 WM46_RS03780 709d2545ee44fd718730ca030ea51598 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 88 2.6E-34 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 WM46_RS03780 709d2545ee44fd718730ca030ea51598 89 PIRSF PIRSF004669 1 89 1.7E-33 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 WM46_RS20530 1409457ef5cbd19a95a1a58ba701046f 312 Gene3D G3DSA:3.40.1190.20 5 312 3.9E-64 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS20530 1409457ef5cbd19a95a1a58ba701046f 312 Pfam PF00294 pfkB family carbohydrate kinase 6 306 6.3E-62 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS20530 1409457ef5cbd19a95a1a58ba701046f 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS20530 1409457ef5cbd19a95a1a58ba701046f 312 SUPERFAMILY SSF53613 4 310 1.87E-82 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 SUPERFAMILY SSF53955 51 265 1.38E-81 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 Gene3D G3DSA:3.40.710.10 418 807 4.0E-92 T 28-03-2018 WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 Pfam PF17092 Penicillin-binding protein OB-like domain 324 433 6.2E-30 T 28-03-2018 IPR031376 Penicillin-binding protein, OB-like domain WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 Pfam PF00905 Penicillin binding protein transpeptidase domain 437 613 2.7E-24 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 791 2.9E-173 T 28-03-2018 WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 SUPERFAMILY SSF56601 430 618 2.56E-110 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 SUPERFAMILY SSF56601 680 839 2.56E-110 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 SUPERFAMILY SSF56601 219 241 2.56E-110 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 SUPERFAMILY SSF56601 270 321 2.56E-110 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 Gene3D G3DSA:1.10.3810.10 55 254 1.4E-84 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 Gene3D G3DSA:2.40.50.140 356 417 2.9E-22 T 28-03-2018 WM46_RS17815 913509cda5c3795c1e34dfbdeadad53a 858 Pfam PF00912 Transglycosylase 63 237 7.0E-65 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS11650 c0c6932577aded8526bad8cfacdcc54d 313 SUPERFAMILY SSF53822 26 305 9.09E-76 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS11650 c0c6932577aded8526bad8cfacdcc54d 313 Gene3D G3DSA:3.40.50.2300 144 284 2.7E-35 T 28-03-2018 WM46_RS11650 c0c6932577aded8526bad8cfacdcc54d 313 Gene3D G3DSA:3.40.50.2300 20 143 2.9E-25 T 28-03-2018 WM46_RS11650 c0c6932577aded8526bad8cfacdcc54d 313 Pfam PF13407 Periplasmic binding protein domain 29 283 9.6E-58 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS24930 a06efba3f35b273092c42e73954e4f40 417 SMART SM00646 250 404 3.3E-68 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM46_RS24930 a06efba3f35b273092c42e73954e4f40 417 Gene3D G3DSA:3.40.630.40 187 409 2.8E-57 T 28-03-2018 WM46_RS24930 a06efba3f35b273092c42e73954e4f40 417 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 190 404 4.2E-50 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM46_RS24930 a06efba3f35b273092c42e73954e4f40 417 Pfam PF11741 AMIN domain 39 142 7.5E-28 T 28-03-2018 IPR021731 AMIN domain WM46_RS24930 a06efba3f35b273092c42e73954e4f40 417 SUPERFAMILY SSF53187 188 284 9.42E-53 T 28-03-2018 WM46_RS24930 a06efba3f35b273092c42e73954e4f40 417 SUPERFAMILY SSF53187 331 407 9.42E-53 T 28-03-2018 WM46_RS04875 e918a7e16bf3a71f3bcd87e6bcb1c9a8 228 Hamap MF_00749 RNA chaperone ProQ [proQ]. 3 227 30.542 T 28-03-2018 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 WM46_RS04875 e918a7e16bf3a71f3bcd87e6bcb1c9a8 228 Gene3D G3DSA:1.10.1710.10 1 121 2.1E-41 T 28-03-2018 IPR016103 ProQ/FinO domain WM46_RS04875 e918a7e16bf3a71f3bcd87e6bcb1c9a8 228 Pfam PF04352 ProQ/FINO family 8 115 7.7E-43 T 28-03-2018 IPR016103 ProQ/FinO domain WM46_RS04875 e918a7e16bf3a71f3bcd87e6bcb1c9a8 228 SUPERFAMILY SSF48657 5 119 1.96E-40 T 28-03-2018 IPR016103 ProQ/FinO domain WM46_RS04875 e918a7e16bf3a71f3bcd87e6bcb1c9a8 228 SMART SM00945 5 119 1.9E-60 T 28-03-2018 IPR016103 ProQ/FinO domain WM46_RS04875 e918a7e16bf3a71f3bcd87e6bcb1c9a8 228 Pfam PF17516 ProQ C-terminal domain 178 228 2.5E-24 T 28-03-2018 IPR035236 RNA chaperone ProQ, C-terminal WM46_RS08580 8995384c55eca9b5a76ed712d8bbff2a 211 Gene3D G3DSA:1.10.10.60 9 70 1.4E-19 T 28-03-2018 WM46_RS08580 8995384c55eca9b5a76ed712d8bbff2a 211 Gene3D G3DSA:1.10.357.10 71 204 1.1E-22 T 28-03-2018 WM46_RS08580 8995384c55eca9b5a76ed712d8bbff2a 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 5.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS08580 8995384c55eca9b5a76ed712d8bbff2a 211 SUPERFAMILY SSF46689 11 82 1.8E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS08580 8995384c55eca9b5a76ed712d8bbff2a 211 SUPERFAMILY SSF48498 92 206 2.28E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS04720 07a0974555c048632c0e911010382c59 136 Pfam PF13554 Bacteriophage related domain of unknown function 4 130 2.4E-35 T 28-03-2018 IPR025395 Protein of unknown function DUF4128 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 1.2E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 SMART SM00421 143 200 6.1E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 Gene3D G3DSA:1.10.10.10 126 209 3.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 SMART SM00448 2 115 1.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 6.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 6.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 6.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 Gene3D G3DSA:3.40.50.2300 1 125 3.1E-30 T 28-03-2018 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 Pfam PF00072 Response regulator receiver domain 4 116 4.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 SUPERFAMILY SSF46894 134 206 5.1E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS13095 46833c4c117243234b2b33c9a5f87f12 209 SUPERFAMILY SSF52172 1 118 3.13E-29 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 Gene3D G3DSA:3.30.70.20 198 236 1.6E-19 T 28-03-2018 WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 SUPERFAMILY SSF54862 1 503 9.94E-185 T 28-03-2018 WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 492 0.0 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 Gene3D G3DSA:3.30.70.20 365 466 1.0E-30 T 28-03-2018 WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 Gene3D G3DSA:3.30.70.20 237 364 7.1E-31 T 28-03-2018 WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 Pfam PF13247 4Fe-4S dicluster domain 175 271 2.5E-37 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 Gene3D G3DSA:3.30.70.20 5 197 1.6E-28 T 28-03-2018 WM46_RS05640 d5fe3d2d1bf7995a9dcbb1a62074e9d9 511 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 436 2.6E-30 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 WM46_RS09515 d222bbf62900c243f0491b09e8e4c018 267 Pfam PF02567 Phenazine biosynthesis-like protein 9 255 4.2E-46 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM46_RS09515 d222bbf62900c243f0491b09e8e4c018 267 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 238 9.1E-29 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM46_RS09515 d222bbf62900c243f0491b09e8e4c018 267 SUPERFAMILY SSF54506 3 261 1.06E-72 T 28-03-2018 WM46_RS09515 d222bbf62900c243f0491b09e8e4c018 267 PIRSF PIRSF016184 1 262 3.5E-46 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 WM46_RS09515 d222bbf62900c243f0491b09e8e4c018 267 Gene3D G3DSA:3.10.310.10 1 123 5.4E-26 T 28-03-2018 WM46_RS09515 d222bbf62900c243f0491b09e8e4c018 267 Gene3D G3DSA:3.10.310.10 124 250 1.1E-31 T 28-03-2018 WM46_RS16960 435462c90841683e945e5035683e3098 210 Pfam PF10707 PhoP regulatory network protein YrbL 2 185 1.1E-61 T 28-03-2018 IPR019647 PhoP regulatory network protein YrbL WM46_RS16960 435462c90841683e945e5035683e3098 210 SUPERFAMILY SSF56112 13 152 1.12E-7 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS16960 435462c90841683e945e5035683e3098 210 Gene3D G3DSA:1.10.510.10 3 184 1.8E-5 T 28-03-2018 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 SUPERFAMILY SSF56784 5 186 2.27E-45 T 28-03-2018 IPR023214 HAD-like domain WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 2.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 2.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 2.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 2.6E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 121 183 1.0E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 Gene3D G3DSA:3.40.50.1000 68 187 4.5E-23 T 28-03-2018 IPR023214 HAD-like domain WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 Gene3D G3DSA:1.10.150.240 18 67 5.8E-11 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 183 1.3E-26 T 28-03-2018 IPR023214 HAD-like domain WM46_RS25570 9ea62fd94d38f20aadabfcbac4889732 188 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 5 185 1.4E-63 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PRINTS PR00069 Aldo-keto reductase signature 35 59 6.3E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 6.3E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 6.3E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 6.3E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 6.3E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 SUPERFAMILY SSF51430 2 261 1.19E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PIRSF PIRSF000097 1 114 1.9E-38 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 PIRSF PIRSF000097 111 271 5.3E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 Gene3D G3DSA:3.20.20.100 1 273 5.9E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 Pfam PF00248 Aldo/keto reductase family 199 257 3.3E-7 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS11955 dd8939c278754fc6b086a5bf84178cd7 283 Pfam PF00248 Aldo/keto reductase family 15 189 6.0E-37 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS10325 8377c9c3a4523a3baebfed102dad3a4b 420 SUPERFAMILY SSF51197 4 419 3.66E-154 T 28-03-2018 WM46_RS10325 8377c9c3a4523a3baebfed102dad3a4b 420 Pfam PF07350 Protein of unknown function (DUF1479) 16 419 7.5E-143 T 28-03-2018 IPR010856 Protein of unknown function DUF1479 WM46_RS10325 8377c9c3a4523a3baebfed102dad3a4b 420 Gene3D G3DSA:2.60.120.330 1 420 1.5E-129 T 28-03-2018 IPR027443 Isopenicillin N synthase-like WM46_RS03730 144b61902b554cb786f543881c41aecc 155 Pfam PF03852 DNA mismatch endonuclease Vsr 2 74 1.3E-37 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 WM46_RS03730 144b61902b554cb786f543881c41aecc 155 Gene3D G3DSA:3.40.960.10 21 155 1.1E-32 T 28-03-2018 WM46_RS03730 144b61902b554cb786f543881c41aecc 155 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 118 1.9E-53 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 WM46_RS03730 144b61902b554cb786f543881c41aecc 155 PIRSF PIRSF018267 1 148 1.5E-50 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 WM46_RS03730 144b61902b554cb786f543881c41aecc 155 SUPERFAMILY SSF52980 2 153 3.49E-53 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS06535 696cae79cef8be35fa5bc8b846cc23ab 467 PIRSF PIRSF006446 2 456 9.8E-221 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM46_RS06535 696cae79cef8be35fa5bc8b846cc23ab 467 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 437 8.9E-164 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM46_RS09475 000734e2e014d797d6104c889401f6c1 194 Pfam PF11188 Protein of unknown function (DUF2975) 81 192 2.5E-16 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 Gene3D G3DSA:2.40.170.20 156 612 3.2E-66 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 SUPERFAMILY SSF56935 26 612 6.72E-113 T 28-03-2018 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 33 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 TIGRFAM TIGR01779 TonB-B12: TonB-dependent vitamin B12 receptor 2 612 5.0E-204 T 28-03-2018 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 Pfam PF07715 TonB-dependent Receptor Plug Domain 41 146 4.3E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 Pfam PF00593 TonB dependent receptor 179 611 1.5E-41 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 Gene3D G3DSA:2.170.130.10 19 155 7.1E-34 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 Hamap MF_01531 Vitamin B12 transporter BtuB [btuB]. 2 612 34.75 T 28-03-2018 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 WM46_RS21075 c99e1056b963e21dce81b407ed5ea49f 612 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 595 612 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS10845 6deae5661a45e09c1aca1926cf9abb63 522 PIRSF PIRSF006446 355 522 3.8E-29 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM46_RS10845 6deae5661a45e09c1aca1926cf9abb63 522 PIRSF PIRSF006446 1 328 2.0E-114 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM46_RS10845 6deae5661a45e09c1aca1926cf9abb63 522 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 501 9.1E-174 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 Gene3D G3DSA:3.40.50.720 2 255 2.0E-52 T 28-03-2018 WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 0.0083 T 28-03-2018 WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 Pfam PF00106 short chain dehydrogenase 3 191 9.8E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 SUPERFAMILY SSF51735 3 253 4.65E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 5.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 5.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 5.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS12270 ee41c165ef9055b3a74fd83eebebc6b4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 5.0E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 SUPERFAMILY SSF74653 152 221 6.8E-21 T 28-03-2018 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 PRINTS PR01374 Gram-negative bacterial tonB protein signature 91 101 1.3E-39 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 PRINTS PR01374 Gram-negative bacterial tonB protein signature 175 193 1.3E-39 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 PRINTS PR01374 Gram-negative bacterial tonB protein signature 194 211 1.3E-39 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 PRINTS PR01374 Gram-negative bacterial tonB protein signature 154 175 1.3E-39 T 28-03-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 159 227 3.4E-18 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 Pfam PF16031 TonB N-terminal region 33 155 1.5E-31 T 28-03-2018 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 Gene3D G3DSA:3.30.2420.10 163 238 4.5E-20 T 28-03-2018 WM46_RS05790 7a52b1f9880427d8d7e5bf23b7b13539 238 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 160 231 9.7E-20 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 52 69 7.1E-72 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 75 98 7.1E-72 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 100 118 7.1E-72 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 26 47 7.1E-72 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 155 174 7.1E-72 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 192 215 7.1E-72 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 Pfam PF03379 CcmB protein 2 216 2.4E-91 T 28-03-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 PIRSF PIRSF002764 1 219 2.5E-82 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria WM46_RS02170 567f4b3d8dd65b1661c1fede9d22c92c 219 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 5 215 8.5E-95 T 28-03-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria WM46_RS20800 5c3e9984919757f7cc69deb288ba224a 144 PIRSF PIRSF006276 1 141 4.1E-54 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS20800 5c3e9984919757f7cc69deb288ba224a 144 Pfam PF00582 Universal stress protein family 3 138 2.5E-21 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS20800 5c3e9984919757f7cc69deb288ba224a 144 Gene3D G3DSA:3.40.50.620 2 142 1.4E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS20800 5c3e9984919757f7cc69deb288ba224a 144 SUPERFAMILY SSF52402 3 139 1.59E-32 T 28-03-2018 WM46_RS05655 54b1afbfe0471d8a1fd03e43466d9a47 299 SUPERFAMILY SSF103481 184 282 2.35E-14 T 28-03-2018 WM46_RS05655 54b1afbfe0471d8a1fd03e43466d9a47 299 Pfam PF00892 EamA-like transporter family 150 277 6.6E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS05655 54b1afbfe0471d8a1fd03e43466d9a47 299 Pfam PF00892 EamA-like transporter family 8 136 6.8E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS05655 54b1afbfe0471d8a1fd03e43466d9a47 299 SUPERFAMILY SSF103481 38 139 7.32E-13 T 28-03-2018 WM46_RS03400 3b494ff7e631b47c290c48a66a61cecb 82 Pfam PF06183 DinI-like family 16 80 4.6E-19 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS03400 3b494ff7e631b47c290c48a66a61cecb 82 SUPERFAMILY SSF54857 1 81 2.88E-24 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS03400 3b494ff7e631b47c290c48a66a61cecb 82 Gene3D G3DSA:3.30.910.10 1 80 3.6E-29 T 28-03-2018 IPR010391 DNA damage-inducible protein DinI-like WM46_RS04745 3894ac0cd96ce498f4e10663cbee53de 976 Pfam PF06791 Prophage tail length tape measure protein 195 396 2.7E-56 T 28-03-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal WM46_RS04745 3894ac0cd96ce498f4e10663cbee53de 976 Gene3D G3DSA:1.10.10.10 298 779 0.042 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04745 3894ac0cd96ce498f4e10663cbee53de 976 TIGRFAM TIGR01541 tape_meas_lam_C: phage tail tape measure protein, lambda family 585 918 2.8E-75 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal WM46_RS04745 3894ac0cd96ce498f4e10663cbee53de 976 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 740 815 5.2E-22 T 28-03-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 Gene3D G3DSA:3.40.1160.10 1 310 1.5E-56 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 TIGRFAM TIGR00746 arcC: carbamate kinase 3 309 4.0E-116 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PIRSF PIRSF000723 1 310 7.1E-122 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 Pfam PF00696 Amino acid kinase family 3 282 4.7E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 264 279 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 73 91 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 108 127 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 179 197 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 39 58 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 156 175 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 PRINTS PR01469 Bacterial carbamate kinase signature 209 224 7.8E-65 T 28-03-2018 WM46_RS24345 10ed92de6584f1f05eb73f8018f7f8e5 310 SUPERFAMILY SSF53633 3 308 5.37E-83 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 356 376 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 80 105 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 1.4E-37 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 Gene3D G3DSA:1.10.3860.10 1 407 9.9E-107 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 SUPERFAMILY SSF118215 6 403 1.44E-105 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS10895 5e7476d473d6214fe9b8e20c49f574ff 435 Pfam PF00375 Sodium:dicarboxylate symporter family 6 402 1.6E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 WM46_RS18540 9fbdf297eaa084330e145fa7c3788b7e 327 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 14 327 1.0E-129 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS18540 9fbdf297eaa084330e145fa7c3788b7e 327 Gene3D G3DSA:1.20.1640.10 250 322 2.8E-4 T 28-03-2018 WM46_RS18540 9fbdf297eaa084330e145fa7c3788b7e 327 Pfam PF03812 2-keto-3-deoxygluconate permease 3 312 1.6E-116 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS18540 9fbdf297eaa084330e145fa7c3788b7e 327 Hamap MF_00070 2-keto-3-deoxygluconate permease [kdgT]. 1 318 41.187 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS18540 9fbdf297eaa084330e145fa7c3788b7e 327 TIGRFAM TIGR00793 kdgT: 2-keto-3-deoxygluconate transporter 1 314 1.3E-185 T 28-03-2018 IPR018395 2-keto-3-deoxygluconate permease, subgroup GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS00420 07ae267e50a94e27e4522e0f3f2a2f83 243 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 3.1E-114 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM46_RS00420 07ae267e50a94e27e4522e0f3f2a2f83 243 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 135.329 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM46_RS00420 07ae267e50a94e27e4522e0f3f2a2f83 243 SUPERFAMILY SSF63892 4 241 1.96E-102 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM46_RS00420 07ae267e50a94e27e4522e0f3f2a2f83 243 Gene3D G3DSA:3.20.20.70 4 238 8.1E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS00420 07ae267e50a94e27e4522e0f3f2a2f83 243 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 238 1.8E-106 T 28-03-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 WM46_RS12830 fb94f98869b921bbd490a8d1397ca17e 193 Hamap MF_01950 Acyl carrier protein phosphodiesterase [acpH]. 1 193 54.082 T 28-03-2018 IPR023491 Acyl carrier protein phosphodiesterase, gammaproteobacteria GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 WM46_RS12830 fb94f98869b921bbd490a8d1397ca17e 193 PIRSF PIRSF011489 1 193 1.5E-82 T 28-03-2018 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 WM46_RS12830 fb94f98869b921bbd490a8d1397ca17e 193 Pfam PF04336 Acyl carrier protein phosphodiesterase 81 185 8.2E-29 T 28-03-2018 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 WM46_RS17480 3ffe3b0ab46d35559826dede0770529b 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 3.0E-26 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS17480 3ffe3b0ab46d35559826dede0770529b 101 Gene3D G3DSA:4.10.830.10 1 101 5.4E-33 T 28-03-2018 WM46_RS17480 3ffe3b0ab46d35559826dede0770529b 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17480 3ffe3b0ab46d35559826dede0770529b 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.942 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid WM46_RS17480 3ffe3b0ab46d35559826dede0770529b 101 SUPERFAMILY SSF57716 2 101 1.5E-37 T 28-03-2018 WM46_RS22835 6d4c90e889ba77cedb1e017f34c531e5 181 Pfam PF00929 Exonuclease 9 170 8.9E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS22835 6d4c90e889ba77cedb1e017f34c531e5 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 44.81 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 WM46_RS22835 6d4c90e889ba77cedb1e017f34c531e5 181 SUPERFAMILY SSF53098 3 180 8.07E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS22835 6d4c90e889ba77cedb1e017f34c531e5 181 Gene3D G3DSA:3.30.420.10 2 181 6.8E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS22835 6d4c90e889ba77cedb1e017f34c531e5 181 SMART SM00479 7 180 1.8E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS08605 64945160fa35752532f0f85d82e7a137 180 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 177 4.3E-71 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA WM46_RS08605 64945160fa35752532f0f85d82e7a137 180 Hamap MF_01047 UPF0227 protein YcfP [ycfP]. 1 178 55.717 T 28-03-2018 IPR022987 Uncharacterised protein family UPF0227 WM46_RS08605 64945160fa35752532f0f85d82e7a137 180 SUPERFAMILY SSF53474 2 176 2.4E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 Pfam PF00293 NUDIX domain 132 234 4.7E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 SUPERFAMILY SSF55811 3 96 1.28E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 93 124 8.6E-13 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 SUPERFAMILY SSF55811 79 241 1.82E-40 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 Hamap MF_00297 NADH pyrophosphatase [nudC]. 1 257 47.305 T 28-03-2018 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 ProSitePatterns PS00893 Nudix box signature. 159 180 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS21250 ee98b3b01a2f2d93d3c6c4e42c6fbadf 257 Gene3D G3DSA:3.90.79.10 126 257 3.2E-34 T 28-03-2018 WM46_RS06750 b3df9606aac6f24d45bc7e8e649ab38a 462 TIGRFAM TIGR00886 2A0108: nitrite transporter 34 415 1.0E-101 T 28-03-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 WM46_RS06750 b3df9606aac6f24d45bc7e8e649ab38a 462 Pfam PF07690 Major Facilitator Superfamily 43 373 1.4E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS06750 b3df9606aac6f24d45bc7e8e649ab38a 462 Gene3D G3DSA:1.20.1250.20 17 234 6.3E-15 T 28-03-2018 WM46_RS06750 b3df9606aac6f24d45bc7e8e649ab38a 462 SUPERFAMILY SSF103473 18 460 1.02E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06750 b3df9606aac6f24d45bc7e8e649ab38a 462 Gene3D G3DSA:1.20.1250.20 242 462 5.2E-22 T 28-03-2018 WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 590 1063 4.0E-119 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 SUPERFAMILY SSF103515 753 1063 3.66E-48 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 Pfam PF03212 Pertactin 573 689 4.1E-15 T 28-03-2018 IPR004899 Pertactin, central region WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 Gene3D G3DSA:2.40.128.130 746 1063 1.5E-48 T 28-03-2018 WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 Pfam PF03797 Autotransporter beta-domain 791 1041 9.7E-44 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 SUPERFAMILY SSF51126 293 693 5.02E-44 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 SMART SM00869 788 1052 5.7E-40 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS09510 93976f246919b108cd6f0e8dd4b75300 1063 Gene3D G3DSA:2.160.20.20 223 694 5.9E-62 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Pfam PF00270 DEAD/DEAH box helicase 48 212 6.5E-51 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 SMART SM00487 42 240 3.7E-64 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Pfam PF12343 Cold shock protein DEAD box A 584 638 8.9E-9 T 28-03-2018 IPR021046 Cold-shock protein, DEAD box A, C-terminal GO:0016817 WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Pfam PF00271 Helicase conserved C-terminal domain 249 357 8.2E-29 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 SUPERFAMILY SSF52540 164 371 1.86E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Gene3D G3DSA:3.40.50.300 18 236 1.2E-59 T 28-03-2018 WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 SUPERFAMILY SSF52540 9 226 5.43E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 SMART SM00490 276 357 1.5E-31 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 171 179 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Gene3D G3DSA:3.40.50.300 237 425 2.2E-42 T 28-03-2018 WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 18 577 47.333 T 28-03-2018 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 WM46_RS16735 ca9793f1c747be05bcdc7fa0193d2bb4 642 Pfam PF03880 DbpA RNA binding domain 506 575 2.5E-20 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain WM46_RS21265 8f3182026d606c49c61a5802a0bfeed7 196 Pfam PF04222 Protein of unknown function (DUF416) 5 193 1.0E-82 T 28-03-2018 IPR007338 Protein of unknown function DUF416 WM46_RS21265 8f3182026d606c49c61a5802a0bfeed7 196 Gene3D G3DSA:1.20.1590.10 5 194 7.6E-77 T 28-03-2018 IPR023381 YP001051499.1-like domain WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 Pfam PF00520 Ion transport protein 29 243 6.7E-26 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 Gene3D G3DSA:1.20.120.350 24 156 1.6E-20 T 28-03-2018 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 Gene3D G3DSA:1.10.287.70 157 205 1.8E-11 T 28-03-2018 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 157 180 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 64 87 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 90 110 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 18 46 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 128 154 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 215 241 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 PRINTS PR00169 Potassium channel signature 186 208 1.7E-32 T 28-03-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 SUPERFAMILY SSF81324 29 242 4.84E-46 T 28-03-2018 WM46_RS05770 28ad8842b62ebe2e2224cdd638ea5a96 278 Gene3D G3DSA:1.20.5.110 207 242 2.7E-14 T 28-03-2018 WM46_RS20575 f041e014fc3b8e05fa6c1d5f07b7b86f 563 Pfam PF00884 Sulfatase 250 538 1.7E-48 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS20575 f041e014fc3b8e05fa6c1d5f07b7b86f 563 Gene3D G3DSA:3.40.720.10 242 544 1.1E-20 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS20575 f041e014fc3b8e05fa6c1d5f07b7b86f 563 SUPERFAMILY SSF53649 250 542 8.6E-21 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS20575 f041e014fc3b8e05fa6c1d5f07b7b86f 563 Pfam PF08019 Domain of unknown function (DUF1705) 57 170 4.8E-16 T 28-03-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 52 5.4E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 Pfam PF13377 Periplasmic binding protein-like domain 178 328 2.9E-24 T 28-03-2018 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 Gene3D G3DSA:3.40.50.2300 176 315 1.0E-33 T 28-03-2018 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 SMART SM00354 5 75 1.6E-29 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 Gene3D G3DSA:3.40.50.2300 59 175 2.9E-20 T 28-03-2018 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 SUPERFAMILY SSF53822 63 326 3.53E-55 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 SUPERFAMILY SSF47413 4 63 6.19E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 Gene3D G3DSA:1.10.260.40 6 58 2.7E-14 T 28-03-2018 WM46_RS23440 584af7a460f09353b6853fee2305d8fc 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 WM46_RS20015 e91fe6bb02753898968aa9f60a009390 163 SUPERFAMILY SSF55729 1 160 2.09E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS20015 e91fe6bb02753898968aa9f60a009390 163 Gene3D G3DSA:3.40.630.30 1 163 1.4E-27 T 28-03-2018 WM46_RS20015 e91fe6bb02753898968aa9f60a009390 163 Pfam PF00583 Acetyltransferase (GNAT) family 17 141 3.9E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 Pfam PF00271 Helicase conserved C-terminal domain 206 327 3.8E-10 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 SMART SM00487 2 186 2.1E-19 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 PIRSF PIRSF005496 1 809 0.0 T 28-03-2018 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 SUPERFAMILY SSF52540 12 432 3.97E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 Pfam PF08482 ATP-dependent helicase C-terminal 664 796 5.0E-53 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 Pfam PF04408 Helicase associated domain (HA2) 389 444 1.1E-9 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 Gene3D G3DSA:3.40.50.300 180 349 2.1E-41 T 28-03-2018 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 SMART SM00847 388 476 3.4E-11 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 Gene3D G3DSA:3.40.50.300 3 162 4.5E-23 T 28-03-2018 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 SMART SM00490 226 328 4.4E-13 T 28-03-2018 IPR001650 Helicase, C-terminal WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 808 0.0 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 WM46_RS14075 dfb3821ce59ae73bdf86862446046b64 809 Pfam PF00270 DEAD/DEAH box helicase 19 162 1.2E-9 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 Gene3D G3DSA:3.40.50.1400 1 172 1.0E-45 T 28-03-2018 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 Pfam PF00762 Ferrochelatase 5 316 2.5E-108 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 Gene3D G3DSA:3.40.50.1400 173 300 1.1E-39 T 28-03-2018 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 TIGRFAM TIGR00109 hemH: ferrochelatase 1 318 7.4E-125 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 Hamap MF_00323 Ferrochelatase [hemH]. 4 320 37.906 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 SUPERFAMILY SSF53800 4 317 5.23E-101 T 28-03-2018 WM46_RS12360 814189df368e39fc0b21f9edd30fcb9f 320 ProSitePatterns PS00534 Ferrochelatase signature. 189 207 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 Gene3D G3DSA:2.40.50.100 252 293 6.8E-11 T 28-03-2018 WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 SUPERFAMILY SSF52540 4 243 4.03E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 Pfam PF08402 TOBE domain 281 353 5.3E-12 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 SUPERFAMILY SSF50331 236 364 6.07E-31 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 Pfam PF00005 ABC transporter 20 161 1.9E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 SMART SM00382 28 219 6.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 Gene3D G3DSA:3.40.50.300 1 251 1.8E-69 T 28-03-2018 WM46_RS21560 ca2b1bf9da16417c70341a0142036764 369 Gene3D G3DSA:2.40.50.140 294 346 8.8E-10 T 28-03-2018 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 37 396 1.2E-67 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 SUPERFAMILY SSF51556 53 370 1.59E-63 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 Gene3D G3DSA:3.20.20.140 68 370 1.2E-75 T 28-03-2018 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 Pfam PF01979 Amidohydrolase family 49 390 1.2E-21 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 Gene3D G3DSA:2.30.40.10 6 67 8.9E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 PIRSF PIRSF038994 4 399 9.4E-88 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 SUPERFAMILY SSF51338 370 398 2.88E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS01280 52f5eace86693baa0d5d7cc7a198bbef 403 SUPERFAMILY SSF51338 9 52 2.88E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS17030 1a0e8d663054f65b07948cd53be62b79 212 Gene3D G3DSA:3.40.30.10 1 88 2.7E-24 T 28-03-2018 WM46_RS17030 1a0e8d663054f65b07948cd53be62b79 212 SUPERFAMILY SSF47616 82 208 5.26E-28 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS17030 1a0e8d663054f65b07948cd53be62b79 212 Gene3D G3DSA:1.20.1050.10 89 209 3.4E-18 T 28-03-2018 WM46_RS17030 1a0e8d663054f65b07948cd53be62b79 212 SUPERFAMILY SSF52833 7 90 2.76E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS17030 1a0e8d663054f65b07948cd53be62b79 212 Pfam PF00043 Glutathione S-transferase, C-terminal domain 102 194 1.0E-13 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS17030 1a0e8d663054f65b07948cd53be62b79 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 10 81 5.6E-20 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS15485 bd9669cb95c2822dc9411037a906a923 183 Gene3D G3DSA:1.10.357.10 1 183 5.2E-26 T 28-03-2018 WM46_RS15485 bd9669cb95c2822dc9411037a906a923 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS15485 bd9669cb95c2822dc9411037a906a923 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 9.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS15485 bd9669cb95c2822dc9411037a906a923 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 9.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS15485 bd9669cb95c2822dc9411037a906a923 183 SUPERFAMILY SSF46689 6 81 4.0E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05630 a44adefa3b8ab2b35c1097984e098db8 803 Pfam PF01734 Patatin-like phospholipase 63 141 1.8E-7 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 WM46_RS05630 a44adefa3b8ab2b35c1097984e098db8 803 SUPERFAMILY SSF52151 37 110 7.32E-16 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 WM46_RS05630 a44adefa3b8ab2b35c1097984e098db8 803 Gene3D G3DSA:3.40.1090.10 519 716 7.3E-12 T 28-03-2018 WM46_RS05630 a44adefa3b8ab2b35c1097984e098db8 803 Gene3D G3DSA:3.40.1090.10 22 144 7.1E-16 T 28-03-2018 WM46_RS05630 a44adefa3b8ab2b35c1097984e098db8 803 SUPERFAMILY SSF52151 635 794 2.35E-11 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 WM46_RS03275 60a8a7a71052b9ee8e1c40244a2fd7a7 530 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 20 511 2.4E-69 T 28-03-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 WM46_RS03275 60a8a7a71052b9ee8e1c40244a2fd7a7 530 Pfam PF05136 Phage portal protein, lambda family 22 404 1.8E-109 T 28-03-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 WM46_RS11615 8d356a8536886391986d642eaa378858 264 SMART SM00382 32 242 1.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11615 8d356a8536886391986d642eaa378858 264 Gene3D G3DSA:3.40.50.300 6 244 7.3E-59 T 28-03-2018 WM46_RS11615 8d356a8536886391986d642eaa378858 264 Pfam PF00005 ABC transporter 24 171 2.8E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS11615 8d356a8536886391986d642eaa378858 264 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS11615 8d356a8536886391986d642eaa378858 264 SUPERFAMILY SSF52540 8 233 3.75E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06735 731ef10883ce545615f506c82e6d8d4c 231 Pfam PF02613 Nitrate reductase delta subunit 33 151 1.8E-13 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS06735 731ef10883ce545615f506c82e6d8d4c 231 Gene3D G3DSA:1.10.3480.10 19 218 1.4E-32 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS06735 731ef10883ce545615f506c82e6d8d4c 231 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 9 154 1.2E-36 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 WM46_RS06735 731ef10883ce545615f506c82e6d8d4c 231 SUPERFAMILY SSF89155 2 155 2.22E-28 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 Gene3D G3DSA:3.30.43.10 4 56 4.4E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 283 1.9E-26 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 173 1.7E-51 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 SUPERFAMILY SSF56176 6 173 7.09E-51 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 Gene3D G3DSA:3.30.465.10 57 174 5.3E-32 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 SUPERFAMILY SSF55447 181 283 7.06E-27 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 Gene3D G3DSA:3.30.390.50 177 292 8.4E-28 T 28-03-2018 WM46_RS24380 9d06c906e1e151e063cd9d01216dd5d1 292 SMART SM01092 181 283 5.4E-28 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal WM46_RS15515 7f12e4e08c5013d551a0f603bc4b129b 128 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 25 127 1.3E-38 T 28-03-2018 IPR021356 Integrating conjugative element protein PFL4702 WM46_RS15515 7f12e4e08c5013d551a0f603bc4b129b 128 Pfam PF11190 Protein of unknown function (DUF2976) 40 126 4.5E-34 T 28-03-2018 IPR021356 Integrating conjugative element protein PFL4702 WM46_RS11815 aca419e83a35b31adc47869ae6cfee82 391 Gene3D G3DSA:1.10.287.110 227 369 7.2E-4 T 28-03-2018 IPR001623 DnaJ domain WM46_RS11815 aca419e83a35b31adc47869ae6cfee82 391 SUPERFAMILY SSF46565 219 289 4.19E-5 T 28-03-2018 IPR001623 DnaJ domain WM46_RS11815 aca419e83a35b31adc47869ae6cfee82 391 Gene3D G3DSA:1.20.5.320 15 155 0.1 T 28-03-2018 WM46_RS26020 650163ae7c72d2af97ea2718d80b11b8 273 Pfam PF03524 Conjugal transfer protein 14 246 4.0E-54 T 28-03-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX WM46_RS12080 f69cac5ee5376c9444c9cb15aa873a9c 203 SUPERFAMILY SSF53448 20 177 9.0E-5 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02420 e4671e01985a5891ffc8d55d2829e1d1 489 Pfam PF00324 Amino acid permease 21 475 8.6E-145 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS02420 e4671e01985a5891ffc8d55d2829e1d1 489 PIRSF PIRSF006060 1 483 1.0E-77 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS02420 e4671e01985a5891ffc8d55d2829e1d1 489 ProSitePatterns PS00218 Amino acid permeases signature. 46 77 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 SUPERFAMILY SSF53597 1 159 1.7E-55 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 PIRSF PIRSF000194 1 159 1.3E-57 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 Pfam PF00186 Dihydrofolate reductase 1 158 1.7E-58 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 Gene3D G3DSA:3.40.430.10 1 159 1.5E-52 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 PRINTS PR00070 Dihydrofolate reductase signature 27 35 9.8E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 PRINTS PR00070 Dihydrofolate reductase signature 40 51 9.8E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 PRINTS PR00070 Dihydrofolate reductase signature 90 104 9.8E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS14580 35cfaf158bb0b799310c95102189f253 159 PRINTS PR00070 Dihydrofolate reductase signature 13 23 9.8E-15 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS09680 d3cd4ab4ecec17de2c8bfe6b520e4cd4 417 Pfam PF04403 Paraquat-inducible protein A 253 408 2.2E-53 T 28-03-2018 IPR007498 Paraquat-inducible protein A WM46_RS09680 d3cd4ab4ecec17de2c8bfe6b520e4cd4 417 Pfam PF04403 Paraquat-inducible protein A 49 200 2.0E-39 T 28-03-2018 IPR007498 Paraquat-inducible protein A WM46_RS09680 d3cd4ab4ecec17de2c8bfe6b520e4cd4 417 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 1 408 3.7E-189 T 28-03-2018 IPR005219 Conserved hypothetical protein CHP00155 WM46_RS11785 fc82587aa319c2d67fb5238cb5246df5 380 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 269 2.1E-6 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS11785 fc82587aa319c2d67fb5238cb5246df5 380 Gene3D G3DSA:3.30.360.10 143 380 1.9E-43 T 28-03-2018 WM46_RS11785 fc82587aa319c2d67fb5238cb5246df5 380 Gene3D G3DSA:3.40.50.720 1 142 5.6E-40 T 28-03-2018 WM46_RS11785 fc82587aa319c2d67fb5238cb5246df5 380 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 1.8E-28 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS11785 fc82587aa319c2d67fb5238cb5246df5 380 SUPERFAMILY SSF55347 128 326 4.58E-31 T 28-03-2018 WM46_RS11785 fc82587aa319c2d67fb5238cb5246df5 380 SUPERFAMILY SSF51735 2 153 2.03E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08940 317fda97e9c46d9816409fc983774936 110 PIRSF PIRSF018100 1 110 1.1E-60 T 28-03-2018 IPR014491 Curli production protein CsgC WM46_RS08940 317fda97e9c46d9816409fc983774936 110 Pfam PF10610 Thin aggregative fimbriae synthesis protein 6 103 7.3E-46 T 28-03-2018 IPR014491 Curli production protein CsgC WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 Gene3D G3DSA:3.40.50.300 385 660 2.9E-52 T 28-03-2018 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 Pfam PF13361 UvrD-like helicase C-terminal domain 277 616 1.9E-75 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 Gene3D G3DSA:3.40.50.300 5 146 2.6E-27 T 28-03-2018 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 Gene3D G3DSA:3.40.50.300 149 282 7.3E-33 T 28-03-2018 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 271 1.2E-75 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 Gene3D G3DSA:3.40.50.300 283 384 1.3E-25 T 28-03-2018 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 TIGRFAM TIGR01075 uvrD: DNA helicase II 6 718 0.0 T 28-03-2018 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 WM46_RS19095 bd79524cf4bcbc32c558a67142b8b47b 720 SUPERFAMILY SSF52540 7 642 3.01E-182 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17160 6e7188c2f1cb1f6617e20ba070e4e7b1 162 Pfam PF04093 rod shape-determining protein MreD 5 155 5.4E-46 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 WM46_RS17160 6e7188c2f1cb1f6617e20ba070e4e7b1 162 PIRSF PIRSF018472 2 162 4.4E-57 T 28-03-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type WM46_RS17160 6e7188c2f1cb1f6617e20ba070e4e7b1 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 9 154 4.0E-42 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 Pfam PF00936 BMC domain 186 256 4.9E-14 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 Pfam PF00936 BMC domain 80 148 2.9E-12 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 SMART SM00877 79 161 3.5E-11 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 SMART SM00877 185 262 1.0E-14 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 TIGRFAM TIGR04501 microcomp_PduB: microcompartment protein PduB 46 270 4.1E-120 T 28-03-2018 IPR030984 Microcompartment protein PduB GO:0005198 WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 SUPERFAMILY SSF143414 185 260 1.06E-11 T 28-03-2018 WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 PIRSF PIRSF012290 38 270 1.0E-108 T 28-03-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 WM46_RS03520 960c60b3816b0853f6a70cd388107d0f 270 SUPERFAMILY SSF143414 79 156 6.02E-9 T 28-03-2018 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF47789 251 325 1.27E-25 T 28-03-2018 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 156 1.7E-23 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 245 308 7.5E-24 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 256 329 2.0E-36 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Gene3D G3DSA:3.30.1360.10 119 231 2.8E-28 T 28-03-2018 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Gene3D G3DSA:3.30.1360.10 4 90 3.1E-19 T 28-03-2018 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF55257 179 231 1.57E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF55257 6 53 1.57E-30 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 SMART SM00662 23 234 3.0E-105 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 317 34.651 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 228 3.9E-24 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 SUPERFAMILY SSF56553 53 178 1.45E-41 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 Gene3D G3DSA:1.10.150.20 245 328 7.6E-29 T 28-03-2018 WM46_RS17420 456bfd9236c5cfd90803aed14a8ec2d0 329 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 316 4.3E-113 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 WM46_RS07185 f00e68556783a494469db9a859401a34 108 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 107 1.7E-46 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 WM46_RS07185 f00e68556783a494469db9a859401a34 108 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 106 22.403 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 WM46_RS07185 f00e68556783a494469db9a859401a34 108 SUPERFAMILY SSF103481 7 105 6.54E-6 T 28-03-2018 WM46_RS13840 d93637d120dd799d00bca949d14d5293 235 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 149 4.8E-60 T 28-03-2018 IPR023370 TsaA-like domain WM46_RS13840 d93637d120dd799d00bca949d14d5293 235 SUPERFAMILY SSF118196 1 229 1.11E-85 T 28-03-2018 IPR023370 TsaA-like domain WM46_RS13840 d93637d120dd799d00bca949d14d5293 235 Pfam PF01980 Uncharacterised protein family UPF0066 21 142 4.3E-40 T 28-03-2018 IPR023370 TsaA-like domain WM46_RS13840 d93637d120dd799d00bca949d14d5293 235 Gene3D G3DSA:3.30.2310.10 150 231 1.1E-24 T 28-03-2018 WM46_RS13840 d93637d120dd799d00bca949d14d5293 235 Gene3D G3DSA:2.40.30.70 5 149 9.0E-52 T 28-03-2018 IPR023370 TsaA-like domain WM46_RS13840 d93637d120dd799d00bca949d14d5293 235 ProSitePatterns PS01318 TsaA-like domain signature. 87 98 - T 28-03-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site WM46_RS03225 11823630abe5ef33534fe70f493b5a41 155 Pfam PF03245 Bacteriophage Rz lysis protein 30 154 1.2E-28 T 28-03-2018 IPR004929 Spanin, inner membrane subunit GO:0019076|GO:0019835 WM46_RS17875 e4f97ff51a8947849e4f84bae644bfb0 75 SMART SM00899 1 72 9.8E-8 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 WM46_RS17875 e4f97ff51a8947849e4f84bae644bfb0 75 Pfam PF04023 FeoA domain 8 71 1.0E-7 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 WM46_RS17875 e4f97ff51a8947849e4f84bae644bfb0 75 Gene3D G3DSA:2.30.30.90 1 75 1.5E-13 T 28-03-2018 WM46_RS17875 e4f97ff51a8947849e4f84bae644bfb0 75 SUPERFAMILY SSF50037 2 73 1.69E-16 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal WM46_RS13765 6fda8fedd8f35bfb41a07c7776818062 256 Gene3D G3DSA:3.40.50.150 30 254 6.8E-43 T 28-03-2018 WM46_RS13765 6fda8fedd8f35bfb41a07c7776818062 256 SUPERFAMILY SSF53335 11 242 8.9E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS13765 6fda8fedd8f35bfb41a07c7776818062 256 Pfam PF08241 Methyltransferase domain 49 145 2.7E-25 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 Gene3D G3DSA:3.20.20.80 1 476 3.2E-155 T 28-03-2018 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site WM46_RS00780 bef52a688fbb2f54413808db72208555 476 Pfam PF00232 Glycosyl hydrolase family 1 4 473 4.3E-132 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 413 430 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 PRINTS PR00131 Glycosyl hydrolase family 1 signature 304 318 2.9E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS00780 bef52a688fbb2f54413808db72208555 476 SUPERFAMILY SSF51445 3 470 3.11E-164 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS00780 bef52a688fbb2f54413808db72208555 476 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site WM46_RS23395 504c837d48a139b373206b4875e45a5d 167 Pfam PF00583 Acetyltransferase (GNAT) family 46 144 1.4E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS23395 504c837d48a139b373206b4875e45a5d 167 Gene3D G3DSA:3.40.630.30 2 151 6.7E-30 T 28-03-2018 WM46_RS23395 504c837d48a139b373206b4875e45a5d 167 SUPERFAMILY SSF55729 8 167 4.46E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS14085 c7ab4a62eab7832d1e8ef0ae80a9f647 234 Pfam PF03749 Sugar fermentation stimulation protein 13 225 5.3E-76 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein WM46_RS14085 c7ab4a62eab7832d1e8ef0ae80a9f647 234 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 231 5.0E-96 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein WM46_RS14085 c7ab4a62eab7832d1e8ef0ae80a9f647 234 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 234 56.53 T 28-03-2018 IPR005224 Sugar fermentation stimulation protein WM46_RS01015 83d45bc7772febb46a6da43b015e914f 298 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 60 297 41.273 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 WM46_RS01015 83d45bc7772febb46a6da43b015e914f 298 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 69 296 5.6E-80 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 WM46_RS01015 83d45bc7772febb46a6da43b015e914f 298 PIRSF PIRSF018982 49 298 1.1E-103 T 28-03-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 Gene3D G3DSA:2.60.120.280 10 205 7.8E-13 T 28-03-2018 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 Pfam PF07883 Cupin domain 29 81 3.5E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 Gene3D G3DSA:1.10.10.60 230 280 2.5E-12 T 28-03-2018 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 268 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 Pfam PF12833 Helix-turn-helix domain 202 273 1.7E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 SMART SM00342 189 272 2.9E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 SUPERFAMILY SSF46689 225 276 7.17E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 Gene3D G3DSA:1.10.10.60 206 229 0.0032 T 28-03-2018 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 256 2.7E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 272 2.7E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS08130 5f9d289679cc24d93f986dcf50bc2e1d 280 SUPERFAMILY SSF51182 30 161 1.89E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS12010 54a16b7d80779f47d3fe161dce59cbb5 841 Pfam PF00577 Outer membrane usher protein 195 750 5.0E-191 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS12010 54a16b7d80779f47d3fe161dce59cbb5 841 Pfam PF13953 PapC C-terminal domain 760 824 1.4E-21 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS12010 54a16b7d80779f47d3fe161dce59cbb5 841 Pfam PF13954 PapC N-terminal domain 34 178 1.4E-38 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS12010 54a16b7d80779f47d3fe161dce59cbb5 841 SUPERFAMILY SSF141729 57 170 1.02E-28 T 28-03-2018 WM46_RS12010 54a16b7d80779f47d3fe161dce59cbb5 841 Gene3D G3DSA:3.40.50.1110 418 654 2.8E-4 T 28-03-2018 WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 Gene3D G3DSA:3.30.70.270 337 496 6.8E-34 T 28-03-2018 WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 Pfam PF00990 Diguanylate cyclase, GGDEF domain 346 495 2.2E-34 T 28-03-2018 IPR000160 GGDEF domain WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 SMART SM00267 333 495 1.9E-36 T 28-03-2018 IPR000160 GGDEF domain WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 Pfam PF17155 Gammaproteobacterial periplasmic sensor domain 32 304 2.8E-129 T 28-03-2018 IPR033420 Gammaproteobacterial periplasmic sensor domain GAPES1 WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 343 495 2.9E-34 T 28-03-2018 IPR000160 GGDEF domain WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 SUPERFAMILY SSF55073 349 495 7.85E-32 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS08370 87576b87a0632eb7a195bdf673b9051a 496 Gene3D G3DSA:3.30.450.20 56 241 1.8E-6 T 28-03-2018 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 Gene3D G3DSA:3.30.160.20 209 291 1.2E-32 T 28-03-2018 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 Pfam PF03462 PCRF domain 13 203 8.1E-76 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 SUPERFAMILY SSF75620 12 353 9.94E-137 T 28-03-2018 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.115 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 4.9E-176 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 Gene3D G3DSA:1.20.58.410 3 100 5.3E-20 T 28-03-2018 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 Pfam PF00472 RF-1 domain 216 321 1.5E-40 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM46_RS05555 0288e481852ab537c912d88eebd4de77 360 SMART SM00937 63 178 2.8E-72 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 WM46_RS15175 83c5b8a7344f6471874afc8480e944d0 541 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 424 538 1.1E-20 T 28-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal WM46_RS15175 83c5b8a7344f6471874afc8480e944d0 541 Gene3D G3DSA:2.40.10.200 441 539 8.7E-23 T 28-03-2018 WM46_RS15175 83c5b8a7344f6471874afc8480e944d0 541 Pfam PF07514 Putative helicase 30 235 1.7E-27 T 28-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative WM46_RS15175 83c5b8a7344f6471874afc8480e944d0 541 SUPERFAMILY SSF46785 421 540 2.12E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15175 83c5b8a7344f6471874afc8480e944d0 541 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 30 237 9.7E-63 T 28-03-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 SUPERFAMILY SSF53784 3 309 3.27E-113 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 Gene3D G3DSA:3.40.50.450 213 307 1.0E-8 T 28-03-2018 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 Gene3D G3DSA:3.40.50.450 1 212 4.9E-82 T 28-03-2018 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 32 45 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 2.1E-81 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 301 4.3E-125 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 PIRSF PIRSF000532 1 320 2.8E-130 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 Pfam PF00365 Phosphofructokinase 4 276 3.8E-106 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 WM46_RS18505 85aa6046aa38b053937bbc5ea59c0f9a 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 2 320 46.796 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 WM46_RS04410 9ed2b5f6cd82d5cd37ca8d3fcc46be4b 112 Pfam PF10709 Protein of unknown function (DUF2511) 25 112 1.6E-43 T 28-03-2018 IPR019648 Protein of unknown function DUF2511 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 Hamap MF_01518 Adenine deaminase [ade]. 31 583 35.282 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 Gene3D G3DSA:2.30.40.10 282 368 1.6E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 SUPERFAMILY SSF51338 333 354 4.51E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 SUPERFAMILY SSF51338 21 85 4.51E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 Gene3D G3DSA:2.30.40.10 28 89 3.5E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 TIGRFAM TIGR01178 ade: adenine deaminase 31 582 2.0E-229 T 28-03-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 Gene3D G3DSA:3.20.20.140 90 271 7.6E-9 T 28-03-2018 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 Pfam PF01979 Amidohydrolase family 82 364 1.8E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 Pfam PF13382 Adenine deaminase C-terminal domain 434 579 2.5E-55 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 WM46_RS19855 5a235ce43f165afa3293ecaf66baa76a 588 SUPERFAMILY SSF51556 85 333 2.22E-26 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 2 126 2.9E-59 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 Gene3D G3DSA:3.90.470.20 1 126 1.5E-36 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 9 87 1.0E-38 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 4 126 26.594 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 SUPERFAMILY SSF56214 3 125 1.26E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 126 6.3E-39 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 WM46_RS00425 632c8c6cb7fe846aa6ad28f75381597f 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 121 9.8E-24 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS11385 6fe1013be3aa8ccf3ffac3c47c665925 155 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 155 2.7E-87 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS11385 6fe1013be3aa8ccf3ffac3c47c665925 155 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 154 27.07 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS11385 6fe1013be3aa8ccf3ffac3c47c665925 155 Gene3D G3DSA:3.40.1280.10 2 154 8.1E-49 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal WM46_RS11385 6fe1013be3aa8ccf3ffac3c47c665925 155 Pfam PF02590 Predicted SPOUT methyltransferase 2 153 5.2E-46 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS11385 6fe1013be3aa8ccf3ffac3c47c665925 155 PIRSF PIRSF004505 1 154 1.0E-39 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS11385 6fe1013be3aa8ccf3ffac3c47c665925 155 SUPERFAMILY SSF75217 2 153 3.3E-50 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases WM46_RS00880 eb65e9c9ecd3872d31310079ec2fc131 66 Pfam PF13980 Uncharacterised protein family (UPF0370) 1 62 1.4E-33 T 28-03-2018 IPR020910 Uncharacterised protein family UPF0370 WM46_RS00880 eb65e9c9ecd3872d31310079ec2fc131 66 Hamap MF_01566 UPF0370 protein YpfN [ypfN]. 1 63 27.131 T 28-03-2018 IPR020910 Uncharacterised protein family UPF0370 WM46_RS17130 39f810849d20bef7aab9ce9bbc269d78 467 Gene3D G3DSA:1.20.1250.20 229 445 1.8E-8 T 28-03-2018 WM46_RS17130 39f810849d20bef7aab9ce9bbc269d78 467 SUPERFAMILY SSF103473 28 406 8.63E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS17130 39f810849d20bef7aab9ce9bbc269d78 467 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 25 462 3.6E-102 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS17130 39f810849d20bef7aab9ce9bbc269d78 467 Gene3D G3DSA:1.20.1250.20 27 224 2.2E-16 T 28-03-2018 WM46_RS17130 39f810849d20bef7aab9ce9bbc269d78 467 Pfam PF13347 MFS/sugar transport protein 27 448 3.7E-82 T 28-03-2018 WM46_RS11705 d0e9aa861ec5fa19f71d93f0c17abce4 677 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 17 501 1.2E-175 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 WM46_RS11705 d0e9aa861ec5fa19f71d93f0c17abce4 677 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 55 503 9.8E-181 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 WM46_RS11705 d0e9aa861ec5fa19f71d93f0c17abce4 677 ProSitePatterns PS01303 BCCT family of transporters signature. 318 327 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 2.3E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 2.3E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 2.3E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 2.3E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 Gene3D G3DSA:1.10.10.10 8 167 3.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 Pfam PF01047 MarR family 53 112 1.4E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 SMART SM00347 46 148 1.9E-32 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site WM46_RS25600 f95b026b72cb8e27a9439ca3e58d4816 176 SUPERFAMILY SSF46785 21 166 2.14E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01290 0ee1fcf6fee71b981da53ad5c6bd0e89 519 SUPERFAMILY SSF55604 441 513 5.89E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS01290 0ee1fcf6fee71b981da53ad5c6bd0e89 519 Gene3D G3DSA:3.30.1360.60 439 515 1.8E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS01290 0ee1fcf6fee71b981da53ad5c6bd0e89 519 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 415 501 1.3E-15 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS01290 0ee1fcf6fee71b981da53ad5c6bd0e89 519 Pfam PF00367 phosphotransferase system, EIIB 445 476 8.7E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS01290 0ee1fcf6fee71b981da53ad5c6bd0e89 519 Pfam PF02378 Phosphotransferase system, EIIC 14 356 1.9E-57 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 Gene3D G3DSA:1.20.1250.20 235 444 1.5E-26 T 28-03-2018 WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 Pfam PF07690 Major Facilitator Superfamily 36 404 7.6E-59 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 Gene3D G3DSA:1.20.1250.20 20 222 1.7E-37 T 28-03-2018 WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 37 420 9.3E-128 T 28-03-2018 WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 38 438 3.6E-145 T 28-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 SUPERFAMILY SSF103473 22 441 7.19E-84 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19695 67191432f84b0480a0797be2ee8911e9 445 PIRSF PIRSF002808 7 444 5.6E-35 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS16260 5f621303862c9a652641808744021421 246 Pfam PF01774 UreD urease accessory protein 26 215 3.3E-46 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 WM46_RS16260 5f621303862c9a652641808744021421 246 Hamap MF_01384 Urease accessory protein UreD [ureD]. 1 230 25.472 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 WM46_RS25255 ad6c5b990bb82eaaed35c0d77f2d3d2f 103 Gene3D G3DSA:1.20.5.1000 27 78 1.9E-4 T 28-03-2018 WM46_RS25255 ad6c5b990bb82eaaed35c0d77f2d3d2f 103 Pfam PF04977 Septum formation initiator 11 89 1.2E-31 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 WM46_RS25255 ad6c5b990bb82eaaed35c0d77f2d3d2f 103 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 36.547 T 28-03-2018 IPR023081 Cell division protein FtsB WM46_RS08080 c3a88add0fcb6a3bb64c3c7bf3fa1737 286 Pfam PF03881 Fructosamine kinase 1 285 3.2E-114 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 WM46_RS08080 c3a88add0fcb6a3bb64c3c7bf3fa1737 286 Gene3D G3DSA:3.90.1200.10 95 277 1.3E-16 T 28-03-2018 WM46_RS08080 c3a88add0fcb6a3bb64c3c7bf3fa1737 286 PIRSF PIRSF006221 1 286 4.5E-94 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 WM46_RS08080 c3a88add0fcb6a3bb64c3c7bf3fa1737 286 SUPERFAMILY SSF56112 3 281 6.91E-41 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS08080 c3a88add0fcb6a3bb64c3c7bf3fa1737 286 Gene3D G3DSA:3.30.200.20 1 91 3.0E-19 T 28-03-2018 WM46_RS07235 b29f218b2cd20c5cf5ee740f91f51cc9 236 Gene3D G3DSA:1.10.3720.10 36 234 6.8E-27 T 28-03-2018 WM46_RS07235 b29f218b2cd20c5cf5ee740f91f51cc9 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 234 9.8E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07235 b29f218b2cd20c5cf5ee740f91f51cc9 236 SUPERFAMILY SSF161098 40 223 3.4E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS04525 7ad6da2fdd0f06b0c8d9d5c41c9cb4ff 126 Gene3D G3DSA:3.30.1450.10 29 119 2.9E-6 T 28-03-2018 WM46_RS04525 7ad6da2fdd0f06b0c8d9d5c41c9cb4ff 126 Pfam PF04355 SmpA / OmlA family 35 110 3.0E-5 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 WM46_RS20850 d75c9df61977af69d6b42574e9c592ea 314 SUPERFAMILY SSF161098 94 308 9.03E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20850 d75c9df61977af69d6b42574e9c592ea 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 308 4.4E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20850 d75c9df61977af69d6b42574e9c592ea 314 Gene3D G3DSA:1.10.3720.10 2 296 8.8E-44 T 28-03-2018 WM46_RS20850 d75c9df61977af69d6b42574e9c592ea 314 TIGRFAM TIGR02789 nickel_nikB: nickel ABC transporter, permease subunit NikB 1 313 8.3E-166 T 28-03-2018 IPR014156 Nickel ABC transporter, permease subunit NikB GO:0015099|GO:0035444 WM46_RS19460 d7019d44459308aac96a4edfa6b3a077 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 1.4E-196 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 WM46_RS19460 d7019d44459308aac96a4edfa6b3a077 330 SUPERFAMILY SSF55681 7 326 8.88E-97 T 28-03-2018 WM46_RS19460 d7019d44459308aac96a4edfa6b3a077 330 Gene3D G3DSA:3.30.930.10 1 329 1.1E-38 T 28-03-2018 WM46_RS19460 d7019d44459308aac96a4edfa6b3a077 330 Pfam PF03590 Aspartate-ammonia ligase 9 244 1.3E-92 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 WM46_RS19460 d7019d44459308aac96a4edfa6b3a077 330 PIRSF PIRSF001555 1 329 4.0E-150 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 WM46_RS19460 d7019d44459308aac96a4edfa6b3a077 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 45.845 T 28-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 Gene3D G3DSA:3.40.50.720 150 182 0.026 T 28-03-2018 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 SUPERFAMILY SSF51905 139 313 5.61E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 155 169 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 47 65 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 110 126 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 95 107 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 1 15 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 182 197 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 358 371 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 278 295 7.4E-18 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 SUPERFAMILY SSF51905 1 195 1.45E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 Pfam PF00743 Flavin-binding monooxygenase-like 2 405 6.7E-41 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 PIRSF PIRSF000332 1 413 2.3E-47 T 28-03-2018 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 Gene3D G3DSA:3.50.50.60 183 427 4.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS22340 87730ec43821d9019dd31362f5f350cd 510 Gene3D G3DSA:3.50.50.60 2 149 1.6E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 Pfam PF03466 LysR substrate binding domain 90 291 2.9E-22 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 SUPERFAMILY SSF53850 90 292 3.62E-27 T 28-03-2018 WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 SUPERFAMILY SSF46785 3 89 1.38E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 1.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 Gene3D G3DSA:1.10.10.10 1 85 1.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 Gene3D G3DSA:3.40.190.10 181 265 6.0E-11 T 28-03-2018 WM46_RS12890 17f638a29d7e90d600b47ccf80bbefba 300 Gene3D G3DSA:3.40.190.10 90 180 2.5E-10 T 28-03-2018 WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 Gene3D G3DSA:3.40.190.10 99 194 6.5E-5 T 28-03-2018 WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 Hamap MF_01607 HTH-type transcriptional regulator YidZ [yidZ]. 1 319 77.116 T 28-03-2018 IPR023746 Transcription regulator HTH, YidZ GO:0003700|GO:0006355 WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 Gene3D G3DSA:1.10.10.10 2 88 5.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 3.9E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 Pfam PF03466 LysR substrate binding domain 117 312 5.8E-13 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 SUPERFAMILY SSF46785 7 87 2.27E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 Gene3D G3DSA:3.40.190.10 195 281 1.0E-10 T 28-03-2018 WM46_RS19595 d7789e94bfbbac93f69dc3673e1e18cf 319 SUPERFAMILY SSF53850 98 314 8.69E-25 T 28-03-2018 WM46_RS20145 193551c334537d6ab32739c47fce1a80 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.2E-27 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS20145 193551c334537d6ab32739c47fce1a80 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.212 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS20145 193551c334537d6ab32739c47fce1a80 78 SUPERFAMILY SSF143800 2 77 1.26E-29 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS20145 193551c334537d6ab32739c47fce1a80 78 Gene3D G3DSA:2.30.170.40 2 75 3.3E-28 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS20145 193551c334537d6ab32739c47fce1a80 78 Pfam PF00830 Ribosomal L28 family 3 62 1.9E-25 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS05520 6a7111d56520afa83053601c1ba195a3 163 Gene3D G3DSA:3.40.630.30 1 163 3.7E-20 T 28-03-2018 WM46_RS05520 6a7111d56520afa83053601c1ba195a3 163 Pfam PF00583 Acetyltransferase (GNAT) family 25 139 6.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS05520 6a7111d56520afa83053601c1ba195a3 163 SUPERFAMILY SSF55729 2 150 6.08E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS20180 0edfb9a9dbab4bfa06fe37c231a9b419 265 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 20 230 8.1E-66 T 28-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 WM46_RS20180 0edfb9a9dbab4bfa06fe37c231a9b419 265 SUPERFAMILY SSF56112 62 215 2.03E-8 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS20180 0edfb9a9dbab4bfa06fe37c231a9b419 265 Gene3D G3DSA:1.10.510.10 30 252 8.8E-4 T 28-03-2018 WM46_RS20180 0edfb9a9dbab4bfa06fe37c231a9b419 265 PIRSF PIRSF037318 1 265 5.7E-161 T 28-03-2018 IPR017172 Lipopolysaccharide core heptose(I) kinase rfaP GO:0009103|GO:0016301 WM46_RS02655 1be85755bdc02b6ee890307f58e8d5f4 341 Pfam PF00419 Fimbrial protein 182 340 3.7E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS02655 1be85755bdc02b6ee890307f58e8d5f4 341 Gene3D G3DSA:2.60.40.1090 181 341 2.0E-12 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS02655 1be85755bdc02b6ee890307f58e8d5f4 341 SUPERFAMILY SSF49401 192 341 7.95E-11 T 28-03-2018 IPR008966 Adhesion domain WM46_RS02655 1be85755bdc02b6ee890307f58e8d5f4 341 PIRSF PIRSF030811 1 341 2.7E-132 T 28-03-2018 IPR016959 Uncharacterised conserved protein UCP030811 WM46_RS01350 e21188a4e344ee50cca210b68479bbaa 412 Gene3D G3DSA:3.90.1150.10 303 398 1.1E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS01350 e21188a4e344ee50cca210b68479bbaa 412 Gene3D G3DSA:3.40.640.10 51 302 8.0E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS01350 e21188a4e344ee50cca210b68479bbaa 412 Pfam PF00155 Aminotransferase class I and II 37 376 2.4E-59 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS01350 e21188a4e344ee50cca210b68479bbaa 412 SUPERFAMILY SSF53383 10 394 1.75E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 Gene3D G3DSA:3.10.290.10 1 62 3.8E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 SUPERFAMILY SSF55120 61 227 1.44E-46 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 224 1.9E-60 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 SUPERFAMILY SSF55174 1 55 6.62E-12 T 28-03-2018 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 Gene3D G3DSA:3.30.2350.10 63 230 2.6E-39 T 28-03-2018 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 SMART SM00363 1 60 7.5E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 Pfam PF00849 RNA pseudouridylate synthase 62 192 1.1E-18 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS02260 35f507da2bd1679d56f6ad7fce2c3c6f 235 Pfam PF01479 S4 domain 1 45 2.7E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 SUPERFAMILY SSF52540 4 231 1.13E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 Gene3D G3DSA:3.40.50.300 1 253 8.2E-50 T 28-03-2018 WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 Gene3D G3DSA:3.40.50.300 265 496 1.4E-41 T 28-03-2018 WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 SMART SM00382 277 472 6.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 SMART SM00382 29 219 6.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 SUPERFAMILY SSF52540 251 482 7.08E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 Pfam PF00005 ABC transporter 22 169 2.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS19435 ba3cf45781705d4408f50f3566a86285 501 Pfam PF00005 ABC transporter 269 423 2.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS04235 2690ba771f997a2dbdc946ae34a5e4d4 379 Pfam PF07470 Glycosyl Hydrolase Family 88 38 377 5.4E-110 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 WM46_RS04235 2690ba771f997a2dbdc946ae34a5e4d4 379 SUPERFAMILY SSF48208 30 376 4.87E-92 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS04235 2690ba771f997a2dbdc946ae34a5e4d4 379 Gene3D G3DSA:1.50.10.10 1 379 1.7E-80 T 28-03-2018 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 Gene3D G3DSA:1.10.10.10 1 76 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 Gene3D G3DSA:3.40.1410.10 77 240 2.4E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 SUPERFAMILY SSF46785 8 99 4.77E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 SMART SM00866 97 234 1.3E-33 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 Pfam PF07702 UTRA domain 98 234 9.8E-36 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 12 240 1.3E-102 T 28-03-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.1E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 SUPERFAMILY SSF64288 64 239 4.24E-42 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.3E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.3E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS10615 f0b6cc778bbb00b8223171c6ebffe772 241 SMART SM00345 17 76 2.5E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 287 4.6E-26 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 SUPERFAMILY SSF161111 8 207 6.8E-52 T 28-03-2018 WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 SUPERFAMILY SSF160240 209 288 1.83E-25 T 28-03-2018 WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 Pfam PF01545 Cation efflux family 14 206 1.8E-46 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 Hamap MF_01425 Ferrous-iron efflux pump FieF [fieF]. 1 300 65.647 T 28-03-2018 IPR023783 Cation efflux pump FieF GO:0006829|GO:0015684|GO:0016021|GO:0046873 WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 Gene3D G3DSA:1.20.1510.10 8 206 7.1E-42 T 28-03-2018 WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 Gene3D G3DSA:3.30.70.1350 207 290 1.5E-24 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain WM46_RS18510 9d877ab9916091f8e703aa3b3c340b31 300 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 288 2.8E-80 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 Gene3D G3DSA:3.40.47.10 261 408 1.7E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 364 1.1E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 SMART SM00825 Beta-ketoacyl synthase 5 408 3.5E-12 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 Gene3D G3DSA:3.40.47.10 5 260 1.6E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 SUPERFAMILY SSF53901 216 408 5.38E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 247 1.5E-42 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM46_RS18320 042b3e91b872689a956a1d46ea316ac0 409 SUPERFAMILY SSF53901 3 252 1.58E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS03525 e224b774648117167d13f6cc6bfedf66 94 SMART SM00877 4 80 5.4E-36 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03525 e224b774648117167d13f6cc6bfedf66 94 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 48 7.0E-20 T 28-03-2018 WM46_RS03525 e224b774648117167d13f6cc6bfedf66 94 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 22 41 - T 28-03-2018 IPR020808 Bacterial microcompartments protein, conserved site WM46_RS03525 e224b774648117167d13f6cc6bfedf66 94 Pfam PF00936 BMC domain 5 80 1.3E-28 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03525 e224b774648117167d13f6cc6bfedf66 94 SUPERFAMILY SSF143414 4 90 5.23E-32 T 28-03-2018 WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 SUPERFAMILY SSF54862 1 141 9.31E-40 T 28-03-2018 WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 Gene3D G3DSA:3.30.70.20 71 111 7.4E-17 T 28-03-2018 WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 Gene3D G3DSA:3.30.70.20 112 153 1.0E-6 T 28-03-2018 WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 Pfam PF13247 4Fe-4S dicluster domain 54 141 3.9E-14 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 Pfam PF12800 4Fe-4S binding domain 11 22 0.54 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 Gene3D G3DSA:3.30.70.20 2 19 0.023 T 28-03-2018 WM46_RS20410 188d7e41e58ebba9dcc6ca30c79343c3 157 Gene3D G3DSA:3.30.70.20 20 70 9.4E-9 T 28-03-2018 WM46_RS21725 72fdcb60b8c4237aea6e81c65d25b035 548 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 546 1.1E-249 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 WM46_RS21725 72fdcb60b8c4237aea6e81c65d25b035 548 Pfam PF00999 Sodium/hydrogen exchanger family 7 421 8.8E-78 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 WM46_RS23990 38e6fb4ef48a033d238b7bdb6532325a 240 SUPERFAMILY SSF46894 144 209 1.67E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS23990 38e6fb4ef48a033d238b7bdb6532325a 240 Gene3D G3DSA:1.10.10.10 42 216 1.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23990 38e6fb4ef48a033d238b7bdb6532325a 240 SMART SM00421 151 208 5.3E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS23990 38e6fb4ef48a033d238b7bdb6532325a 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 7.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS10080 d0d745fbf1f2443bc81f00a6d50dc7ac 333 Pfam PF01212 Beta-eliminating lyase 3 282 1.9E-96 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 WM46_RS10080 d0d745fbf1f2443bc81f00a6d50dc7ac 333 Gene3D G3DSA:3.90.1150.10 248 333 1.8E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS10080 d0d745fbf1f2443bc81f00a6d50dc7ac 333 SUPERFAMILY SSF53383 1 332 6.78E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS10080 d0d745fbf1f2443bc81f00a6d50dc7ac 333 PIRSF PIRSF017617 1 333 5.0E-130 T 28-03-2018 IPR023603 Threonine aldolase WM46_RS10080 d0d745fbf1f2443bc81f00a6d50dc7ac 333 Gene3D G3DSA:3.40.640.10 17 247 3.9E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 SUPERFAMILY SSF53671 4 306 7.59E-100 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 307 37.963 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.6E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 3.6E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 226 235 3.6E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 3.6E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 3.6E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 3.6E-36 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 Gene3D G3DSA:3.40.50.1370 1 146 2.2E-52 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 305 9.2E-125 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 4.5E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.5E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 4.5E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.5E-25 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.3E-47 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 303 9.6E-28 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 Gene3D G3DSA:3.40.50.1370 147 292 3.6E-48 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS23315 32900321a7ae25747477f224e1ddb1bc 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 WM46_RS16525 76acd8f7ffaba2415571dd1ee27eac9d 381 PIRSF PIRSF006078 1 377 1.4E-139 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS16525 76acd8f7ffaba2415571dd1ee27eac9d 381 SUPERFAMILY SSF110738 1 375 1.2E-140 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS16525 76acd8f7ffaba2415571dd1ee27eac9d 381 Pfam PF02595 Glycerate kinase family 3 373 1.8E-148 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS16525 76acd8f7ffaba2415571dd1ee27eac9d 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 374 8.9E-169 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS16525 76acd8f7ffaba2415571dd1ee27eac9d 381 Gene3D G3DSA:3.90.1510.10 42 276 3.7E-96 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 WM46_RS00755 5b25323ff29119169e56999d141bedf9 746 SMART SM00052 492 735 2.9E-99 T 28-03-2018 IPR001633 EAL domain WM46_RS00755 5b25323ff29119169e56999d141bedf9 746 Gene3D G3DSA:3.20.20.450 483 738 8.6E-74 T 28-03-2018 IPR001633 EAL domain WM46_RS00755 5b25323ff29119169e56999d141bedf9 746 SMART SM00267 319 480 3.0E-6 T 28-03-2018 IPR000160 GGDEF domain WM46_RS00755 5b25323ff29119169e56999d141bedf9 746 Pfam PF05231 MASE1 15 320 9.1E-63 T 28-03-2018 IPR007895 MASE1 WM46_RS00755 5b25323ff29119169e56999d141bedf9 746 SUPERFAMILY SSF141868 497 737 1.7E-70 T 28-03-2018 IPR001633 EAL domain WM46_RS00755 5b25323ff29119169e56999d141bedf9 746 Pfam PF00563 EAL domain 498 730 1.5E-65 T 28-03-2018 IPR001633 EAL domain WM46_RS16555 33077162f8f73d3b64f1a1f278074ed9 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 312 7.4E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS16555 33077162f8f73d3b64f1a1f278074ed9 314 Gene3D G3DSA:1.20.58.370 21 63 5.1E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain WM46_RS16555 33077162f8f73d3b64f1a1f278074ed9 314 Gene3D G3DSA:1.10.3720.10 81 311 7.8E-44 T 28-03-2018 WM46_RS16555 33077162f8f73d3b64f1a1f278074ed9 314 SUPERFAMILY SSF161098 74 303 4.97E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS08770 7c1955cb15d3efbff38fe4987dd59190 251 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 170 247 1.8E-21 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain WM46_RS08770 7c1955cb15d3efbff38fe4987dd59190 251 SUPERFAMILY SSF117143 77 209 2.88E-17 T 28-03-2018 WM46_RS08770 7c1955cb15d3efbff38fe4987dd59190 251 Pfam PF00460 Flagella basal body rod protein 5 35 2.1E-10 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 WM46_RS08770 7c1955cb15d3efbff38fe4987dd59190 251 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 120 2.9E-32 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G WM46_RS08770 7c1955cb15d3efbff38fe4987dd59190 251 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site WM46_RS08155 563dba780a65615c9dbaf86ebb5b909e 275 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 275 7.9E-83 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 WM46_RS08155 563dba780a65615c9dbaf86ebb5b909e 275 SUPERFAMILY SSF52402 3 273 5.67E-86 T 28-03-2018 WM46_RS08155 563dba780a65615c9dbaf86ebb5b909e 275 Pfam PF02540 NAD synthase 23 265 5.2E-77 T 28-03-2018 IPR022310 NAD/GMP synthase WM46_RS08155 563dba780a65615c9dbaf86ebb5b909e 275 Gene3D G3DSA:3.40.50.620 2 274 1.0E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS08155 563dba780a65615c9dbaf86ebb5b909e 275 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 268 31.399 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 467 20.408 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PIRSF PIRSF002869 1 511 5.1E-181 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 Pfam PF03023 MviN-like protein 28 478 2.0E-159 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 33 52 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 357 376 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 409 426 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 52 68 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 259 285 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 157 178 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 PRINTS PR01806 Virulence factor MviN signature 133 157 2.8E-87 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS08815 c1c32c3c23b9a99bb6801a5be648fb91 511 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 508 4.4E-178 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 2 392 40.969 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 Pfam PF13360 PQQ-like domain 78 319 6.3E-54 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 8 390 3.6E-134 T 28-03-2018 IPR017687 Outer membrane protein assembly factor BamB WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 155 186 5.5E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 251 282 3.1E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 289 320 250.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 329 361 6.5E-4 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 64 96 7.6E-5 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 114 146 1.3E-4 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SMART SM00564 200 231 110.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 Gene3D G3DSA:2.140.10.10 236 365 1.8E-21 T 28-03-2018 WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 Gene3D G3DSA:2.140.10.10 27 194 5.3E-32 T 28-03-2018 WM46_RS00720 8db4b691c117ea0474e2aa653e5d2d8b 392 SUPERFAMILY SSF50998 34 382 2.01E-79 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 SMART SM01130 6 295 5.7E-70 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 4.2E-11 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 4.2E-11 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 4.2E-11 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 106 122 4.2E-11 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 PIRSF PIRSF001365 2 296 4.0E-65 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 SUPERFAMILY SSF51569 9 294 3.24E-69 T 28-03-2018 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 Gene3D G3DSA:3.20.20.70 2 296 2.5E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS18535 91ad2c337fba9e130f32c3d1223e4a07 296 Pfam PF00701 Dihydrodipicolinate synthetase family 7 265 1.4E-49 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 Pfam PF01494 FAD binding domain 2 338 8.1E-21 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 SUPERFAMILY SSF51905 265 382 2.36E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 SUPERFAMILY SSF51905 2 175 2.36E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 292 305 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.2E-13 T 28-03-2018 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.2E-13 T 28-03-2018 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 1.2E-13 T 28-03-2018 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.2E-13 T 28-03-2018 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 3 388 1.4E-141 T 28-03-2018 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 Gene3D G3DSA:3.50.50.60 2 352 6.3E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS24190 46f3c9486dcf68b690473496cb8e8801 392 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 3 387 2.4E-134 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 WM46_RS16095 ea3b7f4055c1e3c4f314baff1d2b103e 606 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 14 355 2.9E-122 T 28-03-2018 IPR016624 Uncharacterised conserved protein UCP014753 WM46_RS16095 ea3b7f4055c1e3c4f314baff1d2b103e 606 PIRSF PIRSF014753 3 602 6.5E-169 T 28-03-2018 IPR016624 Uncharacterised conserved protein UCP014753 WM46_RS25290 a31fcc4f7a8798d109ee663b2fba8aea 375 Pfam PF01551 Peptidase family M23 275 368 1.2E-31 T 28-03-2018 IPR016047 Peptidase M23 WM46_RS25290 a31fcc4f7a8798d109ee663b2fba8aea 375 SUPERFAMILY SSF51261 118 372 5.75E-53 T 28-03-2018 IPR011055 Duplicated hybrid motif WM46_RS25290 a31fcc4f7a8798d109ee663b2fba8aea 375 Pfam PF01476 LysM domain 119 161 4.1E-11 T 28-03-2018 IPR018392 LysM domain WM46_RS25290 a31fcc4f7a8798d109ee663b2fba8aea 375 Gene3D G3DSA:2.70.70.10 241 375 2.3E-38 T 28-03-2018 WM46_RS25290 a31fcc4f7a8798d109ee663b2fba8aea 375 Gene3D G3DSA:3.10.350.10 107 240 8.5E-11 T 28-03-2018 WM46_RS25290 a31fcc4f7a8798d109ee663b2fba8aea 375 SMART SM00257 118 162 1.0E-10 T 28-03-2018 IPR018392 LysM domain WM46_RS08120 3ec141a0789c21d8b162ee657fc1f124 252 Gene3D G3DSA:3.20.20.370 1 252 3.0E-78 T 28-03-2018 WM46_RS08120 3ec141a0789c21d8b162ee657fc1f124 252 Pfam PF04794 YdjC-like protein 5 240 3.7E-59 T 28-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like WM46_RS08120 3ec141a0789c21d8b162ee657fc1f124 252 SUPERFAMILY SSF88713 1 252 1.69E-75 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS08120 3ec141a0789c21d8b162ee657fc1f124 252 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 3 249 40.263 T 28-03-2018 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 Gene3D G3DSA:3.40.50.300 2 236 8.1E-34 T 28-03-2018 WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 Pfam PF00005 ABC transporter 23 163 2.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 Pfam PF00005 ABC transporter 276 429 7.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 SMART SM00382 28 219 1.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 SMART SM00382 285 480 8.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 SUPERFAMILY SSF52540 260 475 1.74E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 SUPERFAMILY SSF52540 4 225 2.58E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10695 64d447689839568d2bdefad1cd5faced 490 Gene3D G3DSA:3.40.50.300 243 487 4.6E-43 T 28-03-2018 WM46_RS22085 342b7fcc5c6d2bce19fd51d60cd2fdd7 65 Pfam PF15959 Domain of unknown function (DUF4762) 1 60 8.5E-29 T 28-03-2018 IPR031882 Protein of unknown function DUF4762 WM46_RS01650 9f3e987484b3ea686794a95567cfc9fb 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 214 1.8E-25 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS01650 9f3e987484b3ea686794a95567cfc9fb 297 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 292 7.3E-110 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 WM46_RS01650 9f3e987484b3ea686794a95567cfc9fb 297 Gene3D G3DSA:3.40.50.720 1 297 5.0E-42 T 28-03-2018 WM46_RS01650 9f3e987484b3ea686794a95567cfc9fb 297 SUPERFAMILY SSF51735 1 296 7.47E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS01650 9f3e987484b3ea686794a95567cfc9fb 297 Pfam PF08338 Domain of unknown function (DUF1731) 249 295 2.1E-18 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 WM46_RS12160 d00304fa553106c504ecce23313badf6 65 Gene3D G3DSA:1.10.10.10 7 65 1.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12160 d00304fa553106c504ecce23313badf6 65 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 5 53 1.2E-16 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA WM46_RS07565 609006231c3f325da55e5867050f47ec 369 SUPERFAMILY SSF49401 225 369 2.54E-18 T 28-03-2018 IPR008966 Adhesion domain WM46_RS07565 609006231c3f325da55e5867050f47ec 369 Gene3D G3DSA:2.60.40.1090 220 369 2.0E-25 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07565 609006231c3f325da55e5867050f47ec 369 Pfam PF00419 Fimbrial protein 222 369 2.3E-16 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS11325 f788aa1c6c48c0579b364687f7b15157 246 SUPERFAMILY SSF161098 24 223 7.85E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS11325 f788aa1c6c48c0579b364687f7b15157 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 238 5.0E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS11325 f788aa1c6c48c0579b364687f7b15157 246 Gene3D G3DSA:1.10.3720.10 17 239 1.2E-38 T 28-03-2018 WM46_RS11325 f788aa1c6c48c0579b364687f7b15157 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 132 1.8E-15 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS23300 33622f1fa5d4328ac06dd81246eba51f 428 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 422 2.0E-130 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 WM46_RS23300 33622f1fa5d4328ac06dd81246eba51f 428 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 10 417 3.7E-113 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit WM46_RS23300 33622f1fa5d4328ac06dd81246eba51f 428 PIRSF PIRSF006066 1 428 1.1E-175 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 WM46_RS05405 9488e0460d084cc50d128dcce02bafa1 309 Gene3D G3DSA:1.10.150.130 15 121 2.9E-5 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS05405 9488e0460d084cc50d128dcce02bafa1 309 SUPERFAMILY SSF56349 22 292 7.06E-43 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS05405 9488e0460d084cc50d128dcce02bafa1 309 Pfam PF00589 Phage integrase family 125 291 6.4E-32 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS05405 9488e0460d084cc50d128dcce02bafa1 309 Gene3D G3DSA:1.10.443.10 122 301 1.6E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS10420 63bef8919a20f5b6aa2ce538071d5dc5 240 Pfam PF00005 ABC transporter 17 165 1.0E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10420 63bef8919a20f5b6aa2ce538071d5dc5 240 SMART SM00382 26 213 2.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10420 63bef8919a20f5b6aa2ce538071d5dc5 240 Gene3D G3DSA:3.40.50.300 1 240 9.3E-77 T 28-03-2018 WM46_RS10420 63bef8919a20f5b6aa2ce538071d5dc5 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10420 63bef8919a20f5b6aa2ce538071d5dc5 240 SUPERFAMILY SSF52540 1 235 1.69E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10420 63bef8919a20f5b6aa2ce538071d5dc5 240 PIRSF PIRSF039085 1 240 4.5E-110 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS22075 2ec05bb409684bd55fa963169bedae1b 182 Pfam PF00419 Fimbrial protein 33 182 2.1E-17 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22075 2ec05bb409684bd55fa963169bedae1b 182 Gene3D G3DSA:2.60.40.1090 29 182 2.3E-30 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS22075 2ec05bb409684bd55fa963169bedae1b 182 SUPERFAMILY SSF49401 31 182 2.63E-34 T 28-03-2018 IPR008966 Adhesion domain WM46_RS02870 8f83cbefa39949962f97e252ced168a3 464 Pfam PF02397 Bacterial sugar transferase 274 456 2.0E-67 T 28-03-2018 IPR003362 Bacterial sugar transferase WM46_RS02870 8f83cbefa39949962f97e252ced168a3 464 Gene3D G3DSA:3.40.50.720 141 263 6.5E-14 T 28-03-2018 WM46_RS02870 8f83cbefa39949962f97e252ced168a3 464 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 28 464 2.5E-165 T 28-03-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 WM46_RS02870 8f83cbefa39949962f97e252ced168a3 464 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 28 464 3.1E-150 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase WM46_RS02870 8f83cbefa39949962f97e252ced168a3 464 SUPERFAMILY SSF51735 143 269 2.68E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02870 8f83cbefa39949962f97e252ced168a3 464 Pfam PF13727 CoA-binding domain 65 238 1.0E-39 T 28-03-2018 WM46_RS20925 32707d33b60f7de74baed35eb1acfa68 301 Pfam PF00892 EamA-like transporter family 15 141 2.6E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS20925 32707d33b60f7de74baed35eb1acfa68 301 Pfam PF00892 EamA-like transporter family 152 289 3.6E-26 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS20925 32707d33b60f7de74baed35eb1acfa68 301 SUPERFAMILY SSF103481 44 144 3.14E-14 T 28-03-2018 WM46_RS20925 32707d33b60f7de74baed35eb1acfa68 301 SUPERFAMILY SSF103481 189 293 9.81E-17 T 28-03-2018 WM46_RS25330 4448faee84bd406f01012c9a4e6ddde4 285 Pfam PF00950 ABC 3 transport family 10 264 2.7E-83 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 WM46_RS25330 4448faee84bd406f01012c9a4e6ddde4 285 SUPERFAMILY SSF81345 3 260 1.44E-38 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS25330 4448faee84bd406f01012c9a4e6ddde4 285 Gene3D G3DSA:1.10.3470.10 3 272 6.1E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS03585 2702c30fdea377c53880b0a841eeb5e1 241 SUPERFAMILY SSF53790 1 239 9.03E-57 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03585 2702c30fdea377c53880b0a841eeb5e1 241 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 2 239 1.3E-106 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 WM46_RS03585 2702c30fdea377c53880b0a841eeb5e1 241 Gene3D G3DSA:3.30.950.10 121 238 1.4E-51 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03585 2702c30fdea377c53880b0a841eeb5e1 241 Gene3D G3DSA:3.40.1010.10 1 120 5.8E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03585 2702c30fdea377c53880b0a841eeb5e1 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 208 2.4E-39 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 Gene3D G3DSA:3.30.230.10 1 119 1.0E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 115 17.811 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 Pfam PF00825 Ribonuclease P 6 111 2.2E-32 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 17 105 7.0E-46 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 SUPERFAMILY SSF54211 5 115 5.06E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 56 70 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 WM46_RS19640 4db93651077c9c1c8de38ae49c42199e 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 5 115 2.2E-37 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 8 382 8.0E-158 T 28-03-2018 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 Gene3D G3DSA:3.20.20.70 2 340 1.2E-36 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 Pfam PF04055 Radical SAM superfamily 15 185 1.1E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 Pfam PF13186 Iron-sulfur cluster-binding domain 276 336 2.3E-7 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 SUPERFAMILY SSF102114 16 345 5.76E-41 T 28-03-2018 WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 168 398 7.0E-21 T 28-03-2018 WM46_RS14735 8e889cf0ada8ffce7c959d51d0cb88d6 399 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 275 364 7.5E-20 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Gene3D G3DSA:3.40.50.720 233 366 5.0E-25 T 28-03-2018 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 SUPERFAMILY SSF116726 148 226 1.26E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 SUPERFAMILY SSF51735 232 376 2.8E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Pfam PF02080 TrkA-C domain 390 451 1.3E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Pfam PF02080 TrkA-C domain 157 225 1.6E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Gene3D G3DSA:3.30.70.1450 367 458 3.4E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.5E-36 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.5E-36 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.5E-36 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.5E-36 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.5E-36 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 SUPERFAMILY SSF51735 1 152 2.24E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Pfam PF02254 TrkA-N domain 235 350 2.7E-26 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Pfam PF02254 TrkA-N domain 3 111 8.6E-30 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Gene3D G3DSA:3.30.70.1450 140 232 1.3E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 SUPERFAMILY SSF116726 390 450 1.57E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 WM46_RS17390 1607ec82929f58607190cd7949b412be 458 Gene3D G3DSA:3.40.50.720 2 139 2.7E-27 T 28-03-2018 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 223 40.331 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 Gene3D G3DSA:3.20.20.70 25 219 3.1E-12 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 Pfam PF13394 4Fe-4S single cluster domain 24 128 1.4E-13 T 28-03-2018 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 Pfam PF04055 Radical SAM superfamily 27 181 1.0E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 PIRSF PIRSF000370 1 223 1.1E-73 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 9 223 4.2E-112 T 28-03-2018 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 WM46_RS25150 c0d9e1ea1243001e7b477267d25547a7 223 SUPERFAMILY SSF102114 24 119 1.96E-7 T 28-03-2018 WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 Pfam PF00135 Carboxylesterase family 353 474 2.4E-12 T 28-03-2018 IPR002018 Carboxylesterase, type B WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 Pfam PF00135 Carboxylesterase family 8 328 1.3E-87 T 28-03-2018 IPR002018 Carboxylesterase, type B WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 182 197 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 84 94 - T 28-03-2018 IPR019819 Carboxylesterase type B, conserved site WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 SUPERFAMILY SSF53474 10 497 3.64E-113 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 PRINTS PR00878 Cholinesterase signature 108 137 2.9E-5 T 28-03-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 PRINTS PR00878 Cholinesterase signature 400 412 2.9E-5 T 28-03-2018 IPR000997 Cholinesterase GO:0004104 Reactome: R-HSA-112311|Reactome: R-HSA-1483191|Reactome: R-HSA-422085 WM46_RS06420 18e6e6283b44654a14416cb7b43b037f 502 Gene3D G3DSA:3.40.50.1820 2 501 6.9E-118 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS00565 69c92e7cc5d499e5fbb0d3acdea160d9 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 312 2.4E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS00565 69c92e7cc5d499e5fbb0d3acdea160d9 329 Gene3D G3DSA:1.10.3470.10 35 318 1.5E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 4.7E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 4.7E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 27 4.7E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 347 359 4.7E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 78 90 4.7E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 313 319 4.7E-28 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 Pfam PF01266 FAD dependent oxidoreductase 5 323 5.1E-49 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 Gene3D G3DSA:3.40.50.720 3 84 0.0017 T 28-03-2018 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 SUPERFAMILY SSF51905 312 375 6.91E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 SUPERFAMILY SSF51905 1 260 6.91E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 SUPERFAMILY SSF54373 226 319 6.47E-7 T 28-03-2018 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 381 491 3.1E-13 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 Gene3D G3DSA:3.30.9.10 85 182 4.3E-17 T 28-03-2018 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 Gene3D G3DSA:3.30.9.10 183 320 1.6E-38 T 28-03-2018 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 9 26 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS17980 5ea249dc4bbb58706b8bcf35fdfbc459 502 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 352 362 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 280 2.8E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 543 575 6.5E-8 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 SMART SM00382 41 246 1.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 SMART SM00382 349 540 9.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 Gene3D G3DSA:3.40.50.300 310 598 7.0E-73 T 28-03-2018 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 Gene3D G3DSA:3.40.50.300 9 299 1.1E-67 T 28-03-2018 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 SUPERFAMILY SSF52540 13 268 1.59E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 Pfam PF00005 ABC transporter 341 490 2.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 Pfam PF00005 ABC transporter 33 196 1.2E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10285 4217f0401d23b87cd1a8b97a6f2dace1 623 SUPERFAMILY SSF52540 313 563 5.77E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 Gene3D G3DSA:2.40.50.100 51 80 0.0019 T 28-03-2018 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 Pfam PF13533 Biotin-lipoyl like 68 100 2.1E-7 T 28-03-2018 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 Gene3D G3DSA:2.40.50.100 81 275 1.5E-14 T 28-03-2018 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 Pfam PF13437 HlyD family secretion protein 245 347 9.2E-15 T 28-03-2018 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 32 55 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 376 396 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 74 94 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 291 315 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 361 376 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 315 338 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS00115 e8dfc396d6a7c265f935bd5f5ec2bcd9 396 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 258 279 2.0E-36 T 28-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 41 53 1.8E-69 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 108 135 1.8E-69 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 9 35 1.8E-69 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 86 108 1.8E-69 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 254 279 1.8E-69 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 232 254 1.8E-69 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 Pfam PF00551 Formyl transferase 86 262 7.0E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 4 280 46.256 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 Gene3D G3DSA:3.40.50.170 80 277 5.0E-53 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 280 4.3E-132 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 Pfam PF01842 ACT domain 8 69 5.7E-8 T 28-03-2018 IPR002912 ACT domain WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 PIRSF PIRSF036480 4 280 2.3E-114 T 28-03-2018 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 SUPERFAMILY SSF55021 6 56 4.58E-9 T 28-03-2018 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 Gene3D G3DSA:3.30.70.260 5 79 1.8E-8 T 28-03-2018 WM46_RS05695 0efb022ece8babe9c97dafa9bd4ebd10 280 SUPERFAMILY SSF53328 86 279 1.57E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 SUPERFAMILY SSF55681 407 478 8.56E-110 T 28-03-2018 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 SUPERFAMILY SSF55681 10 237 8.56E-110 T 28-03-2018 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 571 43.259 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 PIRSF PIRSF001535 1 572 1.7E-278 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 SUPERFAMILY SSF55826 219 390 4.58E-32 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 Pfam PF04073 Aminoacyl-tRNA editing domain 257 376 1.3E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 SUPERFAMILY SSF52954 463 571 1.34E-33 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 Gene3D G3DSA:3.40.50.800 461 572 1.9E-32 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 Gene3D G3DSA:3.30.930.10 11 460 1.7E-102 T 28-03-2018 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 Pfam PF03129 Anticodon binding domain 475 568 8.0E-21 T 28-03-2018 IPR004154 Anticodon-binding WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 459 4.0E-49 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.2E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.2E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.2E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.2E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 WM46_RS13845 f28ea75ceacea2e7f495bacbb0d4cb94 572 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 569 5.6E-281 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 Gene3D G3DSA:3.60.150.10 3 358 7.9E-162 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 8.9E-140 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 Pfam PF01264 Chorismate synthase 10 345 5.7E-143 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 PIRSF PIRSF001456 3 359 1.4E-141 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.756 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS01505 1d64d1d1e5fd6ff268bf0736f1ef4956 361 SUPERFAMILY SSF103263 4 353 1.7E-148 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 WM46_RS13590 b41fab6fb9117ca4a41d17ba31f78b7c 182 Gene3D G3DSA:2.40.50.140 1 180 1.8E-44 T 28-03-2018 WM46_RS13590 b41fab6fb9117ca4a41d17ba31f78b7c 182 Pfam PF10991 Protein of unknown function (DUF2815) 2 173 7.0E-48 T 28-03-2018 IPR022595 Protein of unknown function DUF2815 WM46_RS13590 b41fab6fb9117ca4a41d17ba31f78b7c 182 SUPERFAMILY SSF50249 6 173 8.74E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS12955 29082e8c52f27b8d7b92913fff3fb91a 63 Pfam PF16362 YaiA protein 1 62 2.5E-40 T 28-03-2018 IPR032303 YaiA protein WM46_RS08290 6db9188efae72938456de671702f99e1 183 PIRSF PIRSF000232 1 182 6.3E-68 T 28-03-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like WM46_RS08290 6db9188efae72938456de671702f99e1 183 SUPERFAMILY SSF55469 1 168 2.75E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS08290 6db9188efae72938456de671702f99e1 183 Gene3D G3DSA:3.40.109.10 1 183 1.3E-32 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS08290 6db9188efae72938456de671702f99e1 183 Pfam PF00881 Nitroreductase family 9 161 1.4E-24 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 WM46_RS05825 9f2e59e44429b4bd904e3abed8c3d0d2 487 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 343 486 1.2E-34 T 28-03-2018 IPR000160 GGDEF domain WM46_RS05825 9f2e59e44429b4bd904e3abed8c3d0d2 487 SMART SM00267 332 487 1.0E-27 T 28-03-2018 IPR000160 GGDEF domain WM46_RS05825 9f2e59e44429b4bd904e3abed8c3d0d2 487 SUPERFAMILY SSF55073 347 486 6.28E-33 T 28-03-2018 IPR029787 Nucleotide cyclase WM46_RS05825 9f2e59e44429b4bd904e3abed8c3d0d2 487 Pfam PF00990 Diguanylate cyclase, GGDEF domain 343 486 1.9E-31 T 28-03-2018 IPR000160 GGDEF domain WM46_RS05825 9f2e59e44429b4bd904e3abed8c3d0d2 487 Gene3D G3DSA:3.30.70.270 339 487 1.8E-35 T 28-03-2018 WM46_RS24530 b66f5eb91e6c485761f482dd398aae70 833 SUPERFAMILY SSF141729 60 170 5.89E-26 T 28-03-2018 WM46_RS24530 b66f5eb91e6c485761f482dd398aae70 833 Pfam PF13953 PapC C-terminal domain 763 818 1.6E-11 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS24530 b66f5eb91e6c485761f482dd398aae70 833 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 305 315 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS24530 b66f5eb91e6c485761f482dd398aae70 833 Pfam PF00577 Outer membrane usher protein 194 750 2.1E-191 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS24530 b66f5eb91e6c485761f482dd398aae70 833 Pfam PF13954 PapC N-terminal domain 34 179 7.7E-39 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS06295 1a1a888b731f68e14537d925b194a168 879 Pfam PF11739 Dicarboxylate transport 657 858 2.5E-61 T 28-03-2018 IPR021730 Dicarboxylate transport WM46_RS16710 24dc9ae80575e3c3906475b692b92e23 174 SUPERFAMILY SSF55718 42 137 8.71E-22 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS16710 24dc9ae80575e3c3906475b692b92e23 174 Gene3D G3DSA:3.30.1050.10 22 140 1.4E-16 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS16710 24dc9ae80575e3c3906475b692b92e23 174 Pfam PF02036 SCP-2 sterol transfer family 44 133 5.5E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain WM46_RS16710 24dc9ae80575e3c3906475b692b92e23 174 PIRSF PIRSF025550 1 173 7.7E-81 T 28-03-2018 IPR016830 Uncharacterised conserved protein UCP025550, lipid carrier protein, YhbT WM46_RS12090 b415cff8436b479e7360f32044987ddc 485 Gene3D G3DSA:3.90.550.10 10 212 4.6E-12 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS12090 b415cff8436b479e7360f32044987ddc 485 SUPERFAMILY SSF53448 10 205 1.13E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 PIRSF PIRSF039144 1 112 9.8E-53 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 SUPERFAMILY SSF54913 1 112 4.13E-42 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 SMART SM00938 4 105 5.0E-61 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 PRINTS PR00340 P-II protein signature 83 103 4.1E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 PRINTS PR00340 P-II protein signature 2 17 4.1E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 PRINTS PR00340 P-II protein signature 52 75 4.1E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 PRINTS PR00340 P-II protein signature 23 41 4.1E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.9E-41 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 WM46_RS12560 cf694437af3ddb7049c669fc92e59b16 112 Gene3D G3DSA:3.30.70.120 1 108 1.1E-45 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM46_RS23540 a8ae149ae2f919d8f8527b54b891866e 241 SUPERFAMILY SSF53474 180 224 4.73E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23540 a8ae149ae2f919d8f8527b54b891866e 241 SUPERFAMILY SSF53474 15 151 4.73E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23540 a8ae149ae2f919d8f8527b54b891866e 241 Gene3D G3DSA:3.40.50.1820 2 236 7.7E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23540 a8ae149ae2f919d8f8527b54b891866e 241 Pfam PF01738 Dienelactone hydrolase family 21 221 1.3E-8 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 WM46_RS23830 3ce545ba333808a003de47b5f294ad55 453 Gene3D G3DSA:1.20.1250.20 2 208 1.0E-37 T 28-03-2018 WM46_RS23830 3ce545ba333808a003de47b5f294ad55 453 Pfam PF07690 Major Facilitator Superfamily 14 390 6.4E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS23830 3ce545ba333808a003de47b5f294ad55 453 Gene3D G3DSA:1.20.1250.20 217 446 6.8E-28 T 28-03-2018 WM46_RS23830 3ce545ba333808a003de47b5f294ad55 453 SUPERFAMILY SSF103473 4 425 5.23E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS23830 3ce545ba333808a003de47b5f294ad55 453 PIRSF PIRSF002808 1 441 4.0E-40 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS06300 2df72f47a6899cc00e23cb1ea924fee0 63 ProDom PD052969 LIPOPROTEIN PRECURSOR SIGNAL YNBE MEMBRANE OUTER POSSIBLE SIMILAR ECS2004 SO2063 16 63 1.0E-19 T 28-03-2018 WM46_RS06300 2df72f47a6899cc00e23cb1ea924fee0 63 Pfam PF13617 YnbE-like lipoprotein 7 61 5.8E-29 T 28-03-2018 IPR025985 YnbE-like lipoprotein WM46_RS25180 5a07b8f3d3ad2e7bc742c54d5e70e0f0 260 Pfam PF01012 Electron transfer flavoprotein domain 47 210 4.1E-13 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS25180 5a07b8f3d3ad2e7bc742c54d5e70e0f0 260 SUPERFAMILY SSF52402 1 247 8.84E-32 T 28-03-2018 WM46_RS25180 5a07b8f3d3ad2e7bc742c54d5e70e0f0 260 Gene3D G3DSA:3.40.50.620 1 252 3.9E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS25180 5a07b8f3d3ad2e7bc742c54d5e70e0f0 260 SMART SM00893 28 211 0.0012 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 SUPERFAMILY SSF54675 2 138 3.24E-44 T 28-03-2018 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 Gene3D G3DSA:3.20.140.10 1 400 1.1E-104 T 28-03-2018 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 169 394 1.6E-83 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 8 394 2.9E-179 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 PIRSF PIRSF000484 1 397 2.5E-61 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 SUPERFAMILY SSF51690 120 392 2.55E-86 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 WM46_RS09745 537ae2c5a8514625320157a524bfdbd9 400 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 5 395 50.364 T 28-03-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 WM46_RS11565 a9c2255c7e681fbaf42600448f144087 701 Pfam PF02554 Carbon starvation protein CstA 32 404 2.2E-168 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 WM46_RS11565 a9c2255c7e681fbaf42600448f144087 701 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 469 596 4.3E-35 T 28-03-2018 IPR025299 CstA, C-terminal domain WM46_RS09460 8b9459a26336c874f19463120e7691ed 183 Gene3D G3DSA:3.40.630.30 1 85 1.1E-9 T 28-03-2018 WM46_RS09460 8b9459a26336c874f19463120e7691ed 183 Pfam PF00583 Acetyltransferase (GNAT) family 18 121 1.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS09460 8b9459a26336c874f19463120e7691ed 183 SUPERFAMILY SSF55729 5 139 1.35E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS09460 8b9459a26336c874f19463120e7691ed 183 Gene3D G3DSA:3.40.630.30 86 148 1.0E-7 T 28-03-2018 WM46_RS12680 77ac46351e9595f2d9a4d313086c435b 109 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 92 5.9E-19 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 WM46_RS12680 77ac46351e9595f2d9a4d313086c435b 109 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 12 107 2.6E-38 T 28-03-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 10 154 24.447 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 Gene3D G3DSA:3.30.300.70 3 83 1.2E-27 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 Pfam PF02576 RimP N-terminal domain 16 86 1.8E-28 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 SUPERFAMILY SSF74942 87 154 2.22E-16 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 SUPERFAMILY SSF75420 6 86 2.62E-25 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 Gene3D G3DSA:2.30.30.180 91 151 1.2E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal WM46_RS16780 752fb596a27408bcfa2ed8617011e2e9 154 Pfam PF17384 RimP C-terminal SH3 domain 89 154 2.9E-22 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal WM46_RS05275 1f4f8c602018a52d97d646ba488ba5cf 187 SMART SM00421 114 171 1.9E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05275 1f4f8c602018a52d97d646ba488ba5cf 187 Pfam PF00196 Bacterial regulatory proteins, luxR family 116 169 9.7E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS05275 1f4f8c602018a52d97d646ba488ba5cf 187 Gene3D G3DSA:1.10.10.10 2 176 6.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05275 1f4f8c602018a52d97d646ba488ba5cf 187 SUPERFAMILY SSF46894 107 171 4.08E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 1 416 41.415 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 PIRSF PIRSF000151 1 417 1.9E-176 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 Gene3D G3DSA:3.40.605.10 2 237 6.7E-43 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 Gene3D G3DSA:3.40.605.10 238 417 2.8E-38 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 Pfam PF00171 Aldehyde dehydrogenase family 8 282 6.7E-16 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 9 406 1.1E-194 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 323 344 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 WM46_RS13645 421f4e94bc687c7cf35ad014f6514851 417 SUPERFAMILY SSF53720 3 415 7.59E-115 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 Pfam PF00664 ABC transporter transmembrane region 27 297 2.4E-60 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 Gene3D G3DSA:1.20.1560.10 1 328 4.9E-66 T 28-03-2018 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 SUPERFAMILY SSF90123 8 325 7.72E-75 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 12 581 3.4E-272 T 28-03-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 Pfam PF00005 ABC transporter 359 509 2.1E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 SUPERFAMILY SSF52540 332 580 1.36E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 Gene3D G3DSA:3.40.50.300 329 582 8.2E-79 T 28-03-2018 WM46_RS09835 6d83950c2f309ade146fc60d320fac9f 582 SMART SM00382 368 555 1.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS12725 5edcdeff3033b662b95b1057dbc59263 231 Pfam PF09339 IclR helix-turn-helix domain 10 60 5.9E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS12725 5edcdeff3033b662b95b1057dbc59263 231 Gene3D G3DSA:1.10.10.10 12 74 3.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12725 5edcdeff3033b662b95b1057dbc59263 231 Gene3D G3DSA:3.30.450.40 75 228 8.0E-13 T 28-03-2018 IPR029016 GAF domain-like WM46_RS12725 5edcdeff3033b662b95b1057dbc59263 231 SUPERFAMILY SSF46785 8 75 3.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12725 5edcdeff3033b662b95b1057dbc59263 231 SUPERFAMILY SSF55781 65 227 6.38E-14 T 28-03-2018 IPR029016 GAF domain-like WM46_RS12725 5edcdeff3033b662b95b1057dbc59263 231 SMART SM00346 8 90 0.0029 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS14080 89fb28431e79cda1980ec1c5fdd99e67 176 SUPERFAMILY SSF55144 5 174 2.07E-45 T 28-03-2018 IPR009097 Cyclic phosphodiesterase WM46_RS14080 89fb28431e79cda1980ec1c5fdd99e67 176 Pfam PF02834 LigT like Phosphoesterase 93 166 9.1E-7 T 28-03-2018 IPR014051 Phosphoesterase, HXTX WM46_RS14080 89fb28431e79cda1980ec1c5fdd99e67 176 Pfam PF02834 LigT like Phosphoesterase 11 89 1.8E-13 T 28-03-2018 IPR014051 Phosphoesterase, HXTX WM46_RS14080 89fb28431e79cda1980ec1c5fdd99e67 176 Gene3D G3DSA:3.90.1140.10 1 176 8.3E-31 T 28-03-2018 WM46_RS14080 89fb28431e79cda1980ec1c5fdd99e67 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 6 174 2.2E-40 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 WM46_RS14080 89fb28431e79cda1980ec1c5fdd99e67 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 174 21.876 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 WM46_RS03475 a0c5ac0d42da7051a064df774debb942 163 TIGRFAM TIGR04493 microcomp_PduM: microcompartment protein PduM 7 159 3.0E-62 T 28-03-2018 IPR030992 Microcompartment protein PduM GO:0005198 WM46_RS03475 a0c5ac0d42da7051a064df774debb942 163 Pfam PF15953 Putative propanediol utilisation 7 158 2.6E-54 T 28-03-2018 IPR030992 Microcompartment protein PduM GO:0005198 WM46_RS08555 4deda265aee755bf1e9ce48232a21020 399 Gene3D G3DSA:1.10.3720.10 4 383 1.1E-5 T 28-03-2018 WM46_RS08555 4deda265aee755bf1e9ce48232a21020 399 Pfam PF02687 FtsX-like permease family 296 392 3.5E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS08555 4deda265aee755bf1e9ce48232a21020 399 Pfam PF12704 MacB-like periplasmic core domain 27 208 1.6E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS08555 4deda265aee755bf1e9ce48232a21020 399 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 399 1.2E-145 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 WM46_RS22470 abe54d6337f8c90ae42e27d9725abcfb 573 Gene3D G3DSA:1.25.40.10 453 560 8.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS11530 cf5cdb30008d9643988592be34623fb5 142 PRINTS PR01438 Universal stress protein signature 120 142 2.4E-14 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS11530 cf5cdb30008d9643988592be34623fb5 142 PRINTS PR01438 Universal stress protein signature 103 115 2.4E-14 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS11530 cf5cdb30008d9643988592be34623fb5 142 PRINTS PR01438 Universal stress protein signature 2 20 2.4E-14 T 28-03-2018 IPR006015 Universal stress protein A WM46_RS11530 cf5cdb30008d9643988592be34623fb5 142 SUPERFAMILY SSF52402 1 142 5.02E-26 T 28-03-2018 WM46_RS11530 cf5cdb30008d9643988592be34623fb5 142 Gene3D G3DSA:3.40.50.620 2 142 9.8E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11530 cf5cdb30008d9643988592be34623fb5 142 Pfam PF00582 Universal stress protein family 1 142 1.0E-24 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS02600 d3b6a6eaa2cb2b81ca915f472fbb2444 243 SMART SM00422 4 73 4.5E-29 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS02600 d3b6a6eaa2cb2b81ca915f472fbb2444 243 Pfam PF13411 MerR HTH family regulatory protein 4 72 2.9E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS02600 d3b6a6eaa2cb2b81ca915f472fbb2444 243 Gene3D G3DSA:1.10.1660.10 1 139 2.9E-25 T 28-03-2018 WM46_RS02600 d3b6a6eaa2cb2b81ca915f472fbb2444 243 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 30 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS02600 d3b6a6eaa2cb2b81ca915f472fbb2444 243 SUPERFAMILY SSF46955 3 92 1.01E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS24830 bc389e9199e1a6520758ec5abdfcb795 398 Gene3D G3DSA:1.20.1250.20 202 398 0.0014 T 28-03-2018 WM46_RS24830 bc389e9199e1a6520758ec5abdfcb795 398 Hamap MF_01585 Lysophospholipid transporter LplT [lplT]. 1 397 39.474 T 28-03-2018 IPR023727 Lysophospholipid transporter LplT GO:0005886|GO:0051977|GO:0051978 WM46_RS24830 bc389e9199e1a6520758ec5abdfcb795 398 Gene3D G3DSA:1.20.1250.20 3 194 1.5E-14 T 28-03-2018 WM46_RS24830 bc389e9199e1a6520758ec5abdfcb795 398 SUPERFAMILY SSF103473 16 396 3.53E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS24830 bc389e9199e1a6520758ec5abdfcb795 398 Pfam PF07690 Major Facilitator Superfamily 20 349 4.1E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS04245 c5c73948e87a4319c04ed13d4bfa07ab 189 SUPERFAMILY SSF54593 2 186 3.09E-68 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS04245 c5c73948e87a4319c04ed13d4bfa07ab 189 Gene3D G3DSA:3.10.180.10 7 186 2.8E-77 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS04245 c5c73948e87a4319c04ed13d4bfa07ab 189 Pfam PF06185 YecM protein 10 185 5.1E-70 T 28-03-2018 IPR010393 Protein of unknown function DUF991 WM46_RS19545 9e2feeb67c18469fe6ea3ae0630eb051 346 Pfam PF12849 PBP superfamily domain 25 307 3.2E-63 T 28-03-2018 IPR024370 PBP domain WM46_RS19545 9e2feeb67c18469fe6ea3ae0630eb051 346 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 29 335 1.2E-128 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 WM46_RS19545 9e2feeb67c18469fe6ea3ae0630eb051 346 Gene3D G3DSA:3.40.190.10 161 337 8.9E-27 T 28-03-2018 WM46_RS19545 9e2feeb67c18469fe6ea3ae0630eb051 346 Gene3D G3DSA:3.40.190.10 26 160 3.4E-31 T 28-03-2018 WM46_RS19545 9e2feeb67c18469fe6ea3ae0630eb051 346 PIRSF PIRSF002756 1 338 6.9E-107 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 WM46_RS19545 9e2feeb67c18469fe6ea3ae0630eb051 346 SUPERFAMILY SSF53850 28 338 3.47E-98 T 28-03-2018 WM46_RS24770 deeb060dd546dd0c2df9951efec08495 278 Gene3D G3DSA:2.60.120.10 132 278 5.7E-54 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS24770 deeb060dd546dd0c2df9951efec08495 278 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 278 56.97 T 28-03-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 WM46_RS24770 deeb060dd546dd0c2df9951efec08495 278 Pfam PF04962 KduI/IolB family 32 273 7.1E-42 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 WM46_RS24770 deeb060dd546dd0c2df9951efec08495 278 Gene3D G3DSA:2.60.120.520 24 131 1.8E-52 T 28-03-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 WM46_RS24770 deeb060dd546dd0c2df9951efec08495 278 PIRSF PIRSF006625 1 278 7.1E-135 T 28-03-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 WM46_RS24770 deeb060dd546dd0c2df9951efec08495 278 SUPERFAMILY SSF51182 2 262 1.22E-109 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS03645 9d3189c16b5953e88f97e0c5522ba620 310 Gene3D G3DSA:3.10.350.10 40 87 0.0013 T 28-03-2018 WM46_RS03645 9d3189c16b5953e88f97e0c5522ba620 310 Pfam PF03734 L,D-transpeptidase catalytic domain 98 231 2.3E-18 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 WM46_RS03645 9d3189c16b5953e88f97e0c5522ba620 310 Gene3D G3DSA:2.40.440.10 92 233 3.1E-30 T 28-03-2018 WM46_RS03645 9d3189c16b5953e88f97e0c5522ba620 310 SUPERFAMILY SSF141523 175 232 1.01E-27 T 28-03-2018 WM46_RS03645 9d3189c16b5953e88f97e0c5522ba620 310 SUPERFAMILY SSF141523 96 147 1.01E-27 T 28-03-2018 WM46_RS01890 c96e0aeb251f673d0e66e837e011e742 551 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 10 237 2.2E-51 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 WM46_RS01890 c96e0aeb251f673d0e66e837e011e742 551 Hamap MF_01165 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase [arnT]. 1 551 42.529 T 28-03-2018 IPR022839 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase GO:0016763 WM46_RS21225 ae0873029b0486221d34a1983f9871df 66 Gene3D G3DSA:3.10.20.30 1 66 3.6E-19 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS21225 ae0873029b0486221d34a1983f9871df 66 SUPERFAMILY SSF54285 1 66 7.85E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp WM46_RS21225 ae0873029b0486221d34a1983f9871df 66 Pfam PF02597 ThiS family 3 66 9.2E-13 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 WM46_RS21225 ae0873029b0486221d34a1983f9871df 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 1.9E-18 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis WM46_RS06250 d060b79b59369ad61b7566369cb71634 398 SUPERFAMILY SSF103473 15 389 1.57E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06250 d060b79b59369ad61b7566369cb71634 398 Pfam PF07690 Major Facilitator Superfamily 22 344 3.2E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS06250 d060b79b59369ad61b7566369cb71634 398 Gene3D G3DSA:1.20.1250.20 4 196 2.4E-12 T 28-03-2018 WM46_RS06250 d060b79b59369ad61b7566369cb71634 398 Gene3D G3DSA:1.20.1250.20 202 397 9.2E-20 T 28-03-2018 WM46_RS03200 cfb7f00922df009454150ce730e5f0eb 271 SUPERFAMILY SSF57938 167 217 4.45E-6 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 WM46_RS03200 cfb7f00922df009454150ce730e5f0eb 271 Pfam PF03589 Antitermination protein 23 109 4.7E-26 T 28-03-2018 IPR003222 Antitermination protein GO:0003677|GO:0006355 WM46_RS03200 cfb7f00922df009454150ce730e5f0eb 271 Pfam PF03589 Antitermination protein 176 262 1.1E-23 T 28-03-2018 IPR003222 Antitermination protein GO:0003677|GO:0006355 WM46_RS03200 cfb7f00922df009454150ce730e5f0eb 271 Gene3D G3DSA:2.10.230.10 91 188 1.4E-10 T 28-03-2018 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 Gene3D G3DSA:1.10.287.70 573 640 1.2E-17 T 28-03-2018 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 SUPERFAMILY SSF81442 43 560 2.49E-180 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 4.1E-94 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 28-03-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 Gene3D G3DSA:1.20.210.10 43 561 1.6E-186 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12670 2bf380eba278fe23a2ab84e0a84cb2bf 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 503 6.0E-136 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS09630 42cfcd325b2610619ce4dff1f624e1d6 720 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 8 705 0.0 T 28-03-2018 IPR010020 Integral membrane protein, YccS/YhfK WM46_RS09630 42cfcd325b2610619ce4dff1f624e1d6 720 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 8 706 0.0 T 28-03-2018 IPR010019 Integral membrane protein, YccS WM46_RS09630 42cfcd325b2610619ce4dff1f624e1d6 720 Pfam PF13515 Fusaric acid resistance protein-like 405 525 1.1E-24 T 28-03-2018 WM46_RS09630 42cfcd325b2610619ce4dff1f624e1d6 720 Pfam PF12805 FUSC-like inner membrane protein yccS 66 345 6.2E-111 T 28-03-2018 IPR032692 Integral membrane protein YccS, N-terminal WM46_RS14995 f6404bb3ea5b2c74fefdfc9c3a040d9c 147 SUPERFAMILY SSF55804 1 145 1.83E-32 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS14995 f6404bb3ea5b2c74fefdfc9c3a040d9c 147 Gene3D G3DSA:3.40.930.10 1 147 5.1E-30 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS14995 f6404bb3ea5b2c74fefdfc9c3a040d9c 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 145 3.1E-29 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS15585 a9f75e520d91a27c2756802cf5a73da7 454 SUPERFAMILY SSF56954 4 452 7.72E-66 T 28-03-2018 WM46_RS15585 a9f75e520d91a27c2756802cf5a73da7 454 Gene3D G3DSA:1.20.1600.10 23 453 8.6E-59 T 28-03-2018 WM46_RS15585 a9f75e520d91a27c2756802cf5a73da7 454 Pfam PF02321 Outer membrane efflux protein 274 451 1.4E-17 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS15585 a9f75e520d91a27c2756802cf5a73da7 454 Pfam PF02321 Outer membrane efflux protein 65 245 6.9E-13 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS13385 0cc4a1a1289f4fbea30020922e818bc3 170 SMART SM00903 14 161 1.1E-41 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 WM46_RS13385 0cc4a1a1289f4fbea30020922e818bc3 170 TIGRFAM TIGR02296 HpaC: 4-hydroxyphenylacetate 3-monooxygenase, reductase component 10 163 1.1E-77 T 28-03-2018 IPR011982 4-hydroxyphenylacetate 3-monooxygenase, reductase component GO:0016651|GO:0042537|GO:0051287|GO:0055114 KEGG: 00740+1.5.1.36 WM46_RS13385 0cc4a1a1289f4fbea30020922e818bc3 170 Pfam PF01613 Flavin reductase like domain 14 162 2.3E-25 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 WM46_RS13385 0cc4a1a1289f4fbea30020922e818bc3 170 SUPERFAMILY SSF50475 9 162 6.38E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS13385 0cc4a1a1289f4fbea30020922e818bc3 170 Gene3D G3DSA:2.30.110.10 4 162 6.0E-33 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS14980 225ea6305a1290344fa457c73c29b942 323 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 321 1.3E-119 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 WM46_RS14980 225ea6305a1290344fa457c73c29b942 323 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 322 1.4E-165 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 WM46_RS14980 225ea6305a1290344fa457c73c29b942 323 SUPERFAMILY SSF56655 3 322 4.3E-98 T 28-03-2018 WM46_RS14980 225ea6305a1290344fa457c73c29b942 323 Gene3D G3DSA:3.30.540.10 151 323 1.5E-37 T 28-03-2018 WM46_RS14980 225ea6305a1290344fa457c73c29b942 323 Gene3D G3DSA:3.30.540.10 1 148 1.2E-49 T 28-03-2018 WM46_RS14980 225ea6305a1290344fa457c73c29b942 323 PIRSF PIRSF004532 1 323 1.3E-131 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.7E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 Gene3D G3DSA:3.40.190.10 179 255 6.6E-13 T 28-03-2018 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 Gene3D G3DSA:3.40.190.10 89 178 2.3E-20 T 28-03-2018 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 Gene3D G3DSA:1.10.10.10 1 88 8.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 SUPERFAMILY SSF46785 2 86 8.84E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 Pfam PF03466 LysR substrate binding domain 89 283 8.4E-38 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS05100 467e73c99dc51d48b9d84229428e15df 286 SUPERFAMILY SSF53850 90 284 3.26E-37 T 28-03-2018 WM46_RS08620 4d98ce84b644edf6b3a78ceca3484b2f 210 Hamap MF_01889 Penicillin-binding protein activator LpoB [lpoB]. 1 208 34.155 T 28-03-2018 IPR014094 Penicillin-binding protein activator LpoB WM46_RS08620 4d98ce84b644edf6b3a78ceca3484b2f 210 Gene3D G3DSA:3.40.50.10070 92 210 1.2E-12 T 28-03-2018 WM46_RS08620 4d98ce84b644edf6b3a78ceca3484b2f 210 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 3 209 1.2E-60 T 28-03-2018 IPR014094 Penicillin-binding protein activator LpoB WM46_RS08620 4d98ce84b644edf6b3a78ceca3484b2f 210 Pfam PF13036 Peptidoglycan-synthase activator LpoB 71 206 2.6E-37 T 28-03-2018 IPR014094 Penicillin-binding protein activator LpoB WM46_RS02180 b1f972779be2db9ee0256c93dbf076e5 70 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 12 58 1.8E-20 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 WM46_RS02180 b1f972779be2db9ee0256c93dbf076e5 70 Pfam PF04995 Heme exporter protein D (CcmD) 15 58 1.7E-17 T 28-03-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 WM46_RS11455 45a66beba6b28b4b6981c820c715566c 461 TIGRFAM TIGR00771 DcuC: transporter, anaerobic C4-dicarboxylate uptake C (DcuC) family 58 441 3.0E-190 T 28-03-2018 IPR004669 C4-dicarboxylate anaerobic carrier GO:0015556|GO:0015740|GO:0016021 WM46_RS11455 45a66beba6b28b4b6981c820c715566c 461 Pfam PF03606 C4-dicarboxylate anaerobic carrier 6 451 6.0E-134 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 Gene3D G3DSA:3.20.20.120 141 413 3.4E-48 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 SUPERFAMILY SSF54826 8 137 2.12E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 SUPERFAMILY SSF51604 139 415 3.54E-81 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 TIGRFAM TIGR03247 glucar-dehydr: glucarate dehydratase 6 446 6.3E-271 T 28-03-2018 IPR017653 Glucarate dehydratase GO:0000287|GO:0008872|GO:0019394 KEGG: 00053+4.2.1.40|MetaCyc: PWY-6499 WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 SMART SM00922 185 285 1.8E-15 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 Pfam PF13378 Enolase C-terminal domain-like 189 405 8.0E-37 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS25095 c710258265dab70ad72033b0068c3f1b 446 Gene3D G3DSA:3.30.390.10 1 140 5.8E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Hamap MF_01314 Anaerobic nitric oxide reductase transcription regulator NorR [norR]. 1 504 62.823 T 28-03-2018 IPR023944 Anaerobic nitric oxide reductase transcription regulator GO:0003700|GO:0006355 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 273 288 - T 28-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 211 224 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 400 409 - T 28-03-2018 IPR025944 Sigma-54 interaction domain, conserved site WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Gene3D G3DSA:1.10.8.60 360 436 2.8E-20 T 28-03-2018 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Pfam PF01590 GAF domain 23 154 1.6E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 SMART SM00065 20 167 4.6E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Gene3D G3DSA:3.40.50.300 182 359 1.6E-26 T 28-03-2018 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 SMART SM00382 207 350 2.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 SUPERFAMILY SSF55781 22 170 5.89E-17 T 28-03-2018 IPR029016 GAF domain-like WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Gene3D G3DSA:1.10.10.60 437 505 1.2E-9 T 28-03-2018 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 SUPERFAMILY SSF52540 187 420 9.54E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Gene3D G3DSA:3.30.450.40 21 171 8.6E-17 T 28-03-2018 IPR029016 GAF domain-like WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 SUPERFAMILY SSF46689 452 503 5.82E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS25470 01ee0b3d8bbd908d4349ed3f94bf6f00 505 Pfam PF00158 Sigma-54 interaction domain 187 353 1.3E-66 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 WM46_RS15700 3884d4cfec69bb47fc67aa47073454eb 415 Pfam PF00589 Phage integrase family 207 382 1.9E-16 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS15700 3884d4cfec69bb47fc67aa47073454eb 415 Gene3D G3DSA:1.10.443.10 201 392 3.7E-19 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS15700 3884d4cfec69bb47fc67aa47073454eb 415 Pfam PF13356 Arm DNA-binding domain 3 86 7.8E-20 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS15700 3884d4cfec69bb47fc67aa47073454eb 415 Gene3D G3DSA:1.10.150.130 88 200 6.5E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS15700 3884d4cfec69bb47fc67aa47073454eb 415 SUPERFAMILY SSF56349 97 386 2.59E-45 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS11300 32bb9ebb1bdfe5a0b61d9c8ea257e9cc 361 SUPERFAMILY SSF52540 130 331 1.3E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS11300 32bb9ebb1bdfe5a0b61d9c8ea257e9cc 361 Gene3D G3DSA:3.40.50.300 127 337 6.1E-28 T 28-03-2018 WM46_RS11300 32bb9ebb1bdfe5a0b61d9c8ea257e9cc 361 Pfam PF02562 PhoH-like protein 131 334 2.7E-95 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 Pfam PF13476 AAA domain 5 206 5.8E-29 T 28-03-2018 WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 SUPERFAMILY SSF52540 1 182 9.06E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 SUPERFAMILY SSF52540 215 251 9.06E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 SUPERFAMILY SSF52540 834 1034 9.06E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 Gene3D G3DSA:3.40.50.300 802 1033 9.4E-15 T 28-03-2018 WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 SUPERFAMILY SSF52540 292 401 1.73E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 SUPERFAMILY SSF52540 20 57 1.73E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 Gene3D G3DSA:3.40.50.300 1 246 2.3E-34 T 28-03-2018 WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 Pfam PF13558 Putative exonuclease SbcCD, C subunit 930 1001 4.8E-15 T 28-03-2018 WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 TIGRFAM TIGR00618 sbcc: exonuclease SbcC 1 1039 0.0 T 28-03-2018 IPR004592 Nuclease SbcC, gammaproteobacteria type WM46_RS12925 3db7f5c4b14a1b3a8a9560990f058001 1047 Gene3D G3DSA:1.20.1170.10 511 766 2.0E-4 T 28-03-2018 WM46_RS03850 4ca4ee3efc9bece1563dc48411e56dfd 401 Pfam PF04143 Sulphur transport 3 160 1.7E-25 T 28-03-2018 IPR007272 Sulphur transport domain WM46_RS03850 4ca4ee3efc9bece1563dc48411e56dfd 401 Pfam PF04143 Sulphur transport 237 386 8.7E-23 T 28-03-2018 IPR007272 Sulphur transport domain WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 SUPERFAMILY SSF88659 199 283 1.18E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 Pfam PF04542 Sigma-70 region 2 53 122 1.4E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 Gene3D G3DSA:1.10.601.10 10 122 4.3E-32 T 28-03-2018 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 Gene3D G3DSA:1.10.10.10 222 284 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 48 281 2.1E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 PIRSF PIRSF000770 5 284 1.1E-32 T 28-03-2018 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 PRINTS PR00046 Major sigma-70 factor signature 77 90 4.9E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 PRINTS PR00046 Major sigma-70 factor signature 232 244 4.9E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 4.9E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 4.9E-19 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 14 283 1.2E-129 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 54.953 T 28-03-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 Pfam PF04545 Sigma-70, region 4 228 280 1.1E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS18160 cf0806f6499842597cecb0396d02e7d6 284 SUPERFAMILY SSF88946 15 122 1.13E-37 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 WM46_RS17155 2110f14ec426ff041593fc2a902cc46c 197 Hamap MF_00528 Septum formation protein Maf [maf]. 3 189 32.437 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS17155 2110f14ec426ff041593fc2a902cc46c 197 Pfam PF02545 Maf-like protein 4 184 3.0E-58 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS17155 2110f14ec426ff041593fc2a902cc46c 197 Gene3D G3DSA:3.90.950.10 1 188 6.1E-70 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS17155 2110f14ec426ff041593fc2a902cc46c 197 PIRSF PIRSF006305 1 191 1.9E-54 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS17155 2110f14ec426ff041593fc2a902cc46c 197 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 182 7.2E-71 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 WM46_RS17155 2110f14ec426ff041593fc2a902cc46c 197 SUPERFAMILY SSF52972 2 184 1.7E-62 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like WM46_RS01495 3880a6b04af3d2fe7410664dd8e1d2f1 183 Hamap MF_01042 UPF0115 protein YfcN [yfcN]. 1 174 42.473 T 28-03-2018 IPR022990 Uncharacterised protein family UPF0115 WM46_RS01495 3880a6b04af3d2fe7410664dd8e1d2f1 183 SMART SM00463 95 173 1.4E-21 T 28-03-2018 IPR002625 Smr domain WM46_RS01495 3880a6b04af3d2fe7410664dd8e1d2f1 183 SUPERFAMILY SSF160443 96 170 1.31E-9 T 28-03-2018 IPR002625 Smr domain WM46_RS01495 3880a6b04af3d2fe7410664dd8e1d2f1 183 Pfam PF01713 Smr domain 98 172 7.7E-18 T 28-03-2018 IPR002625 Smr domain WM46_RS00260 d896dce126cfe7895debdd3c1186dd61 245 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 5 243 9.8E-89 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD WM46_RS00260 d896dce126cfe7895debdd3c1186dd61 245 SUPERFAMILY SSF48452 27 121 2.47E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS00260 d896dce126cfe7895debdd3c1186dd61 245 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 4 242 39.486 T 28-03-2018 IPR017689 Outer membrane protein assembly factor BamD WM46_RS00260 d896dce126cfe7895debdd3c1186dd61 245 Gene3D G3DSA:1.25.20.10 30 240 3.0E-15 T 28-03-2018 WM46_RS00260 d896dce126cfe7895debdd3c1186dd61 245 Pfam PF13525 Outer membrane lipoprotein 28 236 5.5E-86 T 28-03-2018 WM46_RS01950 a2da1b012ea2032627612abccf31221c 267 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 19 244 1.3E-65 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 WM46_RS01950 a2da1b012ea2032627612abccf31221c 267 SUPERFAMILY SSF51621 4 255 2.74E-80 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS01950 a2da1b012ea2032627612abccf31221c 267 Gene3D G3DSA:3.20.20.60 1 267 2.2E-56 T 28-03-2018 WM46_RS01950 a2da1b012ea2032627612abccf31221c 267 Hamap MF_01290 2-keto-3-deoxy-L-rhamnonate aldolase [rhmA]. 1 267 68.468 T 28-03-2018 IPR023593 2-keto-3-deoxy-L-rhamnonate aldolase GO:0016832 KEGG: 00051+4.1.2.53|MetaCyc: PWY-6713 WM46_RS19985 3561e33b6095e84c1ffab1ed2d502fc2 361 Gene3D G3DSA:2.60.40.1090 224 361 1.5E-29 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS19985 3561e33b6095e84c1ffab1ed2d502fc2 361 Pfam PF00419 Fimbrial protein 220 360 1.7E-12 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS19985 3561e33b6095e84c1ffab1ed2d502fc2 361 SUPERFAMILY SSF49401 224 360 3.08E-25 T 28-03-2018 IPR008966 Adhesion domain WM46_RS16650 c4c97623dbdf493355c8d3927896349f 239 SUPERFAMILY SSF100950 5 233 2.09E-59 T 28-03-2018 WM46_RS16650 c4c97623dbdf493355c8d3927896349f 239 Gene3D G3DSA:3.40.50.1360 1 237 1.5E-49 T 28-03-2018 WM46_RS16650 c4c97623dbdf493355c8d3927896349f 239 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 28-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 WM46_RS16650 c4c97623dbdf493355c8d3927896349f 239 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 225 2.2E-19 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 WM46_RS12755 ae7ed75faba87b6993d2e76df21e5264 171 Gene3D G3DSA:1.10.3760.10 50 167 5.2E-38 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 WM46_RS12755 ae7ed75faba87b6993d2e76df21e5264 171 PIRSF PIRSF006162 11 169 2.8E-57 T 28-03-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 WM46_RS12755 ae7ed75faba87b6993d2e76df21e5264 171 SUPERFAMILY SSF101307 16 162 2.22E-47 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 WM46_RS12755 ae7ed75faba87b6993d2e76df21e5264 171 Pfam PF04608 Phosphatidylglycerophosphatase A 22 162 8.3E-52 T 28-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 Gene3D G3DSA:1.10.10.10 1 84 9.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 Gene3D G3DSA:3.40.190.10 86 176 1.2E-24 T 28-03-2018 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 SUPERFAMILY SSF53850 88 286 1.74E-47 T 28-03-2018 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 Gene3D G3DSA:3.40.190.10 177 261 1.7E-20 T 28-03-2018 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 Pfam PF03466 LysR substrate binding domain 86 286 1.2E-50 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS02415 a46433774a21f22a76b51d7d07e2579c 287 SUPERFAMILY SSF46785 2 109 2.23E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16115 77ce02d7d853a86f2896a3eb449f1bea 275 Pfam PF00149 Calcineurin-like phosphoesterase 16 206 5.0E-22 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS16115 77ce02d7d853a86f2896a3eb449f1bea 275 Gene3D G3DSA:3.60.21.10 8 272 2.5E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS16115 77ce02d7d853a86f2896a3eb449f1bea 275 SUPERFAMILY SSF56300 16 266 5.49E-61 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS16115 77ce02d7d853a86f2896a3eb449f1bea 275 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 206 261 9.0E-23 T 28-03-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 WM46_RS16115 77ce02d7d853a86f2896a3eb449f1bea 275 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 15 261 40.968 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 WM46_RS07230 8405cff5ad1a35f9ce2064e288a914ba 204 PIRSF PIRSF004690 2 204 8.2E-64 T 28-03-2018 IPR026269 Tat proofreading chaperone DmsD-type WM46_RS07230 8405cff5ad1a35f9ce2064e288a914ba 204 SUPERFAMILY SSF89155 4 202 1.03E-56 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS07230 8405cff5ad1a35f9ce2064e288a914ba 204 Pfam PF02613 Nitrate reductase delta subunit 42 163 1.2E-22 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS07230 8405cff5ad1a35f9ce2064e288a914ba 204 Hamap MF_00940 Tat proofreading chaperone DmsD [dmsD]. 5 204 42.052 T 28-03-2018 IPR028611 Tat proofreading chaperone DmsD GO:0005048 WM46_RS07230 8405cff5ad1a35f9ce2064e288a914ba 204 Gene3D G3DSA:1.10.3480.10 1 204 1.1E-54 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone WM46_RS23120 04a88ffc9d51f744b8724e791bc5c844 212 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 43 205 38.701 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM46_RS23120 04a88ffc9d51f744b8724e791bc5c844 212 Gene3D G3DSA:3.30.1060.10 26 204 2.6E-79 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM46_RS23120 04a88ffc9d51f744b8724e791bc5c844 212 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 45 199 2.0E-71 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM46_RS23120 04a88ffc9d51f744b8724e791bc5c844 212 Pfam PF01625 Peptide methionine sulfoxide reductase 46 199 2.1E-67 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM46_RS23120 04a88ffc9d51f744b8724e791bc5c844 212 SUPERFAMILY SSF55068 5 208 6.93E-85 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 210 3.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 194 3.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 222 3.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 Gene3D G3DSA:1.10.10.10 165 240 1.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 SMART SM00421 177 234 1.4E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 179 234 4.0E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 SUPERFAMILY SSF75516 8 170 6.41E-37 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 Pfam PF03472 Autoinducer binding domain 23 158 1.7E-34 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 SUPERFAMILY SSF46894 164 240 2.86E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 ProSitePatterns PS00622 LuxR-type HTH domain signature. 194 221 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS03915 a392d5da71eca8212d3c19ef0caf535c 240 Gene3D G3DSA:3.30.450.80 1 164 7.9E-43 T 28-03-2018 WM46_RS14780 ab713190db92609f4c3c8e0fe06d1851 195 Pfam PF00994 Probable molybdopterin binding domain 8 147 6.0E-28 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS14780 ab713190db92609f4c3c8e0fe06d1851 195 SUPERFAMILY SSF53218 3 188 9.42E-48 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS14780 ab713190db92609f4c3c8e0fe06d1851 195 SMART SM00852 7 153 2.8E-21 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS14780 ab713190db92609f4c3c8e0fe06d1851 195 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 69 82 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 WM46_RS14780 ab713190db92609f4c3c8e0fe06d1851 195 Gene3D G3DSA:3.40.980.10 1 188 7.7E-40 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS14780 ab713190db92609f4c3c8e0fe06d1851 195 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 4 146 8.7E-40 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS14690 1ee3f1deecd42b3dee25798bfde9f5bf 149 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 141 1.3E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM46_RS14690 1ee3f1deecd42b3dee25798bfde9f5bf 149 Gene3D G3DSA:3.10.50.40 2 149 1.2E-20 T 28-03-2018 WM46_RS14690 1ee3f1deecd42b3dee25798bfde9f5bf 149 SUPERFAMILY SSF54534 5 143 2.36E-35 T 28-03-2018 WM46_RS18580 b81229aebe628ed0a526712146f56438 328 SUPERFAMILY SSF53822 23 324 3.34E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS18580 b81229aebe628ed0a526712146f56438 328 Gene3D G3DSA:3.40.50.2300 142 297 3.6E-19 T 28-03-2018 WM46_RS18580 b81229aebe628ed0a526712146f56438 328 Gene3D G3DSA:3.40.50.2300 22 141 7.5E-20 T 28-03-2018 WM46_RS18580 b81229aebe628ed0a526712146f56438 328 Pfam PF13407 Periplasmic binding protein domain 26 285 1.4E-60 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS18580 b81229aebe628ed0a526712146f56438 328 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 26 326 8.0E-135 T 28-03-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 WM46_RS01910 3c86c435e869dc821bc4e4024085b27f 379 Gene3D G3DSA:3.90.1150.10 246 379 3.2E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS01910 3c86c435e869dc821bc4e4024085b27f 379 Gene3D G3DSA:3.40.640.10 3 245 7.0E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS01910 3c86c435e869dc821bc4e4024085b27f 379 SUPERFAMILY SSF53383 4 376 1.34E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS01910 3c86c435e869dc821bc4e4024085b27f 379 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 374 4.0E-133 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS01910 3c86c435e869dc821bc4e4024085b27f 379 PIRSF PIRSF000390 1 379 7.4E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS01910 3c86c435e869dc821bc4e4024085b27f 379 Hamap MF_01167 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase [arnB]. 1 379 68.652 T 28-03-2018 IPR022850 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase, ArnB GO:0008483 KEGG: 00520+2.6.1.87 WM46_RS18440 d72c1ad742cce2952fc19bb1a9da437b 336 PIRSF PIRSF004532 1 333 9.7E-143 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 WM46_RS18440 d72c1ad742cce2952fc19bb1a9da437b 336 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 334 4.5E-184 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 WM46_RS18440 d72c1ad742cce2952fc19bb1a9da437b 336 Gene3D G3DSA:3.30.540.10 152 336 7.7E-55 T 28-03-2018 WM46_RS18440 d72c1ad742cce2952fc19bb1a9da437b 336 Gene3D G3DSA:3.30.540.10 1 146 1.2E-59 T 28-03-2018 WM46_RS18440 d72c1ad742cce2952fc19bb1a9da437b 336 SUPERFAMILY SSF56655 2 325 1.22E-112 T 28-03-2018 WM46_RS18440 d72c1ad742cce2952fc19bb1a9da437b 336 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 322 2.9E-133 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 SMART SM01235 16 155 9.6E-55 T 28-03-2018 IPR025992 Haem-binding domain WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 Pfam PF14376 Haem-binding domain 18 152 1.9E-35 T 28-03-2018 IPR025992 Haem-binding domain WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 Pfam PF03150 Di-haem cytochrome c peroxidase 185 332 3.4E-46 T 28-03-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 Gene3D G3DSA:1.10.760.10 28 158 0.012 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 Gene3D G3DSA:1.10.760.10 336 462 5.9E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 Gene3D G3DSA:1.10.760.10 173 335 4.0E-41 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 SUPERFAMILY SSF46626 321 460 1.43E-38 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 SUPERFAMILY SSF46626 169 320 6.86E-46 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS20760 52dbe3d5619e2e9e05fe2676be1bc310 464 Pfam PF00034 Cytochrome c 340 453 4.5E-7 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 WM46_RS13530 363e7a50ae6b4d4d13693813fb2d8809 119 Pfam PF13876 Phage protein (N4 Gp49/phage Sf6 gene 66) family 20 115 1.3E-34 T 28-03-2018 IPR025915 Phage protein (N4 Gp49/phage Sf6 gene 66) family WM46_RS06890 e1e77d16bc74db49f6cbdb8c945975e1 370 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 3 256 3.1E-74 T 28-03-2018 IPR018712 Domain of unknown function DUF2235 WM46_RS06890 e1e77d16bc74db49f6cbdb8c945975e1 370 SUPERFAMILY SSF53474 5 119 7.36E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06890 e1e77d16bc74db49f6cbdb8c945975e1 370 Gene3D G3DSA:3.40.50.1820 3 358 1.1E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 Pfam PF01145 SPFH domain / Band 7 family 147 318 1.3E-21 T 28-03-2018 IPR001107 Band 7 domain WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 SMART SM00244 142 302 5.4E-16 T 28-03-2018 IPR001107 Band 7 domain WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 PRINTS PR00721 Stomatin signature 278 296 2.1E-18 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 PRINTS PR00721 Stomatin signature 297 318 2.1E-18 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 PRINTS PR00721 Stomatin signature 234 251 2.1E-18 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 PRINTS PR00721 Stomatin signature 254 277 2.1E-18 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 PRINTS PR00721 Stomatin signature 199 220 2.1E-18 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 PRINTS PR00721 Stomatin signature 322 345 2.1E-18 T 28-03-2018 IPR001972 Stomatin family GO:0016020 WM46_RS21480 5f4c1fefa1c163563542135ad15be1d0 375 SUPERFAMILY SSF117892 183 308 3.53E-27 T 28-03-2018 IPR001107 Band 7 domain WM46_RS12990 5792c3cf30ae01b4b2830371abcfa4b3 86 Hamap MF_01198 Anti-adapter protein IraP [iraP]. 1 86 28.256 T 28-03-2018 IPR019732 Sigma-S stabilisation anti-adaptor protein GO:0005737 WM46_RS12990 5792c3cf30ae01b4b2830371abcfa4b3 86 Pfam PF10796 Sigma-S stabilisation anti-adaptor protein 1 85 6.8E-30 T 28-03-2018 IPR019732 Sigma-S stabilisation anti-adaptor protein GO:0005737 WM46_RS00575 ae45535ac98643890b2673d6e6ce11e5 327 Gene3D G3DSA:3.40.50.2300 26 143 6.9E-20 T 28-03-2018 WM46_RS00575 ae45535ac98643890b2673d6e6ce11e5 327 SUPERFAMILY SSF53822 27 325 4.35E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS00575 ae45535ac98643890b2673d6e6ce11e5 327 Gene3D G3DSA:3.40.50.2300 144 299 3.0E-15 T 28-03-2018 WM46_RS00575 ae45535ac98643890b2673d6e6ce11e5 327 Pfam PF13407 Periplasmic binding protein domain 30 287 6.8E-55 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS08180 f36e50391c4a1942395abb31787171a7 447 Gene3D G3DSA:3.75.10.20 2 441 7.1E-218 T 28-03-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 WM46_RS08180 f36e50391c4a1942395abb31787171a7 447 SUPERFAMILY SSF55909 3 441 9.61E-203 T 28-03-2018 WM46_RS08180 f36e50391c4a1942395abb31787171a7 447 Pfam PF04996 Succinylarginine dihydrolase 3 440 6.5E-211 T 28-03-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 WM46_RS08180 f36e50391c4a1942395abb31787171a7 447 Hamap MF_01172 N-succinylarginine dihydrolase [astB]. 1 441 58.113 T 28-03-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 WM46_RS08180 f36e50391c4a1942395abb31787171a7 447 TIGRFAM TIGR03241 arg_catab_astB: succinylarginine dihydrolase 4 440 2.3E-235 T 28-03-2018 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23 WM46_RS00990 541fe20c5ff7ce1b909053a3f73173eb 279 SUPERFAMILY SSF53067 142 260 1.94E-20 T 28-03-2018 WM46_RS00990 541fe20c5ff7ce1b909053a3f73173eb 279 Gene3D G3DSA:3.30.420.150 145 259 1.2E-14 T 28-03-2018 WM46_RS00990 541fe20c5ff7ce1b909053a3f73173eb 279 Pfam PF14450 Cell division protein FtsA 142 247 7.2E-9 T 28-03-2018 WM46_RS00990 541fe20c5ff7ce1b909053a3f73173eb 279 SUPERFAMILY SSF53067 30 132 3.17E-10 T 28-03-2018 WM46_RS00990 541fe20c5ff7ce1b909053a3f73173eb 279 Gene3D G3DSA:3.30.420.40 6 144 8.2E-14 T 28-03-2018 WM46_RS00990 541fe20c5ff7ce1b909053a3f73173eb 279 TIGRFAM TIGR02529 EutJ: ethanolamine utilization protein EutJ family protein 34 267 6.6E-110 T 28-03-2018 IPR013366 Ethanolamine utilisation EutJ WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 Pfam PF00005 ABC transporter 40 196 1.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 SUPERFAMILY SSF52540 49 316 2.22E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 330 2.9E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 Gene3D G3DSA:3.40.50.300 16 335 3.4E-73 T 28-03-2018 WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 312 1.7E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS05760 8dc8226a01872f88f7d188a7c25d6c6d 337 SMART SM00382 48 254 4.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09565 856bd2bfd6d99cceff92dc9a310d62a2 146 Gene3D G3DSA:3.40.630.30 82 128 5.7E-10 T 28-03-2018 WM46_RS09565 856bd2bfd6d99cceff92dc9a310d62a2 146 SUPERFAMILY SSF55729 1 127 4.56E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS09565 856bd2bfd6d99cceff92dc9a310d62a2 146 Gene3D G3DSA:3.40.630.30 1 81 9.2E-16 T 28-03-2018 WM46_RS09565 856bd2bfd6d99cceff92dc9a310d62a2 146 Pfam PF00583 Acetyltransferase (GNAT) family 46 127 8.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS02055 6caa5d79d92c79305b9200f94099382d 220 Pfam PF01144 Coenzyme A transferase 7 214 1.2E-68 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS02055 6caa5d79d92c79305b9200f94099382d 220 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 7 215 4.9E-63 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 WM46_RS02055 6caa5d79d92c79305b9200f94099382d 220 SUPERFAMILY SSF100950 2 217 6.47E-74 T 28-03-2018 WM46_RS02055 6caa5d79d92c79305b9200f94099382d 220 Gene3D G3DSA:3.40.1080.10 1 220 8.2E-72 T 28-03-2018 WM46_RS02055 6caa5d79d92c79305b9200f94099382d 220 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS02055 6caa5d79d92c79305b9200f94099382d 220 SMART SM00882 5 216 6.8E-69 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 WM46_RS18860 a575c618c314679c49cc2587b16bafa7 170 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 1 169 16.772 T 28-03-2018 IPR007336 Der GTPase activator GO:0005096 WM46_RS18860 a575c618c314679c49cc2587b16bafa7 170 Pfam PF04220 Der GTPase activator (YihI) 13 166 1.6E-54 T 28-03-2018 IPR007336 Der GTPase activator GO:0005096 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 443 1.3E-16 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 Gene3D G3DSA:3.30.420.40 242 493 2.0E-33 T 28-03-2018 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 Gene3D G3DSA:3.30.420.40 1 241 3.9E-59 T 28-03-2018 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 249 1.0E-65 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 SUPERFAMILY SSF53067 4 252 5.18E-59 T 28-03-2018 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 SUPERFAMILY SSF53067 252 489 1.67E-38 T 28-03-2018 WM46_RS21045 8cbfd3fb3f4527608f4a1422a9a57a00 494 PIRSF PIRSF000538 2 494 1.9E-84 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 SMART SM00342 185 268 8.5E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 SUPERFAMILY SSF46689 169 218 3.7E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 SUPERFAMILY SSF46689 222 273 3.94E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 237 252 1.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 252 268 1.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 222 264 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 Gene3D G3DSA:1.10.10.60 224 277 2.0E-16 T 28-03-2018 WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 Gene3D G3DSA:2.60.120.10 42 223 3.6E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS20975 0e537f5426bd60bf48056dcb84641aff 283 Pfam PF12833 Helix-turn-helix domain 191 270 9.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS06450 5ec175ab476e2700d7d1692ea0df66aa 143 Gene3D G3DSA:3.40.930.10 4 142 4.4E-24 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS06450 5ec175ab476e2700d7d1692ea0df66aa 143 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 3 139 1.4E-25 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS06450 5ec175ab476e2700d7d1692ea0df66aa 143 SUPERFAMILY SSF55804 4 142 3.14E-29 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS08865 aa25e7a4a0c27ca4050e359ab8dde30e 373 Hamap MF_00515 N-methyl-L-tryptophan oxidase [solA]. 1 372 75.725 T 28-03-2018 IPR023493 N-methyl-L-tryptophan oxidase MTOX GO:0050131|GO:0050660|GO:0055114 WM46_RS08865 aa25e7a4a0c27ca4050e359ab8dde30e 373 SUPERFAMILY SSF51905 2 217 2.12E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08865 aa25e7a4a0c27ca4050e359ab8dde30e 373 SUPERFAMILY SSF51905 314 371 2.12E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08865 aa25e7a4a0c27ca4050e359ab8dde30e 373 SUPERFAMILY SSF54373 213 314 2.35E-17 T 28-03-2018 WM46_RS08865 aa25e7a4a0c27ca4050e359ab8dde30e 373 Gene3D G3DSA:3.50.50.60 1 373 1.6E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08865 aa25e7a4a0c27ca4050e359ab8dde30e 373 Pfam PF01266 FAD dependent oxidoreductase 4 352 8.5E-47 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS01520 8002e552899813b882312976f1366794 182 Pfam PF04315 Elongation factor P hydroxylase 13 175 2.0E-80 T 28-03-2018 IPR007411 Elongation factor P hydroxylase WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 445 9.7E-87 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 Gene3D G3DSA:1.10.285.10 6 61 1.5E-8 T 28-03-2018 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 Gene3D G3DSA:1.10.285.10 374 447 1.5E-24 T 28-03-2018 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 SMART SM00839 204 445 1.0E-95 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 SUPERFAMILY SSF51735 202 446 9.4E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 183 3.3E-49 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 Gene3D G3DSA:3.40.50.720 209 373 6.8E-46 T 28-03-2018 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 PIRSF PIRSF000185 22 447 1.0E-115 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 3.3E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 3.3E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 3.3E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 3.3E-33 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 Gene3D G3DSA:3.40.50.10860 62 190 3.1E-54 T 28-03-2018 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 SUPERFAMILY SSF53223 7 196 1.18E-73 T 28-03-2018 WM46_RS08250 2e5dacddca3a2c58e1a8dd69e4f8df64 447 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 WM46_RS19765 6e6f6ba42b939995a8e8fe53b49dfe97 445 PIRSF PIRSF002746 2 445 1.9E-145 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS19765 6e6f6ba42b939995a8e8fe53b49dfe97 445 Pfam PF02447 GntP family permease 7 444 4.6E-163 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS19765 6e6f6ba42b939995a8e8fe53b49dfe97 445 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 445 1.8E-171 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS19305 f9de714674d1b64ac6831b260f357baa 93 Gene3D G3DSA:3.10.50.40 1 93 7.1E-30 T 28-03-2018 WM46_RS19305 f9de714674d1b64ac6831b260f357baa 93 SUPERFAMILY SSF54534 5 90 2.03E-28 T 28-03-2018 WM46_RS19305 f9de714674d1b64ac6831b260f357baa 93 Pfam PF13616 PPIC-type PPIASE domain 15 90 1.5E-20 T 28-03-2018 WM46_RS19305 f9de714674d1b64ac6831b260f357baa 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 31 51 - T 28-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 WM46_RS24735 ff0e5be2302784e94a600646eb6f4895 233 SUPERFAMILY SSF46894 143 195 5.44E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS24735 ff0e5be2302784e94a600646eb6f4895 233 ProDom PD116027 TRANSCRIPTION DNA-BINDING REGULATION RMBA YQEH ORF3-QACEDELTA1 FUSION CYTOPLASMIC ECS3703 TRANSMEMBRANE 12 201 2.0E-95 T 28-03-2018 WM46_RS11590 8d23baee6ea3853ffc0c72068bc6002d 391 SUPERFAMILY SSF56322 13 389 1.7E-88 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS11590 8d23baee6ea3853ffc0c72068bc6002d 391 Pfam PF00425 chorismate binding enzyme 126 380 7.1E-68 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal WM46_RS11590 8d23baee6ea3853ffc0c72068bc6002d 391 Gene3D G3DSA:3.60.120.10 1 391 2.5E-102 T 28-03-2018 IPR005801 ADC synthase GO:0009058 WM46_RS11590 8d23baee6ea3853ffc0c72068bc6002d 391 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 111 387 2.2E-83 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 Hamap MF_01068 Glucans biosynthesis protein D [mdoD]. 1 544 60.375 T 28-03-2018 IPR023724 Glucan biosynthesis, MdoD WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 PIRSF PIRSF006281 1 538 5.2E-204 T 28-03-2018 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 SUPERFAMILY SSF81296 422 537 9.8E-28 T 28-03-2018 IPR014756 Immunoglobulin E-set WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 45 534 4.0E-181 T 28-03-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 SUPERFAMILY SSF74650 45 422 1.04E-146 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 Gene3D G3DSA:2.70.98.10 45 419 1.6E-155 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS06425 65ff0d14a5aef6b24b136ba27d0a8add 551 Gene3D G3DSA:2.60.40.10 423 538 9.4E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS12920 f053639c3691316f85473fe01c459339 400 Gene3D G3DSA:3.60.21.10 1 63 1.8E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS12920 f053639c3691316f85473fe01c459339 400 Gene3D G3DSA:3.60.21.10 64 277 4.2E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS12920 f053639c3691316f85473fe01c459339 400 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 373 1.5E-23 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain WM46_RS12920 f053639c3691316f85473fe01c459339 400 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 254 1.5E-89 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 WM46_RS12920 f053639c3691316f85473fe01c459339 400 SUPERFAMILY SSF56300 1 335 8.44E-60 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS12920 f053639c3691316f85473fe01c459339 400 Pfam PF00149 Calcineurin-like phosphoesterase 1 224 5.3E-15 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS17090 97c44c206922fb3b1ebb40f0ca859d34 87 SUPERFAMILY SSF159871 3 87 4.71E-27 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS17090 97c44c206922fb3b1ebb40f0ca859d34 87 Gene3D G3DSA:3.30.1660.10 22 87 1.9E-24 T 28-03-2018 IPR025543 Dodecin-like WM46_RS17090 97c44c206922fb3b1ebb40f0ca859d34 87 Pfam PF07338 Protein of unknown function (DUF1471) 35 87 4.5E-21 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS09020 4411a531ed0375e67d605ee865999e6d 167 PIRSF PIRSF028301 1 167 3.3E-58 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 WM46_RS09020 4411a531ed0375e67d605ee865999e6d 167 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 8 161 2.4E-51 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 WM46_RS09020 4411a531ed0375e67d605ee865999e6d 167 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 7 163 4.5E-52 T 28-03-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 WM46_RS00690 76762d57f9cedf33369b6e2fa3cd43b7 388 PIRSF PIRSF006004 14 382 1.2E-148 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS00690 76762d57f9cedf33369b6e2fa3cd43b7 388 SUPERFAMILY SSF102114 120 329 5.49E-15 T 28-03-2018 WM46_RS00690 76762d57f9cedf33369b6e2fa3cd43b7 388 Gene3D G3DSA:3.20.20.70 30 384 1.8E-42 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS00690 76762d57f9cedf33369b6e2fa3cd43b7 388 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 17 373 1.7E-177 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS00690 76762d57f9cedf33369b6e2fa3cd43b7 388 Pfam PF04055 Radical SAM superfamily 124 293 3.6E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS00690 76762d57f9cedf33369b6e2fa3cd43b7 388 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 21 368 75.324 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 WM46_RS11570 c430cfe67746d45c0316e8d26f96d9d8 137 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 134 3.9E-46 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 WM46_RS11570 c430cfe67746d45c0316e8d26f96d9d8 137 Hamap MF_00907 Proofreading thioesterase EntH [entH]. 1 137 54.798 T 28-03-2018 IPR026576 Proofreading thioesterase EntH GO:0009239|GO:0016790 WM46_RS11570 c430cfe67746d45c0316e8d26f96d9d8 137 Gene3D G3DSA:3.10.129.10 1 136 1.3E-27 T 28-03-2018 WM46_RS11570 c430cfe67746d45c0316e8d26f96d9d8 137 Pfam PF03061 Thioesterase superfamily 50 127 1.9E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 WM46_RS11570 c430cfe67746d45c0316e8d26f96d9d8 137 SUPERFAMILY SSF54637 1 136 5.6E-31 T 28-03-2018 IPR029069 HotDog domain WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 SMART SM01005 234 358 3.6E-59 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 Hamap MF_01201 Alanine racemase. 1 358 34.744 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 Pfam PF01168 Alanine racemase, N-terminal domain 8 219 5.2E-72 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 Gene3D G3DSA:3.20.20.10 1 216 2.8E-46 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 267 282 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 288 305 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 26 42 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 155 166 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 192 219 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 340 353 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 60 78 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 120 132 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 PRINTS PR00992 Alanine racemase signature 250 265 2.2E-76 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 TIGRFAM TIGR00492 alr: alanine racemase 3 359 1.5E-147 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 SUPERFAMILY SSF51419 8 235 9.6E-70 T 28-03-2018 IPR029066 PLP-binding barrel WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 Pfam PF00842 Alanine racemase, C-terminal domain 234 357 2.1E-38 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 SUPERFAMILY SSF50621 228 358 1.81E-42 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS21640 be90a47b7d8f4488b958bd6d10d0460b 359 Gene3D G3DSA:2.40.37.10 217 359 2.5E-51 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 331 64.321 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 Gene3D G3DSA:3.30.420.40 145 288 9.3E-19 T 28-03-2018 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 8.6E-137 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 SUPERFAMILY SSF53067 1 309 2.33E-44 T 28-03-2018 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 5.5E-53 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 5.5E-53 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 5.5E-53 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 5.5E-53 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 5.5E-53 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 5.5E-53 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 Gene3D G3DSA:3.30.420.40 1 144 2.7E-42 T 28-03-2018 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 306 6.5E-130 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS16295 0e9a723d042e519d0b63a6ea44b0443f 337 Pfam PF00814 Glycoprotease family 24 307 6.6E-103 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 SUPERFAMILY SSF55604 454 526 5.62E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 Gene3D G3DSA:3.30.1360.60 451 525 1.5E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 Pfam PF02378 Phosphotransferase system, EIIC 19 361 4.5E-87 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 TIGRFAM TIGR02004 PTS-IIBC-malX: PTS system, maltose and glucose-specific IIBC component 8 525 7.1E-256 T 28-03-2018 IPR011301 PTS system, maltose/glucose-specific IIBC component GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.208|MetaCyc: PWY-6619 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 Pfam PF00367 phosphotransferase system, EIIB 455 486 1.4E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 70 372 3.0E-95 T 28-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 420 511 4.7E-27 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS07400 5e4e2ae994305596698333a489f94b88 530 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 464 481 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 154 168 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 Gene3D G3DSA:3.30.2350.10 106 331 4.2E-69 T 28-03-2018 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 SUPERFAMILY SSF55174 33 84 4.71E-9 T 28-03-2018 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 Gene3D G3DSA:3.10.290.10 22 93 2.4E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 SUPERFAMILY SSF55120 109 328 1.76E-66 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 30 328 6.1E-100 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 Pfam PF01479 S4 domain 34 80 1.8E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 SMART SM00363 34 93 9.9E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 WM46_RS08715 3924e1da65e2663f989e9e6777975b57 331 Pfam PF00849 RNA pseudouridylate synthase 115 263 4.1E-30 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 SMART SM00421 151 208 3.1E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.7E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 Gene3D G3DSA:1.10.10.10 131 215 3.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 SMART SM00448 7 120 3.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 Gene3D G3DSA:3.40.50.2300 6 130 1.2E-34 T 28-03-2018 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 SUPERFAMILY SSF52172 7 137 9.11E-34 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 SUPERFAMILY SSF46894 138 210 7.14E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 Pfam PF00072 Response regulator receiver domain 9 121 5.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS02205 3e505b2867e1071d5ff2ac9fee69dd3b 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 3.5E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS26250 58a23d5ca9785e00e75ec2204402e566 263 Pfam PF10263 SprT-like family 14 115 1.0E-11 T 28-03-2018 IPR006640 SprT-like WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 SUPERFAMILY SSF50129 1 186 2.13E-72 T 28-03-2018 IPR011032 GroES-like WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 SUPERFAMILY SSF51735 160 334 2.67E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 Gene3D G3DSA:3.40.50.720 189 312 3.5E-25 T 28-03-2018 WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 Pfam PF00107 Zinc-binding dehydrogenase 197 329 6.2E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 SUPERFAMILY SSF50129 318 369 5.18E-12 T 28-03-2018 IPR011032 GroES-like WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 7.3E-223 T 28-03-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 Gene3D G3DSA:3.90.180.10 1 188 3.3E-60 T 28-03-2018 WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 152 1.2E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS06380 cf441995c1a4dbd913b9b92837e8093a 372 SMART SM00829 12 367 0.003 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS14480 49ebb9351410cec4ef5b3cb98abeb26b 40 Pfam PF15894 Inhibitor of glucose uptake transporter SgrT 3 39 2.6E-12 T 28-03-2018 IPR031767 Inhibitor of glucose uptake transporter SgrT GO:0046325 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 Pfam PF01491 Frataxin-like domain 1 103 7.7E-30 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 Gene3D G3DSA:3.30.920.10 1 106 2.0E-34 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 Hamap MF_00142 Protein CyaY [cyaY]. 1 105 29.034 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 105 2.6E-43 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 SUPERFAMILY SSF55387 1 105 6.63E-40 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 ProSitePatterns PS01344 Frataxin family signature. 50 64 - T 28-03-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS19125 516bfd22ab643b3afd977525664d3652 106 SMART SM01219 1 106 5.4E-56 T 28-03-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 WM46_RS21020 9a51ccb2eaa16cbb2502671334ba3c39 334 Gene3D G3DSA:3.40.50.2300 32 148 4.2E-20 T 28-03-2018 WM46_RS21020 9a51ccb2eaa16cbb2502671334ba3c39 334 SUPERFAMILY SSF53822 33 304 2.03E-64 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS21020 9a51ccb2eaa16cbb2502671334ba3c39 334 Pfam PF13407 Periplasmic binding protein domain 37 292 4.8E-53 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS21020 9a51ccb2eaa16cbb2502671334ba3c39 334 Gene3D G3DSA:3.40.50.2300 149 329 4.8E-12 T 28-03-2018 WM46_RS00560 ba1f68b83488a565baf24ab7f1bc4279 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 309 2.1E-37 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS00560 ba1f68b83488a565baf24ab7f1bc4279 317 Gene3D G3DSA:1.10.3470.10 16 316 2.4E-24 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS16595 bb8aa1fb93948c33fc018032d8ce9d33 157 SUPERFAMILY SSF52728 3 156 1.83E-51 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS16595 bb8aa1fb93948c33fc018032d8ce9d33 157 TIGRFAM TIGR00854 pts-sorbose: PTS system, mannose/fructose/sorbose family, IIB component 3 152 6.4E-71 T 28-03-2018 IPR018455 Phosphotransferase system, sorbose subfamily IIB component, subgroup GO:0005737|GO:0008982|GO:0009401 WM46_RS16595 bb8aa1fb93948c33fc018032d8ce9d33 157 Gene3D G3DSA:3.40.35.10 3 157 3.9E-56 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS16595 bb8aa1fb93948c33fc018032d8ce9d33 157 Pfam PF03830 PTS system sorbose subfamily IIB component 4 149 3.1E-50 T 28-03-2018 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 WM46_RS20695 f86561ef54296f696ec8f982f97b49d4 497 Gene3D G3DSA:3.30.830.10 16 250 5.7E-26 T 28-03-2018 WM46_RS20695 f86561ef54296f696ec8f982f97b49d4 497 SUPERFAMILY SSF63411 322 460 9.25E-7 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS20695 f86561ef54296f696ec8f982f97b49d4 497 SUPERFAMILY SSF63411 29 239 2.62E-23 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 WM46_RS20695 f86561ef54296f696ec8f982f97b49d4 497 Pfam PF00675 Insulinase (Peptidase family M16) 50 158 8.2E-7 T 28-03-2018 IPR011765 Peptidase M16, N-terminal WM46_RS20695 f86561ef54296f696ec8f982f97b49d4 497 Gene3D G3DSA:3.30.830.10 256 471 8.5E-25 T 28-03-2018 WM46_RS20695 f86561ef54296f696ec8f982f97b49d4 497 Pfam PF05193 Peptidase M16 inactive domain 200 377 5.1E-17 T 28-03-2018 IPR007863 Peptidase M16, C-terminal WM46_RS11105 e33053b0dcf76fa431b268d75b7cd2a1 192 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 189 31.969 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 WM46_RS11105 e33053b0dcf76fa431b268d75b7cd2a1 192 PIRSF PIRSF001296 1 192 2.7E-72 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 WM46_RS11105 e33053b0dcf76fa431b268d75b7cd2a1 192 Pfam PF02669 K+-transporting ATPase, c chain 9 187 6.5E-65 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 WM46_RS11105 e33053b0dcf76fa431b268d75b7cd2a1 192 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 188 1.5E-85 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 WM46_RS09520 d45239b4c935cf9f384c07c0115e73ff 262 Pfam PF01614 Bacterial transcriptional regulator 124 247 1.1E-39 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal WM46_RS09520 d45239b4c935cf9f384c07c0115e73ff 262 SUPERFAMILY SSF55781 69 252 4.77E-42 T 28-03-2018 IPR029016 GAF domain-like WM46_RS09520 d45239b4c935cf9f384c07c0115e73ff 262 Gene3D G3DSA:3.30.450.40 76 255 9.5E-39 T 28-03-2018 IPR029016 GAF domain-like WM46_RS09520 d45239b4c935cf9f384c07c0115e73ff 262 Gene3D G3DSA:1.10.10.10 11 69 0.0015 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09520 d45239b4c935cf9f384c07c0115e73ff 262 SMART SM00346 6 94 7.4E-30 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 WM46_RS09520 d45239b4c935cf9f384c07c0115e73ff 262 SUPERFAMILY SSF46785 7 77 2.16E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 SUPERFAMILY SSF55874 5 215 3.01E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 625 0.0 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Gene3D G3DSA:3.30.565.10 17 216 4.9E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 556 620 2.8E-24 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 537 559 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 338 361 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 294 310 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 503 519 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 448 469 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 362 387 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 469 481 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR01098 Topoisomerase IV subunit B signature 311 326 4.4E-158 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 171 3.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 SMART SM00387 27 173 2.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 SUPERFAMILY SSF56719 388 621 6.02E-78 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Gene3D G3DSA:3.30.230.10 217 391 2.3E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 ProSitePatterns PS00177 DNA topoisomerase II signature. 416 424 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 31 46 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 517 529 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 66 79 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 560 576 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 414 428 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 109 123 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 266 279 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 479 495 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 PRINTS PR00418 DNA topoisomerase II family signature 497 514 5.5E-59 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Gene3D G3DSA:3.40.50.670 396 627 2.8E-78 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Pfam PF01751 Toprim domain 413 521 2.1E-12 T 28-03-2018 IPR006171 TOPRIM domain WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Pfam PF00204 DNA gyrase B 218 384 3.7E-39 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 SMART SM00433 34 624 4.3E-211 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 SUPERFAMILY SSF54211 217 382 4.55E-47 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS16105 170f8df95e1098a421c238357b9c1884 630 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 628 47.258 T 28-03-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 WM46_RS22205 66a7731e778868df7d1e5ef04ef68d21 182 Hamap MF_00984 Single-stranded DNA-binding protein. 6 117 37.079 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM46_RS22205 66a7731e778868df7d1e5ef04ef68d21 182 PIRSF PIRSF002070 2 157 1.5E-38 T 28-03-2018 WM46_RS22205 66a7731e778868df7d1e5ef04ef68d21 182 Pfam PF00436 Single-strand binding protein family 6 112 5.4E-38 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 WM46_RS22205 66a7731e778868df7d1e5ef04ef68d21 182 SUPERFAMILY SSF50249 4 166 2.91E-59 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS22205 66a7731e778868df7d1e5ef04ef68d21 182 Gene3D G3DSA:2.40.50.140 1 120 3.1E-43 T 28-03-2018 WM46_RS22205 66a7731e778868df7d1e5ef04ef68d21 182 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 3 166 4.3E-56 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 WM46_RS23935 7531eee9be6b6b625ffde12e73cae75e 323 SUPERFAMILY SSF53850 131 212 6.22E-5 T 28-03-2018 WM46_RS23935 7531eee9be6b6b625ffde12e73cae75e 323 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 306 1.6E-65 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 WM46_RS23935 7531eee9be6b6b625ffde12e73cae75e 323 Gene3D G3DSA:3.40.190.10 142 232 2.1E-4 T 28-03-2018 WM46_RS11025 b3ec6fd6677a00b5a38842ba8212606c 348 PIRSF PIRSF038991 1 348 1.6E-91 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 WM46_RS11025 b3ec6fd6677a00b5a38842ba8212606c 348 Pfam PF05145 Transition state regulatory protein AbrB 29 339 3.6E-95 T 28-03-2018 IPR007820 AbrB family GO:0010468|GO:0016021 WM46_RS11025 b3ec6fd6677a00b5a38842ba8212606c 348 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 6 161 2.8E-39 T 28-03-2018 IPR017516 AbrB duplication WM46_RS11025 b3ec6fd6677a00b5a38842ba8212606c 348 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 184 339 1.9E-44 T 28-03-2018 IPR017516 AbrB duplication WM46_RS20055 b5f84e05ee8f3873c3cdb3f0c8e2be8a 577 Pfam PF05170 AsmA family 1 540 9.3E-27 T 28-03-2018 IPR007844 AsmA WM46_RS25970 3f1d280a5b5a170f1f0d0d5fee9964ce 244 SUPERFAMILY SSF53955 94 175 2.52E-13 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS25970 3f1d280a5b5a170f1f0d0d5fee9964ce 244 SUPERFAMILY SSF53955 17 65 2.52E-13 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS25970 3f1d280a5b5a170f1f0d0d5fee9964ce 244 Gene3D G3DSA:1.10.530.10 15 218 1.3E-15 T 28-03-2018 WM46_RS25970 3f1d280a5b5a170f1f0d0d5fee9964ce 244 Pfam PF01464 Transglycosylase SLT domain 35 170 3.5E-12 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 WM46_RS01075 b294beedb15bcf6f24768c177029f497 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 274 5.7E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01075 b294beedb15bcf6f24768c177029f497 277 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 9 271 3.9E-113 T 28-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 WM46_RS01075 b294beedb15bcf6f24768c177029f497 277 SUPERFAMILY SSF161098 16 264 3.08E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01075 b294beedb15bcf6f24768c177029f497 277 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 5 269 3.8E-114 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 WM46_RS01075 b294beedb15bcf6f24768c177029f497 277 Gene3D G3DSA:1.10.3720.10 12 275 2.0E-46 T 28-03-2018 WM46_RS06495 eb9be6cdb1949c16ed66bac24f7edffe 222 Pfam PF11769 Protein of unknown function (DUF3313) 17 213 1.2E-56 T 28-03-2018 IPR021747 Protein of unknown function DUF3313 WM46_RS07275 786c7c5c970a51ab6a8f9e6bb48c1c94 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 91 107 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS07275 786c7c5c970a51ab6a8f9e6bb48c1c94 417 Gene3D G3DSA:1.20.1250.20 32 224 2.7E-33 T 28-03-2018 WM46_RS07275 786c7c5c970a51ab6a8f9e6bb48c1c94 417 Pfam PF07690 Major Facilitator Superfamily 41 260 7.1E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07275 786c7c5c970a51ab6a8f9e6bb48c1c94 417 SUPERFAMILY SSF103473 25 413 1.83E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07275 786c7c5c970a51ab6a8f9e6bb48c1c94 417 Gene3D G3DSA:1.20.1250.20 232 415 1.8E-14 T 28-03-2018 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 230 28.13 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 Pfam PF02107 Flagellar L-ring protein 47 231 7.0E-60 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 PRINTS PR01008 Flagellar L-ring protein signature 73 85 4.3E-36 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 PRINTS PR01008 Flagellar L-ring protein signature 172 188 4.3E-36 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 PRINTS PR01008 Flagellar L-ring protein signature 146 161 4.3E-36 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 PRINTS PR01008 Flagellar L-ring protein signature 193 207 4.3E-36 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS08760 43fd5c9256d89a81f6cf377393f96095 232 PRINTS PR01008 Flagellar L-ring protein signature 209 223 4.3E-36 T 28-03-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 WM46_RS10700 85a65f0a83782356efa75b95174e9f50 338 Gene3D G3DSA:3.40.50.720 1 207 4.7E-45 T 28-03-2018 WM46_RS10700 85a65f0a83782356efa75b95174e9f50 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 325 3.3E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS10700 85a65f0a83782356efa75b95174e9f50 338 Gene3D G3DSA:3.90.25.10 208 252 2.3E-12 T 28-03-2018 WM46_RS10700 85a65f0a83782356efa75b95174e9f50 338 Gene3D G3DSA:3.90.25.10 253 337 1.9E-20 T 28-03-2018 WM46_RS10700 85a65f0a83782356efa75b95174e9f50 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 335 6.3E-150 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 WM46_RS10700 85a65f0a83782356efa75b95174e9f50 338 SUPERFAMILY SSF51735 1 337 1.28E-101 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS25690 85b8b7a7d34a42cba0b15d30858de7b8 175 Pfam PF11127 Protein of unknown function (DUF2892) 115 172 2.9E-12 T 28-03-2018 IPR021309 Protein of unknown function DUF2892 WM46_RS25690 85b8b7a7d34a42cba0b15d30858de7b8 175 SUPERFAMILY SSF52821 2 154 9.3E-28 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS25690 85b8b7a7d34a42cba0b15d30858de7b8 175 Gene3D G3DSA:3.40.250.10 2 121 7.5E-23 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS25690 85b8b7a7d34a42cba0b15d30858de7b8 175 Pfam PF00581 Rhodanese-like domain 7 99 4.8E-13 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS25690 85b8b7a7d34a42cba0b15d30858de7b8 175 SMART SM00450 6 102 3.0E-15 T 28-03-2018 IPR001763 Rhodanese-like domain WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 Gene3D G3DSA:3.40.50.720 1 281 1.3E-110 T 28-03-2018 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 26 188 2.3E-50 T 28-03-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 SUPERFAMILY SSF48179 283 484 4.76E-64 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 1.2E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 PRINTS PR00084 Mannitol dehydrogenase signature 27 37 1.2E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 PRINTS PR00084 Mannitol dehydrogenase signature 218 231 1.2E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 PRINTS PR00084 Mannitol dehydrogenase signature 179 192 1.2E-21 T 28-03-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 Gene3D G3DSA:1.10.1040.10 282 488 1.3E-64 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 216 460 1.9E-96 T 28-03-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 SUPERFAMILY SSF51735 5 281 2.36E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02325 07cead0e249423121a5e0f2157fbcc67 488 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 218 230 - T 28-03-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 SUPERFAMILY SSF50331 250 364 1.53E-7 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 SUPERFAMILY SSF52540 18 258 3.22E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 Gene3D G3DSA:3.40.50.300 14 272 4.7E-74 T 28-03-2018 WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 Pfam PF08402 TOBE domain 292 372 1.2E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 SMART SM00382 42 225 9.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 Pfam PF00005 ABC transporter 35 174 2.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS08515 23f2cfe80fab1536e89b865136f11d48 378 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 372 1.1E-167 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 WM46_RS20325 6b8baf21323e54a3d4d57616eb78e576 196 Pfam PF05068 Mannitol repressor 30 188 1.7E-59 T 28-03-2018 IPR007761 Mannitol repressor MtlR-like WM46_RS20325 6b8baf21323e54a3d4d57616eb78e576 196 SUPERFAMILY SSF158668 27 188 8.89E-57 T 28-03-2018 WM46_RS20325 6b8baf21323e54a3d4d57616eb78e576 196 Gene3D G3DSA:1.20.120.330 28 188 1.6E-55 T 28-03-2018 WM46_RS21840 6b0e2ffe5eac7dfd224506dba33dfd51 184 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 2 175 1.6E-69 T 28-03-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS21840 6b0e2ffe5eac7dfd224506dba33dfd51 184 Gene3D G3DSA:3.40.50.300 3 182 5.2E-24 T 28-03-2018 WM46_RS21840 6b0e2ffe5eac7dfd224506dba33dfd51 184 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 1 175 33.898 T 28-03-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS21840 6b0e2ffe5eac7dfd224506dba33dfd51 184 SUPERFAMILY SSF52540 1 175 3.07E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21840 6b0e2ffe5eac7dfd224506dba33dfd51 184 SMART SM00072 1 178 2.3E-26 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit WM46_RS21840 6b0e2ffe5eac7dfd224506dba33dfd51 184 Pfam PF13238 AAA domain 5 135 2.7E-8 T 28-03-2018 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 SUPERFAMILY SSF51338 345 377 6.1E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 SUPERFAMILY SSF51338 1 50 6.1E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 PIRSF PIRSF038971 1 378 1.1E-153 T 28-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 Gene3D G3DSA:3.20.20.140 55 298 6.7E-12 T 28-03-2018 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 Gene3D G3DSA:2.30.40.10 1 54 7.9E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 Gene3D G3DSA:2.30.40.10 299 378 6.5E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 SUPERFAMILY SSF51556 50 345 4.28E-23 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 Pfam PF07969 Amidohydrolase family 284 378 2.1E-12 T 28-03-2018 IPR013108 Amidohydrolase 3 WM46_RS21845 ed0ecad7e5adb1cbaa6693ac5f2e2628 378 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 2 378 3.7E-163 T 28-03-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS23380 e136be17ab46e06a0ebc41c6bce1c0fc 141 Pfam PF06877 Regulator of ribonuclease activity B 12 113 5.1E-34 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain WM46_RS23380 e136be17ab46e06a0ebc41c6bce1c0fc 141 SUPERFAMILY SSF89946 2 122 9.68E-42 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain WM46_RS23380 e136be17ab46e06a0ebc41c6bce1c0fc 141 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 4 117 31.363 T 28-03-2018 IPR016716 Regulator of ribonuclease activity B WM46_RS23380 e136be17ab46e06a0ebc41c6bce1c0fc 141 Gene3D G3DSA:3.30.70.970 3 116 6.0E-43 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain WM46_RS23380 e136be17ab46e06a0ebc41c6bce1c0fc 141 PIRSF PIRSF018193 1 141 3.9E-66 T 28-03-2018 IPR016716 Regulator of ribonuclease activity B WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 SUPERFAMILY SSF48498 81 196 4.82E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 SUPERFAMILY SSF46689 5 82 3.17E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 Gene3D G3DSA:1.10.10.60 3 61 1.1E-13 T 28-03-2018 WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.4E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10360 ee5a539e1d2015d1eb3649dd2de6a436 204 Gene3D G3DSA:1.10.357.10 62 204 7.4E-19 T 28-03-2018 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 TIGRFAM TIGR01503 MthylAspMut_E: methylaspartate mutase, E subunit 3 481 8.8E-252 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 Hamap MF_01923 Glutamate mutase epsilon subunit [glmE]. 2 481 54.756 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 Pfam PF06368 Methylaspartate mutase E chain (MutE) 43 481 5.8E-216 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 PIRSF PIRSF001495 1 481 5.1E-244 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 Gene3D G3DSA:3.20.20.240 1 416 1.1E-111 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 SUPERFAMILY SSF51703 1 481 9.42E-199 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10875 3370964499f12d3d1954f2ebcb0b6ee9 481 Gene3D G3DSA:3.90.970.10 417 481 2.2E-27 T 28-03-2018 IPR014714 Glutamate mutase E subunit, C-terminal domain GO:0016866|GO:0019670|GO:0031419 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 WM46_RS04030 5e9f4e183c3aafb8a8e5be9b8d567a11 165 Pfam PF00210 Ferritin-like domain 7 142 3.9E-35 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 WM46_RS04030 5e9f4e183c3aafb8a8e5be9b8d567a11 165 SUPERFAMILY SSF47240 4 161 1.63E-55 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS04030 5e9f4e183c3aafb8a8e5be9b8d567a11 165 Gene3D G3DSA:1.20.1260.10 1 161 2.8E-41 T 28-03-2018 IPR012347 Ferritin-related WM46_RS09390 693182f4ac67d02d9d62c1fc33c38b4f 316 Gene3D G3DSA:3.20.20.100 1 299 4.9E-67 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS09390 693182f4ac67d02d9d62c1fc33c38b4f 316 SUPERFAMILY SSF51430 1 298 3.67E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS09390 693182f4ac67d02d9d62c1fc33c38b4f 316 Pfam PF00248 Aldo/keto reductase family 16 296 6.5E-52 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS16465 d68e9d50e21513a08970e6e84306aae8 233 Gene3D G3DSA:2.60.120.10 12 133 2.4E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS16465 d68e9d50e21513a08970e6e84306aae8 233 Pfam PF02678 Pirin 5 119 4.3E-23 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 WM46_RS16465 d68e9d50e21513a08970e6e84306aae8 233 PIRSF PIRSF006232 1 230 1.1E-32 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 WM46_RS16465 d68e9d50e21513a08970e6e84306aae8 233 SUPERFAMILY SSF51182 1 231 3.46E-44 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS16465 d68e9d50e21513a08970e6e84306aae8 233 Gene3D G3DSA:2.60.120.10 134 233 5.3E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Gene3D G3DSA:3.40.50.300 2 153 2.2E-31 T 28-03-2018 WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Pfam PF12002 MgsA AAA+ ATPase C terminal 268 434 2.1E-66 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Gene3D G3DSA:1.10.3710.10 348 447 8.6E-35 T 28-03-2018 WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 SMART SM00382 49 165 2.8E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 159 4.9E-17 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 SUPERFAMILY SSF48019 252 434 9.07E-73 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Gene3D G3DSA:1.10.8.60 154 242 2.0E-19 T 28-03-2018 WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Pfam PF16193 AAA C-terminal domain 188 267 3.6E-22 T 28-03-2018 IPR032423 AAA C-terminal domain WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 Gene3D G3DSA:1.20.272.10 252 346 3.7E-37 T 28-03-2018 WM46_RS09930 1a9539b9cec43b29ad8535310d7dda83 447 SUPERFAMILY SSF52540 6 234 1.3E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS02830 0790d92f10ae2de79010fa856e3a0b8f 248 TIGRFAM TIGR04009 wcaE: colanic acid biosynthesis glycosyltransferase WcaE 1 248 7.1E-148 T 28-03-2018 IPR024010 Colanic acid biosynthesis, glycosyl transferase, WcaE WM46_RS02830 0790d92f10ae2de79010fa856e3a0b8f 248 Gene3D G3DSA:3.90.550.10 1 207 6.0E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02830 0790d92f10ae2de79010fa856e3a0b8f 248 SUPERFAMILY SSF53448 2 205 2.57E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02830 0790d92f10ae2de79010fa856e3a0b8f 248 Pfam PF00535 Glycosyl transferase family 2 4 114 2.4E-15 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS07555 5b4f6e30ee520a331680091bf8eae26f 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 134 6.3E-69 T 28-03-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 WM46_RS07555 5b4f6e30ee520a331680091bf8eae26f 135 Gene3D G3DSA:3.10.180.10 1 135 1.9E-36 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS07555 5b4f6e30ee520a331680091bf8eae26f 135 SUPERFAMILY SSF54593 1 128 1.75E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS07555 5b4f6e30ee520a331680091bf8eae26f 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 WM46_RS07555 5b4f6e30ee520a331680091bf8eae26f 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 1.5E-25 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM46_RS07555 5b4f6e30ee520a331680091bf8eae26f 135 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 WM46_RS07585 e43e72e00ba3b0b4acc5c7332a76082f 215 SUPERFAMILY SSF53098 13 207 4.5E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS07585 e43e72e00ba3b0b4acc5c7332a76082f 215 Hamap MF_00157 Ribonuclease T [rnt]. 1 215 118.91 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 WM46_RS07585 e43e72e00ba3b0b4acc5c7332a76082f 215 SMART SM00479 18 203 8.3E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS07585 e43e72e00ba3b0b4acc5c7332a76082f 215 Gene3D G3DSA:3.30.420.10 9 210 6.6E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS07585 e43e72e00ba3b0b4acc5c7332a76082f 215 TIGRFAM TIGR01298 RNaseT: ribonuclease T 10 208 7.2E-111 T 28-03-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 WM46_RS07585 e43e72e00ba3b0b4acc5c7332a76082f 215 Pfam PF00929 Exonuclease 20 194 4.9E-39 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS15655 74834a966a597359473bca2e78247a3e 80 Pfam PF13711 Domain of unknown function (DUF4160) 9 76 1.1E-21 T 28-03-2018 IPR025427 Protein of unknown function DUF4160 WM46_RS20165 84d80b0312437de3fe5a4418de7c5fab 425 Pfam PF00534 Glycosyl transferases group 1 234 398 5.8E-13 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS20165 84d80b0312437de3fe5a4418de7c5fab 425 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 211 8.4E-67 T 28-03-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 WM46_RS20165 84d80b0312437de3fe5a4418de7c5fab 425 Gene3D G3DSA:3.40.50.2000 210 402 6.0E-15 T 28-03-2018 WM46_RS20165 84d80b0312437de3fe5a4418de7c5fab 425 SUPERFAMILY SSF53756 57 420 9.42E-21 T 28-03-2018 WM46_RS20165 84d80b0312437de3fe5a4418de7c5fab 425 Gene3D G3DSA:3.40.50.2000 50 204 2.0E-4 T 28-03-2018 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 3 176 9.5E-70 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 SUPERFAMILY SSF54197 3 177 4.54E-72 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 183 345 6.4E-73 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 PIRSF PIRSF000808 1 341 7.5E-128 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 SUPERFAMILY SSF54197 179 345 9.12E-61 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 151 168 - T 28-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 Gene3D G3DSA:3.30.428.10 165 345 3.8E-60 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 Gene3D G3DSA:3.30.428.10 45 164 6.0E-51 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 WM46_RS10705 72213ffe76e589b2d1f1536d8b7608f3 348 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 1 347 1.6E-209 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 SUPERFAMILY SSF52096 31 181 1.82E-30 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 SUPERFAMILY SSF52096 212 286 1.82E-30 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 Gene3D G3DSA:3.90.226.10 56 318 6.5E-26 T 28-03-2018 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 334 541 5.0E-53 T 28-03-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 Gene3D G3DSA:3.90.226.10 321 612 1.8E-49 T 28-03-2018 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 Pfam PF01343 Peptidase family S49 392 543 2.4E-53 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 Pfam PF01343 Peptidase family S49 141 295 1.5E-45 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 609 1.2E-269 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 SUPERFAMILY SSF52096 468 530 1.22E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 SUPERFAMILY SSF52096 320 440 1.22E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS08300 c87fef3f946ce0d6cc64e258cf0da325 618 PIRSF PIRSF001217 8 618 4.7E-227 T 28-03-2018 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 WM46_RS00520 73fc35b99a2d3dd4d673c609e1cbf07f 397 Gene3D G3DSA:3.30.420.40 203 397 1.8E-33 T 28-03-2018 WM46_RS00520 73fc35b99a2d3dd4d673c609e1cbf07f 397 Gene3D G3DSA:3.30.420.40 68 202 2.0E-15 T 28-03-2018 WM46_RS00520 73fc35b99a2d3dd4d673c609e1cbf07f 397 Pfam PF00480 ROK family 114 352 1.6E-31 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 WM46_RS00520 73fc35b99a2d3dd4d673c609e1cbf07f 397 SUPERFAMILY SSF53067 84 351 3.54E-37 T 28-03-2018 WM46_RS00520 73fc35b99a2d3dd4d673c609e1cbf07f 397 Gene3D G3DSA:1.10.10.10 5 67 6.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS00520 73fc35b99a2d3dd4d673c609e1cbf07f 397 SUPERFAMILY SSF46785 11 64 3.93E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09060 19735054ac4c5a8dacd9fca332068771 468 Gene3D G3DSA:1.25.40.10 39 465 0.003 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS09060 19735054ac4c5a8dacd9fca332068771 468 TIGRFAM TIGR03362 VI_chp_7: type VI secretion-associated protein, VC_A0119 family 9 463 4.2E-141 T 28-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 WM46_RS09060 19735054ac4c5a8dacd9fca332068771 468 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ 220 462 6.8E-75 T 28-03-2018 IPR017739 Type VI secretion system-associated, VCA0119 WM46_RS03220 f1d88782e6d15a15933a2636527c1b22 162 Pfam PF00959 Phage lysozyme 46 151 3.0E-23 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 WM46_RS03220 f1d88782e6d15a15933a2636527c1b22 162 Gene3D G3DSA:1.10.530.40 1 162 2.1E-47 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 WM46_RS03220 f1d88782e6d15a15933a2636527c1b22 162 SUPERFAMILY SSF53955 6 160 1.94E-50 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS01265 892062d914cb813b56cbea1ac0c267e2 400 Pfam PF07670 Nucleoside recognition 92 189 1.5E-7 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 WM46_RS01265 892062d914cb813b56cbea1ac0c267e2 400 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 193 398 7.1E-59 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 WM46_RS01265 892062d914cb813b56cbea1ac0c267e2 400 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 398 2.2E-146 T 28-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 WM46_RS01265 892062d914cb813b56cbea1ac0c267e2 400 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 10 82 1.1E-20 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 WM46_RS06690 6e87df333a9d7437456203b579f97146 75 SUPERFAMILY SSF55331 2 74 3.0E-19 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily WM46_RS06690 6e87df333a9d7437456203b579f97146 75 PIRSF PIRSF037799 1 75 1.1E-30 T 28-03-2018 IPR017284 Tautomerase PptA GO:0005737|GO:0016862 WM46_RS06690 6e87df333a9d7437456203b579f97146 75 Hamap MF_00718 Tautomerase PptA [pptA]. 1 75 28.625 T 28-03-2018 IPR017284 Tautomerase PptA GO:0005737|GO:0016862 WM46_RS06690 6e87df333a9d7437456203b579f97146 75 Pfam PF01361 Tautomerase enzyme 2 53 3.1E-15 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 WM46_RS06690 6e87df333a9d7437456203b579f97146 75 Gene3D G3DSA:3.30.429.10 2 65 3.7E-19 T 28-03-2018 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Pfam PF00994 Probable molybdopterin binding domain 182 317 2.0E-27 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Gene3D G3DSA:3.90.105.10 27 61 1.5E-11 T 28-03-2018 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 SUPERFAMILY SSF63882 7 177 1.44E-58 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 SMART SM00852 181 318 1.6E-43 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 254 287 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 168 5.0E-47 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 SUPERFAMILY SSF63867 328 407 7.46E-25 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 177 314 1.7E-34 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Gene3D G3DSA:2.40.340.10 329 406 5.3E-22 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Gene3D G3DSA:3.40.980.10 151 325 3.6E-53 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Gene3D G3DSA:2.170.190.11 62 142 7.0E-31 T 28-03-2018 WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 SUPERFAMILY SSF53218 178 321 1.31E-43 T 28-03-2018 IPR001453 MoaB/Mog domain WM46_RS10295 126a7ac679026f1c0c60acb7104a9687 411 Pfam PF03454 MoeA C-terminal region (domain IV) 332 404 1.4E-20 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 WM46_RS05930 d5273a1859944499c2b40c1764366bf3 102 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 1 94 22.751 T 28-03-2018 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 WM46_RS05930 d5273a1859944499c2b40c1764366bf3 102 Pfam PF06305 Lipopolysaccharide assembly protein A domain 23 85 1.4E-20 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 WM46_RS10385 f248798e7377994cacc92ce10105872a 528 Pfam PF00884 Sulfatase 218 483 5.9E-38 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS10385 f248798e7377994cacc92ce10105872a 528 SUPERFAMILY SSF53649 220 484 2.18E-17 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS10385 f248798e7377994cacc92ce10105872a 528 Gene3D G3DSA:3.40.720.10 209 488 2.7E-17 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 Gene3D G3DSA:2.40.50.100 1 64 1.0E-19 T 28-03-2018 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 Gene3D G3DSA:2.40.50.100 65 132 2.9E-20 T 28-03-2018 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 73 140 4.1E-19 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 2 69 1.7E-22 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 SUPERFAMILY SSF50331 1 71 7.29E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 Pfam PF03459 TOBE domain 76 136 3.6E-15 T 28-03-2018 IPR005116 Transport-associated OB, type 1 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 Pfam PF03459 TOBE domain 4 66 1.5E-14 T 28-03-2018 IPR005116 Transport-associated OB, type 1 WM46_RS25350 c891f093bff5a5d69e91c42e21f29086 142 SUPERFAMILY SSF50331 73 140 3.64E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 10 199 4.5E-46 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 Gene3D G3DSA:3.40.50.300 4 213 2.9E-56 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 TIGRFAM TIGR00235 udk: uridine kinase 5 213 2.8E-98 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 PRINTS PR00988 Uridine kinase signature 157 168 3.7E-39 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 PRINTS PR00988 Uridine kinase signature 8 25 3.7E-39 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 PRINTS PR00988 Uridine kinase signature 143 153 3.7E-39 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 PRINTS PR00988 Uridine kinase signature 179 192 3.7E-39 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 PRINTS PR00988 Uridine kinase signature 87 102 3.7E-39 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 PRINTS PR00988 Uridine kinase signature 42 53 3.7E-39 T 28-03-2018 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 Hamap MF_00551 Uridine kinase [udk]. 5 213 41.917 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 WM46_RS02765 7361242439ce8c819b352b5f5a1ee3e4 213 SUPERFAMILY SSF52540 8 205 1.06E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 Pfam PF03466 LysR substrate binding domain 90 294 5.9E-39 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 Gene3D G3DSA:3.40.190.10 90 178 3.2E-13 T 28-03-2018 WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.2E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 Gene3D G3DSA:1.10.10.10 3 89 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 SUPERFAMILY SSF53850 91 295 1.41E-41 T 28-03-2018 WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 Gene3D G3DSA:3.40.190.10 179 268 7.7E-25 T 28-03-2018 WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 SUPERFAMILY SSF46785 5 114 5.71E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS13230 7d5db0fa86f32b49808cce09ee0a8119 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS08460 3459f79d85caa08123ad67be62dd667c 262 SUPERFAMILY SSF46894 8 104 1.16E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS08460 3459f79d85caa08123ad67be62dd667c 262 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 103 9.5E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS08460 3459f79d85caa08123ad67be62dd667c 262 SMART SM00862 26 104 3.4E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS08460 3459f79d85caa08123ad67be62dd667c 262 Gene3D G3DSA:1.10.10.10 4 111 5.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS20535 f0f5ef94a401b5830db578aec9a6c7ff 249 Gene3D G3DSA:3.20.20.150 1 248 3.4E-26 T 28-03-2018 WM46_RS20535 f0f5ef94a401b5830db578aec9a6c7ff 249 SUPERFAMILY SSF51658 4 248 1.87E-59 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 188 337 3.5E-20 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 8 167 3.3E-41 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 SUPERFAMILY SSF55120 3 339 4.03E-103 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 5 342 28.799 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 3 341 3.7E-97 T 28-03-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 Gene3D G3DSA:3.30.2340.10 167 302 6.5E-29 T 28-03-2018 WM46_RS25275 c3f85192de3b53ad896bd7ebba9acc19 349 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 77 90 - T 28-03-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 ProSitePatterns PS00761 Signal peptidases I signature 3. 269 282 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 ProSitePatterns PS00760 Signal peptidases I lysine active site. 146 158 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 66 159 5.1E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 260 305 5.5E-17 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 144 156 2.9E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 80 96 2.9E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 264 283 2.9E-25 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 Pfam PF10502 Signal peptidase, peptidase S26 254 302 2.0E-7 T 28-03-2018 IPR019533 Peptidase S26 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 Pfam PF00717 Peptidase S24-like 86 159 1.5E-20 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 SUPERFAMILY SSF51306 78 323 5.58E-84 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 ProSitePatterns PS00501 Signal peptidases I serine active site. 89 96 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 WM46_RS00400 4baf1e08092fb01d631325b556f9b6e0 324 Gene3D G3DSA:2.10.109.10 76 320 1.7E-56 T 28-03-2018 WM46_RS18670 43bcc3a5c67826bf08cbc99b2620b637 70 SUPERFAMILY SSF159871 2 70 7.19E-15 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS18670 43bcc3a5c67826bf08cbc99b2620b637 70 Pfam PF07338 Protein of unknown function (DUF1471) 24 68 3.4E-11 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS18670 43bcc3a5c67826bf08cbc99b2620b637 70 Gene3D G3DSA:3.30.1660.10 10 70 4.6E-16 T 28-03-2018 IPR025543 Dodecin-like WM46_RS13630 56ba8282339734f7629d98ec99ebafe2 62 Gene3D G3DSA:1.10.10.10 10 60 4.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13630 56ba8282339734f7629d98ec99ebafe2 62 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 10 57 4.7E-12 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA WM46_RS22620 f3362071f76f23928b33d4b793029353 330 PIRSF PIRSF037112 4 330 5.1E-114 T 28-03-2018 IPR017113 Antirestriction, ArdC WM46_RS22620 f3362071f76f23928b33d4b793029353 330 Pfam PF08401 Domain of unknown function (DUF1738) 17 145 1.1E-35 T 28-03-2018 IPR013610 Domain of unknown function DUF1738 WM46_RS07845 4850ef247d6399c7abc38fcd71713eab 495 SUPERFAMILY SSF101960 41 86 3.92E-137 T 28-03-2018 WM46_RS07845 4850ef247d6399c7abc38fcd71713eab 495 SUPERFAMILY SSF101960 125 492 3.92E-137 T 28-03-2018 WM46_RS07845 4850ef247d6399c7abc38fcd71713eab 495 Pfam PF01458 Uncharacterized protein family (UPF0051) 234 466 7.0E-69 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 WM46_RS07845 4850ef247d6399c7abc38fcd71713eab 495 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 21 486 3.3E-194 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.3E-64 T 28-03-2018 IPR023798 Ribosomal protein S7 domain WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 Gene3D G3DSA:1.10.455.10 6 156 7.9E-61 T 28-03-2018 IPR023798 Ribosomal protein S7 domain WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.5E-71 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.203 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 PIRSF PIRSF002122 3 156 6.8E-63 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17585 07946724f0f81b26c702851b81e533a0 156 SUPERFAMILY SSF47973 6 149 1.26E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 SMART SM00869 1264 1537 5.5E-44 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 SUPERFAMILY SSF103515 1231 1548 1.57E-48 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 Gene3D G3DSA:2.160.20.20 705 1204 9.5E-48 T 28-03-2018 IPR012332 P22 tailspike C-terminal domain-like WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 Pfam PF03797 Autotransporter beta-domain 1267 1526 3.2E-48 T 28-03-2018 IPR005546 Autotransporter beta-domain WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 449 471 6.8E-6 T 28-03-2018 IPR013425 Autotransporter-associated beta strand repeat WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 330 370 1.5E-7 T 28-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 117 162 4.2E-9 T 28-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 221 267 2.2E-10 T 28-03-2018 IPR030895 T5SS/PEP-CTERM-associated repeat WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 SUPERFAMILY SSF51126 743 1201 2.61E-41 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 Gene3D G3DSA:2.40.128.130 1222 1548 4.2E-49 T 28-03-2018 WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1097 1548 6.1E-121 T 28-03-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 WM46_RS25775 f700990467a197d16b60bb0b214ee395 1548 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 1.3E-6 T 28-03-2018 IPR024973 ESPR domain WM46_RS01000 cec33fb72c9a4ca87560841f10c5d352 408 Pfam PF04346 Ethanolamine utilisation protein, EutH 3 391 9.9E-141 T 28-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 WM46_RS01000 cec33fb72c9a4ca87560841f10c5d352 408 PIRSF PIRSF019466 1 407 2.9E-129 T 28-03-2018 IPR007441 Ethanolamine utilisation protein EutH GO:0016021|GO:0034228|GO:0034229 WM46_RS09605 0685ea0d6efd8fe949e9f63af7c6b276 137 SUPERFAMILY SSF51735 4 135 3.33E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS09605 0685ea0d6efd8fe949e9f63af7c6b276 137 Pfam PF13380 CoA binding domain 14 130 2.4E-38 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS09605 0685ea0d6efd8fe949e9f63af7c6b276 137 SMART SM00881 9 104 1.0E-25 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS09605 0685ea0d6efd8fe949e9f63af7c6b276 137 Gene3D G3DSA:3.40.50.720 10 134 1.2E-32 T 28-03-2018 WM46_RS15120 a8712de0e5ca882c325ea7f48bfc56a8 108 Pfam PF04320 Protein with unknown function (DUF469) 7 107 9.9E-43 T 28-03-2018 IPR007416 Protein of unknown function DUF469 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 SUPERFAMILY SSF53706 43 661 4.84E-160 T 28-03-2018 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 Gene3D G3DSA:3.40.228.10 181 453 4.2E-58 T 28-03-2018 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 Gene3D G3DSA:2.40.40.20 650 809 8.1E-32 T 28-03-2018 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 Pfam PF00384 Molybdopterin oxidoreductase 85 554 3.1E-102 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 497 514 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 713 740 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 Gene3D G3DSA:3.90.55.10 36 122 2.0E-11 T 28-03-2018 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 Gene3D G3DSA:3.90.55.10 516 605 2.4E-21 T 28-03-2018 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 31 5.9E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 Pfam PF01568 Molydopterin dinucleotide binding domain 674 789 4.3E-26 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 SUPERFAMILY SSF50692 667 812 6.78E-40 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS23370 d7842db17661981792c7f89bd87fed77 815 TIGRFAM TIGR00509 bisC_fam: molybdopterin guanine dinucleotide-containing S/N-oxide reductases 42 812 0.0 T 28-03-2018 IPR006658 Molybdopterin guanine dinucleotide-containing S/N-oxide reductase GO:0016491|GO:0055114 WM46_RS08545 1dd6db940d36a6a6554e089f777b11b7 414 Gene3D G3DSA:1.20.1250.20 1 404 0.012 T 28-03-2018 WM46_RS08545 1dd6db940d36a6a6554e089f777b11b7 414 Pfam PF02687 FtsX-like permease family 302 407 1.8E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS08545 1dd6db940d36a6a6554e089f777b11b7 414 TIGRFAM TIGR02213 lolE_release: lipoprotein releasing system, transmembrane protein LolE 5 414 8.4E-233 T 28-03-2018 IPR011926 Lipoprotein-releasing system transmembrane protein LolC/E, gammaproteobacteria type GO:0006810|GO:0009276|GO:0016021 WM46_RS08545 1dd6db940d36a6a6554e089f777b11b7 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 413 2.3E-166 T 28-03-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 WM46_RS08545 1dd6db940d36a6a6554e089f777b11b7 414 Pfam PF12704 MacB-like periplasmic core domain 27 239 2.4E-16 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS09725 fa8912376c361847227f4448e9a0dba4 381 Pfam PF00296 Luciferase-like monooxygenase 5 326 9.6E-88 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 WM46_RS09725 fa8912376c361847227f4448e9a0dba4 381 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 4 379 70.591 T 28-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 WM46_RS09725 fa8912376c361847227f4448e9a0dba4 381 Gene3D G3DSA:3.20.20.30 1 354 2.3E-92 T 28-03-2018 WM46_RS09725 fa8912376c361847227f4448e9a0dba4 381 SUPERFAMILY SSF51679 3 349 4.84E-99 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 WM46_RS09725 fa8912376c361847227f4448e9a0dba4 381 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 4 349 7.6E-191 T 28-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 SUPERFAMILY SSF54368 3 99 3.01E-36 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 4 468 3.5E-220 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 6.9E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 SUPERFAMILY SSF55931 102 468 1.77E-138 T 28-03-2018 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 1.4E-139 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 SMART SM01230 102 379 4.6E-152 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 Gene3D G3DSA:3.10.20.70 2 104 3.7E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 Gene3D G3DSA:3.30.590.10 105 457 7.8E-124 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 WM46_RS18835 63b14171aa4c4bbbf2bf0da20986f95c 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 WM46_RS09295 50ea77396ae3a734c99e6e7535e2af78 499 Pfam PF01384 Phosphate transporter family 30 488 2.0E-84 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 WM46_RS19505 0a6f5dacd0b1bf845d60f5b9e16da4dd 156 Gene3D G3DSA:1.20.5.620 62 122 5.5E-16 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain WM46_RS19505 0a6f5dacd0b1bf845d60f5b9e16da4dd 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 3.8E-61 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 WM46_RS19505 0a6f5dacd0b1bf845d60f5b9e16da4dd 156 SUPERFAMILY SSF81573 63 121 2.22E-15 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain WM46_RS19505 0a6f5dacd0b1bf845d60f5b9e16da4dd 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 13.07 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 WM46_RS19505 0a6f5dacd0b1bf845d60f5b9e16da4dd 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 5.7E-40 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 WM46_RS05750 8f99753b2e8c84b562cdccb6f56e6335 306 Gene3D G3DSA:1.10.3720.10 2 294 1.6E-41 T 28-03-2018 WM46_RS05750 8f99753b2e8c84b562cdccb6f56e6335 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 3.8E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS05750 8f99753b2e8c84b562cdccb6f56e6335 306 SUPERFAMILY SSF161098 88 291 1.53E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS17720 dc34ab5d45e66b4d75bfb85c13647ade 393 Gene3D G3DSA:1.20.1250.20 1 198 2.9E-20 T 28-03-2018 WM46_RS17720 dc34ab5d45e66b4d75bfb85c13647ade 393 Hamap MF_01044 Protein TsgA [tsgA]. 1 388 30.386 T 28-03-2018 IPR023528 Major facilitator superfamily transporter, TsgA WM46_RS17720 dc34ab5d45e66b4d75bfb85c13647ade 393 Pfam PF07690 Major Facilitator Superfamily 14 320 2.7E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS17720 dc34ab5d45e66b4d75bfb85c13647ade 393 Gene3D G3DSA:1.20.1250.20 199 387 4.2E-15 T 28-03-2018 WM46_RS17720 dc34ab5d45e66b4d75bfb85c13647ade 393 SUPERFAMILY SSF103473 4 387 7.98E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 Hamap MF_01269 Shikimate kinase 2 [aroL]. 1 173 41.612 T 28-03-2018 IPR027544 Shikimate kinase 2 GO:0004765|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 Pfam PF01202 Shikimate kinase 11 168 5.1E-47 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 PRINTS PR01100 Shikimate kinase family signature 29 42 1.2E-24 T 28-03-2018 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 PRINTS PR01100 Shikimate kinase family signature 74 83 1.2E-24 T 28-03-2018 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 PRINTS PR01100 Shikimate kinase family signature 5 20 1.2E-24 T 28-03-2018 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 PRINTS PR01100 Shikimate kinase family signature 57 65 1.2E-24 T 28-03-2018 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 PRINTS PR01100 Shikimate kinase family signature 95 112 1.2E-24 T 28-03-2018 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 SUPERFAMILY SSF52540 5 169 5.72E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 Gene3D G3DSA:3.40.50.300 1 173 6.3E-29 T 28-03-2018 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 ProSitePatterns PS01128 Shikimate kinase signature. 58 82 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS12960 ca151ae69f472f8cae4b54355361b636 181 Hamap MF_00109 Shikimate kinase [aroK]. 2 169 24.272 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS16965 99000ea2803b5e413db3108030956112 239 SUPERFAMILY SSF53955 51 228 1.24E-61 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS16965 99000ea2803b5e413db3108030956112 239 Gene3D G3DSA:1.10.3810.10 46 236 1.2E-56 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS16965 99000ea2803b5e413db3108030956112 239 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 5 230 43.282 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 WM46_RS16965 99000ea2803b5e413db3108030956112 239 Pfam PF00912 Transglycosylase 58 224 1.4E-51 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 WM46_RS16965 99000ea2803b5e413db3108030956112 239 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 9 228 2.0E-86 T 28-03-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 WM46_RS07110 392872c3a9102fd06acd4b35618b1b32 357 Gene3D G3DSA:1.10.3470.10 43 354 8.6E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS07110 392872c3a9102fd06acd4b35618b1b32 357 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 42 351 1.7E-126 T 28-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC WM46_RS07110 392872c3a9102fd06acd4b35618b1b32 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 340 5.4E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS12855 f95c2c368307d6af0df404d30eb1cd00 320 Pfam PF00294 pfkB family carbohydrate kinase 22 299 6.5E-33 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS12855 f95c2c368307d6af0df404d30eb1cd00 320 Gene3D G3DSA:3.40.1190.20 1 312 3.9E-44 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS12855 f95c2c368307d6af0df404d30eb1cd00 320 SUPERFAMILY SSF53613 1 304 5.3E-48 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS12855 f95c2c368307d6af0df404d30eb1cd00 320 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 Pfam PF01175 Urocanase Rossmann-like domain 140 348 2.6E-85 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 PIRSF PIRSF001423 1 560 1.6E-293 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 Pfam PF17391 Urocanase N-terminal domain 11 137 9.2E-63 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 Pfam PF17392 Urocanase C-terminal domain 351 544 4.3E-92 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 Gene3D G3DSA:3.40.1770.10 195 554 3.1E-162 T 28-03-2018 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 Gene3D G3DSA:3.40.1770.10 9 151 1.9E-29 T 28-03-2018 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 Hamap MF_00577 Urocanate hydratase [hutU]. 2 555 49.552 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 TIGRFAM TIGR01228 hutU: urocanate hydratase 9 553 2.9E-299 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 SUPERFAMILY SSF111326 6 554 3.92E-259 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS10610 7ae578f681d6b4d0872b3fe14e229702 561 ProSitePatterns PS01233 Urocanase signature. 441 456 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 WM46_RS11675 33169b5c550ea58200c326a6182f9747 276 Gene3D G3DSA:3.40.50.970 5 276 4.3E-61 T 28-03-2018 WM46_RS11675 33169b5c550ea58200c326a6182f9747 276 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 22 268 3.2E-38 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 WM46_RS11675 33169b5c550ea58200c326a6182f9747 276 SUPERFAMILY SSF52518 6 273 1.83E-72 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold WM46_RS14025 b743349f69dc4c002bdaa68e52d477df 266 Pfam PF01497 Periplasmic binding protein 26 218 5.6E-21 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS14025 b743349f69dc4c002bdaa68e52d477df 266 Gene3D G3DSA:3.40.50.1980 141 266 7.7E-23 T 28-03-2018 WM46_RS14025 b743349f69dc4c002bdaa68e52d477df 266 Gene3D G3DSA:3.40.50.1980 22 140 1.3E-26 T 28-03-2018 WM46_RS14025 b743349f69dc4c002bdaa68e52d477df 266 SUPERFAMILY SSF53807 25 262 2.98E-54 T 28-03-2018 WM46_RS14025 b743349f69dc4c002bdaa68e52d477df 266 Hamap MF_01000 Vitamin B12-binding protein [btuF]. 2 266 46.073 T 28-03-2018 IPR023544 ABC transporter, vitamin B12-binding protein GO:0015889|GO:0031419|GO:0042597 WM46_RS15125 e616dbd9de0dc312c7533d54cff124a5 239 SUPERFAMILY SSF53335 18 237 7.64E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS15125 e616dbd9de0dc312c7533d54cff124a5 239 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 24 238 30.649 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 WM46_RS15125 e616dbd9de0dc312c7533d54cff124a5 239 Pfam PF02390 Putative methyltransferase 64 233 3.5E-62 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 WM46_RS15125 e616dbd9de0dc312c7533d54cff124a5 239 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 49 238 1.4E-75 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 WM46_RS15125 e616dbd9de0dc312c7533d54cff124a5 239 Gene3D G3DSA:3.40.50.150 30 239 1.7E-28 T 28-03-2018 WM46_RS09855 21c0fc09d01f67f7e5a227a659ea8559 227 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 219 7.5E-97 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 WM46_RS09855 21c0fc09d01f67f7e5a227a659ea8559 227 SUPERFAMILY SSF52540 6 224 4.69E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09855 21c0fc09d01f67f7e5a227a659ea8559 227 Gene3D G3DSA:3.40.50.300 5 224 9.5E-53 T 28-03-2018 WM46_RS09855 21c0fc09d01f67f7e5a227a659ea8559 227 Hamap MF_00238 Cytidylate kinase [cmk]. 6 224 34.6 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 WM46_RS09855 21c0fc09d01f67f7e5a227a659ea8559 227 Pfam PF02224 Cytidylate kinase 8 221 3.5E-85 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 293 319 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 123 139 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 7.9E-97 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 Gene3D G3DSA:3.40.190.10 24 145 3.6E-18 T 28-03-2018 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 Pfam PF13416 Bacterial extracellular solute-binding protein 42 312 1.1E-39 T 28-03-2018 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 PIRSF PIRSF019574 1 348 2.0E-135 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 Gene3D G3DSA:3.40.190.10 146 300 1.5E-40 T 28-03-2018 WM46_RS08530 14ddcc497ecff4e296a6342899ae3bcc 348 SUPERFAMILY SSF53850 27 345 3.44E-98 T 28-03-2018 WM46_RS20630 3a58b024b7f32f31e7867808ce351460 67 Pfam PF13940 Toxin Ldr, type I toxin-antitoxin system 33 67 5.1E-21 T 28-03-2018 IPR025253 Type I toxin-antitoxin system, toxin Ldr WM46_RS25235 0014a6ea7a249bd5e3ae8efdeed8e059 302 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 4 302 59.558 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM46_RS25235 0014a6ea7a249bd5e3ae8efdeed8e059 302 PIRSF PIRSF002936 1 302 7.3E-156 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM46_RS25235 0014a6ea7a249bd5e3ae8efdeed8e059 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 257 9.5E-67 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 WM46_RS25235 0014a6ea7a249bd5e3ae8efdeed8e059 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 302 6.5E-169 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 WM46_RS25235 0014a6ea7a249bd5e3ae8efdeed8e059 302 SUPERFAMILY SSF52402 6 209 2.43E-75 T 28-03-2018 WM46_RS25235 0014a6ea7a249bd5e3ae8efdeed8e059 302 Gene3D G3DSA:3.40.50.620 2 300 1.1E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS01645 7ba04e94e358b8f148a423743550ee25 169 SUPERFAMILY SSF55729 2 164 2.48E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS01645 7ba04e94e358b8f148a423743550ee25 169 Pfam PF13302 Acetyltransferase (GNAT) domain 8 141 7.1E-28 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS01645 7ba04e94e358b8f148a423743550ee25 169 Gene3D G3DSA:3.40.630.30 1 168 1.0E-33 T 28-03-2018 WM46_RS11380 dfbabe18fbd5ce7ade2e1f5861475928 105 Gene3D G3DSA:3.30.460.10 1 105 6.6E-34 T 28-03-2018 WM46_RS11380 dfbabe18fbd5ce7ade2e1f5861475928 105 SUPERFAMILY SSF81301 4 105 3.27E-36 T 28-03-2018 WM46_RS11380 dfbabe18fbd5ce7ade2e1f5861475928 105 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.212 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS WM46_RS11380 dfbabe18fbd5ce7ade2e1f5861475928 105 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 2.1E-27 T 28-03-2018 WM46_RS11380 dfbabe18fbd5ce7ade2e1f5861475928 105 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 2.6E-37 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS WM46_RS14130 5c0ad8a8eef3903be39dcf9724ac15e2 146 SUPERFAMILY SSF53062 1 125 4.06E-27 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS14130 5c0ad8a8eef3903be39dcf9724ac15e2 146 Pfam PF03610 PTS system fructose IIA component 3 116 5.0E-27 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS14130 5c0ad8a8eef3903be39dcf9724ac15e2 146 Gene3D G3DSA:3.40.50.510 1 136 5.2E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 299 318 6.4E-30 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 150 171 6.4E-30 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 97 123 6.4E-30 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 125 144 6.4E-30 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 200 223 6.4E-30 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 Pfam PF01566 Natural resistance-associated macrophage protein 38 383 3.8E-126 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 1 409 38.283 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS01270 0767427f804f65565e424ef7120d7537 412 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 19 377 2.6E-99 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 WM46_RS13465 307ca82daa537bfc147fa9b0d376813b 176 Pfam PF00959 Phage lysozyme 47 165 1.6E-27 T 28-03-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 WM46_RS13465 307ca82daa537bfc147fa9b0d376813b 176 SUPERFAMILY SSF53955 27 172 7.67E-34 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS13465 307ca82daa537bfc147fa9b0d376813b 176 Gene3D G3DSA:1.10.530.40 1 175 5.9E-43 T 28-03-2018 IPR023347 Lysozyme domain GO:0003796 WM46_RS01370 f2d9b37eac3ac47ce08113c576b03022 397 Gene3D G3DSA:1.20.1250.20 195 386 8.9E-23 T 28-03-2018 WM46_RS01370 f2d9b37eac3ac47ce08113c576b03022 397 Pfam PF07690 Major Facilitator Superfamily 27 342 2.0E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS01370 f2d9b37eac3ac47ce08113c576b03022 397 SUPERFAMILY SSF103473 7 386 1.57E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS01370 f2d9b37eac3ac47ce08113c576b03022 397 Gene3D G3DSA:1.20.1250.20 2 194 1.7E-14 T 28-03-2018 WM46_RS21200 eb07f3c66b0835a3ba4d14887fb85d33 105 SUPERFAMILY SSF46973 1 100 3.66E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS21200 eb07f3c66b0835a3ba4d14887fb85d33 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 99 4.3E-31 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS21200 eb07f3c66b0835a3ba4d14887fb85d33 105 Gene3D G3DSA:1.20.58.80 2 100 6.6E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS21200 eb07f3c66b0835a3ba4d14887fb85d33 105 PIRSF PIRSF000699 1 104 2.2E-32 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS02945 535fff57b45a3368fc11db230fc469b3 470 Pfam PF13440 Polysaccharide biosynthesis protein 17 317 4.3E-12 T 28-03-2018 WM46_RS02945 535fff57b45a3368fc11db230fc469b3 470 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 334 450 2.5E-9 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain WM46_RS18725 9b1a43aadd606900b191e2355cae4352 82 Pfam PF01402 Ribbon-helix-helix protein, copG family 16 49 6.5E-7 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 WM46_RS18725 9b1a43aadd606900b191e2355cae4352 82 Gene3D G3DSA:1.10.1220.10 7 63 8.7E-14 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS18725 9b1a43aadd606900b191e2355cae4352 82 SUPERFAMILY SSF47598 9 49 6.67E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 Gene3D G3DSA:3.40.50.300 1 173 5.6E-37 T 28-03-2018 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 Pfam PF01202 Shikimate kinase 13 170 2.7E-56 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 PRINTS PR01100 Shikimate kinase family signature 59 67 3.5E-29 T 28-03-2018 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 PRINTS PR01100 Shikimate kinase family signature 98 115 3.5E-29 T 28-03-2018 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 PRINTS PR01100 Shikimate kinase family signature 7 22 3.5E-29 T 28-03-2018 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 PRINTS PR01100 Shikimate kinase family signature 31 44 3.5E-29 T 28-03-2018 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 PRINTS PR01100 Shikimate kinase family signature 77 86 3.5E-29 T 28-03-2018 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 SUPERFAMILY SSF52540 4 170 9.58E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS17780 4a9a7733a5f89a4dab87a39d42e7af14 173 Hamap MF_00109 Shikimate kinase [aroK]. 4 171 29.352 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 WM46_RS15190 317714da7098401d75fb5b2c5041cb66 185 SUPERFAMILY SSF52218 1 177 7.54E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS15190 317714da7098401d75fb5b2c5041cb66 185 Gene3D G3DSA:3.40.50.360 1 181 1.5E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS15190 317714da7098401d75fb5b2c5041cb66 185 Pfam PF02525 Flavodoxin-like fold 3 165 6.2E-33 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS25050 995442a1b7d9c245052c146889b5f76b 454 Gene3D G3DSA:3.30.1850.10 3 111 6.5E-48 T 28-03-2018 IPR027820 Domain of unknown function DUF4478 WM46_RS25050 995442a1b7d9c245052c146889b5f76b 454 Pfam PF11892 Domain of unknown function (DUF3412) 333 452 4.1E-55 T 28-03-2018 IPR021826 Domain of unknown function DUF3412 WM46_RS25050 995442a1b7d9c245052c146889b5f76b 454 SUPERFAMILY SSF102405 119 330 5.65E-42 T 28-03-2018 WM46_RS25050 995442a1b7d9c245052c146889b5f76b 454 Gene3D G3DSA:3.40.50.450 124 452 1.2E-101 T 28-03-2018 WM46_RS25050 995442a1b7d9c245052c146889b5f76b 454 Pfam PF03641 Possible lysine decarboxylase 190 329 7.4E-33 T 28-03-2018 IPR031100 LOG family WM46_RS25050 995442a1b7d9c245052c146889b5f76b 454 Pfam PF14793 Domain of unknown function (DUF4478) 4 110 2.0E-46 T 28-03-2018 IPR027820 Domain of unknown function DUF4478 WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 Gene3D G3DSA:3.40.50.720 2 160 1.1E-40 T 28-03-2018 WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 189 0.0041 T 28-03-2018 WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 5 243 6.0E-138 T 28-03-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.5E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 242 2.1E-56 T 28-03-2018 WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 SUPERFAMILY SSF51735 3 242 1.82E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 Gene3D G3DSA:3.40.50.720 161 242 9.1E-20 T 28-03-2018 WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS18315 9d69d2844fd18db53dfe4c6a6bcb5d77 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS11550 10a2e3e5a7b2c99fa20776232a850845 407 Gene3D G3DSA:3.40.50.620 4 237 3.2E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS11550 10a2e3e5a7b2c99fa20776232a850845 407 SUPERFAMILY SSF52402 10 232 1.21E-42 T 28-03-2018 WM46_RS11550 10a2e3e5a7b2c99fa20776232a850845 407 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 30 234 4.2E-17 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 WM46_RS11550 10a2e3e5a7b2c99fa20776232a850845 407 Pfam PF11922 Domain of unknown function (DUF3440) 353 384 1.3E-7 T 28-03-2018 IPR021845 Protein of unknown function DUF3440 WM46_RS11550 10a2e3e5a7b2c99fa20776232a850845 407 Pfam PF11922 Domain of unknown function (DUF3440) 237 339 1.1E-23 T 28-03-2018 IPR021845 Protein of unknown function DUF3440 WM46_RS05590 c7d4294a21aaa08294d39730b07f48ce 231 SUPERFAMILY SSF110857 47 160 3.27E-10 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like WM46_RS05590 c7d4294a21aaa08294d39730b07f48ce 231 Gene3D G3DSA:3.10.490.10 32 219 4.9E-33 T 28-03-2018 WM46_RS05590 c7d4294a21aaa08294d39730b07f48ce 231 Pfam PF04752 ChaC-like protein 47 214 2.0E-53 T 28-03-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 Reactome: R-HSA-174403 WM46_RS11685 09394071d28e9e02adbd295eaa5121c9 472 Gene3D G3DSA:3.40.50.1070 32 178 4.4E-5 T 28-03-2018 WM46_RS11685 09394071d28e9e02adbd295eaa5121c9 472 Pfam PF02952 L-fucose isomerase, C-terminal domain 343 468 2.4E-35 T 28-03-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 WM46_RS11685 09394071d28e9e02adbd295eaa5121c9 472 SUPERFAMILY SSF53743 6 322 4.97E-60 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 WM46_RS04385 354e2fc7b8d8f3ebe9e99f6e8b5c7847 220 Pfam PF00929 Exonuclease 4 147 6.0E-15 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS04385 354e2fc7b8d8f3ebe9e99f6e8b5c7847 220 Gene3D G3DSA:3.30.420.10 1 161 1.2E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS04385 354e2fc7b8d8f3ebe9e99f6e8b5c7847 220 SMART SM00479 1 156 1.3E-37 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III WM46_RS04385 354e2fc7b8d8f3ebe9e99f6e8b5c7847 220 SUPERFAMILY SSF53098 4 182 3.8E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS00430 836c0c8b2a1c65f5c1a447650f1abde9 86 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS00430 836c0c8b2a1c65f5c1a447650f1abde9 86 Gene3D G3DSA:3.30.70.20 1 20 1.1E-4 T 28-03-2018 WM46_RS00430 836c0c8b2a1c65f5c1a447650f1abde9 86 Gene3D G3DSA:3.30.70.20 45 84 0.1 T 28-03-2018 WM46_RS00430 836c0c8b2a1c65f5c1a447650f1abde9 86 SUPERFAMILY SSF54862 5 71 1.23E-17 T 28-03-2018 WM46_RS00430 836c0c8b2a1c65f5c1a447650f1abde9 86 Pfam PF12838 4Fe-4S dicluster domain 8 55 3.9E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS00430 836c0c8b2a1c65f5c1a447650f1abde9 86 Gene3D G3DSA:3.30.70.20 21 44 2.7E-8 T 28-03-2018 WM46_RS07675 82720759507561d566b424fcc151c7a8 211 Pfam PF15977 Winged helix-turn-helix DNA binding 150 209 3.3E-20 T 28-03-2018 WM46_RS21785 be179e1b8ec68ec4342d57f8f05a50ef 318 TIGRFAM TIGR03148 cyt_nit_nrfD: cytochrome c nitrite reductase, NrfD subunit 5 318 1.3E-143 T 28-03-2018 IPR017566 NrfD WM46_RS21785 be179e1b8ec68ec4342d57f8f05a50ef 318 Pfam PF03916 Polysulphide reductase, NrfD 6 318 3.0E-103 T 28-03-2018 IPR005614 NrfD family WM46_RS21785 be179e1b8ec68ec4342d57f8f05a50ef 318 Gene3D G3DSA:1.20.1630.10 6 318 5.1E-56 T 28-03-2018 WM46_RS21430 4e896cd0c12d21214f38c3fb26938ec2 317 SUPERFAMILY SSF46689 9 56 8.42E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS21430 4e896cd0c12d21214f38c3fb26938ec2 317 Gene3D G3DSA:1.10.10.60 3 54 6.7E-20 T 28-03-2018 WM46_RS21430 4e896cd0c12d21214f38c3fb26938ec2 317 Pfam PF13936 Helix-turn-helix domain 14 47 1.5E-8 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain WM46_RS21430 4e896cd0c12d21214f38c3fb26938ec2 317 SUPERFAMILY SSF100950 64 317 7.95E-65 T 28-03-2018 WM46_RS21430 4e896cd0c12d21214f38c3fb26938ec2 317 Gene3D G3DSA:3.40.50.1360 55 317 1.3E-33 T 28-03-2018 WM46_RS21430 4e896cd0c12d21214f38c3fb26938ec2 317 Pfam PF04198 Putative sugar-binding domain 61 317 1.5E-76 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 WM46_RS17810 f2e606112d621a72b2c4eb026e2f84da 259 SUPERFAMILY SSF53067 35 164 2.98E-5 T 28-03-2018 WM46_RS17810 f2e606112d621a72b2c4eb026e2f84da 259 Gene3D G3DSA:3.30.420.40 6 155 4.7E-4 T 28-03-2018 WM46_RS06765 41699e3f835bf1f474152858d483a37d 146 Gene3D G3DSA:3.90.1590.10 1 142 1.3E-21 T 28-03-2018 WM46_RS06765 41699e3f835bf1f474152858d483a37d 146 SUPERFAMILY SSF51316 3 129 2.3E-26 T 28-03-2018 IPR011057 Mss4-like WM46_RS06765 41699e3f835bf1f474152858d483a37d 146 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 114 2.4E-10 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 WM46_RS06085 1acb682b72f7a63cfbf2c4e803365dd6 119 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 7 119 4.3E-39 T 28-03-2018 IPR014320 Phage shock protein, PspC WM46_RS06085 1acb682b72f7a63cfbf2c4e803365dd6 119 Pfam PF04024 PspC domain 8 65 1.5E-15 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal WM46_RS06315 a300d940950d975663faec5859f512dc 136 SUPERFAMILY SSF51316 1 122 1.03E-31 T 28-03-2018 IPR011057 Mss4-like WM46_RS06315 a300d940950d975663faec5859f512dc 136 Gene3D G3DSA:3.90.1590.10 1 118 4.7E-23 T 28-03-2018 WM46_RS06315 a300d940950d975663faec5859f512dc 136 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 29 108 2.2E-8 T 28-03-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 WM46_RS22415 4d6326112f8dfedd5078b1cbb294edbb 87 SUPERFAMILY SSF143011 1 82 8.24E-6 T 28-03-2018 IPR035095 Toxin RelE-like domain WM46_RS22415 4d6326112f8dfedd5078b1cbb294edbb 87 Gene3D G3DSA:3.30.2310.20 1 86 1.1E-4 T 28-03-2018 WM46_RS22415 4d6326112f8dfedd5078b1cbb294edbb 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 86 4.9E-8 T 28-03-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 278 289 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 Gene3D G3DSA:3.30.70.20 254 282 1.0E-8 T 28-03-2018 WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 SUPERFAMILY SSF54862 109 129 9.57E-22 T 28-03-2018 WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 SUPERFAMILY SSF54862 181 291 9.57E-22 T 28-03-2018 WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 Gene3D G3DSA:3.30.70.20 221 253 8.2E-10 T 28-03-2018 WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 Pfam PF12801 4Fe-4S binding domain 202 246 2.3E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 Pfam PF12801 4Fe-4S binding domain 97 142 2.6E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS09250 cafc4cc333b4f4618e7bc5e02e917cbd 359 Gene3D G3DSA:1.10.1060.10 283 318 0.01 T 28-03-2018 WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 SUPERFAMILY SSF51735 10 252 6.02E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 6 253 1.4E-130 T 28-03-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 1.1E-58 T 28-03-2018 WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 Gene3D G3DSA:3.40.50.720 48 253 7.6E-61 T 28-03-2018 WM46_RS08095 49c85970246e3996b420454e8c3a3754 253 Gene3D G3DSA:3.40.50.720 3 47 1.2E-6 T 28-03-2018 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 Pfam PF01555 DNA methylase 23 319 5.4E-34 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 Gene3D G3DSA:3.40.50.150 1 349 7.6E-65 T 28-03-2018 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 281 299 4.6E-27 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 22 36 4.6E-27 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 50 70 4.6E-27 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 262 279 4.6E-27 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 304 324 4.6E-27 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 SUPERFAMILY SSF53335 237 324 1.42E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 SUPERFAMILY SSF53335 3 134 1.42E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS03230 4159ced7b35fd80edb5f4a11dcdcbcf9 351 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 26 32 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS21895 7cbb8122acd20242a0818672e10a3747 262 SUPERFAMILY SSF52540 3 237 7.43E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21895 7cbb8122acd20242a0818672e10a3747 262 SMART SM00382 29 229 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS21895 7cbb8122acd20242a0818672e10a3747 262 Pfam PF00005 ABC transporter 20 181 7.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21895 7cbb8122acd20242a0818672e10a3747 262 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 4 250 1.2E-102 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 WM46_RS21895 7cbb8122acd20242a0818672e10a3747 262 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS21895 7cbb8122acd20242a0818672e10a3747 262 Gene3D G3DSA:3.40.50.300 1 261 3.0E-60 T 28-03-2018 WM46_RS16950 eff9785fb543be2e63d21ce1fd976150 284 Pfam PF03668 P-loop ATPase protein family 1 282 6.9E-147 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 WM46_RS16950 eff9785fb543be2e63d21ce1fd976150 284 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 281 41.092 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 WM46_RS16950 eff9785fb543be2e63d21ce1fd976150 284 Gene3D G3DSA:3.40.50.300 1 152 7.1E-12 T 28-03-2018 WM46_RS16950 eff9785fb543be2e63d21ce1fd976150 284 SUPERFAMILY SSF52540 2 151 1.5E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS16950 eff9785fb543be2e63d21ce1fd976150 284 PIRSF PIRSF005052 1 284 3.7E-115 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 WM46_RS07345 5d1a3bb360b2c70687ff433734260412 460 Pfam PF13520 Amino acid permease 5 441 2.2E-76 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS07345 5d1a3bb360b2c70687ff433734260412 460 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 3 459 5.8E-183 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 WM46_RS07345 5d1a3bb360b2c70687ff433734260412 460 PIRSF PIRSF006060 1 459 2.1E-46 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS13860 c4306c3c9aed540e44a65e7ed772b18f 139 Pfam PF00472 RF-1 domain 7 132 1.0E-25 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM46_RS13860 c4306c3c9aed540e44a65e7ed772b18f 139 SUPERFAMILY SSF75620 7 113 5.1E-14 T 28-03-2018 WM46_RS13860 c4306c3c9aed540e44a65e7ed772b18f 139 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 WM46_RS13860 c4306c3c9aed540e44a65e7ed772b18f 139 Gene3D G3DSA:3.30.160.20 1 139 3.7E-42 T 28-03-2018 WM46_RS00390 5c302a53567cb49f54adb3af956676a4 159 PIRSF PIRSF004923 1 151 8.8E-42 T 28-03-2018 IPR026268 Protein RseC WM46_RS00390 5c302a53567cb49f54adb3af956676a4 159 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 139 1.6E-33 T 28-03-2018 IPR007359 Positive regulator of sigma(E), RseC/MucC WM46_RS17220 b9785d2d5b5e713034410935a3e88aba 146 Pfam PF07681 DoxX 21 99 1.9E-15 T 28-03-2018 IPR032808 DoxX family WM46_RS24040 cca9ec78a7d4e3bd6bbd38e305c906a8 343 Pfam PF08468 Methyltransferase small domain N-terminal 8 162 5.0E-57 T 28-03-2018 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS24040 cca9ec78a7d4e3bd6bbd38e305c906a8 343 Pfam PF05175 Methyltransferase small domain 167 333 1.6E-60 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 WM46_RS24040 cca9ec78a7d4e3bd6bbd38e305c906a8 343 SUPERFAMILY SSF53335 154 315 1.42E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS24040 cca9ec78a7d4e3bd6bbd38e305c906a8 343 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 4 336 45.296 T 28-03-2018 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 WM46_RS24040 cca9ec78a7d4e3bd6bbd38e305c906a8 343 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 265 271 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS24040 cca9ec78a7d4e3bd6bbd38e305c906a8 343 Gene3D G3DSA:3.40.50.150 159 343 8.6E-35 T 28-03-2018 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 Gene3D G3DSA:2.20.25.90 64 157 1.8E-13 T 28-03-2018 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 Pfam PF00384 Molybdopterin oxidoreductase 242 683 1.3E-15 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 SUPERFAMILY SSF53706 137 865 6.81E-114 T 28-03-2018 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 SUPERFAMILY SSF53706 72 110 6.81E-114 T 28-03-2018 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 SUPERFAMILY SSF50692 875 996 4.52E-23 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 Pfam PF01568 Molydopterin dinucleotide binding domain 889 995 2.6E-12 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 Gene3D G3DSA:3.40.50.740 454 790 9.2E-32 T 28-03-2018 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 Gene3D G3DSA:2.40.40.20 848 1023 1.2E-23 T 28-03-2018 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 SMART SM00926 71 153 8.3E-16 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS07785 311e42cae6a0ca9ee6894a5aa024d9fc 1023 Gene3D G3DSA:3.40.50.740 158 360 9.5E-23 T 28-03-2018 WM46_RS25230 aa0314c7948ecf7f3b99bdb07b39993d 345 SUPERFAMILY SSF53187 37 316 1.01E-36 T 28-03-2018 WM46_RS25230 aa0314c7948ecf7f3b99bdb07b39993d 345 Gene3D G3DSA:3.40.630.10 28 331 2.8E-40 T 28-03-2018 WM46_RS25230 aa0314c7948ecf7f3b99bdb07b39993d 345 Pfam PF04389 Peptidase family M28 100 328 2.2E-33 T 28-03-2018 IPR007484 Peptidase M28 WM46_RS07610 2f7742eb0297f25b1d76cd79a73d0242 388 SUPERFAMILY SSF103473 6 379 4.71E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07610 2f7742eb0297f25b1d76cd79a73d0242 388 Gene3D G3DSA:1.20.1250.20 191 384 3.4E-17 T 28-03-2018 WM46_RS07610 2f7742eb0297f25b1d76cd79a73d0242 388 Gene3D G3DSA:1.20.1250.20 3 190 2.4E-26 T 28-03-2018 WM46_RS07610 2f7742eb0297f25b1d76cd79a73d0242 388 Pfam PF07690 Major Facilitator Superfamily 10 322 6.3E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS11160 ed9eb7561fed4c8341015ef29566e790 97 Pfam PF01402 Ribbon-helix-helix protein, copG family 52 88 3.5E-8 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 WM46_RS11160 ed9eb7561fed4c8341015ef29566e790 97 Gene3D G3DSA:1.10.1220.10 50 90 8.9E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS09650 e6654fec44b0695964abf9df2ec576be 150 ProDom PD033720 UPF0268 YCBG DEHYDROGENASE PM0482 PBPRA1775 PLU1774 YPO1433/Y2737/YP0877 VV1664 HI1323 HD0178 1 131 7.0E-68 T 28-03-2018 IPR009390 Macrodomain Ter protein, MatP GO:0043565 WM46_RS09650 e6654fec44b0695964abf9df2ec576be 150 Pfam PF17414 MatP C-terminal ribbon-helix-helix domain 88 147 1.3E-30 T 28-03-2018 IPR035375 MatP, C-terminal ribbon-helix-helix domain WM46_RS09650 e6654fec44b0695964abf9df2ec576be 150 Gene3D G3DSA:1.10.3990.20 74 139 5.9E-5 T 28-03-2018 WM46_RS09650 e6654fec44b0695964abf9df2ec576be 150 Pfam PF06303 MatP N-terminal domain 2 85 1.6E-43 T 28-03-2018 IPR035087 MatP, N-terminal WM46_RS09650 e6654fec44b0695964abf9df2ec576be 150 Hamap MF_01073 Macrodomain Ter protein [matP]. 1 148 30.937 T 28-03-2018 IPR009390 Macrodomain Ter protein, MatP GO:0043565 WM46_RS12705 1a5c88c608baecae436ece5249bbb4d2 196 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 5 183 2.0E-61 T 28-03-2018 IPR006287 Protein DJ-1 WM46_RS12705 1a5c88c608baecae436ece5249bbb4d2 196 Gene3D G3DSA:3.40.50.880 1 190 7.8E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS12705 1a5c88c608baecae436ece5249bbb4d2 196 Pfam PF01965 DJ-1/PfpI family 4 170 3.1E-45 T 28-03-2018 IPR002818 DJ-1/PfpI WM46_RS12705 1a5c88c608baecae436ece5249bbb4d2 196 SUPERFAMILY SSF52317 5 188 7.94E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 PIRSF PIRSF038996 1 172 2.1E-55 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 SUPERFAMILY SSF52218 1 168 1.54E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 Pfam PF00258 Flavodoxin 5 160 4.4E-27 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 TIGRFAM TIGR01752 flav_long: flavodoxin 2 168 4.8E-69 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 Gene3D G3DSA:3.40.50.360 76 173 3.9E-17 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS24255 da87c8640b1fa8e011d186fddc5e3e26 173 Gene3D G3DSA:3.40.50.360 1 75 6.8E-15 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 Gene3D G3DSA:3.20.20.70 4 363 4.3E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 Pfam PF13186 Iron-sulfur cluster-binding domain 247 306 1.3E-6 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 Pfam PF04055 Radical SAM superfamily 6 165 1.8E-7 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 246 325 1.9E-17 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 SUPERFAMILY SSF102114 7 316 6.93E-40 T 28-03-2018 WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 152 366 2.0E-46 T 28-03-2018 WM46_RS19755 8bb753bcc7c275965d4cc22387ed2aca 367 TIGRFAM TIGR03942 sulfatase_rSAM: anaerobic sulfatase maturase 1 348 1.1E-138 T 28-03-2018 IPR023867 Anaerobic sulphatase maturase, radical SAM GO:0016491 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 Pfam PF00239 Resolvase, N terminal domain 4 137 7.3E-39 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 Gene3D G3DSA:1.10.10.60 139 183 3.6E-11 T 28-03-2018 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 SUPERFAMILY SSF46689 141 181 2.42E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 ProSitePatterns PS00398 Site-specific recombinases signature 2. 58 70 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 Pfam PF02796 Helix-turn-helix domain of resolvase 141 181 1.4E-9 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 SMART SM00857 3 139 1.5E-46 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 Gene3D G3DSA:3.40.50.1390 1 107 8.1E-35 T 28-03-2018 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 SUPERFAMILY SSF53041 1 138 6.15E-42 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 WM46_RS22355 8568efe0437d107381ea4cd7472504c5 190 Gene3D G3DSA:1.20.5.40 108 137 1.4E-13 T 28-03-2018 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 SUPERFAMILY SSF48452 116 246 6.54E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 Pfam PF00085 Thioredoxin 7 108 3.2E-18 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 Gene3D G3DSA:1.25.40.10 197 284 3.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 Pfam PF14561 Tetratricopeptide repeat 195 284 1.0E-27 T 28-03-2018 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 SUPERFAMILY SSF52833 2 112 8.89E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 Pfam PF14559 Tetratricopeptide repeat 124 190 9.3E-23 T 28-03-2018 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 Gene3D G3DSA:1.25.40.10 125 196 7.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS12275 06202c92db43eeb2aaf4bc0de946d9be 284 Gene3D G3DSA:3.40.30.10 1 124 1.7E-28 T 28-03-2018 WM46_RS19220 f5c7d72c1cf7d1df18faa102fd910268 225 Gene3D G3DSA:3.40.630.30 88 225 8.8E-16 T 28-03-2018 WM46_RS19220 f5c7d72c1cf7d1df18faa102fd910268 225 Hamap MF_02027 dTDP-fucosamine acetyltransferase [wecD]. 44 225 43.656 T 28-03-2018 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 KEGG: 00071+2.3.1.21|MetaCyc: PWY-6111|MetaCyc: PWY-7315 WM46_RS19220 f5c7d72c1cf7d1df18faa102fd910268 225 SUPERFAMILY SSF55729 42 219 5.85E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS19220 f5c7d72c1cf7d1df18faa102fd910268 225 Pfam PF00583 Acetyltransferase (GNAT) family 137 209 1.5E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS19220 f5c7d72c1cf7d1df18faa102fd910268 225 TIGRFAM TIGR02382 wecD_rffC: TDP-D-fucosamine acetyltransferase 44 225 7.7E-88 T 28-03-2018 IPR012752 dTDP-fucosamine acetyltransferase WecD GO:0008080|GO:0009246 KEGG: 00071+2.3.1.21|MetaCyc: PWY-6111|MetaCyc: PWY-7315 WM46_RS21915 a6db64ce2c38d6e6333345d0396f1a87 296 Pfam PF13990 YjcZ-like protein 21 289 1.2E-128 T 28-03-2018 IPR025599 YjcZ-like protein WM46_RS18730 b7f499b5cadaee478c7f9f85fdf0c90d 302 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 147 159 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site WM46_RS18730 b7f499b5cadaee478c7f9f85fdf0c90d 302 Gene3D G3DSA:3.40.50.1820 2 302 3.5E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS18730 b7f499b5cadaee478c7f9f85fdf0c90d 302 Pfam PF07859 alpha/beta hydrolase fold 75 280 4.0E-66 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 WM46_RS18730 b7f499b5cadaee478c7f9f85fdf0c90d 302 SUPERFAMILY SSF53474 25 297 1.15E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23700 98b116f62e8a018cc0394def7c4c0db9 116 Gene3D G3DSA:2.60.120.10 3 114 1.2E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS23700 98b116f62e8a018cc0394def7c4c0db9 116 Pfam PF07883 Cupin domain 30 96 2.6E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS23700 98b116f62e8a018cc0394def7c4c0db9 116 SUPERFAMILY SSF51182 27 106 7.91E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS14210 6e38bff7ca1ce5bf0441ddaf8551bb67 327 Gene3D G3DSA:3.40.718.10 2 327 5.4E-126 T 28-03-2018 WM46_RS14210 6e38bff7ca1ce5bf0441ddaf8551bb67 327 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 327 9.0E-112 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 WM46_RS14210 6e38bff7ca1ce5bf0441ddaf8551bb67 327 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 327 35.804 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 WM46_RS14210 6e38bff7ca1ce5bf0441ddaf8551bb67 327 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 39 323 6.8E-102 T 28-03-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 WM46_RS14210 6e38bff7ca1ce5bf0441ddaf8551bb67 327 SUPERFAMILY SSF53659 4 327 3.78E-106 T 28-03-2018 WM46_RS12645 77123a59698b3a36b0dea572a225e9fb 105 SUPERFAMILY SSF82657 1 89 4.71E-30 T 28-03-2018 IPR002634 BolA protein WM46_RS12645 77123a59698b3a36b0dea572a225e9fb 105 Pfam PF01722 BolA-like protein 11 84 8.2E-28 T 28-03-2018 IPR002634 BolA protein WM46_RS12645 77123a59698b3a36b0dea572a225e9fb 105 Gene3D G3DSA:3.30.300.90 1 91 4.5E-27 T 28-03-2018 WM46_RS12645 77123a59698b3a36b0dea572a225e9fb 105 PIRSF PIRSF003113 1 100 1.3E-32 T 28-03-2018 IPR002634 BolA protein WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 Gene3D G3DSA:1.10.10.10 1 132 2.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 SUPERFAMILY SSF46785 3 135 1.99E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 5.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 5.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 5.3E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 SMART SM00347 22 122 1.3E-25 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 Pfam PF01047 MarR family 29 86 5.6E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 61 95 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site WM46_RS13330 8f10186961e80641bcfdbaca77999c73 148 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 4 133 3.9E-57 T 28-03-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 WM46_RS12715 1ab82a6bb3b14174f5e875af9ab2c42a 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site WM46_RS12715 1ab82a6bb3b14174f5e875af9ab2c42a 183 Pfam PF13247 4Fe-4S dicluster domain 52 145 2.7E-25 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain WM46_RS12715 1ab82a6bb3b14174f5e875af9ab2c42a 183 SUPERFAMILY SSF54862 3 183 6.8E-60 T 28-03-2018 WM46_RS12715 1ab82a6bb3b14174f5e875af9ab2c42a 183 Gene3D G3DSA:3.30.70.20 4 72 6.4E-14 T 28-03-2018 WM46_RS12715 1ab82a6bb3b14174f5e875af9ab2c42a 183 Gene3D G3DSA:3.30.70.20 73 109 6.1E-18 T 28-03-2018 WM46_RS12715 1ab82a6bb3b14174f5e875af9ab2c42a 183 Gene3D G3DSA:3.30.70.20 110 183 8.5E-16 T 28-03-2018 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 Gene3D G3DSA:3.20.20.70 259 452 9.3E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 50 68 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 254 35.469 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 257 447 5.3E-63 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 Gene3D G3DSA:3.20.20.70 1 258 3.7E-62 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 251 2.3E-98 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 SUPERFAMILY SSF51366 257 450 4.71E-59 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 SUPERFAMILY SSF51366 1 251 1.17E-84 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS05840 72aeb45f067860b9d98eddc899ee9493 452 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 255 452 31.448 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 WM46_RS25315 028820a6eeacc0402d1f0e57519a90fc 78 Gene3D G3DSA:2.20.25.10 2 41 2.9E-4 T 28-03-2018 WM46_RS08405 8a55373ad028a76ff6b1de64f43efb8d 169 Pfam PF04463 Protein of unknown function (DUF523) 5 150 9.6E-39 T 28-03-2018 IPR007553 Domain of unknown function DUF523 WM46_RS13850 5615365b5e3099667d52a39fb0461cdb 274 Gene3D G3DSA:3.90.1720.10 61 257 2.9E-26 T 28-03-2018 WM46_RS13850 5615365b5e3099667d52a39fb0461cdb 274 SUPERFAMILY SSF54001 64 160 3.24E-26 T 28-03-2018 WM46_RS13850 5615365b5e3099667d52a39fb0461cdb 274 SUPERFAMILY SSF54001 201 263 3.24E-26 T 28-03-2018 WM46_RS13850 5615365b5e3099667d52a39fb0461cdb 274 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 65 156 5.6E-7 T 28-03-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family WM46_RS02950 430344fbc0be1d31cecd184b2d311c64 416 SUPERFAMILY SSF53756 176 308 4.71E-6 T 28-03-2018 WM46_RS05225 a9b7be4f5f5c1ae4d24775ea472e7ad7 210 SUPERFAMILY SSF101473 2 205 4.97E-58 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM46_RS05225 a9b7be4f5f5c1ae4d24775ea472e7ad7 210 SMART SM01120 32 206 1.3E-80 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM46_RS05225 a9b7be4f5f5c1ae4d24775ea472e7ad7 210 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 9 205 3.4E-81 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 WM46_RS05225 a9b7be4f5f5c1ae4d24775ea472e7ad7 210 Pfam PF02734 DAK2 domain 32 205 3.0E-55 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 WM46_RS09260 5baf71c315e736c81d664914331e5d18 384 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 374 2.4E-112 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS09260 5baf71c315e736c81d664914331e5d18 384 Gene3D G3DSA:1.20.1090.10 183 384 3.7E-52 T 28-03-2018 WM46_RS09260 5baf71c315e736c81d664914331e5d18 384 SUPERFAMILY SSF56796 3 382 2.88E-116 T 28-03-2018 WM46_RS09260 5baf71c315e736c81d664914331e5d18 384 Gene3D G3DSA:3.40.50.1970 9 182 9.0E-51 T 28-03-2018 WM46_RS06480 21dd102870e265c6c4de4114a650e949 326 Gene3D G3DSA:2.160.10.10 178 307 1.4E-11 T 28-03-2018 WM46_RS06480 21dd102870e265c6c4de4114a650e949 326 Gene3D G3DSA:2.160.10.10 44 152 7.1E-13 T 28-03-2018 WM46_RS06480 21dd102870e265c6c4de4114a650e949 326 SUPERFAMILY SSF51161 5 312 1.53E-59 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS04615 199255e62e50117fea0a9373aadc4efa 96 Pfam PF07102 Protein of unknown function (DUF1364) 3 92 5.3E-42 T 28-03-2018 IPR010774 Protein of unknown function DUF1364 WM46_RS04615 199255e62e50117fea0a9373aadc4efa 96 Gene3D G3DSA:3.30.50.20 19 92 8.2E-28 T 28-03-2018 WM46_RS13155 69722838eb12bc4e5780f7488065919f 203 SUPERFAMILY SSF51161 7 197 2.36E-54 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS13155 69722838eb12bc4e5780f7488065919f 203 SMART SM01266 6 60 1.0E-14 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 WM46_RS13155 69722838eb12bc4e5780f7488065919f 203 Pfam PF12464 Maltose acetyltransferase 8 59 7.6E-12 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 WM46_RS13155 69722838eb12bc4e5780f7488065919f 203 Gene3D G3DSA:2.160.10.10 4 200 1.7E-49 T 28-03-2018 WM46_RS13155 69722838eb12bc4e5780f7488065919f 203 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 7.8E-12 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS13155 69722838eb12bc4e5780f7488065919f 203 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 WM46_RS12465 bdc3e71ae9a577eaa52cd35b2eadaaa7 46 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 16.354 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS12465 bdc3e71ae9a577eaa52cd35b2eadaaa7 46 Pfam PF00444 Ribosomal protein L36 1 41 3.3E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS12465 bdc3e71ae9a577eaa52cd35b2eadaaa7 46 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS12465 bdc3e71ae9a577eaa52cd35b2eadaaa7 46 SUPERFAMILY SSF57840 7 41 9.81E-14 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS12465 bdc3e71ae9a577eaa52cd35b2eadaaa7 46 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 9 41 1.6E-8 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS06900 470232b14c3d218c671ae0828f718a45 1763 Gene3D G3DSA:1.20.120.20 1202 1385 0.0064 T 28-03-2018 WM46_RS06900 470232b14c3d218c671ae0828f718a45 1763 Gene3D G3DSA:1.20.1170.10 771 1191 2.3E-4 T 28-03-2018 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 PIRSF PIRSF002161 1 179 4.8E-67 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 5.4E-41 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 Gene3D G3DSA:3.30.1440.10 1 179 3.6E-81 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 SUPERFAMILY SSF55282 4 179 1.88E-79 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 Pfam PF00281 Ribosomal protein L5 24 80 1.1E-28 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17485 dd56b1a1b3dec92037ad5913650793f9 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.826 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS22385 7226c07d97cb5b6047ec7d4a0de0c804 327 Pfam PF00535 Glycosyl transferase family 2 11 171 4.7E-32 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS22385 7226c07d97cb5b6047ec7d4a0de0c804 327 SUPERFAMILY SSF53448 9 232 4.17E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS22385 7226c07d97cb5b6047ec7d4a0de0c804 327 Gene3D G3DSA:3.90.550.10 4 231 7.7E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS22385 7226c07d97cb5b6047ec7d4a0de0c804 327 Hamap MF_01164 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [arnC]. 2 326 61.117 T 28-03-2018 IPR022857 Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase GO:0016780 KEGG: 00520+2.4.2.53 WM46_RS21425 161818160858d355e668127cd3c68e67 268 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 196 0.0024 T 28-03-2018 WM46_RS21425 161818160858d355e668127cd3c68e67 268 Pfam PF00106 short chain dehydrogenase 10 205 4.7E-58 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 Gene3D G3DSA:3.40.50.720 6 267 9.2E-63 T 28-03-2018 WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 9.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 9.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 9.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 9.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 9.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 9.6E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS21425 161818160858d355e668127cd3c68e67 268 SUPERFAMILY SSF51735 8 266 2.65E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS21425 161818160858d355e668127cd3c68e67 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS07570 44996cfcd697b1f34eae8d14c5abf80d 841 SUPERFAMILY SSF141729 60 174 1.44E-22 T 28-03-2018 WM46_RS07570 44996cfcd697b1f34eae8d14c5abf80d 841 Pfam PF00577 Outer membrane usher protein 198 750 5.0E-168 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS07570 44996cfcd697b1f34eae8d14c5abf80d 841 Pfam PF13953 PapC C-terminal domain 763 822 8.0E-19 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS07570 44996cfcd697b1f34eae8d14c5abf80d 841 Pfam PF13954 PapC N-terminal domain 36 183 2.5E-36 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS07105 618a0331d7bb834591840859a95ea0bb 265 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 24 265 6.0E-112 T 28-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD WM46_RS07105 618a0331d7bb834591840859a95ea0bb 265 SUPERFAMILY SSF52540 22 263 1.01E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07105 618a0331d7bb834591840859a95ea0bb 265 Pfam PF00005 ABC transporter 40 194 5.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS07105 618a0331d7bb834591840859a95ea0bb 265 Gene3D G3DSA:3.40.50.300 9 264 7.2E-59 T 28-03-2018 WM46_RS07105 618a0331d7bb834591840859a95ea0bb 265 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 243 264 2.9E-7 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal WM46_RS06550 20fea55f5875690746e848499c87fa39 469 Gene3D G3DSA:3.40.640.10 120 369 6.9E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS06550 20fea55f5875690746e848499c87fa39 469 Pfam PF00155 Aminotransferase class I and II 145 446 2.0E-32 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS06550 20fea55f5875690746e848499c87fa39 469 SUPERFAMILY SSF46785 2 70 1.09E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06550 20fea55f5875690746e848499c87fa39 469 Gene3D G3DSA:1.10.10.10 1 68 7.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS06550 20fea55f5875690746e848499c87fa39 469 SMART SM00345 7 66 2.2E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS06550 20fea55f5875690746e848499c87fa39 469 SUPERFAMILY SSF53383 91 466 1.6E-92 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS06550 20fea55f5875690746e848499c87fa39 469 Gene3D G3DSA:3.90.1150.10 370 468 1.5E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS06550 20fea55f5875690746e848499c87fa39 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 5.0E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 SUPERFAMILY SSF103473 251 452 1.22E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 SUPERFAMILY SSF103473 9 195 1.22E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 Gene3D G3DSA:1.20.1250.20 13 202 1.2E-28 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 Gene3D G3DSA:1.20.1250.20 262 457 2.0E-24 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 3.6E-9 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 3.6E-9 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 3.6E-9 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 305 329 3.6E-9 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 PRINTS PR01036 Tetracycline resistance protein TetB signature 403 422 3.6E-9 T 28-03-2018 WM46_RS04890 d4b02dfc7dcf9e9f7b78f021988280fa 457 Pfam PF07690 Major Facilitator Superfamily 22 412 1.4E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS14415 c916fae1f8ce669e7c1b73afbe0fcefc 121 Pfam PF04999 Cell division protein FtsL 25 119 1.1E-35 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 WM46_RS14415 c916fae1f8ce669e7c1b73afbe0fcefc 121 Hamap MF_00910 Cell division protein FtsL [ftsL]. 35 118 16.794 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 WM46_RS14415 c916fae1f8ce669e7c1b73afbe0fcefc 121 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 36 118 7.1E-29 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 Gene3D G3DSA:1.10.10.10 1 85 4.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 Pfam PF03466 LysR substrate binding domain 92 292 2.0E-42 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 SUPERFAMILY SSF46785 1 85 2.57E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 SUPERFAMILY SSF53850 91 322 3.26E-46 T 28-03-2018 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 Gene3D G3DSA:3.40.190.10 91 180 3.9E-20 T 28-03-2018 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 6.0E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 Gene3D G3DSA:3.40.190.10 181 254 5.7E-23 T 28-03-2018 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 Gene3D G3DSA:3.40.190.10 255 324 0.011 T 28-03-2018 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS05905 272c1bcc8afc63c9d6464162556d11ad 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS20065 c9abe505d1ea59203286929f0c5aa6a4 401 Pfam PF03616 Sodium/glutamate symporter 2 366 5.0E-161 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 WM46_RS20065 c9abe505d1ea59203286929f0c5aa6a4 401 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 2 397 2.5E-199 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 WM46_RS20065 c9abe505d1ea59203286929f0c5aa6a4 401 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 2 397 24.652 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 WM46_RS04900 c5474fd6277f33b8b561d11c9b1c3b2a 79 Pfam PF13996 YobH-like protein 2 71 5.0E-39 T 28-03-2018 IPR025611 YobH-like protein WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 Pfam PF00206 Lyase 28 285 1.1E-36 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 Gene3D G3DSA:1.10.275.10 3 103 1.9E-13 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 Gene3D G3DSA:1.20.200.10 104 361 1.4E-56 T 28-03-2018 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 SMART SM00998 362 441 1.4E-25 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 Pfam PF10397 Adenylosuccinate lyase C-terminus 363 438 2.2E-18 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 SUPERFAMILY SSF48557 17 444 2.2E-94 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 ProSitePatterns PS00163 Fumarate lyases signature. 274 283 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00149 Fumarate lyase superfamily signature 274 290 2.7E-15 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00149 Fumarate lyase superfamily signature 144 162 2.7E-15 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00149 Fumarate lyase superfamily signature 99 117 2.7E-15 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00149 Fumarate lyase superfamily signature 229 256 2.7E-15 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 Gene3D G3DSA:1.10.40.30 362 440 1.5E-20 T 28-03-2018 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00145 Argininosuccinate lyase family signature 274 290 2.4E-11 T 28-03-2018 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00145 Argininosuccinate lyase family signature 139 159 2.4E-11 T 28-03-2018 WM46_RS01285 a15cb9fbc4eb137594afb0b73b762c3c 450 PRINTS PR00145 Argininosuccinate lyase family signature 229 253 2.4E-11 T 28-03-2018 WM46_RS24250 c6d22049bf6b512e1cdf0ac4b0d8805f 135 PIRSF PIRSF020653 1 135 6.9E-74 T 28-03-2018 IPR009883 Inner membrane protein YgfX WM46_RS24250 c6d22049bf6b512e1cdf0ac4b0d8805f 135 ProDom PD083358 MEMBRANE YGFX INNER SIMILAR ECS3768 Y3281 ESCHERICHIA TRANSMEMBRANE YPO0896A STY3202 19 131 1.0E-52 T 28-03-2018 IPR009883 Inner membrane protein YgfX WM46_RS24250 c6d22049bf6b512e1cdf0ac4b0d8805f 135 Pfam PF07254 Membrane-bound toxin component of toxin-antitoxin system 2 128 3.1E-54 T 28-03-2018 IPR009883 Inner membrane protein YgfX WM46_RS11925 970acdc0699e63311df9ebe13d36b7be 397 Gene3D G3DSA:1.20.1250.20 9 197 6.3E-26 T 28-03-2018 WM46_RS11925 970acdc0699e63311df9ebe13d36b7be 397 Gene3D G3DSA:1.20.1250.20 201 395 6.0E-19 T 28-03-2018 WM46_RS11925 970acdc0699e63311df9ebe13d36b7be 397 SUPERFAMILY SSF103473 7 393 8.11E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS11925 970acdc0699e63311df9ebe13d36b7be 397 Pfam PF07690 Major Facilitator Superfamily 24 355 1.4E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS06000 12a20191e3bb33640d029510863463e1 327 Gene3D G3DSA:2.60.40.1090 189 327 3.9E-23 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS06000 12a20191e3bb33640d029510863463e1 327 Pfam PF00419 Fimbrial protein 191 327 5.2E-11 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS06000 12a20191e3bb33640d029510863463e1 327 SUPERFAMILY SSF49401 195 327 6.96E-20 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06000 12a20191e3bb33640d029510863463e1 327 Gene3D G3DSA:2.60.40.1090 27 188 1.9E-13 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS08135 d85a8306fef6f8e84e261f595c50e92f 115 Gene3D G3DSA:1.20.58.80 15 113 4.2E-35 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS08135 d85a8306fef6f8e84e261f595c50e92f 115 PIRSF PIRSF000699 10 115 1.6E-40 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS08135 d85a8306fef6f8e84e261f595c50e92f 115 SUPERFAMILY SSF46973 14 113 2.62E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS08135 d85a8306fef6f8e84e261f595c50e92f 115 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 19 112 2.2E-32 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 SUPERFAMILY SSF117457 361 534 2.62E-56 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 Gene3D G3DSA:3.20.130.10 358 535 5.8E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 Pfam PF05683 Fumarase C-terminus 331 536 2.3E-82 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 78 324 1.7E-29 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 Pfam PF05681 Fumarate hydratase (Fumerase) 50 325 9.2E-80 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 372 535 1.9E-54 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 WM46_RS10905 fe15ad4a0528841bc2cb3f2800312cc2 550 PIRSF PIRSF001394 29 550 5.1E-218 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 WM46_RS20205 09bfb9ea6e2d8edb3060eee580a869a8 232 Pfam PF06176 Lipopolysaccharide core biosynthesis protein (WaaY) 1 229 3.6E-122 T 28-03-2018 IPR009330 Lipopolysaccharide core heptose(II) kinase WM46_RS20205 09bfb9ea6e2d8edb3060eee580a869a8 232 Gene3D G3DSA:1.10.510.10 24 226 1.6E-4 T 28-03-2018 WM46_RS20205 09bfb9ea6e2d8edb3060eee580a869a8 232 SUPERFAMILY SSF56112 98 180 1.6E-10 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS20205 09bfb9ea6e2d8edb3060eee580a869a8 232 SUPERFAMILY SSF56112 23 71 1.6E-10 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS25085 08bf72e100891c0b22489d409236de89 452 SUPERFAMILY SSF103473 13 444 6.54E-82 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS25085 08bf72e100891c0b22489d409236de89 452 Gene3D G3DSA:1.20.1250.20 11 217 8.5E-37 T 28-03-2018 WM46_RS25085 08bf72e100891c0b22489d409236de89 452 Pfam PF07690 Major Facilitator Superfamily 25 318 2.7E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS25085 08bf72e100891c0b22489d409236de89 452 PIRSF PIRSF002808 3 449 9.6E-45 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS25085 08bf72e100891c0b22489d409236de89 452 Gene3D G3DSA:1.20.1250.20 238 445 1.1E-25 T 28-03-2018 WM46_RS25085 08bf72e100891c0b22489d409236de89 452 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 27 436 1.2E-162 T 28-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS25615 7ee53ef30df6000e1a040c6a672bf9bb 394 Gene3D G3DSA:1.20.1250.20 199 392 5.5E-15 T 28-03-2018 WM46_RS25615 7ee53ef30df6000e1a040c6a672bf9bb 394 Gene3D G3DSA:1.20.1250.20 3 197 2.4E-27 T 28-03-2018 WM46_RS25615 7ee53ef30df6000e1a040c6a672bf9bb 394 SUPERFAMILY SSF103473 8 388 1.19E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS25615 7ee53ef30df6000e1a040c6a672bf9bb 394 Pfam PF07690 Major Facilitator Superfamily 218 385 1.9E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS25615 7ee53ef30df6000e1a040c6a672bf9bb 394 Pfam PF07690 Major Facilitator Superfamily 18 196 4.8E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS25045 d9c6bdf62fbcd2f5d2a1b29e65a9479d 429 TIGRFAM TIGR00814 stp: serine transporter 18 418 1.4E-184 T 28-03-2018 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS20770 9451654394b9ea60748c84a9c78ab673 280 Gene3D G3DSA:3.40.50.150 1 280 1.7E-91 T 28-03-2018 WM46_RS20770 9451654394b9ea60748c84a9c78ab673 280 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 278 5.3E-116 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 WM46_RS20770 9451654394b9ea60748c84a9c78ab673 280 SUPERFAMILY SSF53335 9 279 1.57E-99 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS20770 9451654394b9ea60748c84a9c78ab673 280 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 266 41.877 T 28-03-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 WM46_RS23900 7b0cc26682c22590ea83f755b6581fa5 67 Pfam PF04328 Selenoprotein, putative 5 67 4.9E-28 T 28-03-2018 IPR007423 Selenoprotein, putative WM46_RS02505 facc82fe5abf5fcb08566820763a45a2 452 Pfam PF07690 Major Facilitator Superfamily 28 286 5.6E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS02505 facc82fe5abf5fcb08566820763a45a2 452 SUPERFAMILY SSF103473 7 431 1.31E-83 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS02505 facc82fe5abf5fcb08566820763a45a2 452 Gene3D G3DSA:1.20.1250.20 12 212 4.1E-40 T 28-03-2018 WM46_RS02505 facc82fe5abf5fcb08566820763a45a2 452 Gene3D G3DSA:1.20.1250.20 231 433 4.5E-31 T 28-03-2018 WM46_RS19865 fb43e550d6da71464b323929a7c49889 150 ProDom PD093913 YICN MEMBRANE INNER EXPORTED 1 145 6.0E-71 T 28-03-2018 IPR009587 Protein of unknown function DUF1198 WM46_RS19865 fb43e550d6da71464b323929a7c49889 150 Pfam PF06711 Protein of unknown function (DUF1198) 1 143 7.2E-67 T 28-03-2018 IPR009587 Protein of unknown function DUF1198 WM46_RS19865 fb43e550d6da71464b323929a7c49889 150 Gene3D G3DSA:3.40.50.1220 5 134 8.9E-4 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS11905 c651fa67f22a780120f3167755753f86 253 Gene3D G3DSA:1.20.1290.10 8 253 7.3E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS11905 c651fa67f22a780120f3167755753f86 253 Pfam PF02627 Carboxymuconolactone decarboxylase family 165 247 1.3E-9 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS11905 c651fa67f22a780120f3167755753f86 253 Pfam PF02627 Carboxymuconolactone decarboxylase family 44 106 1.2E-4 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS11905 c651fa67f22a780120f3167755753f86 253 SUPERFAMILY SSF69118 21 240 1.67E-40 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS07310 3c3e862f217f2c31378202ddc1b3dd17 109 SUPERFAMILY SSF103481 12 108 1.7E-17 T 28-03-2018 WM46_RS07310 3c3e862f217f2c31378202ddc1b3dd17 109 Pfam PF00893 Small Multidrug Resistance protein 6 99 9.5E-29 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 WM46_RS07310 3c3e862f217f2c31378202ddc1b3dd17 109 Hamap MF_01597 Spermidine export protein MdtI [mdtI]. 1 109 34.05 T 28-03-2018 IPR023737 Spermidine export protein MdtI GO:0005886|GO:0015606|GO:0015848 WM46_RS07120 4b01085eb0dde08a8c52a77631a972ed 423 Gene3D G3DSA:3.40.50.2300 26 158 6.1E-23 T 28-03-2018 WM46_RS07120 4b01085eb0dde08a8c52a77631a972ed 423 SUPERFAMILY SSF53822 30 408 9.42E-94 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS07120 4b01085eb0dde08a8c52a77631a972ed 423 Pfam PF13433 Periplasmic binding protein domain 31 406 4.9E-173 T 28-03-2018 WM46_RS07120 4b01085eb0dde08a8c52a77631a972ed 423 Gene3D G3DSA:3.40.50.2300 159 345 1.2E-28 T 28-03-2018 WM46_RS07120 4b01085eb0dde08a8c52a77631a972ed 423 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 31 404 6.9E-179 T 28-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like WM46_RS07965 6a343ba944e5456849c7d9aa8dff2a75 348 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 348 2.4E-173 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM46_RS07965 6a343ba944e5456849c7d9aa8dff2a75 348 Pfam PF00793 DAHP synthetase I family 43 337 2.5E-106 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS07965 6a343ba944e5456849c7d9aa8dff2a75 348 PIRSF PIRSF001361 1 348 4.0E-158 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM46_RS07965 6a343ba944e5456849c7d9aa8dff2a75 348 SUPERFAMILY SSF51569 7 347 2.72E-131 T 28-03-2018 WM46_RS07965 6a343ba944e5456849c7d9aa8dff2a75 348 Gene3D G3DSA:3.20.20.70 7 348 6.6E-121 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16425 5c7d4e88de6152e84d636b7da01de514 122 Pfam PF06476 Protein of unknown function (DUF1090) 18 116 3.9E-38 T 28-03-2018 IPR009468 Protein of unknown function DUF1090 WM46_RS01800 c9f7b4fb906e74e52064506746767977 184 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 17 157 3.5E-33 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS16880 e2c0d3fcfb33d54bc2deac780d5df751 98 Gene3D G3DSA:3.30.750.24 14 97 1.1E-7 T 28-03-2018 IPR002645 STAS domain WM46_RS16880 e2c0d3fcfb33d54bc2deac780d5df751 98 SUPERFAMILY SSF52091 7 91 4.12E-14 T 28-03-2018 IPR002645 STAS domain WM46_RS16880 e2c0d3fcfb33d54bc2deac780d5df751 98 Pfam PF13466 STAS domain 14 90 5.8E-17 T 28-03-2018 IPR002645 STAS domain WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 Gene3D G3DSA:1.10.10.10 1 48 9.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 Gene3D G3DSA:1.10.10.10 131 233 0.25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 SUPERFAMILY SSF53098 235 382 1.77E-29 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 Pfam PF00665 Integrase core domain 236 339 1.4E-15 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 Gene3D G3DSA:1.10.10.60 61 104 7.4E-11 T 28-03-2018 WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 Pfam PF13936 Helix-turn-helix domain 61 102 2.3E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain WM46_RS13400 e0d1a2406860a39053c520937aa02e6e 386 Gene3D G3DSA:3.30.420.10 234 385 1.1E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 9.1E-44 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 231 1.3E-78 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 94 126 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 SUPERFAMILY SSF53790 1 235 1.7E-42 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 Gene3D G3DSA:3.40.1010.10 2 147 6.4E-24 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS03600 38c5f1af3f07388d160f0af10ab256d8 237 PIRSF PIRSF036427 1 236 3.8E-73 T 28-03-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 WM46_RS24725 1a094f8548ca9b64986c8c368c72b1b5 90 Pfam PF02583 Metal-sensitive transcriptional repressor 7 85 2.9E-20 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 WM46_RS23495 c87056c6860d08943bfe02c52cc6054e 249 SUPERFAMILY SSF53474 11 233 2.56E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23495 c87056c6860d08943bfe02c52cc6054e 249 Pfam PF00326 Prolyl oligopeptidase family 95 235 3.6E-10 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 WM46_RS23495 c87056c6860d08943bfe02c52cc6054e 249 Gene3D G3DSA:3.40.50.1820 2 249 1.9E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 Gene3D G3DSA:1.10.287.950 162 360 7.0E-46 T 28-03-2018 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 Gene3D G3DSA:1.10.287.950 57 161 1.6E-11 T 28-03-2018 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 2.7E-45 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 207 234 2.7E-45 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 31 51 2.7E-45 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 236 265 2.7E-45 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 130 159 2.7E-45 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 SUPERFAMILY SSF58104 76 357 1.57E-61 T 28-03-2018 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 SMART SM00283 109 356 2.7E-72 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS06220 5280a6e43cfe9e2a9ed29e614690d56d 377 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 168 324 1.1E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 WM46_RS24520 bca476b3c65ec78cad3549fde62c7f54 172 Gene3D G3DSA:2.60.40.1090 24 172 2.6E-35 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24520 bca476b3c65ec78cad3549fde62c7f54 172 SUPERFAMILY SSF49401 26 172 6.96E-32 T 28-03-2018 IPR008966 Adhesion domain WM46_RS24520 bca476b3c65ec78cad3549fde62c7f54 172 Pfam PF00419 Fimbrial protein 26 172 1.0E-14 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS18595 be0e4042b943f7ed85b9389fc2857cf8 334 Gene3D G3DSA:1.10.3470.10 64 333 1.7E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS18595 be0e4042b943f7ed85b9389fc2857cf8 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 62 318 8.6E-46 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 Pfam PF06725 3D domain 277 354 1.1E-24 T 28-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 SMART SM00925 125 257 7.7E-70 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 Gene3D G3DSA:2.40.240.50 58 259 1.4E-62 T 28-03-2018 WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 Pfam PF03562 MltA specific insert domain 95 257 1.8E-40 T 28-03-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 PIRSF PIRSF019422 145 365 1.2E-73 T 28-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 PIRSF PIRSF019422 1 147 6.5E-21 T 28-03-2018 IPR026044 Membrane-bound lytic murein transglycosylase A WM46_RS24950 81bfdbbf97e7874c6edbd7b71cd38ee4 365 SUPERFAMILY SSF50685 25 353 7.32E-115 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain WM46_RS16685 3f42d9a1b59f0f5c7574a13d6420ebe2 211 Pfam PF13460 NAD(P)H-binding 8 189 8.9E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS16685 3f42d9a1b59f0f5c7574a13d6420ebe2 211 Gene3D G3DSA:3.40.50.720 2 210 1.3E-20 T 28-03-2018 WM46_RS16685 3f42d9a1b59f0f5c7574a13d6420ebe2 211 SMART SM00859 3 103 0.0035 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 WM46_RS16685 3f42d9a1b59f0f5c7574a13d6420ebe2 211 SUPERFAMILY SSF51735 2 200 3.26E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS19065 81fa0e5ec3bdfd1f5a2886361cd4ca2b 206 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 18 202 3.3E-70 T 28-03-2018 IPR004778 Homoserine/Threonine efflux protein GO:0016021 WM46_RS19065 81fa0e5ec3bdfd1f5a2886361cd4ca2b 206 Pfam PF01810 LysE type translocator 14 205 8.4E-58 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS19065 81fa0e5ec3bdfd1f5a2886361cd4ca2b 206 PIRSF PIRSF006324 1 206 8.8E-43 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS12475 ced463d03e316d1b8e8eaf68fe5fdc7d 117 Pfam PF07237 Protein of unknown function (DUF1428) 2 103 3.9E-47 T 28-03-2018 IPR009874 Protein of unknown function DUF1428 WM46_RS12475 ced463d03e316d1b8e8eaf68fe5fdc7d 117 PIRSF PIRSF007028 1 117 6.7E-56 T 28-03-2018 IPR009874 Protein of unknown function DUF1428 WM46_RS12475 ced463d03e316d1b8e8eaf68fe5fdc7d 117 SUPERFAMILY SSF54909 1 116 3.22E-53 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS12475 ced463d03e316d1b8e8eaf68fe5fdc7d 117 Gene3D G3DSA:3.30.70.100 1 117 4.8E-61 T 28-03-2018 WM46_RS16980 27ef44d65f60cbb51d8bd489fc720be3 309 Pfam PF16199 Radical_SAM C-terminal domain 208 283 1.1E-17 T 28-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 WM46_RS16980 27ef44d65f60cbb51d8bd489fc720be3 309 SMART SM00729 23 247 1.5E-41 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 WM46_RS16980 27ef44d65f60cbb51d8bd489fc720be3 309 Pfam PF04055 Radical SAM superfamily 43 201 1.9E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS16980 27ef44d65f60cbb51d8bd489fc720be3 309 SUPERFAMILY SSF102114 13 262 1.44E-45 T 28-03-2018 WM46_RS16980 27ef44d65f60cbb51d8bd489fc720be3 309 Gene3D G3DSA:3.20.20.70 3 292 7.2E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16980 27ef44d65f60cbb51d8bd489fc720be3 309 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 301 2.2E-140 T 28-03-2018 IPR005911 Protein YhcC-like GO:0051536 WM46_RS04255 1ffad7e9a65af34c55d0fc2828562baf 322 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 7 320 1.0E-145 T 28-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 WM46_RS04255 1ffad7e9a65af34c55d0fc2828562baf 322 SUPERFAMILY SSF53335 90 322 8.44E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS04255 1ffad7e9a65af34c55d0fc2828562baf 322 Hamap MF_01590 tRNA U34 carboxymethyltransferase [cmoB]. 12 321 54.375 T 28-03-2018 IPR010017 tRNA U34 carboxymethyltransferase GO:0002098|GO:0016765 WM46_RS04255 1ffad7e9a65af34c55d0fc2828562baf 322 Pfam PF08003 Protein of unknown function (DUF1698) 7 321 4.1E-171 T 28-03-2018 IPR027555 tRNA (mo5U34)-methyltransferase-like WM46_RS04255 1ffad7e9a65af34c55d0fc2828562baf 322 Gene3D G3DSA:3.40.50.150 74 322 5.0E-24 T 28-03-2018 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 Pfam PF00376 MerR family regulatory protein 13 49 2.1E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 SMART SM00422 12 80 1.2E-22 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 24 8.9E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 24 37 8.9E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 8.9E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 Pfam PF09278 MerR, DNA binding 54 119 2.7E-15 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 SUPERFAMILY SSF46955 12 134 1.14E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 Gene3D G3DSA:1.10.1660.10 8 66 1.4E-18 T 28-03-2018 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 12 152 7.5E-75 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 WM46_RS21700 a5b5361199459e24ff2c1ab68d4ffcd3 154 Gene3D G3DSA:1.10.1660.10 67 142 1.1E-10 T 28-03-2018 WM46_RS08735 81ff20f8ce2e84831c31122dba4d2acc 397 Pfam PF07690 Major Facilitator Superfamily 12 315 4.8E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS08735 81ff20f8ce2e84831c31122dba4d2acc 397 Gene3D G3DSA:1.20.1250.20 1 188 6.4E-17 T 28-03-2018 WM46_RS08735 81ff20f8ce2e84831c31122dba4d2acc 397 SUPERFAMILY SSF103473 5 388 9.68E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS08735 81ff20f8ce2e84831c31122dba4d2acc 397 Gene3D G3DSA:1.20.1250.20 194 392 2.0E-20 T 28-03-2018 WM46_RS06940 b15d45adf4947f3807ca2bf770e42c4b 95 Pfam PF10734 Protein of unknown function (DUF2523) 9 88 1.2E-18 T 28-03-2018 IPR019670 Protein of unkown function DUF2523 WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 470 1.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 Gene3D G3DSA:3.30.565.10 336 486 1.7E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 Pfam PF08918 PhoQ Sensor 10 188 2.1E-85 T 28-03-2018 IPR015014 PhoQ Sensor GO:0000160|GO:0004673|GO:0005524|GO:0016020|GO:0018106|GO:0046872 WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 SUPERFAMILY SSF47384 250 320 5.49E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 5.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 5.3E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 SMART SM00387 375 481 2.4E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS08500 4ccd4758f5d26467192c5a04bb87bb9d 487 SUPERFAMILY SSF55874 337 477 2.23E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS14110 5b695e510470b9a98b7b35003d6f24e0 263 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 1.5E-103 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM46_RS14110 5b695e510470b9a98b7b35003d6f24e0 263 SUPERFAMILY SSF51621 4 262 3.51E-103 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 WM46_RS14110 5b695e510470b9a98b7b35003d6f24e0 263 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 263 4.4E-125 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM46_RS14110 5b695e510470b9a98b7b35003d6f24e0 263 Gene3D G3DSA:3.20.20.60 1 262 8.5E-83 T 28-03-2018 WM46_RS14110 5b695e510470b9a98b7b35003d6f24e0 263 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.783 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM46_RS14110 5b695e510470b9a98b7b35003d6f24e0 263 PIRSF PIRSF000388 1 263 1.0E-96 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 WM46_RS00785 2966a9af8d66b8ec3b0aa8f37a19dec0 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 44.247 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 WM46_RS00785 2966a9af8d66b8ec3b0aa8f37a19dec0 208 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 5.8E-65 T 28-03-2018 WM46_RS00785 2966a9af8d66b8ec3b0aa8f37a19dec0 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 4.0E-89 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 WM46_RS00785 2966a9af8d66b8ec3b0aa8f37a19dec0 208 Gene3D G3DSA:3.40.50.2020 1 206 1.3E-58 T 28-03-2018 WM46_RS00785 2966a9af8d66b8ec3b0aa8f37a19dec0 208 SUPERFAMILY SSF53271 4 206 5.77E-65 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS14890 a9e9c5bf403c9d8f1fc6d49fedef4489 211 Pfam PF01810 LysE type translocator 14 201 8.6E-56 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS14890 a9e9c5bf403c9d8f1fc6d49fedef4489 211 TIGRFAM TIGR00948 2a75: L-lysine exporter 15 191 8.5E-72 T 28-03-2018 IPR004777 L-lysine exporter/arginine exporter GO:0016021 WM46_RS14890 a9e9c5bf403c9d8f1fc6d49fedef4489 211 Hamap MF_01901 Arginine exporter protein ArgO [argO]. 1 205 39.567 T 28-03-2018 IPR023445 Arginine exporter protein ArgO, enterobacteria GO:0015181|GO:0015809 WM46_RS25070 3d7fc8c59ee6c30f6212a74a97190607 264 Gene3D G3DSA:3.30.2350.10 1 237 2.5E-60 T 28-03-2018 WM46_RS25070 3d7fc8c59ee6c30f6212a74a97190607 264 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25070 3d7fc8c59ee6c30f6212a74a97190607 264 Pfam PF00849 RNA pseudouridylate synthase 11 170 6.0E-29 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS25070 3d7fc8c59ee6c30f6212a74a97190607 264 SUPERFAMILY SSF55120 2 239 1.33E-61 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 Gene3D G3DSA:3.40.50.1220 185 311 1.6E-45 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 SMART SM00893 7 180 4.7E-13 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 SUPERFAMILY SSF52402 6 181 9.07E-27 T 28-03-2018 WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 Gene3D G3DSA:3.40.50.620 2 178 8.8E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 Pfam PF01012 Electron transfer flavoprotein domain 19 166 1.9E-17 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 SUPERFAMILY SSF52467 189 310 2.87E-41 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 PIRSF PIRSF000089 3 311 1.7E-79 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 WM46_RS07935 260654078ad179bfd4f88698cab74f16 311 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 189 271 6.5E-28 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 WM46_RS01980 aac3a5334c859ba946f3235d65f0744d 358 SUPERFAMILY SSF51695 32 352 1.2E-95 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 WM46_RS01980 aac3a5334c859ba946f3235d65f0744d 358 Gene3D G3DSA:3.20.20.190 29 356 1.3E-64 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 WM46_RS01980 aac3a5334c859ba946f3235d65f0744d 358 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 36 350 6.5E-75 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 WM46_RS20840 cb00a9397fe507bd2d8250416f525102 254 TIGRFAM TIGR02770 nickel_nikD: nickel import ATP-binding protein NikD 18 245 3.2E-104 T 28-03-2018 IPR014138 Nickel import ATP-binding protein NikD GO:0005886|GO:0015413|GO:0015675|GO:0016151 WM46_RS20840 cb00a9397fe507bd2d8250416f525102 254 SMART SM00382 28 218 3.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS20840 cb00a9397fe507bd2d8250416f525102 254 Gene3D G3DSA:3.40.50.300 1 246 1.7E-51 T 28-03-2018 WM46_RS20840 cb00a9397fe507bd2d8250416f525102 254 SUPERFAMILY SSF52540 5 241 7.34E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20840 cb00a9397fe507bd2d8250416f525102 254 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS20840 cb00a9397fe507bd2d8250416f525102 254 Pfam PF00005 ABC transporter 20 168 8.7E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS25270 88faeaab5b53f5ab38912facdfa09fe6 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.928 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 WM46_RS25270 88faeaab5b53f5ab38912facdfa09fe6 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 WM46_RS25270 88faeaab5b53f5ab38912facdfa09fe6 159 Gene3D G3DSA:3.30.1330.50 1 158 2.0E-73 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 WM46_RS25270 88faeaab5b53f5ab38912facdfa09fe6 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 156 4.0E-72 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 WM46_RS25270 88faeaab5b53f5ab38912facdfa09fe6 159 Pfam PF02542 YgbB family 1 154 1.0E-66 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 WM46_RS25270 88faeaab5b53f5ab38912facdfa09fe6 159 SUPERFAMILY SSF69765 1 156 1.44E-66 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 WM46_RS03790 8da148d4c2292f6fe35eaa80155e85b8 125 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 26 94 1.3E-23 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 WM46_RS03790 8da148d4c2292f6fe35eaa80155e85b8 125 Pfam PF04347 Flagellar biosynthesis protein, FliO 38 120 4.8E-21 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 441 8.1E-161 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 Pfam PF01235 Sodium:alanine symporter family 53 453 7.9E-146 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 PRINTS PR00175 Sodium/alanine symporter signature 206 225 2.1E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 PRINTS PR00175 Sodium/alanine symporter signature 303 321 2.1E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 PRINTS PR00175 Sodium/alanine symporter signature 87 109 2.1E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 PRINTS PR00175 Sodium/alanine symporter signature 349 371 2.1E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 PRINTS PR00175 Sodium/alanine symporter signature 178 196 2.1E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 PRINTS PR00175 Sodium/alanine symporter signature 410 430 2.1E-51 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS14790 d6c50dc0f986241aae169d7e979a9f3a 476 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 Pfam PF03925 SeqA protein C-terminal domain 71 179 1.2E-50 T 28-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 Gene3D G3DSA:1.10.1220.10 1 37 3.8E-25 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 SUPERFAMILY SSF82808 66 181 7.98E-50 T 28-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 Gene3D G3DSA:1.20.1380.10 75 177 1.1E-44 T 28-03-2018 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 Pfam PF17206 SeqA protein N-terminal domain 1 35 1.7E-23 T 28-03-2018 IPR033761 Negative modulator of initiation of replication SeqA, N-terminal WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 Hamap MF_00908 Negative modulator of initiation of replication [seqA]. 1 181 45.849 T 28-03-2018 IPR005621 Negative modulator of initiation of replication SeqA GO:0003677|GO:0032297 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 SUPERFAMILY SSF47598 1 35 4.78E-14 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM46_RS11150 94b1eb102675bf4d738faf0e2815afa6 181 PIRSF PIRSF019401 1 181 1.5E-52 T 28-03-2018 IPR005621 Negative modulator of initiation of replication SeqA GO:0003677|GO:0032297 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Gene3D G3DSA:3.30.65.10 99 143 2.4E-12 T 28-03-2018 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Gene3D G3DSA:3.30.65.10 58 98 2.8E-17 T 28-03-2018 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Gene3D G3DSA:3.30.65.10 8 57 6.8E-18 T 28-03-2018 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 SUPERFAMILY SSF57783 61 99 1.16E-13 T 28-03-2018 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 SUPERFAMILY SSF57783 12 49 6.12E-14 T 28-03-2018 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 145 167 0.13 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 13 49 1.1E-16 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 62 98 4.6E-18 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 104 142 5.6E-16 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 WM46_RS17360 e264e4f3ea1af738fe9e814898840252 184 Gene3D G3DSA:2.20.28.20 144 182 0.21 T 28-03-2018 WM46_RS10815 0045d8d18de345ae7db8e179a397a12b 142 Gene3D G3DSA:3.20.20.70 5 140 6.0E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS10815 0045d8d18de345ae7db8e179a397a12b 142 TIGRFAM TIGR02801 tolR: protein TolR 13 140 6.1E-39 T 28-03-2018 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 WM46_RS10815 0045d8d18de345ae7db8e179a397a12b 142 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 141 4.1E-24 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 WM46_RS05130 cf2de6a3845ede16fee6b09801f6427c 235 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 235 29.11 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 WM46_RS05130 cf2de6a3845ede16fee6b09801f6427c 235 SUPERFAMILY SSF63848 129 234 1.57E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 WM46_RS05130 cf2de6a3845ede16fee6b09801f6427c 235 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 132 231 5.9E-30 T 28-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 WM46_RS05130 cf2de6a3845ede16fee6b09801f6427c 235 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 6 234 1.4E-69 T 28-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 WM46_RS05130 cf2de6a3845ede16fee6b09801f6427c 235 Gene3D G3DSA:2.160.20.70 115 235 4.6E-30 T 28-03-2018 WM46_RS05130 cf2de6a3845ede16fee6b09801f6427c 235 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 103 9.6E-37 T 28-03-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 WM46_RS10870 5c2202686adb4784f2eb5d8baa620097 462 Gene3D G3DSA:3.30.420.40 1 272 9.8E-5 T 28-03-2018 WM46_RS10870 5c2202686adb4784f2eb5d8baa620097 462 PIRSF PIRSF004729 1 462 5.0E-200 T 28-03-2018 IPR006230 Protein MutL WM46_RS10870 5c2202686adb4784f2eb5d8baa620097 462 TIGRFAM TIGR01319 glmL_fam: conserved hypothetical protein 6 461 1.7E-241 T 28-03-2018 IPR006230 Protein MutL WM46_RS10870 5c2202686adb4784f2eb5d8baa620097 462 Pfam PF13941 MutL protein 4 455 3.7E-131 T 28-03-2018 IPR006230 Protein MutL WM46_RS09860 b062d85f12716748629f5846875e62fc 253 Gene3D G3DSA:3.30.2010.10 63 150 4.7E-18 T 28-03-2018 WM46_RS09860 b062d85f12716748629f5846875e62fc 253 Pfam PF01435 Peptidase family M48 77 247 2.8E-27 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM46_RS12710 9bb7304a4ae85cc9e6621b9cd55c6eca 262 Gene3D G3DSA:1.20.1630.10 2 258 2.9E-36 T 28-03-2018 WM46_RS12710 9bb7304a4ae85cc9e6621b9cd55c6eca 262 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 3 165 8.0E-24 T 28-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 WM46_RS18885 524b43dc28d258b0016e5d993f3782f7 311 SMART SM00563 97 224 7.4E-16 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS18885 524b43dc28d258b0016e5d993f3782f7 311 Pfam PF01553 Acyltransferase 84 221 3.5E-13 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 WM46_RS18885 524b43dc28d258b0016e5d993f3782f7 311 Gene3D G3DSA:3.40.1130.10 60 230 9.1E-21 T 28-03-2018 WM46_RS18885 524b43dc28d258b0016e5d993f3782f7 311 SUPERFAMILY SSF69593 28 296 4.18E-27 T 28-03-2018 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 Pfam PF02120 Flagellar hook-length control protein FliK 276 355 5.3E-21 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 264 286 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 126 149 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 386 402 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 2 15 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 307 322 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 21 38 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 289 307 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 241 263 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 322 345 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS03810 0d3fb5d7625c8dbd7e21471ad7a0526e 403 PRINTS PR01007 Flagellar hook-length control protein signature 65 81 3.9E-98 T 28-03-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 WM46_RS12285 5099c286cd238b375d96fbb6cb4b28eb 223 Pfam PF00005 ABC transporter 23 166 3.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS12285 5099c286cd238b375d96fbb6cb4b28eb 223 SUPERFAMILY SSF52540 5 213 9.91E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS12285 5099c286cd238b375d96fbb6cb4b28eb 223 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS12285 5099c286cd238b375d96fbb6cb4b28eb 223 Gene3D G3DSA:3.40.50.300 5 222 9.7E-57 T 28-03-2018 WM46_RS12285 5099c286cd238b375d96fbb6cb4b28eb 223 SMART SM00382 32 215 4.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 300 4.2E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 312 1.1E-136 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 Gene3D G3DSA:3.40.50.1100 134 323 3.2E-59 T 28-03-2018 WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 Gene3D G3DSA:3.40.50.1100 20 133 9.7E-33 T 28-03-2018 WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 312 1.8E-145 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 SUPERFAMILY SSF53686 3 317 2.23E-97 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme WM46_RS01140 f5e1f1f24efb1ce5271e5c88c2d89a0d 323 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 SUPERFAMILY SSF53850 96 294 1.66E-30 T 28-03-2018 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 8.0E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 SUPERFAMILY SSF46785 5 83 3.54E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 Gene3D G3DSA:1.10.10.10 7 88 3.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.3E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 Gene3D G3DSA:3.40.190.10 96 178 3.1E-9 T 28-03-2018 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 Gene3D G3DSA:3.40.190.10 179 266 3.4E-16 T 28-03-2018 WM46_RS10915 80d672b83c91140e64bb8ad81c1d478e 302 Pfam PF03466 LysR substrate binding domain 96 293 1.6E-28 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS09135 efc63a11c80afa0460ca8466a3f893c5 131 ProDom PD498860 RC0070 95 127 0.008 T 28-03-2018 WM46_RS09135 efc63a11c80afa0460ca8466a3f893c5 131 Pfam PF07007 Lysozyme inhibitor LprI 22 110 4.2E-19 T 28-03-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal WM46_RS13510 a8058ef33d49bda388e0c9047dd29cec 148 Pfam PF00583 Acetyltransferase (GNAT) family 39 136 1.9E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS13510 a8058ef33d49bda388e0c9047dd29cec 148 SUPERFAMILY SSF55729 1 143 1.66E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS13510 a8058ef33d49bda388e0c9047dd29cec 148 Gene3D G3DSA:3.40.630.30 1 146 2.3E-18 T 28-03-2018 WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 Gene3D G3DSA:1.10.150.310 83 126 4.8E-14 T 28-03-2018 WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 SUPERFAMILY SSF47781 47 123 7.23E-25 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 58 126 9.7E-37 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 SMART SM00278 74 93 80.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 SMART SM00278 104 123 13.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 Gene3D G3DSA:1.10.150.20 27 82 2.0E-8 T 28-03-2018 WM46_RS12605 f8e33adcead16cd8e9d64ec93cde658c 126 Pfam PF12836 Helix-hairpin-helix motif 63 122 5.2E-20 T 28-03-2018 WM46_RS11875 07ce137bab439f19895a32c583f4aa3a 349 SUPERFAMILY SSF53474 45 185 4.09E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11875 07ce137bab439f19895a32c583f4aa3a 349 SUPERFAMILY SSF53474 237 348 4.09E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11875 07ce137bab439f19895a32c583f4aa3a 349 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 57 255 7.9E-9 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 WM46_RS11875 07ce137bab439f19895a32c583f4aa3a 349 Gene3D G3DSA:3.40.50.1820 37 349 3.4E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS17140 a3ccecf3abba65cf4257ab3c79633efa 481 Gene3D G3DSA:3.30.2290.10 17 240 8.3E-56 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain WM46_RS17140 a3ccecf3abba65cf4257ab3c79633efa 481 Pfam PF01523 Putative modulator of DNA gyrase 35 332 1.5E-67 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 WM46_RS17140 a3ccecf3abba65cf4257ab3c79633efa 481 SUPERFAMILY SSF111283 22 480 1.7E-132 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 WM46_RS17140 a3ccecf3abba65cf4257ab3c79633efa 481 PIRSF PIRSF004919 14 481 2.9E-154 T 28-03-2018 IPR025502 TldD WM46_RS06510 9a05bfabf6e934d6cfa7dbed8621ed92 388 TIGRFAM TIGR00843 benE: benzoate transporter 1 382 4.4E-176 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 WM46_RS06510 9a05bfabf6e934d6cfa7dbed8621ed92 388 Pfam PF03594 Benzoate membrane transport protein 7 381 3.7E-146 T 28-03-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 WM46_RS09205 4f798a4863bc76b048c4250f2f62f8c3 175 PIRSF PIRSF017018 1 175 3.0E-73 T 28-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type WM46_RS09205 4f798a4863bc76b048c4250f2f62f8c3 175 Pfam PF10634 Fe2+ transport protein 25 173 6.9E-69 T 28-03-2018 IPR018470 Periplasmic metal-binding protein Tp34-type WM46_RS08205 5c36fbfff5009947960d93e9667e621b 224 Pfam PF09335 SNARE associated Golgi protein 67 184 4.1E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS10510 c5cd8a41a8698c47861bc935fd3d2358 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 290 309 2.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS10510 c5cd8a41a8698c47861bc935fd3d2358 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 253 277 2.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS10510 c5cd8a41a8698c47861bc935fd3d2358 368 PRINTS PR00164 ABC-2 type transport system membrane protein signature 310 329 2.3E-6 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS10510 c5cd8a41a8698c47861bc935fd3d2358 368 Pfam PF12698 ABC-2 family transporter protein 25 359 4.7E-47 T 28-03-2018 WM46_RS10510 c5cd8a41a8698c47861bc935fd3d2358 368 Gene3D G3DSA:3.40.1710.10 38 188 3.5E-25 T 28-03-2018 WM46_RS00805 5a7aca4c39d5182ce321394df2b3ed42 319 SUPERFAMILY SSF56235 2 284 4.12E-76 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS00805 5a7aca4c39d5182ce321394df2b3ed42 319 Gene3D G3DSA:3.60.20.30 150 285 1.7E-36 T 28-03-2018 WM46_RS00805 5a7aca4c39d5182ce321394df2b3ed42 319 Pfam PF01112 Asparaginase 15 279 2.9E-64 T 28-03-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 Pfam PF07559 Flagellar basal body protein FlaE 172 307 6.7E-20 T 28-03-2018 IPR011491 Flagellar hook protein FlgE WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 Pfam PF00460 Flagella basal body rod protein 4 33 1.2E-11 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 348 425 3.3E-20 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 Gene3D G3DSA:2.60.98.20 146 308 2.9E-29 T 28-03-2018 IPR011491 Flagellar hook protein FlgE WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 SUPERFAMILY SSF117143 73 387 3.53E-81 T 28-03-2018 WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site WM46_RS08775 5ee6f5ef9284da8425863e1a6d0aec46 426 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 408 1.2E-96 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G WM46_RS24955 9a151c032a8f8b5b3a75ad287d24b71b 268 SUPERFAMILY SSF69572 10 259 2.88E-62 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 WM46_RS24955 9a151c032a8f8b5b3a75ad287d24b71b 268 Pfam PF00899 ThiF family 20 260 1.2E-35 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 WM46_RS24955 9a151c032a8f8b5b3a75ad287d24b71b 268 Gene3D G3DSA:3.40.50.720 3 267 2.3E-52 T 28-03-2018 WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 Gene3D G3DSA:1.20.1250.20 255 503 2.7E-32 T 28-03-2018 WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 498 1.9E-217 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 Gene3D G3DSA:1.20.1250.20 14 203 9.0E-32 T 28-03-2018 WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 Pfam PF07690 Major Facilitator Superfamily 19 413 1.7E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 SUPERFAMILY SSF103473 475 500 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 SUPERFAMILY SSF103473 9 196 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS25590 48fe13367e62af4e0e336aff95e75744 512 SUPERFAMILY SSF103473 251 423 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS03490 9d242cdc179d017d5116f2390e3a1655 91 SMART SM00877 3 79 2.6E-38 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03490 9d242cdc179d017d5116f2390e3a1655 91 Pfam PF00936 BMC domain 4 79 6.1E-30 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS03490 9d242cdc179d017d5116f2390e3a1655 91 SUPERFAMILY SSF143414 3 89 3.27E-32 T 28-03-2018 WM46_RS03490 9d242cdc179d017d5116f2390e3a1655 91 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 21 40 - T 28-03-2018 IPR020808 Bacterial microcompartments protein, conserved site WM46_RS03490 9d242cdc179d017d5116f2390e3a1655 91 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 45 5.0E-16 T 28-03-2018 WM46_RS01835 c11f9452e7528f614a097813189a4d61 155 Pfam PF13673 Acetyltransferase (GNAT) domain 46 149 1.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS01835 c11f9452e7528f614a097813189a4d61 155 Gene3D G3DSA:3.40.630.30 1 154 9.3E-33 T 28-03-2018 WM46_RS01835 c11f9452e7528f614a097813189a4d61 155 SUPERFAMILY SSF55729 1 150 2.93E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 Gene3D G3DSA:3.50.50.60 1 426 5.1E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 410 54.75 T 28-03-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 Pfam PF01266 FAD dependent oxidoreductase 2 396 7.6E-74 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 SUPERFAMILY SSF51905 107 271 1.11E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 SUPERFAMILY SSF51905 1 54 1.11E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 SUPERFAMILY SSF51905 359 416 1.11E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS05175 b1aef60bc8f192ceb88cb587bea015d6 432 SUPERFAMILY SSF54373 269 359 1.11E-16 T 28-03-2018 WM46_RS03195 20e9af5e8770359eeee71f663cdd2de5 121 Pfam PF05866 Endodeoxyribonuclease RusA 6 114 1.5E-12 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 WM46_RS03195 20e9af5e8770359eeee71f663cdd2de5 121 Gene3D G3DSA:3.30.1330.70 3 119 4.6E-9 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 WM46_RS03195 20e9af5e8770359eeee71f663cdd2de5 121 SUPERFAMILY SSF103084 7 114 2.48E-10 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 Gene3D G3DSA:3.30.420.40 217 373 6.2E-29 T 28-03-2018 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 Gene3D G3DSA:3.30.420.40 3 182 2.3E-54 T 28-03-2018 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 5 367 3.1E-171 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 SUPERFAMILY SSF53067 66 111 2.89E-29 T 28-03-2018 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 SUPERFAMILY SSF53067 143 341 2.89E-29 T 28-03-2018 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 SUPERFAMILY SSF53067 5 36 2.89E-29 T 28-03-2018 WM46_RS07500 38f67b609b55bcf53aa0f34fa56c99e4 373 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 4 367 41.656 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 WM46_RS10920 f3112a9b35e50c3042c34a649dc61060 259 Gene3D G3DSA:3.40.1010.10 4 129 4.3E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS10920 f3112a9b35e50c3042c34a649dc61060 259 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 5 240 1.7E-94 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS10920 f3112a9b35e50c3042c34a649dc61060 259 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 216 3.7E-44 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS10920 f3112a9b35e50c3042c34a649dc61060 259 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 10 24 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 WM46_RS10920 f3112a9b35e50c3042c34a649dc61060 259 SUPERFAMILY SSF53790 4 246 3.53E-78 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS10920 f3112a9b35e50c3042c34a649dc61060 259 Gene3D G3DSA:3.30.950.10 130 257 9.4E-36 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 WM46_RS25135 2beb68d91999ce554f827af07dc5d07f 274 SUPERFAMILY SSF46689 6 81 4.3E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS25135 2beb68d91999ce554f827af07dc5d07f 274 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 79 1.5E-18 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS25135 2beb68d91999ce554f827af07dc5d07f 274 SUPERFAMILY SSF53697 89 255 4.32E-32 T 28-03-2018 WM46_RS25135 2beb68d91999ce554f827af07dc5d07f 274 Gene3D G3DSA:3.40.50.10490 88 271 2.9E-32 T 28-03-2018 WM46_RS25135 2beb68d91999ce554f827af07dc5d07f 274 Pfam PF01380 SIS domain 121 248 1.6E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS25135 2beb68d91999ce554f827af07dc5d07f 274 Gene3D G3DSA:1.10.10.10 1 81 6.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 Gene3D G3DSA:2.40.10.10 74 177 1.4E-4 T 28-03-2018 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 SUPERFAMILY SSF50494 120 264 1.84E-28 T 28-03-2018 IPR009003 Peptidase S1, PA clan WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 SUPERFAMILY SSF50494 32 84 1.84E-28 T 28-03-2018 IPR009003 Peptidase S1, PA clan WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 Pfam PF00089 Trypsin 48 243 1.2E-8 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 PRINTS PR00839 V8 serine protease family signature 211 227 2.0E-20 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 PRINTS PR00839 V8 serine protease family signature 231 243 2.0E-20 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 PRINTS PR00839 V8 serine protease family signature 43 60 2.0E-20 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 PRINTS PR00839 V8 serine protease family signature 177 190 2.0E-20 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 PRINTS PR00839 V8 serine protease family signature 68 85 2.0E-20 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 Gene3D G3DSA:2.40.10.10 178 270 9.4E-12 T 28-03-2018 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 Gene3D G3DSA:2.40.10.10 45 73 1.7E-6 T 28-03-2018 WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 216 227 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site WM46_RS07305 073371c64480b26629235bdd0c7f7da5 273 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 79 84 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 WM46_RS04765 9915af68647e03400f03a6acda43cacb 256 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 8 251 3.2E-43 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail WM46_RS04765 9915af68647e03400f03a6acda43cacb 256 Pfam PF05100 Phage minor tail protein L 24 251 4.1E-57 T 28-03-2018 IPR006487 Bacteriophage lambda, GpL, minor tail WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 Pfam PF03466 LysR substrate binding domain 93 291 7.2E-42 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 Gene3D G3DSA:3.40.190.10 178 264 1.1E-18 T 28-03-2018 WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 Gene3D G3DSA:3.40.190.10 91 177 9.6E-20 T 28-03-2018 WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 SUPERFAMILY SSF46785 4 85 2.11E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 SUPERFAMILY SSF53850 95 297 2.11E-41 T 28-03-2018 WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.6E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 Gene3D G3DSA:1.10.10.10 1 85 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS17930 a21ac4991bc637a8d9ababac3f62d3dc 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 SMART SM00354 1 73 7.4E-32 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 SUPERFAMILY SSF47413 2 58 9.57E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 62 312 1.3E-13 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 2 50 4.9E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 Gene3D G3DSA:3.40.50.2300 166 332 3.1E-19 T 28-03-2018 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 Gene3D G3DSA:3.40.50.2300 57 165 6.6E-26 T 28-03-2018 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 Gene3D G3DSA:1.10.260.40 1 56 7.6E-20 T 28-03-2018 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 28-03-2018 WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 SUPERFAMILY SSF53822 60 314 2.16E-41 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS14430 5cb0a92e732dc014f6601910fa8d666f 334 TIGRFAM TIGR02417 fruct_sucro_rep: D-fructose-responsive transcription factor 2 328 1.2E-154 T 28-03-2018 IPR012781 D-fructose-responsive transcription factor GO:0003677|GO:0006355|GO:0009750 WM46_RS09080 e2fe5ba1ba0abe81c17b4b5dc3536fb6 289 Gene3D G3DSA:1.10.530.10 44 200 1.4E-4 T 28-03-2018 WM46_RS18295 16294f433499604d4f670b810be37db4 772 Gene3D G3DSA:1.20.1640.10 595 707 1.1E-8 T 28-03-2018 WM46_RS18295 16294f433499604d4f670b810be37db4 772 Gene3D G3DSA:1.20.1640.10 714 765 0.13 T 28-03-2018 WM46_RS18295 16294f433499604d4f670b810be37db4 772 Gene3D G3DSA:1.20.1640.10 210 408 4.5E-22 T 28-03-2018 WM46_RS18295 16294f433499604d4f670b810be37db4 772 Pfam PF03176 MMPL family 250 401 6.5E-10 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 WM46_RS18295 16294f433499604d4f670b810be37db4 772 SUPERFAMILY SSF82866 226 403 1.7E-20 T 28-03-2018 WM46_RS18295 16294f433499604d4f670b810be37db4 772 SUPERFAMILY SSF82866 637 764 2.22E-16 T 28-03-2018 WM46_RS00150 deb809f473ac88dfe49383ddc1390b45 114 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 4 112 34.158 T 28-03-2018 IPR026592 Outer membrane protein assembly factor BamE WM46_RS00150 deb809f473ac88dfe49383ddc1390b45 114 Gene3D G3DSA:3.30.1450.10 35 109 9.8E-12 T 28-03-2018 WM46_RS00150 deb809f473ac88dfe49383ddc1390b45 114 Pfam PF04355 SmpA / OmlA family 35 104 7.2E-28 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 SUPERFAMILY SSF117143 93 222 1.24E-34 T 28-03-2018 WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 Pfam PF00460 Flagella basal body rod protein 5 35 8.8E-14 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 145 243 2.4E-29 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 8.2E-49 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 1.4E-117 T 28-03-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 260 1.2E-26 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain WM46_RS08765 d9ff8cd09877a3b782fcc8113c18ad73 260 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site WM46_RS13030 3f1df80cd4bf6130ab7a689dd515add3 177 Pfam PF00857 Isochorismatase family 7 137 6.6E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS13030 3f1df80cd4bf6130ab7a689dd515add3 177 SUPERFAMILY SSF52499 3 157 2.88E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS13030 3f1df80cd4bf6130ab7a689dd515add3 177 Gene3D G3DSA:3.40.50.850 1 176 2.2E-35 T 28-03-2018 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00156 Type I copper blue protein family signature 46 59 8.5E-9 T 28-03-2018 IPR001235 Blue (type 1) copper protein, plastocyanin-type GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00156 Type I copper blue protein family signature 60 75 8.5E-9 T 28-03-2018 IPR001235 Blue (type 1) copper protein, plastocyanin-type GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00156 Type I copper blue protein family signature 92 106 8.5E-9 T 28-03-2018 IPR001235 Blue (type 1) copper protein, plastocyanin-type GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 SUPERFAMILY SSF49503 24 140 4.0E-24 T 28-03-2018 IPR008972 Cupredoxin WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00155 Amicyanin family signature 81 96 3.1E-23 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00155 Amicyanin family signature 40 59 3.1E-23 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00155 Amicyanin family signature 60 75 3.1E-23 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00155 Amicyanin family signature 97 112 3.1E-23 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 PRINTS PR00155 Amicyanin family signature 24 39 3.1E-23 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 Gene3D G3DSA:2.60.40.420 23 145 3.1E-14 T 28-03-2018 IPR008972 Cupredoxin WM46_RS05500 2ac04db5ca886faf0acb45b36aa0a043 146 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 29 114 4.6E-12 T 28-03-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 WM46_RS23920 8e9f0f95e68cb6588716e0819d909136 171 SUPERFAMILY SSF55729 1 138 2.19E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS23920 8e9f0f95e68cb6588716e0819d909136 171 Gene3D G3DSA:3.40.630.30 1 171 1.6E-24 T 28-03-2018 WM46_RS23920 8e9f0f95e68cb6588716e0819d909136 171 Pfam PF00583 Acetyltransferase (GNAT) family 46 134 2.8E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS17440 1d39cb39316a9c2998ec292730c96ef2 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 5.9E-22 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17440 1d39cb39316a9c2998ec292730c96ef2 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17440 1d39cb39316a9c2998ec292730c96ef2 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 3.0E-10 T 28-03-2018 WM46_RS17440 1d39cb39316a9c2998ec292730c96ef2 38 Pfam PF00444 Ribosomal protein L36 1 38 2.3E-20 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17440 1d39cb39316a9c2998ec292730c96ef2 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 17.829 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17440 1d39cb39316a9c2998ec292730c96ef2 38 SUPERFAMILY SSF57840 1 38 5.89E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS21505 0b33df07dcb3480221afabd89bc87a45 80 ProDom PD865006 YJBE PRECURSOR SIGNAL MEMBRANE OUTER EXPORTED 1 28 1.0E-7 T 28-03-2018 WM46_RS21505 0b33df07dcb3480221afabd89bc87a45 80 Pfam PF11106 Exopolysaccharide production protein YjbE 1 79 1.0E-28 T 28-03-2018 IPR025858 Exopolysaccharide production protein YjbE WM46_RS23290 442fe58adb6062bc5662e11eeda02349 325 PIRSF PIRSF006470 1 325 3.6E-102 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 WM46_RS23290 442fe58adb6062bc5662e11eeda02349 325 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 310 7.8E-74 T 28-03-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 WM46_RS23290 442fe58adb6062bc5662e11eeda02349 325 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 288 1.7E-64 T 28-03-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 WM46_RS23290 442fe58adb6062bc5662e11eeda02349 325 Gene3D G3DSA:3.40.190.10 147 270 0.025 T 28-03-2018 WM46_RS04185 744d5222fb7511eb7df7547829184693 129 SMART SM00448 6 120 2.4E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS04185 744d5222fb7511eb7df7547829184693 129 Gene3D G3DSA:3.40.50.2300 3 128 3.5E-35 T 28-03-2018 WM46_RS04185 744d5222fb7511eb7df7547829184693 129 SUPERFAMILY SSF52172 5 125 6.26E-35 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS04185 744d5222fb7511eb7df7547829184693 129 Pfam PF00072 Response regulator receiver domain 9 120 8.2E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS00090 5cabb791718289cbc1e65ed7877acfd6 377 Pfam PF14350 Beta protein 5 359 4.1E-69 T 28-03-2018 IPR025683 Protein beta WM46_RS22430 f1ef4c30a3174e76210256644f8c6084 546 Pfam PF13954 PapC N-terminal domain 63 271 5.1E-26 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS22430 f1ef4c30a3174e76210256644f8c6084 546 SUPERFAMILY SSF141729 63 137 3.53E-11 T 28-03-2018 WM46_RS22430 f1ef4c30a3174e76210256644f8c6084 546 Pfam PF00577 Outer membrane usher protein 288 519 1.5E-59 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS22430 f1ef4c30a3174e76210256644f8c6084 546 SUPERFAMILY SSF141729 215 262 5.36E-9 T 28-03-2018 WM46_RS00075 6fbd3179d2c9ba86fdbf712be9b893cc 370 Pfam PF13394 4Fe-4S single cluster domain 98 193 2.3E-6 T 28-03-2018 WM46_RS00075 6fbd3179d2c9ba86fdbf712be9b893cc 370 SUPERFAMILY SSF102114 95 353 3.4E-24 T 28-03-2018 WM46_RS00075 6fbd3179d2c9ba86fdbf712be9b893cc 370 TIGRFAM TIGR03977 rSAM_pair_HxsC: His-Xaa-Ser system radical SAM maturase HxsC 68 358 3.5E-122 T 28-03-2018 IPR024032 His-Xaa-Ser system radical SAM maturase HxsC WM46_RS00075 6fbd3179d2c9ba86fdbf712be9b893cc 370 Pfam PF04055 Radical SAM superfamily 96 240 1.2E-7 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS00075 6fbd3179d2c9ba86fdbf712be9b893cc 370 Gene3D G3DSA:3.20.20.70 79 362 1.5E-17 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS15085 06727a09e054f179c06951850809e604 188 Pfam PF02325 YGGT family 10 78 4.5E-22 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 WM46_RS15085 06727a09e054f179c06951850809e604 188 Pfam PF02325 YGGT family 104 167 3.7E-16 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 WM46_RS24555 08f74e6690d43bfe03c9a04e47b9c009 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.2E-12 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain WM46_RS24555 08f74e6690d43bfe03c9a04e47b9c009 101 Gene3D G3DSA:3.30.70.100 1 94 1.4E-18 T 28-03-2018 WM46_RS24555 08f74e6690d43bfe03c9a04e47b9c009 101 SUPERFAMILY SSF54909 1 98 1.07E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS12685 3f1e2dbba01eae14fd618ff5e67566a5 296 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 4 282 1.4E-93 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 WM46_RS12685 3f1e2dbba01eae14fd618ff5e67566a5 296 Pfam PF01040 UbiA prenyltransferase family 19 265 1.6E-61 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 WM46_RS12685 3f1e2dbba01eae14fd618ff5e67566a5 296 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 2 284 18.132 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 WM46_RS12685 3f1e2dbba01eae14fd618ff5e67566a5 296 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 57 79 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site WM46_RS09310 c06071eed0a8d48e97ce78de36f1d777 263 Pfam PF02223 Thymidylate kinase 25 203 3.2E-5 T 28-03-2018 WM46_RS09310 c06071eed0a8d48e97ce78de36f1d777 263 Gene3D G3DSA:3.40.50.300 19 248 1.7E-16 T 28-03-2018 WM46_RS09310 c06071eed0a8d48e97ce78de36f1d777 263 SUPERFAMILY SSF52540 20 222 1.01E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13480 10767fda0873931aec7ee9067eda4511 747 Gene3D G3DSA:2.115.10.20 267 733 7.8E-18 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain WM46_RS13480 10767fda0873931aec7ee9067eda4511 747 Pfam PF04616 Glycosyl hydrolases family 43 275 470 5.2E-8 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 WM46_RS13480 10767fda0873931aec7ee9067eda4511 747 SUPERFAMILY SSF75005 276 528 2.14E-16 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain WM46_RS13480 10767fda0873931aec7ee9067eda4511 747 Pfam PF03906 Phage T7 tail fibre protein 8 153 9.1E-10 T 28-03-2018 IPR005604 Bacteriophage T7 tail fibre protein WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 SUPERFAMILY SSF46689 59 108 1.75E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 Gene3D G3DSA:1.10.10.60 60 112 1.2E-13 T 28-03-2018 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 Pfam PF12833 Helix-turn-helix domain 28 106 1.6E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 89 105 2.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 74 89 2.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 SMART SM00342 22 105 9.9E-35 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 Gene3D G3DSA:1.10.10.60 2 59 1.1E-14 T 28-03-2018 WM46_RS11750 42242121a5cce5ad891cca2294530d18 113 SUPERFAMILY SSF46689 6 56 3.14E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS19225 4a905a9ba98fe21d0c31f7e45eaa3bc2 293 SUPERFAMILY SSF53448 1 286 2.05E-91 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS19225 4a905a9ba98fe21d0c31f7e45eaa3bc2 293 Pfam PF00483 Nucleotidyl transferase 2 238 1.2E-71 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM46_RS19225 4a905a9ba98fe21d0c31f7e45eaa3bc2 293 Gene3D G3DSA:3.90.550.10 1 292 4.2E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS19225 4a905a9ba98fe21d0c31f7e45eaa3bc2 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.7E-160 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 WM46_RS04190 16158a9b5bc42173ea6d6d69bae8452e 214 SUPERFAMILY SSF75708 11 213 8.5E-68 T 28-03-2018 WM46_RS04190 16158a9b5bc42173ea6d6d69bae8452e 214 PIRSF PIRSF002884 2 214 9.8E-89 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 WM46_RS04190 16158a9b5bc42173ea6d6d69bae8452e 214 Gene3D G3DSA:1.10.287.500 36 168 1.7E-22 T 28-03-2018 WM46_RS04190 16158a9b5bc42173ea6d6d69bae8452e 214 Pfam PF04344 Chemotaxis phosphatase, CheZ 17 214 3.0E-77 T 28-03-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 WM46_RS04190 16158a9b5bc42173ea6d6d69bae8452e 214 Gene3D G3DSA:1.20.5.590 7 34 2.8E-16 T 28-03-2018 WM46_RS25860 b1c1e9fe53a531c83b7fd6cba9930447 196 Gene3D G3DSA:2.60.120.620 34 196 2.5E-4 T 28-03-2018 WM46_RS25860 b1c1e9fe53a531c83b7fd6cba9930447 196 Pfam PF13661 2OG-Fe(II) oxygenase superfamily 102 179 2.0E-8 T 28-03-2018 WM46_RS02580 639185101a285a3b8874ead92ef6986c 388 Gene3D G3DSA:1.10.3720.10 8 386 5.3E-24 T 28-03-2018 WM46_RS02580 639185101a285a3b8874ead92ef6986c 388 SUPERFAMILY SSF161098 176 374 3.4E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS02580 639185101a285a3b8874ead92ef6986c 388 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 198 376 5.5E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS05150 70fde87be5b876c3bfed4e5581a6fd11 113 SUPERFAMILY SSF51197 4 101 2.56E-32 T 28-03-2018 WM46_RS05150 70fde87be5b876c3bfed4e5581a6fd11 113 Pfam PF09313 Domain of unknown function (DUF1971) 14 94 1.5E-26 T 28-03-2018 IPR015392 Domain of unknown function DUF1971 WM46_RS05150 70fde87be5b876c3bfed4e5581a6fd11 113 Gene3D G3DSA:2.60.120.10 6 107 3.8E-41 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS05150 70fde87be5b876c3bfed4e5581a6fd11 113 PIRSF PIRSF020632 3 112 7.0E-63 T 28-03-2018 IPR014510 Tellurite resistance predicted, YeaR WM46_RS16335 b9b72c7380d18dc26b8e6cd2c49a21be 185 SUPERFAMILY SSF46785 41 158 8.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16335 b9b72c7380d18dc26b8e6cd2c49a21be 185 Gene3D G3DSA:1.10.10.10 29 158 9.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16335 b9b72c7380d18dc26b8e6cd2c49a21be 185 Pfam PF03551 Transcriptional regulator PadR-like family 45 114 2.5E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 348 1.4E-124 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 2.9E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 2.9E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 2.9E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 2.9E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 303 324 2.9E-42 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 355 1.0E-139 T 28-03-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 Gene3D G3DSA:3.40.1690.10 219 354 1.3E-58 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal WM46_RS04215 9725cba93b3fee2b68a775fbb57533a3 384 SUPERFAMILY SSF160544 245 352 1.22E-41 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal WM46_RS02160 9f8f334ac749d7811acd2beec104baee 200 Gene3D G3DSA:1.10.468.10 44 198 1.4E-29 T 28-03-2018 WM46_RS02160 9f8f334ac749d7811acd2beec104baee 200 PIRSF PIRSF000013 1 200 6.5E-107 T 28-03-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 WM46_RS02160 9f8f334ac749d7811acd2beec104baee 200 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 22 193 6.4E-78 T 28-03-2018 IPR005126 NapC/NirT cytochrome c, N-terminal WM46_RS02160 9f8f334ac749d7811acd2beec104baee 200 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 11 194 4.9E-105 T 28-03-2018 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 WM46_RS02160 9f8f334ac749d7811acd2beec104baee 200 SUPERFAMILY SSF48695 17 196 7.64E-65 T 28-03-2018 IPR011031 Multihaem cytochrome WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 Gene3D G3DSA:1.10.10.200 1 78 5.9E-30 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 Gene3D G3DSA:3.30.70.980 178 247 4.5E-13 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 Pfam PF01709 Transcriptional regulator 5 235 8.0E-95 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 Gene3D G3DSA:3.30.70.980 83 177 1.8E-31 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 238 36.607 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 SUPERFAMILY SSF75625 3 244 3.79E-97 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS04290 bf853b0424f1eb298b6ef0d263e96738 247 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 236 1.3E-106 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS05945 1068e780d5d098716befc3590f452682 108 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 8 108 1.1E-38 T 28-03-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 WM46_RS05945 1068e780d5d098716befc3590f452682 108 SUPERFAMILY SSF55159 6 104 3.66E-25 T 28-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 WM46_RS05945 1068e780d5d098716befc3590f452682 108 Gene3D G3DSA:3.30.780.10 16 106 2.4E-20 T 28-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 WM46_RS05945 1068e780d5d098716befc3590f452682 108 PIRSF PIRSF037511 1 108 1.8E-35 T 28-03-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 WM46_RS05945 1068e780d5d098716befc3590f452682 108 Pfam PF01253 Translation initiation factor SUI1 32 101 1.6E-18 T 28-03-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 WM46_RS23625 f3016143ea4e5d96e413a3ddbb437a82 154 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 57 154 1.0E-41 T 28-03-2018 IPR004914 Antirestriction protein WM46_RS23625 f3016143ea4e5d96e413a3ddbb437a82 154 Pfam PF03230 Antirestriction protein 59 154 3.4E-34 T 28-03-2018 IPR004914 Antirestriction protein WM46_RS24295 6e7761cd1490dabe76df15efc9ea5adc 455 Pfam PF00860 Permease family 32 415 2.2E-79 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 304 9.7E-106 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 Pfam PF05175 Methyltransferase small domain 134 215 9.6E-16 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 13 295 1.9E-138 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 SUPERFAMILY SSF53335 15 294 3.85E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 Gene3D G3DSA:1.10.8.10 14 101 1.3E-12 T 28-03-2018 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 PIRSF PIRSF037167 2 307 2.4E-149 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 204 210 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 300 54.275 T 28-03-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 WM46_RS01500 8f137ee792f3f1cef7646effd2427c2c 310 Gene3D G3DSA:3.40.50.150 102 274 4.3E-35 T 28-03-2018 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 Pfam PF04223 Citrate lyase, alpha subunit (CitF) 43 508 1.2E-264 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 Gene3D G3DSA:3.40.1080.10 241 484 1.8E-36 T 28-03-2018 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 Gene3D G3DSA:3.40.1080.10 2 239 2.0E-46 T 28-03-2018 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 TIGRFAM TIGR01584 citF: citrate lyase, alpha subunit 35 510 1.0E-240 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 PIRSF PIRSF009451 1 510 9.8E-265 T 28-03-2018 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 SUPERFAMILY SSF100950 242 508 2.09E-59 T 28-03-2018 WM46_RS11490 7f4dbb894cb94fd4052f88c2dc23d843 510 SUPERFAMILY SSF100950 34 238 1.29E-72 T 28-03-2018 WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 SUPERFAMILY SSF51556 56 354 7.53E-54 T 28-03-2018 IPR032466 Metal-dependent hydrolase WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 TIGRFAM TIGR03314 Se_ssnA: putative selenium metabolism protein SsnA 2 438 1.1E-211 T 28-03-2018 IPR017700 Putative aminohydrolase SsnA WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 Pfam PF01979 Amidohydrolase family 53 410 3.0E-47 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 SUPERFAMILY SSF51338 1 56 9.13E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 SUPERFAMILY SSF51338 361 435 9.13E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 Gene3D G3DSA:2.30.40.10 349 437 8.1E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 Gene3D G3DSA:3.20.20.140 69 348 1.6E-26 T 28-03-2018 WM46_RS24320 ee81ef1bc064be702d5a9b0e1d4706f3 442 Gene3D G3DSA:2.30.40.10 1 68 1.7E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 SUPERFAMILY SSF52794 105 205 1.24E-34 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 Gene3D G3DSA:3.40.50.2300 35 84 0.024 T 28-03-2018 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 Gene3D G3DSA:3.40.50.2300 105 202 5.1E-37 T 28-03-2018 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 SUPERFAMILY SSF52794 4 88 2.96E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 107 190 1.7E-39 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 Pfam PF02378 Phosphotransferase system, EIIC 233 496 1.5E-17 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 108 192 1.3E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS02380 5d6d198ca4faaea2cc8079ce3523b932 563 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 215 552 4.0E-149 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 WM46_RS20555 4a230fc44244c33ac659104774a80382 143 SUPERFAMILY SSF55729 1 129 1.55E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS20555 4a230fc44244c33ac659104774a80382 143 Gene3D G3DSA:3.40.630.30 1 142 1.8E-19 T 28-03-2018 WM46_RS20555 4a230fc44244c33ac659104774a80382 143 Pfam PF13673 Acetyltransferase (GNAT) domain 45 125 2.7E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 3.0E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 Gene3D G3DSA:1.20.120.530 83 229 4.9E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 Pfam PF07729 FCD domain 96 219 2.6E-18 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 SUPERFAMILY SSF46785 2 76 5.32E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 SUPERFAMILY SSF48008 94 222 8.37E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 Gene3D G3DSA:1.10.10.10 1 74 3.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 SMART SM00895 96 220 8.2E-16 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS16410 77138890cca5c51b2e5906ea91b9ebf4 258 SMART SM00345 13 72 4.0E-25 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS15525 7db829023da510a0b58877ff3094a32e 115 TIGRFAM TIGR01690 ICE_RAQPRD: integrative conjugative element protein, RAQPRD family 20 112 4.2E-32 T 28-03-2018 IPR019110 Uncharacterised protein family, RAQPRD WM46_RS15525 7db829023da510a0b58877ff3094a32e 115 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 31 110 1.2E-31 T 28-03-2018 IPR019110 Uncharacterised protein family, RAQPRD WM46_RS22130 023c64c44f9c6672235798b2b7c4223b 83 Gene3D G3DSA:1.10.1200.10 2 83 8.8E-14 T 28-03-2018 WM46_RS22130 023c64c44f9c6672235798b2b7c4223b 83 SUPERFAMILY SSF47336 4 81 9.03E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS22130 023c64c44f9c6672235798b2b7c4223b 83 Pfam PF00550 Phosphopantetheine attachment site 10 75 6.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS18530 0e280861e033d925ad85eefae2fa8405 224 Gene3D G3DSA:2.40.33.20 1 224 2.8E-52 T 28-03-2018 WM46_RS18530 0e280861e033d925ad85eefae2fa8405 224 Pfam PF03475 3-alpha domain 169 212 9.5E-15 T 28-03-2018 IPR005163 3-alpha domain WM46_RS18530 0e280861e033d925ad85eefae2fa8405 224 Pfam PF03473 MOSC domain 47 159 9.0E-21 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 WM46_RS18530 0e280861e033d925ad85eefae2fa8405 224 SUPERFAMILY SSF50800 3 223 1.67E-76 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 SUPERFAMILY SSF51011 475 549 2.09E-18 T 28-03-2018 WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 Pfam PF00128 Alpha amylase, catalytic domain 30 372 3.1E-126 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 SUPERFAMILY SSF51445 5 472 1.76E-154 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 Gene3D G3DSA:2.60.40.1180 476 551 1.4E-17 T 28-03-2018 WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 Gene3D G3DSA:3.20.20.80 4 475 4.1E-129 T 28-03-2018 WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 Pfam PF11941 Domain of unknown function (DUF3459) 459 548 1.5E-8 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 7 549 8.6E-262 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 WM46_RS23270 06a0a5a8c3e10ae1feef0058e8296638 551 SMART SM00642 15 414 3.5E-151 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Gene3D G3DSA:3.30.1360.120 1 121 1.7E-40 T 28-03-2018 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 454 33.193 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 120 3.7E-34 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Gene3D G3DSA:1.20.120.430 122 279 1.9E-26 T 28-03-2018 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Pfam PF01926 50S ribosome-binding GTPase 218 335 9.1E-25 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 370 1.5E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 454 1.5E-98 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 SUPERFAMILY SSF52540 72 152 6.9E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 SUPERFAMILY SSF52540 188 372 6.9E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Gene3D G3DSA:1.20.120.430 280 454 7.0E-34 T 28-03-2018 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 Pfam PF12631 MnmE helical domain 123 451 1.6E-60 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 SUPERFAMILY SSF116878 379 454 6.28E-51 T 28-03-2018 WM46_RS19625 256eb4f13bf60a43d465a55095d9db92 454 SUPERFAMILY SSF116878 121 220 6.28E-51 T 28-03-2018 WM46_RS23020 06dc0f31d07243029a704d4cf99504e5 220 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 14 122 3.8E-22 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM46_RS23020 06dc0f31d07243029a704d4cf99504e5 220 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 131 217 4.8E-28 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM46_RS23020 06dc0f31d07243029a704d4cf99504e5 220 SUPERFAMILY SSF54534 22 219 9.62E-56 T 28-03-2018 WM46_RS23020 06dc0f31d07243029a704d4cf99504e5 220 Gene3D G3DSA:3.10.50.40 105 220 8.5E-41 T 28-03-2018 WM46_RS23020 06dc0f31d07243029a704d4cf99504e5 220 Gene3D G3DSA:1.10.287.460 10 104 2.3E-18 T 28-03-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 WM46_RS00160 d56357d63172949842bce30332d385b3 292 SUPERFAMILY SSF111331 7 289 1.44E-92 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain WM46_RS00160 d56357d63172949842bce30332d385b3 292 Pfam PF01513 ATP-NAD kinase 8 271 1.8E-79 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 WM46_RS00160 d56357d63172949842bce30332d385b3 292 Hamap MF_00361 NAD kinase [nadK]. 6 287 33.2 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 WM46_RS00160 d56357d63172949842bce30332d385b3 292 Gene3D G3DSA:2.60.200.30 142 264 7.9E-41 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 WM46_RS00160 d56357d63172949842bce30332d385b3 292 Gene3D G3DSA:3.40.50.10330 1 141 3.8E-39 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 WM46_RS11140 941db7079151ef13f5c88ccc76f24f33 143 Pfam PF14534 Domain of unknown function (DUF4440) 29 133 7.0E-9 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 WM46_RS11140 941db7079151ef13f5c88ccc76f24f33 143 Gene3D G3DSA:3.10.450.50 19 138 1.3E-13 T 28-03-2018 WM46_RS11140 941db7079151ef13f5c88ccc76f24f33 143 SUPERFAMILY SSF54427 22 140 1.32E-17 T 28-03-2018 IPR032710 NTF2-like domain WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 PIRSF PIRSF000525 1 362 3.3E-147 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 208 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 360 1.5E-152 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 SUPERFAMILY SSF53383 4 360 9.64E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 Gene3D G3DSA:3.40.640.10 16 259 3.4E-21 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 Gene3D G3DSA:3.90.1150.10 260 360 4.3E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 361 50.861 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 WM46_RS09870 945b66a2aa49feafe5ce934d30424bef 362 Pfam PF00266 Aminotransferase class-V 4 350 1.7E-70 T 28-03-2018 IPR000192 Aminotransferase class V domain WM46_RS20005 2869104df07cab61741ebcb8692ca9f1 70 SUPERFAMILY SSF159871 4 70 1.02E-13 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS20005 2869104df07cab61741ebcb8692ca9f1 70 Pfam PF07338 Protein of unknown function (DUF1471) 24 70 1.2E-10 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS20005 2869104df07cab61741ebcb8692ca9f1 70 Gene3D G3DSA:3.30.1660.10 9 70 6.9E-15 T 28-03-2018 IPR025543 Dodecin-like WM46_RS09985 28b766a224d4c30e3e86b65883feb6d2 286 Pfam PF02678 Pirin 21 127 1.6E-34 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 WM46_RS09985 28b766a224d4c30e3e86b65883feb6d2 286 Gene3D G3DSA:2.60.120.10 1 257 7.1E-83 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS09985 28b766a224d4c30e3e86b65883feb6d2 286 Pfam PF05726 Pirin C-terminal cupin domain 182 284 5.0E-31 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 WM46_RS09985 28b766a224d4c30e3e86b65883feb6d2 286 PIRSF PIRSF006232 3 286 1.1E-89 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 WM46_RS09985 28b766a224d4c30e3e86b65883feb6d2 286 SUPERFAMILY SSF51182 2 285 2.96E-82 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS18395 1e960e07bb04797fe1b9716c3008bd87 327 TIGRFAM TIGR02223 ftsN: cell division protein FtsN 2 323 2.1E-95 T 28-03-2018 IPR011930 Cell division protein FtsN GO:0005515 WM46_RS18395 1e960e07bb04797fe1b9716c3008bd87 327 Pfam PF05036 Sporulation related domain 254 321 1.9E-16 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS18395 1e960e07bb04797fe1b9716c3008bd87 327 Hamap MF_02039 Cell division protein FtsN [ftsN]. 36 327 34.62 T 28-03-2018 IPR011930 Cell division protein FtsN GO:0005515 WM46_RS18395 1e960e07bb04797fe1b9716c3008bd87 327 Gene3D G3DSA:3.30.70.1070 249 324 5.1E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS18395 1e960e07bb04797fe1b9716c3008bd87 327 SUPERFAMILY SSF110997 252 323 2.35E-19 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS16405 1a9552648067b4696e721b38ce7d52a1 433 Gene3D G3DSA:1.20.1250.20 1 202 1.2E-39 T 28-03-2018 WM46_RS16405 1a9552648067b4696e721b38ce7d52a1 433 Gene3D G3DSA:1.20.1250.20 214 420 1.7E-23 T 28-03-2018 WM46_RS16405 1a9552648067b4696e721b38ce7d52a1 433 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 17 411 1.1E-126 T 28-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS16405 1a9552648067b4696e721b38ce7d52a1 433 Pfam PF07690 Major Facilitator Superfamily 301 419 3.3E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS16405 1a9552648067b4696e721b38ce7d52a1 433 Pfam PF07690 Major Facilitator Superfamily 16 287 6.9E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS16405 1a9552648067b4696e721b38ce7d52a1 433 SUPERFAMILY SSF103473 3 412 6.02E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS21655 14f5162a4c3f7ea239e0247a6303342f 116 SUPERFAMILY SSF142906 1 115 3.79E-35 T 28-03-2018 WM46_RS21655 14f5162a4c3f7ea239e0247a6303342f 116 Pfam PF04237 YjbR 13 101 3.1E-17 T 28-03-2018 IPR007351 Uncharacterised protein YjbR WM46_RS11480 f712d4ad661a5d77da3ebf7c0a12ceb5 98 Hamap MF_00805 Citrate lyase acyl carrier protein [citD]. 1 97 26.645 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 WM46_RS11480 f712d4ad661a5d77da3ebf7c0a12ceb5 98 ProDom PD015389 LYASE CITRATE ACYL CARRIER GAMMA CHAIN CITD PRECURSOR SIGNAL DIRECT 1 74 1.0E-33 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 WM46_RS11480 f712d4ad661a5d77da3ebf7c0a12ceb5 98 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 5 86 5.0E-29 T 28-03-2018 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein WM46_RS11480 f712d4ad661a5d77da3ebf7c0a12ceb5 98 TIGRFAM TIGR01608 citD: citrate lyase acyl carrier protein 1 94 1.7E-29 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 WM46_RS11480 f712d4ad661a5d77da3ebf7c0a12ceb5 98 PIRSF PIRSF002736 1 97 3.1E-39 T 28-03-2018 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 WM46_RS01550 5ea0d25f1d6d8c0bc416668985c3694a 392 Pfam PF07690 Major Facilitator Superfamily 223 389 9.0E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS01550 5ea0d25f1d6d8c0bc416668985c3694a 392 Gene3D G3DSA:1.20.1250.20 211 391 2.0E-20 T 28-03-2018 WM46_RS01550 5ea0d25f1d6d8c0bc416668985c3694a 392 SUPERFAMILY SSF103473 14 391 3.27E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS01550 5ea0d25f1d6d8c0bc416668985c3694a 392 Gene3D G3DSA:1.20.1250.20 9 204 2.5E-17 T 28-03-2018 WM46_RS08975 b0d73833f9728ed128a7d2c923b8aad0 179 Pfam PF06496 Protein of unknown function (DUF1097) 24 157 2.7E-37 T 28-03-2018 IPR009476 Protein of unknown function DUF1097 WM46_RS20320 771fd66668640791b7849e6671fadb36 68 SUPERFAMILY SSF46575 15 64 8.11E-7 T 28-03-2018 WM46_RS20320 771fd66668640791b7849e6671fadb36 68 Gene3D G3DSA:1.20.970.20 14 63 1.5E-17 T 28-03-2018 WM46_RS20105 1b826454d2b43f33d2c2885f19c6f110 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 1.7E-43 T 28-03-2018 IPR013527 YicC-like, N-terminal WM46_RS20105 1b826454d2b43f33d2c2885f19c6f110 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 2.0E-137 T 28-03-2018 IPR005229 Conserved hypothetical protein CHP00255 WM46_RS20105 1b826454d2b43f33d2c2885f19c6f110 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 1.8E-34 T 28-03-2018 IPR013551 Domain of unknown function DUF1732 WM46_RS02005 7312fd064a5fafc2824e1521debd4a3b 242 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 16 234 2.1E-90 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 WM46_RS02005 7312fd064a5fafc2824e1521debd4a3b 242 Pfam PF13489 Methyltransferase domain 57 170 2.5E-24 T 28-03-2018 WM46_RS02005 7312fd064a5fafc2824e1521debd4a3b 242 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 14 240 37.986 T 28-03-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 WM46_RS02005 7312fd064a5fafc2824e1521debd4a3b 242 Gene3D G3DSA:3.40.50.150 5 240 1.5E-44 T 28-03-2018 WM46_RS02005 7312fd064a5fafc2824e1521debd4a3b 242 SUPERFAMILY SSF53335 17 223 1.57E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS16140 21ccd51b7a571567deb92136b706db76 221 Hamap MF_01188 UPF0441 protein YgiB [ygiB]. 1 221 36.552 T 28-03-2018 IPR009576 Biofilm formation YgiB WM46_RS16140 21ccd51b7a571567deb92136b706db76 221 Pfam PF06693 Protein of unknown function (DUF1190) 41 208 3.5E-57 T 28-03-2018 IPR009576 Biofilm formation YgiB WM46_RS17625 7eab43b5bf468377aa1b164beb2126a9 198 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 136 2.7E-9 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain WM46_RS17625 7eab43b5bf468377aa1b164beb2126a9 198 Gene3D G3DSA:3.10.50.40 1 164 1.2E-29 T 28-03-2018 WM46_RS17625 7eab43b5bf468377aa1b164beb2126a9 198 SUPERFAMILY SSF54534 2 140 2.16E-33 T 28-03-2018 WM46_RS01625 7efb5902d37a2fa128f8340ad694536f 228 Gene3D G3DSA:1.10.3720.10 3 224 1.7E-37 T 28-03-2018 WM46_RS01625 7efb5902d37a2fa128f8340ad694536f 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 114 5.9E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS01625 7efb5902d37a2fa128f8340ad694536f 228 SUPERFAMILY SSF161098 7 205 5.63E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01625 7efb5902d37a2fa128f8340ad694536f 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 219 3.6E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.10 192 276 7.8E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 723 807 1.2E-11 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 892 999 1.5E-23 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1097 1202 5.4E-22 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 2086 2192 1.4E-22 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1885 1985 1.0E-26 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1779 1884 1.2E-24 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1297 1389 3.7E-27 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 2501 2596 2.0E-16 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1390 1474 1.3E-15 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1986 2085 2.9E-23 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1475 1590 5.7E-12 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 552 637 3.3E-16 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 2193 2295 3.5E-25 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 2597 2722 5.7E-17 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 277 381 2.0E-16 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1203 1296 3.8E-19 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 638 722 2.7E-14 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 808 891 2.5E-15 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1591 1676 2.8E-10 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1677 1778 3.2E-21 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 2402 2500 2.5E-21 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 1000 1096 4.7E-18 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.1310 2296 2401 2.4E-21 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.120.640 2848 2969 4.0E-8 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.120.640 3105 3221 7.4E-7 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.120.640 3373 3480 1.5E-11 T 28-03-2018 WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.10 476 551 1.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.10 383 475 1.0E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 3500 3577 3.9E-17 T 28-03-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2880 2923 0.0016 T 28-03-2018 IPR010221 VCBS repeat WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 3401 3459 3.4E-4 T 28-03-2018 IPR010221 VCBS repeat WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Pfam PF12245 Bacterial Ig-like domain (group 3) 2485 2509 0.097 T 28-03-2018 IPR022038 Bacterial Ig-like domain WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Pfam PF12245 Bacterial Ig-like domain (group 3) 2400 2425 0.079 T 28-03-2018 IPR022038 Bacterial Ig-like domain WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Pfam PF12245 Bacterial Ig-like domain (group 3) 1206 1226 2.1 T 28-03-2018 IPR022038 Bacterial Ig-like domain WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Pfam PF12245 Bacterial Ig-like domain (group 3) 2183 2218 0.063 T 28-03-2018 IPR022038 Bacterial Ig-like domain WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Pfam PF12245 Bacterial Ig-like domain (group 3) 1385 1410 0.19 T 28-03-2018 IPR022038 Bacterial Ig-like domain WM46_RS00130 8d4abfd2d2a3584d6dd95d704036e701 3581 Gene3D G3DSA:2.60.40.10 3271 3333 8.5E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS06830 31bfa205e30511c316333ad5e5c213d3 143 Pfam PF02566 OsmC-like protein 43 138 3.0E-19 T 28-03-2018 IPR003718 OsmC/Ohr family WM46_RS06830 31bfa205e30511c316333ad5e5c213d3 143 SUPERFAMILY SSF82784 1 141 1.83E-41 T 28-03-2018 IPR003718 OsmC/Ohr family WM46_RS06830 31bfa205e30511c316333ad5e5c213d3 143 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 2.7E-61 T 28-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 WM46_RS06830 31bfa205e30511c316333ad5e5c213d3 143 Gene3D G3DSA:3.30.300.20 2 143 1.3E-30 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 SUPERFAMILY SSF51735 1 167 8.88E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 168 289 2.6E-37 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 Gene3D G3DSA:1.10.1040.10 168 296 5.9E-39 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 143 5.2E-25 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 SUPERFAMILY SSF48179 168 289 6.46E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 Gene3D G3DSA:3.40.50.720 1 167 3.6E-24 T 28-03-2018 WM46_RS12700 65289ebc8d7f67904048247f9d122ce6 303 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 1.4E-76 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 Pfam PF00072 Response regulator receiver domain 6 113 8.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 SUPERFAMILY SSF46894 136 234 7.65E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 Gene3D G3DSA:3.40.50.2300 1 136 9.9E-32 T 28-03-2018 WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 SMART SM00448 4 114 6.3E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 SMART SM00862 156 232 3.7E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 Gene3D G3DSA:1.10.10.10 137 238 1.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 SUPERFAMILY SSF52172 2 126 2.85E-36 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS14830 c309dbeeec353a760a85ac406ec782f5 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 2.5E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS10355 36c5bae754b743d69a27c5811b0fc96b 306 Pfam PF03734 L,D-transpeptidase catalytic domain 101 231 1.8E-17 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 WM46_RS10355 36c5bae754b743d69a27c5811b0fc96b 306 SUPERFAMILY SSF141523 177 233 2.49E-26 T 28-03-2018 WM46_RS10355 36c5bae754b743d69a27c5811b0fc96b 306 SUPERFAMILY SSF141523 99 149 2.49E-26 T 28-03-2018 WM46_RS10355 36c5bae754b743d69a27c5811b0fc96b 306 Gene3D G3DSA:2.40.440.10 94 233 4.6E-28 T 28-03-2018 WM46_RS11730 8ea40b4edff78c1bcae6926ef0d02b4d 234 Pfam PF13302 Acetyltransferase (GNAT) domain 36 173 3.4E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS11730 8ea40b4edff78c1bcae6926ef0d02b4d 234 Gene3D G3DSA:3.40.630.30 16 206 7.2E-29 T 28-03-2018 WM46_RS11730 8ea40b4edff78c1bcae6926ef0d02b4d 234 SUPERFAMILY SSF55729 26 198 8.31E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS20950 af7b5d2497f7679a6f8493a6eabb5efd 359 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 10 335 2.4E-90 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 WM46_RS04120 58dfb5ceab4dc1e7fe99f2d9b3182995 309 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 13 66 1.4E-20 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain WM46_RS04120 58dfb5ceab4dc1e7fe99f2d9b3182995 309 SUPERFAMILY SSF103088 157 265 2.09E-19 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS04120 58dfb5ceab4dc1e7fe99f2d9b3182995 309 Pfam PF00691 OmpA family 161 258 3.3E-13 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS04120 58dfb5ceab4dc1e7fe99f2d9b3182995 309 Gene3D G3DSA:3.30.1330.60 108 296 1.2E-41 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS19920 eccc82ffec77aeed23e033cc79cf9e1c 138 Pfam PF00583 Acetyltransferase (GNAT) family 36 115 8.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS19920 eccc82ffec77aeed23e033cc79cf9e1c 138 Gene3D G3DSA:3.40.630.30 35 137 2.6E-14 T 28-03-2018 WM46_RS19920 eccc82ffec77aeed23e033cc79cf9e1c 138 SUPERFAMILY SSF55729 25 127 2.36E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS08780 3a2351b7520ee30aa96a8338b959d5b3 232 Pfam PF13860 FlgD Ig-like domain 119 189 1.7E-23 T 28-03-2018 IPR025965 FlgD Ig-like domain WM46_RS08780 3a2351b7520ee30aa96a8338b959d5b3 232 Pfam PF03963 Flagellar hook capping protein - N-terminal region 12 80 7.0E-24 T 28-03-2018 IPR005648 Flagellar hook capping protein WM46_RS08780 3a2351b7520ee30aa96a8338b959d5b3 232 Pfam PF13861 FlgD Tudor-like domain 88 229 1.5E-15 T 28-03-2018 IPR025963 FlgD Tudor-like domain WM46_RS02515 3b474ad4c707d98d398568aee79ab528 233 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 228 9.2E-50 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS02515 3b474ad4c707d98d398568aee79ab528 233 Gene3D G3DSA:3.90.850.10 2 233 3.7E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS02515 3b474ad4c707d98d398568aee79ab528 233 SUPERFAMILY SSF56529 22 233 3.14E-65 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS07680 272f164b8de3618db7d07a719bfcb12b 299 SUPERFAMILY SSF49401 114 299 3.48E-8 T 28-03-2018 IPR008966 Adhesion domain WM46_RS07680 272f164b8de3618db7d07a719bfcb12b 299 Gene3D G3DSA:2.60.40.1090 121 299 2.3E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS07680 272f164b8de3618db7d07a719bfcb12b 299 Pfam PF00419 Fimbrial protein 118 298 3.1E-8 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24290 2eca9815aefde3fdf45d67dbed07364b 482 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 440 6.1E-136 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS24290 2eca9815aefde3fdf45d67dbed07364b 482 TIGRFAM TIGR03173 pbuX: xanthine permease 33 443 9.6E-154 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 WM46_RS24290 2eca9815aefde3fdf45d67dbed07364b 482 Pfam PF00860 Permease family 29 408 3.2E-121 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS24290 2eca9815aefde3fdf45d67dbed07364b 482 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 357 377 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS22215 7f6db71f97b580a998dd89f1eda8bbeb 160 Gene3D G3DSA:3.40.630.30 7 158 4.4E-13 T 28-03-2018 WM46_RS22215 7f6db71f97b580a998dd89f1eda8bbeb 160 SUPERFAMILY SSF55729 19 149 1.47E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS22215 7f6db71f97b580a998dd89f1eda8bbeb 160 Pfam PF00583 Acetyltransferase (GNAT) family 39 146 1.2E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS02635 541970c93855a41039109687461f6505 94 ProDom PD064930 YEHE MEMBRANE OUTER STY2382 PRECURSOR ECS2918 SIGNAL 1 84 4.0E-21 T 28-03-2018 IPR020386 Uncharacterised protein family YehE WM46_RS02635 541970c93855a41039109687461f6505 94 Pfam PF10836 Protein of unknown function (DUF2574) 1 94 1.6E-41 T 28-03-2018 IPR020386 Uncharacterised protein family YehE WM46_RS21535 cba9ad72b715e24ca7c4469a0a587a6f 136 Pfam PF06146 Phosphate-starvation-inducible E 63 123 1.7E-16 T 28-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like WM46_RS21535 cba9ad72b715e24ca7c4469a0a587a6f 136 PIRSF PIRSF029598 1 136 9.7E-53 T 28-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 WM46_RS21535 cba9ad72b715e24ca7c4469a0a587a6f 136 Hamap MF_01048 Protein PsiE [psiE]. 3 136 25.322 T 28-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 WM46_RS01420 b69a28d080c775a99e15af8341a9c97c 195 Gene3D G3DSA:3.40.50.1820 2 194 5.8E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS01420 b69a28d080c775a99e15af8341a9c97c 195 SUPERFAMILY SSF53474 7 191 6.34E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS01420 b69a28d080c775a99e15af8341a9c97c 195 Pfam PF01738 Dienelactone hydrolase family 5 190 1.7E-19 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 WM46_RS11945 0dfa9be636e6b1693326394813acc676 180 Pfam PF13521 AAA domain 8 172 7.7E-39 T 28-03-2018 WM46_RS11945 0dfa9be636e6b1693326394813acc676 180 Gene3D G3DSA:3.40.50.300 7 177 8.2E-12 T 28-03-2018 WM46_RS11945 0dfa9be636e6b1693326394813acc676 180 SUPERFAMILY SSF52540 9 175 7.74E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS04455 755519edfe5867bfa1d448a53cb09e3f 98 Pfam PF14359 Domain of unknown function (DUF4406) 3 92 1.8E-32 T 28-03-2018 IPR025518 Protein of unknown function DUF4406 WM46_RS04455 755519edfe5867bfa1d448a53cb09e3f 98 SUPERFAMILY SSF52309 2 94 4.58E-26 T 28-03-2018 WM46_RS04455 755519edfe5867bfa1d448a53cb09e3f 98 Gene3D G3DSA:3.40.50.10400 1 98 3.6E-26 T 28-03-2018 IPR027269 Hypothetical PA1492 domain WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 2.5E-66 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 Gene3D G3DSA:3.90.45.10 1 169 6.4E-62 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 PRINTS PR01576 Peptide deformylase signature 101 119 6.7E-39 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 PRINTS PR01576 Peptide deformylase signature 120 149 6.7E-39 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 PRINTS PR01576 Peptide deformylase signature 89 100 6.7E-39 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 PRINTS PR01576 Peptide deformylase signature 33 62 6.7E-39 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 Pfam PF01327 Polypeptide deformylase 4 152 3.9E-51 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 PIRSF PIRSF004749 1 168 2.6E-55 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 SUPERFAMILY SSF56420 3 164 1.02E-61 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS17375 7544b8400aa1922223eca383f7a1816a 169 Hamap MF_00163 Peptide deformylase [def]. 2 162 32.062 T 28-03-2018 IPR023635 Peptide deformylase WM46_RS11770 bb92f660b3bceeab83faeeb106e5b981 217 Gene3D G3DSA:3.40.109.10 1 217 7.5E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS11770 bb92f660b3bceeab83faeeb106e5b981 217 SUPERFAMILY SSF55469 1 216 2.49E-64 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 WM46_RS11770 bb92f660b3bceeab83faeeb106e5b981 217 Pfam PF00881 Nitroreductase family 8 193 3.4E-33 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 WM46_RS15355 03e00d9c80244a54d9d72e143bf8910c 203 Pfam PF02525 Flavodoxin-like fold 1 200 8.8E-43 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS15355 03e00d9c80244a54d9d72e143bf8910c 203 SUPERFAMILY SSF52218 1 201 1.48E-48 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS15355 03e00d9c80244a54d9d72e143bf8910c 203 Gene3D G3DSA:3.40.50.360 1 203 1.6E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS15355 03e00d9c80244a54d9d72e143bf8910c 203 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 202 30.166 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 WM46_RS12150 db81bf05cf70d9d73062d3ac02423c73 67 Pfam PF13132 Domain of unknown function (DUF3950) 21 54 6.1E-8 T 28-03-2018 IPR025030 Domain of unknown function DUF3950 WM46_RS09975 7685e403ced062aa096db5195bf558e7 72 Gene3D G3DSA:2.40.50.140 1 72 7.1E-36 T 28-03-2018 WM46_RS09975 7685e403ced062aa096db5195bf558e7 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 5.1E-39 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 WM46_RS09975 7685e403ced062aa096db5195bf558e7 72 SUPERFAMILY SSF50249 1 70 5.36E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS09975 7685e403ced062aa096db5195bf558e7 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.2E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 WM46_RS09975 7685e403ced062aa096db5195bf558e7 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.442 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 WM46_RS09975 7685e403ced062aa096db5195bf558e7 72 SMART SM00316 4 72 2.8E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS22285 c36fcc00ee433fece91cadc39dc26bb5 237 TIGRFAM TIGR03759 conj_TIGR03759: integrating conjugative element protein, PFL_4693 family 40 233 1.1E-82 T 28-03-2018 IPR022293 Integrating conjugative element protein, PFL4693 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 SUPERFAMILY SSF68923 8 226 2.09E-91 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 Pfam PF01293 Phosphoenolpyruvate carboxykinase 21 490 3.6E-212 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 15 537 55.994 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 PIRSF PIRSF006294 2 539 3.1E-233 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 Gene3D G3DSA:3.90.228.20 308 537 5.8E-93 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 Gene3D G3DSA:3.90.228.20 227 307 6.0E-29 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 SUPERFAMILY SSF53795 228 539 1.63E-130 T 28-03-2018 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 Gene3D G3DSA:3.40.449.10 22 226 3.5E-78 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 7 539 1.8E-291 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 WM46_RS17845 45d85657ead3fad92c08a7f9a204e6ac 539 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 264 279 - T 28-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 390 5.8E-131 T 28-03-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 Pfam PF01494 FAD binding domain 6 339 2.3E-28 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 SUPERFAMILY SSF51905 267 383 7.56E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 SUPERFAMILY SSF51905 5 178 7.56E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 1.7E-18 T 28-03-2018 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 1.7E-18 T 28-03-2018 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.7E-18 T 28-03-2018 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.7E-18 T 28-03-2018 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 Gene3D G3DSA:3.50.50.60 4 363 2.5E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11290 31db86bbf307994f600a4354014f7028 391 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 294 307 - T 28-03-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 WM46_RS18575 5c0c9de61a5bc5b65519e20813e97976 275 SUPERFAMILY SSF53639 1 272 4.51E-76 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS18575 5c0c9de61a5bc5b65519e20813e97976 275 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 238 2.0E-35 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS18575 5c0c9de61a5bc5b65519e20813e97976 275 SMART SM01007 11 239 2.5E-31 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS18575 5c0c9de61a5bc5b65519e20813e97976 275 Hamap MF_00770 Rhamnulose-1-phosphate aldolase [rhaD]. 1 272 58.072 T 28-03-2018 IPR013447 Rhamnulose-1-phosphate aldolase GO:0008994|GO:0019301 KEGG: 00040+4.1.2.19|KEGG: 00051+4.1.2.19 WM46_RS18575 5c0c9de61a5bc5b65519e20813e97976 275 Gene3D G3DSA:3.40.225.10 4 256 8.3E-50 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS18575 5c0c9de61a5bc5b65519e20813e97976 275 TIGRFAM TIGR02624 rhamnu_1P_ald: rhamnulose-1-phosphate aldolase 1 272 2.0E-137 T 28-03-2018 IPR013447 Rhamnulose-1-phosphate aldolase GO:0008994|GO:0019301 KEGG: 00040+4.1.2.19|KEGG: 00051+4.1.2.19 WM46_RS11855 5db52a7339b4e93749d9311b17b15785 460 Gene3D G3DSA:1.20.1600.10 18 460 2.5E-95 T 28-03-2018 WM46_RS11855 5db52a7339b4e93749d9311b17b15785 460 Pfam PF02321 Outer membrane efflux protein 274 455 1.2E-26 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS11855 5db52a7339b4e93749d9311b17b15785 460 Pfam PF02321 Outer membrane efflux protein 65 247 4.8E-22 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS11855 5db52a7339b4e93749d9311b17b15785 460 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 457 4.1E-109 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 WM46_RS11855 5db52a7339b4e93749d9311b17b15785 460 SUPERFAMILY SSF56954 2 458 2.88E-103 T 28-03-2018 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 Gene3D G3DSA:1.20.1080.10 1 259 1.3E-77 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 Pfam PF00230 Major intrinsic protein 2 251 1.0E-74 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 TIGRFAM TIGR00861 MIP: MIP family channel proteins 13 251 3.4E-74 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 ProSitePatterns PS00221 MIP family signature. 66 74 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 SUPERFAMILY SSF81338 9 257 1.57E-78 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 PRINTS PR00783 Major intrinsic protein family signature 234 254 2.0E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 PRINTS PR00783 Major intrinsic protein family signature 85 104 2.0E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 PRINTS PR00783 Major intrinsic protein family signature 9 28 2.0E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 PRINTS PR00783 Major intrinsic protein family signature 48 72 2.0E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 PRINTS PR00783 Major intrinsic protein family signature 184 206 2.0E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS18430 cdcd83ade306c61f41237cade6856843 281 PRINTS PR00783 Major intrinsic protein family signature 151 169 2.0E-51 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 SUPERFAMILY SSF46911 3 74 7.06E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 8.1E-38 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.3E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.3E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.3E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.3E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 3.0E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 Pfam PF01084 Ribosomal protein S18 19 68 9.1E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 21.313 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS22995 4d776f2becc435db4210658806b3f9df 75 Gene3D G3DSA:4.10.640.10 1 75 1.5E-31 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS06565 774f88d03045fa0123b40cdd69d64f3e 314 SUPERFAMILY SSF161098 32 308 2.22E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06565 774f88d03045fa0123b40cdd69d64f3e 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 308 1.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06565 774f88d03045fa0123b40cdd69d64f3e 314 Gene3D G3DSA:1.10.3720.10 29 310 1.3E-34 T 28-03-2018 WM46_RS24850 7b905be5f1eedc559d4bb959f5235dcb 231 SUPERFAMILY SSF52980 10 227 4.66E-78 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 WM46_RS24850 7b905be5f1eedc559d4bb959f5235dcb 231 Gene3D G3DSA:3.40.600.10 10 229 1.1E-55 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 WM46_RS24850 7b905be5f1eedc559d4bb959f5235dcb 231 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 231 154.772 T 28-03-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 WM46_RS24850 7b905be5f1eedc559d4bb959f5235dcb 231 Pfam PF02976 DNA mismatch repair enzyme MutH 59 157 3.0E-33 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 WM46_RS24850 7b905be5f1eedc559d4bb959f5235dcb 231 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 11 226 3.1E-112 T 28-03-2018 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 WM46_RS24850 7b905be5f1eedc559d4bb959f5235dcb 231 SMART SM00927 59 157 8.7E-64 T 28-03-2018 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 WM46_RS09480 dfb43d7d416c90f60fb617af50c1bea2 74 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 67 1.8E-21 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS09480 dfb43d7d416c90f60fb617af50c1bea2 74 Gene3D G3DSA:1.10.260.40 2 73 7.0E-11 T 28-03-2018 WM46_RS09480 dfb43d7d416c90f60fb617af50c1bea2 74 SMART SM00530 6 62 1.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS09480 dfb43d7d416c90f60fb617af50c1bea2 74 SUPERFAMILY SSF47413 1 67 1.47E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 SUPERFAMILY SSF48208 9 351 3.74E-103 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 Gene3D G3DSA:1.50.10.10 22 360 3.3E-99 T 28-03-2018 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 ProSitePatterns PS00812 Glycosyl hydrolases family 8 signature. 114 132 - T 28-03-2018 IPR019834 Glycoside hydrolase, family 8, conserved site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 Pfam PF01270 Glycosyl hydrolases family 8 1 346 1.4E-133 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 114 132 8.3E-21 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 240 249 8.3E-21 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 215 226 8.3E-21 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 52 65 8.3E-21 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 179 196 8.3E-21 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS20670 9226c7efbb81dbf1b8fab3949941be7f 368 PRINTS PR00735 Glycosyl hydrolase family 8 signature 331 345 8.3E-21 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 WM46_RS17620 9c4e4d6331d5405324c8ec6b9ce0e031 72 Hamap MF_00715 Protein SlyX [slyX]. 5 72 17.078 T 28-03-2018 IPR007236 SlyX WM46_RS17620 9c4e4d6331d5405324c8ec6b9ce0e031 72 Pfam PF04102 SlyX 6 72 1.2E-23 T 28-03-2018 IPR007236 SlyX WM46_RS17620 9c4e4d6331d5405324c8ec6b9ce0e031 72 Gene3D G3DSA:1.20.5.300 4 50 1.6E-16 T 28-03-2018 WM46_RS12020 561563858177e685ea219b8c4eff5b89 176 Gene3D G3DSA:2.60.40.1090 26 176 6.0E-36 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS12020 561563858177e685ea219b8c4eff5b89 176 SUPERFAMILY SSF49401 27 176 3.83E-37 T 28-03-2018 IPR008966 Adhesion domain WM46_RS12020 561563858177e685ea219b8c4eff5b89 176 Pfam PF00419 Fimbrial protein 29 175 9.6E-17 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 366 42.531 T 28-03-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 10 365 1.1E-189 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 299 328 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 10 365 2.2E-185 T 28-03-2018 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 Gene3D G3DSA:3.40.50.150 156 366 5.2E-35 T 28-03-2018 WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 SUPERFAMILY SSF53335 6 363 8.96E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS21070 f3de999bd0b630067bc9824a54e6fc4b 366 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 348 358 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site WM46_RS16420 05d2fd68f3b149f0b1a474e0b706e532 127 Pfam PF13721 SecD export protein N-terminal TM region 17 104 5.1E-16 T 28-03-2018 IPR027398 SecD export protein N-terminal TM domain WM46_RS16420 05d2fd68f3b149f0b1a474e0b706e532 127 Hamap MF_00904 Modulator protein MzrA [mzrA]. 2 116 29.285 T 28-03-2018 IPR026574 Modulator protein MzrA WM46_RS24585 1f50625019bebab5fffe7e194f965879 473 Gene3D G3DSA:3.20.20.450 222 471 2.1E-47 T 28-03-2018 IPR001633 EAL domain WM46_RS24585 1f50625019bebab5fffe7e194f965879 473 SMART SM00052 220 462 2.3E-46 T 28-03-2018 IPR001633 EAL domain WM46_RS24585 1f50625019bebab5fffe7e194f965879 473 Pfam PF00563 EAL domain 226 457 4.9E-46 T 28-03-2018 IPR001633 EAL domain WM46_RS24585 1f50625019bebab5fffe7e194f965879 473 SUPERFAMILY SSF141868 226 468 5.89E-47 T 28-03-2018 IPR001633 EAL domain WM46_RS08965 2da4b62729369ef466e39c02599d99b7 138 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 6 129 1.4E-36 T 28-03-2018 IPR018893 Type VIII secretion system, CsgF WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 SUPERFAMILY SSF103661 465 497 7.98E-13 T 28-03-2018 IPR015041 Osmosensory transporter coiled coil WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 Gene3D G3DSA:1.20.1250.20 23 237 3.9E-23 T 28-03-2018 WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 Gene3D G3DSA:1.20.1250.20 240 488 1.9E-28 T 28-03-2018 WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 Pfam PF00083 Sugar (and other) transporter 28 448 1.9E-72 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 SUPERFAMILY SSF103473 24 440 1.83E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 33 431 7.5E-146 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 WM46_RS21925 2bc77171fcfb5179a3cd92a11028ea70 500 Pfam PF08946 Osmosensory transporter coiled coil 454 499 7.5E-23 T 28-03-2018 IPR015041 Osmosensory transporter coiled coil WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 Gene3D G3DSA:3.40.50.300 27 179 1.7E-9 T 28-03-2018 WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 SUPERFAMILY SSF52540 32 226 3.95E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 Gene3D G3DSA:1.10.8.60 182 248 1.8E-14 T 28-03-2018 WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 Pfam PF00308 Bacterial dnaA protein 31 227 2.5E-16 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 Hamap MF_01158 DnaA regulatory inactivator Hda [hda]. 20 248 57.785 T 28-03-2018 IPR022864 DnaA regulatory inactivator Hda, Enterobacteriaceae WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 21 247 2.9E-84 T 28-03-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 58 78 2.2E-7 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS00795 fe27dd97b765b3a48f1690b66fe847e5 248 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 146 173 2.2E-7 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 ProSitePatterns PS00356 LacI-type HTH domain signature. 33 51 - T 28-03-2018 WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 Gene3D G3DSA:1.10.10.10 4 68 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 Gene3D G3DSA:3.40.50.10490 69 242 1.7E-26 T 28-03-2018 WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 SUPERFAMILY SSF53697 85 230 2.23E-31 T 28-03-2018 WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 SUPERFAMILY SSF46689 6 73 1.29E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 71 5.6E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 WM46_RS24225 fb344c0ec86ad64fe42fdccca8b17a60 242 Pfam PF01380 SIS domain 108 227 8.1E-15 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS19210 e90ab43b690dc077d366b10a9116fb9e 416 Pfam PF01943 Polysaccharide biosynthesis protein 4 283 7.4E-13 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 WM46_RS19210 e90ab43b690dc077d366b10a9116fb9e 416 Hamap MF_02024 Lipid III flippase [wzxE]. 1 416 40.756 T 28-03-2018 IPR032896 Lipid III flippase WzxE GO:0005886|GO:0009246 WM46_RS15170 03b8880c0da47f257ae6627d599bf022 333 Gene3D G3DSA:1.10.150.130 3 115 1.8E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS15170 03b8880c0da47f257ae6627d599bf022 333 Pfam PF00589 Phage integrase family 115 306 1.9E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS15170 03b8880c0da47f257ae6627d599bf022 333 Gene3D G3DSA:1.10.443.10 116 316 8.3E-29 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS15170 03b8880c0da47f257ae6627d599bf022 333 SUPERFAMILY SSF56349 10 315 9.42E-40 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS15170 03b8880c0da47f257ae6627d599bf022 333 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 16 91 1.0E-6 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 SMART SM00528 87 135 2.4E-25 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 PIRSF PIRSF002096 1 135 5.7E-57 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 SUPERFAMILY SSF81273 2 58 5.1E-18 T 28-03-2018 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 SUPERFAMILY SSF81273 93 136 2.43E-12 T 28-03-2018 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 Gene3D G3DSA:4.10.430.10 93 135 2.0E-19 T 28-03-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 Pfam PF00816 H-NS histone family 32 127 2.7E-20 T 28-03-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 WM46_RS05720 b9966d53324e607b6dbaf3831baf110c 137 Gene3D G3DSA:1.10.287.1050 1 57 9.1E-26 T 28-03-2018 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 WM46_RS02545 cfb5e55c036f8e01e33598bd52104802 195 Pfam PF06930 Protein of unknown function (DUF1282) 7 177 2.0E-45 T 28-03-2018 IPR009698 Protein of unknown function DUF1282 WM46_RS03595 8e0b57a6e2f3744ae388b4ac9ccf2773 264 Pfam PF06180 Cobalt chelatase (CbiK) 3 256 2.6E-103 T 28-03-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 WM46_RS03595 8e0b57a6e2f3744ae388b4ac9ccf2773 264 Gene3D G3DSA:3.40.50.1400 1 123 1.1E-11 T 28-03-2018 WM46_RS03595 8e0b57a6e2f3744ae388b4ac9ccf2773 264 SUPERFAMILY SSF53800 2 256 1.57E-80 T 28-03-2018 WM46_RS03595 8e0b57a6e2f3744ae388b4ac9ccf2773 264 Gene3D G3DSA:3.40.50.1400 124 236 3.0E-22 T 28-03-2018 WM46_RS03595 8e0b57a6e2f3744ae388b4ac9ccf2773 264 PIRSF PIRSF033579 1 264 6.4E-107 T 28-03-2018 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 WM46_RS09970 f978ef008e2dbe0f689fbd97ea3b36b0 234 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 234 97.177 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 WM46_RS09970 f978ef008e2dbe0f689fbd97ea3b36b0 234 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 32 218 5.1E-87 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 WM46_RS09970 f978ef008e2dbe0f689fbd97ea3b36b0 234 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 35 203 9.6E-71 T 28-03-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 WM46_RS09970 f978ef008e2dbe0f689fbd97ea3b36b0 234 SUPERFAMILY SSF55729 2 229 9.53E-93 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS23635 df41d0e936ceaa979f0703d6f2303dc7 73 ProDom PD056719 YEET C0272 C4574 AEC74 ECS1404 C1284 INTERGENIC-REGION YKFH YPJJ 10 73 4.0E-25 T 28-03-2018 IPR009329 Protein of unknown function DUF987 WM46_RS23635 df41d0e936ceaa979f0703d6f2303dc7 73 Pfam PF06174 Protein of unknown function (DUF987) 1 65 2.6E-39 T 28-03-2018 IPR009329 Protein of unknown function DUF987 WM46_RS11735 98d7603ce30ba6d2188d16a1679b96e2 371 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 371 92.565 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM46_RS11735 98d7603ce30ba6d2188d16a1679b96e2 371 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 14 292 1.1E-88 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM46_RS11735 98d7603ce30ba6d2188d16a1679b96e2 371 SUPERFAMILY SSF55931 4 369 5.95E-108 T 28-03-2018 WM46_RS11735 98d7603ce30ba6d2188d16a1679b96e2 371 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 13 295 1.6E-115 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 Gene3D G3DSA:1.10.287.470 110 169 2.7E-11 T 28-03-2018 WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 SUPERFAMILY SSF111369 176 323 5.62E-13 T 28-03-2018 WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 42 318 1.8E-15 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 SUPERFAMILY SSF111369 112 170 5.23E-5 T 28-03-2018 WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 Hamap MF_01304 UPF0194 membrane protein YbhG [ybhG]. 1 327 51.343 T 28-03-2018 IPR022936 Uncharacterised protein family UPF0194, membrane protein YbhG WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 SUPERFAMILY SSF111369 41 98 2.09E-8 T 28-03-2018 WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 Gene3D G3DSA:1.20.1600.10 174 305 3.8E-16 T 28-03-2018 WM46_RS10495 e1a0d38a03008f73c48ba80be6f3012c 331 Gene3D G3DSA:2.40.50.100 42 106 1.3E-14 T 28-03-2018 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 Pfam PF12161 HsdM N-terminal domain 11 148 6.8E-22 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 SUPERFAMILY SSF53335 9 506 1.37E-137 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 287 299 3.1E-15 T 28-03-2018 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 323 347 3.1E-15 T 28-03-2018 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 202 3.1E-15 T 28-03-2018 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 210 224 3.1E-15 T 28-03-2018 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 Pfam PF02384 N-6 DNA Methylase 164 471 1.9E-107 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 Gene3D G3DSA:3.40.50.150 184 465 8.8E-71 T 28-03-2018 WM46_RS03960 471b17a0ba7c12838bbeb48bab54f5de 528 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 9 484 1.2E-84 T 28-03-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 WM46_RS12070 409b54cea64e0751483581158e08985f 165 Pfam PF05119 Phage terminase, small subunit 46 151 2.3E-23 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family WM46_RS12070 409b54cea64e0751483581158e08985f 165 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 37 160 1.3E-32 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family WM46_RS11090 dc13cb8c2b6dbde1d326c3c5d627913d 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 9.9E-10 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 WM46_RS11090 dc13cb8c2b6dbde1d326c3c5d627913d 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 2.4E-6 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 Gene3D G3DSA:2.40.50.140 33 124 2.9E-31 T 28-03-2018 WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 Pfam PF12111 Polyribonucleotide phosphorylase C terminal 1064 1100 2.5E-15 T 28-03-2018 IPR021968 Polyribonucleotide phosphorylase C-terminal WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 SUPERFAMILY SSF50249 40 124 1.61E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 SMART SM00316 37 119 9.9E-12 T 28-03-2018 IPR022967 RNA-binding domain, S1 WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 Pfam PF00575 S1 RNA binding domain 36 118 3.8E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 425 1.5E-171 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 Pfam PF10150 Ribonuclease E/G family 121 391 3.3E-93 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 WM46_RS08725 2625a0ae35edc2b95c9d23404aa89555 1103 Hamap MF_00970 Ribonuclease E [rne]. 1 1089 39.637 T 28-03-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 WM46_RS02015 5116022e925262f6c0dd81ec3849e02c 173 PIRSF PIRSF038321 1 173 1.8E-67 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 WM46_RS02015 5116022e925262f6c0dd81ec3849e02c 173 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 2 168 4.2E-63 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 WM46_RS08160 2150792d4c06187f14a06383a2cc1d99 303 Gene3D G3DSA:3.40.1440.10 28 123 9.3E-17 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS08160 2150792d4c06187f14a06383a2cc1d99 303 SUPERFAMILY SSF82771 42 119 7.59E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS08160 2150792d4c06187f14a06383a2cc1d99 303 SMART SM00465 42 120 2.3E-13 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily WM46_RS22265 dbd287ee2f630b26153acac327e8f571 212 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 149 160 7.7E-6 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS22265 dbd287ee2f630b26153acac327e8f571 212 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 83 100 7.7E-6 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS22265 dbd287ee2f630b26153acac327e8f571 212 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 138 148 7.7E-6 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS22265 dbd287ee2f630b26153acac327e8f571 212 Pfam PF01478 Type IV leader peptidase family 75 170 3.4E-7 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 WM46_RS18450 2085271f5b092f321b70749ae0dbc368 142 Pfam PF05656 Protein of unknown function (DUF805) 8 132 3.3E-21 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 WM46_RS17910 714a4c269a22d9f135a9b290e60eb501 438 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 438 5.1E-201 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS17910 714a4c269a22d9f135a9b290e60eb501 438 PIRSF PIRSF002746 1 438 1.2E-159 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS17910 714a4c269a22d9f135a9b290e60eb501 438 Pfam PF02447 GntP family permease 1 434 3.1E-186 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS11165 3a99b06ac01c963f6fd714169ac20df0 202 ProSitePatterns PS00201 Flavodoxin signature. 32 48 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 WM46_RS11165 3a99b06ac01c963f6fd714169ac20df0 202 TIGRFAM TIGR01752 flav_long: flavodoxin 30 194 1.8E-77 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 WM46_RS11165 3a99b06ac01c963f6fd714169ac20df0 202 PIRSF PIRSF038996 27 198 2.8E-70 T 28-03-2018 IPR010086 Flavodoxin, long chain GO:0010181 WM46_RS11165 3a99b06ac01c963f6fd714169ac20df0 202 Gene3D G3DSA:3.40.50.360 30 196 1.5E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS11165 3a99b06ac01c963f6fd714169ac20df0 202 SUPERFAMILY SSF52218 31 196 2.79E-54 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS11165 3a99b06ac01c963f6fd714169ac20df0 202 Pfam PF00258 Flavodoxin 32 186 5.4E-34 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 PIRSF PIRSF012290 1 219 2.1E-84 T 28-03-2018 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 SUPERFAMILY SSF143414 158 211 1.05E-5 T 28-03-2018 WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 Pfam PF00936 BMC domain 160 208 2.7E-6 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 Pfam PF00936 BMC domain 36 107 2.4E-11 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 TIGRFAM TIGR04502 microcomp_EutL: microcompartment protein EutL 6 217 8.0E-101 T 28-03-2018 IPR030983 Ethanolamine utilization protein EutL GO:0005198 WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 SMART SM00877 146 215 1.0E-5 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS01020 04fd62c1b21b0f1c2059608cd624b98d 219 SMART SM00877 35 132 9.5E-5 T 28-03-2018 IPR000249 Microcompartment protein, bacteria WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 Gene3D G3DSA:1.10.10.10 2 96 2.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 SMART SM00418 16 95 3.2E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 3.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 3.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 3.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 Pfam PF01022 Bacterial regulatory protein, arsR family 23 68 5.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS25695 94cb78b171535e305b4979a25f2e41e0 99 SUPERFAMILY SSF46785 11 98 7.97E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18415 f9fb815c0bacdde716e76bd5f1328c2f 161 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 1 161 47.193 T 28-03-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 WM46_RS18415 f9fb815c0bacdde716e76bd5f1328c2f 161 Gene3D G3DSA:3.50.30.40 1 159 5.3E-36 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein WM46_RS18415 f9fb815c0bacdde716e76bd5f1328c2f 161 SUPERFAMILY SSF89562 2 158 4.06E-44 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein WM46_RS18415 f9fb815c0bacdde716e76bd5f1328c2f 161 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 1 161 3.6E-90 T 28-03-2018 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 WM46_RS18415 f9fb815c0bacdde716e76bd5f1328c2f 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.8E-62 T 28-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 WM46_RS18415 f9fb815c0bacdde716e76bd5f1328c2f 161 Pfam PF03737 Aldolase/RraA 5 152 9.0E-36 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein WM46_RS13920 bfba6ba41a5d7588115a852b86cf205a 151 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 149 37.345 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS13920 bfba6ba41a5d7588115a852b86cf205a 151 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 146 3.5E-60 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS13920 bfba6ba41a5d7588115a852b86cf205a 151 Pfam PF07977 FabA-like domain 17 141 1.9E-40 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 WM46_RS13920 bfba6ba41a5d7588115a852b86cf205a 151 SUPERFAMILY SSF54637 7 146 1.29E-50 T 28-03-2018 IPR029069 HotDog domain WM46_RS13920 bfba6ba41a5d7588115a852b86cf205a 151 Gene3D G3DSA:3.10.129.10 1 149 1.3E-55 T 28-03-2018 WM46_RS25415 49b8451d31ef515eeb5fe223d552bc98 255 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 131 147 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25415 49b8451d31ef515eeb5fe223d552bc98 255 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 48 157 2.7E-23 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25415 49b8451d31ef515eeb5fe223d552bc98 255 Gene3D G3DSA:3.40.50.700 36 178 1.6E-26 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25415 49b8451d31ef515eeb5fe223d552bc98 255 SUPERFAMILY SSF56770 36 168 7.2E-50 T 28-03-2018 WM46_RS09325 77bfaaf294424d42c0b5996cbae89bfb 190 TIGRFAM TIGR01626 ytfJ_HI0045: conserved hypothetical protein YtfJ-family, TIGR01626 1 184 5.7E-67 T 28-03-2018 IPR006513 Conserved hypothetical protein CHP01626, YtfJ WM46_RS09325 77bfaaf294424d42c0b5996cbae89bfb 190 Pfam PF09695 Bacterial protein of unknown function (YtfJ_HI0045) 25 182 9.4E-59 T 28-03-2018 IPR006513 Conserved hypothetical protein CHP01626, YtfJ WM46_RS00080 78d16eae2883edc5bca05b8154a87b14 211 SUPERFAMILY SSF47090 145 207 3.06E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like WM46_RS00080 78d16eae2883edc5bca05b8154a87b14 211 TIGRFAM TIGR03979 His_Ser_Rich: His-Xaa-Ser repeat protein HxsA 4 209 3.8E-48 T 28-03-2018 IPR023928 Conserved hypothetical protein CHP03979 WM46_RS00080 78d16eae2883edc5bca05b8154a87b14 211 Gene3D G3DSA:1.20.141.10 60 209 3.2E-8 T 28-03-2018 WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 Gene3D G3DSA:3.30.70.240 136 199 1.7E-20 T 28-03-2018 WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 3.6E-15 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 SUPERFAMILY SSF54980 136 203 1.64E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 204 6.5E-85 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 Pfam PF01205 Uncharacterized protein family UPF0029 18 125 1.7E-27 T 28-03-2018 IPR001498 Impact, N-terminal WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 SUPERFAMILY SSF54211 3 131 3.11E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 Gene3D G3DSA:3.30.230.30 7 133 5.8E-38 T 28-03-2018 IPR001498 Impact, N-terminal WM46_RS18950 4eec34bd7b9d44d6e42d9686ce42dcb3 204 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 80 109 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site WM46_RS21400 9d8c1b4f5002eeedfce4c718b9685314 406 SUPERFAMILY SSF50129 4 189 2.99E-24 T 28-03-2018 IPR011032 GroES-like WM46_RS21400 9d8c1b4f5002eeedfce4c718b9685314 406 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 102 4.1E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS21400 9d8c1b4f5002eeedfce4c718b9685314 406 Gene3D G3DSA:3.90.180.10 2 187 1.8E-23 T 28-03-2018 WM46_RS21400 9d8c1b4f5002eeedfce4c718b9685314 406 SUPERFAMILY SSF51735 169 330 8.02E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS21400 9d8c1b4f5002eeedfce4c718b9685314 406 Gene3D G3DSA:3.40.50.720 188 310 3.4E-5 T 28-03-2018 WM46_RS21400 9d8c1b4f5002eeedfce4c718b9685314 406 Pfam PF00107 Zinc-binding dehydrogenase 187 325 7.9E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS00140 433900bedf12d541589708c605bc6f3e 158 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 23 148 3.7E-32 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 WM46_RS00140 433900bedf12d541589708c605bc6f3e 158 Gene3D G3DSA:3.30.530.20 14 157 9.6E-33 T 28-03-2018 IPR023393 START-like domain WM46_RS00140 433900bedf12d541589708c605bc6f3e 158 SUPERFAMILY SSF55961 14 155 1.53E-34 T 28-03-2018 WM46_RS15345 88fde459cd9a5ac95ff3b44b56492fef 352 SUPERFAMILY SSF103473 3 344 2.35E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS15345 88fde459cd9a5ac95ff3b44b56492fef 352 Gene3D G3DSA:1.20.1250.20 162 350 1.0E-11 T 28-03-2018 WM46_RS15345 88fde459cd9a5ac95ff3b44b56492fef 352 Gene3D G3DSA:1.20.1250.20 1 156 1.3E-11 T 28-03-2018 WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 Gene3D G3DSA:3.30.300.30 432 536 1.2E-27 T 28-03-2018 WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 Gene3D G3DSA:3.40.50.980 198 349 4.5E-40 T 28-03-2018 WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 Pfam PF00501 AMP-binding enzyme 31 439 8.1E-100 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 193 204 - T 28-03-2018 IPR020845 AMP-binding, conserved site WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 Gene3D G3DSA:2.30.38.10 350 431 1.0E-23 T 28-03-2018 WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 525 1.3E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 Gene3D G3DSA:3.40.50.980 23 197 4.0E-37 T 28-03-2018 WM46_RS07950 1db0faf63602bd6aa99d4a9a1d5d4ae6 546 SUPERFAMILY SSF56801 24 535 9.16E-144 T 28-03-2018 WM46_RS10085 fdd42879e20de0e9e2eb776997f313a5 478 SUPERFAMILY SSF51735 3 294 4.34E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS10085 fdd42879e20de0e9e2eb776997f313a5 478 Gene3D G3DSA:3.30.530.20 325 478 2.6E-5 T 28-03-2018 IPR023393 START-like domain WM46_RS10085 fdd42879e20de0e9e2eb776997f313a5 478 Pfam PF11066 Protein of unknown function (DUF2867) 333 463 3.8E-13 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 WM46_RS10085 fdd42879e20de0e9e2eb776997f313a5 478 Gene3D G3DSA:3.40.50.720 2 302 1.2E-28 T 28-03-2018 WM46_RS10085 fdd42879e20de0e9e2eb776997f313a5 478 Pfam PF13460 NAD(P)H-binding 9 158 5.8E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS10660 e9de184e3b03c7f4ad99209fd89dcb67 49 Hamap MF_01484 Multidrug efflux pump accessory protein AcrZ [acrZ]. 1 46 19.526 T 28-03-2018 IPR019702 Multidrug efflux pump accessory protein AcrZ GO:0005886|GO:0006855|GO:0015238 WM46_RS10660 e9de184e3b03c7f4ad99209fd89dcb67 49 Pfam PF10766 Multidrug efflux pump-associated protein AcrZ 1 48 1.1E-30 T 28-03-2018 IPR019702 Multidrug efflux pump accessory protein AcrZ GO:0005886|GO:0006855|GO:0015238 WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 Gene3D G3DSA:2.40.170.20 180 728 1.5E-82 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 53 728 9.7E-83 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 711 728 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 Gene3D G3DSA:2.170.130.10 43 179 3.9E-36 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 SUPERFAMILY SSF56935 33 728 7.33E-135 T 28-03-2018 WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 42 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 Pfam PF00593 TonB dependent receptor 257 726 6.9E-55 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS05800 cf93d5f936bddf693d0fc731610e7062 728 Pfam PF07715 TonB-dependent Receptor Plug Domain 52 166 1.7E-29 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS15225 956e76d3dc50eb0f6513707526447e8c 380 Pfam PF00529 HlyD membrane-fusion protein of T1SS 36 352 2.0E-10 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS15225 956e76d3dc50eb0f6513707526447e8c 380 SUPERFAMILY SSF111369 192 295 4.71E-13 T 28-03-2018 WM46_RS15225 956e76d3dc50eb0f6513707526447e8c 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 163 302 4.8E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS15225 956e76d3dc50eb0f6513707526447e8c 380 Gene3D G3DSA:1.20.1600.10 47 368 2.1E-25 T 28-03-2018 WM46_RS15225 956e76d3dc50eb0f6513707526447e8c 380 SUPERFAMILY SSF111369 58 139 5.1E-8 T 28-03-2018 WM46_RS03345 6ff52a9f32cd6b3f500c82945e9e77d6 466 Pfam PF07157 DNA circularisation protein N-terminus 25 117 1.8E-31 T 28-03-2018 IPR009826 DNA circulation, N-terminal WM46_RS03345 6ff52a9f32cd6b3f500c82945e9e77d6 466 ProDom PD332323 CIRCULATION DNA PROTEIN TAIL/DNA PHAGE PROPHAGE VIRION FLUMU BACTERIOPHAGE MU-LIKE 20 119 7.0E-34 T 28-03-2018 IPR009826 DNA circulation, N-terminal WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 SUPERFAMILY SSF50331 123 192 2.02E-17 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 Pfam PF03459 TOBE domain 125 187 1.3E-11 T 28-03-2018 IPR005116 Transport-associated OB, type 1 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 Pfam PF03459 TOBE domain 199 258 1.3E-11 T 28-03-2018 IPR005116 Transport-associated OB, type 1 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 Gene3D G3DSA:1.10.10.10 1 107 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 Gene3D G3DSA:2.40.50.100 108 183 2.7E-17 T 28-03-2018 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 16 113 4.1E-40 T 28-03-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 Gene3D G3DSA:2.40.50.100 184 252 2.5E-11 T 28-03-2018 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 SUPERFAMILY SSF46785 2 106 1.54E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 83 3.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 123 192 3.8E-27 T 28-03-2018 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 PIRSF PIRSF005763 1 262 3.3E-98 T 28-03-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 WM46_RS10665 a8a9498672b845c18f77a0b49e7b2140 262 SUPERFAMILY SSF50331 200 259 5.1E-13 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS17825 96b52f6e3c7ab79afecf3983c6fa4135 710 ProDom PD147088 MEMBRANE INNER TRANSMEMBRANE IGAA HOMOLOG DEHYDROGENASE GROWTH ATTENUATOR INTRACELLULAR GENOME 20 697 0.0 T 28-03-2018 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 WM46_RS17825 96b52f6e3c7ab79afecf3983c6fa4135 710 Pfam PF07095 Intracellular growth attenuator protein IgaA 1 704 0.0 T 28-03-2018 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 WM46_RS11335 dc9711fc1b2654050f35a0095a48bac9 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS11335 dc9711fc1b2654050f35a0095a48bac9 241 Pfam PF00005 ABC transporter 17 165 2.6E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS11335 dc9711fc1b2654050f35a0095a48bac9 241 Gene3D G3DSA:3.40.50.300 1 241 7.1E-74 T 28-03-2018 WM46_RS11335 dc9711fc1b2654050f35a0095a48bac9 241 PIRSF PIRSF039085 1 241 5.2E-107 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 WM46_RS11335 dc9711fc1b2654050f35a0095a48bac9 241 SMART SM00382 26 213 1.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11335 dc9711fc1b2654050f35a0095a48bac9 241 SUPERFAMILY SSF52540 1 235 3.3E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS05205 568d71dfb4fe079ca384f1a7e2af3389 84 Pfam PF04226 Transglycosylase associated protein 34 83 3.9E-14 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 WM46_RS08270 6832655a44d36c70e558cdbe5368b76e 287 SUPERFAMILY SSF74650 2 284 2.15E-31 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 WM46_RS08270 6832655a44d36c70e558cdbe5368b76e 287 Pfam PF01263 Aldose 1-epimerase 3 229 1.3E-14 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 WM46_RS08270 6832655a44d36c70e558cdbe5368b76e 287 Gene3D G3DSA:2.70.98.10 2 283 7.5E-34 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 WM46_RS03425 5a001c758aaef42868911d3bfdb73579 288 Pfam PF00288 GHMP kinases N terminal domain 72 120 4.2E-9 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 WM46_RS03425 5a001c758aaef42868911d3bfdb73579 288 SUPERFAMILY SSF54211 3 150 3.87E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold WM46_RS03425 5a001c758aaef42868911d3bfdb73579 288 Gene3D G3DSA:3.30.230.10 21 141 3.5E-15 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup WM46_RS03425 5a001c758aaef42868911d3bfdb73579 288 PIRSF PIRSF033887 1 275 2.4E-68 T 28-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 WM46_RS01080 ead4094f42adfb1e93db1a63cbf4c3f0 291 SUPERFAMILY SSF161098 16 268 5.1E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01080 ead4094f42adfb1e93db1a63cbf4c3f0 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 275 2.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01080 ead4094f42adfb1e93db1a63cbf4c3f0 291 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 19 276 3.7E-112 T 28-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 WM46_RS01080 ead4094f42adfb1e93db1a63cbf4c3f0 291 Gene3D G3DSA:1.10.3720.10 18 282 5.6E-40 T 28-03-2018 WM46_RS01080 ead4094f42adfb1e93db1a63cbf4c3f0 291 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 2 275 7.7E-115 T 28-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 WM46_RS19000 f2b6c30ed04cc7eb62b74eb84eed84a8 89 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 48 8.4E-21 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 WM46_RS19000 f2b6c30ed04cc7eb62b74eb84eed84a8 89 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 82 24.65 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 WM46_RS19000 f2b6c30ed04cc7eb62b74eb84eed84a8 89 Pfam PF02416 mttA/Hcf106 family 4 55 1.9E-15 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 WM46_RS00920 7c91b3a4e913d139b3c3d8fa6fd7ebcd 191 SUPERFAMILY SSF55811 11 187 3.93E-49 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS00920 7c91b3a4e913d139b3c3d8fa6fd7ebcd 191 Pfam PF00293 NUDIX domain 45 163 4.4E-9 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS00920 7c91b3a4e913d139b3c3d8fa6fd7ebcd 191 Gene3D G3DSA:3.90.79.10 1 191 6.3E-36 T 28-03-2018 WM46_RS00920 7c91b3a4e913d139b3c3d8fa6fd7ebcd 191 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 3 185 9.1E-77 T 28-03-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 WM46_RS03740 3767330a3fe99fae67539645f65a944d 305 Pfam PF05661 Protein of unknown function (DUF808) 6 292 1.1E-114 T 28-03-2018 IPR008526 Inner membrane protein YedI WM46_RS03740 3767330a3fe99fae67539645f65a944d 305 PIRSF PIRSF016660 3 305 6.1E-126 T 28-03-2018 IPR008526 Inner membrane protein YedI WM46_RS18225 ea185d510003f2b27fc485976a736be5 405 Gene3D G3DSA:1.20.1250.20 13 208 5.1E-19 T 28-03-2018 WM46_RS18225 ea185d510003f2b27fc485976a736be5 405 SUPERFAMILY SSF103473 17 398 1.27E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS18225 ea185d510003f2b27fc485976a736be5 405 Gene3D G3DSA:1.20.1250.20 209 405 2.6E-17 T 28-03-2018 WM46_RS18225 ea185d510003f2b27fc485976a736be5 405 Pfam PF07690 Major Facilitator Superfamily 26 300 2.5E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS17670 b4255c23c50f85473ef7f0e981edece7 134 Gene3D G3DSA:3.30.300.20 35 134 4.3E-20 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta WM46_RS17670 b4255c23c50f85473ef7f0e981edece7 134 Gene3D G3DSA:2.20.25.10 1 29 7.2E-15 T 28-03-2018 WM46_RS17670 b4255c23c50f85473ef7f0e981edece7 134 SUPERFAMILY SSF82784 1 131 3.14E-43 T 28-03-2018 IPR003718 OsmC/Ohr family WM46_RS17670 b4255c23c50f85473ef7f0e981edece7 134 Pfam PF02566 OsmC-like protein 30 127 9.3E-20 T 28-03-2018 IPR003718 OsmC/Ohr family WM46_RS01710 b3fdaa6085d53927c04b6af74f4ace4a 506 Pfam PF03606 C4-dicarboxylate anaerobic carrier 15 501 4.0E-159 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 WM46_RS18890 e922ddcbc9975a503b845554eac6dffd 207 Gene3D G3DSA:3.40.30.10 17 207 1.3E-35 T 28-03-2018 WM46_RS18890 e922ddcbc9975a503b845554eac6dffd 207 SUPERFAMILY SSF52833 20 205 1.14E-47 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS18890 e922ddcbc9975a503b845554eac6dffd 207 PIRSF PIRSF001488 1 207 5.6E-91 T 28-03-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL WM46_RS18890 e922ddcbc9975a503b845554eac6dffd 207 Pfam PF01323 DSBA-like thioredoxin domain 40 196 9.0E-29 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 WM46_RS18890 e922ddcbc9975a503b845554eac6dffd 207 ProSitePatterns PS00194 Thioredoxin family active site. 41 59 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 SUPERFAMILY SSF54631 66 202 2.53E-32 T 28-03-2018 WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 Pfam PF00571 CBS domain 69 124 6.6E-8 T 28-03-2018 IPR000644 CBS domain WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 Pfam PF00571 CBS domain 141 189 5.9E-5 T 28-03-2018 IPR000644 CBS domain WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 SUPERFAMILY SSF56176 204 289 3.0E-24 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 Pfam PF03471 Transporter associated domain 206 281 6.1E-23 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 Gene3D G3DSA:3.30.465.10 201 285 6.9E-27 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 SMART SM00116 78 127 4.2 T 28-03-2018 IPR000644 CBS domain WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 SMART SM00116 141 189 1.6 T 28-03-2018 IPR000644 CBS domain WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 Gene3D G3DSA:3.10.580.10 50 200 5.8E-35 T 28-03-2018 WM46_RS11310 d3f064d460b10ddc4cd6180589e72791 292 SMART SM01091 205 283 2.1E-31 T 28-03-2018 IPR005170 Transporter-associated domain WM46_RS04680 2e2985760b5ed0bda2940bbf42a517cf 315 SUPERFAMILY SSF56563 134 268 1.57E-6 T 28-03-2018 WM46_RS26155 55b16e5150c01b065e1189235ddcb52d 509 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 113 489 7.0E-84 T 28-03-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain WM46_RS26155 55b16e5150c01b065e1189235ddcb52d 509 SUPERFAMILY SSF52540 80 500 5.34E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26155 55b16e5150c01b065e1189235ddcb52d 509 Gene3D G3DSA:3.40.50.300 74 247 8.4E-13 T 28-03-2018 WM46_RS26155 55b16e5150c01b065e1189235ddcb52d 509 Gene3D G3DSA:3.40.50.300 253 500 4.0E-20 T 28-03-2018 WM46_RS03160 fc84be1327c0339846e4b0f0cd252ec2 72 SUPERFAMILY SSF47413 5 60 4.5E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS03160 fc84be1327c0339846e4b0f0cd252ec2 72 Gene3D G3DSA:1.10.260.40 4 63 3.1E-14 T 28-03-2018 WM46_RS03160 fc84be1327c0339846e4b0f0cd252ec2 72 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 5 62 2.0E-15 T 28-03-2018 IPR031856 Putative bacterial antitoxin YdaS WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 SUPERFAMILY SSF53901 276 399 2.4E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 Gene3D G3DSA:3.40.47.10 276 397 1.3E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 PIRSF PIRSF000429 1 400 7.4E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 400 1.4E-217 T 28-03-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 5.1E-134 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 Gene3D G3DSA:3.40.47.10 1 275 7.4E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 Pfam PF00108 Thiolase, N-terminal domain 5 268 2.7E-71 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 Pfam PF02803 Thiolase, C-terminal domain 276 399 1.4E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 WM46_RS06190 7cb78f0247d999302d404cee70abbf0b 400 SUPERFAMILY SSF53901 1 270 1.03E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS01725 bfc39408498477c04b3ca10f381cc3f6 151 Pfam PF04217 Protein of unknown function, DUF412 11 149 2.7E-58 T 28-03-2018 IPR007334 Uncharacterised protein family UPF0208 WM46_RS01725 bfc39408498477c04b3ca10f381cc3f6 151 Hamap MF_01101 UPF0208 membrane protein YfbV [yfbV]. 9 151 36.885 T 28-03-2018 IPR007334 Uncharacterised protein family UPF0208 WM46_RS10740 8394d6896a73b3ae57420c3fc4957720 350 Pfam PF00793 DAHP synthetase I family 38 338 1.2E-109 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 WM46_RS10740 8394d6896a73b3ae57420c3fc4957720 350 SUPERFAMILY SSF51569 7 348 2.09E-139 T 28-03-2018 WM46_RS10740 8394d6896a73b3ae57420c3fc4957720 350 PIRSF PIRSF001361 1 350 7.2E-165 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM46_RS10740 8394d6896a73b3ae57420c3fc4957720 350 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 4.1E-179 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 WM46_RS10740 8394d6896a73b3ae57420c3fc4957720 350 Gene3D G3DSA:3.20.20.70 8 350 2.1E-134 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS09905 bfcc1d3d9f1c49f20f0e1b551eb87580 208 SUPERFAMILY SSF52499 3 202 5.76E-54 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS09905 bfcc1d3d9f1c49f20f0e1b551eb87580 208 Gene3D G3DSA:3.40.50.850 1 208 1.3E-43 T 28-03-2018 WM46_RS09905 bfcc1d3d9f1c49f20f0e1b551eb87580 208 Pfam PF00857 Isochorismatase family 14 165 2.3E-21 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS07880 ab212590571fcb89ab889f4639eec8b0 370 Pfam PF01594 AI-2E family transporter 15 344 5.6E-60 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like WM46_RS00085 66f39d2655dcda6e9276a57805657442 549 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 26 484 2.1E-23 T 28-03-2018 IPR026487 Sporadically distributed protein CHP04141 WM46_RS23955 859f36895f5eab05fd264c306dcf0723 163 Pfam PF10696 Protein of unknown function (DUF2501) 83 161 5.5E-27 T 28-03-2018 IPR019637 Protein of unknown function DUF2501 WM46_RS02620 27cfb6937296951752ebb9cd7f1455c8 152 Pfam PF06998 Protein of unknown function (DUF1307) 28 149 5.0E-43 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 WM46_RS02620 27cfb6937296951752ebb9cd7f1455c8 152 PIRSF PIRSF006187 1 152 7.8E-61 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 WM46_RS02620 27cfb6937296951752ebb9cd7f1455c8 152 Gene3D G3DSA:3.30.1830.10 28 151 1.2E-39 T 28-03-2018 WM46_RS02620 27cfb6937296951752ebb9cd7f1455c8 152 SUPERFAMILY SSF160704 24 152 1.83E-43 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 WM46_RS18065 ca203eca40fa0a105d04522ec617e0c0 345 Gene3D G3DSA:3.30.360.10 135 338 1.1E-31 T 28-03-2018 WM46_RS18065 ca203eca40fa0a105d04522ec617e0c0 345 SUPERFAMILY SSF51735 3 158 1.17E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS18065 ca203eca40fa0a105d04522ec617e0c0 345 SUPERFAMILY SSF55347 130 268 2.62E-21 T 28-03-2018 WM46_RS18065 ca203eca40fa0a105d04522ec617e0c0 345 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 239 3.9E-16 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS18065 ca203eca40fa0a105d04522ec617e0c0 345 Gene3D G3DSA:3.40.50.720 1 134 1.6E-31 T 28-03-2018 WM46_RS18065 ca203eca40fa0a105d04522ec617e0c0 345 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 120 1.9E-26 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 WM46_RS22210 4e351e9a276144585856063b4b5a985e 94 Gene3D G3DSA:1.20.5.780 10 89 4.0E-23 T 28-03-2018 WM46_RS22210 4e351e9a276144585856063b4b5a985e 94 Pfam PF08681 Protein of unknown function (DUF1778) 13 88 1.1E-19 T 28-03-2018 IPR014795 Vibrio phage ICP1, Orf50 WM46_RS22210 4e351e9a276144585856063b4b5a985e 94 SUPERFAMILY SSF47598 10 87 3.33E-18 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 WM46_RS04870 b006726d83e612ebcdd987bc8c00bb27 165 SMART SM00065 9 161 1.0E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS04870 b006726d83e612ebcdd987bc8c00bb27 165 SUPERFAMILY SSF55781 2 149 2.14E-40 T 28-03-2018 IPR029016 GAF domain-like WM46_RS04870 b006726d83e612ebcdd987bc8c00bb27 165 Pfam PF13185 GAF domain 35 151 2.3E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 WM46_RS04870 b006726d83e612ebcdd987bc8c00bb27 165 Gene3D G3DSA:3.30.450.40 5 155 7.8E-25 T 28-03-2018 IPR029016 GAF domain-like WM46_RS06670 77dee4da8d7f0a4cc78aff7046fdd403 436 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 20 423 3.5E-127 T 28-03-2018 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS06670 77dee4da8d7f0a4cc78aff7046fdd403 436 PIRSF PIRSF002808 2 426 7.6E-38 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS06670 77dee4da8d7f0a4cc78aff7046fdd403 436 SUPERFAMILY SSF103473 5 423 2.88E-76 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS06670 77dee4da8d7f0a4cc78aff7046fdd403 436 Gene3D G3DSA:1.20.1250.20 216 431 5.1E-24 T 28-03-2018 WM46_RS06670 77dee4da8d7f0a4cc78aff7046fdd403 436 Pfam PF07690 Major Facilitator Superfamily 18 305 3.8E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS06670 77dee4da8d7f0a4cc78aff7046fdd403 436 Gene3D G3DSA:1.20.1250.20 5 207 3.0E-37 T 28-03-2018 WM46_RS15090 24522815153318ab181d65eafcf4aca4 96 SUPERFAMILY SSF69786 3 93 1.16E-31 T 28-03-2018 IPR003746 Protein of unknown function DUF167 WM46_RS15090 24522815153318ab181d65eafcf4aca4 96 SMART SM01152 7 83 3.4E-37 T 28-03-2018 IPR003746 Protein of unknown function DUF167 WM46_RS15090 24522815153318ab181d65eafcf4aca4 96 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 93 20.119 T 28-03-2018 IPR003746 Protein of unknown function DUF167 WM46_RS15090 24522815153318ab181d65eafcf4aca4 96 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 10 81 1.5E-25 T 28-03-2018 IPR003746 Protein of unknown function DUF167 WM46_RS15090 24522815153318ab181d65eafcf4aca4 96 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 91 4.1E-33 T 28-03-2018 IPR005228 Conserved hypothetical protein CHP00251 WM46_RS15090 24522815153318ab181d65eafcf4aca4 96 Gene3D G3DSA:3.30.1200.10 1 96 3.6E-31 T 28-03-2018 IPR003746 Protein of unknown function DUF167 WM46_RS21680 00eb938092209c9ad67ad5b48693d552 93 ProDom PD064934 YJCB MEMBRANE INNER ECS5042 21 93 6.0E-34 T 28-03-2018 IPR016958 Uncharacterised conserved protein UCP030798 WM46_RS21680 00eb938092209c9ad67ad5b48693d552 93 Pfam PF15940 Family of unknown function 1 90 5.1E-44 T 28-03-2018 IPR016958 Uncharacterised conserved protein UCP030798 WM46_RS21680 00eb938092209c9ad67ad5b48693d552 93 PIRSF PIRSF030798 1 93 2.3E-56 T 28-03-2018 IPR016958 Uncharacterised conserved protein UCP030798 WM46_RS24605 a9ca4c3ca6967860205e52399a7e3f0d 873 Pfam PF13953 PapC C-terminal domain 794 857 2.5E-23 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS24605 a9ca4c3ca6967860205e52399a7e3f0d 873 SUPERFAMILY SSF141729 41 165 8.89E-38 T 28-03-2018 WM46_RS24605 a9ca4c3ca6967860205e52399a7e3f0d 873 Pfam PF13954 PapC N-terminal domain 43 187 9.4E-51 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS24605 a9ca4c3ca6967860205e52399a7e3f0d 873 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 320 330 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS24605 a9ca4c3ca6967860205e52399a7e3f0d 873 Pfam PF00577 Outer membrane usher protein 203 785 2.9E-221 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS09730 ac7c3ee2d881c3bfa0893942e5e967a4 263 Gene3D G3DSA:1.10.3720.10 7 254 2.2E-30 T 28-03-2018 WM46_RS09730 ac7c3ee2d881c3bfa0893942e5e967a4 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 247 7.7E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS09730 ac7c3ee2d881c3bfa0893942e5e967a4 263 SUPERFAMILY SSF161098 56 237 5.89E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13115 e179ea1ba45b509acfa2356e378531fe 692 Gene3D G3DSA:1.10.3720.10 140 407 1.3E-33 T 28-03-2018 WM46_RS13115 e179ea1ba45b509acfa2356e378531fe 692 Gene3D G3DSA:1.10.3720.10 425 686 4.6E-34 T 28-03-2018 WM46_RS13115 e179ea1ba45b509acfa2356e378531fe 692 SUPERFAMILY SSF161098 434 674 2.34E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13115 e179ea1ba45b509acfa2356e378531fe 692 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 210 403 5.2E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13115 e179ea1ba45b509acfa2356e378531fe 692 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 501 677 9.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13115 e179ea1ba45b509acfa2356e378531fe 692 SUPERFAMILY SSF161098 141 405 3.53E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS07150 13b64dd5ae3dd1be4b6f37e4e7443f31 681 Pfam PF01432 Peptidase family M3 233 678 3.9E-137 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 WM46_RS07150 13b64dd5ae3dd1be4b6f37e4e7443f31 681 Gene3D G3DSA:1.20.1050.40 10 144 3.4E-36 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal WM46_RS07150 13b64dd5ae3dd1be4b6f37e4e7443f31 681 SUPERFAMILY SSF55486 5 679 7.33E-172 T 28-03-2018 WM46_RS07150 13b64dd5ae3dd1be4b6f37e4e7443f31 681 Gene3D G3DSA:1.10.1370.10 146 371 1.3E-40 T 28-03-2018 WM46_RS07150 13b64dd5ae3dd1be4b6f37e4e7443f31 681 Gene3D G3DSA:1.10.1370.10 456 681 1.7E-51 T 28-03-2018 WM46_RS10515 6cf1c5b46518be7da2c96384e9cd39d3 136 Pfam PF11076 Putative inner membrane protein YbhQ 1 132 1.6E-67 T 28-03-2018 IPR021303 Uncharacterised protein family, inner membrane, YbhQ WM46_RS14270 70a5a59bb7d3cabb5764829c5b016faa 457 ProSitePatterns PS00218 Amino acid permeases signature. 44 74 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS14270 70a5a59bb7d3cabb5764829c5b016faa 457 PIRSF PIRSF006060 1 454 3.9E-78 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS14270 70a5a59bb7d3cabb5764829c5b016faa 457 Pfam PF00324 Amino acid permease 19 450 1.6E-127 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS00215 9eba8b6d2f98a2d9a0809a44adb1243e 160 SUPERFAMILY SSF103088 45 157 1.12E-28 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS00215 9eba8b6d2f98a2d9a0809a44adb1243e 160 Gene3D G3DSA:3.30.1330.60 23 160 2.7E-30 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS00215 9eba8b6d2f98a2d9a0809a44adb1243e 160 PRINTS PR01021 OMPA domain signature 56 78 6.9E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS00215 9eba8b6d2f98a2d9a0809a44adb1243e 160 PRINTS PR01021 OMPA domain signature 86 101 6.9E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS00215 9eba8b6d2f98a2d9a0809a44adb1243e 160 PRINTS PR01021 OMPA domain signature 101 117 6.9E-12 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS00215 9eba8b6d2f98a2d9a0809a44adb1243e 160 Pfam PF00691 OmpA family 55 151 3.1E-18 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS09580 5cbec68842f6c06db1495c6bf9f13328 219 ProSitePatterns PS01243 Bax inhibitor-1 family signature. 87 117 - T 28-03-2018 IPR006213 Bax inhibitor 1, conserved site GO:0016021|GO:0043066 WM46_RS09580 5cbec68842f6c06db1495c6bf9f13328 219 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 19 213 7.1E-43 T 28-03-2018 IPR006214 Bax inhibitor 1-related WM46_RS13445 e975e7342184accbf9a377b312cb7a38 318 Gene3D G3DSA:1.10.3470.10 1 318 6.5E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS13445 e975e7342184accbf9a377b312cb7a38 318 Pfam PF01032 FecCD transport family 16 316 6.6E-91 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS13445 e975e7342184accbf9a377b312cb7a38 318 SUPERFAMILY SSF81345 4 316 1.07E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS25335 c8595d8264a58185a250fb50aaf7973f 273 Gene3D G3DSA:3.40.50.300 1 242 7.9E-56 T 28-03-2018 WM46_RS25335 c8595d8264a58185a250fb50aaf7973f 273 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS25335 c8595d8264a58185a250fb50aaf7973f 273 SMART SM00382 31 247 6.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS25335 c8595d8264a58185a250fb50aaf7973f 273 SUPERFAMILY SSF52540 4 232 6.35E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25335 c8595d8264a58185a250fb50aaf7973f 273 Pfam PF00005 ABC transporter 22 169 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS23220 ac6da12e88b0f903a3f4e8e59e572443 214 TIGRFAM TIGR03579 EF_0833: conserved hypothetical protein EF_0833/AHA_3914 5 213 4.2E-119 T 28-03-2018 IPR025456 Protein of unknown function DUF4310 WM46_RS23220 ac6da12e88b0f903a3f4e8e59e572443 214 Pfam PF14187 Domain of unknown function (DUF4310) 4 211 8.5E-108 T 28-03-2018 IPR025456 Protein of unknown function DUF4310 WM46_RS18045 47472b308419216f5b44e7f607871287 446 PIRSF PIRSF002746 1 446 5.7E-154 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS18045 47472b308419216f5b44e7f607871287 446 Pfam PF02447 GntP family permease 5 441 1.7E-165 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS18045 47472b308419216f5b44e7f607871287 446 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 4 444 7.5E-175 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS01105 9744c29e795764882427815c83f95860 431 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 3.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS01105 9744c29e795764882427815c83f95860 431 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 3.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS01105 9744c29e795764882427815c83f95860 431 Pfam PF00155 Aminotransferase class I and II 110 425 9.0E-27 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS01105 9744c29e795764882427815c83f95860 431 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 3.1E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS01105 9744c29e795764882427815c83f95860 431 SUPERFAMILY SSF46785 7 76 7.88E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01105 9744c29e795764882427815c83f95860 431 Gene3D G3DSA:3.40.640.10 103 344 2.1E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS01105 9744c29e795764882427815c83f95860 431 Gene3D G3DSA:1.10.10.10 3 71 6.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01105 9744c29e795764882427815c83f95860 431 SUPERFAMILY SSF53383 84 430 2.13E-63 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS01105 9744c29e795764882427815c83f95860 431 SMART SM00345 10 69 1.4E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS01105 9744c29e795764882427815c83f95860 431 Gene3D G3DSA:3.90.1150.10 345 430 7.2E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS03670 367ff850e37c63670574f8646076154a 438 SUPERFAMILY SSF103473 9 433 3.53E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS03670 367ff850e37c63670574f8646076154a 438 Gene3D G3DSA:1.20.1250.20 13 235 1.4E-21 T 28-03-2018 WM46_RS03670 367ff850e37c63670574f8646076154a 438 Pfam PF00083 Sugar (and other) transporter 28 417 4.8E-20 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS03670 367ff850e37c63670574f8646076154a 438 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS03670 367ff850e37c63670574f8646076154a 438 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 30 425 1.2E-149 T 28-03-2018 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 WM46_RS03670 367ff850e37c63670574f8646076154a 438 Gene3D G3DSA:1.20.1250.20 236 438 1.9E-17 T 28-03-2018 WM46_RS21125 b05d5c30451564bd8a38f254671bfc89 316 PIRSF PIRSF000545 1 316 1.6E-149 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 WM46_RS21125 b05d5c30451564bd8a38f254671bfc89 316 SUPERFAMILY SSF52540 10 316 2.24E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS21125 b05d5c30451564bd8a38f254671bfc89 316 Gene3D G3DSA:3.40.50.300 9 316 1.1E-55 T 28-03-2018 WM46_RS21125 b05d5c30451564bd8a38f254671bfc89 316 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 90 245 3.9E-14 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 WM46_RS21125 b05d5c30451564bd8a38f254671bfc89 316 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 316 1.0E-180 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 WM46_RS21125 b05d5c30451564bd8a38f254671bfc89 316 Hamap MF_00215 Pantothenate kinase [coaA]. 1 316 190.562 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 WM46_RS10820 6210ec66a3423f9915ff4095a185894d 230 TIGRFAM TIGR02796 tolQ: protein TolQ 5 219 1.8E-93 T 28-03-2018 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 WM46_RS10820 6210ec66a3423f9915ff4095a185894d 230 Pfam PF01618 MotA/TolQ/ExbB proton channel family 79 207 5.7E-42 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 WM46_RS10100 49bb1507ae37ec942c510f47c0629fe3 107 Gene3D G3DSA:3.30.110.70 1 105 1.3E-36 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 WM46_RS10100 49bb1507ae37ec942c510f47c0629fe3 107 Pfam PF01906 Putative heavy-metal-binding 1 104 3.7E-40 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 WM46_RS10100 49bb1507ae37ec942c510f47c0629fe3 107 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 24.674 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 WM46_RS10100 49bb1507ae37ec942c510f47c0629fe3 107 SUPERFAMILY SSF117782 1 106 1.27E-37 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 WM46_RS22560 8a9d18a0c77a0e494fdf24e7b81f7c40 40 Pfam PF00817 impB/mucB/samB family 6 34 1.3E-6 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 WM46_RS22560 8a9d18a0c77a0e494fdf24e7b81f7c40 40 SUPERFAMILY SSF56672 1 37 7.83E-10 T 28-03-2018 WM46_RS09555 0df9c0f9813245fa2929c91e511db05f 483 Pfam PF03553 Na+/H+ antiporter family 163 464 1.6E-53 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 WM46_RS09555 0df9c0f9813245fa2929c91e511db05f 483 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 14 469 3.4E-154 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 WM46_RS04420 6c44c604c6ba29b936ac972bbf6d5d4e 90 Pfam PF07825 Excisionase-like protein 5 86 3.7E-22 T 28-03-2018 IPR012884 Excisionase-like GO:0003677|GO:0006310 WM46_RS04420 6c44c604c6ba29b936ac972bbf6d5d4e 90 Gene3D G3DSA:1.10.1660.20 5 82 2.5E-24 T 28-03-2018 WM46_RS04420 6c44c604c6ba29b936ac972bbf6d5d4e 90 SUPERFAMILY SSF46955 4 60 2.2E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain WM46_RS25760 6e3bb6d6478dc5cbfc5a8c4495baef61 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 111 309 1.9E-17 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 WM46_RS25760 6e3bb6d6478dc5cbfc5a8c4495baef61 325 Gene3D G3DSA:3.40.190.10 123 234 1.8E-12 T 28-03-2018 WM46_RS25760 6e3bb6d6478dc5cbfc5a8c4495baef61 325 SUPERFAMILY SSF53850 61 255 7.91E-8 T 28-03-2018 WM46_RS25760 6e3bb6d6478dc5cbfc5a8c4495baef61 325 PIRSF PIRSF017082 2 325 2.0E-76 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 SMART SM00382 33 220 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 Pfam PF00005 ABC transporter 24 172 5.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 SUPERFAMILY SSF52540 4 228 6.1E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 Pfam PF12704 MacB-like periplasmic core domain 272 491 3.2E-41 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 Pfam PF02687 FtsX-like permease family 553 641 1.5E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS10030 aba89eb344fe925f3e3df534dcaeac67 648 Gene3D G3DSA:3.40.50.300 1 261 1.3E-69 T 28-03-2018 WM46_RS25865 c46692b20dd28ede9438fe9dcbeaec48 214 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 100 208 6.2E-16 T 28-03-2018 IPR026337 HEXXH motif domain WM46_RS22665 11fd7b0ad08a016a49c001a2114b9958 517 SUPERFAMILY SSF46785 387 509 1.41E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22665 11fd7b0ad08a016a49c001a2114b9958 517 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 37 236 1.6E-50 T 28-03-2018 IPR022391 Integrating conjugative element relaxase, PFGI-1 class WM46_RS22665 11fd7b0ad08a016a49c001a2114b9958 517 Gene3D G3DSA:2.40.10.200 409 509 1.1E-18 T 28-03-2018 WM46_RS22665 11fd7b0ad08a016a49c001a2114b9958 517 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 392 508 2.8E-16 T 28-03-2018 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal WM46_RS22665 11fd7b0ad08a016a49c001a2114b9958 517 Pfam PF07514 Putative helicase 33 237 8.7E-30 T 28-03-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative WM46_RS22800 68f9b8d503b14d89b1499f2dcb2f8325 131 Pfam PF02300 Fumarate reductase subunit C 3 128 1.2E-56 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 WM46_RS22800 68f9b8d503b14d89b1499f2dcb2f8325 131 Gene3D G3DSA:1.20.1300.10 3 128 1.1E-57 T 28-03-2018 WM46_RS22800 68f9b8d503b14d89b1499f2dcb2f8325 131 SUPERFAMILY SSF81343 2 131 7.2E-59 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS22800 68f9b8d503b14d89b1499f2dcb2f8325 131 PIRSF PIRSF000180 2 130 7.9E-62 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 WM46_RS22800 68f9b8d503b14d89b1499f2dcb2f8325 131 Hamap MF_00708 Fumarate reductase subunit C [frdC]. 2 128 29.98 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 WM46_RS22800 68f9b8d503b14d89b1499f2dcb2f8325 131 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 8 114 2.0E-47 T 28-03-2018 IPR003510 Fumarate reductase, subunit C GO:0016020 WM46_RS06930 21a10d4337694ed840b5becbff5253f9 414 Pfam PF00263 Bacterial type II and III secretion system protein 243 373 4.0E-24 T 28-03-2018 IPR004846 Type II/III secretion system GO:0009306 WM46_RS14715 23acf4914357f2ef601404ea102294e4 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.083 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS14715 23acf4914357f2ef601404ea102294e4 87 Pfam PF01649 Ribosomal protein S20 2 84 5.9E-27 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS14715 23acf4914357f2ef601404ea102294e4 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 87 8.8E-34 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS14715 23acf4914357f2ef601404ea102294e4 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 8.0E-36 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS14715 23acf4914357f2ef601404ea102294e4 87 Gene3D G3DSA:1.20.58.110 1 87 1.0E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS14715 23acf4914357f2ef601404ea102294e4 87 SUPERFAMILY SSF46992 3 86 5.62E-31 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 WM46_RS06710 0e59b0b3d52647acc154d6b41cc6d0ca 189 Gene3D G3DSA:2.30.110.10 1 188 1.1E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS06710 0e59b0b3d52647acc154d6b41cc6d0ca 189 SUPERFAMILY SSF50475 2 186 3.24E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS06710 0e59b0b3d52647acc154d6b41cc6d0ca 189 SMART SM00903 14 158 2.5E-16 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 WM46_RS06710 0e59b0b3d52647acc154d6b41cc6d0ca 189 Pfam PF01613 Flavin reductase like domain 19 154 2.2E-13 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 WM46_RS05440 e1a2fbc0ffafa5918bebf87d81ff1ced 392 SUPERFAMILY SSF103473 7 382 1.96E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS05440 e1a2fbc0ffafa5918bebf87d81ff1ced 392 Gene3D G3DSA:1.20.1250.20 2 193 1.3E-11 T 28-03-2018 WM46_RS05440 e1a2fbc0ffafa5918bebf87d81ff1ced 392 Gene3D G3DSA:1.20.1250.20 195 385 2.7E-14 T 28-03-2018 WM46_RS25145 84beae451793ebe764f115c5f901c4ac 229 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 30 228 1.6E-69 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 WM46_RS25145 84beae451793ebe764f115c5f901c4ac 229 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 6 228 41.049 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 WM46_RS25145 84beae451793ebe764f115c5f901c4ac 229 Gene3D G3DSA:3.20.20.70 1 227 2.2E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS25145 84beae451793ebe764f115c5f901c4ac 229 SUPERFAMILY SSF51366 6 225 1.22E-61 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS01640 eaee2fe571a35f2939cdfab2e634e974 299 Gene3D G3DSA:1.10.10.60 245 295 1.8E-6 T 28-03-2018 WM46_RS01640 eaee2fe571a35f2939cdfab2e634e974 299 Pfam PF04754 Putative transposase, YhgA-like 8 208 3.5E-89 T 28-03-2018 IPR006842 Transposase (putative), YhgA-like WM46_RS01640 eaee2fe571a35f2939cdfab2e634e974 299 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 294 2.4E-58 T 28-03-2018 IPR010106 Recombination-promoting nuclease RpnA WM46_RS00275 24adc3574fe35af326f72c60af267c36 243 Gene3D G3DSA:3.60.140.10 1 243 1.5E-96 T 28-03-2018 WM46_RS00275 24adc3574fe35af326f72c60af267c36 243 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 25 242 3.8E-80 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase WM46_RS00275 24adc3574fe35af326f72c60af267c36 243 SUPERFAMILY SSF64438 4 242 4.76E-90 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic WM46_RS00275 24adc3574fe35af326f72c60af267c36 243 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 241 3.8E-81 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase WM46_RS11835 96dfde99141d44a03c7cf13db7a23ccf 231 Gene3D G3DSA:2.40.10.220 104 224 3.2E-12 T 28-03-2018 WM46_RS11835 96dfde99141d44a03c7cf13db7a23ccf 231 Pfam PF07238 PilZ domain 103 204 6.4E-6 T 28-03-2018 IPR009875 PilZ domain GO:0035438 WM46_RS03845 3ee66204766ce5067aac3c93ef2e04c6 77 SUPERFAMILY SSF64307 2 77 2.75E-24 T 28-03-2018 IPR001455 TusA-like domain WM46_RS03845 3ee66204766ce5067aac3c93ef2e04c6 77 Gene3D G3DSA:3.30.110.40 5 77 6.8E-22 T 28-03-2018 IPR001455 TusA-like domain WM46_RS03845 3ee66204766ce5067aac3c93ef2e04c6 77 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 10 34 - T 28-03-2018 IPR001455 TusA-like domain WM46_RS03845 3ee66204766ce5067aac3c93ef2e04c6 77 Pfam PF01206 Sulfurtransferase TusA 9 77 1.2E-19 T 28-03-2018 IPR001455 TusA-like domain WM46_RS24205 0ee161561b7f65cfe4c57dbad38be2cd 129 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 129 9.5E-60 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 WM46_RS24205 0ee161561b7f65cfe4c57dbad38be2cd 129 SUPERFAMILY SSF51230 4 128 4.91E-46 T 28-03-2018 IPR011053 Single hybrid motif WM46_RS24205 0ee161561b7f65cfe4c57dbad38be2cd 129 Gene3D G3DSA:2.40.50.100 6 129 2.0E-49 T 28-03-2018 WM46_RS24205 0ee161561b7f65cfe4c57dbad38be2cd 129 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 WM46_RS24205 0ee161561b7f65cfe4c57dbad38be2cd 129 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 41.947 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 WM46_RS24205 0ee161561b7f65cfe4c57dbad38be2cd 129 Pfam PF01597 Glycine cleavage H-protein 8 128 5.6E-49 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate WM46_RS26195 363b0f5c9998280fdc1204b085679648 169 Pfam PF07275 Antirestriction protein (ArdA) 9 164 3.7E-32 T 28-03-2018 IPR009899 Antirestriction WM46_RS16605 b79be88ade28a36594a86ee3809d0b17 292 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 36 291 1.5E-92 T 28-03-2018 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 WM46_RS02265 5dca46261f346c4febc4088e05ed02a6 396 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 52 188 1.5E-40 T 28-03-2018 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 WM46_RS02265 5dca46261f346c4febc4088e05ed02a6 396 Gene3D G3DSA:1.20.1250.20 208 396 1.1E-19 T 28-03-2018 WM46_RS02265 5dca46261f346c4febc4088e05ed02a6 396 Pfam PF07690 Major Facilitator Superfamily 16 358 5.4E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS02265 5dca46261f346c4febc4088e05ed02a6 396 SUPERFAMILY SSF103473 8 395 6.28E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS02265 5dca46261f346c4febc4088e05ed02a6 396 Gene3D G3DSA:1.20.1250.20 4 196 2.1E-36 T 28-03-2018 WM46_RS02265 5dca46261f346c4febc4088e05ed02a6 396 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 390 5.9E-156 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 WM46_RS19680 0f631582de937d6c338e29853f44c07e 292 Pfam PF05035 2-keto-3-deoxy-galactonokinase 9 286 1.8E-95 T 28-03-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 Gene3D G3DSA:3.30.499.10 1 152 8.1E-41 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 Gene3D G3DSA:3.30.499.10 303 466 1.7E-52 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 82 95 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 209 222 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 286 300 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 119 132 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 343 354 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 399 412 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 133 148 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 108 116 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 PRINTS PR00415 Aconitase family signature 195 208 1.6E-50 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 62.659 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 Gene3D G3DSA:3.40.1060.10 153 288 2.9E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 2.3E-160 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 5.7E-279 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 WM46_RS14465 a6a45c5a61ad3a70a7634e5b8f026b16 466 SUPERFAMILY SSF53732 2 464 6.67E-167 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 WM46_RS15750 d3fb9c10ed0166de3c2b562e5265fbd2 523 Gene3D G3DSA:1.20.5.1230 142 455 3.3E-4 T 28-03-2018 WM46_RS17260 9b43166021ccfb92c4c47c21301eb798 54 Pfam PF10831 Protein of unknown function (DUF2556) 1 53 9.9E-38 T 28-03-2018 IPR022540 Protein of unknown function DUF2556 WM46_RS17260 9b43166021ccfb92c4c47c21301eb798 54 ProDom PD052549 YHDU TRANSMEMBRANE MEMBRANE PERIPLASMIC 1 54 5.0E-22 T 28-03-2018 IPR022540 Protein of unknown function DUF2556 WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 Gene3D G3DSA:1.10.10.10 4 84 1.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 Gene3D G3DSA:3.40.190.10 180 265 2.5E-9 T 28-03-2018 WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 Pfam PF03466 LysR substrate binding domain 88 290 7.6E-26 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 SUPERFAMILY SSF53850 88 290 3.62E-28 T 28-03-2018 WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 1.2E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 SUPERFAMILY SSF46785 6 88 9.26E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07630 e09b35f656fb96577e1af37e7ba6513d 310 Gene3D G3DSA:3.40.190.10 89 179 8.3E-8 T 28-03-2018 WM46_RS10035 cadb7a6d2808c48be192389b0ee04822 370 Gene3D G3DSA:1.20.1600.10 29 302 2.3E-35 T 28-03-2018 WM46_RS10035 cadb7a6d2808c48be192389b0ee04822 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 293 1.0E-16 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS10035 cadb7a6d2808c48be192389b0ee04822 370 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 361 3.6E-58 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS10035 cadb7a6d2808c48be192389b0ee04822 370 SUPERFAMILY SSF111369 51 297 5.1E-28 T 28-03-2018 WM46_RS10635 329ce0e491297ec95cc6111cec279f0f 331 Gene3D G3DSA:2.130.10.10 2 331 3.2E-56 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 WM46_RS10635 329ce0e491297ec95cc6111cec279f0f 331 Hamap MF_01605 6-phosphogluconolactonase [pgl]. 1 331 56.095 T 28-03-2018 IPR022528 6-phosphogluconolactonase, YbhE-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 WM46_RS10635 329ce0e491297ec95cc6111cec279f0f 331 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 327 1.9E-88 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller WM46_RS10635 329ce0e491297ec95cc6111cec279f0f 331 SUPERFAMILY SSF50974 68 330 1.7E-53 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 WM46_RS23675 cde55a9752da485e797a161249709cce 332 Gene3D G3DSA:1.10.3470.10 11 312 6.3E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS23675 cde55a9752da485e797a161249709cce 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 307 1.8E-47 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS12500 5aee9881e8a7c7c409a0f07782f9ecfd 76 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 6 65 8.4E-24 T 28-03-2018 IPR018691 Protein of unknown function DUF2188 WM46_RS19880 ce9458db557df3bfe08aa9ee4ef15247 397 Hamap MF_01189 Purine ribonucleoside efflux pump NepI [nepI]. 3 394 41.487 T 28-03-2018 IPR023680 Purine ribonucleoside efflux pump, NepI GO:0015211|GO:0015860|GO:0016021 WM46_RS19880 ce9458db557df3bfe08aa9ee4ef15247 397 SUPERFAMILY SSF103473 14 390 7.06E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19880 ce9458db557df3bfe08aa9ee4ef15247 397 Gene3D G3DSA:1.20.1250.20 12 205 3.1E-25 T 28-03-2018 WM46_RS19880 ce9458db557df3bfe08aa9ee4ef15247 397 Gene3D G3DSA:1.20.1250.20 206 393 5.4E-14 T 28-03-2018 WM46_RS19880 ce9458db557df3bfe08aa9ee4ef15247 397 Pfam PF07690 Major Facilitator Superfamily 25 345 3.6E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07065 f5faaa39d4129779291e32bf3cc9d6d2 398 Hamap MF_00517 Probable sugar efflux transporter [sotB]. 1 390 29.868 T 28-03-2018 IPR023495 Sugar efflux transporter, putative WM46_RS07065 f5faaa39d4129779291e32bf3cc9d6d2 398 Gene3D G3DSA:1.20.1250.20 2 198 6.3E-26 T 28-03-2018 WM46_RS07065 f5faaa39d4129779291e32bf3cc9d6d2 398 Gene3D G3DSA:1.20.1250.20 199 398 2.7E-20 T 28-03-2018 WM46_RS07065 f5faaa39d4129779291e32bf3cc9d6d2 398 Pfam PF07690 Major Facilitator Superfamily 18 349 3.8E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07065 f5faaa39d4129779291e32bf3cc9d6d2 398 SUPERFAMILY SSF103473 5 386 4.84E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS24110 696f7064bb0e80630b94083775725a90 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS24110 696f7064bb0e80630b94083775725a90 239 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 52.051 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 WM46_RS24110 696f7064bb0e80630b94083775725a90 239 Pfam PF01048 Phosphorylase superfamily 15 218 7.6E-40 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS24110 696f7064bb0e80630b94083775725a90 239 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 234 5.4E-126 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 WM46_RS24110 696f7064bb0e80630b94083775725a90 239 Gene3D G3DSA:3.40.50.1580 9 235 7.8E-57 T 28-03-2018 WM46_RS24110 696f7064bb0e80630b94083775725a90 239 SUPERFAMILY SSF53167 3 234 2.75E-93 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS08905 9a49156bb254cedd28a3ede6e29d40b3 75 Pfam PF07119 Protein of unknown function (DUF1375) 48 68 2.5E-5 T 28-03-2018 IPR010780 Protein of unknown function DUF1375 WM46_RS08905 9a49156bb254cedd28a3ede6e29d40b3 75 Pfam PF07119 Protein of unknown function (DUF1375) 9 42 3.4E-4 T 28-03-2018 IPR010780 Protein of unknown function DUF1375 WM46_RS12405 27339633e7fc47d02b324fce00aaab8c 125 PIRSF PIRSF016789 2 123 1.8E-48 T 28-03-2018 IPR007401 Protein of unknown function DUF454 WM46_RS12405 27339633e7fc47d02b324fce00aaab8c 125 Pfam PF04304 Protein of unknown function (DUF454) 3 116 2.9E-40 T 28-03-2018 IPR007401 Protein of unknown function DUF454 WM46_RS13260 28ab729294f067d5d5ffaff2b08e7ced 253 SUPERFAMILY SSF52540 4 226 1.74E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS13260 28ab729294f067d5d5ffaff2b08e7ced 253 SMART SM00382 29 213 2.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS13260 28ab729294f067d5d5ffaff2b08e7ced 253 Gene3D G3DSA:3.40.50.300 3 249 1.6E-56 T 28-03-2018 WM46_RS13260 28ab729294f067d5d5ffaff2b08e7ced 253 Pfam PF00005 ABC transporter 20 169 3.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 2.9E-136 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 349 50.386 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 SUPERFAMILY SSF51726 1 353 1.44E-120 T 28-03-2018 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 Gene3D G3DSA:3.20.20.210 1 354 2.4E-109 T 28-03-2018 WM46_RS21255 006641c4b8bdf363f6eaf26f32d5e80d 354 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 347 6.4E-141 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 SUPERFAMILY SSF51445 3 471 9.11E-161 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 Gene3D G3DSA:3.20.20.80 1 474 3.0E-156 T 28-03-2018 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 6.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 410 427 6.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 6.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 389 400 6.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 6.7E-16 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS25435 0e4d6f77e45fd923076e5648d0515078 474 Pfam PF00232 Glycosyl hydrolase family 1 3 470 1.6E-135 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Pfam PF01493 GXGXG motif 1267 1450 1.8E-74 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Gene3D G3DSA:3.20.20.70 810 1239 5.1E-146 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 SUPERFAMILY SSF51395 465 1222 5.04E-251 T 28-03-2018 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Gene3D G3DSA:2.160.20.60 1242 1516 6.4E-96 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Gene3D G3DSA:3.20.20.70 469 809 7.4E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 SUPERFAMILY SSF69336 1242 1496 1.83E-87 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Pfam PF00310 Glutamine amidotransferases class-II 43 456 1.1E-175 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Pfam PF04898 Glutamate synthase central domain 488 768 1.2E-104 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Gene3D G3DSA:3.60.20.10 43 468 2.2E-143 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 Pfam PF01645 Conserved region in glutamate synthase 824 1187 2.1E-158 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 WM46_RS16985 e4a4791a7d4613fab7346ff59867b184 1517 SUPERFAMILY SSF56235 43 460 4.03E-149 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal WM46_RS11495 6133fdcdf3c2a4239f729861c4a77db1 183 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 13 175 2.3E-57 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 WM46_RS11495 6133fdcdf3c2a4239f729861c4a77db1 183 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 13 175 4.8E-52 T 28-03-2018 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 WM46_RS07985 1a4adf175621ba9c3190bbbe6e3624ac 154 SUPERFAMILY SSF54001 34 154 1.08E-39 T 28-03-2018 WM46_RS07985 1a4adf175621ba9c3190bbbe6e3624ac 154 Gene3D G3DSA:3.90.1720.10 35 154 9.1E-36 T 28-03-2018 WM46_RS07985 1a4adf175621ba9c3190bbbe6e3624ac 154 Pfam PF00877 NlpC/P60 family 47 153 7.7E-30 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain WM46_RS20605 93104baaae4d314d61f3cc850ec2cb6b 339 SUPERFAMILY SSF161098 89 160 1.96E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20605 93104baaae4d314d61f3cc850ec2cb6b 339 SUPERFAMILY SSF161098 200 322 1.96E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20605 93104baaae4d314d61f3cc850ec2cb6b 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 336 1.3E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20605 93104baaae4d314d61f3cc850ec2cb6b 339 Gene3D G3DSA:1.10.3720.10 3 325 9.0E-47 T 28-03-2018 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 Pfam PF13396 Phospholipase_D-nuclease N-terminal 22 59 1.1E-6 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 Gene3D G3DSA:3.30.870.10 316 476 1.0E-26 T 28-03-2018 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 Pfam PF13091 PLD-like domain 331 440 2.2E-22 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 Pfam PF13091 PLD-like domain 134 244 5.8E-11 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 SMART SM00155 399 426 8.2E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 SMART SM00155 219 246 1.4E-4 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 Hamap MF_00190 Cardiolipin synthase A [clsA]. 2 486 51.688 T 28-03-2018 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 Gene3D G3DSA:3.30.870.10 99 288 8.4E-27 T 28-03-2018 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 SUPERFAMILY SSF56024 274 473 5.38E-47 T 28-03-2018 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 SUPERFAMILY SSF56024 66 315 1.7E-45 T 28-03-2018 WM46_RS05780 fea6a92e068760d98765d1f509c46b72 486 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 6 486 1.1E-220 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 SUPERFAMILY SSF46689 218 265 1.39E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 Gene3D G3DSA:1.10.10.60 161 221 2.2E-10 T 28-03-2018 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 SUPERFAMILY SSF51215 18 148 1.05E-13 T 28-03-2018 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 Pfam PF02311 AraC-like ligand binding domain 25 144 1.1E-17 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 Pfam PF12833 Helix-turn-helix domain 187 264 3.7E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 Gene3D G3DSA:1.10.10.60 222 266 1.4E-11 T 28-03-2018 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 SMART SM00342 181 263 3.7E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 Gene3D G3DSA:2.60.120.280 7 160 1.4E-8 T 28-03-2018 WM46_RS04000 286bbdd14667b1cb2567df8176759a3f 268 SUPERFAMILY SSF46689 165 215 6.87E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS15500 bb5053ca3f11ae8283b4c998dcef838a 506 Pfam PF07916 TraG-like protein, N-terminal region 8 485 3.6E-102 T 28-03-2018 IPR012931 TraG-like, N-terminal WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 Gene3D G3DSA:3.40.47.10 240 389 4.0E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 236 337 1.6E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 SUPERFAMILY SSF53901 2 230 6.86E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 147 163 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 SMART SM00825 Beta-ketoacyl synthase 45 388 1.2E-10 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 Gene3D G3DSA:3.40.47.10 1 234 1.3E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 81 229 5.5E-24 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM46_RS18305 e9420c2d8beb9454a5e5db2cd9a8b197 389 SUPERFAMILY SSF53901 203 387 1.27E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 WM46_RS02900 bfe51f9f8365d156c29eedf5e40b644e 297 SUPERFAMILY SSF53448 2 283 4.28E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02900 bfe51f9f8365d156c29eedf5e40b644e 297 Pfam PF00483 Nucleotidyl transferase 5 273 1.5E-21 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 WM46_RS02900 bfe51f9f8365d156c29eedf5e40b644e 297 Gene3D G3DSA:3.90.550.10 1 297 8.9E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02900 bfe51f9f8365d156c29eedf5e40b644e 297 TIGRFAM TIGR01105 galF: regulatory protein GalF 1 297 1.4E-205 T 28-03-2018 IPR005774 UTP-glucose pyrophosphorylase, regulatory subunit GO:0006011|GO:0030234 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 WM46_RS16800 d2433c81b53dbd7904408f69a7f1c5b3 110 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 7.8E-44 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM46_RS16800 d2433c81b53dbd7904408f69a7f1c5b3 110 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 7.8E-44 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM46_RS16800 d2433c81b53dbd7904408f69a7f1c5b3 110 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 7.8E-44 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM46_RS16800 d2433c81b53dbd7904408f69a7f1c5b3 110 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 7.8E-44 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM46_RS16800 d2433c81b53dbd7904408f69a7f1c5b3 110 Pfam PF03840 Preprotein translocase SecG subunit 5 72 4.1E-22 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM46_RS16800 d2433c81b53dbd7904408f69a7f1c5b3 110 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 74 2.8E-27 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 WM46_RS06415 25d868739aeff484e6126169bcf4721b 447 SMART SM01150 11 401 1.0E-223 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 WM46_RS06415 25d868739aeff484e6126169bcf4721b 447 Pfam PF07063 Domain of unknown function (DUF1338) 9 401 2.9E-118 T 28-03-2018 IPR009770 Domain of unknown function DUF1338 WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 Pfam PF01842 ACT domain 119 188 3.4E-7 T 28-03-2018 IPR002912 ACT domain WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 Pfam PF13740 ACT domain 29 104 5.1E-25 T 28-03-2018 WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 Gene3D G3DSA:3.30.70.260 115 202 4.0E-14 T 28-03-2018 WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 Gene3D G3DSA:3.30.70.260 29 111 3.4E-11 T 28-03-2018 WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 PIRSF PIRSF028103 27 202 3.5E-68 T 28-03-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 SUPERFAMILY SSF55021 113 201 2.79E-17 T 28-03-2018 WM46_RS00845 eaf093cfa70525ef638806a7ce8d3530 212 SUPERFAMILY SSF55021 28 110 1.6E-16 T 28-03-2018 WM46_RS18270 1a2eaa2962f92feee823462a3828ca3e 453 Gene3D G3DSA:3.30.300.30 343 453 1.3E-13 T 28-03-2018 WM46_RS18270 1a2eaa2962f92feee823462a3828ca3e 453 Gene3D G3DSA:3.40.50.980 86 140 0.01 T 28-03-2018 WM46_RS18270 1a2eaa2962f92feee823462a3828ca3e 453 Pfam PF00501 AMP-binding enzyme 130 285 3.0E-8 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 WM46_RS18270 1a2eaa2962f92feee823462a3828ca3e 453 Gene3D G3DSA:3.40.50.980 141 294 7.0E-17 T 28-03-2018 WM46_RS18270 1a2eaa2962f92feee823462a3828ca3e 453 SUPERFAMILY SSF56801 15 451 3.14E-52 T 28-03-2018 WM46_RS18270 1a2eaa2962f92feee823462a3828ca3e 453 Gene3D G3DSA:3.40.50.980 4 84 1.4E-7 T 28-03-2018 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 PRINTS PR00481 Cytosol aminopeptidase signature 287 308 6.0E-54 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 PRINTS PR00481 Cytosol aminopeptidase signature 374 389 6.0E-54 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 PRINTS PR00481 Cytosol aminopeptidase signature 324 345 6.0E-54 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 PRINTS PR00481 Cytosol aminopeptidase signature 346 366 6.0E-54 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 PRINTS PR00481 Cytosol aminopeptidase signature 265 282 6.0E-54 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 Gene3D G3DSA:3.40.220.10 1 157 6.2E-31 T 28-03-2018 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 Gene3D G3DSA:3.40.630.10 170 500 4.5E-134 T 28-03-2018 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 SUPERFAMILY SSF53187 180 496 1.51E-124 T 28-03-2018 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 5.3E-34 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 SUPERFAMILY SSF52949 1 184 7.65E-52 T 28-03-2018 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 498 41.417 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 489 2.8E-123 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS23415 6d1981e73178f8b5873bd797f5044cf4 503 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 350 357 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 WM46_RS14220 7228137c3cb837b29ed0a79af51e5f62 317 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 14 314 3.0E-102 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS14220 7228137c3cb837b29ed0a79af51e5f62 317 Hamap MF_00070 2-keto-3-deoxygluconate permease [kdgT]. 1 312 32.422 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS14220 7228137c3cb837b29ed0a79af51e5f62 317 Pfam PF03812 2-keto-3-deoxygluconate permease 3 306 2.9E-123 T 28-03-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 WM46_RS19740 6565a97a8922ae90174512c3a2f0bb7d 449 Gene3D G3DSA:1.20.1250.20 217 445 3.1E-13 T 28-03-2018 WM46_RS19740 6565a97a8922ae90174512c3a2f0bb7d 449 SUPERFAMILY SSF103473 13 434 1.44E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS19740 6565a97a8922ae90174512c3a2f0bb7d 449 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 446 1.1E-138 T 28-03-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 WM46_RS19740 6565a97a8922ae90174512c3a2f0bb7d 449 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 62 87 - T 28-03-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 WM46_RS19740 6565a97a8922ae90174512c3a2f0bb7d 449 Gene3D G3DSA:1.20.1250.20 11 210 3.5E-15 T 28-03-2018 WM46_RS19740 6565a97a8922ae90174512c3a2f0bb7d 449 Pfam PF13347 MFS/sugar transport protein 13 434 9.1E-103 T 28-03-2018 WM46_RS22885 49c45384638a3cb2b1cb9ef3a11f27b9 102 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.396 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 WM46_RS22885 49c45384638a3cb2b1cb9ef3a11f27b9 102 Gene3D G3DSA:2.30.30.100 4 73 1.1E-33 T 28-03-2018 WM46_RS22885 49c45384638a3cb2b1cb9ef3a11f27b9 102 SUPERFAMILY SSF50182 7 69 4.04E-24 T 28-03-2018 IPR010920 LSM domain WM46_RS22885 49c45384638a3cb2b1cb9ef3a11f27b9 102 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 2.0E-29 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 WM46_RS22885 49c45384638a3cb2b1cb9ef3a11f27b9 102 Pfam PF17209 Hfq protein 7 69 4.9E-31 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 SUPERFAMILY SSF51445 7 405 6.69E-89 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 SUPERFAMILY SSF51011 405 491 9.26E-28 T 28-03-2018 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 PIRSF PIRSF001021 1 494 9.2E-208 T 28-03-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 415 491 6.8E-7 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 Gene3D G3DSA:3.20.20.80 4 397 1.5E-69 T 28-03-2018 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 Pfam PF00128 Alpha amylase, catalytic domain 21 367 8.9E-23 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 Gene3D G3DSA:2.60.40.1180 407 495 4.7E-30 T 28-03-2018 WM46_RS03860 c5de0859f16ef90c768f0f96ebe69a86 495 SMART SM00642 4 402 3.4E-61 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 WM46_RS09340 a7562cae35ae3341dd3fb301438a5ec5 390 Gene3D G3DSA:3.40.640.10 61 277 8.6E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS09340 a7562cae35ae3341dd3fb301438a5ec5 390 SUPERFAMILY SSF53383 9 388 4.65E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS09340 a7562cae35ae3341dd3fb301438a5ec5 390 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 WM46_RS09340 a7562cae35ae3341dd3fb301438a5ec5 390 Gene3D G3DSA:3.90.1150.10 278 390 1.3E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS09340 a7562cae35ae3341dd3fb301438a5ec5 390 Pfam PF00155 Aminotransferase class I and II 45 384 7.4E-51 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 Pfam PF07719 Tetratricopeptide repeat 329 360 2.1E-5 T 28-03-2018 IPR013105 Tetratricopeptide repeat 2 WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 SUPERFAMILY SSF48452 300 383 4.92E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 SUPERFAMILY SSF48452 95 226 4.92E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 Pfam PF07219 HemY protein N-terminus 26 132 6.4E-36 T 28-03-2018 IPR010817 HemY, N-terminal WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 Gene3D G3DSA:1.25.40.10 224 390 7.5E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 Gene3D G3DSA:1.25.40.10 77 223 6.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS19155 42445d61b67c4e288474a48baee802e0 398 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 4 386 3.1E-119 T 28-03-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 WM46_RS00030 d93faf6b5fc766f9dc0a6f68c61342ce 128 Gene3D G3DSA:3.30.1450.10 25 121 9.7E-6 T 28-03-2018 WM46_RS05830 6f406cf6c8965a3c1f1f24a73a9252ad 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 38.865 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05830 6f406cf6c8965a3c1f1f24a73a9252ad 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05830 6f406cf6c8965a3c1f1f24a73a9252ad 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 2.2E-110 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05830 6f406cf6c8965a3c1f1f24a73a9252ad 268 Gene3D G3DSA:3.20.20.70 2 268 3.6E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS05830 6f406cf6c8965a3c1f1f24a73a9252ad 268 Pfam PF00290 Tryptophan synthase alpha chain 8 266 2.4E-100 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 WM46_RS05830 6f406cf6c8965a3c1f1f24a73a9252ad 268 SUPERFAMILY SSF51366 1 266 3.3E-91 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 Gene3D G3DSA:3.90.79.10 1 138 5.1E-28 T 28-03-2018 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 SUPERFAMILY SSF55811 2 125 5.28E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 Hamap MF_01846 Nucleoside triphosphatase NudI [nudI]. 1 141 45.762 T 28-03-2018 IPR023781 Nucleoside triphosphatase NudI GO:0016818 KEGG: 00240+3.6.1.23+3.6.1.12 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 WM46_RS01920 acd356712aa3e714b3fd6bc0543db569 141 Pfam PF00293 NUDIX domain 2 128 2.1E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 WM46_RS08960 51e19c6f3870409cee796375d896a40e 129 Pfam PF10627 Curli assembly protein CsgE 27 128 5.6E-34 T 28-03-2018 IPR018900 Curli assembly protein CsgE WM46_RS22345 4a919445bfa84f520cf5f5c15b190258 150 SUPERFAMILY SSF51161 10 148 8.32E-30 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS22345 4a919445bfa84f520cf5f5c15b190258 150 Gene3D G3DSA:2.160.10.10 8 150 4.8E-31 T 28-03-2018 WM46_RS22345 4a919445bfa84f520cf5f5c15b190258 150 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 29 60 8.7E-6 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS10760 257b285325b8868d416630085f5507df 239 Pfam PF04973 Nicotinamide mononucleotide transporter 23 226 6.2E-51 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 WM46_RS10760 257b285325b8868d416630085f5507df 239 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 22 231 2.6E-72 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 WM46_RS06150 963f11399dc3c84d73cb4de7af1453d2 86 Pfam PF10749 Protein of unknown function (DUF2534) 4 82 5.2E-40 T 28-03-2018 IPR019685 Protein of unknown function DUF2534 WM46_RS23670 4605d993081cd898001d1e457d092053 340 Gene3D G3DSA:3.40.50.2300 144 340 1.9E-22 T 28-03-2018 WM46_RS23670 4605d993081cd898001d1e457d092053 340 SUPERFAMILY SSF53822 28 340 2.36E-84 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS23670 4605d993081cd898001d1e457d092053 340 Pfam PF13407 Periplasmic binding protein domain 30 285 3.1E-53 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS23670 4605d993081cd898001d1e457d092053 340 Gene3D G3DSA:3.40.50.2300 16 143 2.6E-15 T 28-03-2018 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 PRINTS PR01035 Tetracycline resistance protein signature 142 164 2.3E-12 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 PRINTS PR01035 Tetracycline resistance protein signature 112 133 2.3E-12 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 PRINTS PR01035 Tetracycline resistance protein signature 23 39 2.3E-12 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 PRINTS PR01035 Tetracycline resistance protein signature 85 109 2.3E-12 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 PRINTS PR01035 Tetracycline resistance protein signature 311 331 2.3E-12 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 PRINTS PR01035 Tetracycline resistance protein signature 346 369 2.3E-12 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 SUPERFAMILY SSF103473 215 398 3.4E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 Gene3D G3DSA:1.20.1250.20 203 404 2.6E-29 T 28-03-2018 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 SUPERFAMILY SSF103473 9 201 9.02E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 Pfam PF07690 Major Facilitator Superfamily 18 261 6.6E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 Gene3D G3DSA:1.20.1250.20 9 202 6.1E-39 T 28-03-2018 WM46_RS08895 ec6054f978fca01740fb29e50f21ac42 406 Hamap MF_01528 Multidrug resistance protein MdtG [mdtG]. 1 404 51.529 T 28-03-2018 IPR023692 Multidrug resistance protein MdtG GO:0005215|GO:0005886 WM46_RS20250 f9ccf62e83feaa0e1fc113a5a7aa576c 344 Gene3D G3DSA:3.90.550.10 3 278 2.2E-48 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS20250 f9ccf62e83feaa0e1fc113a5a7aa576c 344 Pfam PF00535 Glycosyl transferase family 2 9 137 4.9E-32 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS20250 f9ccf62e83feaa0e1fc113a5a7aa576c 344 SUPERFAMILY SSF53448 8 225 2.25E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS12815 78d611ce98786430dc4973197f267f78 110 Pfam PF02699 Preprotein translocase subunit 22 99 3.4E-26 T 28-03-2018 IPR003849 Preprotein translocase YajC WM46_RS12815 78d611ce98786430dc4973197f267f78 110 SMART SM01323 19 102 9.7E-37 T 28-03-2018 IPR003849 Preprotein translocase YajC WM46_RS12815 78d611ce98786430dc4973197f267f78 110 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 19 102 8.2E-34 T 28-03-2018 IPR003849 Preprotein translocase YajC WM46_RS12815 78d611ce98786430dc4973197f267f78 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 3.1E-17 T 28-03-2018 IPR003849 Preprotein translocase YajC WM46_RS12815 78d611ce98786430dc4973197f267f78 110 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 3.1E-17 T 28-03-2018 IPR003849 Preprotein translocase YajC WM46_RS16390 0a2f01337f635a17904326c91067096e 184 PIRSF PIRSF011443 1 180 3.5E-73 T 28-03-2018 IPR026267 Inner membrane protein YgjV WM46_RS16390 0a2f01337f635a17904326c91067096e 184 Pfam PF10688 Bacterial inner membrane protein 5 163 2.6E-57 T 28-03-2018 IPR019629 Uncharacterised protein family HI1736/YgjV WM46_RS22745 f15e05a5e43274728c7697b523046b63 117 Pfam PF13698 Domain of unknown function (DUF4156) 23 115 2.0E-31 T 28-03-2018 IPR025294 Protein of unknown function DUF4156 WM46_RS25375 31daed10ef05e3c48a0511166db390a6 290 PIRSF PIRSF005624 70 290 1.6E-94 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 WM46_RS25375 31daed10ef05e3c48a0511166db390a6 290 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 76 289 1.3E-98 T 28-03-2018 IPR004392 Hydrogenase accessory protein HypB GO:0006461|GO:0016151 WM46_RS25375 31daed10ef05e3c48a0511166db390a6 290 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 106 267 1.1E-34 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain WM46_RS25375 31daed10ef05e3c48a0511166db390a6 290 Gene3D G3DSA:3.40.50.300 104 261 8.5E-21 T 28-03-2018 WM46_RS25375 31daed10ef05e3c48a0511166db390a6 290 SUPERFAMILY SSF52540 88 286 2.97E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS25100 bceef3ec13949aee8694ae340a6ea8c4 380 Gene3D G3DSA:3.90.1510.10 42 269 3.3E-96 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 WM46_RS25100 bceef3ec13949aee8694ae340a6ea8c4 380 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 3.2E-162 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS25100 bceef3ec13949aee8694ae340a6ea8c4 380 SUPERFAMILY SSF110738 1 375 6.28E-141 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS25100 bceef3ec13949aee8694ae340a6ea8c4 380 Gene3D G3DSA:3.20.20.70 270 377 0.12 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS25100 bceef3ec13949aee8694ae340a6ea8c4 380 Pfam PF02595 Glycerate kinase family 3 373 1.8E-148 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS25100 bceef3ec13949aee8694ae340a6ea8c4 380 PIRSF PIRSF006078 1 378 1.7E-137 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 WM46_RS04485 b93198d1bb29fc8c507e897c21feeb64 304 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 32 205 2.4E-21 T 28-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 WM46_RS04485 b93198d1bb29fc8c507e897c21feeb64 304 Pfam PF03837 RecT family 34 212 1.9E-32 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 WM46_RS18070 9dab1290cacf3033eef23be941b2d138 162 SUPERFAMILY SSF55729 4 161 1.31E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS18070 9dab1290cacf3033eef23be941b2d138 162 Gene3D G3DSA:3.40.630.30 1 162 2.2E-35 T 28-03-2018 WM46_RS18070 9dab1290cacf3033eef23be941b2d138 162 Pfam PF00583 Acetyltransferase (GNAT) family 34 136 1.2E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS05135 fc354082d27c797ae2c3f0336183a5c0 97 Pfam PF05166 YcgL domain 3 75 1.0E-31 T 28-03-2018 IPR027354 YcgL domain WM46_RS05135 fc354082d27c797ae2c3f0336183a5c0 97 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 1 82 9.0E-40 T 28-03-2018 IPR027354 YcgL domain WM46_RS05135 fc354082d27c797ae2c3f0336183a5c0 97 Hamap MF_01866 Protein YcgL [ycgL]. 1 88 26.813 T 28-03-2018 IPR027354 YcgL domain WM46_RS05135 fc354082d27c797ae2c3f0336183a5c0 97 SUPERFAMILY SSF160191 1 94 7.85E-40 T 28-03-2018 WM46_RS07145 defaa15596a9fbd0cdcb9a584b80434b 388 Gene3D G3DSA:3.40.710.10 35 376 1.6E-60 T 28-03-2018 WM46_RS07145 defaa15596a9fbd0cdcb9a584b80434b 388 SUPERFAMILY SSF56601 43 378 4.73E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like WM46_RS07145 defaa15596a9fbd0cdcb9a584b80434b 388 Pfam PF00144 Beta-lactamase 46 373 1.6E-49 T 28-03-2018 IPR001466 Beta-lactamase-related WM46_RS15235 93f76864143c0910424fb292539d94ce 137 Gene3D G3DSA:1.20.1600.10 3 118 1.2E-16 T 28-03-2018 WM46_RS15235 93f76864143c0910424fb292539d94ce 137 SUPERFAMILY SSF56954 14 116 2.62E-18 T 28-03-2018 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 SMART SM00342 173 255 1.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 Gene3D G3DSA:1.10.10.60 211 258 5.5E-6 T 28-03-2018 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 251 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 SUPERFAMILY SSF51182 10 177 1.56E-12 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 Pfam PF12833 Helix-turn-helix domain 179 256 2.7E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 Gene3D G3DSA:1.10.10.60 155 210 6.5E-9 T 28-03-2018 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 Gene3D G3DSA:2.60.120.10 8 106 3.3E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 Pfam PF02311 AraC-like ligand binding domain 24 94 8.7E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS15350 f45db0df6bea4e4ecbcd80bfe8654ee9 259 SUPERFAMILY SSF46689 209 257 5.82E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS13010 6d5d8cb5501d22e7202dc21c08fb5dbb 68 ProDom PD073772 MEMBRANE TRANSMEMBRANE YAIZ INNER ECS0430 GENOME 1 65 6.0E-29 T 28-03-2018 IPR020490 Uncharacterised protein family YaiZ WM46_RS13010 6d5d8cb5501d22e7202dc21c08fb5dbb 68 Pfam PF10953 Protein of unknown function (DUF2754) 1 66 9.9E-43 T 28-03-2018 IPR020490 Uncharacterised protein family YaiZ WM46_RS12880 f6c9820eb6fb7120b0edd27c70890eb6 181 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 75 7.1E-9 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain WM46_RS12880 f6c9820eb6fb7120b0edd27c70890eb6 181 Gene3D G3DSA:3.30.70.100 1 100 4.7E-14 T 28-03-2018 WM46_RS12880 f6c9820eb6fb7120b0edd27c70890eb6 181 SUPERFAMILY SSF54909 3 97 3.83E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 SUPERFAMILY SSF103088 59 171 2.88E-34 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 70 172 2.1E-46 T 28-03-2018 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 ProSitePatterns PS01068 OmpA-like domain. 104 148 - T 28-03-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 Gene3D G3DSA:3.30.1330.60 43 172 3.5E-34 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 PRINTS PR01021 OMPA domain signature 117 133 8.3E-17 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 PRINTS PR01021 OMPA domain signature 102 117 8.3E-17 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 PRINTS PR01021 OMPA domain signature 72 94 8.3E-17 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 WM46_RS10800 a76fe20fd4ad4bb7b07df2057732e2ac 172 Pfam PF00691 OmpA family 71 166 1.3E-21 T 28-03-2018 IPR006665 OmpA-like domain WM46_RS07450 683a3e37504bfda91e1aeba23d5df27f 352 Pfam PF03116 NQR2, RnfD, RnfE family 6 348 5.5E-107 T 28-03-2018 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 WM46_RS07450 683a3e37504bfda91e1aeba23d5df27f 352 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 349 4.3E-147 T 28-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 WM46_RS07450 683a3e37504bfda91e1aeba23d5df27f 352 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 350 28.87 T 28-03-2018 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 WM46_RS22105 a900c4ad82b5bc4f81edd7b2dd813038 383 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 377 3.0E-43 T 28-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 WM46_RS22105 a900c4ad82b5bc4f81edd7b2dd813038 383 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 265 1.6E-17 T 28-03-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain WM46_RS22105 a900c4ad82b5bc4f81edd7b2dd813038 383 Gene3D G3DSA:1.20.1600.10 18 371 2.0E-33 T 28-03-2018 WM46_RS22105 a900c4ad82b5bc4f81edd7b2dd813038 383 SUPERFAMILY SSF111369 52 240 4.97E-23 T 28-03-2018 WM46_RS11365 8dc91cd14bfa93041f84c87e7df9bdc2 213 Pfam PF01467 Cytidylyltransferase-like 7 187 2.0E-35 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS11365 8dc91cd14bfa93041f84c87e7df9bdc2 213 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 212 1.2E-60 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 WM46_RS11365 8dc91cd14bfa93041f84c87e7df9bdc2 213 SUPERFAMILY SSF52374 3 213 5.04E-59 T 28-03-2018 WM46_RS11365 8dc91cd14bfa93041f84c87e7df9bdc2 213 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 3 213 29.882 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 WM46_RS11365 8dc91cd14bfa93041f84c87e7df9bdc2 213 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 68 2.0E-12 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 WM46_RS11365 8dc91cd14bfa93041f84c87e7df9bdc2 213 Gene3D G3DSA:3.40.50.620 2 213 1.2E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS09810 fcea40517ef612782ebe71b9346e6831 297 Pfam PF01636 Phosphotransferase enzyme family 64 240 4.6E-6 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase WM46_RS09810 fcea40517ef612782ebe71b9346e6831 297 Gene3D G3DSA:1.20.1050.20 87 192 6.9E-4 T 28-03-2018 WM46_RS09810 fcea40517ef612782ebe71b9346e6831 297 SUPERFAMILY SSF56112 4 270 9.52E-25 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS24430 666b8725759451024ccf0365135d56f2 440 Pfam PF13416 Bacterial extracellular solute-binding protein 51 364 2.7E-40 T 28-03-2018 WM46_RS24430 666b8725759451024ccf0365135d56f2 440 Gene3D G3DSA:3.40.190.10 147 433 9.1E-49 T 28-03-2018 WM46_RS24430 666b8725759451024ccf0365135d56f2 440 SUPERFAMILY SSF53850 39 424 2.33E-74 T 28-03-2018 WM46_RS19455 546307c843832834cdbd3c57101d625a 483 Pfam PF05762 VWA domain containing CoxE-like protein 307 458 4.1E-10 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like WM46_RS19455 546307c843832834cdbd3c57101d625a 483 SMART SM00327 319 483 2.7E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS19455 546307c843832834cdbd3c57101d625a 483 Hamap MF_01626 Protein ViaA [viaA]. 1 483 59.246 T 28-03-2018 IPR023481 Uncharacterised protein family ViaA WM46_RS19455 546307c843832834cdbd3c57101d625a 483 Gene3D G3DSA:3.40.50.410 298 464 3.6E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS19455 546307c843832834cdbd3c57101d625a 483 SUPERFAMILY SSF53300 318 459 4.96E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS05515 ff57582633d4ba6a12fe83cc49e923c6 350 Gene3D G3DSA:3.40.50.1980 29 172 6.6E-28 T 28-03-2018 WM46_RS05515 ff57582633d4ba6a12fe83cc49e923c6 350 SUPERFAMILY SSF53807 53 338 1.26E-39 T 28-03-2018 WM46_RS05515 ff57582633d4ba6a12fe83cc49e923c6 350 Gene3D G3DSA:3.40.50.1980 173 341 1.8E-25 T 28-03-2018 WM46_RS05515 ff57582633d4ba6a12fe83cc49e923c6 350 Pfam PF01497 Periplasmic binding protein 56 313 1.5E-37 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS18520 46298e82821691bdef777d2592646da6 232 SMART SM00862 152 228 2.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS18520 46298e82821691bdef777d2592646da6 232 SMART SM00448 2 111 6.6E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS18520 46298e82821691bdef777d2592646da6 232 Pfam PF00072 Response regulator receiver domain 4 112 1.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 WM46_RS18520 46298e82821691bdef777d2592646da6 232 SUPERFAMILY SSF52172 2 188 9.96E-42 T 28-03-2018 IPR011006 CheY-like superfamily WM46_RS18520 46298e82821691bdef777d2592646da6 232 Gene3D G3DSA:1.10.10.10 120 232 5.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18520 46298e82821691bdef777d2592646da6 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 2.5E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS18520 46298e82821691bdef777d2592646da6 232 Gene3D G3DSA:3.40.50.2300 2 119 1.5E-38 T 28-03-2018 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 108 126 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 4 26 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 86 107 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 44 61 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 63 84 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 27 43 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PRINTS PR01004 Flagellar FliJ protein signature 126 146 2.7E-78 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 Pfam PF02050 Flagellar FliJ protein 19 141 5.0E-34 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 PIRSF PIRSF019404 1 147 6.9E-50 T 28-03-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 WM46_RS03815 98fa71495c7ed205020af0f46271eb36 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 4.9E-29 T 28-03-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 WM46_RS16080 cb7463933c1cc6fce82c8f5c606857f6 394 SUPERFAMILY SSF53383 4 393 1.77E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS16080 cb7463933c1cc6fce82c8f5c606857f6 394 Gene3D G3DSA:3.90.1150.10 272 394 7.8E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS16080 cb7463933c1cc6fce82c8f5c606857f6 394 Gene3D G3DSA:3.40.640.10 55 271 1.9E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS16080 cb7463933c1cc6fce82c8f5c606857f6 394 Pfam PF00155 Aminotransferase class I and II 57 389 2.5E-38 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS19060 ebe48fb9034fc411af66ea9eb5982d69 206 PIRSF PIRSF006324 1 205 1.8E-52 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS19060 ebe48fb9034fc411af66ea9eb5982d69 206 Pfam PF01810 LysE type translocator 14 202 8.0E-48 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS19060 ebe48fb9034fc411af66ea9eb5982d69 206 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 19 200 4.6E-57 T 28-03-2018 IPR004778 Homoserine/Threonine efflux protein GO:0016021 WM46_RS23595 f8ecbc8a35295b6bd041a9d247446a24 204 Pfam PF11726 Inovirus Gp2 27 173 2.5E-11 T 28-03-2018 WM46_RS15920 90bab8d8a5bb2dbd67057fc67c1bb9bb 162 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 16 153 5.5E-50 T 28-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE WM46_RS15920 90bab8d8a5bb2dbd67057fc67c1bb9bb 162 Pfam PF11939 [NiFe]-hydrogenase assembly, chaperone, HybE 12 155 1.8E-44 T 28-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE WM46_RS15920 90bab8d8a5bb2dbd67057fc67c1bb9bb 162 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 16 157 2.0E-69 T 28-03-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE WM46_RS20810 04989a133fdcba157bab47bf17475811 499 Pfam PF01384 Phosphate transporter family 30 488 2.8E-86 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 WM46_RS21410 2d5051c6de3debdcfff730e48e77fc53 265 Pfam PF03609 PTS system sorbose-specific iic component 6 237 1.1E-72 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS21410 2d5051c6de3debdcfff730e48e77fc53 265 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 1 264 1.1E-128 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS01855 5ec0a04edf0955ecd9012ba9fc1a75dd 252 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 14 250 2.1E-79 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 WM46_RS01855 5ec0a04edf0955ecd9012ba9fc1a75dd 252 Pfam PF12697 Alpha/beta hydrolase family 17 244 7.5E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS01855 5ec0a04edf0955ecd9012ba9fc1a75dd 252 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 251 33.778 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 WM46_RS01855 5ec0a04edf0955ecd9012ba9fc1a75dd 252 Gene3D G3DSA:3.40.50.1820 1 252 8.2E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS01855 5ec0a04edf0955ecd9012ba9fc1a75dd 252 SUPERFAMILY SSF53474 10 250 9.56E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS23970 357a754eec0df289d81c62f69cbc46a6 157 Hamap MF_01191 UPF0442 protein YjjB [yjjB]. 1 157 42.364 T 28-03-2018 IPR020914 Uncharacterised protein family UPF0442 WM46_RS23970 357a754eec0df289d81c62f69cbc46a6 157 Pfam PF12821 Threonine/Serine exporter, ThrE 13 147 1.6E-34 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE WM46_RS06795 5fe0d59927f35a84f28262d886583df4 218 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 7 206 3.1E-68 T 28-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 WM46_RS06795 5fe0d59927f35a84f28262d886583df4 218 Pfam PF01292 Prokaryotic cytochrome b561 13 186 2.8E-19 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM46_RS06795 5fe0d59927f35a84f28262d886583df4 218 Gene3D G3DSA:1.20.950.20 1 217 5.8E-56 T 28-03-2018 WM46_RS06795 5fe0d59927f35a84f28262d886583df4 218 SUPERFAMILY SSF81342 3 212 3.84E-54 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM46_RS04545 bd2bf7c5b6d85aff3ab0d01d7eea0692 81 SUPERFAMILY SSF47413 4 67 5.62E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS04545 bd2bf7c5b6d85aff3ab0d01d7eea0692 81 ProDom PD057771 CRO REGULATORY TRANSCRIPTION CP-933R REPRESSOR DNA-BINDING REGULATION BACTERIOPHAGE PROTEIN REGULATOR 15 66 2.0E-9 T 28-03-2018 IPR020114 Cro repressor, HK022-type WM46_RS04545 bd2bf7c5b6d85aff3ab0d01d7eea0692 81 Gene3D G3DSA:1.10.260.40 3 69 2.0E-10 T 28-03-2018 WM46_RS02940 0359e91456c3ac4d11c2490c4b791134 270 Pfam PF01370 NAD dependent epimerase/dehydratase family 45 201 9.9E-14 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 WM46_RS02940 0359e91456c3ac4d11c2490c4b791134 270 Gene3D G3DSA:3.90.25.10 139 265 2.3E-14 T 28-03-2018 WM46_RS02940 0359e91456c3ac4d11c2490c4b791134 270 Gene3D G3DSA:3.40.50.720 1 36 0.0055 T 28-03-2018 WM46_RS02940 0359e91456c3ac4d11c2490c4b791134 270 SUPERFAMILY SSF51735 1 256 2.84E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS02940 0359e91456c3ac4d11c2490c4b791134 270 Gene3D G3DSA:3.40.50.720 37 138 6.4E-5 T 28-03-2018 WM46_RS16620 5479941558350adef704208367b7eee7 384 Pfam PF01380 SIS domain 223 355 3.2E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS16620 5479941558350adef704208367b7eee7 384 Pfam PF01380 SIS domain 49 188 5.2E-28 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS16620 5479941558350adef704208367b7eee7 384 SUPERFAMILY SSF53697 15 373 6.33E-52 T 28-03-2018 WM46_RS16620 5479941558350adef704208367b7eee7 384 TIGRFAM TIGR02815 agaS_fam: putative sugar isomerase, AgaS family 13 382 1.2E-183 T 28-03-2018 IPR014180 Sugar isomerase, AgaS GO:0016861 WM46_RS16620 5479941558350adef704208367b7eee7 384 Gene3D G3DSA:3.40.50.10490 13 189 8.2E-26 T 28-03-2018 WM46_RS16620 5479941558350adef704208367b7eee7 384 Gene3D G3DSA:3.40.50.10490 223 373 3.7E-19 T 28-03-2018 WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 Pfam PF13410 Glutathione S-transferase, C-terminal domain 203 257 4.3E-12 T 28-03-2018 WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 SUPERFAMILY SSF47616 173 324 1.39E-35 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 Gene3D G3DSA:3.40.30.10 42 188 1.0E-36 T 28-03-2018 WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 PIRSF PIRSF015753 5 324 2.3E-134 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 Gene3D G3DSA:1.20.1050.10 189 326 8.1E-42 T 28-03-2018 WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 158 9.3E-23 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 SUPERFAMILY SSF52833 41 99 8.2E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS16450 472c64b1d29a8f14cced9f6401a2c4f4 329 SUPERFAMILY SSF52833 126 162 8.2E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS15830 aba97b6ed392ddca2107a08dba8cfe50 304 Gene3D G3DSA:3.40.50.300 58 237 2.7E-25 T 28-03-2018 WM46_RS15830 aba97b6ed392ddca2107a08dba8cfe50 304 Gene3D G3DSA:3.40.50.300 19 57 6.8E-4 T 28-03-2018 WM46_RS15830 aba97b6ed392ddca2107a08dba8cfe50 304 Pfam PF01926 50S ribosome-binding GTPase 48 136 1.4E-14 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS15830 aba97b6ed392ddca2107a08dba8cfe50 304 SUPERFAMILY SSF52540 31 173 2.18E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS04225 21d32fb57d2416d02d5917f253bf5d21 130 Pfam PF06366 Flagellar protein FlhE 28 130 3.5E-38 T 28-03-2018 IPR009420 Flagellar protein FlhE WM46_RS00855 c19bdb1167e9bde79694323f86be9495 344 Pfam PF06804 NlpB/DapX lipoprotein 40 342 5.4E-110 T 28-03-2018 IPR010653 NlpB/DapX lipoprotein WM46_RS00855 c19bdb1167e9bde79694323f86be9495 344 Hamap MF_00924 Outer membrane protein assembly factor BamC [bamC]. 9 343 38.404 T 28-03-2018 IPR014524 Outer membrane protein assembly factor BamC WM46_RS00855 c19bdb1167e9bde79694323f86be9495 344 PIRSF PIRSF026343 9 344 1.1E-141 T 28-03-2018 IPR014524 Outer membrane protein assembly factor BamC WM46_RS21030 c18e8f505f95381012b3c214b2cfa2cf 330 Gene3D G3DSA:1.10.3470.10 30 323 2.5E-22 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS21030 c18e8f505f95381012b3c214b2cfa2cf 330 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 312 4.9E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS17060 1af64d519837acd8d674c5db45118123 375 Gene3D G3DSA:3.40.50.300 21 372 1.3E-13 T 28-03-2018 WM46_RS17060 1af64d519837acd8d674c5db45118123 375 Pfam PF03969 AFG1-like ATPase 5 372 2.9E-159 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 WM46_RS17060 1af64d519837acd8d674c5db45118123 375 Hamap MF_01919 Cell division protein ZapE [zapE]. 4 375 53.05 T 28-03-2018 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 WM46_RS17060 1af64d519837acd8d674c5db45118123 375 SUPERFAMILY SSF52540 67 208 1.23E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 Gene3D G3DSA:1.20.120.530 72 228 4.8E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 SUPERFAMILY SSF46785 7 102 9.46E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 SUPERFAMILY SSF48008 82 213 1.18E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 SMART SM00895 85 209 2.9E-18 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 Gene3D G3DSA:1.10.10.10 1 71 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 SMART SM00345 17 75 5.6E-22 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 5.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS07160 1c38f9084a50e7f48cedbd17adfbcf4a 228 Pfam PF07729 FCD domain 89 208 1.3E-25 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS09995 540437b4339f9dac28dc59ec224a0879 223 Pfam PF03483 B3/4 domain 60 192 1.0E-19 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 WM46_RS09995 540437b4339f9dac28dc59ec224a0879 223 SUPERFAMILY SSF56037 56 210 1.8E-26 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 WM46_RS09995 540437b4339f9dac28dc59ec224a0879 223 Gene3D G3DSA:3.50.40.10 56 211 1.3E-22 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 WM46_RS09995 540437b4339f9dac28dc59ec224a0879 223 SMART SM00873 59 213 3.2E-7 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 WM46_RS25400 a18a404eebfea658e60332b14fa3dc08 307 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 194 207 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25400 a18a404eebfea658e60332b14fa3dc08 307 Pfam PF00146 NADH dehydrogenase 10 301 8.6E-49 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 SUPERFAMILY SSF53597 5 159 4.97E-43 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 17 39 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 Pfam PF00186 Dihydrofolate reductase 6 158 4.5E-39 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 Gene3D G3DSA:3.40.430.10 1 158 2.9E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 PRINTS PR00070 Dihydrofolate reductase signature 44 55 1.3E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 PRINTS PR00070 Dihydrofolate reductase signature 17 27 1.3E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 PRINTS PR00070 Dihydrofolate reductase signature 31 39 1.3E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS25895 f617c3a5aa6cfdafe95cd52a16b92b0b 160 PRINTS PR00070 Dihydrofolate reductase signature 96 110 1.3E-11 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 WM46_RS19290 6f6f90bc64a94a0c6c82637c5e649cd8 242 Pfam PF04973 Nicotinamide mononucleotide transporter 23 226 6.8E-53 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 WM46_RS19290 6f6f90bc64a94a0c6c82637c5e649cd8 242 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 22 230 2.0E-61 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 WM46_RS04005 0c039db9faafb46ff7d53fc857aa4715 206 Pfam PF01810 LysE type translocator 13 202 7.6E-32 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS00225 e1b08bfa697e1b79a386ed3b7cad57a4 172 Pfam PF13689 Domain of unknown function (DUF4154) 34 167 4.5E-29 T 28-03-2018 IPR025293 Protein of unknown function DUF4154 WM46_RS23605 67c38b9d3eb27b5cafaff0a63f879eb2 295 Gene3D G3DSA:3.40.50.300 49 228 6.0E-27 T 28-03-2018 WM46_RS23605 67c38b9d3eb27b5cafaff0a63f879eb2 295 SUPERFAMILY SSF52540 25 207 2.81E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS23605 67c38b9d3eb27b5cafaff0a63f879eb2 295 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 103 7.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS23605 67c38b9d3eb27b5cafaff0a63f879eb2 295 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 39 59 7.7E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS23605 67c38b9d3eb27b5cafaff0a63f879eb2 295 Pfam PF01926 50S ribosome-binding GTPase 39 155 8.9E-16 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 WM46_RS23605 67c38b9d3eb27b5cafaff0a63f879eb2 295 Gene3D G3DSA:3.40.50.300 13 48 0.0014 T 28-03-2018 WM46_RS10465 679c19cdbe9d2fb29c05db9dd5e50468 473 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 28 467 3.8E-109 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS10465 679c19cdbe9d2fb29c05db9dd5e50468 473 Pfam PF00939 Sodium:sulfate symporter transmembrane region 10 471 6.3E-123 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS10465 679c19cdbe9d2fb29c05db9dd5e50468 473 PIRSF PIRSF002457 1 473 3.5E-147 T 28-03-2018 IPR030676 Citrate carrier CitT-related WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 SUPERFAMILY SSF52540 6 232 6.45E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 SMART SM00382 281 476 4.0E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 SMART SM00382 32 220 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 Gene3D G3DSA:3.40.50.300 261 497 1.9E-34 T 28-03-2018 WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 Gene3D G3DSA:3.40.50.300 1 246 1.7E-49 T 28-03-2018 WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 SUPERFAMILY SSF52540 275 484 4.17E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 Pfam PF00005 ABC transporter 275 427 1.2E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 Pfam PF00005 ABC transporter 23 172 3.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS04080 93ce53a536e5f79b530c599cfbdeea68 504 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS02470 91fa24c48345ca13eb47be32f640cd5e 336 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 325 5.8E-48 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS02470 91fa24c48345ca13eb47be32f640cd5e 336 Gene3D G3DSA:1.10.3470.10 34 331 1.9E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS25385 3ed93633ffd4cc9c33cc97c33d6fb500 153 Pfam PF11046 Transcriptional repressor of hyc and hyp operons 1 145 7.5E-73 T 28-03-2018 IPR021285 Transcription regulator, HycA WM46_RS13965 4106b18b45feb4726ace992d1b1fafe7 241 SUPERFAMILY SSF53633 7 240 4.19E-72 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS13965 4106b18b45feb4726ace992d1b1fafe7 241 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.497 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 WM46_RS13965 4106b18b45feb4726ace992d1b1fafe7 241 Pfam PF00696 Amino acid kinase family 10 219 1.3E-27 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase WM46_RS13965 4106b18b45feb4726ace992d1b1fafe7 241 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 4.8E-104 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 WM46_RS13965 4106b18b45feb4726ace992d1b1fafe7 241 Gene3D G3DSA:3.40.1160.10 2 241 3.7E-43 T 28-03-2018 WM46_RS13965 4106b18b45feb4726ace992d1b1fafe7 241 PIRSF PIRSF005650 4 241 5.5E-89 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 WM46_RS25065 2637eb06b4ab9a4349843172ecda3b28 109 PIRSF PIRSF006257 1 108 4.8E-40 T 28-03-2018 IPR007384 Protein of unknown function UCP006257 WM46_RS25065 2637eb06b4ab9a4349843172ecda3b28 109 Gene3D G3DSA:1.20.1440.40 3 104 1.3E-39 T 28-03-2018 IPR023376 YqcC-like domain WM46_RS25065 2637eb06b4ab9a4349843172ecda3b28 109 SUPERFAMILY SSF158452 1 107 6.15E-38 T 28-03-2018 IPR023376 YqcC-like domain WM46_RS25065 2637eb06b4ab9a4349843172ecda3b28 109 Pfam PF04287 tRNA pseudouridine synthase C 7 103 1.2E-34 T 28-03-2018 IPR023376 YqcC-like domain WM46_RS09800 07bc442f335efe67a7b8ff1d65b9bf44 259 Gene3D G3DSA:3.40.50.150 8 259 6.8E-57 T 28-03-2018 WM46_RS09800 07bc442f335efe67a7b8ff1d65b9bf44 259 SUPERFAMILY SSF53335 6 248 3.53E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS09800 07bc442f335efe67a7b8ff1d65b9bf44 259 Hamap MF_02057 tRNA 5-carboxymethoxyuridine methyltransferase [cmoM]. 2 255 43.573 T 28-03-2018 IPR033664 tRNA 5-carboxymethoxyuridine methyltransferase GO:0008168 WM46_RS09800 07bc442f335efe67a7b8ff1d65b9bf44 259 Pfam PF13847 Methyltransferase domain 44 151 4.6E-19 T 28-03-2018 IPR025714 Methyltransferase domain WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 57 69 7.6E-35 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 42 57 7.6E-35 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 26 42 7.6E-35 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01591 DNA-binding protein FIS signature 9 26 7.6E-35 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 Pfam PF02954 Bacterial regulatory protein, Fis family 55 95 3.8E-14 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 Gene3D G3DSA:1.10.10.60 1 98 4.2E-27 T 28-03-2018 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 SUPERFAMILY SSF46689 4 98 3.88E-27 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PIRSF PIRSF002097 1 98 4.9E-46 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 78 98 8.3E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 61 78 8.3E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 WM46_RS17250 e9ff87b2f6cbc07850e519f60813e1f6 98 Hamap MF_00166 DNA-binding protein Fis [fis]. 1 98 33.769 T 28-03-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 WM46_RS02660 721ae2363e9790620395ef14891a849f 108 Gene3D G3DSA:3.10.450.160 26 104 3.2E-13 T 28-03-2018 WM46_RS02660 721ae2363e9790620395ef14891a849f 108 Pfam PF11776 Nickel/cobalt transporter regulator 48 97 2.0E-19 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB WM46_RS02660 721ae2363e9790620395ef14891a849f 108 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 28 97 6.0E-32 T 28-03-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB WM46_RS02395 bbe2781cd37905dad3d21aa9a4f36c3f 416 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.0E-21 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 WM46_RS02395 bbe2781cd37905dad3d21aa9a4f36c3f 416 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 201 412 1.1E-65 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 WM46_RS02395 bbe2781cd37905dad3d21aa9a4f36c3f 416 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 412 6.6E-153 T 28-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 WM46_RS17520 d44845a02f8ee59d1e9b327b0534f8f6 110 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 7.6E-38 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 WM46_RS17520 d44845a02f8ee59d1e9b327b0534f8f6 110 SUPERFAMILY SSF54843 1 109 4.06E-43 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 WM46_RS17520 d44845a02f8ee59d1e9b327b0534f8f6 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.1E-51 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS17520 d44845a02f8ee59d1e9b327b0534f8f6 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17520 d44845a02f8ee59d1e9b327b0534f8f6 110 Gene3D G3DSA:3.90.470.10 1 110 3.3E-43 T 28-03-2018 WM46_RS17520 d44845a02f8ee59d1e9b327b0534f8f6 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.067 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 82 100 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 207 232 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 190 206 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 59 81 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 139 161 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 162 189 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 5 24 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 101 120 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 PRINTS PR01003 Flagellar assembly protein FliH signature 121 138 1.9E-116 T 28-03-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 WM46_RS03825 d3d881f3b6d6c2aad0dd8cb3dbabd37b 234 Pfam PF02108 Flagellar assembly protein FliH 102 225 2.8E-41 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE WM46_RS07175 eceb3d30a5cfc17aaccf67a8c25b59d7 445 Pfam PF07690 Major Facilitator Superfamily 252 433 1.1E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS07175 eceb3d30a5cfc17aaccf67a8c25b59d7 445 SUPERFAMILY SSF103473 13 435 5.62E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07175 eceb3d30a5cfc17aaccf67a8c25b59d7 445 Gene3D G3DSA:1.20.1250.20 13 233 1.0E-26 T 28-03-2018 WM46_RS07175 eceb3d30a5cfc17aaccf67a8c25b59d7 445 Pfam PF00083 Sugar (and other) transporter 25 238 2.1E-26 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 WM46_RS07175 eceb3d30a5cfc17aaccf67a8c25b59d7 445 Gene3D G3DSA:1.20.1250.20 247 444 1.5E-23 T 28-03-2018 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 2 120 2.2E-47 T 28-03-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 SUPERFAMILY SSF52440 2 122 5.47E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 Gene3D G3DSA:3.40.50.20 2 129 2.1E-52 T 28-03-2018 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 Hamap MF_00162 Glutathione synthetase [gshB]. 1 315 182.691 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 124 296 1.6E-79 T 28-03-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 TIGRFAM TIGR01380 glut_syn: glutathione synthase 2 311 3.2E-140 T 28-03-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 SUPERFAMILY SSF56059 123 312 3.31E-60 T 28-03-2018 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 Gene3D G3DSA:3.30.1490.20 138 191 1.2E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 WM46_RS15060 ef3c330d28c4e666b89736b34b0efaf5 315 Gene3D G3DSA:3.30.470.20 192 300 8.8E-17 T 28-03-2018 WM46_RS10505 56184ab81b056e04feec1d7943e33192 377 Gene3D G3DSA:3.40.1710.10 45 196 4.9E-23 T 28-03-2018 WM46_RS10505 56184ab81b056e04feec1d7943e33192 377 Pfam PF12698 ABC-2 family transporter protein 29 370 1.1E-37 T 28-03-2018 WM46_RS06400 ca3d2d3d4e7017a15f249d8d07c18c83 302 Pfam PF01368 DHH family 2 144 5.8E-14 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS06400 ca3d2d3d4e7017a15f249d8d07c18c83 302 SUPERFAMILY SSF64182 1 292 1.03E-55 T 28-03-2018 WM46_RS06400 ca3d2d3d4e7017a15f249d8d07c18c83 302 SMART SM01131 179 296 2.5E-33 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS06400 ca3d2d3d4e7017a15f249d8d07c18c83 302 Pfam PF02833 DHHA2 domain 181 293 2.2E-16 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS06400 ca3d2d3d4e7017a15f249d8d07c18c83 302 Gene3D G3DSA:3.90.1640.10 1 186 1.1E-45 T 28-03-2018 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 TIGRFAM TIGR01230 agmatinase: agmatinase 22 299 1.6E-117 T 28-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 PIRSF PIRSF036979 13 304 2.2E-102 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 Pfam PF00491 Arginase family 34 297 3.6E-86 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 SUPERFAMILY SSF52768 13 301 2.16E-91 T 28-03-2018 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 Gene3D G3DSA:3.40.800.10 5 306 2.5E-93 T 28-03-2018 WM46_RS15010 2d9dad66996863ec3df70e13e80d8814 306 Hamap MF_01418 Agmatinase [speB]. 1 304 70.453 T 28-03-2018 IPR023694 Agmatinase GO:0008783|GO:0009446|GO:0030145 KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305 WM46_RS21900 d966c7b44ab04c65b4a021dc4fe336bf 148 SUPERFAMILY SSF54593 2 139 1.34E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS21900 d966c7b44ab04c65b4a021dc4fe336bf 148 Gene3D G3DSA:3.10.180.10 7 148 2.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS21900 d966c7b44ab04c65b4a021dc4fe336bf 148 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 138 4.8E-5 T 28-03-2018 IPR028973 PhnB-like WM46_RS11095 27323c317a8c2351aadfff77f100d730 559 PIRSF PIRSF001294 1 559 3.8E-229 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 WM46_RS11095 27323c317a8c2351aadfff77f100d730 559 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 1 558 1.1E-286 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 WM46_RS11095 27323c317a8c2351aadfff77f100d730 559 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 558 34.594 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 WM46_RS11095 27323c317a8c2351aadfff77f100d730 559 Gene3D G3DSA:1.10.287.70 276 516 0.055 T 28-03-2018 WM46_RS11095 27323c317a8c2351aadfff77f100d730 559 Pfam PF03814 Potassium-transporting ATPase A subunit 12 556 3.1E-236 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 Gene3D G3DSA:1.20.1080.10 3 229 2.9E-25 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 PRINTS PR00783 Major intrinsic protein family signature 84 103 3.5E-15 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 PRINTS PR00783 Major intrinsic protein family signature 140 158 3.5E-15 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 PRINTS PR00783 Major intrinsic protein family signature 7 26 3.5E-15 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 PRINTS PR00783 Major intrinsic protein family signature 47 71 3.5E-15 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 PRINTS PR00783 Major intrinsic protein family signature 204 224 3.5E-15 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 Pfam PF00230 Major intrinsic protein 8 219 4.6E-14 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 WM46_RS22480 aa95f0f5eb59e1d6118c0a43e240d777 233 SUPERFAMILY SSF81338 7 226 4.84E-28 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS15045 46cd9f4e9c1e2988bab6754f66178318 166 Pfam PF10263 SprT-like family 22 118 1.7E-16 T 28-03-2018 IPR006640 SprT-like WM46_RS15045 46cd9f4e9c1e2988bab6754f66178318 166 Hamap MF_00746 Protein SprT [sprT]. 12 165 40.49 T 28-03-2018 IPR023483 Uncharacterised protein family SprT WM46_RS15045 46cd9f4e9c1e2988bab6754f66178318 166 SMART SM00731 16 165 2.7E-61 T 28-03-2018 IPR006640 SprT-like WM46_RS15045 46cd9f4e9c1e2988bab6754f66178318 166 Pfam PF17283 SprT-like zinc ribbon domain 126 164 1.4E-10 T 28-03-2018 IPR035240 SprT-like, zinc ribbon domain WM46_RS23090 b37ba6258dc88d60de5168a97bf22440 514 Gene3D G3DSA:1.20.1250.20 231 461 2.0E-9 T 28-03-2018 WM46_RS23090 b37ba6258dc88d60de5168a97bf22440 514 Pfam PF13347 MFS/sugar transport protein 17 454 5.6E-46 T 28-03-2018 WM46_RS23090 b37ba6258dc88d60de5168a97bf22440 514 Gene3D G3DSA:1.20.1250.20 12 216 2.2E-19 T 28-03-2018 WM46_RS23090 b37ba6258dc88d60de5168a97bf22440 514 SUPERFAMILY SSF103473 14 452 2.35E-30 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS07225 b51c0bd0f1a8f8b036a3774b00812c9c 285 Gene3D G3DSA:1.20.1630.10 2 283 1.6E-39 T 28-03-2018 WM46_RS07225 b51c0bd0f1a8f8b036a3774b00812c9c 285 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 275 1.4E-103 T 28-03-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 WM46_RS09400 5cac0fb9dfb45de98d224f13a22003fb 408 Gene3D G3DSA:1.20.1250.20 207 406 8.5E-23 T 28-03-2018 WM46_RS09400 5cac0fb9dfb45de98d224f13a22003fb 408 Gene3D G3DSA:1.20.1250.20 5 199 1.8E-20 T 28-03-2018 WM46_RS09400 5cac0fb9dfb45de98d224f13a22003fb 408 Pfam PF07690 Major Facilitator Superfamily 26 277 4.8E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS09400 5cac0fb9dfb45de98d224f13a22003fb 408 SUPERFAMILY SSF103473 9 405 2.88E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS13475 10d02ee653f5604c9812a02776288ea6 681 Gene3D G3DSA:3.40.50.1110 435 678 1.1E-7 T 28-03-2018 WM46_RS13475 10d02ee653f5604c9812a02776288ea6 681 Pfam PF01757 Acyltransferase family 32 364 1.7E-30 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 WM46_RS23025 519ee75fbffec2dab25b0882809f2839 469 ProSitePatterns PS00218 Amino acid permeases signature. 52 82 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS23025 519ee75fbffec2dab25b0882809f2839 469 PIRSF PIRSF006060 1 469 3.8E-69 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS23025 519ee75fbffec2dab25b0882809f2839 469 Pfam PF00324 Amino acid permease 27 465 1.0E-122 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 PRINTS PR00969 Pili chaperone signature 23 32 1.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 PRINTS PR00969 Pili chaperone signature 122 137 1.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 PRINTS PR00969 Pili chaperone signature 98 115 1.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 PRINTS PR00969 Pili chaperone signature 157 172 1.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 PRINTS PR00969 Pili chaperone signature 70 91 1.5E-36 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 SUPERFAMILY SSF49584 141 217 1.57E-22 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 SUPERFAMILY SSF49354 17 140 6.02E-44 T 28-03-2018 IPR008962 PapD-like WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 Gene3D G3DSA:2.60.40.10 23 138 8.9E-40 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 Gene3D G3DSA:2.60.40.10 142 221 8.8E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 22 141 6.0E-45 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS24645 d166b055e78d1cb29eb5a36000b4fee6 221 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 163 216 3.5E-14 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 SUPERFAMILY SSF52777 465 641 2.0E-33 T 28-03-2018 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 SUPERFAMILY SSF52777 646 895 4.22E-29 T 28-03-2018 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 ProSitePatterns PS00012 Phosphopantetheine attachment site. 400 415 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 Gene3D G3DSA:1.10.1200.10 371 448 4.3E-18 T 28-03-2018 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 Pfam PF00550 Phosphopantetheine attachment site 377 440 2.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 SUPERFAMILY SSF52777 18 166 1.56E-8 T 28-03-2018 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 Gene3D G3DSA:3.30.559.10 454 648 1.1E-26 T 28-03-2018 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 Gene3D G3DSA:3.30.559.10 11 183 6.0E-8 T 28-03-2018 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 SMART SM00823 Phosphopantetheine attachment site 375 445 0.0026 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 Pfam PF00668 Condensation domain 462 892 4.4E-47 T 28-03-2018 IPR001242 Condensation domain WM46_RS13295 b7b73e8663acafadcdd28cb38b0edbd2 919 SUPERFAMILY SSF47336 374 439 9.68E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 112 282 4.4E-26 T 28-03-2018 WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 SUPERFAMILY SSF56784 111 315 4.47E-46 T 28-03-2018 IPR023214 HAD-like domain WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 Gene3D G3DSA:1.10.150.210 135 169 1.1E-23 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 Gene3D G3DSA:3.40.50.1000 170 315 1.6E-25 T 28-03-2018 IPR023214 HAD-like domain WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 97 315 1.9E-93 T 28-03-2018 WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 Pfam PF12710 haloacid dehalogenase-like hydrolase 116 280 2.3E-17 T 28-03-2018 WM46_RS24125 5eaf2c786d2e0525388a58106aa552b5 322 Gene3D G3DSA:3.30.70.260 88 134 0.0017 T 28-03-2018 WM46_RS18470 b70a8403c65127295397fa56933009d1 434 Pfam PF00939 Sodium:sulfate symporter transmembrane region 15 433 1.9E-20 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS08100 f226df9eadafe1157416b63bc6224ad6 196 PIRSF PIRSF030780 1 195 5.0E-124 T 28-03-2018 IPR016956 Inner membrane protein YdjM WM46_RS08100 f226df9eadafe1157416b63bc6224ad6 196 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 161 7.4E-34 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 SUPERFAMILY SSF51735 17 260 6.8E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 Gene3D G3DSA:3.40.50.720 58 261 5.6E-53 T 28-03-2018 WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 Gene3D G3DSA:3.40.50.720 11 57 5.5E-9 T 28-03-2018 WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 5.7E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 5.7E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 5.7E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 5.7E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 5.7E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.7E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 258 1.9E-54 T 28-03-2018 WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 7.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 7.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 7.6E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS25165 f3b01212d2dec7e24eff1d97b3bc71a4 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS02680 87e539b6021f1ca0c301f14df95805ba 266 Gene3D G3DSA:3.40.1190.20 1 266 8.8E-65 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02680 87e539b6021f1ca0c301f14df95805ba 266 SUPERFAMILY SSF53613 5 265 6.24E-82 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS02680 87e539b6021f1ca0c301f14df95805ba 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 1.2E-105 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 WM46_RS02680 87e539b6021f1ca0c301f14df95805ba 266 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 2.9E-94 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 WM46_RS25950 d989b5a245ef4cf1fda4354f86e5ad36 103 Gene3D G3DSA:1.20.120.330 9 78 6.5E-4 T 28-03-2018 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 SUPERFAMILY SSF51215 19 138 1.44E-20 T 28-03-2018 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 Pfam PF12833 Helix-turn-helix domain 186 263 1.9E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 Pfam PF02311 AraC-like ligand binding domain 30 147 2.9E-18 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 SUPERFAMILY SSF46689 217 264 2.02E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 Gene3D G3DSA:1.10.10.60 169 216 2.0E-9 T 28-03-2018 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 Gene3D G3DSA:1.10.10.60 217 270 1.3E-8 T 28-03-2018 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 SMART SM00342 180 262 6.3E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 258 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 Gene3D G3DSA:2.60.120.280 17 168 2.1E-16 T 28-03-2018 WM46_RS23860 87457bb653a9a7dc2e3d07e80e92709a 271 SUPERFAMILY SSF46689 170 213 7.17E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05465 ce0e4711db5ee6ee5af52114e76b8fe8 391 Pfam PF00589 Phage integrase family 204 367 1.1E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS05465 ce0e4711db5ee6ee5af52114e76b8fe8 391 Gene3D G3DSA:1.10.443.10 201 382 1.1E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS05465 ce0e4711db5ee6ee5af52114e76b8fe8 391 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 98 150 7.3E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS05465 ce0e4711db5ee6ee5af52114e76b8fe8 391 SUPERFAMILY SSF56349 97 377 4.12E-57 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS05465 ce0e4711db5ee6ee5af52114e76b8fe8 391 Gene3D G3DSA:1.10.150.130 87 200 6.0E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS05465 ce0e4711db5ee6ee5af52114e76b8fe8 391 Pfam PF13356 Arm DNA-binding domain 2 85 7.1E-20 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS15205 5de0f3fae7a5e5e25cd8e4ef038520b8 327 Pfam PF00107 Zinc-binding dehydrogenase 157 279 5.9E-18 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 WM46_RS15205 5de0f3fae7a5e5e25cd8e4ef038520b8 327 SUPERFAMILY SSF51735 118 284 4.77E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS15205 5de0f3fae7a5e5e25cd8e4ef038520b8 327 SUPERFAMILY SSF50129 1 152 7.46E-32 T 28-03-2018 IPR011032 GroES-like WM46_RS15205 5de0f3fae7a5e5e25cd8e4ef038520b8 327 Gene3D G3DSA:3.90.180.10 1 327 8.1E-60 T 28-03-2018 WM46_RS15205 5de0f3fae7a5e5e25cd8e4ef038520b8 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 3.2E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 WM46_RS15205 5de0f3fae7a5e5e25cd8e4ef038520b8 327 SMART SM00829 11 325 1.6E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 6 453 1.2E-199 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 SUPERFAMILY SSF52540 109 379 1.86E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 29 450 2.1E-196 T 28-03-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 SMART SM00382 174 357 8.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 Gene3D G3DSA:3.40.50.300 48 373 2.6E-81 T 28-03-2018 WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 162 373 2.1E-70 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS03820 5b35800c12d5c77851c71c8eaaf19f79 456 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 364 373 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 WM46_RS15855 a0b131357d7000f77db9a8660a644122 76 Pfam PF06006 Bacterial protein of unknown function (DUF905) 9 74 9.8E-36 T 28-03-2018 IPR009253 Protein of unknown function DUF905 WM46_RS15855 a0b131357d7000f77db9a8660a644122 76 SUPERFAMILY SSF54786 12 75 7.45E-29 T 28-03-2018 WM46_RS15855 a0b131357d7000f77db9a8660a644122 76 Gene3D G3DSA:3.30.160.130 7 75 7.5E-38 T 28-03-2018 WM46_RS15855 a0b131357d7000f77db9a8660a644122 76 ProDom PD028015 PLASMID YKFF YDEA R0111 YPJI YPMT1.60C C4569 AEC70 PSLT067 YFJA 9 75 4.0E-21 T 28-03-2018 IPR009253 Protein of unknown function DUF905 WM46_RS24020 51a68d0315721eddd4353cd622186773 91 ProDom PD058594 MEMBRANE INNER C5447 MAJOR ECS5328 THE SUPERFAMILY PERMEASES STY4905 YJJZ 14 91 1.0E-22 T 28-03-2018 IPR009885 Protein of unknown function DUF1435 WM46_RS24020 51a68d0315721eddd4353cd622186773 91 Pfam PF07256 Protein of unknown function (DUF1435) 14 88 1.7E-34 T 28-03-2018 IPR009885 Protein of unknown function DUF1435 WM46_RS19240 a80e3b6f4a4118483fa07a5a8b401ace 376 Gene3D G3DSA:3.40.50.2000 1 210 2.5E-79 T 28-03-2018 WM46_RS19240 a80e3b6f4a4118483fa07a5a8b401ace 376 SUPERFAMILY SSF53756 2 371 1.36E-141 T 28-03-2018 WM46_RS19240 a80e3b6f4a4118483fa07a5a8b401ace 376 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 372 1.5E-180 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 WM46_RS19240 a80e3b6f4a4118483fa07a5a8b401ace 376 Gene3D G3DSA:3.40.50.2000 211 356 6.4E-38 T 28-03-2018 WM46_RS19240 a80e3b6f4a4118483fa07a5a8b401ace 376 Hamap MF_02028 UDP-N-acetylglucosamine 2-epimerase [wecB]. 16 374 66.765 T 28-03-2018 IPR032892 UDP-N-acetylglucosamine 2-epimerase WecB GO:0008761|GO:0009246 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 WM46_RS19240 a80e3b6f4a4118483fa07a5a8b401ace 376 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 370 5.2E-129 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 WM46_RS07085 bf7ef73997203d37af7a841c14d12276 72 ProDom PD027692 ANTIBIOTIC RESISTANCE MULTIPLE MARB 17 72 2.0E-17 T 28-03-2018 IPR025732 MarB protein WM46_RS07085 bf7ef73997203d37af7a841c14d12276 72 Pfam PF13999 MarB protein 6 70 1.6E-34 T 28-03-2018 IPR025732 MarB protein WM46_RS14385 6d1a4dc02f14db78f04966e28c9c6ce5 414 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 359 383 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 WM46_RS14385 6d1a4dc02f14db78f04966e28c9c6ce5 414 Pfam PF01098 Cell cycle protein 48 402 1.6E-128 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 WM46_RS14385 6d1a4dc02f14db78f04966e28c9c6ce5 414 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 43 410 42.09 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 WM46_RS14385 6d1a4dc02f14db78f04966e28c9c6ce5 414 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 45 400 1.6E-134 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 WM46_RS14135 86a157a5840723548d3d44f1030d66c8 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 1.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS14135 86a157a5840723548d3d44f1030d66c8 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 139 163 1.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS14135 86a157a5840723548d3d44f1030d66c8 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 1.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS14135 86a157a5840723548d3d44f1030d66c8 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 1.4E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS14135 86a157a5840723548d3d44f1030d66c8 256 Pfam PF01061 ABC-2 type transporter 9 218 2.2E-38 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 WM46_RS14135 86a157a5840723548d3d44f1030d66c8 256 PIRSF PIRSF006648 11 252 3.6E-22 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 WM46_RS11800 c12dc3ba81eb6c21e0b5f90b79b2ac89 462 PIRSF PIRSF006060 3 462 1.2E-78 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 WM46_RS11800 c12dc3ba81eb6c21e0b5f90b79b2ac89 462 Pfam PF00324 Amino acid permease 31 461 9.7E-119 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 WM46_RS11800 c12dc3ba81eb6c21e0b5f90b79b2ac89 462 ProSitePatterns PS00218 Amino acid permeases signature. 56 86 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 WM46_RS25505 8a06bbf1e01ec36dafc208e8fefc44d6 187 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 181 4.6E-112 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 WM46_RS25505 8a06bbf1e01ec36dafc208e8fefc44d6 187 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 5 171 4.3E-76 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 WM46_RS25505 8a06bbf1e01ec36dafc208e8fefc44d6 187 PIRSF PIRSF038321 2 182 4.0E-89 T 28-03-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 WM46_RS01475 cb6999881831a9975cb73fa8146e90b7 94 TIGRFAM TIGR00743 TIGR00743: conserved hypothetical protein 1 94 4.6E-45 T 28-03-2018 IPR005272 Conserved hypothetical protein CHP00743 WM46_RS01475 cb6999881831a9975cb73fa8146e90b7 94 Pfam PF04175 Protein of unknown function (DUF406) 3 94 1.2E-38 T 28-03-2018 IPR005272 Conserved hypothetical protein CHP00743 WM46_RS01475 cb6999881831a9975cb73fa8146e90b7 94 Gene3D G3DSA:3.30.70.860 15 94 2.3E-33 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain WM46_RS21580 df90d85650aba014abf78521bca442f7 290 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 5 288 30.247 T 28-03-2018 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 WM46_RS21580 df90d85650aba014abf78521bca442f7 290 Pfam PF01040 UbiA prenyltransferase family 28 271 4.6E-69 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 WM46_RS21580 df90d85650aba014abf78521bca442f7 290 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 67 89 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site WM46_RS21580 df90d85650aba014abf78521bca442f7 290 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 11 287 8.9E-111 T 28-03-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 WM46_RS01040 a83dccf754c25f0c6b4e878492383138 289 SUPERFAMILY SSF53187 200 277 3.77E-54 T 28-03-2018 WM46_RS01040 a83dccf754c25f0c6b4e878492383138 289 SUPERFAMILY SSF53187 57 152 3.77E-54 T 28-03-2018 WM46_RS01040 a83dccf754c25f0c6b4e878492383138 289 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 59 273 6.5E-52 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM46_RS01040 a83dccf754c25f0c6b4e878492383138 289 SMART SM00646 118 273 3.9E-68 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 WM46_RS01040 a83dccf754c25f0c6b4e878492383138 289 Gene3D G3DSA:3.40.630.40 44 277 5.6E-57 T 28-03-2018 WM46_RS02240 4ff0ff5031e885f0cb48b0b83eca3a89 335 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 3 330 47.099 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 WM46_RS02240 4ff0ff5031e885f0cb48b0b83eca3a89 335 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 324 7.9E-97 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 Pfam PF00206 Lyase 6 301 3.1E-100 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 Gene3D G3DSA:1.10.275.10 2 107 8.6E-32 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 41.44 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 Gene3D G3DSA:1.10.40.30 376 433 6.7E-26 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 456 1.5E-214 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 2.7E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 2.7E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 2.7E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.7E-28 T 28-03-2018 IPR000362 Fumarate lyase family WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 6.3E-24 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 SUPERFAMILY SSF48557 3 456 1.73E-141 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 Gene3D G3DSA:1.20.200.10 108 375 1.4E-95 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 4.6E-68 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 4.6E-68 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 4.6E-68 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 4.6E-68 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 4.6E-68 T 28-03-2018 WM46_RS21005 2694b0b9a65ab0645848ed06554f9c25 457 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 4.6E-68 T 28-03-2018 WM46_RS20955 e99295b162fd58af9e940a67f3390883 106 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 89 4.2E-40 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 WM46_RS20955 e99295b162fd58af9e940a67f3390883 106 SUPERFAMILY SSF52794 3 99 5.06E-35 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS20955 e99295b162fd58af9e940a67f3390883 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 96 1.8E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS20955 e99295b162fd58af9e940a67f3390883 106 Gene3D G3DSA:3.40.50.2300 3 102 7.5E-41 T 28-03-2018 WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 Gene3D G3DSA:2.40.170.20 195 750 2.3E-93 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 48 - T 28-03-2018 IPR010916 TonB box, conserved site WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 733 750 - T 28-03-2018 IPR010917 TonB-dependent receptor, conserved site WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 181 1.8E-20 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 Pfam PF00593 TonB dependent receptor 271 749 3.8E-64 T 28-03-2018 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 Gene3D G3DSA:2.170.130.10 31 194 4.1E-28 T 28-03-2018 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 79 750 1.4E-188 T 28-03-2018 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 WM46_RS14065 2eeb734f0b891c3da61d73c3e6f5b984 750 SUPERFAMILY SSF56935 69 750 2.62E-142 T 28-03-2018 WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 6 253 1.6E-137 T 28-03-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 Gene3D G3DSA:3.40.50.720 3 43 2.7E-6 T 28-03-2018 WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 Gene3D G3DSA:3.40.50.720 44 253 5.5E-58 T 28-03-2018 WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 SUPERFAMILY SSF51735 9 252 3.38E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS24775 d6e6f653db78ae509432aaefd4b6be0c 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 3.7E-56 T 28-03-2018 WM46_RS10735 21aaf6bee7b1dcc8473184c7ecc025ac 355 SUPERFAMILY SSF81345 15 349 1.01E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS10735 21aaf6bee7b1dcc8473184c7ecc025ac 355 Gene3D G3DSA:1.10.3470.10 19 355 2.1E-70 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS10735 21aaf6bee7b1dcc8473184c7ecc025ac 355 Pfam PF01032 FecCD transport family 36 349 6.9E-84 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS21515 068588b85c2899ad4bf4fd8e2fc41446 245 Pfam PF06251 Capsule biosynthesis GfcC 19 244 4.9E-84 T 28-03-2018 IPR010425 Domain of unknown function DUF1017 WM46_RS20505 17003efe2597e6b779758b9360db44c3 96 SUPERFAMILY SSF47413 39 82 3.58E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS20505 17003efe2597e6b779758b9360db44c3 96 Gene3D G3DSA:1.10.260.40 16 86 8.0E-8 T 28-03-2018 WM46_RS02155 ba5de5d0f3bb72b74d43ead99ad63fb5 149 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 40 142 5.5E-44 T 28-03-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB WM46_RS02155 ba5de5d0f3bb72b74d43ead99ad63fb5 149 PIRSF PIRSF006105 3 149 1.4E-53 T 28-03-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB WM46_RS02155 ba5de5d0f3bb72b74d43ead99ad63fb5 149 Gene3D G3DSA:1.10.1130.10 62 128 1.0E-29 T 28-03-2018 WM46_RS02155 ba5de5d0f3bb72b74d43ead99ad63fb5 149 SUPERFAMILY SSF48695 48 145 1.77E-40 T 28-03-2018 IPR011031 Multihaem cytochrome WM46_RS04140 e5924b30752d64b4daafc2083ae369ca 189 Pfam PF05229 Spore Coat Protein U domain 27 185 8.0E-23 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04140 e5924b30752d64b4daafc2083ae369ca 189 SMART SM00972 127 186 2.3E-10 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04140 e5924b30752d64b4daafc2083ae369ca 189 Gene3D G3DSA:2.60.40.1090 40 189 8.2E-4 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS17475 98f615537815942b22a86925403a8f47 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.942 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17475 98f615537815942b22a86925403a8f47 130 Gene3D G3DSA:3.30.1370.30 1 66 2.5E-25 T 28-03-2018 WM46_RS17475 98f615537815942b22a86925403a8f47 130 Pfam PF00410 Ribosomal protein S8 5 129 4.9E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17475 98f615537815942b22a86925403a8f47 130 SUPERFAMILY SSF56047 5 129 4.97E-46 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS17475 98f615537815942b22a86925403a8f47 130 Gene3D G3DSA:3.30.1490.10 74 129 2.9E-22 T 28-03-2018 WM46_RS17475 98f615537815942b22a86925403a8f47 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 WM46_RS07055 d26d9089eb4e5c5b717c5cbbe91521c5 462 Pfam PF00171 Aldehyde dehydrogenase family 9 457 2.9E-135 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 WM46_RS07055 d26d9089eb4e5c5b717c5cbbe91521c5 462 SUPERFAMILY SSF53720 9 460 2.49E-134 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 WM46_RS07055 d26d9089eb4e5c5b717c5cbbe91521c5 462 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 261 272 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 WM46_RS07055 d26d9089eb4e5c5b717c5cbbe91521c5 462 Gene3D G3DSA:3.40.605.10 3 251 1.6E-68 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 WM46_RS07055 d26d9089eb4e5c5b717c5cbbe91521c5 462 Gene3D G3DSA:3.40.309.10 252 443 3.8E-65 T 28-03-2018 WM46_RS12470 ce174b01bcebcc9548fea71623a13e14 516 SMART SM00052 267 507 3.2E-110 T 28-03-2018 IPR001633 EAL domain WM46_RS12470 ce174b01bcebcc9548fea71623a13e14 516 Gene3D G3DSA:3.20.20.450 269 516 5.0E-82 T 28-03-2018 IPR001633 EAL domain WM46_RS12470 ce174b01bcebcc9548fea71623a13e14 516 Pfam PF00563 EAL domain 274 501 8.4E-67 T 28-03-2018 IPR001633 EAL domain WM46_RS12470 ce174b01bcebcc9548fea71623a13e14 516 Pfam PF12792 CSS motif domain associated with EAL 39 242 3.0E-42 T 28-03-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain WM46_RS12470 ce174b01bcebcc9548fea71623a13e14 516 SUPERFAMILY SSF141868 273 514 3.53E-76 T 28-03-2018 IPR001633 EAL domain WM46_RS18610 ecfbac6ea3ae422d2d3d96e7fbf7e676 463 Pfam PF11471 Maltoporin periplasmic N-terminal extension 1 54 1.2E-14 T 28-03-2018 IPR021570 LamB-type porin N-terminal domain WM46_RS18610 ecfbac6ea3ae422d2d3d96e7fbf7e676 463 SUPERFAMILY SSF56935 101 463 4.76E-8 T 28-03-2018 WM46_RS18610 ecfbac6ea3ae422d2d3d96e7fbf7e676 463 Pfam PF16966 Porin-like glycoporin RafY 104 463 1.2E-169 T 28-03-2018 IPR016963 Glycoporin RafY WM46_RS18610 ecfbac6ea3ae422d2d3d96e7fbf7e676 463 Gene3D G3DSA:1.20.5.340 21 117 1.0E-4 T 28-03-2018 WM46_RS03305 32440b5f31ff686d4dd98a3016050552 119 Gene3D G3DSA:2.40.10.180 6 119 2.1E-23 T 28-03-2018 WM46_RS00625 b6a946e2ae406916ac2a0d76c3bf27cd 128 SUPERFAMILY SSF82649 1 125 2.22E-49 T 28-03-2018 WM46_RS00625 b6a946e2ae406916ac2a0d76c3bf27cd 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 126 2.0E-71 T 28-03-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 WM46_RS00625 b6a946e2ae406916ac2a0d76c3bf27cd 128 Pfam PF01592 NifU-like N terminal domain 2 126 2.2E-57 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 WM46_RS00625 b6a946e2ae406916ac2a0d76c3bf27cd 128 Gene3D G3DSA:3.90.1010.10 1 128 4.0E-53 T 28-03-2018 WM46_RS06170 30887939d959df9107aa59319c334d57 187 SUPERFAMILY SSF160443 87 169 4.18E-10 T 28-03-2018 IPR002625 Smr domain WM46_RS06170 30887939d959df9107aa59319c334d57 187 Pfam PF01713 Smr domain 89 169 1.5E-15 T 28-03-2018 IPR002625 Smr domain WM46_RS06170 30887939d959df9107aa59319c334d57 187 SMART SM00463 85 169 2.3E-14 T 28-03-2018 IPR002625 Smr domain WM46_RS06525 05c2d3f54ed86813bb5d32d7a8081705 42 Pfam PF10617 Protein of unknown function (DUF2474) 4 41 1.4E-16 T 28-03-2018 IPR018895 Protein of unknown function DUF2474 WM46_RS07315 17c672093e4d085f3a6af3b47c7fed12 120 Pfam PF00893 Small Multidrug Resistance protein 3 93 4.6E-26 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 WM46_RS07315 17c672093e4d085f3a6af3b47c7fed12 120 Hamap MF_01598 Spermidine export protein MdtJ [mdtJ]. 1 120 30.228 T 28-03-2018 IPR023740 Spermidine export protein MdtJ GO:0005886|GO:0015606|GO:0015848 WM46_RS07315 17c672093e4d085f3a6af3b47c7fed12 120 SUPERFAMILY SSF103481 7 107 1.96E-17 T 28-03-2018 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 Pfam PF00924 Mechanosensitive ion channel 72 268 9.2E-57 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 SUPERFAMILY SSF82689 181 278 1.57E-32 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 Gene3D G3DSA:2.30.30.60 129 179 9.5E-14 T 28-03-2018 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 Gene3D G3DSA:3.30.70.100 180 273 1.2E-29 T 28-03-2018 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 SUPERFAMILY SSF82861 28 112 3.01E-17 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 143 177 - T 28-03-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 SUPERFAMILY SSF50182 114 179 3.17E-16 T 28-03-2018 IPR010920 LSM domain WM46_RS14895 3d98b756c655e0e5ae7c4b8e97f88fd8 286 Pfam PF05552 Conserved TM helix 15 64 4.2E-14 T 28-03-2018 IPR008910 Conserved TM helix WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 SUPERFAMILY SSF50331 237 355 3.16E-29 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 SUPERFAMILY SSF52540 4 243 3.08E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 Pfam PF08402 TOBE domain 278 348 1.0E-9 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 Gene3D G3DSA:3.40.50.300 2 239 8.8E-67 T 28-03-2018 WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 Gene3D G3DSA:2.40.50.100 240 289 2.9E-11 T 28-03-2018 WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 SMART SM00382 29 326 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 Pfam PF00005 ABC transporter 21 162 8.1E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 Gene3D G3DSA:2.40.50.140 290 341 1.8E-15 T 28-03-2018 WM46_RS18090 dee796896986e5cd9dab991bbd4c5e13 356 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS19745 e60b0873309f5e81441ce530c6740aeb 115 Pfam PF02656 Domain of unknown function (DUF202) 13 79 5.1E-16 T 28-03-2018 IPR003807 Domain of unknown function DUF202 WM46_RS19745 e60b0873309f5e81441ce530c6740aeb 115 Gene3D G3DSA:1.20.1050.50 3 115 4.7E-4 T 28-03-2018 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 Gene3D G3DSA:3.40.190.10 88 175 7.1E-26 T 28-03-2018 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 Pfam PF03466 LysR substrate binding domain 89 289 1.0E-48 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 Gene3D G3DSA:1.10.10.10 3 83 6.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.1E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 SUPERFAMILY SSF53850 90 291 2.04E-46 T 28-03-2018 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 Gene3D G3DSA:3.40.190.10 176 260 1.2E-22 T 28-03-2018 WM46_RS01390 930c2c8f77f89f6b936a3aa18d5ed7ce 297 SUPERFAMILY SSF46785 4 111 6.22E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS12305 d6eb9e1cd0c2c42a97eaee266bc632ec 238 Pfam PF11340 Protein of unknown function (DUF3142) 83 176 1.0E-19 T 28-03-2018 IPR021488 Protein of unknown function DUF3142 WM46_RS12305 d6eb9e1cd0c2c42a97eaee266bc632ec 238 Gene3D G3DSA:3.20.20.80 73 227 2.6E-4 T 28-03-2018 WM46_RS08745 183554434f7f87d651791732355e320a 544 Gene3D G3DSA:1.20.1170.10 2 359 9.6E-5 T 28-03-2018 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 437 456 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 156 180 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 463 484 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 123 143 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 510 534 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 260 282 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 49 71 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 11 34 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 216 234 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 358 380 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 PRINTS PR01005 Flagellar hook-associated protein signature 405 422 2.1E-140 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS08745 183554434f7f87d651791732355e320a 544 Pfam PF00460 Flagella basal body rod protein 5 35 2.0E-5 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 WM46_RS08745 183554434f7f87d651791732355e320a 544 SUPERFAMILY SSF64518 136 542 1.03E-50 T 28-03-2018 WM46_RS08745 183554434f7f87d651791732355e320a 544 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 489 542 8.1E-8 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain WM46_RS08745 183554434f7f87d651791732355e320a 544 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 3 354 1.3E-77 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 WM46_RS10935 6f464d3de6c5fc23d07f5d58d1025b08 214 SMART SM01007 11 190 1.5E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS10935 6f464d3de6c5fc23d07f5d58d1025b08 214 Gene3D G3DSA:3.40.225.10 5 204 3.2E-53 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS10935 6f464d3de6c5fc23d07f5d58d1025b08 214 SUPERFAMILY SSF53639 2 208 1.47E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS10935 6f464d3de6c5fc23d07f5d58d1025b08 214 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 190 3.1E-45 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal WM46_RS13875 9f64d2ace7fe716196ede4f31e065e0d 84 Gene3D G3DSA:2.30.30.400 8 81 2.7E-26 T 28-03-2018 WM46_RS13875 9f64d2ace7fe716196ede4f31e065e0d 84 SUPERFAMILY SSF101744 1 83 9.94E-29 T 28-03-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 WM46_RS13875 9f64d2ace7fe716196ede4f31e065e0d 84 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 7 81 2.1E-27 T 28-03-2018 IPR009778 Modulator of Rho-dependent transcription termination WM46_RS24595 ec08f7fd7dff17b059969bd43dd730d8 166 Gene3D G3DSA:2.60.40.1090 35 166 7.8E-26 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24595 ec08f7fd7dff17b059969bd43dd730d8 166 SUPERFAMILY SSF49401 26 165 8.45E-25 T 28-03-2018 IPR008966 Adhesion domain WM46_RS12300 b9d7247cf94a834b865512660953a5b1 714 Gene3D G3DSA:1.25.40.10 428 710 1.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS12300 b9d7247cf94a834b865512660953a5b1 714 Gene3D G3DSA:1.25.20.10 46 331 0.0043 T 28-03-2018 WM46_RS23410 8d6e568e9f0d13e73ccfbef0bd97f8bf 147 Gene3D G3DSA:3.40.50.10110 1 147 9.7E-51 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 WM46_RS23410 8d6e568e9f0d13e73ccfbef0bd97f8bf 147 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 141 1.3E-37 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 WM46_RS23410 8d6e568e9f0d13e73ccfbef0bd97f8bf 147 SUPERFAMILY SSF102400 1 145 7.19E-46 T 28-03-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 WM46_RS15870 aa420658b375f144c71fcab3d9662a3a 73 ProDom PD056719 YEET C0272 C4574 AEC74 ECS1404 C1284 INTERGENIC-REGION YKFH YPJJ 10 73 1.0E-25 T 28-03-2018 IPR009329 Protein of unknown function DUF987 WM46_RS15870 aa420658b375f144c71fcab3d9662a3a 73 Pfam PF06174 Protein of unknown function (DUF987) 1 65 3.2E-38 T 28-03-2018 IPR009329 Protein of unknown function DUF987 WM46_RS20190 ff18d2c80d224bbc5dcd3e17acfb6a24 359 Pfam PF00534 Glycosyl transferases group 1 175 330 3.3E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS20190 ff18d2c80d224bbc5dcd3e17acfb6a24 359 Gene3D G3DSA:3.40.50.2000 1 176 4.8E-6 T 28-03-2018 WM46_RS20190 ff18d2c80d224bbc5dcd3e17acfb6a24 359 Gene3D G3DSA:3.40.50.2000 177 331 2.5E-28 T 28-03-2018 WM46_RS20190 ff18d2c80d224bbc5dcd3e17acfb6a24 359 SUPERFAMILY SSF53756 2 325 5.5E-52 T 28-03-2018 WM46_RS20190 ff18d2c80d224bbc5dcd3e17acfb6a24 359 Pfam PF13439 Glycosyltransferase Family 4 13 166 5.4E-9 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 WM46_RS05040 d8eb18bbd6af97daa47a7ba54a54ffe7 212 PIRSF PIRSF006324 4 212 4.4E-61 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS05040 d8eb18bbd6af97daa47a7ba54a54ffe7 212 Pfam PF01810 LysE type translocator 18 209 5.5E-53 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 Gene3D G3DSA:2.40.40.10 60 171 1.8E-15 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 Gene3D G3DSA:3.30.70.1070 298 370 5.6E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 83 182 6.8E-29 T 28-03-2018 IPR012997 Rare lipoprotein A WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 SUPERFAMILY SSF50685 83 162 1.4E-6 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 12 171 20.543 T 28-03-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 Pfam PF03330 Lytic transglycolase 81 168 1.4E-19 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 SUPERFAMILY SSF110997 296 366 2.22E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS11400 72150bff5216e54e11cd7dbeb7277ac6 371 Pfam PF05036 Sporulation related domain 296 367 5.2E-15 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS04550 b16ee00cba5f8dbab39acbd7f2fccb3d 181 Gene3D G3DSA:1.10.3600.10 31 137 1.6E-30 T 28-03-2018 IPR009364 Putative bacterial toxin ydaT WM46_RS04550 b16ee00cba5f8dbab39acbd7f2fccb3d 181 Pfam PF06254 Putative bacterial toxin ydaT 73 156 2.1E-35 T 28-03-2018 IPR009364 Putative bacterial toxin ydaT WM46_RS14125 8caca957b24a8ef147acd5223cf87d80 408 Pfam PF01522 Polysaccharide deacetylase 228 365 7.9E-19 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 WM46_RS14125 8caca957b24a8ef147acd5223cf87d80 408 SUPERFAMILY SSF88713 190 378 6.86E-28 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 WM46_RS14125 8caca957b24a8ef147acd5223cf87d80 408 Gene3D G3DSA:3.20.20.370 163 404 1.3E-35 T 28-03-2018 WM46_RS15550 a503040844b0737f907470e94cdf70b4 252 Pfam PF14348 Domain of unknown function (DUF4400) 54 249 4.7E-73 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type WM46_RS15550 a503040844b0737f907470e94cdf70b4 252 TIGRFAM TIGR03747 conj_TIGR03747: integrating conjugative element membrane protein, PFL_4697 family 17 252 2.4E-95 T 28-03-2018 IPR022266 Integrating conjugative element protein, PFL4697-type WM46_RS24890 3a098a0eddf99ca0bfaa07df505e6377 135 Pfam PF10713 Protein of unknown function (DUF2509) 15 132 8.7E-28 T 28-03-2018 IPR019652 Protein of unknown function DUF2509 WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 SUPERFAMILY SSF50331 239 345 3.4E-12 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 Pfam PF12857 TOBE-like domain 289 339 1.2E-6 T 28-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 SUPERFAMILY SSF52540 3 244 6.63E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 Pfam PF00005 ABC transporter 18 164 2.4E-37 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 1.7E-127 T 28-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 Gene3D G3DSA:3.40.50.300 1 254 1.7E-76 T 28-03-2018 WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS01085 72aaec5a5b987e19b726154a1caf67f6 367 SMART SM00382 27 214 2.7E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS11890 94655cf00302cdbad44c54c238e1ff92 218 SUPERFAMILY SSF52218 67 180 1.71E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS11890 94655cf00302cdbad44c54c238e1ff92 218 Pfam PF12682 Flavodoxin 67 190 2.3E-22 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 WM46_RS11890 94655cf00302cdbad44c54c238e1ff92 218 Gene3D G3DSA:3.40.50.360 30 212 6.2E-34 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS21835 8a41029723d024174bc2fcdcbc9b3125 144 Pfam PF00583 Acetyltransferase (GNAT) family 44 133 5.6E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS21835 8a41029723d024174bc2fcdcbc9b3125 144 SUPERFAMILY SSF55729 5 138 5.23E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS21835 8a41029723d024174bc2fcdcbc9b3125 144 Gene3D G3DSA:3.40.630.30 1 144 1.0E-23 T 28-03-2018 WM46_RS05570 f64e236c8ab14bab8a4db76046662beb 269 Pfam PF13371 Tetratricopeptide repeat 187 259 6.1E-26 T 28-03-2018 WM46_RS05570 f64e236c8ab14bab8a4db76046662beb 269 Gene3D G3DSA:1.25.40.10 34 268 3.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS05570 f64e236c8ab14bab8a4db76046662beb 269 Pfam PF13369 Transglutaminase-like superfamily 33 184 1.3E-41 T 28-03-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 9 243 40.44 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 SUPERFAMILY SSF52402 20 208 5.33E-53 T 28-03-2018 WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 48 219 7.7E-52 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 PIRSF PIRSF000857 6 244 8.9E-55 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 21 242 1.8E-102 T 28-03-2018 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8 WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 Gene3D G3DSA:3.40.50.620 2 216 1.8E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS25225 63de3a2fae3fabb8b1871500639d0d84 244 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 33 243 1.5E-95 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 31 112 1.5E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 SUPERFAMILY SSF55604 11 82 3.14E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 Pfam PF02378 Phosphotransferase system, EIIC 113 405 7.9E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 8 461 1.3E-218 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 22 39 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 Pfam PF00367 phosphotransferase system, EIIB 13 40 1.7E-11 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 WM46_RS23275 2b7db3fd02db67c93de70b3e5e05e145 473 Gene3D G3DSA:3.30.1360.60 6 79 1.4E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 WM46_RS09165 869560976fc1943d1c180811f9dfb8b1 235 SMART SM00418 19 98 2.2E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS09165 869560976fc1943d1c180811f9dfb8b1 235 SUPERFAMILY SSF46785 10 98 5.52E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS09165 869560976fc1943d1c180811f9dfb8b1 235 Pfam PF01022 Bacterial regulatory protein, arsR family 26 71 2.3E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 WM46_RS09165 869560976fc1943d1c180811f9dfb8b1 235 Gene3D G3DSA:1.10.10.10 4 106 3.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS18230 7d6d6e58f4a87e9d34a26cddb21a6cd1 349 Pfam PF01594 AI-2E family transporter 14 328 1.4E-76 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like WM46_RS08065 82705005918f7e759ceec326e99e8e87 252 Pfam PF04338 Protein of unknown function, DUF481 48 251 1.3E-57 T 28-03-2018 IPR007433 Protein of unknown function DUF481 WM46_RS04055 407f4cd918cf22987061bab7b7bab3bd 83 Pfam PF10964 Protein of unknown function (DUF2766) 1 78 6.9E-48 T 28-03-2018 IPR020262 Uncharacterised protein family YecJ WM46_RS04055 407f4cd918cf22987061bab7b7bab3bd 83 ProDom PD060536 YECJ YPO1738 1 77 8.0E-36 T 28-03-2018 IPR020262 Uncharacterised protein family YecJ WM46_RS02220 ce4fe09b8281d3826c097245980d36a1 120 PIRSF PIRSF006298 1 118 4.0E-55 T 28-03-2018 IPR016480 Glucose translocase, bactoprenol-linked WM46_RS02220 ce4fe09b8281d3826c097245980d36a1 120 Pfam PF04138 GtrA-like protein 7 116 5.6E-14 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 WM46_RS25620 50d85decab43974941829b4c4e8c3c08 331 Gene3D G3DSA:3.40.190.10 159 326 4.3E-35 T 28-03-2018 WM46_RS25620 50d85decab43974941829b4c4e8c3c08 331 Gene3D G3DSA:3.40.190.10 22 158 5.7E-16 T 28-03-2018 WM46_RS25620 50d85decab43974941829b4c4e8c3c08 331 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 312 4.4E-53 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 WM46_RS25620 50d85decab43974941829b4c4e8c3c08 331 SUPERFAMILY SSF53850 24 329 8.87E-92 T 28-03-2018 WM46_RS15220 83e1a2c640ff3b8adeeb91c282de961b 511 SUPERFAMILY SSF103473 10 202 3.53E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS15220 83e1a2c640ff3b8adeeb91c282de961b 511 SUPERFAMILY SSF103473 256 423 3.53E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS15220 83e1a2c640ff3b8adeeb91c282de961b 511 SUPERFAMILY SSF103473 473 491 3.53E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS15220 83e1a2c640ff3b8adeeb91c282de961b 511 Gene3D G3DSA:1.20.1250.20 7 207 2.4E-20 T 28-03-2018 WM46_RS15220 83e1a2c640ff3b8adeeb91c282de961b 511 Gene3D G3DSA:1.20.1250.20 267 501 7.8E-14 T 28-03-2018 WM46_RS15220 83e1a2c640ff3b8adeeb91c282de961b 511 Pfam PF07690 Major Facilitator Superfamily 22 411 3.3E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS22865 d483d640c180588dde067425104a167d 153 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 133 1.8E-42 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 WM46_RS22865 d483d640c180588dde067425104a167d 153 Gene3D G3DSA:3.40.50.300 1 153 1.9E-52 T 28-03-2018 WM46_RS22865 d483d640c180588dde067425104a167d 153 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 140 8.1E-59 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 WM46_RS22865 d483d640c180588dde067425104a167d 153 SUPERFAMILY SSF52540 29 133 1.46E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS20725 d175ba16833bb0adf6d0ceaf833ccd54 342 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 57 331 9.2E-129 T 28-03-2018 IPR005274 Inner membrane protein YhjD WM46_RS20725 d175ba16833bb0adf6d0ceaf833ccd54 342 PIRSF PIRSF035875 44 333 2.0E-23 T 28-03-2018 IPR017039 Virulence factor BrkB WM46_RS20725 d175ba16833bb0adf6d0ceaf833ccd54 342 Pfam PF03631 Virulence factor BrkB 71 330 2.6E-49 T 28-03-2018 IPR017039 Virulence factor BrkB WM46_RS19560 8c6416d8448773d96559f72feb70e06b 296 Gene3D G3DSA:1.10.3720.10 17 287 1.5E-36 T 28-03-2018 WM46_RS19560 8c6416d8448773d96559f72feb70e06b 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 290 6.7E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS19560 8c6416d8448773d96559f72feb70e06b 296 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 28 292 4.5E-85 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 WM46_RS19560 8c6416d8448773d96559f72feb70e06b 296 SUPERFAMILY SSF161098 35 286 8.76E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS12885 13b3f6f912adc88b02f621904ef9f5eb 213 Gene3D G3DSA:3.40.50.850 2 207 8.7E-34 T 28-03-2018 WM46_RS12885 13b3f6f912adc88b02f621904ef9f5eb 213 Pfam PF00857 Isochorismatase family 12 165 3.7E-23 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS12885 13b3f6f912adc88b02f621904ef9f5eb 213 SUPERFAMILY SSF52499 4 203 2.09E-48 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS17690 e6ab251968d3d4b4a9de80b534bfde9f 695 Pfam PF12805 FUSC-like inner membrane protein yccS 63 330 4.5E-71 T 28-03-2018 IPR032692 Integral membrane protein YccS, N-terminal WM46_RS17690 e6ab251968d3d4b4a9de80b534bfde9f 695 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 12 673 1.1E-249 T 28-03-2018 IPR010020 Integral membrane protein, YccS/YhfK WM46_RS17690 e6ab251968d3d4b4a9de80b534bfde9f 695 Pfam PF13515 Fusaric acid resistance protein-like 377 498 2.5E-20 T 28-03-2018 WM46_RS11000 2b7d326d75cd658e31698ef57c3d78c6 115 PIRSF PIRSF000169 1 115 1.9E-41 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 WM46_RS11000 2b7d326d75cd658e31698ef57c3d78c6 115 Gene3D G3DSA:1.20.1300.10 1 115 5.1E-18 T 28-03-2018 WM46_RS11000 2b7d326d75cd658e31698ef57c3d78c6 115 SUPERFAMILY SSF81343 5 115 1.57E-30 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11000 2b7d326d75cd658e31698ef57c3d78c6 115 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 113 2.4E-36 T 28-03-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 WM46_RS11000 2b7d326d75cd658e31698ef57c3d78c6 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 104 1.6E-6 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS06240 1ddc5132e240d72a05161ee42a18c101 311 SUPERFAMILY SSF52402 17 235 7.12E-55 T 28-03-2018 WM46_RS06240 1ddc5132e240d72a05161ee42a18c101 311 PIRSF PIRSF004976 1 269 1.3E-76 T 28-03-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 WM46_RS06240 1ddc5132e240d72a05161ee42a18c101 311 Gene3D G3DSA:3.40.50.620 6 246 1.1E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS06240 1ddc5132e240d72a05161ee42a18c101 311 Pfam PF01171 PP-loop family 42 205 9.7E-14 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 WM46_RS06240 1ddc5132e240d72a05161ee42a18c101 311 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 10 271 57.729 T 28-03-2018 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 WM46_RS15255 26808e9940586e7624ab5a541952738b 262 Pfam PF01925 Sulfite exporter TauE/SafE 7 260 1.5E-31 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 WM46_RS19710 4945cdb09cd17411cadc10a9c02d2eee 110 Pfam PF07119 Protein of unknown function (DUF1375) 15 77 2.3E-12 T 28-03-2018 IPR010780 Protein of unknown function DUF1375 WM46_RS23005 01b36bd716977ccf270969b097829b02 309 Pfam PF00892 EamA-like transporter family 172 305 3.4E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS23005 01b36bd716977ccf270969b097829b02 309 Pfam PF00892 EamA-like transporter family 17 159 1.2E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS23005 01b36bd716977ccf270969b097829b02 309 SUPERFAMILY SSF103481 205 306 9.15E-8 T 28-03-2018 WM46_RS23005 01b36bd716977ccf270969b097829b02 309 SUPERFAMILY SSF103481 57 161 1.57E-13 T 28-03-2018 WM46_RS13470 416a2ca8f2dcc8a75b160e9caaa7e5f0 76 Pfam PF04971 Bacteriophage P21 holin S 7 68 6.5E-33 T 28-03-2018 IPR007054 Lysis protein S GO:0019835 WM46_RS13470 416a2ca8f2dcc8a75b160e9caaa7e5f0 76 PIRSF PIRSF030786 1 70 2.5E-37 T 28-03-2018 IPR007054 Lysis protein S GO:0019835 WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 SUPERFAMILY SSF51604 106 304 5.63E-52 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 7 306 1.6E-126 T 28-03-2018 WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 Gene3D G3DSA:3.30.390.10 1 109 2.4E-20 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 4 320 23.795 T 28-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 Pfam PF13378 Enolase C-terminal domain-like 122 279 2.2E-17 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 SUPERFAMILY SSF54826 1 97 1.14E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 SMART SM00922 114 209 4.6E-13 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS01865 8bdc9dd80a2db16be599149b393a02b0 320 Gene3D G3DSA:3.20.20.120 110 294 1.6E-40 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS22490 ecb26b4d86d2adfcbbbbb98673e5f6f4 304 Pfam PF00892 EamA-like transporter family 14 145 2.6E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS22490 ecb26b4d86d2adfcbbbbb98673e5f6f4 304 Pfam PF00892 EamA-like transporter family 157 292 9.2E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS22490 ecb26b4d86d2adfcbbbbb98673e5f6f4 304 SUPERFAMILY SSF103481 193 295 4.84E-5 T 28-03-2018 WM46_RS22490 ecb26b4d86d2adfcbbbbb98673e5f6f4 304 SUPERFAMILY SSF103481 45 147 1.29E-13 T 28-03-2018 WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 SMART SM00849 508 689 2.3E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 Pfam PF03772 Competence protein 201 464 1.4E-51 T 28-03-2018 IPR004477 ComEC/Rec2-related protein WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 Gene3D G3DSA:3.60.15.10 493 710 6.0E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 65 718 9.6E-256 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 Pfam PF00753 Metallo-beta-lactamase superfamily 505 687 2.0E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 SUPERFAMILY SSF56281 497 742 4.76E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS09840 3ca7dec3e44b25edaa6947f538786617 754 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 221 404 1.9E-50 T 28-03-2018 IPR004477 ComEC/Rec2-related protein WM46_RS03570 0815726b97432d184a6a2af53c9b5287 189 Gene3D G3DSA:3.40.50.150 2 188 2.8E-26 T 28-03-2018 WM46_RS03570 0815726b97432d184a6a2af53c9b5287 189 SUPERFAMILY SSF53335 3 156 5.84E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS03570 0815726b97432d184a6a2af53c9b5287 189 Pfam PF05175 Methyltransferase small domain 24 103 2.6E-7 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 WM46_RS03570 0815726b97432d184a6a2af53c9b5287 189 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 13 132 7.3E-42 T 28-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 SUPERFAMILY SSF46785 2 109 4.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 Gene3D G3DSA:3.40.190.10 88 176 1.2E-19 T 28-03-2018 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.7E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 Gene3D G3DSA:3.40.190.10 177 259 1.9E-17 T 28-03-2018 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 Pfam PF03466 LysR substrate binding domain 86 288 8.2E-43 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 SUPERFAMILY SSF53850 87 291 1.13E-40 T 28-03-2018 WM46_RS19040 7b5aec3fc1387de76038bb04404ccf2f 317 Gene3D G3DSA:1.10.10.10 1 87 6.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS25345 ab454c26fb94e7094215f7bd4dd96c07 114 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 1 97 9.0E-49 T 28-03-2018 IPR020483 Uncharacterised protein family YgbA WM46_RS25345 ab454c26fb94e7094215f7bd4dd96c07 114 Pfam PF11756 Nitrous oxide-stimulated promoter 4 106 1.5E-39 T 28-03-2018 IPR020483 Uncharacterised protein family YgbA WM46_RS22245 23d74ef9d04a3ba1c2873949713ea5f2 510 Gene3D G3DSA:3.30.450.90 58 197 1.4E-17 T 28-03-2018 WM46_RS22245 23d74ef9d04a3ba1c2873949713ea5f2 510 Gene3D G3DSA:3.40.50.300 200 498 1.1E-31 T 28-03-2018 WM46_RS22245 23d74ef9d04a3ba1c2873949713ea5f2 510 Pfam PF00437 Type II/IV secretion system protein 98 366 3.1E-30 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 WM46_RS22245 23d74ef9d04a3ba1c2873949713ea5f2 510 SUPERFAMILY SSF52540 85 488 1.48E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22245 23d74ef9d04a3ba1c2873949713ea5f2 510 SMART SM00382 227 371 0.0025 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS07190 c72589d5754b241c6fc04cb80a16dc1c 113 ProDom PD073251 YNFB PERIPLASMIC SECRETED ORF9 PRECURSOR SIGNAL SIMILAR ECS2289 EXPORTED ESCHERICHIA 1 113 7.0E-52 T 28-03-2018 IPR009700 Protein of unknown function DUF1283 WM46_RS07190 c72589d5754b241c6fc04cb80a16dc1c 113 Hamap MF_01581 UPF0482 protein YnfB [ynfB]. 2 113 27.377 T 28-03-2018 IPR009700 Protein of unknown function DUF1283 WM46_RS07190 c72589d5754b241c6fc04cb80a16dc1c 113 Pfam PF06932 Protein of unknown function (DUF1283) 32 113 1.1E-41 T 28-03-2018 IPR009700 Protein of unknown function DUF1283 WM46_RS12410 c6bf63ee60742682c4ddbc2f9a1506fd 171 Gene3D G3DSA:1.10.357.10 18 170 7.9E-4 T 28-03-2018 WM46_RS12410 c6bf63ee60742682c4ddbc2f9a1506fd 171 Pfam PF07445 Primosomal replication protein priC 4 168 1.7E-44 T 28-03-2018 IPR010890 Primosomal replication PriB/PriC WM46_RS17555 5cc604f852c2fe7a22870891ea999bab 160 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 75 85 3.7E-16 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS17555 5cc604f852c2fe7a22870891ea999bab 160 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 86 97 3.7E-16 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS17555 5cc604f852c2fe7a22870891ea999bab 160 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 18 35 3.7E-16 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS17555 5cc604f852c2fe7a22870891ea999bab 160 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 98 113 3.7E-16 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial WM46_RS17555 5cc604f852c2fe7a22870891ea999bab 160 Pfam PF01478 Type IV leader peptidase family 10 114 1.2E-21 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 WM46_RS04105 214cd4bdd52fd2dacdd47660f05247d8 116 Gene3D G3DSA:1.10.4000.10 3 102 6.9E-46 T 28-03-2018 WM46_RS04105 214cd4bdd52fd2dacdd47660f05247d8 116 SUPERFAMILY SSF63592 1 98 4.18E-39 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 WM46_RS04105 214cd4bdd52fd2dacdd47660f05247d8 116 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 1 104 27.96 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 WM46_RS04105 214cd4bdd52fd2dacdd47660f05247d8 116 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 9 98 7.0E-46 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 WM46_RS04105 214cd4bdd52fd2dacdd47660f05247d8 116 Pfam PF05247 Flagellar transcriptional activator (FlhD) 1 100 4.2E-40 T 28-03-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 Gene3D G3DSA:2.40.100.10 13 190 2.7E-53 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 SUPERFAMILY SSF50891 26 189 1.46E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 65 82 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 31 188 5.6E-50 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 70 82 1.5E-10 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 44 59 1.5E-10 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS17715 edfebfce0a3bcdbfc0534b76d32161d1 190 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 144 159 1.5E-10 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 WM46_RS08805 1cc35d3a39e2d269d3aa72100488f798 97 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 1 89 4.5E-19 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 WM46_RS08805 1cc35d3a39e2d269d3aa72100488f798 97 Pfam PF04316 Anti-sigma-28 factor, FlgM 40 87 1.5E-10 T 28-03-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal WM46_RS08805 1cc35d3a39e2d269d3aa72100488f798 97 Gene3D G3DSA:1.10.287.1160 59 88 1.3E-10 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 WM46_RS08805 1cc35d3a39e2d269d3aa72100488f798 97 SUPERFAMILY SSF101498 1 88 1.44E-13 T 28-03-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 WM46_RS20745 e0d4cb23c023fd2c4df06911d7bf66fd 182 Gene3D G3DSA:3.40.630.30 1 178 3.7E-36 T 28-03-2018 WM46_RS20745 e0d4cb23c023fd2c4df06911d7bf66fd 182 SUPERFAMILY SSF55729 2 170 8.98E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS20745 e0d4cb23c023fd2c4df06911d7bf66fd 182 Pfam PF13302 Acetyltransferase (GNAT) domain 8 145 1.4E-27 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS11820 99525edae3806315d30a45c9be6895c7 190 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 179 3.4E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS11820 99525edae3806315d30a45c9be6895c7 190 Gene3D G3DSA:1.10.10.10 96 182 6.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11820 99525edae3806315d30a45c9be6895c7 190 SUPERFAMILY SSF46894 127 180 6.12E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS19440 973e9bb9b2d563a06dd145b48ed1e3dd 139 Gene3D G3DSA:3.40.1650.10 1 139 8.0E-41 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS19440 973e9bb9b2d563a06dd145b48ed1e3dd 139 SUPERFAMILY SSF102546 1 139 2.35E-45 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS19440 973e9bb9b2d563a06dd145b48ed1e3dd 139 Pfam PF05025 RbsD / FucU transport protein family 1 138 1.5E-48 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 WM46_RS19440 973e9bb9b2d563a06dd145b48ed1e3dd 139 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 139 33.378 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 WM46_RS00790 4f6bdaee1f9ab7159fbf42ae1d982a66 429 Pfam PF00860 Permease family 16 383 1.0E-107 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS00790 4f6bdaee1f9ab7159fbf42ae1d982a66 429 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 405 4.7E-131 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS00790 4f6bdaee1f9ab7159fbf42ae1d982a66 429 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 329 349 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS24685 7bf24c777b53c92aa7a0448d317190e5 76 Pfam PF06902 Divergent 4Fe-4S mono-cluster 13 76 2.3E-28 T 28-03-2018 IPR010693 Divergent 4Fe-4S mono-cluster WM46_RS16110 97f7054322900e93e7eae3442c1fed48 193 Gene3D G3DSA:3.40.50.1820 2 192 1.1E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS16110 97f7054322900e93e7eae3442c1fed48 193 Pfam PF05728 Uncharacterised protein family (UPF0227) 4 188 2.5E-70 T 28-03-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA WM46_RS16110 97f7054322900e93e7eae3442c1fed48 193 SUPERFAMILY SSF53474 3 188 1.45E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS18190 b2f9bd9d332cbb6c61e794c699d3620c 119 Pfam PF10694 Protein of unknown function (DUF2500) 5 115 1.5E-31 T 28-03-2018 IPR019635 Protein of unknown function DUF2500 WM46_RS10545 f1ad2d07b89a6568361716127bebce06 81 SUPERFAMILY SSF54285 1 81 1.68E-23 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp WM46_RS10545 f1ad2d07b89a6568361716127bebce06 81 Pfam PF02597 ThiS family 4 81 4.9E-22 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 WM46_RS10545 f1ad2d07b89a6568361716127bebce06 81 Gene3D G3DSA:3.10.20.30 1 81 3.0E-20 T 28-03-2018 IPR012675 Beta-grasp domain WM46_RS10545 f1ad2d07b89a6568361716127bebce06 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 81 6.3E-25 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 WM46_RS13610 337e8107ca66acf48c8d6a92bd753e33 97 SMART SM00990 4 84 1.7E-17 T 28-03-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 WM46_RS12400 63df9a152c00c1849ca1dc7d24a4c0c9 183 Pfam PF00156 Phosphoribosyl transferase domain 31 156 1.2E-15 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 WM46_RS12400 63df9a152c00c1849ca1dc7d24a4c0c9 183 Gene3D G3DSA:3.40.50.2020 4 180 1.2E-42 T 28-03-2018 WM46_RS12400 63df9a152c00c1849ca1dc7d24a4c0c9 183 SUPERFAMILY SSF53271 13 180 1.7E-52 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like WM46_RS12400 63df9a152c00c1849ca1dc7d24a4c0c9 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 11 180 38.107 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 WM46_RS12400 63df9a152c00c1849ca1dc7d24a4c0c9 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 11 178 4.2E-73 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 WM46_RS08790 3651fefb448471a4754077212d3973ba 138 Pfam PF00460 Flagella basal body rod protein 9 39 2.3E-12 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 WM46_RS08790 3651fefb448471a4754077212d3973ba 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 28-03-2018 IPR019776 Flagellar basal body rod protein, conserved site WM46_RS08790 3651fefb448471a4754077212d3973ba 138 PIRSF PIRSF002889 1 137 8.2E-44 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 WM46_RS08790 3651fefb448471a4754077212d3973ba 138 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 135 3.1E-47 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 WM46_RS22150 201333e71bdedea22b8bdd5b91228191 242 SMART SM00862 24 101 5.2E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS22150 201333e71bdedea22b8bdd5b91228191 242 Gene3D G3DSA:1.10.10.10 5 108 5.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22150 201333e71bdedea22b8bdd5b91228191 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 100 6.7E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 WM46_RS22150 201333e71bdedea22b8bdd5b91228191 242 SUPERFAMILY SSF46894 19 101 6.52E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS23525 2baeb88a3e34d7118fd353445bb57733 434 SUPERFAMILY SSF51905 9 197 1.9E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23525 2baeb88a3e34d7118fd353445bb57733 434 SUPERFAMILY SSF51905 359 406 1.9E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23525 2baeb88a3e34d7118fd353445bb57733 434 Pfam PF12831 FAD dependent oxidoreductase 18 427 3.5E-104 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23525 2baeb88a3e34d7118fd353445bb57733 434 Gene3D G3DSA:3.50.50.60 16 410 2.0E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 Pfam PF07729 FCD domain 159 286 4.0E-9 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 2.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 2.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 Gene3D G3DSA:1.20.120.530 155 301 4.2E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 Gene3D G3DSA:1.10.10.10 84 154 3.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 Gene3D G3DSA:1.10.10.10 1 71 9.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 60 8.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 SUPERFAMILY SSF46785 3 72 2.62E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 SUPERFAMILY SSF48008 157 294 5.49E-13 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal WM46_RS23940 b96863ea22a99f6587a74bfe1a937f76 301 SMART SM00895 159 287 1.2E-9 T 28-03-2018 IPR011711 GntR, C-terminal WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 SUPERFAMILY SSF51126 3 367 8.53E-79 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 Pfam PF00295 Glycosyl hydrolases family 28 93 313 5.5E-31 T 28-03-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 Gene3D G3DSA:2.160.20.10 2 433 1.7E-82 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 Pfam PF12708 Pectate lyase superfamily protein 6 62 1.0E-8 T 28-03-2018 IPR024535 Pectate lyase superfamily protein WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 SMART SM00710 94 134 3600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 SMART SM00710 241 261 3000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 SMART SM00710 207 228 550.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 SMART SM00710 181 206 0.21 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS14160 30434c7f7de4082a800abce9dc668aac 434 SMART SM00710 267 288 930.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat WM46_RS02880 c4408e08ae4d409203f0f7271c00f695 426 Pfam PF04230 Polysaccharide pyruvyl transferase 13 356 3.3E-40 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase WM46_RS02880 c4408e08ae4d409203f0f7271c00f695 426 TIGRFAM TIGR04006 wcaK: colanic acid biosynthesis pyruvyl transferase WcaK 1 426 3.5E-278 T 28-03-2018 IPR023918 Colanic acid biosynthesis, pyruvyl transferase, WcaK WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 Pfam PF00534 Glycosyl transferases group 1 213 383 1.3E-40 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 Gene3D G3DSA:3.40.50.2000 13 216 2.0E-4 T 28-03-2018 WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 Gene3D G3DSA:3.40.50.2000 217 391 2.2E-37 T 28-03-2018 WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 SUPERFAMILY SSF53756 14 44 2.15E-59 T 28-03-2018 WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 SUPERFAMILY SSF53756 94 404 2.15E-59 T 28-03-2018 WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 TIGRFAM TIGR04005 wcaL: colanic acid biosynthesis glycosyltransferase WcaL 1 406 2.5E-262 T 28-03-2018 IPR023884 Colanic acid biosynthesis, glycosyl transferase, WcaL WM46_RS02885 2c3fe727327545c561c9975a8c996124 406 Pfam PF13439 Glycosyltransferase Family 4 15 210 2.6E-7 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 WM46_RS10435 cc01d5fbf1b4a32df557566e575dbbe6 86 Pfam PF07338 Protein of unknown function (DUF1471) 37 86 5.1E-17 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS10435 cc01d5fbf1b4a32df557566e575dbbe6 86 Gene3D G3DSA:3.30.1660.10 22 86 2.9E-20 T 28-03-2018 IPR025543 Dodecin-like WM46_RS10435 cc01d5fbf1b4a32df557566e575dbbe6 86 SUPERFAMILY SSF159871 3 86 1.14E-22 T 28-03-2018 IPR010854 Domain of unknown function DUF1471 WM46_RS04935 749b044eddfc09a103e933ca0c31abbf 206 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 19 203 25.84 T 28-03-2018 IPR022929 Putative manganese efflux pump MntP WM46_RS04935 749b044eddfc09a103e933ca0c31abbf 206 Pfam PF02659 Putative manganese efflux pump 49 200 1.3E-53 T 28-03-2018 IPR003810 Putative manganese efflux pump WM46_RS06285 293e3c41ad860da249f66b7480119dd7 140 Pfam PF03724 META domain 28 129 1.7E-23 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ WM46_RS04075 e4852012caa45705fb38a0d1cf48718f 329 SUPERFAMILY SSF53822 26 325 5.3E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS04075 e4852012caa45705fb38a0d1cf48718f 329 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 26 319 1.8E-93 T 28-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain WM46_RS04075 e4852012caa45705fb38a0d1cf48718f 329 Gene3D G3DSA:3.40.50.2300 13 147 3.9E-12 T 28-03-2018 WM46_RS04075 e4852012caa45705fb38a0d1cf48718f 329 Gene3D G3DSA:3.40.50.2300 148 293 9.6E-17 T 28-03-2018 WM46_RS04075 e4852012caa45705fb38a0d1cf48718f 329 PIRSF PIRSF002816 1 326 4.9E-152 T 28-03-2018 IPR026266 L-arabinose-binding periplasmic protein GO:0042882 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 ProSitePatterns PS01087 Radical activating enzymes signature. 35 56 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 Gene3D G3DSA:3.20.20.70 10 291 3.6E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 Pfam PF04055 Radical SAM superfamily 41 223 2.0E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 Pfam PF13353 4Fe-4S single cluster domain 34 147 5.5E-11 T 28-03-2018 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 PIRSF PIRSF000371 13 82 1.3E-26 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 PIRSF PIRSF000371 70 292 3.0E-69 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 SUPERFAMILY SSF102114 99 288 4.32E-14 T 28-03-2018 WM46_RS20965 5d77731845bd06cd3f13e975f4bf1c37 292 SUPERFAMILY SSF102114 35 67 4.32E-14 T 28-03-2018 WM46_RS03390 bf72d1e132f50573f04931afb9a11228 146 Gene3D G3DSA:4.10.1070.10 43 138 1.9E-21 T 28-03-2018 WM46_RS03390 bf72d1e132f50573f04931afb9a11228 146 SUPERFAMILY SSF88874 14 145 1.27E-25 T 28-03-2018 WM46_RS03390 bf72d1e132f50573f04931afb9a11228 146 Gene3D G3DSA:3.90.1340.10 4 42 2.9E-5 T 28-03-2018 IPR011083 Phage tail collar domain WM46_RS23145 a226a9dfcdafca8f865462e89cad5ce2 318 SUPERFAMILY SSF53822 23 310 2.52E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS23145 a226a9dfcdafca8f865462e89cad5ce2 318 Pfam PF13407 Periplasmic binding protein domain 26 274 4.1E-44 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS23145 a226a9dfcdafca8f865462e89cad5ce2 318 Gene3D G3DSA:3.40.50.2300 142 301 3.6E-31 T 28-03-2018 WM46_RS23145 a226a9dfcdafca8f865462e89cad5ce2 318 Gene3D G3DSA:3.40.50.2300 18 141 2.5E-21 T 28-03-2018 WM46_RS04845 7d6cc9dbbc78d9360751430b3a281744 63 Pfam PF07358 Protein of unknown function (DUF1482) 1 57 2.4E-33 T 28-03-2018 IPR009954 Protein of unknown function DUF1482 WM46_RS24845 0f6fbe4742c23cc8f3cc7ce344276703 237 Pfam PF03741 Integral membrane protein TerC family 17 203 1.3E-51 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 WM46_RS14850 edbd93bfb9f5173c72cd269725c572f8 157 Pfam PF05981 CreA protein 24 155 1.7E-57 T 28-03-2018 IPR010292 Uncharacterised protein family CreA WM46_RS14850 edbd93bfb9f5173c72cd269725c572f8 157 PIRSF PIRSF003174 1 157 2.9E-69 T 28-03-2018 IPR010292 Uncharacterised protein family CreA WM46_RS12675 580b068695163acbc2889bba1b39ad16 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 25 204 1.7E-88 T 28-03-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 WM46_RS12675 580b068695163acbc2889bba1b39ad16 204 Gene3D G3DSA:1.20.120.80 19 204 4.5E-53 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12675 580b068695163acbc2889bba1b39ad16 204 SUPERFAMILY SSF81452 12 202 1.83E-59 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS12675 580b068695163acbc2889bba1b39ad16 204 Pfam PF00510 Cytochrome c oxidase subunit III 15 202 1.4E-15 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 WM46_RS15270 1eaf01ae6990e04afd81e561683d65ef 310 Gene3D G3DSA:1.10.3530.10 31 207 1.6E-68 T 28-03-2018 IPR023136 Api92-like domain WM46_RS15270 1eaf01ae6990e04afd81e561683d65ef 310 SUPERFAMILY SSF160940 3 278 6.28E-121 T 28-03-2018 WM46_RS15270 1eaf01ae6990e04afd81e561683d65ef 310 Pfam PF06924 Protein of unknown function (DUF1281) 9 141 2.5E-54 T 28-03-2018 IPR009694 Protein of unknown function DUF1281 WM46_RS23680 0a522f0d0c65309e325c8641a704527e 349 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 301 2.9E-46 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS23680 0a522f0d0c65309e325c8641a704527e 349 Gene3D G3DSA:1.10.3470.10 25 307 7.4E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS08485 c173afe8639bf832c36738adea0b2a63 213 Pfam PF04356 Protein of unknown function (DUF489) 7 199 2.8E-74 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 WM46_RS08485 c173afe8639bf832c36738adea0b2a63 213 SUPERFAMILY SSF101322 2 210 3.14E-81 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 WM46_RS08485 c173afe8639bf832c36738adea0b2a63 213 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 207 36.439 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 WM46_RS08485 c173afe8639bf832c36738adea0b2a63 213 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 205 2.0E-95 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 WM46_RS08485 c173afe8639bf832c36738adea0b2a63 213 Gene3D G3DSA:1.10.3890.10 4 207 3.0E-79 T 28-03-2018 IPR007451 Uncharacterised protein family UPF0274 WM46_RS14000 28eaf294829e5f8330be2bb473e89ddf 128 ProDom PD080106 UPF0325 YAEH STRUCTURAL ECA1027 VV11856 YPTB3007 PBPRA2971 VV2560 VF1965 VC2264 1 125 3.0E-66 T 28-03-2018 IPR020911 Uncharacterised protein family UPF0325 WM46_RS14000 28eaf294829e5f8330be2bb473e89ddf 128 Hamap MF_01519 UPF0325 protein YaeH [yaeH]. 1 126 32.85 T 28-03-2018 IPR020911 Uncharacterised protein family UPF0325 WM46_RS14000 28eaf294829e5f8330be2bb473e89ddf 128 Pfam PF11944 Protein of unknown function (DUF3461) 1 125 1.5E-55 T 28-03-2018 IPR020911 Uncharacterised protein family UPF0325 WM46_RS13750 e9541b073f813155eec6f6035b495b85 240 Gene3D G3DSA:3.40.50.150 21 210 2.2E-18 T 28-03-2018 WM46_RS13750 e9541b073f813155eec6f6035b495b85 240 SUPERFAMILY SSF53335 55 207 2.07E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS13750 e9541b073f813155eec6f6035b495b85 240 Pfam PF08241 Methyltransferase domain 72 125 3.2E-11 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 191 46.199 T 28-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 Gene3D G3DSA:3.30.300.130 102 187 1.7E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 2 191 2.5E-100 T 28-03-2018 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 SUPERFAMILY SSF117916 95 184 5.89E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 Gene3D G3DSA:2.60.300.12 1 101 1.2E-15 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 119 177 2.0E-28 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 99 9.2E-13 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 SUPERFAMILY SSF89360 1 97 2.16E-20 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 WM46_RS17905 aff9812180f67b9abd5fa1f603151469 191 Pfam PF01106 NifU-like domain 111 177 2.6E-20 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 WM46_RS08175 7c42b0d02608b9ecdcdecab1e9b9d580 322 PIRSF PIRSF017020 1 322 7.2E-113 T 28-03-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 WM46_RS08175 7c42b0d02608b9ecdcdecab1e9b9d580 322 Gene3D G3DSA:3.40.630.10 42 297 1.0E-31 T 28-03-2018 WM46_RS08175 7c42b0d02608b9ecdcdecab1e9b9d580 322 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 45 319 3.4E-67 T 28-03-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 WM46_RS08175 7c42b0d02608b9ecdcdecab1e9b9d580 322 SUPERFAMILY SSF53187 1 319 5.29E-86 T 28-03-2018 WM46_RS08175 7c42b0d02608b9ecdcdecab1e9b9d580 322 Hamap MF_00767 Succinylglutamate desuccinylase [astE]. 1 322 148.777 T 28-03-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 WM46_RS08175 7c42b0d02608b9ecdcdecab1e9b9d580 322 TIGRFAM TIGR03242 arg_catab_astE: succinylglutamate desuccinylase 3 318 2.7E-132 T 28-03-2018 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96 WM46_RS08615 34c804af3b5cf520aebed8895c59e949 274 Gene3D G3DSA:1.10.510.10 129 226 2.4E-13 T 28-03-2018 WM46_RS08615 34c804af3b5cf520aebed8895c59e949 274 Hamap MF_01604 Thiamine kinase [thiK]. 3 270 37.805 T 28-03-2018 IPR014093 Thiamine kinase GO:0006772|GO:0016310|GO:0019165 KEGG: 00730+2.7.1.89|MetaCyc: PWY-6896 WM46_RS08615 34c804af3b5cf520aebed8895c59e949 274 SUPERFAMILY SSF56112 13 257 5.83E-24 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS08615 34c804af3b5cf520aebed8895c59e949 274 Pfam PF01636 Phosphotransferase enzyme family 29 218 2.9E-13 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase WM46_RS01875 ffb07a4ac28a00795587a18a5ea56c75 87 ProDom PD028730 PMRD RESISTANCE POLYMYXIN B ANTIBIOTIC 1 80 2.0E-24 T 28-03-2018 IPR020146 Signal transduction protein PmrD WM46_RS01875 ffb07a4ac28a00795587a18a5ea56c75 87 Pfam PF11183 Polymyxin resistance protein PmrD 1 80 1.7E-30 T 28-03-2018 WM46_RS18185 40f80bc449847fbe9f40f22b190eb473 89 Pfam PF06611 Protein of unknown function (DUF1145) 1 58 1.8E-26 T 28-03-2018 IPR009525 Protein of unknown function DUF1145 WM46_RS12175 508974e2ad08ff2a10e643effd3efca1 395 SUPERFAMILY SSF56349 99 380 7.3E-62 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS12175 508974e2ad08ff2a10e643effd3efca1 395 Gene3D G3DSA:1.10.443.10 204 385 1.4E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS12175 508974e2ad08ff2a10e643effd3efca1 395 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 100 147 7.8E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS12175 508974e2ad08ff2a10e643effd3efca1 395 Gene3D G3DSA:1.10.150.130 88 203 4.4E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal WM46_RS12175 508974e2ad08ff2a10e643effd3efca1 395 Pfam PF00589 Phage integrase family 207 370 5.1E-24 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS12175 508974e2ad08ff2a10e643effd3efca1 395 Pfam PF13356 Arm DNA-binding domain 3 87 2.0E-19 T 28-03-2018 IPR025166 Integrase, DNA-binding domain WM46_RS15020 b912861818a1a21cd91d1f17daadcb34 43 ProDom PD050163 YQGB INNER MEMBRANE STY3241 1 42 4.0E-14 T 28-03-2018 IPR020196 Uncharacterised protein family YqgB WM46_RS15020 b912861818a1a21cd91d1f17daadcb34 43 Pfam PF11036 Virulence promoting factor 1 43 1.1E-28 T 28-03-2018 IPR020196 Uncharacterised protein family YqgB WM46_RS03000 bf9fa6ac77b2bdb1bc2ed70ad0c1d860 327 Gene3D G3DSA:3.30.1890.10 52 222 7.2E-38 T 28-03-2018 WM46_RS03000 bf9fa6ac77b2bdb1bc2ed70ad0c1d860 327 Gene3D G3DSA:3.30.1890.10 223 294 2.6E-11 T 28-03-2018 WM46_RS03000 bf9fa6ac77b2bdb1bc2ed70ad0c1d860 327 Pfam PF02706 Chain length determinant protein 16 122 5.9E-22 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 WM46_RS03000 bf9fa6ac77b2bdb1bc2ed70ad0c1d860 327 SUPERFAMILY SSF160355 54 292 7.98E-66 T 28-03-2018 WM46_RS11895 93aa405e3e7ca5336d5322fa8fb0d50d 216 Pfam PF14358 Domain of unknown function (DUF4405) 58 117 2.9E-8 T 28-03-2018 IPR025517 Domain of unknown function DUF4405 WM46_RS12650 ca78322fc7ef8d74d6cdcda840ab5dfc 192 Pfam PF08139 Prokaryotic membrane lipoprotein lipid attachment site 1 19 7.9E-7 T 28-03-2018 IPR012640 Membrane lipoprotein, lipid attachment site WM46_RS12650 ca78322fc7ef8d74d6cdcda840ab5dfc 192 Pfam PF03923 Uncharacterized lipoprotein 29 188 1.5E-52 T 28-03-2018 IPR005619 Uncharacterised protein family, YajG WM46_RS06445 2f6e7286e9e3209be3f7fac70b46afd0 210 Gene3D G3DSA:3.20.20.70 1 209 6.5E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS06445 2f6e7286e9e3209be3f7fac70b46afd0 210 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS06445 2f6e7286e9e3209be3f7fac70b46afd0 210 SUPERFAMILY SSF51366 1 207 5.12E-43 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 WM46_RS06445 2f6e7286e9e3209be3f7fac70b46afd0 210 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS06445 2f6e7286e9e3209be3f7fac70b46afd0 210 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 195 3.0E-66 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 WM46_RS03655 056b137c1cbac9ee1e725c115dddf2b4 484 TIGRFAM TIGR00797 matE: MATE efflux family protein 37 441 1.2E-66 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS03655 056b137c1cbac9ee1e725c115dddf2b4 484 Pfam PF01554 MatE 267 428 3.0E-19 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS03655 056b137c1cbac9ee1e725c115dddf2b4 484 Pfam PF01554 MatE 37 197 9.9E-35 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS03655 056b137c1cbac9ee1e725c115dddf2b4 484 PIRSF PIRSF006603 19 475 3.6E-69 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS01160 1ad2609d84451d9f0531de731d8f1d77 72 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 68 1.0E-24 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor WM46_RS01160 1ad2609d84451d9f0531de731d8f1d77 72 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 68 4.7E-29 T 28-03-2018 IPR024530 Putative quorum-sensing-regulated virulence factor WM46_RS14245 9aa4a5b253368a7ae2790fe0efd705b0 263 Pfam PF11453 Protein of unknown function (DUF2950) 20 262 1.3E-79 T 28-03-2018 IPR021556 Protein of unknown function DUF2950 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 9.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-13 T 28-03-2018 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.1E-13 T 28-03-2018 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 1.1E-13 T 28-03-2018 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.1E-13 T 28-03-2018 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 SUPERFAMILY SSF51905 2 323 8.91E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 Gene3D G3DSA:3.50.50.60 147 378 1.0E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 Gene3D G3DSA:3.50.50.60 2 146 2.4E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 2.7E-7 T 28-03-2018 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.7E-7 T 28-03-2018 WM46_RS20785 9b3a22aefad2b22ff5156ec0630af5d6 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 2.7E-7 T 28-03-2018 WM46_RS21745 e6edd6cc1cd7c0bf7b1e8faccf472a80 229 Pfam PF04172 LrgB-like family 14 226 1.3E-67 T 28-03-2018 IPR007300 CidB/LrgB family WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 Pfam PF08013 Tagatose 6 phosphate kinase 4 424 3.1E-202 T 28-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 SUPERFAMILY SSF51569 4 423 1.08E-170 T 28-03-2018 WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 Hamap MF_01295 D-tagatose-1,6-bisphosphate aldolase subunit KbaZ [kbaZ]. 1 426 84.144 T 28-03-2018 IPR023435 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit KbaZ WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 PIRSF PIRSF009264 1 429 1.3E-206 T 28-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 Gene3D G3DSA:1.10.400.20 295 408 1.3E-47 T 28-03-2018 WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 TIGRFAM TIGR02810 agaZ_gatZ: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit 6 424 3.6E-213 T 28-03-2018 IPR012062 D-tagatose-bisphosphate aldolase, non-catalytic subunit GatZ/KbaZ GO:0019402 WM46_RS16590 f1a9a23bb2b6528330331d0c7809a0fd 431 Gene3D G3DSA:3.20.20.70 4 294 5.4E-73 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS22080 8e6fdb352ebe43a1ca403dc50fc8af45 219 SUPERFAMILY SSF46894 146 213 2.99E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS15975 861daa9c23724c10b59a307ce67bf712 164 Pfam PF03350 Uncharacterized protein family, UPF0114 9 125 2.5E-35 T 28-03-2018 IPR005134 Uncharacterised protein family UPF0114 WM46_RS15975 861daa9c23724c10b59a307ce67bf712 164 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 1 163 3.8E-80 T 28-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria WM46_RS15975 861daa9c23724c10b59a307ce67bf712 164 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 164 92.909 T 28-03-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria WM46_RS23665 e081f86ed8093d5038f9342d722cad06 291 Pfam PF01791 DeoC/LacD family aldolase 52 258 9.9E-18 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS23665 e081f86ed8093d5038f9342d722cad06 291 SUPERFAMILY SSF51569 35 274 1.14E-64 T 28-03-2018 WM46_RS23665 e081f86ed8093d5038f9342d722cad06 291 Gene3D G3DSA:3.20.20.70 1 291 5.7E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS23665 e081f86ed8093d5038f9342d722cad06 291 PIRSF PIRSF038992 31 289 1.8E-82 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS23665 e081f86ed8093d5038f9342d722cad06 291 SMART SM01133 51 259 6.3E-29 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS23665 e081f86ed8093d5038f9342d722cad06 291 Hamap MF_02052 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [lsrF]. 1 291 75.076 T 28-03-2018 IPR033673 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase GO:0016747 KEGG: 00600+2.3.1.24 WM46_RS00980 54eb10272434f3e98c14f901d14c2a01 95 Gene3D G3DSA:2.40.50.220 2 95 1.5E-32 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS00980 54eb10272434f3e98c14f901d14c2a01 95 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 83 1.8E-29 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS00980 54eb10272434f3e98c14f901d14c2a01 95 SUPERFAMILY SSF159133 1 94 1.44E-30 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS00980 54eb10272434f3e98c14f901d14c2a01 95 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 11 83 1.0E-35 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS13065 0e3e2ce8b11bcd0cf0dbb1d0291bc6ee 283 SUPERFAMILY SSF51197 5 281 1.1E-98 T 28-03-2018 WM46_RS13065 0e3e2ce8b11bcd0cf0dbb1d0291bc6ee 283 Gene3D G3DSA:3.60.130.10 1 283 1.8E-84 T 28-03-2018 WM46_RS13065 0e3e2ce8b11bcd0cf0dbb1d0291bc6ee 283 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 7 272 6.7E-67 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 WM46_RS16895 32b423dc7cf1060758a72a401d87d899 260 Pfam PF02405 Permease MlaE 44 256 1.1E-72 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 WM46_RS16895 32b423dc7cf1060758a72a401d87d899 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 258 2.8E-106 T 28-03-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria WM46_RS08870 e28d098aeca0ba4c27277602933a6b52 37 ProDom PD049682 YCEO INNER MEMBRANE STY1197 1 37 1.0E-9 T 28-03-2018 IPR024494 Protein of unknown function DUF2770 WM46_RS08870 e28d098aeca0ba4c27277602933a6b52 37 Pfam PF10968 Protein of unknown function (DUF2770) 1 36 2.5E-18 T 28-03-2018 IPR024494 Protein of unknown function DUF2770 WM46_RS23320 2ce58f817f22b1b37d9742c6396af87f 38 Pfam PF08052 PyrBI operon leader peptide 6 37 4.2E-24 T 28-03-2018 IPR012602 PyrBI operon leader peptide GO:0019856 WM46_RS07835 dea8298b3181ad6ca3dfe1cc72b0ab0a 423 Pfam PF01458 Uncharacterized protein family (UPF0051) 170 393 2.1E-69 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 WM46_RS07835 dea8298b3181ad6ca3dfe1cc72b0ab0a 423 SUPERFAMILY SSF101960 11 420 3.79E-113 T 28-03-2018 WM46_RS07835 dea8298b3181ad6ca3dfe1cc72b0ab0a 423 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 133 409 1.8E-87 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 SUPERFAMILY SSF46785 5 88 4.45E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 1.6E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 Gene3D G3DSA:3.40.190.10 86 180 1.9E-14 T 28-03-2018 WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 Pfam PF03466 LysR substrate binding domain 89 291 1.6E-25 T 28-03-2018 IPR005119 LysR, substrate-binding WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 Gene3D G3DSA:3.40.190.10 181 258 6.2E-7 T 28-03-2018 WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 SUPERFAMILY SSF53850 90 292 3.86E-28 T 28-03-2018 WM46_RS03055 e8255128d8472bfaf3c42501391651bd 309 Gene3D G3DSA:1.10.10.10 5 85 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01915 f9e86317d4fee6c45a7b464f10d5ada2 201 Gene3D G3DSA:3.40.50.1240 49 191 2.3E-17 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS01915 f9e86317d4fee6c45a7b464f10d5ada2 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 57 129 1.7E-7 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 WM46_RS01915 f9e86317d4fee6c45a7b464f10d5ada2 201 SUPERFAMILY SSF53254 57 187 2.75E-17 T 28-03-2018 IPR029033 Histidine phosphatase superfamily WM46_RS15540 6d9a46984efa186452f161dbea15216e 123 Gene3D G3DSA:1.10.10.10 4 122 2.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15540 6d9a46984efa186452f161dbea15216e 123 Pfam PF01638 HxlR-like helix-turn-helix 20 107 2.1E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type WM46_RS15540 6d9a46984efa186452f161dbea15216e 123 SUPERFAMILY SSF46785 6 118 4.06E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS02245 5eebc7a018b013c2a3b2ace78bba3060 94 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 2 94 28.098 T 28-03-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM46_RS02245 5eebc7a018b013c2a3b2ace78bba3060 94 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 93 6.0E-42 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM46_RS02245 5eebc7a018b013c2a3b2ace78bba3060 94 Gene3D G3DSA:2.40.240.10 1 94 7.8E-31 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS02245 5eebc7a018b013c2a3b2ace78bba3060 94 SUPERFAMILY SSF50715 1 93 1.29E-30 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 WM46_RS02245 5eebc7a018b013c2a3b2ace78bba3060 94 Pfam PF01386 Ribosomal L25p family 4 91 7.4E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 WM46_RS14885 86ef52e7249d236ea05ca46eeb33e26d 246 Pfam PF04402 Protein of unknown function (DUF541) 30 230 1.9E-44 T 28-03-2018 IPR007497 Protein of unknown function DUF541 WM46_RS25495 1e6af8a9662ab6813482811e373c6433 120 SUPERFAMILY SSF141530 4 118 3.01E-36 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS25495 1e6af8a9662ab6813482811e373c6433 120 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 6 118 3.0E-53 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS25495 1e6af8a9662ab6813482811e373c6433 120 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 113 1.0E-38 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS25495 1e6af8a9662ab6813482811e373c6433 120 Gene3D G3DSA:2.40.33.40 3 118 6.5E-40 T 28-03-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS12845 807af4e2ee20581dd1045c64737a3220 95 SUPERFAMILY SSF52794 4 88 5.89E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS12845 807af4e2ee20581dd1045c64737a3220 95 Gene3D G3DSA:3.40.50.2300 2 92 1.5E-14 T 28-03-2018 WM46_RS12845 807af4e2ee20581dd1045c64737a3220 95 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 71 5.5E-14 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS22690 968e4f9c1c796b060af796ac840ca567 191 Gene3D G3DSA:1.10.10.60 2 52 5.7E-7 T 28-03-2018 WM46_RS22690 968e4f9c1c796b060af796ac840ca567 191 Gene3D G3DSA:1.10.357.10 53 180 2.5E-15 T 28-03-2018 WM46_RS22690 968e4f9c1c796b060af796ac840ca567 191 SUPERFAMILY SSF48498 75 179 2.29E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS22690 968e4f9c1c796b060af796ac840ca567 191 SUPERFAMILY SSF46689 3 60 1.49E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS05385 72c7149dbf0479d78e338e786cd6cab8 124 Pfam PF01381 Helix-turn-helix 17 71 9.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS05385 72c7149dbf0479d78e338e786cd6cab8 124 Gene3D G3DSA:1.10.260.40 4 124 4.4E-20 T 28-03-2018 WM46_RS05385 72c7149dbf0479d78e338e786cd6cab8 124 SMART SM00530 16 71 4.5E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 WM46_RS05385 72c7149dbf0479d78e338e786cd6cab8 124 SUPERFAMILY SSF47413 6 79 9.92E-21 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 1.7E-15 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.7E-15 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 1.7E-15 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.7E-15 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 SUPERFAMILY SSF51905 7 107 2.59E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 SUPERFAMILY SSF51905 225 352 2.59E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 Gene3D G3DSA:3.50.50.60 5 159 5.8E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 3.2E-8 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 3.2E-8 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.2E-8 T 28-03-2018 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 Gene3D G3DSA:3.50.50.60 168 370 9.6E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS08595 0214d946bb7649acc125a6335223364a 434 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 338 2.7E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS21260 fbf91e32daee44c77f6267789832f01d 223 Hamap MF_00801 Endonuclease V [nfi]. 2 216 35.026 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 WM46_RS21260 fbf91e32daee44c77f6267789832f01d 223 Pfam PF04493 Endonuclease V 12 206 4.7E-72 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 WM46_RS00310 4447522f1bb316fcdf10d49f682cb73a 107 Pfam PF10043 Predicted periplasmic lipoprotein (DUF2279) 24 100 1.1E-9 T 28-03-2018 IPR018736 Protein of unknown function DUF2279, periplasmic lipoprotein WM46_RS00310 4447522f1bb316fcdf10d49f682cb73a 107 PIRSF PIRSF034456 1 106 4.2E-55 T 28-03-2018 IPR017028 Uncharacterised conserved protein UCP034456 WM46_RS12450 41d28b490c8466e375210fae5b9de0c5 72 Pfam PF05321 Haemolysin expression modulating protein 13 69 1.5E-33 T 28-03-2018 IPR007985 Haemolysin expression modulating, HHA WM46_RS12450 41d28b490c8466e375210fae5b9de0c5 72 SUPERFAMILY SSF68989 2 72 1.2E-31 T 28-03-2018 IPR007985 Haemolysin expression modulating, HHA WM46_RS12450 41d28b490c8466e375210fae5b9de0c5 72 Gene3D G3DSA:1.20.1280.40 6 71 2.6E-34 T 28-03-2018 IPR007985 Haemolysin expression modulating, HHA WM46_RS03470 c1fa5435962bd01a5d6e6f6b21be86ed 91 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 11 87 3.0E-16 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS03470 c1fa5435962bd01a5d6e6f6b21be86ed 91 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 87 2.2E-30 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS03470 c1fa5435962bd01a5d6e6f6b21be86ed 91 Gene3D G3DSA:2.40.50.220 1 91 2.9E-31 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS03470 c1fa5435962bd01a5d6e6f6b21be86ed 91 SUPERFAMILY SSF159133 1 89 8.37E-27 T 28-03-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 SUPERFAMILY SSF46785 3 141 2.55E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 3.1E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 3.1E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 3.1E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 3.1E-27 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 Pfam PF01047 MarR family 31 89 1.3E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 Hamap MF_01819 Transcriptional regulator SlyA [slyA]. 3 145 42.665 T 28-03-2018 IPR023071 Transcriptional regulator, SlyA WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 Gene3D G3DSA:1.10.10.10 3 146 4.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS07510 3887f66531f74f0e5fe80273061d56e7 146 SMART SM00347 24 125 5.5E-31 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 Gene3D G3DSA:3.50.50.60 242 354 7.9E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 Gene3D G3DSA:3.50.50.60 5 231 1.4E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 Pfam PF01494 FAD binding domain 5 346 5.0E-26 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 SUPERFAMILY SSF51905 7 175 1.83E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 SUPERFAMILY SSF51905 272 360 1.83E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.4E-17 T 28-03-2018 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 3.4E-17 T 28-03-2018 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.4E-17 T 28-03-2018 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.4E-17 T 28-03-2018 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 350 3.4E-17 T 28-03-2018 WM46_RS02525 abeedd3f928cd9995d2a5e319aa3c738 397 SUPERFAMILY SSF54373 179 277 4.32E-14 T 28-03-2018 WM46_RS02230 c85aaca6eab848ed097406c8b4ff0b8c 586 SUPERFAMILY SSF53649 257 579 1.44E-54 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS02230 c85aaca6eab848ed097406c8b4ff0b8c 586 PIRSF PIRSF004950 6 586 6.5E-227 T 28-03-2018 IPR012159 Inner membrane protein YejM WM46_RS02230 c85aaca6eab848ed097406c8b4ff0b8c 586 Pfam PF00884 Sulfatase 260 500 9.1E-31 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS02230 c85aaca6eab848ed097406c8b4ff0b8c 586 Pfam PF11893 Domain of unknown function (DUF3413) 6 252 1.2E-105 T 28-03-2018 IPR024588 Inner membrane protein YejM, N-terminal WM46_RS02230 c85aaca6eab848ed097406c8b4ff0b8c 586 Gene3D G3DSA:3.40.720.10 258 529 8.2E-33 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS24245 ef903ef17feeb6325723584e35591ddc 88 SUPERFAMILY SSF109910 1 78 6.02E-27 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase WM46_RS24245 ef903ef17feeb6325723584e35591ddc 88 Pfam PF03937 Flavinator of succinate dehydrogenase 6 76 1.9E-25 T 28-03-2018 IPR005631 Flavinator of succinate dehydrogenase WM46_RS24245 ef903ef17feeb6325723584e35591ddc 88 Gene3D G3DSA:1.10.150.250 1 85 1.3E-26 T 28-03-2018 WM46_RS08320 7de2e66878b86f661073c058e67799bd 114 Gene3D G3DSA:3.40.1800.10 6 86 1.0E-7 T 28-03-2018 WM46_RS08320 7de2e66878b86f661073c058e67799bd 114 Pfam PF01844 HNH endonuclease 27 75 9.7E-12 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 WM46_RS08320 7de2e66878b86f661073c058e67799bd 114 SMART SM00507 15 70 1.4E-5 T 28-03-2018 IPR003615 HNH nuclease WM46_RS19790 aad4bba6c93064224aaa18822b95fa4a 29 Pfam PF13939 Toxin TisB, type I toxin-antitoxin system 1 28 3.9E-15 T 28-03-2018 IPR025211 Toxin TisB, type I toxin-antitoxin system GO:0005253|GO:0005887|GO:0009432|GO:0022611 WM46_RS19790 aad4bba6c93064224aaa18822b95fa4a 29 TIGRFAM TIGR04459 TisB_tox: type I toxin-antitoxin system toxin TisB 1 29 1.2E-17 T 28-03-2018 IPR025211 Toxin TisB, type I toxin-antitoxin system GO:0005253|GO:0005887|GO:0009432|GO:0022611 WM46_RS03280 b5feaa7bfc36686133e51af4e319d232 287 Gene3D G3DSA:3.90.226.10 64 286 1.4E-24 T 28-03-2018 WM46_RS03280 b5feaa7bfc36686133e51af4e319d232 287 Pfam PF01343 Peptidase family S49 141 280 5.3E-27 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 WM46_RS03280 b5feaa7bfc36686133e51af4e319d232 287 SUPERFAMILY SSF52096 64 185 3.89E-30 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS03280 b5feaa7bfc36686133e51af4e319d232 287 SUPERFAMILY SSF52096 216 274 3.89E-30 T 28-03-2018 IPR029045 ClpP/crotonase-like domain WM46_RS09825 b3a352ec32fb9d2eb7bae8ebab5a6722 410 Pfam PF06224 Winged helix DNA-binding domain 38 381 7.3E-82 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 WM46_RS18700 e1dd4062c648e0f6072e9e02b68b4742 445 SMART SM00327 65 244 6.0E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS18700 e1dd4062c648e0f6072e9e02b68b4742 445 Gene3D G3DSA:3.40.50.410 58 247 2.3E-33 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS18700 e1dd4062c648e0f6072e9e02b68b4742 445 SUPERFAMILY SSF53300 62 238 6.4E-33 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS18700 e1dd4062c648e0f6072e9e02b68b4742 445 Pfam PF00092 von Willebrand factor type A domain 67 236 2.3E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A WM46_RS02695 39b550e4694cf63d6266de2c534f3ed7 334 Pfam PF03747 ADP-ribosylglycohydrolase 8 301 3.3E-59 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 WM46_RS02695 39b550e4694cf63d6266de2c534f3ed7 334 SUPERFAMILY SSF101478 4 327 5.49E-68 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 WM46_RS02695 39b550e4694cf63d6266de2c534f3ed7 334 Gene3D G3DSA:1.10.4080.10 2 334 2.0E-67 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 WM46_RS13125 3ced7d66ce2da691765fce4e3a4f3481 310 PIRSF PIRSF037505 7 165 1.4E-5 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 WM46_RS13125 3ced7d66ce2da691765fce4e3a4f3481 310 PIRSF PIRSF037505 272 309 26.0 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 WM46_RS13125 3ced7d66ce2da691765fce4e3a4f3481 310 Gene3D G3DSA:3.20.20.330 1 309 4.0E-104 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM46_RS13125 3ced7d66ce2da691765fce4e3a4f3481 310 Pfam PF02574 Homocysteine S-methyltransferase 17 307 1.8E-80 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM46_RS13125 3ced7d66ce2da691765fce4e3a4f3481 310 SUPERFAMILY SSF82282 9 308 1.06E-85 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 WM46_RS19005 6e87c38825d52fc12041fd27b68ea62e 546 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 446 5.6E-186 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 WM46_RS19005 6e87c38825d52fc12041fd27b68ea62e 546 Pfam PF03109 ABC1 family 116 232 3.8E-34 T 28-03-2018 IPR004147 UbiB domain WM46_RS19005 6e87c38825d52fc12041fd27b68ea62e 546 SUPERFAMILY SSF56112 94 159 6.37E-49 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS19005 6e87c38825d52fc12041fd27b68ea62e 546 SUPERFAMILY SSF56112 194 438 6.37E-49 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS19005 6e87c38825d52fc12041fd27b68ea62e 546 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 542 56.836 T 28-03-2018 IPR010232 Probable protein kinase UbiB GO:0006744 WM46_RS19005 6e87c38825d52fc12041fd27b68ea62e 546 Gene3D G3DSA:3.30.200.20 103 245 2.7E-18 T 28-03-2018 WM46_RS06825 2c14562ebf3749f28e5f0fb0f27af2e0 47 Pfam PF08136 30S ribosomal protein subunit S22 family 1 43 6.2E-29 T 28-03-2018 IPR012607 Ribosomal protein S22 GO:0003735|GO:0005840|GO:0006412 WM46_RS06825 2c14562ebf3749f28e5f0fb0f27af2e0 47 ProDom PD049510 RIBOSOMAL S22 30S RIBONUCLEOPROTEIN SUBUNIT D RIBOSOME- SEQUENCING DIRECT ASSOCIATED 1 44 7.0E-17 T 28-03-2018 IPR012607 Ribosomal protein S22 GO:0003735|GO:0005840|GO:0006412 WM46_RS07860 17edbbc5925f28e21877176784dc4e78 283 SMART SM00849 36 218 4.6E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS07860 17edbbc5925f28e21877176784dc4e78 283 Gene3D G3DSA:3.60.15.10 20 247 4.3E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS07860 17edbbc5925f28e21877176784dc4e78 283 Pfam PF00753 Metallo-beta-lactamase superfamily 35 218 2.5E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS07860 17edbbc5925f28e21877176784dc4e78 283 SUPERFAMILY SSF56281 20 242 4.35E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS01030 994f58f2692cbee762477158c7a81049 350 SUPERFAMILY SSF46689 240 290 2.33E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS01030 994f58f2692cbee762477158c7a81049 350 SMART SM00342 256 342 9.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS01030 994f58f2692cbee762477158c7a81049 350 Gene3D G3DSA:1.10.10.60 293 349 1.2E-4 T 28-03-2018 WM46_RS01030 994f58f2692cbee762477158c7a81049 350 Gene3D G3DSA:1.10.10.60 154 292 4.4E-12 T 28-03-2018 WM46_RS01030 994f58f2692cbee762477158c7a81049 350 Pfam PF12833 Helix-turn-helix domain 262 342 6.0E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 WM46_RS01030 994f58f2692cbee762477158c7a81049 350 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 293 338 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 WM46_RS16560 f87697387cf1f82a7e73bdd349c3eb6e 274 SUPERFAMILY SSF161098 6 274 3.27E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS16560 f87697387cf1f82a7e73bdd349c3eb6e 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 267 8.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS16560 f87697387cf1f82a7e73bdd349c3eb6e 274 Gene3D G3DSA:1.10.3720.10 3 261 8.8E-43 T 28-03-2018 WM46_RS09030 df80d7639525aa957262029321922e7d 490 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 21 489 5.1E-208 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath WM46_RS09030 df80d7639525aa957262029321922e7d 490 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 69 488 3.2E-175 T 28-03-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath WM46_RS04045 7fb4a41efe457f59186294bcb27e5426 472 Pfam PF07690 Major Facilitator Superfamily 21 411 4.3E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS04045 7fb4a41efe457f59186294bcb27e5426 472 Gene3D G3DSA:1.20.1250.20 9 202 3.8E-32 T 28-03-2018 WM46_RS04045 7fb4a41efe457f59186294bcb27e5426 472 SUPERFAMILY SSF103473 15 205 1.7E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04045 7fb4a41efe457f59186294bcb27e5426 472 SUPERFAMILY SSF103473 251 462 1.7E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04045 7fb4a41efe457f59186294bcb27e5426 472 Gene3D G3DSA:1.20.1250.20 261 471 2.0E-16 T 28-03-2018 WM46_RS19875 c758bb791aa40c113ac6050b2c786ca0 119 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 1 113 1.0E-38 T 28-03-2018 IPR009387 Toxin HigB-2 WM46_RS19875 c758bb791aa40c113ac6050b2c786ca0 119 PIRSF PIRSF018634 1 117 1.0E-44 T 28-03-2018 IPR009387 Toxin HigB-2 WM46_RS23580 6b9d908e94c4344bb56b084740049168 154 Pfam PF11682 Probable zinc-ribbon 4 125 3.1E-25 T 28-03-2018 IPR021696 Protein of unknown function DUF3279 WM46_RS19490 53a8ba515e66519e2c471709b4d7da85 126 Pfam PF03899 ATP synthase I chain 13 108 5.5E-14 T 28-03-2018 IPR005598 ATP synthase protein I WM46_RS25660 c760201f1a60e669c586b2cfce9c3a20 143 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 77 2.7E-15 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS25660 c760201f1a60e669c586b2cfce9c3a20 143 SUPERFAMILY SSF69118 8 143 3.99E-41 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS25660 c760201f1a60e669c586b2cfce9c3a20 143 Pfam PF02627 Carboxymuconolactone decarboxylase family 13 94 1.3E-19 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 WM46_RS25660 c760201f1a60e669c586b2cfce9c3a20 143 Gene3D G3DSA:1.20.1290.10 2 143 2.3E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 PRINTS PR00421 Thioredoxin family signature 21 29 6.6E-7 T 28-03-2018 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 PRINTS PR00421 Thioredoxin family signature 69 80 6.6E-7 T 28-03-2018 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 PRINTS PR00421 Thioredoxin family signature 29 38 6.6E-7 T 28-03-2018 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 SUPERFAMILY SSF52833 6 102 4.36E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 Gene3D G3DSA:3.40.30.10 71 108 0.0012 T 28-03-2018 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 Pfam PF00085 Thioredoxin 11 102 2.9E-22 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 Gene3D G3DSA:3.40.30.10 3 70 9.2E-21 T 28-03-2018 WM46_RS15430 024b59178a9642e71d062724fa1b16bf 109 PIRSF PIRSF000077 3 104 1.1E-28 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 WM46_RS08275 0981bc0f4adcf8c1d4ac1aefe66c9616 577 SUPERFAMILY SSF53649 4 385 2.22E-76 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS08275 0981bc0f4adcf8c1d4ac1aefe66c9616 577 SUPERFAMILY SSF53649 439 478 2.22E-76 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS08275 0981bc0f4adcf8c1d4ac1aefe66c9616 577 Gene3D G3DSA:3.40.720.10 3 354 1.8E-59 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS08275 0981bc0f4adcf8c1d4ac1aefe66c9616 577 Pfam PF00884 Sulfatase 4 334 1.8E-33 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS10885 b61d8cc0e224e744e20d62ae3c19c0a4 456 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 62 312 3.4E-19 T 28-03-2018 IPR010839 Acyclic terpene utilisation WM46_RS05860 051f2f00d4c5e128b6ea96261729aab0 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 204 5.6E-79 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 WM46_RS05860 051f2f00d4c5e128b6ea96261729aab0 206 Gene3D G3DSA:3.90.870.10 1 206 8.3E-61 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS05860 051f2f00d4c5e128b6ea96261729aab0 206 SUPERFAMILY SSF55821 1 204 2.93E-66 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain WM46_RS05860 051f2f00d4c5e128b6ea96261729aab0 206 Pfam PF01300 Telomere recombination 23 198 3.6E-46 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 WM46_RS16185 d5302a3d16604174232b0c6d90e30c46 118 Pfam PF04380 Membrane fusogenic activity 21 98 9.6E-29 T 28-03-2018 IPR007475 Membrane fusogenic activity WM46_RS21830 674225b39387020090bae6fd9c992d42 252 Gene3D G3DSA:3.60.15.10 1 252 2.6E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS21830 674225b39387020090bae6fd9c992d42 252 Pfam PF12706 Beta-lactamase superfamily domain 73 223 8.3E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS21830 674225b39387020090bae6fd9c992d42 252 SUPERFAMILY SSF56281 5 251 4.9E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase WM46_RS21830 674225b39387020090bae6fd9c992d42 252 TIGRFAM TIGR03307 PhnP: phosphonate metabolism protein PhnP 4 248 3.5E-121 T 28-03-2018 IPR017693 Phosphonate metabolism protein PhnP GO:0008081|GO:0019700 KEGG: 00440+3.1.4.55|MetaCyc: PWY-7805|MetaCyc: PWY-7807 WM46_RS23445 94c2cd54d6362d5ba0181f90abb82a6d 439 PIRSF PIRSF002746 1 439 8.6E-158 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS23445 94c2cd54d6362d5ba0181f90abb82a6d 439 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 438 5.2E-198 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS23445 94c2cd54d6362d5ba0181f90abb82a6d 439 Pfam PF02447 GntP family permease 1 436 1.1E-182 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 WM46_RS16495 aa8e0d31c27e590d5f21f56ea9fe5934 443 Hamap MF_01583 Threonine/serine transporter TdcC [tdcC]. 1 443 57.135 T 28-03-2018 IPR023726 Threonine/serine transporter TdcC GO:0015565|GO:0015826|GO:0016021|GO:0022889|GO:0032329 WM46_RS16495 aa8e0d31c27e590d5f21f56ea9fe5934 443 Pfam PF03222 Tryptophan/tyrosine permease family 29 438 6.5E-8 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 WM46_RS16495 aa8e0d31c27e590d5f21f56ea9fe5934 443 TIGRFAM TIGR00814 stp: serine transporter 17 433 1.2E-171 T 28-03-2018 IPR004694 Hydroxy amino acid transporter GO:0005215|GO:0006810|GO:0016021 WM46_RS10630 5f74f5afa2f063cef11e513107114fa3 427 SUPERFAMILY SSF51126 76 157 2.09E-37 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS10630 5f74f5afa2f063cef11e513107114fa3 427 SUPERFAMILY SSF51126 407 419 2.09E-37 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS10630 5f74f5afa2f063cef11e513107114fa3 427 SUPERFAMILY SSF51126 192 376 2.09E-37 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS10630 5f74f5afa2f063cef11e513107114fa3 427 ProSitePatterns PS00503 Pectinesterase signature 2. 280 289 - T 28-03-2018 IPR033131 Pectinesterase, Asp active site KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 WM46_RS10630 5f74f5afa2f063cef11e513107114fa3 427 Gene3D G3DSA:2.160.20.10 74 426 5.3E-49 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS10630 5f74f5afa2f063cef11e513107114fa3 427 Pfam PF01095 Pectinesterase 196 340 3.7E-10 T 28-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 WM46_RS23130 3a697e78939192c332e2d540a14ec562 1258 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 922 1258 6.5E-68 T 28-03-2018 IPR007452 Translocation and assembly module TamB WM46_RS03965 b588abe0f3e5ac919d6d8cf9a578289c 425 Gene3D G3DSA:3.90.220.20 1 180 1.7E-29 T 28-03-2018 WM46_RS03965 b588abe0f3e5ac919d6d8cf9a578289c 425 Gene3D G3DSA:3.90.220.20 181 395 3.0E-27 T 28-03-2018 WM46_RS03965 b588abe0f3e5ac919d6d8cf9a578289c 425 Pfam PF01420 Type I restriction modification DNA specificity domain 4 184 2.3E-14 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 WM46_RS03965 b588abe0f3e5ac919d6d8cf9a578289c 425 Pfam PF01420 Type I restriction modification DNA specificity domain 223 393 1.9E-8 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 WM46_RS03965 b588abe0f3e5ac919d6d8cf9a578289c 425 SUPERFAMILY SSF116734 2 205 1.41E-43 T 28-03-2018 WM46_RS03965 b588abe0f3e5ac919d6d8cf9a578289c 425 SUPERFAMILY SSF116734 214 417 5.72E-33 T 28-03-2018 WM46_RS07960 02e51cabfaf16d8f6629867d0634ea07 277 Gene3D G3DSA:3.40.50.300 151 191 0.28 T 28-03-2018 WM46_RS07960 02e51cabfaf16d8f6629867d0634ea07 277 Pfam PF03618 Kinase/pyrophosphorylase 9 267 5.8E-72 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 WM46_RS07960 02e51cabfaf16d8f6629867d0634ea07 277 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 6 276 72.361 T 28-03-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein WM46_RS07960 02e51cabfaf16d8f6629867d0634ea07 277 Gene3D G3DSA:3.40.50.300 192 274 7.2E-5 T 28-03-2018 WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 Gene3D G3DSA:3.20.70.20 2 760 7.5E-297 T 28-03-2018 WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 PIRSF PIRSF000379 8 760 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 760 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 Pfam PF01228 Glycine radical 630 741 1.4E-43 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 SUPERFAMILY SSF51998 4 759 2.14E-293 T 28-03-2018 WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 ProSitePatterns PS00850 Glycine radical domain signature. 730 738 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site WM46_RS09890 000a77ee6cf38186ded75c4f3306db3d 760 Pfam PF02901 Pyruvate formate lyase-like 23 614 6.7E-207 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 183 1.5E-22 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 SUPERFAMILY SSF56784 4 212 3.14E-46 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 Gene3D G3DSA:3.40.50.1000 77 218 5.0E-19 T 28-03-2018 IPR023214 HAD-like domain WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 Gene3D G3DSA:1.10.150.240 19 76 1.1E-18 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 183 8.6E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 7.8E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 7.8E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS19575 5dedfa43d005f5b58ee8d76c71c62acc 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 97 110 7.8E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 WM46_RS06935 a90814dc2c88ee59b82a9dfdc95c61dd 341 Pfam PF05707 Zonular occludens toxin (Zot) 4 196 6.6E-27 T 28-03-2018 IPR008900 Zona occludens toxin WM46_RS06935 a90814dc2c88ee59b82a9dfdc95c61dd 341 Gene3D G3DSA:3.40.50.300 2 200 2.6E-8 T 28-03-2018 WM46_RS02185 2f99d15b420c7bffb6417ef3c03acfd0 159 Gene3D G3DSA:2.40.50.140 27 131 1.6E-33 T 28-03-2018 WM46_RS02185 2f99d15b420c7bffb6417ef3c03acfd0 159 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 147 31.372 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 WM46_RS02185 2f99d15b420c7bffb6417ef3c03acfd0 159 SUPERFAMILY SSF82093 30 143 3.66E-40 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 WM46_RS02185 2f99d15b420c7bffb6417ef3c03acfd0 159 Pfam PF03100 CcmE 4 137 2.9E-46 T 28-03-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 WM46_RS24005 ffbe259834e5f3f4c3917b01291aa26b 448 PIRSF PIRSF006351 10 445 1.5E-140 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 WM46_RS24005 ffbe259834e5f3f4c3917b01291aa26b 448 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 21 435 1.0E-110 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 WM46_RS24005 ffbe259834e5f3f4c3917b01291aa26b 448 Pfam PF02378 Phosphotransferase system, EIIC 37 360 3.5E-56 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 WM46_RS05055 ac1b2c5b7910dba8a664ea35efa0911d 60 Pfam PF08956 Domain of unknown function (DUF1869) 3 60 1.1E-31 T 28-03-2018 IPR015051 Protein YoaG WM46_RS05055 ac1b2c5b7910dba8a664ea35efa0911d 60 SUPERFAMILY SSF103063 1 60 8.63E-32 T 28-03-2018 IPR015051 Protein YoaG WM46_RS05055 ac1b2c5b7910dba8a664ea35efa0911d 60 Gene3D G3DSA:3.30.160.220 3 55 2.0E-28 T 28-03-2018 IPR015051 Protein YoaG WM46_RS10260 405b69cd43f631e2495f31a298839479 127 Pfam PF10799 Biofilm formation protein (YliH/bssR) 1 125 9.4E-72 T 28-03-2018 IPR020359 Biofilm regulator BssR WM46_RS10260 405b69cd43f631e2495f31a298839479 127 ProDom PD079626 YLIH RECEPTOR STY0893 CYTOPLASMIC 1 127 9.0E-45 T 28-03-2018 IPR020359 Biofilm regulator BssR WM46_RS19340 a634f7d751db38b17a450ee1922a14f2 87 Gene3D G3DSA:3.30.70.260 1 79 3.1E-7 T 28-03-2018 WM46_RS19340 a634f7d751db38b17a450ee1922a14f2 87 SUPERFAMILY SSF55021 3 75 2.29E-11 T 28-03-2018 WM46_RS19340 a634f7d751db38b17a450ee1922a14f2 87 Pfam PF13710 ACT domain 13 73 1.1E-26 T 28-03-2018 WM46_RS25160 64cfec2082509b139644b9450c0269da 432 Pfam PF07690 Major Facilitator Superfamily 26 365 2.3E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS25160 64cfec2082509b139644b9450c0269da 432 SUPERFAMILY SSF103473 5 414 3.27E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS25160 64cfec2082509b139644b9450c0269da 432 Gene3D G3DSA:1.20.1250.20 211 422 1.2E-13 T 28-03-2018 WM46_RS25160 64cfec2082509b139644b9450c0269da 432 Gene3D G3DSA:1.20.1250.20 2 209 1.0E-23 T 28-03-2018 WM46_RS03325 723157095b466b572115a0c9897bd4fa 123 Pfam PF10618 Phage tail tube protein 7 121 1.0E-36 T 28-03-2018 IPR019596 Bacteriophage Mu, GpM, tail tube WM46_RS15360 1c77e5c812c3966ab61332db6c7e3c14 95 Pfam PF01638 HxlR-like helix-turn-helix 3 81 2.2E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type WM46_RS15360 1c77e5c812c3966ab61332db6c7e3c14 95 SUPERFAMILY SSF46785 3 90 3.96E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS15360 1c77e5c812c3966ab61332db6c7e3c14 95 Gene3D G3DSA:1.10.10.10 1 95 6.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS11135 18277887ebc452acf37b5b1bd4e2327e 163 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 10 154 6.9E-22 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related WM46_RS11135 18277887ebc452acf37b5b1bd4e2327e 163 SUPERFAMILY SSF50475 3 156 2.75E-41 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS11135 18277887ebc452acf37b5b1bd4e2327e 163 Gene3D G3DSA:2.30.110.10 1 161 6.7E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 WM46_RS19200 f1805731b0303f4551e2ec4705a5462c 450 Pfam PF06899 WzyE protein, O-antigen assembly polymerase 1 442 1.1E-261 T 28-03-2018 IPR010691 Probable ECA polymerase WzyE GO:0009246|GO:0016021 WM46_RS19200 f1805731b0303f4551e2ec4705a5462c 450 Hamap MF_01003 Probable ECA polymerase [wzyE]. 1 448 41.751 T 28-03-2018 IPR010691 Probable ECA polymerase WzyE GO:0009246|GO:0016021 WM46_RS11740 0c1d129556a1f06c80a1396cf87e0749 82 Pfam PF06643 Protein of unknown function (DUF1158) 1 79 9.6E-47 T 28-03-2018 IPR010590 Protein of unknown function DUF1158 WM46_RS11740 0c1d129556a1f06c80a1396cf87e0749 82 ProDom PD027061 YBDJ MEMBRANE TRANSMEMBRANE INNER RAMA 3'REGION ECS0618 1 81 7.0E-21 T 28-03-2018 IPR010590 Protein of unknown function DUF1158 WM46_RS09415 446ebb57c3d9804d6d7fd1e8b07b6b6b 107 SUPERFAMILY SSF54909 1 107 1.66E-28 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS09415 446ebb57c3d9804d6d7fd1e8b07b6b6b 107 Pfam PF05336 L-rhamnose mutarotase 3 106 7.9E-33 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 Pfam PF03170 Bacterial cellulose synthase subunit 76 685 1.2E-224 T 28-03-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 318 339 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 534 553 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 195 216 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 105 126 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 401 422 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 237 260 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS20665 34ea992d0fb3ed79a8167c804a36ac5a 784 PRINTS PR01440 Cellulose synthase subunit B signature 571 591 9.5E-30 T 28-03-2018 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 WM46_RS14755 4646058bcbc3914cd315a942aaaab121 253 Gene3D G3DSA:2.40.230.20 94 246 1.1E-7 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS14755 4646058bcbc3914cd315a942aaaab121 253 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 100 253 4.7E-17 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS14755 4646058bcbc3914cd315a942aaaab121 253 SUPERFAMILY SSF111364 31 253 2.35E-14 T 28-03-2018 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 WM46_RS08145 498b3e11e7ae1a201b4a74b5bf5af0e4 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 94 9.4E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS08145 498b3e11e7ae1a201b4a74b5bf5af0e4 106 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 1 94 2.1E-33 T 28-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 WM46_RS08145 498b3e11e7ae1a201b4a74b5bf5af0e4 106 Gene3D G3DSA:3.40.50.2300 5 106 8.8E-29 T 28-03-2018 WM46_RS08145 498b3e11e7ae1a201b4a74b5bf5af0e4 106 SUPERFAMILY SSF52794 4 102 4.71E-32 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS15850 a29b4e42416f13a3ba17c5cd6099ed62 274 Pfam PF06067 Domain of unknown function (DUF932) 36 261 1.7E-56 T 28-03-2018 IPR026325 Protein of unknown function DUF932 WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 Pfam PF01497 Periplasmic binding protein 38 270 1.4E-28 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 Gene3D G3DSA:3.40.50.1980 31 122 7.5E-12 T 28-03-2018 WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 SUPERFAMILY SSF53807 34 292 2.55E-56 T 28-03-2018 WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 Gene3D G3DSA:3.40.50.1980 123 296 8.9E-27 T 28-03-2018 WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 55 73 5.8E-55 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 273 286 5.8E-55 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 184 199 5.8E-55 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 236 253 5.8E-55 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 208 226 5.8E-55 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein WM46_RS14055 81ff5cf371e1348dab261f8115d75263 296 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 86 101 5.8E-55 T 28-03-2018 IPR008091 Ferrichrome-binding periplasmic protein WM46_RS04370 916041390c65f398180812e41f5b1d4e 117 ProDom PD077599 YEBF LIPOPROTEIN EXPORTED PERIPLASMIC PRECURSOR SIGNAL SIMILAR PALMITATE MEMBRANE ESCHERICHIA 24 115 1.0E-40 T 28-03-2018 IPR025603 YebF/Colicin-M immunity protein WM46_RS04370 916041390c65f398180812e41f5b1d4e 117 Pfam PF13995 YebF-like protein 27 114 5.4E-40 T 28-03-2018 IPR025603 YebF/Colicin-M immunity protein WM46_RS25625 921d702c8c3c5261d0fcb9446fb7da9a 354 Gene3D G3DSA:1.10.3720.10 106 336 3.1E-36 T 28-03-2018 WM46_RS25625 921d702c8c3c5261d0fcb9446fb7da9a 354 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 324 7.3E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS25625 921d702c8c3c5261d0fcb9446fb7da9a 354 SUPERFAMILY SSF161098 142 324 7.85E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS04560 d515d76ec168d5c8eb09338713c25173 315 Pfam PF04492 Bacteriophage replication protein O 1 112 1.4E-21 T 28-03-2018 IPR006497 Bacteriophage lambda, GpO, N-terminal GO:0006260 WM46_RS04560 d515d76ec168d5c8eb09338713c25173 315 Gene3D G3DSA:1.10.10.10 68 138 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS22515 bdddc3756a3c911aa123eafe1ecb980a 120 Pfam PF05666 Fels-1 Prophage Protein-like 69 118 5.6E-11 T 28-03-2018 IPR008617 Uncharacterised protein family, YcgJ WM46_RS22515 bdddc3756a3c911aa123eafe1ecb980a 120 Pfam PF05666 Fels-1 Prophage Protein-like 26 60 7.0E-12 T 28-03-2018 IPR008617 Uncharacterised protein family, YcgJ WM46_RS20370 0a36d1312757f10df97be9813126a32e 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 375 4.2E-120 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 WM46_RS20370 0a36d1312757f10df97be9813126a32e 383 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS20370 0a36d1312757f10df97be9813126a32e 383 Gene3D G3DSA:1.20.1090.10 184 383 2.6E-66 T 28-03-2018 WM46_RS20370 0a36d1312757f10df97be9813126a32e 383 Gene3D G3DSA:3.40.50.1970 9 183 2.0E-45 T 28-03-2018 WM46_RS20370 0a36d1312757f10df97be9813126a32e 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 WM46_RS20370 0a36d1312757f10df97be9813126a32e 383 SUPERFAMILY SSF56796 5 382 3.4E-131 T 28-03-2018 WM46_RS18085 debe05be0846626b56b2780a177de170 248 Gene3D G3DSA:3.20.20.190 2 242 8.0E-58 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 WM46_RS18085 debe05be0846626b56b2780a177de170 248 SUPERFAMILY SSF51695 5 239 3.66E-60 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 WM46_RS18085 debe05be0846626b56b2780a177de170 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 238 1.0E-38 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 WM46_RS00550 8ea419b29968523f24f0ffae59a0d2ff 199 Pfam PF01380 SIS domain 38 166 1.2E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 WM46_RS00550 8ea419b29968523f24f0ffae59a0d2ff 199 SUPERFAMILY SSF53697 8 192 5.56E-33 T 28-03-2018 WM46_RS00550 8ea419b29968523f24f0ffae59a0d2ff 199 Gene3D G3DSA:3.40.50.10490 5 198 9.3E-38 T 28-03-2018 WM46_RS24470 b2adec68da9ccad26f2f8540a4eef8a9 624 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 165 6.5E-25 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component WM46_RS24470 b2adec68da9ccad26f2f8540a4eef8a9 624 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 214 619 1.8E-87 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 WM46_RS24470 b2adec68da9ccad26f2f8540a4eef8a9 624 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 204 613 1.3E-93 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit WM46_RS02825 40924dc7dab9dec8809b945bd3874981 406 TIGRFAM TIGR04010 WcaD: putative colanic acid polymerase WcaD 1 404 9.1E-264 T 28-03-2018 IPR024013 Colanic acid biosynthesis, putative colanic acid polymerase, WcaD WM46_RS23255 c0ee3eabab9f80a5fe6c37fbfcb80ac6 154 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 153 3.7E-65 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 WM46_RS23255 c0ee3eabab9f80a5fe6c37fbfcb80ac6 154 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 WM46_RS23255 c0ee3eabab9f80a5fe6c37fbfcb80ac6 154 Gene3D G3DSA:3.20.20.70 12 129 1.6E-10 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS23255 c0ee3eabab9f80a5fe6c37fbfcb80ac6 154 SUPERFAMILY SSF102114 24 105 3.66E-6 T 28-03-2018 WM46_RS23255 c0ee3eabab9f80a5fe6c37fbfcb80ac6 154 Pfam PF13353 4Fe-4S single cluster domain 12 151 1.9E-51 T 28-03-2018 WM46_RS23255 c0ee3eabab9f80a5fe6c37fbfcb80ac6 154 PIRSF PIRSF000368 1 154 1.0E-60 T 28-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 WM46_RS01430 2a30b31b13d8a6a3360825e602b25011 199 Pfam PF06353 Protein of unknown function (DUF1062) 36 166 6.1E-37 T 28-03-2018 IPR009412 Protein of unknown function DUF1062 WM46_RS01430 2a30b31b13d8a6a3360825e602b25011 199 PIRSF PIRSF021719 1 198 9.2E-66 T 28-03-2018 IPR009412 Protein of unknown function DUF1062 WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 SUPERFAMILY SSF161098 261 503 2.22E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 Pfam PF14785 Maltose transport system permease protein MalF P2 domain 100 260 2.4E-60 T 28-03-2018 IPR029345 Maltose transport system permease protein MalF, P2 domain WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 Gene3D G3DSA:1.20.58.370 4 95 2.1E-32 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 297 501 4.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 Gene3D G3DSA:3.10.650.10 197 269 2.9E-28 T 28-03-2018 WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 SUPERFAMILY SSF160964 15 260 2.09E-89 T 28-03-2018 WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 Gene3D G3DSA:2.40.430.10 119 196 2.0E-29 T 28-03-2018 WM46_RS21545 b86f826eb5a24008e8217881fc712a8e 514 Gene3D G3DSA:1.10.3720.10 270 514 5.2E-43 T 28-03-2018 WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 Gene3D G3DSA:3.30.390.10 1 125 7.8E-20 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 SUPERFAMILY SSF51604 106 350 5.5E-50 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 SUPERFAMILY SSF54826 1 119 2.69E-22 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 SMART SM00922 137 237 9.1E-17 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 Gene3D G3DSA:3.20.20.120 126 345 3.6E-43 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 Pfam PF13378 Enolase C-terminal domain-like 145 347 1.2E-44 T 28-03-2018 IPR029065 Enolase C-terminal domain-like WM46_RS09385 60d972deb6ec8dcc86d1876cf7f9979c 390 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 32 118 3.8E-8 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain WM46_RS22720 cc2e8f094494e7483f748b14ea252dee 158 Pfam PF04186 FxsA cytoplasmic membrane protein 8 110 1.4E-33 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 WM46_RS23995 376868fd47573dd83213884dc940230c 210 Gene3D G3DSA:1.10.10.10 49 207 8.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23995 376868fd47573dd83213884dc940230c 210 SUPERFAMILY SSF46894 145 206 1.05E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 WM46_RS23995 376868fd47573dd83213884dc940230c 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS23995 376868fd47573dd83213884dc940230c 210 SMART SM00421 149 206 3.2E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS23995 376868fd47573dd83213884dc940230c 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 7.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS23995 376868fd47573dd83213884dc940230c 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 7.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS23995 376868fd47573dd83213884dc940230c 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 7.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 WM46_RS19295 84da8f361490de634cfae00987844cbb 247 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 WM46_RS19295 84da8f361490de634cfae00987844cbb 247 Gene3D G3DSA:3.40.50.1580 1 236 1.7E-48 T 28-03-2018 WM46_RS19295 84da8f361490de634cfae00987844cbb 247 SUPERFAMILY SSF53167 1 204 7.86E-64 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS19295 84da8f361490de634cfae00987844cbb 247 Pfam PF01048 Phosphorylase superfamily 15 201 6.4E-36 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 WM46_RS19685 98265676cf02606daf77cf820264b24d 205 Gene3D G3DSA:3.20.20.70 1 205 2.8E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS19685 98265676cf02606daf77cf820264b24d 205 Pfam PF01081 KDPG and KHG aldolase 6 183 2.6E-30 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 WM46_RS19685 98265676cf02606daf77cf820264b24d 205 SUPERFAMILY SSF51569 2 204 4.76E-60 T 28-03-2018 WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 Pfam PF00580 UvrD/REP helicase N-terminal domain 197 490 1.3E-42 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 SUPERFAMILY SSF52540 195 330 3.62E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 SUPERFAMILY SSF52540 385 676 3.62E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 Pfam PF13361 UvrD-like helicase C-terminal domain 543 663 8.0E-14 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 Gene3D G3DSA:3.40.50.300 187 499 1.6E-44 T 28-03-2018 WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 Pfam PF12462 DNA helicase IV / RNA helicase N terminal 1 164 9.4E-62 T 28-03-2018 IPR022161 DNA helicase IV, N-terminal domain WM46_RS09620 5fd159822a2ab1af57aa27d14a4df2fb 684 Gene3D G3DSA:3.40.50.300 500 680 1.9E-28 T 28-03-2018 WM46_RS19425 804df631640d37daa6cb6579acf77f2c 296 Gene3D G3DSA:3.40.50.2300 27 137 8.4E-27 T 28-03-2018 WM46_RS19425 804df631640d37daa6cb6579acf77f2c 296 Pfam PF13407 Periplasmic binding protein domain 29 281 2.3E-58 T 28-03-2018 IPR025997 Periplasmic binding protein WM46_RS19425 804df631640d37daa6cb6579acf77f2c 296 Gene3D G3DSA:3.40.50.2300 138 293 7.4E-43 T 28-03-2018 WM46_RS19425 804df631640d37daa6cb6579acf77f2c 296 SUPERFAMILY SSF53822 26 295 6.02E-89 T 28-03-2018 IPR028082 Periplasmic binding protein-like I WM46_RS15105 5461df221e5f8be7d38e9d9aa34c963e 335 Pfam PF06717 Protein of unknown function (DUF1202) 14 320 1.4E-170 T 28-03-2018 IPR009592 Protein of unknown function DUF1202 WM46_RS01985 27e30239448494b3ad971ba83c62b98c 212 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 7 209 1.1E-66 T 28-03-2018 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 WM46_RS01985 27e30239448494b3ad971ba83c62b98c 212 PIRSF PIRSF026326 1 212 7.5E-63 T 28-03-2018 IPR027023 Putative lipopolysaccharide kinase InaA WM46_RS01985 27e30239448494b3ad971ba83c62b98c 212 SUPERFAMILY SSF56112 35 175 1.59E-7 T 28-03-2018 IPR011009 Protein kinase-like domain WM46_RS15510 b205c17d80a785e1b1a0bafac6a425b4 307 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 4 78 2.1E-26 T 28-03-2018 IPR021877 Protein of unknown function DUF3487 WM46_RS15510 b205c17d80a785e1b1a0bafac6a425b4 307 Pfam PF11990 Protein of unknown function (DUF3487) 2 78 1.4E-27 T 28-03-2018 IPR021877 Protein of unknown function DUF3487 WM46_RS15995 1466d19a427fda8fb5ec71b43a780af5 141 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 15 136 2.4E-69 T 28-03-2018 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 WM46_RS15995 1466d19a427fda8fb5ec71b43a780af5 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 133 1.6E-31 T 28-03-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 WM46_RS19445 a2938cb73d1dc646f8fb4fdb31088773 622 TIGRFAM TIGR00794 kup: potassium uptake protein 97 550 1.5E-200 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 WM46_RS19445 a2938cb73d1dc646f8fb4fdb31088773 622 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 5 622 33.521 T 28-03-2018 IPR023051 Potassium uptake protein, low affinity, Kup WM46_RS19445 a2938cb73d1dc646f8fb4fdb31088773 622 Pfam PF02705 K+ potassium transporter 14 544 3.1E-207 T 28-03-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 WM46_RS01790 597739f7093cb04538acb5e27ae29607 325 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 56 71 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01790 597739f7093cb04538acb5e27ae29607 325 Pfam PF00146 NADH dehydrogenase 17 317 7.4E-121 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01790 597739f7093cb04538acb5e27ae29607 325 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 323 24.072 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS01790 597739f7093cb04538acb5e27ae29607 325 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 211 224 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 WM46_RS06015 40b891392ef190f5abbee68ca716c019 109 Pfam PF13954 PapC N-terminal domain 57 108 1.0E-12 T 28-03-2018 IPR025885 PapC, N-terminal domain GO:0005515 WM46_RS06015 40b891392ef190f5abbee68ca716c019 109 SUPERFAMILY SSF141729 57 108 5.14E-14 T 28-03-2018 WM46_RS04885 14bd7366f247c34d5528899e00ddf662 293 Pfam PF01435 Peptidase family M48 73 288 8.0E-40 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 WM46_RS04885 14bd7366f247c34d5528899e00ddf662 293 Gene3D G3DSA:3.30.2010.10 64 157 5.8E-21 T 28-03-2018 WM46_RS04885 14bd7366f247c34d5528899e00ddf662 293 Hamap MF_00188 Protease HtpX [htpX]. 1 289 27.225 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 WM46_RS09175 b23729f85ff39f9242be2a6a8e8a1e9d 162 Gene3D G3DSA:1.10.10.10 5 140 3.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS08740 bd9764fd696ba42421916a2cd646903b 317 SUPERFAMILY SSF64518 1 315 1.44E-60 T 28-03-2018 WM46_RS08740 bd9764fd696ba42421916a2cd646903b 317 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 193 4.4E-69 T 28-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 WM46_RS08740 bd9764fd696ba42421916a2cd646903b 317 Gene3D G3DSA:1.20.1330.10 38 291 3.2E-22 T 28-03-2018 WM46_RS08740 bd9764fd696ba42421916a2cd646903b 317 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 141 2.5E-31 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 WM46_RS06080 32abb7749d1a74f901e8485b40316a6f 74 Pfam PF06667 Phage shock protein B 3 73 6.9E-32 T 28-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 WM46_RS06080 32abb7749d1a74f901e8485b40316a6f 74 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 1 74 1.5E-32 T 28-03-2018 IPR009554 Phage shock protein B GO:0006355|GO:0009271 WM46_RS10005 489cc09cc9dd8bec43df7ed5888e394d 131 Gene3D G3DSA:3.10.180.10 1 131 9.7E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS10005 489cc09cc9dd8bec43df7ed5888e394d 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 123 3.9E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM46_RS10005 489cc09cc9dd8bec43df7ed5888e394d 131 SUPERFAMILY SSF54593 2 128 5.2E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS21485 4896c66921b3522311ff0211ea6eda6f 408 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 33 62 - T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 WM46_RS21485 4896c66921b3522311ff0211ea6eda6f 408 Pfam PF01139 tRNA-splicing ligase RtcB 33 408 1.9E-133 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 WM46_RS21485 4896c66921b3522311ff0211ea6eda6f 408 SUPERFAMILY SSF103365 14 408 7.85E-141 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 WM46_RS24600 c9566bc0cd04b0b909edff73a0391c4b 176 Gene3D G3DSA:2.60.40.1090 25 176 8.3E-35 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24600 c9566bc0cd04b0b909edff73a0391c4b 176 Pfam PF00419 Fimbrial protein 28 176 7.0E-18 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS24600 c9566bc0cd04b0b909edff73a0391c4b 176 SUPERFAMILY SSF49401 33 176 2.49E-33 T 28-03-2018 IPR008966 Adhesion domain WM46_RS23425 f9e0dd3af6aec471c92c1106b1d870ab 366 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 348 3.3E-116 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 WM46_RS23425 f9e0dd3af6aec471c92c1106b1d870ab 366 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 343 1.5E-72 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM46_RS22940 dc437a0ce5cd8d2f072fa9c253367b3b 256 Gene3D G3DSA:1.10.3720.10 3 254 1.4E-26 T 28-03-2018 WM46_RS22940 dc437a0ce5cd8d2f072fa9c253367b3b 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 250 2.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS22940 dc437a0ce5cd8d2f072fa9c253367b3b 256 SUPERFAMILY SSF161098 58 240 5.36E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01165 812f48c044efcee670fdc460977afefc 332 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 8 316 2.0E-101 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter WM46_RS01165 812f48c044efcee670fdc460977afefc 332 PIRSF PIRSF026166 1 332 4.9E-135 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter WM46_RS10225 479fc61cad6a7632224aa313d94c191e 413 Pfam PF07690 Major Facilitator Superfamily 27 361 1.1E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS10225 479fc61cad6a7632224aa313d94c191e 413 Gene3D G3DSA:1.20.1250.20 210 406 8.8E-9 T 28-03-2018 WM46_RS10225 479fc61cad6a7632224aa313d94c191e 413 SUPERFAMILY SSF103473 10 398 5.49E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS10225 479fc61cad6a7632224aa313d94c191e 413 Gene3D G3DSA:1.20.1250.20 5 199 7.4E-25 T 28-03-2018 WM46_RS10225 479fc61cad6a7632224aa313d94c191e 413 ProSitePatterns PS00216 Sugar transport proteins signature 1. 72 88 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 WM46_RS20645 7fa419c3ef0b2eded02dfdb02432744a 519 Pfam PF10995 GGDEF I-site like or GIL domain 161 470 1.9E-122 T 28-03-2018 IPR017745 Cellulose biosynthesis protein BcsE WM46_RS20645 7fa419c3ef0b2eded02dfdb02432744a 519 TIGRFAM TIGR03369 cellulose_bcsE: cellulose biosynthesis protein BcsE 156 471 2.2E-125 T 28-03-2018 IPR017745 Cellulose biosynthesis protein BcsE WM46_RS04365 af65fdd56611e4a39658ada81e06883a 96 Pfam PF07130 YebG protein 1 74 4.5E-34 T 28-03-2018 IPR009813 Uncharacterised protein family YebG WM46_RS04365 af65fdd56611e4a39658ada81e06883a 96 Gene3D G3DSA:1.10.10.710 22 82 3.3E-26 T 28-03-2018 WM46_RS25640 bce0890eb99460569f852f8d2e13a078 319 Pfam PF00268 Ribonucleotide reductase, small chain 9 280 1.8E-84 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25640 bce0890eb99460569f852f8d2e13a078 319 Gene3D G3DSA:1.10.620.20 1 292 1.1E-75 T 28-03-2018 WM46_RS25640 bce0890eb99460569f852f8d2e13a078 319 PIRSF PIRSF000355 1 316 1.9E-78 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25640 bce0890eb99460569f852f8d2e13a078 319 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 97 113 - T 28-03-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 WM46_RS25640 bce0890eb99460569f852f8d2e13a078 319 SUPERFAMILY SSF47240 6 319 2.43E-101 T 28-03-2018 IPR009078 Ferritin-like superfamily WM46_RS25640 bce0890eb99460569f852f8d2e13a078 319 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 7 319 7.0E-143 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 WM46_RS15415 867adb7971072c56b4b5ae4ad9b2e7de 272 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 190 268 1.2E-14 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 WM46_RS15415 867adb7971072c56b4b5ae4ad9b2e7de 272 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 189 267 2.9E-13 T 28-03-2018 IPR006260 TonB, C-terminal GO:0006810 WM46_RS15415 867adb7971072c56b4b5ae4ad9b2e7de 272 Gene3D G3DSA:3.30.1150.10 63 272 2.6E-16 T 28-03-2018 WM46_RS15415 867adb7971072c56b4b5ae4ad9b2e7de 272 SUPERFAMILY SSF74653 183 258 8.37E-14 T 28-03-2018 WM46_RS16225 be8596d5c9df26eb5b2f558dfd6e0056 273 Pfam PF02673 Bacitracin resistance protein BacA 10 266 5.0E-89 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 WM46_RS16225 be8596d5c9df26eb5b2f558dfd6e0056 273 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 265 3.3E-109 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 WM46_RS16225 be8596d5c9df26eb5b2f558dfd6e0056 273 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 272 18.79 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 WM46_RS20415 a27702276768bac370530ba09af948c9 417 SUPERFAMILY SSF53383 16 411 1.28E-58 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS20415 a27702276768bac370530ba09af948c9 417 Gene3D G3DSA:3.40.640.10 69 289 2.4E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS20415 a27702276768bac370530ba09af948c9 417 Gene3D G3DSA:3.90.1150.10 290 407 1.4E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS20415 a27702276768bac370530ba09af948c9 417 Pfam PF00155 Aminotransferase class I and II 70 400 1.6E-19 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 WM46_RS04320 5af2d73000251995396da128f7c68f5b 319 SUPERFAMILY SSF53807 32 317 1.13E-76 T 28-03-2018 WM46_RS04320 5af2d73000251995396da128f7c68f5b 319 Gene3D G3DSA:3.40.50.1980 199 317 6.2E-26 T 28-03-2018 WM46_RS04320 5af2d73000251995396da128f7c68f5b 319 Pfam PF01297 Zinc-uptake complex component A periplasmic 33 315 3.4E-58 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 WM46_RS04320 5af2d73000251995396da128f7c68f5b 319 Gene3D G3DSA:3.40.50.1980 32 198 9.1E-47 T 28-03-2018 WM46_RS10250 2a7710fffdd840c7c6a75844425359cc 359 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 54 256 1.7E-5 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 WM46_RS10250 2a7710fffdd840c7c6a75844425359cc 359 Gene3D G3DSA:3.20.20.80 16 338 5.4E-29 T 28-03-2018 WM46_RS10250 2a7710fffdd840c7c6a75844425359cc 359 SUPERFAMILY SSF51445 16 335 4.01E-42 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily WM46_RS11950 8876201236499abe753c714dd1653fdb 196 Gene3D G3DSA:3.30.460.10 26 193 1.1E-49 T 28-03-2018 WM46_RS11950 8876201236499abe753c714dd1653fdb 196 SUPERFAMILY SSF81301 32 192 4.25E-44 T 28-03-2018 WM46_RS11950 8876201236499abe753c714dd1653fdb 196 Pfam PF04229 GrpB protein 30 188 8.9E-49 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase WM46_RS26170 69383fe8a166af2e62b1c3887157e667 238 SUPERFAMILY SSF52540 1 168 8.63E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS26170 69383fe8a166af2e62b1c3887157e667 238 Gene3D G3DSA:3.40.50.300 34 222 3.2E-6 T 28-03-2018 WM46_RS01060 95087a98b1af0047e53cf2a40efd87cc 299 SUPERFAMILY SSF54909 1 296 6.08E-90 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS01060 95087a98b1af0047e53cf2a40efd87cc 299 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 5 295 5.2E-89 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 WM46_RS01060 95087a98b1af0047e53cf2a40efd87cc 299 Pfam PF04261 Dyp-type peroxidase family 5 295 3.3E-96 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 WM46_RS00485 b7f2ba67bacdd908c6899c7d1bba1523 243 Pfam PF13942 YfhG lipoprotein 48 221 9.0E-77 T 28-03-2018 IPR025262 Quorum-sensing regulator protein G WM46_RS00485 b7f2ba67bacdd908c6899c7d1bba1523 243 ProDom PD117379 LIPOPROTEIN YFHG HELIX ALPHA REGULATOR MEMBRANE TRANSCRIPTIONAL FAMILIIY EBP TWO-COMPONENT 18 221 3.0E-77 T 28-03-2018 WM46_RS11665 7a66876a0d69b0891c90225a1a3fcb0c 362 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 337 2.1E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS11665 7a66876a0d69b0891c90225a1a3fcb0c 362 Gene3D G3DSA:1.10.3470.10 3 343 2.4E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS05580 f10235db6adaac5b130a93ef26f159fb 366 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 2 365 1.7E-123 T 28-03-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 WM46_RS05580 f10235db6adaac5b130a93ef26f159fb 366 Pfam PF01699 Sodium/calcium exchanger protein 223 364 2.7E-8 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM46_RS05580 f10235db6adaac5b130a93ef26f159fb 366 Pfam PF01699 Sodium/calcium exchanger protein 41 190 5.1E-14 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM46_RS25900 533bed141d7c2a8bea73fdf6786e1b62 88 Pfam PF05713 Bacterial mobilisation protein (MobC) 17 57 5.7E-9 T 28-03-2018 IPR008687 Bacterial mobilisation WM46_RS08400 b6ec58c6c5e83952cc1c062b3b0ac91b 235 Gene3D G3DSA:3.40.50.880 6 235 1.2E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS08400 b6ec58c6c5e83952cc1c062b3b0ac91b 235 Pfam PF00117 Glutamine amidotransferase class-I 38 230 5.7E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase WM46_RS08400 b6ec58c6c5e83952cc1c062b3b0ac91b 235 SUPERFAMILY SSF52317 9 234 2.89E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like WM46_RS07030 289fe9b3256db107fd777cb54b065e89 175 Gene3D G3DSA:3.40.630.30 4 175 1.6E-26 T 28-03-2018 WM46_RS07030 289fe9b3256db107fd777cb54b065e89 175 Pfam PF13673 Acetyltransferase (GNAT) domain 62 152 5.8E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 WM46_RS07030 289fe9b3256db107fd777cb54b065e89 175 SUPERFAMILY SSF55729 17 175 1.17E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS16905 ec6c8602655b19191f61171211ef2f15 325 Pfam PF01699 Sodium/calcium exchanger protein 175 317 1.1E-27 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM46_RS16905 ec6c8602655b19191f61171211ef2f15 325 Pfam PF01699 Sodium/calcium exchanger protein 4 144 1.0E-27 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 WM46_RS16905 ec6c8602655b19191f61171211ef2f15 325 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 2 312 8.2E-101 T 28-03-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 WM46_RS04555 06fa7f1205743e9fde82b6fe9f29d328 231 Pfam PF03374 Phage antirepressor protein KilAC domain 122 222 2.5E-26 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 WM46_RS04555 06fa7f1205743e9fde82b6fe9f29d328 231 Pfam PF09669 Phage regulatory protein Rha (Phage_pRha) 13 94 1.4E-18 T 28-03-2018 IPR014054 Bacteriophage regulatory protein, Rha family WM46_RS24755 652234712f24893374c2554d0de1f686 151 Pfam PF05232 Chlorhexidine efflux transporter 77 138 4.6E-21 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter WM46_RS24755 652234712f24893374c2554d0de1f686 151 Pfam PF05232 Chlorhexidine efflux transporter 9 71 1.5E-23 T 28-03-2018 IPR007896 Chlorhexidine efflux transporter WM46_RS21980 2a9c9013a1ec6c6a8704e39b450c1579 84 Pfam PF04193 PQ loop repeat 4 56 1.8E-10 T 28-03-2018 IPR006603 PQ-loop repeat WM46_RS15160 f0af33bd77c46b8708f2e41e44d9c265 235 Pfam PF04474 Protein of unknown function (DUF554) 3 227 1.4E-66 T 28-03-2018 IPR007563 Protein of unknown function DUF554 WM46_RS16995 1cc7b2327346f34a1a2e14526b07d5b1 155 Pfam PF04074 Domain of unknown function (DUF386) 1 149 1.2E-40 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family WM46_RS16995 1cc7b2327346f34a1a2e14526b07d5b1 155 Gene3D G3DSA:2.60.120.370 1 153 6.3E-46 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family WM46_RS16995 1cc7b2327346f34a1a2e14526b07d5b1 155 SUPERFAMILY SSF51197 1 153 3.02E-42 T 28-03-2018 WM46_RS16995 1cc7b2327346f34a1a2e14526b07d5b1 155 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 152 2.6E-56 T 28-03-2018 IPR004375 YhcH/YjgK/YiaL family WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 77 5.6E-30 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 28-03-2018 IPR019812 Hydrogenase assembly chaperone, conserved site WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 Pfam PF01455 HupF/HypC family 1 72 9.3E-26 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 SUPERFAMILY SSF159127 1 76 7.85E-24 T 28-03-2018 WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 9.2E-25 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 63 75 9.2E-25 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 20 36 9.2E-25 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS15910 eed40a118d553eaf926984667b5a9f21 82 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 45 61 9.2E-25 T 28-03-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC WM46_RS02305 901516ba427798d1215c321f38a958e7 189 Gene3D G3DSA:3.90.1720.10 64 189 1.2E-39 T 28-03-2018 WM46_RS02305 901516ba427798d1215c321f38a958e7 189 SUPERFAMILY SSF54001 68 186 2.31E-40 T 28-03-2018 WM46_RS02305 901516ba427798d1215c321f38a958e7 189 Pfam PF00877 NlpC/P60 family 80 184 1.2E-33 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain WM46_RS11045 35a125d29d86fc071c4f1f52bd7c4074 242 Pfam PF06149 Protein of unknown function (DUF969) 7 224 7.0E-89 T 28-03-2018 IPR010374 Protein of unknown function DUF969 WM46_RS09185 0e5e5266cfc4f9a464bd29c231ad78f4 231 SMART SM00382 35 219 2.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS09185 0e5e5266cfc4f9a464bd29c231ad78f4 231 Pfam PF00005 ABC transporter 26 171 5.8E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS09185 0e5e5266cfc4f9a464bd29c231ad78f4 231 SUPERFAMILY SSF52540 1 222 8.59E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09185 0e5e5266cfc4f9a464bd29c231ad78f4 231 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS09185 0e5e5266cfc4f9a464bd29c231ad78f4 231 Gene3D G3DSA:3.40.50.300 7 231 1.9E-67 T 28-03-2018 WM46_RS08945 b6e8200ec86596d4f1fa288f55059ab4 150 Pfam PF07012 Curlin associated repeat 39 73 3.8E-6 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS08945 b6e8200ec86596d4f1fa288f55059ab4 150 Pfam PF07012 Curlin associated repeat 107 140 1.1E-7 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS08945 b6e8200ec86596d4f1fa288f55059ab4 150 Pfam PF07012 Curlin associated repeat 66 95 2.4E-6 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS08945 b6e8200ec86596d4f1fa288f55059ab4 150 Pfam PF07012 Curlin associated repeat 85 118 3.4E-10 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS15705 8f768adc2afcb6f93903ef4c51afc07f 353 Pfam PF04245 37-kD nucleoid-associated bacterial protein 18 337 3.3E-18 T 28-03-2018 IPR007358 Nucleoid-associated protein NdpA GO:0009295 WM46_RS22510 abd83789ba66f85086c3750413c7c278 114 Gene3D G3DSA:3.30.70.100 1 103 2.2E-28 T 28-03-2018 WM46_RS22510 abd83789ba66f85086c3750413c7c278 114 SUPERFAMILY SSF54909 1 100 1.07E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS22510 abd83789ba66f85086c3750413c7c278 114 SMART SM00886 2 98 2.0E-25 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel WM46_RS22510 abd83789ba66f85086c3750413c7c278 114 Pfam PF07876 Stress responsive A/B Barrel Domain 2 97 2.4E-25 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel WM46_RS07780 d7e10d8fd9c29eef1c9d885b4d50e1d1 340 Gene3D G3DSA:1.20.1630.10 10 293 3.0E-40 T 28-03-2018 WM46_RS07780 d7e10d8fd9c29eef1c9d885b4d50e1d1 340 Pfam PF03916 Polysulphide reductase, NrfD 12 289 1.2E-36 T 28-03-2018 IPR005614 NrfD family WM46_RS23905 2ba0615d6ca5ea28e9c05bc8b36ba899 716 Pfam PF02554 Carbon starvation protein CstA 34 405 3.2E-161 T 28-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 WM46_RS23905 2ba0615d6ca5ea28e9c05bc8b36ba899 716 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 486 614 1.8E-34 T 28-03-2018 IPR025299 CstA, C-terminal domain WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 SUPERFAMILY SSF51735 9 239 1.36E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.7E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 238 2.4E-24 T 28-03-2018 WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 Gene3D G3DSA:3.40.50.720 8 240 8.8E-37 T 28-03-2018 WM46_RS07350 69cf62850deafded20a2d2372a271b19 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 WM46_RS22320 3d85d76efd5f3921f15eb9017811ea92 412 Gene3D G3DSA:3.90.1150.10 282 412 1.8E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 WM46_RS22320 3d85d76efd5f3921f15eb9017811ea92 412 PIRSF PIRSF000390 46 412 5.2E-80 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS22320 3d85d76efd5f3921f15eb9017811ea92 412 Gene3D G3DSA:3.40.640.10 5 281 4.1E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 WM46_RS22320 3d85d76efd5f3921f15eb9017811ea92 412 SUPERFAMILY SSF53383 62 412 6.12E-74 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase WM46_RS22320 3d85d76efd5f3921f15eb9017811ea92 412 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 62 401 4.2E-83 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase WM46_RS14910 9afa16bf9da0ead674cc5ffe1042bd29 420 Gene3D G3DSA:1.10.10.660 40 104 1.7E-34 T 28-03-2018 IPR024033 Uncharacterised domain, YlbE WM46_RS14910 9afa16bf9da0ead674cc5ffe1042bd29 420 Gene3D G3DSA:3.90.1700.10 250 413 5.8E-75 T 28-03-2018 WM46_RS14910 9afa16bf9da0ead674cc5ffe1042bd29 420 Gene3D G3DSA:3.90.1710.10 105 247 1.6E-58 T 28-03-2018 WM46_RS14910 9afa16bf9da0ead674cc5ffe1042bd29 420 Pfam PF06545 Protein of unknown function (DUF1116) 87 302 4.2E-98 T 28-03-2018 IPR009499 Protein of unknown function DUF1116 WM46_RS06035 3e712a205ec7f0b71a766df93fb71dac 172 Gene3D G3DSA:2.60.40.1090 1 172 3.2E-16 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS06035 3e712a205ec7f0b71a766df93fb71dac 172 SUPERFAMILY SSF49401 49 172 3.78E-7 T 28-03-2018 IPR008966 Adhesion domain WM46_RS09455 cc8ec1e663694ef8dfa25010c100c7d3 248 Pfam PF13847 Methyltransferase domain 36 156 6.7E-12 T 28-03-2018 IPR025714 Methyltransferase domain WM46_RS09455 cc8ec1e663694ef8dfa25010c100c7d3 248 Gene3D G3DSA:3.40.50.150 1 248 9.3E-42 T 28-03-2018 WM46_RS09455 cc8ec1e663694ef8dfa25010c100c7d3 248 PIRSF PIRSF034653 1 248 4.0E-117 T 28-03-2018 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type WM46_RS09455 cc8ec1e663694ef8dfa25010c100c7d3 248 SUPERFAMILY SSF53335 5 244 3.44E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS22700 93def8dcc733c89f02d596e87a20aca3 115 SUPERFAMILY SSF54913 12 114 2.19E-35 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta WM46_RS22700 93def8dcc733c89f02d596e87a20aca3 115 Gene3D G3DSA:3.30.70.120 7 115 9.1E-38 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal WM46_RS22700 93def8dcc733c89f02d596e87a20aca3 115 Hamap MF_01160 Divalent-cation tolerance protein CutA [cutA]. 9 115 36.851 T 28-03-2018 IPR023700 Divalent cation tolerance protein CutA, Enterobacteria GO:0005507|GO:0005737 WM46_RS22700 93def8dcc733c89f02d596e87a20aca3 115 Pfam PF03091 CutA1 divalent ion tolerance protein 15 112 6.2E-34 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 WM46_RS11970 42ead02a51a7948945b721124272b2e4 257 SUPERFAMILY SSF51735 1 204 3.01E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS11970 42ead02a51a7948945b721124272b2e4 257 Gene3D G3DSA:3.40.50.720 1 220 7.8E-31 T 28-03-2018 WM46_RS11970 42ead02a51a7948945b721124272b2e4 257 Pfam PF13460 NAD(P)H-binding 7 194 1.1E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain WM46_RS24235 07152ba3f3d9f6b50e55b07e01ebb4f7 219 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 216 2.9E-72 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 WM46_RS24235 07152ba3f3d9f6b50e55b07e01ebb4f7 219 Pfam PF03006 Haemolysin-III related 12 209 1.1E-37 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 3 299 5.6E-113 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 Pfam PF00294 pfkB family carbohydrate kinase 2 294 1.1E-64 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 Gene3D G3DSA:3.40.1190.20 1 306 2.4E-76 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 SUPERFAMILY SSF53613 1 302 4.37E-82 T 28-03-2018 IPR029056 Ribokinase-like WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 PRINTS PR00990 Ribokinase signature 32 51 1.7E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 PRINTS PR00990 Ribokinase signature 5 26 1.7E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 PRINTS PR00990 Ribokinase signature 173 188 1.7E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 PRINTS PR00990 Ribokinase signature 104 117 1.7E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 PRINTS PR00990 Ribokinase signature 217 228 1.7E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 WM46_RS19820 b88ee517ff7de006531870bdf4785657 306 Hamap MF_01987 Ribokinase [rbsK]. 1 301 25.548 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 WM46_RS07210 c029188bb94c9bdf911127bb71733e7b 102 ProDom PD336997 PRECURSOR SIGNAL MEMBRANE OUTER YNFD ESCHERICHIA EXPORTED PP0087 COLI PP0090 2 80 6.0E-30 T 28-03-2018 IPR010595 Protein of unknown function DUF1161 WM46_RS07210 c029188bb94c9bdf911127bb71733e7b 102 Pfam PF06649 Protein of unknown function (DUF1161) 27 80 3.1E-22 T 28-03-2018 IPR010595 Protein of unknown function DUF1161 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 Pfam PF00890 FAD binding domain 3 431 3.2E-32 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 SUPERFAMILY SSF56425 234 395 3.84E-24 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 Gene3D G3DSA:3.50.50.60 1 236 2.2E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 SUPERFAMILY SSF51905 394 460 6.49E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 SUPERFAMILY SSF51905 2 230 6.49E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 Gene3D G3DSA:3.90.700.10 254 398 1.3E-28 T 28-03-2018 WM46_RS11180 57f10805598e5c38b5e89a8a82723b5c 467 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 2 460 4.3E-206 T 28-03-2018 IPR012831 Precorrin 3B synthase CobZ WM46_RS05920 c629bb5d47046db364c4df6d81fa51c0 196 Pfam PF00925 GTP cyclohydrolase II 5 170 8.2E-68 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 WM46_RS05920 c629bb5d47046db364c4df6d81fa51c0 196 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 1 196 48.72 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 WM46_RS05920 c629bb5d47046db364c4df6d81fa51c0 196 SUPERFAMILY SSF142695 3 173 4.84E-67 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 WM46_RS05920 c629bb5d47046db364c4df6d81fa51c0 196 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 5 194 3.8E-94 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 WM46_RS09330 3d5832eb825b33f790d11e1f3486f01a 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 346 3.9E-52 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM46_RS09330 3d5832eb825b33f790d11e1f3486f01a 356 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 345 2.1E-88 T 28-03-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 WM46_RS07525 2e9b8755c814c747c97c90ede5bbc5fc 671 Pfam PF04632 Fusaric acid resistance protein family 20 663 2.4E-169 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 WM46_RS02115 88f7a07ac68aac65fb3d2df65d98b825 415 Pfam PF00916 Sulfate permease family 163 348 3.7E-22 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 WM46_RS02115 88f7a07ac68aac65fb3d2df65d98b825 415 Pfam PF00916 Sulfate permease family 30 152 1.5E-16 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 WM46_RS10890 f36788f3e33084319c1736f49e479673 105 Pfam PF14330 Domain of unknown function (DUF4387) 6 102 2.1E-39 T 28-03-2018 IPR025496 Protein of unknown function DUF4387 WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 SUPERFAMILY SSF49354 19 136 3.66E-40 T 28-03-2018 IPR008962 PapD-like WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 96 113 - T 28-03-2018 IPR018046 Pili assembly chaperone, conserved site WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 Gene3D G3DSA:2.60.40.10 24 139 1.6E-36 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 137 3.9E-40 T 28-03-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 PRINTS PR00969 Pili chaperone signature 97 114 4.4E-22 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 PRINTS PR00969 Pili chaperone signature 25 34 4.4E-22 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 PRINTS PR00969 Pili chaperone signature 156 171 4.4E-22 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 PRINTS PR00969 Pili chaperone signature 120 135 4.4E-22 T 28-03-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 SUPERFAMILY SSF49584 143 216 2.88E-17 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 Gene3D G3DSA:2.60.40.10 141 225 3.5E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold WM46_RS12015 a2de9c2351ce9d0c64d1e48360df8fd9 225 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 161 216 9.2E-11 T 28-03-2018 IPR016148 Pili assembly chaperone, C-terminal WM46_RS10675 a28e0d611ed512e8d43f6f5a3dd52bac 331 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 18 322 2.4E-120 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 WM46_RS10675 a28e0d611ed512e8d43f6f5a3dd52bac 331 SUPERFAMILY SSF52540 6 323 5.67E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS10675 a28e0d611ed512e8d43f6f5a3dd52bac 331 Pfam PF03308 ArgK protein 22 290 1.1E-108 T 28-03-2018 WM46_RS10675 a28e0d611ed512e8d43f6f5a3dd52bac 331 Gene3D G3DSA:3.40.50.300 52 262 4.2E-32 T 28-03-2018 WM46_RS10675 a28e0d611ed512e8d43f6f5a3dd52bac 331 Gene3D G3DSA:1.20.5.170 6 50 9.6E-15 T 28-03-2018 WM46_RS10675 a28e0d611ed512e8d43f6f5a3dd52bac 331 Gene3D G3DSA:1.10.287.130 264 325 8.9E-12 T 28-03-2018 WM46_RS01325 872e96c4610c712de50b5979101cbcd7 179 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 5 179 1.8E-59 T 28-03-2018 IPR018636 Protein of unknown function DUF2058 WM46_RS13825 310109205c710535d246eb5b144b4b4d 217 Gene3D G3DSA:1.10.3720.10 1 217 8.9E-40 T 28-03-2018 WM46_RS13825 310109205c710535d246eb5b144b4b4d 217 SUPERFAMILY SSF161098 9 201 8.76E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS13825 310109205c710535d246eb5b144b4b4d 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 212 3.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01805 26e88bb20aa45666ba298fd045b8a027 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 100 19.378 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 WM46_RS01805 26e88bb20aa45666ba298fd045b8a027 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 95 8.1E-21 T 28-03-2018 WM46_RS01690 f7338bcd95c03ad137e1f9fe6726f408 90 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 83 1.1E-16 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS01690 f7338bcd95c03ad137e1f9fe6726f408 90 Gene3D G3DSA:3.40.50.2300 1 90 2.5E-19 T 28-03-2018 WM46_RS01690 f7338bcd95c03ad137e1f9fe6726f408 90 SUPERFAMILY SSF52794 1 85 3.14E-21 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS15665 e75cd9d2494a282da6f88aebb08393ec 156 Pfam PF12101 Protein of unknown function (DUF3577) 10 138 3.4E-58 T 28-03-2018 IPR021960 Protein of unknown function DUF3577 WM46_RS16440 43a973c6a1c0c3b3046c50ab4312b52f 97 Pfam PF13997 YqjK-like protein 14 86 4.9E-28 T 28-03-2018 IPR025612 YqjK-like protein WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PIRSF PIRSF016599 1 485 1.9E-212 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 482 5.6E-183 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 Pfam PF01546 Peptidase family M20/M25/M40 73 480 2.6E-20 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 SUPERFAMILY SSF53187 10 182 1.12E-64 T 28-03-2018 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 SUPERFAMILY SSF53187 397 481 1.12E-64 T 28-03-2018 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 Gene3D G3DSA:3.40.630.10 5 483 1.9E-50 T 28-03-2018 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 Pfam PF07687 Peptidase dimerisation domain 201 293 5.3E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 450 472 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 251 270 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 428 444 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 363 381 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS13675 c986f84c34612c64a500288d10dae68f 485 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 9.2E-103 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 WM46_RS12595 838c64b3876f2aab0e0d65f25b635c45 231 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 206 1.5E-86 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM46_RS12595 838c64b3876f2aab0e0d65f25b635c45 231 Pfam PF06508 Queuosine biosynthesis protein QueC 3 213 7.3E-84 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM46_RS12595 838c64b3876f2aab0e0d65f25b635c45 231 PIRSF PIRSF006293 1 226 1.8E-86 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM46_RS12595 838c64b3876f2aab0e0d65f25b635c45 231 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 219 53.106 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 WM46_RS12595 838c64b3876f2aab0e0d65f25b635c45 231 Gene3D G3DSA:3.40.50.620 1 231 1.3E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS12595 838c64b3876f2aab0e0d65f25b635c45 231 SUPERFAMILY SSF52402 1 219 1.92E-69 T 28-03-2018 WM46_RS03920 a7ffd7dc591ca304e3e8574c0928e3c2 74 Pfam PF10769 Protein of unknown function (DUF2594) 1 74 5.1E-38 T 28-03-2018 WM46_RS10430 837ae56f9766c303a1649ab1aaab5ead 308 SUPERFAMILY SSF53335 43 295 1.67E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase WM46_RS10430 837ae56f9766c303a1649ab1aaab5ead 308 Pfam PF05971 Protein of unknown function (DUF890) 4 296 5.1E-147 T 28-03-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 WM46_RS10430 837ae56f9766c303a1649ab1aaab5ead 308 PIRSF PIRSF029038 1 308 7.1E-145 T 28-03-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 WM46_RS10430 837ae56f9766c303a1649ab1aaab5ead 308 Gene3D G3DSA:3.40.50.150 38 296 2.2E-52 T 28-03-2018 WM46_RS10430 837ae56f9766c303a1649ab1aaab5ead 308 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 5 298 53.178 T 28-03-2018 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 WM46_RS11960 9244098f0dfadbfef5e621bb32d8aa95 329 Pfam PF00248 Aldo/keto reductase family 16 305 4.8E-74 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS11960 9244098f0dfadbfef5e621bb32d8aa95 329 SUPERFAMILY SSF51430 1 312 4.98E-101 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS11960 9244098f0dfadbfef5e621bb32d8aa95 329 Gene3D G3DSA:3.20.20.100 1 327 1.3E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS12870 21205047d4338cd338b4f47ea619ae6a 888 PIRSF PIRSF035905 589 888 7.9E-17 T 28-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein WM46_RS12870 21205047d4338cd338b4f47ea619ae6a 888 PIRSF PIRSF035905 9 600 1.8E-62 T 28-03-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein WM46_RS12870 21205047d4338cd338b4f47ea619ae6a 888 Pfam PF10101 Predicted membrane protein (DUF2339) 138 537 2.1E-105 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane WM46_RS12870 21205047d4338cd338b4f47ea619ae6a 888 Pfam PF10101 Predicted membrane protein (DUF2339) 527 881 4.9E-41 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane WM46_RS06350 859abf30d23144709194aa4eb62c8fe6 264 Gene3D G3DSA:1.10.3620.10 148 252 9.9E-39 T 28-03-2018 WM46_RS06350 859abf30d23144709194aa4eb62c8fe6 264 Pfam PF02698 DUF218 domain 38 171 6.2E-16 T 28-03-2018 IPR003848 Domain of unknown function DUF218 WM46_RS00455 dfed890798f807bc022a280be3e84545 185 Pfam PF14437 MafB19-like deaminase 27 173 3.1E-33 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 WM46_RS00455 dfed890798f807bc022a280be3e84545 185 SUPERFAMILY SSF53927 24 177 6.19E-60 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 WM46_RS00455 dfed890798f807bc022a280be3e84545 185 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 32 173 49.252 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 WM46_RS00455 dfed890798f807bc022a280be3e84545 185 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 77 114 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 WM46_RS00455 dfed890798f807bc022a280be3e84545 185 Gene3D G3DSA:3.40.140.10 22 181 2.4E-53 T 28-03-2018 WM46_RS07815 b0b8f0992f7b2c46578601cff33ce45c 78 Gene3D G3DSA:1.20.5.190 22 73 1.8E-16 T 28-03-2018 WM46_RS07815 b0b8f0992f7b2c46578601cff33ce45c 78 Pfam PF04728 Lipoprotein leucine-zipper 26 78 6.4E-25 T 28-03-2018 IPR006817 Lipoprotein leucine-zipper GO:0019867 WM46_RS07815 b0b8f0992f7b2c46578601cff33ce45c 78 SUPERFAMILY SSF58042 24 74 4.58E-23 T 28-03-2018 WM46_RS07815 b0b8f0992f7b2c46578601cff33ce45c 78 PIRSF PIRSF002855 1 78 1.9E-29 T 28-03-2018 IPR016367 Murein-lipoprotein WM46_RS13245 bb1e216ddd904bd15392bd9f362b6766 104 SUPERFAMILY SSF52794 1 99 5.23E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 WM46_RS13245 bb1e216ddd904bd15392bd9f362b6766 104 Gene3D G3DSA:3.40.50.2300 2 103 2.5E-16 T 28-03-2018 WM46_RS15405 1614998924339ecab8dca14e4f8d4454 322 Pfam PF01618 MotA/TolQ/ExbB proton channel family 187 290 1.2E-34 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 WM46_RS15405 1614998924339ecab8dca14e4f8d4454 322 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 94 302 4.5E-63 T 28-03-2018 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 WM46_RS18785 668f9a472c3a32067f796317d4598655 292 SUPERFAMILY SSF51569 3 288 3.66E-65 T 28-03-2018 WM46_RS18785 668f9a472c3a32067f796317d4598655 292 Hamap MF_01912 Sulfofructosephosphate aldolase. 1 292 65.246 T 28-03-2018 IPR017291 Sulfofructosephosphate aldolase, YihT GO:0061595|GO:1902777 MetaCyc: PWY-7446 WM46_RS18785 668f9a472c3a32067f796317d4598655 292 Gene3D G3DSA:3.20.20.70 1 292 7.6E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 WM46_RS18785 668f9a472c3a32067f796317d4598655 292 SMART SM01133 16 258 9.5E-15 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS18785 668f9a472c3a32067f796317d4598655 292 Pfam PF01791 DeoC/LacD family aldolase 17 257 9.6E-59 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 WM46_RS18785 668f9a472c3a32067f796317d4598655 292 PIRSF PIRSF037840 1 291 1.7E-134 T 28-03-2018 IPR017291 Sulfofructosephosphate aldolase, YihT GO:0061595|GO:1902777 MetaCyc: PWY-7446 WM46_RS11560 0e453f8d4182153d23283dc62f6f534c 65 Pfam PF04328 Selenoprotein, putative 5 65 2.0E-30 T 28-03-2018 IPR007423 Selenoprotein, putative WM46_RS15950 d42a6ab85387190e037a94c022ba0bd1 95 ProDom PD065638 YGHW CYTOPLASMIC STY3323 1 94 2.0E-44 T 28-03-2018 IPR022574 Protein of unknown function DUF2623 WM46_RS15950 d42a6ab85387190e037a94c022ba0bd1 95 Pfam PF11115 Protein of unknown function (DUF2623) 1 92 1.1E-45 T 28-03-2018 IPR022574 Protein of unknown function DUF2623 WM46_RS08560 2273247a2a0250c5f7437281ce286b14 357 Pfam PF01757 Acyltransferase family 7 327 2.8E-21 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 WM46_RS18720 129690c4931c62846fabd81e34360a16 128 Gene3D G3DSA:3.40.50.1010 2 122 2.2E-22 T 28-03-2018 IPR029060 PIN domain-like WM46_RS18720 129690c4931c62846fabd81e34360a16 128 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 119 9.962 T 28-03-2018 IPR022907 VapC family GO:0004540 WM46_RS18720 129690c4931c62846fabd81e34360a16 128 SUPERFAMILY SSF88723 5 120 9.53E-29 T 28-03-2018 IPR029060 PIN domain-like WM46_RS18720 129690c4931c62846fabd81e34360a16 128 Pfam PF01850 PIN domain 6 112 6.5E-18 T 28-03-2018 IPR002716 PIN domain WM46_RS25250 106cb39ccabfd59174b886ae4e8efced 107 ProDom PD070788 MEMBRANE OXIDASE SUBUNIT CYTOCHROME YGBE INNER STY3057 TRANSMEMBRANE 23 107 3.0E-34 T 28-03-2018 IPR022721 Protein of unknown function DUF3561 WM46_RS25250 106cb39ccabfd59174b886ae4e8efced 107 Pfam PF12084 Protein of unknown function (DUF3561) 1 107 7.6E-49 T 28-03-2018 IPR022721 Protein of unknown function DUF3561 WM46_RS18465 f82f46213954dabdb79a369eb1157d0e 490 PIRSF PIRSF002457 3 490 2.6E-125 T 28-03-2018 IPR030676 Citrate carrier CitT-related WM46_RS18465 f82f46213954dabdb79a369eb1157d0e 490 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 27 484 1.8E-105 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS18465 f82f46213954dabdb79a369eb1157d0e 490 Pfam PF00939 Sodium:sulfate symporter transmembrane region 10 490 1.2E-127 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS00835 fc39969ffd4ad7303ec7d8d249b34f0e 354 Pfam PF01594 AI-2E family transporter 20 345 5.6E-83 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like WM46_RS05110 815e8d3f92efc103b58331bea16c06e1 216 SUPERFAMILY SSF50814 31 216 1.71E-74 T 28-03-2018 IPR012674 Calycin WM46_RS05110 815e8d3f92efc103b58331bea16c06e1 216 Gene3D G3DSA:2.40.128.20 29 216 3.7E-67 T 28-03-2018 IPR012674 Calycin WM46_RS05110 815e8d3f92efc103b58331bea16c06e1 216 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 37 216 4.3E-81 T 28-03-2018 IPR015304 ZinT domain GO:0008270 WM46_RS15935 5182d8e93e960961cdf74ab31ad44ee9 392 Pfam PF03916 Polysulphide reductase, NrfD 45 329 2.7E-16 T 28-03-2018 IPR005614 NrfD family WM46_RS15935 5182d8e93e960961cdf74ab31ad44ee9 392 Gene3D G3DSA:1.20.1630.10 41 336 1.8E-41 T 28-03-2018 WM46_RS05145 518b3d17f4cebcd3af7deac67fbb27dc 153 Pfam PF03692 Putative zinc- or iron-chelating domain 29 97 4.7E-8 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein WM46_RS05145 518b3d17f4cebcd3af7deac67fbb27dc 153 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 7 150 41.766 T 28-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 WM46_RS05145 518b3d17f4cebcd3af7deac67fbb27dc 153 PIRSF PIRSF006173 4 150 8.3E-68 T 28-03-2018 IPR008228 Uncharacterised conserved protein UCP006173 WM46_RS07200 5964b7585b187b8c0df8b81f1d51d564 236 Hamap MF_01065 UPF0257 lipoprotein YnfC [ynfC]. 2 236 40.081 T 28-03-2018 IPR010646 Uncharacterised protein family UPF0257 GO:0005886 WM46_RS07200 5964b7585b187b8c0df8b81f1d51d564 236 ProDom PD120112 LIPOPROTEIN YNFC MEMBRANE UPF0257 PRECURSOR PALMITATE SIGNAL INNER 1 236 1.0E-105 T 28-03-2018 IPR010646 Uncharacterised protein family UPF0257 GO:0005886 WM46_RS07200 5964b7585b187b8c0df8b81f1d51d564 236 Pfam PF06788 Uncharacterised protein family (UPF0257) 1 236 7.0E-124 T 28-03-2018 IPR010646 Uncharacterised protein family UPF0257 GO:0005886 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 SUPERFAMILY SSF53850 33 330 7.56E-55 T 28-03-2018 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 Gene3D G3DSA:3.40.190.10 160 328 1.6E-28 T 28-03-2018 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 Pfam PF13416 Bacterial extracellular solute-binding protein 56 327 4.3E-25 T 28-03-2018 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 152 1.9E-6 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 276 295 1.9E-6 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 62 83 1.9E-6 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 WM46_RS06555 2d70666a29103defee887fcc90658da5 381 Gene3D G3DSA:3.40.190.10 30 159 1.5E-16 T 28-03-2018 WM46_RS05045 60fbfc313fc2d295106b0dbc8f2c1564 658 Pfam PF01757 Acyltransferase family 5 309 2.0E-25 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 WM46_RS00865 604659b2c17a1d8ddca2f80a83abd89c 288 Pfam PF04228 Putative neutral zinc metallopeptidase 1 284 2.5E-141 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative WM46_RS09335 0c2602073ac4e5d33503c38dac5f953a 355 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 3 350 3.8E-85 T 28-03-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 WM46_RS09335 0c2602073ac4e5d33503c38dac5f953a 355 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 350 4.2E-51 T 28-03-2018 IPR005495 Permease LptG/LptF-related GO:0016021 WM46_RS09115 01808a46e4ed631725bae2a8fb2f4f3b 277 SUPERFAMILY SSF103473 5 261 3.01E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS09115 01808a46e4ed631725bae2a8fb2f4f3b 277 Pfam PF03239 Iron permease FTR1 family 1 271 5.1E-75 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 WM46_RS09115 01808a46e4ed631725bae2a8fb2f4f3b 277 TIGRFAM TIGR00145 TIGR00145: FTR1 family protein 1 272 3.9E-104 T 28-03-2018 IPR005217 Iron permease FTR1-like GO:0005381|GO:0005886|GO:0006827|GO:0033573 WM46_RS20220 c84e7dbfad7c04804ddb3c794481d29d 423 Pfam PF04932 O-Antigen ligase 203 354 1.9E-11 T 28-03-2018 IPR007016 O-antigen ligase-related WM46_RS15440 fd05308e30e114ca15e2e3da07bbe5fa 378 Pfam PF00578 AhpC/TSA family 37 144 3.1E-8 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS15440 fd05308e30e114ca15e2e3da07bbe5fa 378 Gene3D G3DSA:3.40.30.10 4 161 7.8E-18 T 28-03-2018 WM46_RS15440 fd05308e30e114ca15e2e3da07bbe5fa 378 SUPERFAMILY SSF52833 14 148 1.01E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS15440 fd05308e30e114ca15e2e3da07bbe5fa 378 ProSitePatterns PS00194 Thioredoxin family active site. 45 63 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 WM46_RS03905 51b2f91423e58fdfe0d47f8ef1567f5b 222 Gene3D G3DSA:1.10.3720.10 4 220 3.6E-46 T 28-03-2018 WM46_RS03905 51b2f91423e58fdfe0d47f8ef1567f5b 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 3.9E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS03905 51b2f91423e58fdfe0d47f8ef1567f5b 222 SUPERFAMILY SSF161098 13 200 6.54E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS03905 51b2f91423e58fdfe0d47f8ef1567f5b 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 3.0E-33 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS04640 fbc05a28d7dc7dfd6914d195fdb12209 176 Pfam PF10721 Protein of unknown function (DUF2514) 9 166 5.6E-42 T 28-03-2018 IPR019659 Protein of unknown function DUF2514 WM46_RS05390 833ff67db5afa066c85f41926e80714f 130 Pfam PF10980 Protein of unknown function (DUF2787) 12 126 1.8E-35 T 28-03-2018 IPR021248 Protein of unknown function DUF2787 WM46_RS11555 1d7a4222b054f5a0673335820b6a28eb 205 Pfam PF02195 ParB-like nuclease domain 48 141 4.6E-15 T 28-03-2018 IPR003115 ParB/Sulfiredoxin WM46_RS11555 1d7a4222b054f5a0673335820b6a28eb 205 Gene3D G3DSA:3.90.1530.10 40 146 1.4E-12 T 28-03-2018 WM46_RS11555 1d7a4222b054f5a0673335820b6a28eb 205 SUPERFAMILY SSF110849 45 175 1.05E-25 T 28-03-2018 IPR003115 ParB/Sulfiredoxin WM46_RS11555 1d7a4222b054f5a0673335820b6a28eb 205 SMART SM00470 47 142 4.9E-11 T 28-03-2018 IPR003115 ParB/Sulfiredoxin WM46_RS02495 c8f17d6ef76f42c8e5ba227a4a64d66d 132 Hamap MF_01144 UPF0299 membrane protein YohJ [yohJ]. 4 123 23.597 T 28-03-2018 IPR022957 Uncharacterised protein family UPF0299 WM46_RS02495 c8f17d6ef76f42c8e5ba227a4a64d66d 132 Pfam PF03788 LrgA family 23 113 7.0E-28 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 WM46_RS06095 af8b99f3fd8c1cc48ed3bc2edcce60f2 231 Gene3D G3DSA:3.40.50.1820 8 231 1.4E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06095 af8b99f3fd8c1cc48ed3bc2edcce60f2 231 SUPERFAMILY SSF53474 6 229 3.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS06095 af8b99f3fd8c1cc48ed3bc2edcce60f2 231 Pfam PF12697 Alpha/beta hydrolase family 28 166 4.6E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS02955 18a115550f92f6ec92b1d8cce15c6589 156 Gene3D G3DSA:2.160.10.10 1 154 1.9E-30 T 28-03-2018 WM46_RS02955 18a115550f92f6ec92b1d8cce15c6589 156 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 88 120 2.7E-10 T 28-03-2018 IPR001451 Hexapeptide repeat WM46_RS02955 18a115550f92f6ec92b1d8cce15c6589 156 SUPERFAMILY SSF51161 20 144 2.22E-31 T 28-03-2018 IPR011004 Trimeric LpxA-like WM46_RS04565 bad5540c197fe552fb6bd5f8a65f4afe 228 Pfam PF06992 Replication protein P 1 196 4.5E-67 T 28-03-2018 IPR009731 Replication P GO:0006270 WM46_RS23050 09cfaf0a967fc9386013693d7645c748 126 SUPERFAMILY SSF46785 14 118 6.27E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS23050 09cfaf0a967fc9386013693d7645c748 126 Pfam PF01638 HxlR-like helix-turn-helix 29 116 2.6E-32 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type WM46_RS23050 09cfaf0a967fc9386013693d7645c748 126 Gene3D G3DSA:1.10.10.10 1 126 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 SMART SM00079 22 243 9.4E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 2 241 7.6E-92 T 28-03-2018 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter GO:0006810|GO:0030288 WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 Gene3D G3DSA:3.40.190.10 14 142 1.1E-35 T 28-03-2018 WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 45 58 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 23 242 6.6E-67 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 SUPERFAMILY SSF53850 1 242 8.69E-72 T 28-03-2018 WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 Gene3D G3DSA:3.40.190.10 143 243 1.7E-17 T 28-03-2018 WM46_RS10115 e6d28a6e7cc75a3b77e561334f3a6265 243 SMART SM00062 22 243 2.5E-85 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF WM46_RS02410 ef1808145ad504649ff4d9b6f06b4e49 349 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 14 348 8.5E-161 T 28-03-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 WM46_RS02410 ef1808145ad504649ff4d9b6f06b4e49 349 Pfam PF03601 Conserved hypothetical protein 698 18 326 8.9E-114 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 WM46_RS02445 2a5b9b0f8f1decae2da714f2223ab111 385 Pfam PF04235 Protein of unknown function (DUF418) 215 374 3.3E-44 T 28-03-2018 IPR007349 Domain of unknown function DUF418 WM46_RS08110 00f1bfe5a43d6b44e020ae982ea6ffe7 84 Pfam PF10729 Cell division activator CedA 6 82 2.0E-47 T 28-03-2018 IPR019666 Cell division activator CedA GO:0003677|GO:0051301 WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 114 138 - T 28-03-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 28 150 30.045 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 SUPERFAMILY SSF57716 111 149 4.56E-10 T 28-03-2018 WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 32 140 1.5E-51 T 28-03-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 SUPERFAMILY SSF109635 9 109 3.01E-37 T 28-03-2018 WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 110 143 2.4E-10 T 28-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 PRINTS PR00618 DksA/TraR zinc finger signature 126 138 9.9E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria WM46_RS14090 58eca3e6eb1f7d413173c829f86adbf7 151 PRINTS PR00618 DksA/TraR zinc finger signature 114 125 9.9E-5 T 28-03-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria WM46_RS01840 2743e18749dfd4a780aa68ccadb0c849 101 Pfam PF05957 Bacterial protein of unknown function (DUF883) 9 101 6.3E-30 T 28-03-2018 IPR010279 Protein of unknown function DUF883, ElaB WM46_RS22980 c3b16e45055dfd823066fa56b3af0161 254 Pfam PF01925 Sulfite exporter TauE/SafE 15 249 2.6E-39 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 WM46_RS06810 b4b8e73d6b631684c34b0ab8655da5a5 92 Gene3D G3DSA:3.30.2310.20 1 92 8.8E-27 T 28-03-2018 WM46_RS06810 b4b8e73d6b631684c34b0ab8655da5a5 92 SUPERFAMILY SSF143011 1 92 4.05E-16 T 28-03-2018 IPR035095 Toxin RelE-like domain WM46_RS06810 b4b8e73d6b631684c34b0ab8655da5a5 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 92 7.7E-23 T 28-03-2018 IPR007711 Toxin HigB-1 WM46_RS03805 c4c353803d9799e1555502c7eadeca3b 154 Pfam PF03748 Flagellar basal body-associated protein FliL 56 152 1.0E-19 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 WM46_RS06260 c1c7a2a4aa0c5e04d0be81cac427cca1 70 Pfam PF13619 KTSC domain 7 64 1.3E-21 T 28-03-2018 IPR025309 KTSC domain WM46_RS01590 61e80d8cf8a6279e34c942f396fd63bb 229 Gene3D G3DSA:3.30.70.1070 147 226 9.7E-9 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS01590 61e80d8cf8a6279e34c942f396fd63bb 229 SUPERFAMILY SSF110997 149 226 1.05E-12 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS01590 61e80d8cf8a6279e34c942f396fd63bb 229 Pfam PF05036 Sporulation related domain 150 223 9.7E-11 T 28-03-2018 IPR007730 Sporulation-related domain GO:0042834 WM46_RS01590 61e80d8cf8a6279e34c942f396fd63bb 229 Hamap MF_02022 Cell division protein DedD [dedD]. 10 228 24.996 T 28-03-2018 IPR032898 Cell division protein DedD GO:0030428|GO:0032506 WM46_RS01655 30802bb2803cc646970a1046701f6015 120 TIGRFAM TIGR00526 folB_dom: FolB domain 7 120 3.8E-38 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS01655 30802bb2803cc646970a1046701f6015 120 SMART SM00905 8 118 2.9E-31 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS01655 30802bb2803cc646970a1046701f6015 120 Gene3D G3DSA:3.30.1130.10 1 120 6.6E-29 T 28-03-2018 WM46_RS01655 30802bb2803cc646970a1046701f6015 120 SUPERFAMILY SSF55620 7 120 7.78E-30 T 28-03-2018 WM46_RS01655 30802bb2803cc646970a1046701f6015 120 Pfam PF02152 Dihydroneopterin aldolase 8 116 1.0E-23 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 WM46_RS08810 6d8ebddbc4809dbfb90a990549e4195e 140 SUPERFAMILY SSF140566 1 113 9.15E-15 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 WM46_RS08810 6d8ebddbc4809dbfb90a990549e4195e 140 Pfam PF05130 FlgN protein 1 129 9.7E-19 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 WM46_RS08810 6d8ebddbc4809dbfb90a990549e4195e 140 Gene3D G3DSA:1.20.58.300 1 114 9.0E-19 T 28-03-2018 WM46_RS10520 e1020f85b8db695f04916c7dcdf989da 253 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 33 244 4.6E-15 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS10520 e1020f85b8db695f04916c7dcdf989da 253 SUPERFAMILY SSF56219 7 251 2.75E-53 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS10520 e1020f85b8db695f04916c7dcdf989da 253 Gene3D G3DSA:3.60.10.10 1 252 5.6E-35 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase WM46_RS23925 7bd376fe9cad8bbc73cbd73aff3e8cc2 423 PIRSF PIRSF006066 1 423 8.5E-123 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 WM46_RS23925 7bd376fe9cad8bbc73cbd73aff3e8cc2 423 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 418 7.0E-108 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit WM46_RS23925 7bd376fe9cad8bbc73cbd73aff3e8cc2 423 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 23 422 1.3E-119 T 28-03-2018 IPR004681 TRAP transporter permease protein GO:0016021 WM46_RS05585 dab9acc7f049ec2d8cea56bfca32b28a 76 SUPERFAMILY SSF140376 2 75 8.63E-28 T 28-03-2018 WM46_RS05585 dab9acc7f049ec2d8cea56bfca32b28a 76 Pfam PF06150 ChaB 9 75 2.9E-27 T 28-03-2018 IPR009317 ChaB WM46_RS03070 93e2177b858f563e39a7e3295490ad50 352 Pfam PF04143 Sulphur transport 21 331 7.7E-102 T 28-03-2018 IPR007272 Sulphur transport domain WM46_RS10415 0982e8bd280f66da10dff27e84f3d6ad 219 Gene3D G3DSA:1.10.3720.10 1 218 2.1E-42 T 28-03-2018 WM46_RS10415 0982e8bd280f66da10dff27e84f3d6ad 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 111 2.8E-30 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS10415 0982e8bd280f66da10dff27e84f3d6ad 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 1.6E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS10415 0982e8bd280f66da10dff27e84f3d6ad 219 SUPERFAMILY SSF161098 13 202 5.49E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS01455 52652f2d2a5cc73d3cdc0a881eaf727a 313 Pfam PF01226 Formate/nitrite transporter 43 279 2.0E-39 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 WM46_RS01455 52652f2d2a5cc73d3cdc0a881eaf727a 313 Gene3D G3DSA:1.20.1080.10 34 295 2.6E-49 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 WM46_RS02905 998172f560e585abb494d99ab7354692 305 SUPERFAMILY SSF53448 4 261 4.02E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02905 998172f560e585abb494d99ab7354692 305 Pfam PF00535 Glycosyl transferase family 2 7 108 1.0E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS02905 998172f560e585abb494d99ab7354692 305 Gene3D G3DSA:3.90.550.10 2 298 8.3E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS19145 749be82c5e87201578261103b5c56523 246 SUPERFAMILY SSF69618 1 245 1.1E-52 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19145 749be82c5e87201578261103b5c56523 246 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 242 1.4E-39 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 WM46_RS19145 749be82c5e87201578261103b5c56523 246 Gene3D G3DSA:3.40.50.10090 35 140 5.5E-20 T 28-03-2018 WM46_RS19145 749be82c5e87201578261103b5c56523 246 Gene3D G3DSA:3.40.50.10090 141 246 1.1E-20 T 28-03-2018 WM46_RS22750 69026d02f49cf2685246e04ed82217b4 288 Pfam PF15922 YjeJ-like 1 281 1.1E-140 T 28-03-2018 IPR031810 YjeJ-like WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 SUPERFAMILY SSF52210 339 494 1.57E-10 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 Gene3D G3DSA:3.40.50.720 61 174 7.3E-6 T 28-03-2018 WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 Gene3D G3DSA:3.40.50.261 192 328 1.4E-16 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 Pfam PF02629 CoA binding domain 194 287 2.3E-11 T 28-03-2018 IPR003781 CoA-binding GO:0048037 WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 SUPERFAMILY SSF52210 187 320 1.7E-17 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 Gene3D G3DSA:3.40.50.261 329 502 1.5E-9 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS14915 8f03c5b0f88de4ff71b634d135daddab 553 Pfam PF00549 CoA-ligase 336 488 3.1E-51 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 WM46_RS18245 164119ca0246328084afce316ecd5190 240 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 23 238 9.3E-67 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal WM46_RS09180 e8501eb69c4dbca5c4e514132cb2cd4a 184 Gene3D G3DSA:3.40.30.10 42 183 1.2E-27 T 28-03-2018 WM46_RS09180 e8501eb69c4dbca5c4e514132cb2cd4a 184 SUPERFAMILY SSF52833 46 182 1.14E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS09180 e8501eb69c4dbca5c4e514132cb2cd4a 184 Pfam PF00578 AhpC/TSA family 48 161 3.0E-14 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 WM46_RS12340 d30e8b162fcd30e011f7a481637c930a 406 Pfam PF07690 Major Facilitator Superfamily 31 363 5.6E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS12340 d30e8b162fcd30e011f7a481637c930a 406 SUPERFAMILY SSF103473 17 401 2.62E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS12340 d30e8b162fcd30e011f7a481637c930a 406 Gene3D G3DSA:1.20.1250.20 217 405 2.5E-25 T 28-03-2018 WM46_RS12340 d30e8b162fcd30e011f7a481637c930a 406 Gene3D G3DSA:1.20.1250.20 20 214 1.2E-19 T 28-03-2018 WM46_RS09675 81fb2f624f52bb63060f36dedfa49650 546 Pfam PF02470 MlaD protein 42 133 1.5E-9 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS09675 81fb2f624f52bb63060f36dedfa49650 546 Pfam PF02470 MlaD protein 286 389 5.9E-13 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS09675 81fb2f624f52bb63060f36dedfa49650 546 Pfam PF02470 MlaD protein 157 222 1.9E-8 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS09675 81fb2f624f52bb63060f36dedfa49650 546 Gene3D G3DSA:1.20.120.570 402 535 1.2E-4 T 28-03-2018 WM46_RS18910 5cab1dba50421dfc229813b070a76c93 167 Gene3D G3DSA:3.40.50.300 1 166 1.5E-29 T 28-03-2018 WM46_RS18910 5cab1dba50421dfc229813b070a76c93 167 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 164 3.0E-50 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 WM46_RS18910 5cab1dba50421dfc229813b070a76c93 167 SUPERFAMILY SSF52540 2 164 2.49E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS18910 5cab1dba50421dfc229813b070a76c93 167 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 5 139 5.0E-49 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 WM46_RS12225 c2f775eca465ecc25afeaf0edf8682db 313 Pfam PF08902 Domain of unknown function (DUF1848) 2 270 8.6E-103 T 28-03-2018 IPR014998 Protein of unknown function DUF1848 WM46_RS25675 60d2b9f16476c85af2ce22b40922c07c 114 SUPERFAMILY SSF159894 1 111 1.7E-59 T 28-03-2018 WM46_RS25675 60d2b9f16476c85af2ce22b40922c07c 114 Pfam PF09400 Protein of unknown function (DUF2002) 1 110 7.6E-60 T 28-03-2018 IPR018994 Protein of unknown function DUF2002 WM46_RS21390 f4a5a0e128f6b8120611054b2730e16e 97 Pfam PF07362 Post-segregation antitoxin CcdA 62 97 3.9E-6 T 28-03-2018 IPR009956 Post-segregation antitoxin CcdA WM46_RS21710 f2f0366efa10752638c89511104299ee 222 SUPERFAMILY SSF47616 81 214 2.09E-23 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like WM46_RS21710 f2f0366efa10752638c89511104299ee 222 Pfam PF00043 Glutathione S-transferase, C-terminal domain 139 205 3.7E-8 T 28-03-2018 IPR004046 Glutathione S-transferase, C-terminal WM46_RS21710 f2f0366efa10752638c89511104299ee 222 SUPERFAMILY SSF52833 1 80 8.36E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS21710 f2f0366efa10752638c89511104299ee 222 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 73 2.2E-17 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 WM46_RS21710 f2f0366efa10752638c89511104299ee 222 Gene3D G3DSA:1.20.1050.10 98 216 2.8E-25 T 28-03-2018 WM46_RS21710 f2f0366efa10752638c89511104299ee 222 Gene3D G3DSA:3.40.30.10 1 97 7.0E-26 T 28-03-2018 WM46_RS24540 4ff15e81bc2a055908ab4ae79a4ced1c 432 PIRSF PIRSF004539 1 432 1.0E-129 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS24540 4ff15e81bc2a055908ab4ae79a4ced1c 432 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 6 432 2.0E-127 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS24540 4ff15e81bc2a055908ab4ae79a4ced1c 432 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 6 360 3.9E-120 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 WM46_RS04600 ea3a2697f9eab877b0daa1d4c7de861b 192 Pfam PF04447 Protein of unknown function (DUF550) 28 122 2.0E-42 T 28-03-2018 IPR007538 Domain of unknown function DUF550 WM46_RS04600 ea3a2697f9eab877b0daa1d4c7de861b 192 Pfam PF04448 Protein of unknown function (DUF551) 130 187 4.6E-8 T 28-03-2018 IPR007539 Domain of unknown function DUF551 WM46_RS18300 a081a8b441148b7443657844d8d373b4 189 Pfam PF11659 Protein of unknown function (DUF3261) 50 186 6.2E-38 T 28-03-2018 IPR021675 Protein of unknown function DUF3261 WM46_RS07865 c3b66990344eac77f3eb82077ff719e2 72 Pfam PF15930 Domain of unknown function 11 72 1.5E-39 T 28-03-2018 IPR031830 Uncharacterised protein YdiH WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 9.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 9.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 Gene3D G3DSA:1.10.357.10 69 190 2.0E-11 T 28-03-2018 WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 SUPERFAMILY SSF46689 4 69 5.13E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 51 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 Gene3D G3DSA:1.10.10.60 4 68 2.6E-14 T 28-03-2018 WM46_RS06755 df6c4cf8d62f73926244ef19c494fa60 192 SUPERFAMILY SSF48498 86 186 1.99E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS12905 3ef8772ecb6f65d028b62eb151a1577d 439 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 415 4.1E-163 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 WM46_RS12905 3ef8772ecb6f65d028b62eb151a1577d 439 Pfam PF05525 Branched-chain amino acid transport protein 7 429 1.5E-160 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 WM46_RS03555 bee5f5f46ab20397647c6f66acffe27c 210 SUPERFAMILY SSF63965 9 207 3.66E-63 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 WM46_RS03555 bee5f5f46ab20397647c6f66acffe27c 210 Pfam PF02570 Precorrin-8X methylmutase 10 204 1.8E-66 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 WM46_RS03555 bee5f5f46ab20397647c6f66acffe27c 210 Gene3D G3DSA:3.40.50.10230 3 210 1.6E-74 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 WM46_RS05815 8dc415004df9cac6a7bdebbe32df7de5 212 Gene3D G3DSA:2.40.160.20 22 212 4.9E-33 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS05815 8dc415004df9cac6a7bdebbe32df7de5 212 SUPERFAMILY SSF56925 23 212 4.45E-26 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 WM46_RS05815 8dc415004df9cac6a7bdebbe32df7de5 212 Pfam PF03922 OmpW family 23 212 4.4E-71 T 28-03-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 WM46_RS07325 fa4c8eff64ab90a98796d6b6ca4ecb75 344 Pfam PF01594 AI-2E family transporter 14 327 2.6E-69 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like WM46_RS01335 46f37e797670f9ec91748dcb3f469b8c 160 Gene3D G3DSA:2.40.50.140 1 72 6.4E-15 T 28-03-2018 WM46_RS01335 46f37e797670f9ec91748dcb3f469b8c 160 Pfam PF00313 'Cold-shock' DNA-binding domain 4 64 1.9E-9 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 WM46_RS01335 46f37e797670f9ec91748dcb3f469b8c 160 SUPERFAMILY SSF50249 3 64 8.32E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold WM46_RS15545 9b478c27132060903c717fb6d7e3bcc4 336 Pfam PF01548 Transposase 6 145 2.1E-10 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 WM46_RS15545 9b478c27132060903c717fb6d7e3bcc4 336 Pfam PF02371 Transposase IS116/IS110/IS902 family 211 287 5.9E-20 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 WM46_RS22175 27890aadb15f4d0f0572b7ad02c675b5 294 SUPERFAMILY SSF52540 4 258 1.89E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS22175 27890aadb15f4d0f0572b7ad02c675b5 294 Pfam PF13614 AAA domain 5 155 2.7E-16 T 28-03-2018 IPR025669 AAA domain WM46_RS22175 27890aadb15f4d0f0572b7ad02c675b5 294 Gene3D G3DSA:3.40.50.300 4 292 1.8E-33 T 28-03-2018 WM46_RS12250 05f0afc67bf3878a5c15d9240e4a8045 377 SUPERFAMILY SSF56935 44 377 3.4E-29 T 28-03-2018 WM46_RS12250 05f0afc67bf3878a5c15d9240e4a8045 377 Gene3D G3DSA:2.40.160.10 7 377 6.1E-32 T 28-03-2018 WM46_RS01685 3467ceb30a237b3db1049f1dcd1c583e 147 Gene3D G3DSA:3.40.930.10 1 146 5.1E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS01685 3467ceb30a237b3db1049f1dcd1c583e 147 SUPERFAMILY SSF55804 2 146 8.5E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 WM46_RS01685 3467ceb30a237b3db1049f1dcd1c583e 147 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 145 4.5E-35 T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS01685 3467ceb30a237b3db1049f1dcd1c583e 147 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain WM46_RS03765 4e2f13f24f326e9801dca7377d62f6d0 113 Pfam PF10781 Dextransucrase DSRB 52 110 3.8E-35 T 28-03-2018 IPR019717 Dextransucrase DSRB WM46_RS03765 4e2f13f24f326e9801dca7377d62f6d0 113 Hamap MF_01549 Protein DsrB [dsrB]. 52 113 29.382 T 28-03-2018 IPR019717 Dextransucrase DSRB WM46_RS22770 c2fefe050a33b5eec9288e5ae3611c55 48 Pfam PF08085 Entericidin EcnA/B family 23 43 9.6E-9 T 28-03-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 WM46_RS04850 39525ae7882798264c411daf5e24dbe3 79 Pfam PF07351 Protein of unknown function (DUF1480) 1 78 4.6E-40 T 28-03-2018 IPR009950 Protein of unknown function DUF1480 WM46_RS04850 39525ae7882798264c411daf5e24dbe3 79 ProDom PD060427 YEBV CYTOPLASMIC Y1856 ESCHERICHIA ECS2546 YPO1694 COLI STY1982 SIMILAR 2 79 2.0E-38 T 28-03-2018 IPR009950 Protein of unknown function DUF1480 WM46_RS00065 cf9da5bf431880fdfc545b1a8cca2f97 90 TIGRFAM TIGR03976 chp_LLNDYxLRE: His-Xaa-Ser system protein HxsD 6 88 5.4E-27 T 28-03-2018 IPR023974 His-Xaa-Ser system protein HxsD WM46_RS09190 5d081afb7c5257b3813f9a875ffd710c 376 Gene3D G3DSA:1.20.1250.20 6 366 8.5E-5 T 28-03-2018 WM46_RS09190 5d081afb7c5257b3813f9a875ffd710c 376 Pfam PF02687 FtsX-like permease family 281 369 6.1E-12 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 WM46_RS09190 5d081afb7c5257b3813f9a875ffd710c 376 Pfam PF12704 MacB-like periplasmic core domain 28 192 3.7E-11 T 28-03-2018 IPR025857 MacB-like periplasmic core domain WM46_RS18695 b01ada50c374ffbdadfb99f9dc2eaf0c 211 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 7 204 2.3E-66 T 28-03-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 WM46_RS18695 b01ada50c374ffbdadfb99f9dc2eaf0c 211 Gene3D G3DSA:1.20.950.20 1 211 1.9E-54 T 28-03-2018 WM46_RS18695 b01ada50c374ffbdadfb99f9dc2eaf0c 211 SUPERFAMILY SSF81342 4 206 7.14E-56 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 WM46_RS18695 b01ada50c374ffbdadfb99f9dc2eaf0c 211 Pfam PF01292 Prokaryotic cytochrome b561 9 184 2.2E-22 T 28-03-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 WM46_RS17345 9272f6b906f2d6944efb07f13be09b16 85 Pfam PF07369 Protein of unknown function (DUF1488) 5 84 6.0E-29 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 WM46_RS17345 9272f6b906f2d6944efb07f13be09b16 85 SUPERFAMILY SSF160272 1 84 5.75E-32 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 WM46_RS17345 9272f6b906f2d6944efb07f13be09b16 85 Gene3D G3DSA:3.30.160.140 5 83 1.2E-31 T 28-03-2018 IPR009962 Protein of unknown function DUF1488 WM46_RS24690 6a16af222c31061381e73749fe4d0c98 90 Gene3D G3DSA:3.40.630.30 2 90 1.1E-14 T 28-03-2018 WM46_RS24690 6a16af222c31061381e73749fe4d0c98 90 Pfam PF14542 GCN5-related N-acetyl-transferase 9 88 7.9E-22 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase WM46_RS24690 6a16af222c31061381e73749fe4d0c98 90 SUPERFAMILY SSF55729 4 88 1.49E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase WM46_RS14835 73e1a4d734ced210ba3c3f940f73a60c 455 PIRSF PIRSF004548 1 452 9.1E-177 T 28-03-2018 IPR010364 Uncharacterised protein family, inner membrane CreD WM46_RS14835 73e1a4d734ced210ba3c3f940f73a60c 455 Pfam PF06123 Inner membrane protein CreD 6 427 2.2E-142 T 28-03-2018 IPR010364 Uncharacterised protein family, inner membrane CreD WM46_RS10210 d4691f57e5e3d1d0fe8beb00cbebacab 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 WM46_RS10210 d4691f57e5e3d1d0fe8beb00cbebacab 179 SUPERFAMILY SSF46689 2 81 4.16E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 WM46_RS10210 d4691f57e5e3d1d0fe8beb00cbebacab 179 SUPERFAMILY SSF48498 98 176 9.49E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal WM46_RS10210 d4691f57e5e3d1d0fe8beb00cbebacab 179 Gene3D G3DSA:1.10.357.10 1 179 1.4E-35 T 28-03-2018 WM46_RS04450 1710be8b87b99caffb11dce89d2bdece 63 Pfam PF07131 Protein of unknown function (DUF1382) 1 59 5.3E-21 T 28-03-2018 IPR009814 Bacteriophage lambda, Xis (Q38267) WM46_RS01425 90af24604a436590099479ad7615bfec 83 Pfam PF12674 Putative zinc ribbon domain 7 77 1.8E-6 T 28-03-2018 IPR025868 Putative zinc ribbon domain WM46_RS15770 ab69e564489ad9e3435c6a6b96f0a718 110 Pfam PF04634 Protein of unknown function, DUF600 6 110 9.7E-6 T 28-03-2018 IPR006728 Protein of unknown function DUF600 WM46_RS15770 ab69e564489ad9e3435c6a6b96f0a718 110 SUPERFAMILY SSF160424 5 110 1.57E-15 T 28-03-2018 IPR006728 Protein of unknown function DUF600 WM46_RS15770 ab69e564489ad9e3435c6a6b96f0a718 110 Gene3D G3DSA:3.30.500.20 4 109 3.1E-19 T 28-03-2018 WM46_RS03090 660ac39199fc117e7ef82d9980aa5b39 63 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 6 53 2.9E-4 T 28-03-2018 IPR010260 DNA-binding transcriptional activator AlpA WM46_RS22005 92fdba9957ab405459ff6e4b8f1de567 316 Pfam PF03824 High-affinity nickel-transport protein 201 300 1.3E-7 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 WM46_RS22005 92fdba9957ab405459ff6e4b8f1de567 316 Pfam PF03824 High-affinity nickel-transport protein 68 169 1.5E-16 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 WM46_RS10965 c16deee6ae71fa9993fac80b70f2a6c1 218 Gene3D G3DSA:3.40.50.1860 4 110 9.5E-5 T 28-03-2018 WM46_RS10965 c16deee6ae71fa9993fac80b70f2a6c1 218 Gene3D G3DSA:3.40.50.1860 111 202 1.3E-4 T 28-03-2018 WM46_RS25750 87af91f061d3847a9c2d68f1680612c9 504 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 440 7.1E-144 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 SUPERFAMILY SSF52540 5 253 5.89E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 Pfam PF00005 ABC transporter 25 184 9.4E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 Gene3D G3DSA:3.40.50.300 2 324 4.4E-70 T 28-03-2018 WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 SMART SM00382 34 234 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 4.6E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS06840 7f6d6fd11cca9937c2dc1fdda2b6d01e 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 320 6.1E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 WM46_RS04155 6d21e0ded1224595759b080994a97bce 796 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 279 289 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site WM46_RS04155 6d21e0ded1224595759b080994a97bce 796 Pfam PF00577 Outer membrane usher protein 228 698 1.3E-33 T 28-03-2018 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 WM46_RS06590 47417400495540ab6005976cf629a4fa 57 Pfam PF10753 Toxin GhoT_OrtT 4 57 2.1E-27 T 28-03-2018 IPR019689 Toxin GhoT/OrtT WM46_RS23930 39672a588f4183f02d78a0a7c7c502af 157 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 19 148 3.2E-28 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component WM46_RS11085 d50a5dc860f9c09af02838e3827e8e44 68 Pfam PF10725 Protein of unknown function (DUF2517) 4 63 1.1E-36 T 28-03-2018 IPR019663 Uncharacterised protein YbfA WM46_RS16640 04207eb93df5b4820f4abac4bef30791 268 TIGRFAM TIGR00822 EII-Sor: PTS system, mannose/fructose/sorbose family, IIC component 2 267 6.5E-116 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS16640 04207eb93df5b4820f4abac4bef30791 268 Pfam PF03609 PTS system sorbose-specific iic component 7 238 3.2E-65 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS25430 1c7efb9436e91af5a2afce94dfaaa8e0 83 Gene3D G3DSA:2.10.260.10 28 82 7.1E-4 T 28-03-2018 WM46_RS25430 1c7efb9436e91af5a2afce94dfaaa8e0 83 Pfam PF08845 Toxin SymE, type I toxin-antitoxin system 16 75 1.0E-17 T 28-03-2018 IPR014944 Toxin SymE-like GO:0003723|GO:0005737|GO:0016070|GO:0016788 WM46_RS02510 4f1ac0162a9710c070971c52fbe02d5a 345 Pfam PF07883 Cupin domain 263 325 1.1E-6 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS02510 4f1ac0162a9710c070971c52fbe02d5a 345 Pfam PF07883 Cupin domain 94 162 1.9E-25 T 28-03-2018 IPR013096 Cupin 2, conserved barrel WM46_RS02510 4f1ac0162a9710c070971c52fbe02d5a 345 SUPERFAMILY SSF51182 11 343 4.28E-113 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS02510 4f1ac0162a9710c070971c52fbe02d5a 345 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 11 344 5.7E-182 T 28-03-2018 IPR011960 Gentisate 1,2-dioxygenase WM46_RS02510 4f1ac0162a9710c070971c52fbe02d5a 345 Gene3D G3DSA:2.60.120.10 58 345 5.9E-39 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS04775 aeaaf72a4ba286188d70bdbeed8fb90e 199 Pfam PF06805 Bacteriophage lambda tail assembly protein I 6 58 1.4E-7 T 28-03-2018 IPR010654 Bacteriophage lambda tail assembly I WM46_RS25280 c1aa7013f9d0a18ceb116b532b319dda 253 Gene3D G3DSA:3.40.1210.10 1 247 8.2E-83 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM46_RS25280 c1aa7013f9d0a18ceb116b532b319dda 253 Pfam PF01975 Survival protein SurE 3 180 3.7E-57 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM46_RS25280 c1aa7013f9d0a18ceb116b532b319dda 253 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 249 40.332 T 28-03-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM46_RS25280 c1aa7013f9d0a18ceb116b532b319dda 253 SUPERFAMILY SSF64167 1 246 3.92E-83 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM46_RS25280 c1aa7013f9d0a18ceb116b532b319dda 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 3.6E-79 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 WM46_RS15030 efb3efe2677c7ebe474697e7fc6ce957 106 ProDom PD060540 YQGD INNER MEMBRANE ECS3817 13 82 8.0E-23 T 28-03-2018 IPR020263 Uncharacterised protein family YqgD WM46_RS15030 efb3efe2677c7ebe474697e7fc6ce957 106 Pfam PF10885 Protein of unknown function (DUF2684) 12 91 8.1E-28 T 28-03-2018 IPR020263 Uncharacterised protein family YqgD WM46_RS21650 bb98d333d79c3a2f3ca14ff81c846326 237 TIGRFAM TIGR01672 AphA: HAD phosphatase, family IIIB 1 237 2.1E-120 T 28-03-2018 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 WM46_RS21650 bb98d333d79c3a2f3ca14ff81c846326 237 Gene3D G3DSA:3.40.50.1000 27 237 1.8E-41 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21650 bb98d333d79c3a2f3ca14ff81c846326 237 SUPERFAMILY SSF56784 31 237 6.16E-75 T 28-03-2018 IPR023214 HAD-like domain WM46_RS21650 bb98d333d79c3a2f3ca14ff81c846326 237 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 12 220 1.1E-48 T 28-03-2018 IPR005519 Acid phosphatase, class B-like WM46_RS21650 bb98d333d79c3a2f3ca14ff81c846326 237 PIRSF PIRSF017818 1 237 9.1E-121 T 28-03-2018 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00740+3.1.3.2|MetaCyc: PWY-6348 WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 Hamap MF_00018 UPF0758 protein YicR [yicR]. 1 221 52.116 T 28-03-2018 IPR022820 Uncharacterised protein family UPF0758, YicR subfamily WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 TIGRFAM TIGR00608 radc: DNA repair protein RadC 9 221 4.0E-87 T 28-03-2018 IPR001405 RadC protein WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 Gene3D G3DSA:1.10.150.20 42 82 1.9E-4 T 28-03-2018 WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 SUPERFAMILY SSF47781 14 84 1.65E-9 T 28-03-2018 IPR010994 RuvA domain 2-like WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 Pfam PF04002 RadC-like JAB domain 106 219 6.9E-43 T 28-03-2018 IPR025657 RadC-like JAB domain WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 170 175 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site WM46_RS20140 ab50e43fb4c4104a7d41f1946b79ab11 221 Gene3D G3DSA:3.40.140.10 97 221 8.3E-46 T 28-03-2018 WM46_RS14500 6e184ace4930e6c264568a227b85d55f 232 TIGRFAM TIGR01277 thiQ: thiamine ABC transporter, ATP-binding protein 2 214 3.7E-111 T 28-03-2018 IPR005968 Thiamine ABC transporter, ATP-binding protein ThiQ GO:0005524|GO:0006810|GO:0016021|GO:0042626 WM46_RS14500 6e184ace4930e6c264568a227b85d55f 232 SMART SM00382 24 209 9.3E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain WM46_RS14500 6e184ace4930e6c264568a227b85d55f 232 SUPERFAMILY SSF52540 1 222 1.86E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS14500 6e184ace4930e6c264568a227b85d55f 232 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 WM46_RS14500 6e184ace4930e6c264568a227b85d55f 232 Gene3D G3DSA:3.40.50.300 4 229 5.1E-59 T 28-03-2018 WM46_RS14500 6e184ace4930e6c264568a227b85d55f 232 Pfam PF00005 ABC transporter 18 157 6.0E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 WM46_RS19945 f81c0c4a101721688c32c1b77a9f882b 249 Pfam PF03609 PTS system sorbose-specific iic component 7 238 3.0E-74 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS22445 eb3c62bc3ccff12211ec9153d4107bef 358 Gene3D G3DSA:2.60.40.1090 184 358 2.2E-10 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS04665 cb9543de7a8dc8f8bb6a9fe99de89a1e 467 Pfam PF13264 Domain of unknown function (DUF4055) 248 387 1.5E-40 T 28-03-2018 IPR025129 Domain of unknown function DUF4055 WM46_RS00095 6b550686e8a7d20293895561ce77e33a 409 SUPERFAMILY SSF47413 65 126 1.73E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 WM46_RS00095 6b550686e8a7d20293895561ce77e33a 409 Gene3D G3DSA:1.10.260.40 47 340 5.0E-7 T 28-03-2018 WM46_RS00095 6b550686e8a7d20293895561ce77e33a 409 Pfam PF06114 IrrE N-terminal-like domain 266 351 1.6E-8 T 28-03-2018 IPR010359 IrrE N-terminal-like domain WM46_RS06275 c8c76c057c608ab0ce3bc0995137071b 175 SUPERFAMILY SSF54001 56 173 1.41E-38 T 28-03-2018 WM46_RS06275 c8c76c057c608ab0ce3bc0995137071b 175 Pfam PF00877 NlpC/P60 family 68 172 1.2E-31 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain WM46_RS06275 c8c76c057c608ab0ce3bc0995137071b 175 Gene3D G3DSA:3.90.1720.10 51 175 5.4E-35 T 28-03-2018 WM46_RS00010 1fa3d33f41dac82741f4b56253282df7 668 Gene3D G3DSA:1.10.443.10 195 501 3.0E-21 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS00580 866994982ecf651ee5705c1bf7db1a3b 209 Pfam PF06226 Protein of unknown function (DUF1007) 6 208 3.7E-64 T 28-03-2018 IPR010412 Protein of unknown function DUF1007 WM46_RS00580 866994982ecf651ee5705c1bf7db1a3b 209 PIRSF PIRSF008159 1 209 5.4E-69 T 28-03-2018 IPR016537 Uncharacterised conserved protein UCP008159, WM46_RS11080 8497d6359a26873e5cfab718c4139b7f 317 PIRSF PIRSF037004 1 317 1.5E-129 T 28-03-2018 IPR017087 Uncharacterised conserved protein UCP037004 WM46_RS11080 8497d6359a26873e5cfab718c4139b7f 317 Pfam PF08349 Protein of unknown function (DUF1722) 191 308 3.0E-41 T 28-03-2018 IPR013560 Domain of unknown function DUF1722 WM46_RS11080 8497d6359a26873e5cfab718c4139b7f 317 Pfam PF04463 Protein of unknown function (DUF523) 7 148 2.4E-37 T 28-03-2018 IPR007553 Domain of unknown function DUF523 WM46_RS19110 338d63b3e55712cfc4caa989583c13eb 235 Gene3D G3DSA:3.30.450.40 49 224 1.1E-5 T 28-03-2018 IPR029016 GAF domain-like WM46_RS19110 338d63b3e55712cfc4caa989583c13eb 235 Pfam PF04340 Protein of unknown function, DUF484 11 232 1.2E-83 T 28-03-2018 IPR007435 Protein of unknown function DUF484 WM46_RS19785 a028efad0f6c6a9ad06ae278938bf570 277 SUPERFAMILY SSF103481 175 276 1.44E-12 T 28-03-2018 WM46_RS19785 a028efad0f6c6a9ad06ae278938bf570 277 SUPERFAMILY SSF103481 39 136 9.68E-12 T 28-03-2018 WM46_RS19785 a028efad0f6c6a9ad06ae278938bf570 277 Pfam PF00892 EamA-like transporter family 141 274 9.6E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS23725 e799587697d016c94ebb98344295373b 398 Pfam PF02515 CoA-transferase family III 8 374 1.7E-131 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 WM46_RS23725 e799587697d016c94ebb98344295373b 398 SUPERFAMILY SSF89796 6 397 1.96E-136 T 28-03-2018 IPR023606 CoA-transferase family III domain WM46_RS23725 e799587697d016c94ebb98344295373b 398 Gene3D G3DSA:3.40.50.10540 2 398 3.5E-146 T 28-03-2018 IPR023606 CoA-transferase family III domain WM46_RS06105 535f324c9d283a8109a6464430500fa5 353 Pfam PF05128 Domain of unknown function (DUF697) 183 341 2.7E-54 T 28-03-2018 IPR021147 Protein of unknown function DUF697 WM46_RS06105 535f324c9d283a8109a6464430500fa5 353 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 54 341 5.9E-149 T 28-03-2018 IPR006507 Uncharacterised protein family UPF0283 WM46_RS06105 535f324c9d283a8109a6464430500fa5 353 Hamap MF_01085 UPF0283 membrane protein YcjF [ycjF]. 4 347 39.272 T 28-03-2018 IPR006507 Uncharacterised protein family UPF0283 WM46_RS02025 0ddc746af3c3ca8548ce0a43c49d7b93 338 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 4 190 1.6E-50 T 28-03-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS02025 0ddc746af3c3ca8548ce0a43c49d7b93 338 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 245 337 4.3E-38 T 28-03-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 WM46_RS06280 a54b8cfa106d3b9b46147f26bca3c0e7 90 Pfam PF03891 Domain of unknown function (DUF333) 40 85 1.6E-15 T 28-03-2018 IPR005590 Protein of unknown function DUF333 WM46_RS24440 d61d464521f545fbe61e258b25123c60 278 Pfam PF00149 Calcineurin-like phosphoesterase 3 198 2.4E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 WM46_RS24440 d61d464521f545fbe61e258b25123c60 278 SUPERFAMILY SSF56300 1 256 1.52E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS24440 d61d464521f545fbe61e258b25123c60 278 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 254 36.792 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 WM46_RS24440 d61d464521f545fbe61e258b25123c60 278 Gene3D G3DSA:3.60.21.10 1 263 6.5E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like WM46_RS05015 99739f13ead4270cdd0f57ae90c74bcd 193 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 7 189 3.8E-82 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 WM46_RS05015 99739f13ead4270cdd0f57ae90c74bcd 193 PIRSF PIRSF004982 5 189 2.2E-54 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 WM46_RS05015 99739f13ead4270cdd0f57ae90c74bcd 193 Pfam PF03843 Outer membrane lipoprotein Slp family 20 167 6.5E-48 T 28-03-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 WM46_RS16075 d1a6286fa924bd791b16f3ced5e20141 104 Gene3D G3DSA:3.30.70.100 1 102 4.2E-21 T 28-03-2018 WM46_RS16075 d1a6286fa924bd791b16f3ced5e20141 104 SUPERFAMILY SSF54909 1 99 1.11E-30 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel WM46_RS16075 d1a6286fa924bd791b16f3ced5e20141 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 87 1.0E-28 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain WM46_RS15065 1dca9b156086d4f7c2fa3ae06d5e244a 187 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 1 187 39.51 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 WM46_RS15065 1dca9b156086d4f7c2fa3ae06d5e244a 187 Gene3D G3DSA:3.40.1740.10 101 179 1.3E-11 T 28-03-2018 WM46_RS15065 1dca9b156086d4f7c2fa3ae06d5e244a 187 Gene3D G3DSA:3.40.1740.10 1 95 6.7E-29 T 28-03-2018 WM46_RS15065 1dca9b156086d4f7c2fa3ae06d5e244a 187 SUPERFAMILY SSF143456 1 187 5.1E-65 T 28-03-2018 WM46_RS15065 1dca9b156086d4f7c2fa3ae06d5e244a 187 Pfam PF02622 Uncharacterized ACR, COG1678 12 174 5.5E-48 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 WM46_RS08950 d31c6ea13a3c321e49addfe356bd9f7d 151 Pfam PF07012 Curlin associated repeat 100 130 3.2E-8 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS08950 d31c6ea13a3c321e49addfe356bd9f7d 151 Pfam PF07012 Curlin associated repeat 53 86 2.7E-7 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS08950 d31c6ea13a3c321e49addfe356bd9f7d 151 Pfam PF07012 Curlin associated repeat 77 106 2.7E-9 T 28-03-2018 IPR009742 Curlin associated GO:0007155|GO:0009289 WM46_RS25805 8345e660c71e8f84d3a588de8cb2cc00 952 Gene3D G3DSA:3.40.50.300 100 353 2.8E-4 T 28-03-2018 WM46_RS25805 8345e660c71e8f84d3a588de8cb2cc00 952 Pfam PF10593 Z1 domain 437 670 5.1E-83 T 28-03-2018 IPR018310 Putative endonuclease, Z1 domain WM46_RS21275 eaef37887ae89f3b355509a7c49d133c 231 Pfam PF08139 Prokaryotic membrane lipoprotein lipid attachment site 6 33 2.5E-5 T 28-03-2018 IPR012640 Membrane lipoprotein, lipid attachment site WM46_RS21275 eaef37887ae89f3b355509a7c49d133c 231 PIRSF PIRSF006993 1 231 1.1E-110 T 28-03-2018 IPR016500 Uncharacterised conserved protein UCP006993 WM46_RS21275 eaef37887ae89f3b355509a7c49d133c 231 Pfam PF07356 Protein of unknown function (DUF1481) 42 227 2.0E-69 T 28-03-2018 IPR010858 Protein of unknown function DUF1481 WM46_RS02875 e79e1da2a60da0a32f52c98ec8e7e961 492 Pfam PF13440 Polysaccharide biosynthesis protein 31 325 1.4E-67 T 28-03-2018 WM46_RS03605 439a822b5d3eea9536469b949b341fc6 245 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 31 244 27.419 T 28-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 WM46_RS03605 439a822b5d3eea9536469b949b341fc6 245 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 31 241 5.2E-112 T 28-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 WM46_RS03605 439a822b5d3eea9536469b949b341fc6 245 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 32 237 1.5E-52 T 28-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 WM46_RS14955 0b7a013968911a718a8e8cc8e7ad208c 235 Pfam PF02361 Cobalt transport protein 10 201 3.0E-7 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component WM46_RS22410 7481d0dab2ab2d0656e53bf106c50110 136 SUPERFAMILY SSF103481 34 123 1.44E-5 T 28-03-2018 WM46_RS22410 7481d0dab2ab2d0656e53bf106c50110 136 Hamap MF_00538 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF [arnF]. 2 124 18.471 T 28-03-2018 IPR022832 Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF WM46_RS08410 164b194ac96f1db0988c0f2c1a3b47d3 115 Pfam PF04343 Protein of unknown function, DUF488 5 112 3.5E-32 T 28-03-2018 IPR007438 Protein of unknown function DUF488 WM46_RS23160 12dffed0608d2e3fe10c74f81f3e99ee 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 304 6.2E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS23160 12dffed0608d2e3fe10c74f81f3e99ee 333 Gene3D G3DSA:1.10.3470.10 31 310 2.8E-29 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS19730 2ef6f8571d229f2d4b2e649a84dd1bbc 487 SUPERFAMILY SSF53649 4 385 2.75E-70 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS19730 2ef6f8571d229f2d4b2e649a84dd1bbc 487 SUPERFAMILY SSF53649 436 474 2.75E-70 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS19730 2ef6f8571d229f2d4b2e649a84dd1bbc 487 Gene3D G3DSA:3.40.720.10 3 354 3.5E-57 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS19730 2ef6f8571d229f2d4b2e649a84dd1bbc 487 Pfam PF00884 Sulfatase 4 333 6.3E-34 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS08970 7d2a048d677c3ff2a74b8fe284c745bd 277 Pfam PF03783 Curli production assembly/transport component CsgG 41 255 4.1E-80 T 28-03-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 WM46_RS08970 7d2a048d677c3ff2a74b8fe284c745bd 277 Gene3D G3DSA:3.40.50.10070 44 210 9.4E-18 T 28-03-2018 WM46_RS15695 094c3d0f3d5ea0a49b86861564b7ebb7 291 Gene3D G3DSA:3.40.50.300 1 283 8.7E-30 T 28-03-2018 WM46_RS15695 094c3d0f3d5ea0a49b86861564b7ebb7 291 Pfam PF13614 AAA domain 1 143 3.4E-16 T 28-03-2018 IPR025669 AAA domain WM46_RS15695 094c3d0f3d5ea0a49b86861564b7ebb7 291 SUPERFAMILY SSF52540 1 274 1.23E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS03415 3c3617819fc3d8d99385f21845607d38 352 Pfam PF04632 Fusaric acid resistance protein family 21 339 1.3E-18 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 WM46_RS18455 c07a46bcf7e51398d2b01e524c0c21a3 198 Pfam PF07305 Protein of unknown function (DUF1454) 20 192 2.3E-83 T 28-03-2018 IPR009918 Protein of unknown function DUF1454 WM46_RS10140 2c2f369684870aa6f06768302ab2a7da 162 Pfam PF10767 Protein of unknown function (DUF2593) 21 160 4.1E-61 T 28-03-2018 IPR019703 Protein of unknown function DUF2593 WM46_RS09790 55c4e07cf54682e7cb9bde9c75b73fd2 234 Hamap MF_01802 Chromosome partition protein MukE [mukE]. 10 234 48.414 T 28-03-2018 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 WM46_RS09790 55c4e07cf54682e7cb9bde9c75b73fd2 234 Pfam PF04288 MukE-like family 10 230 1.2E-125 T 28-03-2018 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 WM46_RS23620 de428cbbe10ee47f15f7845e3e830dd8 272 Pfam PF06067 Domain of unknown function (DUF932) 36 261 6.5E-54 T 28-03-2018 IPR026325 Protein of unknown function DUF932 WM46_RS24065 6654c6c115469e1c9d1cab761ad223f5 205 Pfam PF04972 BON domain 59 126 8.6E-20 T 28-03-2018 IPR007055 BON domain WM46_RS24065 6654c6c115469e1c9d1cab761ad223f5 205 Pfam PF04972 BON domain 139 203 1.2E-19 T 28-03-2018 IPR007055 BON domain WM46_RS24065 6654c6c115469e1c9d1cab761ad223f5 205 SMART SM00749 64 127 9.9E-12 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM46_RS24065 6654c6c115469e1c9d1cab761ad223f5 205 SMART SM00749 143 205 4.8E-10 T 28-03-2018 IPR014004 Transport-associated and nodulation domain, bacteria WM46_RS23890 8da51e51eaa72210e14d579c5c8a4533 354 Pfam PF11168 Protein of unknown function (DUF2955) 25 163 1.9E-41 T 28-03-2018 IPR022604 Protein of unknown function DUF2955 WM46_RS23890 8da51e51eaa72210e14d579c5c8a4533 354 PIRSF PIRSF029594 18 353 2.2E-103 T 28-03-2018 IPR016926 Uncharacterised conserved protein UCP029594 WM46_RS06850 ca1688200ec0a926384f8a5cf8796589 340 SUPERFAMILY SSF161098 199 319 8.37E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06850 ca1688200ec0a926384f8a5cf8796589 340 SUPERFAMILY SSF161098 96 161 8.37E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS06850 ca1688200ec0a926384f8a5cf8796589 340 Gene3D G3DSA:1.10.3720.10 3 324 9.6E-41 T 28-03-2018 WM46_RS06850 ca1688200ec0a926384f8a5cf8796589 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 8.4E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS23295 f904fddd042af58372396d6312f369c5 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 155 3.4E-23 T 28-03-2018 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component WM46_RS20880 ac8157a8d5f9ae6d16b8da5919e24344 202 SUPERFAMILY SSF54001 19 195 3.92E-48 T 28-03-2018 WM46_RS20880 ac8157a8d5f9ae6d16b8da5919e24344 202 Gene3D G3DSA:3.90.1720.10 17 202 8.1E-44 T 28-03-2018 WM46_RS20880 ac8157a8d5f9ae6d16b8da5919e24344 202 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 22 193 8.5E-46 T 28-03-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family WM46_RS25755 9fd4a762199fc9c31bb0955fbefe7643 143 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 6 137 2.1E-18 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 WM46_RS23640 feea372a28690576870354775258230d 117 Pfam PF06154 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A 14 112 4.9E-53 T 28-03-2018 IPR009320 Antitoxin CbeA GO:0051495 WM46_RS23640 feea372a28690576870354775258230d 117 SUPERFAMILY SSF143737 6 114 3.79E-54 T 28-03-2018 WM46_RS23640 feea372a28690576870354775258230d 117 Gene3D G3DSA:3.30.450.20 22 114 6.9E-52 T 28-03-2018 WM46_RS15970 a0c00895bfc87d9e3243ea4e8d1005d8 346 Gene3D G3DSA:3.20.20.100 15 334 1.5E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS15970 a0c00895bfc87d9e3243ea4e8d1005d8 346 Pfam PF00248 Aldo/keto reductase family 28 332 2.2E-79 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS15970 a0c00895bfc87d9e3243ea4e8d1005d8 346 SUPERFAMILY SSF51430 13 331 8.9E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain WM46_RS00585 ae0b8afb65e19f9d05fbf5ec6ca887de 326 Pfam PF03824 High-affinity nickel-transport protein 73 179 1.5E-21 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 WM46_RS00585 ae0b8afb65e19f9d05fbf5ec6ca887de 326 Pfam PF03824 High-affinity nickel-transport protein 187 316 1.6E-20 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 WM46_RS09070 ce4a1323ebd9de6a114fb7a28f5c0b94 450 Pfam PF06812 ImpA, N-terminal, type VI secretion system 12 113 4.5E-21 T 28-03-2018 IPR010657 ImpA, N-terminal WM46_RS09070 ce4a1323ebd9de6a114fb7a28f5c0b94 450 Pfam PF12486 Type VI secretion system, EvfB, or VasL 292 437 2.3E-27 T 28-03-2018 IPR021069 ImpA, C-terminal WM46_RS12780 b66a43194500bfa0c49a53da8853be37 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 7.1E-78 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 WM46_RS12780 b66a43194500bfa0c49a53da8853be37 149 Pfam PF03477 ATP cone domain 50 136 1.0E-15 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 WM46_RS12780 b66a43194500bfa0c49a53da8853be37 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 89.187 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 WM46_RS21035 df398a70ed70aa9ed01697d147c26671 348 Gene3D G3DSA:1.10.3470.10 7 322 5.6E-16 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS21035 df398a70ed70aa9ed01697d147c26671 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 316 6.4E-25 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS09700 38650a16fdacd062a2d37294dfecf97e 180 Hamap MF_00906 Cell division protein ZapC [zapC]. 2 178 39.596 T 28-03-2018 IPR009809 Cell division protein ZapC WM46_RS09700 38650a16fdacd062a2d37294dfecf97e 180 PIRSF PIRSF010252 1 179 9.2E-64 T 28-03-2018 IPR009809 Cell division protein ZapC WM46_RS09700 38650a16fdacd062a2d37294dfecf97e 180 Pfam PF07126 Cell-division protein ZapC 3 167 8.3E-67 T 28-03-2018 IPR009809 Cell division protein ZapC WM46_RS16455 5ec65723d0a1deca2c503f0d572141b0 118 Pfam PF05656 Protein of unknown function (DUF805) 11 117 3.6E-35 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 WM46_RS06155 bf09e8c676c7956144af093f8dfc4661 316 SUPERFAMILY SSF52402 155 307 2.34E-24 T 28-03-2018 WM46_RS06155 bf09e8c676c7956144af093f8dfc4661 316 Gene3D G3DSA:3.40.50.620 1 153 6.9E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS06155 bf09e8c676c7956144af093f8dfc4661 316 Gene3D G3DSA:3.40.50.620 154 304 4.5E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold WM46_RS06155 bf09e8c676c7956144af093f8dfc4661 316 SUPERFAMILY SSF52402 4 153 5.78E-26 T 28-03-2018 WM46_RS06155 bf09e8c676c7956144af093f8dfc4661 316 Pfam PF00582 Universal stress protein family 3 146 1.0E-17 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS06155 bf09e8c676c7956144af093f8dfc4661 316 Pfam PF00582 Universal stress protein family 174 300 2.2E-14 T 28-03-2018 IPR006016 UspA GO:0006950 WM46_RS03890 2cc8a35455f00a5ba755d32c18385a0f 183 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 90 165 1.6E-13 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 WM46_RS03890 2cc8a35455f00a5ba755d32c18385a0f 183 TIGRFAM TIGR03823 FliZ: flagellar regulatory protein FliZ 1 165 1.5E-87 T 28-03-2018 IPR022523 Flagellar regulator, FliZ WM46_RS02890 ad1c58f4bfcb258efbb02e52a6c8eb78 472 SUPERFAMILY SSF51126 47 351 6.94E-20 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor WM46_RS02890 ad1c58f4bfcb258efbb02e52a6c8eb78 472 Gene3D G3DSA:2.160.20.10 284 392 4.7E-5 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS02890 ad1c58f4bfcb258efbb02e52a6c8eb78 472 TIGRFAM TIGR04004 WcaM: colanic acid biosynthesis protein WcaM 3 464 1.8E-296 T 28-03-2018 IPR023882 Colanic acid biosynthesis WcaM WM46_RS02890 ad1c58f4bfcb258efbb02e52a6c8eb78 472 Gene3D G3DSA:2.160.20.10 25 283 4.9E-14 T 28-03-2018 IPR012334 Pectin lyase fold WM46_RS11330 d493ee9dbbbcfca35e4ac2f77e3353d4 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 223 1.7E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS11330 d493ee9dbbbcfca35e4ac2f77e3353d4 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 118 6.1E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS11330 d493ee9dbbbcfca35e4ac2f77e3353d4 224 SUPERFAMILY SSF161098 14 210 6.54E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS11330 d493ee9dbbbcfca35e4ac2f77e3353d4 224 Gene3D G3DSA:1.10.3720.10 2 224 7.2E-41 T 28-03-2018 WM46_RS09100 0b8cf64d8013499a9f4b6485f3cdb78b 302 Pfam PF02562 PhoH-like protein 97 301 8.9E-77 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 WM46_RS09100 0b8cf64d8013499a9f4b6485f3cdb78b 302 Gene3D G3DSA:3.40.50.300 94 301 9.4E-21 T 28-03-2018 WM46_RS09100 0b8cf64d8013499a9f4b6485f3cdb78b 302 SUPERFAMILY SSF52540 96 279 1.61E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS06595 79146f168760d5fbebff582138b80f46 716 Gene3D G3DSA:1.20.140.50 5 614 4.9E-4 T 28-03-2018 WM46_RS06595 79146f168760d5fbebff582138b80f46 716 Pfam PF10139 Putative bacterial virulence factor 546 712 8.3E-25 T 28-03-2018 IPR017030 Virulence effector, SrfC WM46_RS06595 79146f168760d5fbebff582138b80f46 716 Pfam PF10139 Putative bacterial virulence factor 11 416 2.8E-63 T 28-03-2018 IPR017030 Virulence effector, SrfC WM46_RS06595 79146f168760d5fbebff582138b80f46 716 PIRSF PIRSF034586 1 414 1.0E-132 T 28-03-2018 IPR017030 Virulence effector, SrfC WM46_RS06595 79146f168760d5fbebff582138b80f46 716 PIRSF PIRSF034586 410 716 1.6E-75 T 28-03-2018 IPR017030 Virulence effector, SrfC WM46_RS16610 8c2668ad544ec4f7ba63a8664e906ba0 144 SUPERFAMILY SSF53062 1 126 6.28E-33 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS16610 8c2668ad544ec4f7ba63a8664e906ba0 144 Gene3D G3DSA:3.40.50.510 1 143 9.2E-31 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS16610 8c2668ad544ec4f7ba63a8664e906ba0 144 Pfam PF03610 PTS system fructose IIA component 3 113 1.5E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 WM46_RS01575 d6209981549b9d0b16349497879b2eed 219 Pfam PF09335 SNARE associated Golgi protein 49 176 7.9E-27 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS06005 61145d4fdc634cca8a7b9446df252526 189 SUPERFAMILY SSF49401 24 189 2.68E-22 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06005 61145d4fdc634cca8a7b9446df252526 189 Gene3D G3DSA:2.60.40.1090 23 189 4.7E-27 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS16085 160b4971b2d169dc2d3939a222bd5e0e 396 SUPERFAMILY SSF48208 27 396 1.87E-116 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 WM46_RS16085 160b4971b2d169dc2d3939a222bd5e0e 396 Pfam PF07470 Glycosyl Hydrolase Family 88 62 388 7.6E-32 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 WM46_RS16085 160b4971b2d169dc2d3939a222bd5e0e 396 Gene3D G3DSA:1.50.10.10 26 396 5.9E-93 T 28-03-2018 WM46_RS16165 eb989ce655d78bbd4731a94b221dbf68 598 Pfam PF05935 Arylsulfotransferase (ASST) 146 587 9.8E-139 T 28-03-2018 IPR010262 Arylsulfotransferase, C-terminal WM46_RS16165 eb989ce655d78bbd4731a94b221dbf68 598 Hamap MF_00933 Arylsulfate sulfotransferase AssT [assT]. 1 598 89.289 T 28-03-2018 IPR028610 Arylsulfate sulfotransferase AssT, Enterobacteria GO:0004062 WM46_RS16165 eb989ce655d78bbd4731a94b221dbf68 598 Pfam PF17425 Arylsulfotransferase Ig-like domain 42 127 1.6E-25 T 28-03-2018 IPR035391 Arylsulfotransferase, Ig-like domain WM46_RS00475 ba0e8317e2003ac404474e267ab674bd 415 Pfam PF03811 InsA N-terminal domain 75 103 4.2E-9 T 28-03-2018 IPR003220 InsA N-terminal domain GO:0006313 WM46_RS06140 9506f2eb3567aca42fb0a68f4387b9fa 127 Gene3D G3DSA:3.10.180.10 1 127 1.0E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS06140 9506f2eb3567aca42fb0a68f4387b9fa 127 SUPERFAMILY SSF54593 1 127 3.36E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS06140 9506f2eb3567aca42fb0a68f4387b9fa 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 125 4.8E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain WM46_RS01595 92cf492ea101d7a38c7a8efbace230ae 162 Pfam PF02674 Colicin V production protein 4 141 3.9E-36 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 WM46_RS09170 dbb87676d25cc6e9f3f6d511a099c54a 252 Pfam PF01925 Sulfite exporter TauE/SafE 16 246 6.6E-27 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 WM46_RS07760 55113368b2646aa3023e80bb92c6a5ea 69 Pfam PF10965 Protein of unknown function (DUF2767) 1 67 1.6E-33 T 28-03-2018 IPR024493 Fumarase D WM46_RS07760 55113368b2646aa3023e80bb92c6a5ea 69 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 67 2.0E-30 T 28-03-2018 WM46_RS08505 090660ed1755fb92b2322cf7c09200a4 373 Pfam PF08007 Cupin superfamily protein 10 310 2.0E-104 T 28-03-2018 IPR003347 JmjC domain WM46_RS08505 090660ed1755fb92b2322cf7c09200a4 373 SMART SM00558 92 215 2.2E-11 T 28-03-2018 IPR003347 JmjC domain WM46_RS08505 090660ed1755fb92b2322cf7c09200a4 373 Gene3D G3DSA:2.60.120.650 2 209 9.6E-29 T 28-03-2018 WM46_RS08505 090660ed1755fb92b2322cf7c09200a4 373 SUPERFAMILY SSF51197 7 292 3.3E-75 T 28-03-2018 WM46_RS15820 4fc29d64d23a365194f3e11c40108aa1 191 Pfam PF11726 Inovirus Gp2 24 170 4.5E-9 T 28-03-2018 WM46_RS15115 0ca3db81388ed42119720b85b389a428 239 Pfam PF11101 Protein of unknown function (DUF2884) 24 237 3.5E-40 T 28-03-2018 IPR021307 Protein of unknown function DUF2884 WM46_RS24980 93391295adf140b3b694a932ebcac386 131 Pfam PF04241 Protein of unknown function (DUF423) 20 106 2.0E-23 T 28-03-2018 IPR006696 Protein of unknown function DUF423 WM46_RS15875 684400133235dc5ff2f9391053a50412 119 Pfam PF06154 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A 16 114 2.6E-52 T 28-03-2018 IPR009320 Antitoxin CbeA GO:0051495 WM46_RS15875 684400133235dc5ff2f9391053a50412 119 Gene3D G3DSA:3.30.450.20 24 116 1.9E-51 T 28-03-2018 WM46_RS15875 684400133235dc5ff2f9391053a50412 119 SUPERFAMILY SSF143737 4 115 4.32E-55 T 28-03-2018 WM46_RS12850 97492f7311bd1d01e8c38bbed6434aa3 463 Pfam PF03611 PTS system sugar-specific permease component 10 404 5.0E-126 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 WM46_RS18280 ba77efc404acee3ddab7131871a14b86 563 SUPERFAMILY SSF53448 8 242 1.29E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18280 ba77efc404acee3ddab7131871a14b86 563 Pfam PF00535 Glycosyl transferase family 2 8 127 3.2E-18 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 WM46_RS18280 ba77efc404acee3ddab7131871a14b86 563 Gene3D G3DSA:3.90.550.10 8 256 3.0E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS23400 010858af40cc0b3b24c1c2daf611989e 399 Pfam PF05987 Bacterial protein of unknown function (DUF898) 14 380 1.2E-59 T 28-03-2018 IPR010295 Protein of unknown function DUF898 WM46_RS22250 6593243c2e2e829afec44289c20d2d65 359 Pfam PF00482 Type II secretion system (T2SS), protein F 39 152 4.2E-7 T 28-03-2018 IPR018076 Type II secretion system F domain WM46_RS22250 6593243c2e2e829afec44289c20d2d65 359 Pfam PF00482 Type II secretion system (T2SS), protein F 227 343 2.8E-13 T 28-03-2018 IPR018076 Type II secretion system F domain WM46_RS23965 871f9c127e121db5506ecb2ff8a4ea10 181 Hamap MF_01061 Primosomal protein 1 [dnaT]. 3 180 42.99 T 28-03-2018 IPR020917 Primosomal protein 1 GO:0006260 WM46_RS14450 029284f57ff1cae892c58caebd39087f 28 Pfam PF08054 Leucine operon leader peptide 1 28 4.6E-14 T 28-03-2018 IPR012570 Leucine operon leader peptide GO:0009098 WM46_RS18800 6913fee374f8ceddc0441ab132be5c28 291 Pfam PF01925 Sulfite exporter TauE/SafE 23 249 2.4E-31 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 WM46_RS08310 96f3d090e231910f9a07fbc957b40689 213 SUPERFAMILY SSF52499 3 208 1.96E-53 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS08310 96f3d090e231910f9a07fbc957b40689 213 Gene3D G3DSA:3.40.50.850 1 213 1.1E-62 T 28-03-2018 WM46_RS08310 96f3d090e231910f9a07fbc957b40689 213 Pfam PF00857 Isochorismatase family 5 207 4.7E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 WM46_RS02540 ab9aa75e2e02bd5ccec4847752ba876e 191 Pfam PF09335 SNARE associated Golgi protein 23 143 3.1E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS16600 882b9d464adf2a38c9af882c621c8f5f 259 Pfam PF03609 PTS system sorbose-specific iic component 5 236 8.0E-70 T 28-03-2018 IPR004700 Phosphotransferase system, mannose/fructose/sorbose family, IIC subunit GO:0009401|GO:0016021 WM46_RS16255 2636cdfb40103a0f831129420adbb491 487 PIRSF PIRSF002457 2 487 3.6E-133 T 28-03-2018 IPR030676 Citrate carrier CitT-related WM46_RS16255 2636cdfb40103a0f831129420adbb491 487 Pfam PF00939 Sodium:sulfate symporter transmembrane region 6 486 7.4E-182 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS16255 2636cdfb40103a0f831129420adbb491 487 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 24 482 2.1E-166 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 WM46_RS12000 aee311ece092db521465d50a8ed511ab 170 SUPERFAMILY SSF49401 25 170 3.58E-25 T 28-03-2018 IPR008966 Adhesion domain WM46_RS12000 aee311ece092db521465d50a8ed511ab 170 Gene3D G3DSA:2.60.40.1090 24 170 1.4E-25 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS20515 75882ee33f1f290e650f926199fbf4cc 236 Pfam PF11254 Protein of unknown function (DUF3053) 15 230 1.2E-91 T 28-03-2018 IPR021413 Protein of unknown function DUF3053 WM46_RS22290 846db8960eafd36865773f54e030154e 207 Gene3D G3DSA:1.10.530.10 22 187 4.0E-13 T 28-03-2018 WM46_RS22290 846db8960eafd36865773f54e030154e 207 SUPERFAMILY SSF53955 35 78 1.97E-15 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS22290 846db8960eafd36865773f54e030154e 207 SUPERFAMILY SSF53955 106 181 1.97E-15 T 28-03-2018 IPR023346 Lysozyme-like domain WM46_RS17365 e2c4ef69e5ea1fe6af2674a8c205e3cc 157 Hamap MF_00598 Protein Smg [smg]. 1 157 33.6 T 28-03-2018 IPR007456 Smg WM46_RS17365 e2c4ef69e5ea1fe6af2674a8c205e3cc 157 Pfam PF04361 Protein of unknown function (DUF494) 1 157 2.3E-59 T 28-03-2018 IPR007456 Smg WM46_RS24630 6ad96251c761e3ac9d66a13e0f4a21cb 201 Gene3D G3DSA:1.10.443.10 11 183 1.5E-39 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS24630 6ad96251c761e3ac9d66a13e0f4a21cb 201 Pfam PF00589 Phage integrase family 12 180 6.9E-50 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 WM46_RS24630 6ad96251c761e3ac9d66a13e0f4a21cb 201 SUPERFAMILY SSF56349 7 189 2.21E-43 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 WM46_RS26005 fc025ebd1091e6d9ed2c51746443eca2 346 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 40 262 1.2E-40 T 28-03-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 WM46_RS22235 0ae16a900c226e5d27c9ecae0dbf1070 433 Pfam PF06864 Pilin accessory protein (PilO) 28 431 1.6E-68 T 28-03-2018 IPR009663 Pilin accessory predicted WM46_RS04730 ce43d7bb56261ab235b6d5448c9aad02 116 Pfam PF08748 Phage tail assembly chaperone 1 116 2.8E-26 T 28-03-2018 IPR014859 Phage tail assembly chaperone WM46_RS18100 04040b736dc76c22864446d212cd6809 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 293 2.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS18100 04040b736dc76c22864446d212cd6809 295 SUPERFAMILY SSF161098 56 282 8.37E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS18100 04040b736dc76c22864446d212cd6809 295 Gene3D G3DSA:1.10.3720.10 13 295 2.9E-44 T 28-03-2018 WM46_RS21625 9384a6e561861b85b8fb7b144f6e0a82 80 Pfam PF09583 Phage shock protein G (Phageshock_PspG) 1 63 9.2E-26 T 28-03-2018 IPR014318 Phage shock protein, PspG WM46_RS21625 9384a6e561861b85b8fb7b144f6e0a82 80 TIGRFAM TIGR02975 phageshock_pspG: phage shock protein G 2 64 3.4E-27 T 28-03-2018 IPR014318 Phage shock protein, PspG WM46_RS16395 8fee489589f0b3b73942c6ba1c510c52 495 SMART SM00858 10 81 7.5E-20 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 WM46_RS16395 8fee489589f0b3b73942c6ba1c510c52 495 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 108 494 1.9E-154 T 28-03-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 WM46_RS16395 8fee489589f0b3b73942c6ba1c510c52 495 Pfam PF08666 SAF domain 10 81 9.5E-17 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 WM46_RS23630 c759f1af5a559d924cad5ad28c1a330b 159 TIGRFAM TIGR00608 radc: DNA repair protein RadC 38 159 3.9E-42 T 28-03-2018 IPR001405 RadC protein WM46_RS23630 c759f1af5a559d924cad5ad28c1a330b 159 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 108 113 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site WM46_RS23630 c759f1af5a559d924cad5ad28c1a330b 159 Pfam PF04002 RadC-like JAB domain 38 157 4.0E-41 T 28-03-2018 IPR025657 RadC-like JAB domain WM46_RS23630 c759f1af5a559d924cad5ad28c1a330b 159 Gene3D G3DSA:3.40.140.10 35 159 1.4E-43 T 28-03-2018 WM46_RS20640 a3c86efdb37aba4608172f2fe7fa0e1a 63 TIGRFAM TIGR03493 cellullose_BcsF: celllulose biosynthesis operon protein BcsF/YhjT 2 63 1.7E-32 T 28-03-2018 IPR019995 Cellulose biosynthesis, BcsF/YhjT WM46_RS20640 a3c86efdb37aba4608172f2fe7fa0e1a 63 Pfam PF11120 Cellulose biosynthesis protein BcsF 2 59 1.2E-28 T 28-03-2018 IPR019995 Cellulose biosynthesis, BcsF/YhjT WM46_RS20640 a3c86efdb37aba4608172f2fe7fa0e1a 63 ProDom PD053231 YHJT MEMBRANE INNER BCSF 2 63 2.0E-23 T 28-03-2018 IPR019995 Cellulose biosynthesis, BcsF/YhjT WM46_RS21600 919e5ce44b3b314c87968a1bd0c4f8c3 441 Pfam PF01554 MatE 241 394 8.2E-11 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS21600 919e5ce44b3b314c87968a1bd0c4f8c3 441 Pfam PF01554 MatE 17 177 1.4E-33 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS21600 919e5ce44b3b314c87968a1bd0c4f8c3 441 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 410 4.8E-100 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 WM46_RS13360 ba30981c3cfb494fb3294a989a7a26ff 267 Gene3D G3DSA:3.90.850.10 1 267 5.2E-46 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13360 ba30981c3cfb494fb3294a989a7a26ff 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 265 2.1E-6 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS13360 ba30981c3cfb494fb3294a989a7a26ff 267 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 267 7.7E-140 T 28-03-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 WM46_RS13360 ba30981c3cfb494fb3294a989a7a26ff 267 SUPERFAMILY SSF56529 2 267 5.63E-77 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 WM46_RS00660 c0ad80203c01334adc80c80ecea44cb0 258 Pfam PF14581 SseB protein C-terminal domain 137 243 2.2E-28 T 28-03-2018 IPR027945 SseB protein, C-terminal WM46_RS00660 c0ad80203c01334adc80c80ecea44cb0 258 Pfam PF07179 SseB protein N-terminal domain 8 119 2.9E-27 T 28-03-2018 IPR009839 SseB protein N-terminal domain WM46_RS03115 809a6b460ef4cb52124e38f0887ae2d2 276 Pfam PF02498 BRO family, N-terminal domain 23 106 1.1E-14 T 28-03-2018 IPR003497 BRO N-terminal domain WM46_RS03115 809a6b460ef4cb52124e38f0887ae2d2 276 SMART SM01040 16 106 2.2E-19 T 28-03-2018 IPR003497 BRO N-terminal domain WM46_RS11195 1b34e245c0c68d24e369f9649be7906d 110 Pfam PF13982 YbfN-like lipoprotein 20 107 8.4E-49 T 28-03-2018 IPR025727 YbfN-like lipoprotein WM46_RS20830 d952a39b0def893738e994bb2d269b85 374 Pfam PF12698 ABC-2 family transporter protein 27 363 1.2E-31 T 28-03-2018 WM46_RS20830 d952a39b0def893738e994bb2d269b85 374 Gene3D G3DSA:3.40.1710.10 44 193 1.4E-20 T 28-03-2018 WM46_RS12980 7b13718b3243e7bd88eb12a0f860a04c 106 Pfam PF07769 psiF repeat 71 103 6.1E-17 T 28-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat WM46_RS12980 7b13718b3243e7bd88eb12a0f860a04c 106 Pfam PF07769 psiF repeat 27 59 1.0E-18 T 28-03-2018 IPR011690 Phosphate-starvation-induced PsiF repeat WM46_RS15595 1d1d96020ad0d3b227b14e3851bd3500 382 SUPERFAMILY SSF52540 13 57 1.01E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15595 1d1d96020ad0d3b227b14e3851bd3500 382 SUPERFAMILY SSF52540 107 231 1.01E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS15595 1d1d96020ad0d3b227b14e3851bd3500 382 Gene3D G3DSA:3.40.50.300 3 190 6.6E-6 T 28-03-2018 WM46_RS14950 6e21e17412b0cbd9e15e03fadd1a26c6 192 Pfam PF12822 ECF transporter, substrate-specific component 10 173 3.0E-11 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 WM46_RS08150 279728ae192b23f8087867b6e00af9a9 114 Gene3D G3DSA:3.30.1450.10 29 103 1.4E-5 T 28-03-2018 WM46_RS08150 279728ae192b23f8087867b6e00af9a9 114 Pfam PF04355 SmpA / OmlA family 33 96 4.3E-11 T 28-03-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 WM46_RS09315 e879da9c45dae16c25e02de8c3fa2035 445 Pfam PF13440 Polysaccharide biosynthesis protein 44 346 1.2E-8 T 28-03-2018 WM46_RS20610 bf9cabb00daea2a118ea0f68a15f84f5 300 Gene3D G3DSA:1.10.3720.10 19 287 3.4E-47 T 28-03-2018 WM46_RS20610 bf9cabb00daea2a118ea0f68a15f84f5 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 299 2.9E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20610 bf9cabb00daea2a118ea0f68a15f84f5 300 SUPERFAMILY SSF161098 93 280 6.02E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS20610 bf9cabb00daea2a118ea0f68a15f84f5 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 69 3.7E-16 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain WM46_RS23770 5d36bf4b0fa03c6518130f2b1b355744 85 Pfam PF11823 Protein of unknown function (DUF3343) 3 52 6.3E-12 T 28-03-2018 IPR021778 Domain of unknown function DUF3343 WM46_RS06320 a2ab4a4d758768cda6573dcdaa29a7f5 201 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 199 32.799 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 WM46_RS06320 a2ab4a4d758768cda6573dcdaa29a7f5 201 SUPERFAMILY SSF52218 1 199 2.18E-58 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS06320 a2ab4a4d758768cda6573dcdaa29a7f5 201 Pfam PF02525 Flavodoxin-like fold 3 195 4.7E-46 T 28-03-2018 IPR003680 Flavodoxin-like fold WM46_RS06320 a2ab4a4d758768cda6573dcdaa29a7f5 201 Gene3D G3DSA:3.40.50.360 2 201 1.2E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain WM46_RS15650 8fbcdb2c212f234c8560fa534a64c7e4 82 Pfam PF10387 Protein of unknown function (DUF2442) 5 71 7.8E-19 T 28-03-2018 IPR018841 Protein of unknown function DUF2442 WM46_RS20060 8e916a3f57053d85d6122410f5cdd389 463 Pfam PF00860 Permease family 34 426 1.7E-110 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS20060 8e916a3f57053d85d6122410f5cdd389 463 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 29 457 6.4E-142 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS20060 8e916a3f57053d85d6122410f5cdd389 463 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 375 395 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 WM46_RS04655 2d84a522f993ffa944ccbd98cdc7bed3 162 Pfam PF10045 Uncharacterized conserved protein (DUF2280) 1 102 1.4E-49 T 28-03-2018 IPR018738 Protein of unknown function DUF2280 WM46_RS13265 d67eead0f8efb9ff04872e23aa1d4e4c 342 SUPERFAMILY SSF81345 8 339 3.53E-68 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS13265 d67eead0f8efb9ff04872e23aa1d4e4c 342 Gene3D G3DSA:1.10.3470.10 8 342 1.4E-58 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS13265 d67eead0f8efb9ff04872e23aa1d4e4c 342 Pfam PF01032 FecCD transport family 24 338 3.9E-82 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS18900 8052cf4957ceaca6d8f391ce4b9b329b 89 ProDom PD029038 YIHD CYTOPLASMIC ENZYME Y3814 GLYCOGEN YPO0013A HI0845 DIRECT ORF1 UNCHARACTERIZED 1 87 2.0E-44 T 28-03-2018 IPR009383 Protein of unknown function DUF1040 WM46_RS18900 8052cf4957ceaca6d8f391ce4b9b329b 89 Pfam PF06288 Protein of unknown function (DUF1040) 1 86 1.4E-46 T 28-03-2018 IPR009383 Protein of unknown function DUF1040 WM46_RS17195 7ca8dfe17496e5273617baa0bc28f159 334 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 2 334 54.293 T 28-03-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 WM46_RS17195 7ca8dfe17496e5273617baa0bc28f159 334 SUPERFAMILY SSF56524 75 330 4.97E-92 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 WM46_RS17195 7ca8dfe17496e5273617baa0bc28f159 334 Pfam PF00174 Oxidoreductase molybdopterin binding domain 108 267 4.7E-29 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 WM46_RS17195 7ca8dfe17496e5273617baa0bc28f159 334 Gene3D G3DSA:3.90.420.10 64 334 1.1E-62 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 WM46_RS10040 6de07de91f110d6e0f757f2a55fcde3f 316 Pfam PF04393 Protein of unknown function (DUF535) 34 310 1.9E-100 T 28-03-2018 IPR007488 Protein of unknown function DUF535 WM46_RS22530 5043be74522c838b22f0dc2514e6c9c9 356 Gene3D G3DSA:1.25.40.10 56 278 1.8E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS22530 5043be74522c838b22f0dc2514e6c9c9 356 SUPERFAMILY SSF48452 64 228 2.78E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 WM46_RS17295 2f56ee4956fec43702bd13f97b8ac995 367 Gene3D G3DSA:1.10.3720.10 34 365 6.4E-33 T 28-03-2018 WM46_RS17295 2f56ee4956fec43702bd13f97b8ac995 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 174 360 7.1E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS17295 2f56ee4956fec43702bd13f97b8ac995 367 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 156 252 6.3E-20 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 WM46_RS17295 2f56ee4956fec43702bd13f97b8ac995 367 SUPERFAMILY SSF161098 154 346 1.57E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 WM46_RS21465 fcf260a4f8693e022c301b7d5cf0fb5d 312 Pfam PF01758 Sodium Bile acid symporter family 36 213 7.1E-41 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 WM46_RS23875 34aa034e3dd4476fc3ec95a89aa6e063 54 Pfam PF06568 Domain of unknown function (DUF1127) 18 53 2.6E-12 T 28-03-2018 IPR009506 Protein of unknown function DUF1127 WM46_RS24750 6bddccc7abb402700339298ac6f9e337 409 Pfam PF03222 Tryptophan/tyrosine permease family 16 379 1.2E-7 T 28-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 WM46_RS23865 2141ff02388432352e3155c9015d8ca7 137 Gene3D G3DSA:1.10.10.60 83 137 1.5E-5 T 28-03-2018 WM46_RS17105 0d6bb97128dc6219e2325da3f3e305b5 655 Pfam PF04632 Fusaric acid resistance protein family 11 654 2.3E-163 T 28-03-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 WM46_RS17105 0d6bb97128dc6219e2325da3f3e305b5 655 Hamap MF_01545 p-hydroxybenzoic acid efflux pump subunit AaeB [aaeB]. 3 653 54.966 T 28-03-2018 IPR023706 Para-hydroxybenzoic acid efflux pump, subunit AaeB GO:0005886|GO:0006810 WM46_RS09220 cbc209f57c3c82dbc887180868e7636c 168 Gene3D G3DSA:3.40.30.10 29 155 3.9E-23 T 28-03-2018 WM46_RS09220 cbc209f57c3c82dbc887180868e7636c 168 SUPERFAMILY SSF52833 13 156 3.94E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold WM46_RS09220 cbc209f57c3c82dbc887180868e7636c 168 Pfam PF08534 Redoxin 41 148 9.3E-15 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 WM46_RS10955 8cc7b3a353b14a26249f31db6b596840 448 Pfam PF01758 Sodium Bile acid symporter family 96 262 2.1E-27 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 WM46_RS22295 24fa29bb4c1c3f6faddfda07a082beee 176 TIGRFAM TIGR03765 ICE_PFL_4695: integrating conjugative element protein, PFL_4695 family 72 176 1.5E-40 T 28-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 WM46_RS22295 24fa29bb4c1c3f6faddfda07a082beee 176 Pfam PF11072 Protein of unknown function (DUF2859) 31 174 1.1E-47 T 28-03-2018 IPR021300 Integrating conjugative element protein, PFL4695 WM46_RS22195 2ad0732cbbf899d0354b7a51270fde06 165 Pfam PF12101 Protein of unknown function (DUF3577) 19 147 9.1E-49 T 28-03-2018 IPR021960 Protein of unknown function DUF3577 WM46_RS25995 0cbc2ba31c1e58b145819115c63bbbce 237 Pfam PF07996 Type IV secretion system proteins 25 215 6.1E-35 T 28-03-2018 IPR014158 Type IV secretion system, VirB5 WM46_RS25995 0cbc2ba31c1e58b145819115c63bbbce 237 SUPERFAMILY SSF101082 25 217 4.58E-40 T 28-03-2018 IPR023220 Type IV secretion system, VirB5-domain WM46_RS25995 0cbc2ba31c1e58b145819115c63bbbce 237 Gene3D G3DSA:1.20.58.430 25 218 2.7E-37 T 28-03-2018 WM46_RS08430 27de9e0f8e9b3a38e02829d1653f192f 82 Pfam PF04226 Transglycosylase associated protein 33 81 1.8E-17 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 WM46_RS20870 16504ca63089732a9bdcd9687e91ff01 146 Pfam PF15596 Immunity protein 57 2 107 1.3E-43 T 28-03-2018 IPR028955 Immunity protein 57 WM46_RS15785 ded6e7e6154dab712d1e93ff55b2a56e 641 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 139 6.0E-16 T 28-03-2018 WM46_RS15785 ded6e7e6154dab712d1e93ff55b2a56e 641 Gene3D G3DSA:3.30.565.10 7 400 3.0E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS15785 ded6e7e6154dab712d1e93ff55b2a56e 641 SUPERFAMILY SSF55874 12 177 6.4E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain WM46_RS19590 0606db3d399ac6007e7b51b6f5ecd177 249 Gene3D G3DSA:3.90.470.20 10 140 4.4E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 WM46_RS06075 d0fda8c27a49b1f42c79bc38e1c4344a 222 Pfam PF04012 PspA/IM30 family 2 216 1.1E-48 T 28-03-2018 IPR007157 PspA/IM30 WM46_RS06075 d0fda8c27a49b1f42c79bc38e1c4344a 222 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 218 3.2E-92 T 28-03-2018 IPR014319 Phage shock protein, PspA WM46_RS06075 d0fda8c27a49b1f42c79bc38e1c4344a 222 Gene3D G3DSA:1.20.1170.10 4 222 1.1E-4 T 28-03-2018 WM46_RS24120 28a10d9413db227ce0c3ceda384c88d9 214 Gene3D G3DSA:3.30.450.20 31 159 8.0E-6 T 28-03-2018 WM46_RS24120 28a10d9413db227ce0c3ceda384c88d9 214 Pfam PF10144 Bacterial virulence factor haemolysin 1 160 3.5E-65 T 28-03-2018 IPR019305 Uncharacterised protein family Smp WM46_RS02915 0115bea2f16bff36302c70f6c1d58b97 232 Pfam PF02348 Cytidylyltransferase 5 172 6.8E-25 T 28-03-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 WM46_RS02915 0115bea2f16bff36302c70f6c1d58b97 232 Gene3D G3DSA:3.90.550.10 3 232 3.1E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS02915 0115bea2f16bff36302c70f6c1d58b97 232 SUPERFAMILY SSF53448 3 224 4.35E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases WM46_RS18620 f9a594c849f8355046a3f5347e72f950 219 Pfam PF03591 AzlC protein 19 154 5.0E-30 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease WM46_RS12930 c9e74e6e4b850db5ca9bd3363e163d18 389 Pfam PF07690 Major Facilitator Superfamily 8 329 4.3E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 WM46_RS12930 c9e74e6e4b850db5ca9bd3363e163d18 389 Gene3D G3DSA:1.20.1250.20 191 381 4.7E-12 T 28-03-2018 WM46_RS12930 c9e74e6e4b850db5ca9bd3363e163d18 389 Gene3D G3DSA:1.20.1250.20 1 190 3.8E-27 T 28-03-2018 WM46_RS12930 c9e74e6e4b850db5ca9bd3363e163d18 389 SUPERFAMILY SSF103473 3 381 8.5E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain WM46_RS04915 27cef201c4de6a19fc03d7797143868d 47 Pfam PF10736 Protein of unknown function (DUF2627) 1 38 3.1E-28 T 28-03-2018 IPR019672 Protein of unknown function DUF2627 WM46_RS01515 72e2b219b408080fa09ae3d30c1f2e6b 269 Pfam PF01925 Sulfite exporter TauE/SafE 18 253 1.8E-43 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 WM46_RS07390 f28143c4da8db18fda12fc566a159a32 493 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 480 1.3E-134 T 28-03-2018 IPR010352 Protein of unknown function DUF945 WM46_RS10180 eebbcc13ed1d77a980311714a6000629 95 Pfam PF07214 Protein of unknown function (DUF1418) 2 92 1.9E-35 T 28-03-2018 IPR010815 Protein of unknown function DUF1418 WM46_RS12445 26bc55615ccf8540370ff7cb573913e2 124 Pfam PF10757 Biofilm formation regulator YbaJ 1 116 3.8E-64 T 28-03-2018 IPR019693 Biofilm formation regulator YbaJ WM46_RS06620 38d4aa0b5d488c486f33f12acba7dc6b 149 Pfam PF04657 Putative inner membrane exporter, YdcZ 6 143 3.0E-20 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ WM46_RS21795 8cd3a549ef252f6c215dbb4080d07133 167 TIGRFAM TIGR03147 cyt_nit_nrfF: cytochrome c nitrite reductase, accessory protein NrfF 38 159 1.2E-60 T 28-03-2018 IPR017565 Formate-dependent nitrite reductase complex, subunit NrfF WM46_RS21795 8cd3a549ef252f6c215dbb4080d07133 167 Pfam PF03918 Cytochrome C biogenesis protein 40 164 1.6E-44 T 28-03-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family WM46_RS08800 7a892355a358d81f5da161fa46dbbaee 218 Pfam PF13144 Chaperone for flagella basal body P-ring formation 28 214 1.4E-36 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal WM46_RS08800 7a892355a358d81f5da161fa46dbbaee 218 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 83 216 1.9E-38 T 28-03-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal WM46_RS08800 7a892355a358d81f5da161fa46dbbaee 218 Gene3D G3DSA:3.90.1210.10 92 157 3.0E-9 T 28-03-2018 WM46_RS08800 7a892355a358d81f5da161fa46dbbaee 218 SMART SM00858 94 156 5.8E-9 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 WM46_RS02360 5f16bdb158ad86b447a69ae7f55a6fc7 84 Pfam PF03692 Putative zinc- or iron-chelating domain 2 60 3.0E-6 T 28-03-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein WM46_RS05885 3141503591bfd12eb0a1f6f66ffe3a9a 83 Pfam PF10692 Protein of unknown function (DUF2498) 4 81 2.6E-42 T 28-03-2018 IPR019633 Protein of unknown function DUF2498 WM46_RS07020 a3fd4b9b2f1bf54e5a6dad10d76c4579 304 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 280 2.3E-59 T 28-03-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 WM46_RS25605 f41cb10624afa6f60d4f3cbcd2f9eb01 111 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 104 1.4E-14 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD WM46_RS22240 cdaa02676237ca0f14a3f1f7e01cb1ca 169 TIGRFAM TIGR03021 pilP_fam: type IV pilus biogenesis protein PilP 42 162 1.0E-23 T 28-03-2018 IPR022753 Type IV pilus biogenesis PilP WM46_RS23210 cc1c17f7f14a747227b8c3b32191e199 99 TIGRFAM TIGR03578 EF_0831: conserved hypothetical protein EF_0831/AHA_3912 2 96 4.1E-42 T 28-03-2018 IPR020037 Protein of unknown function DUF4312 WM46_RS23210 cc1c17f7f14a747227b8c3b32191e199 99 Pfam PF14189 Domain of unknown function (DUF4312) 5 88 7.4E-35 T 28-03-2018 IPR020037 Protein of unknown function DUF4312 WM46_RS14285 3946d391cf0157e761d3b1bcd97f1dad 284 Pfam PF17113 Regulatory signalling modulator protein AmpE 1 284 1.7E-156 T 28-03-2018 IPR031347 Protein AmpE WM46_RS23780 60057acdbd261d741ab8149958143e31 383 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 40 383 3.8E-81 T 28-03-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit WM46_RS05255 3be7c0d4c38d490edadcf2165aac6b37 217 PIRSF PIRSF006324 1 209 3.0E-48 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS05255 3be7c0d4c38d490edadcf2165aac6b37 217 Pfam PF01810 LysE type translocator 18 207 5.1E-30 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 WM46_RS01275 a2471203040b7db3fd39330994ea7500 515 Gene3D G3DSA:1.10.10.10 80 143 0.009 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01275 a2471203040b7db3fd39330994ea7500 515 Gene3D G3DSA:1.10.10.10 6 65 6.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS01275 a2471203040b7db3fd39330994ea7500 515 Gene3D G3DSA:1.10.1790.10 279 384 0.013 T 28-03-2018 IPR011608 PRD domain GO:0006355 WM46_RS21065 34a8603c11122537ee3ff49280928ad3 119 Pfam PF07226 Protein of unknown function (DUF1422) 3 114 9.9E-54 T 28-03-2018 IPR009867 Protein of unknown function DUF1422 WM46_RS21065 34a8603c11122537ee3ff49280928ad3 119 ProDom PD076479 MEMBRANE INNER YIJD TRANSMEMBRANE Y0323 AAA SIMILAR A ACETYL-COENZYME VV0128 1 119 7.0E-60 T 28-03-2018 IPR009867 Protein of unknown function DUF1422 WM46_RS01415 f5fb78fdc838d9ab15ba7a894ef4b054 154 Pfam PF04191 Phospholipid methyltransferase 40 141 1.5E-13 T 28-03-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 WM46_RS06025 e2b0bcefee8b8a7f80ce3f0d82591d0f 370 SUPERFAMILY SSF49401 185 370 9.94E-8 T 28-03-2018 IPR008966 Adhesion domain WM46_RS06025 e2b0bcefee8b8a7f80ce3f0d82591d0f 370 Gene3D G3DSA:2.60.40.1090 176 370 1.3E-17 T 28-03-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 WM46_RS08365 990ee3a1a88d8301a559044916510b0b 427 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 423 42.435 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 WM46_RS08365 990ee3a1a88d8301a559044916510b0b 427 Pfam PF04285 Protein of unknown function (DUF444) 4 421 1.5E-186 T 28-03-2018 IPR006698 Uncharacterised protein family UPF0229 WM46_RS00960 fed49b75f323bfa49522a80695cd3d05 230 Pfam PF06249 Ethanolamine utilisation protein EutQ 82 229 5.0E-65 T 28-03-2018 IPR010424 Ethanolamine utilisation EutQ WM46_RS00960 fed49b75f323bfa49522a80695cd3d05 230 SUPERFAMILY SSF51182 106 227 2.08E-28 T 28-03-2018 IPR011051 RmlC-like cupin domain WM46_RS00960 fed49b75f323bfa49522a80695cd3d05 230 Gene3D G3DSA:2.60.120.10 87 230 7.5E-32 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS23765 c3dcf2482cc059f5a258d2f80bbd6f0a 273 Gene3D G3DSA:2.120.10.30 12 270 2.2E-12 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like WM46_RS23765 c3dcf2482cc059f5a258d2f80bbd6f0a 273 SUPERFAMILY SSF50956 29 270 6.02E-35 T 28-03-2018 WM46_RS23765 c3dcf2482cc059f5a258d2f80bbd6f0a 273 Pfam PF06977 SdiA-regulated 25 268 1.9E-85 T 28-03-2018 IPR009722 SdiA-regulated WM46_RS14795 28a71dd32779f8c7bb3b440e448bc1e0 257 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 37.814 T 28-03-2018 IPR005583 Peroxide stress protein YaaA WM46_RS14795 28a71dd32779f8c7bb3b440e448bc1e0 257 Pfam PF03883 Peroxide stress protein YaaA 1 243 1.7E-91 T 28-03-2018 IPR005583 Peroxide stress protein YaaA WM46_RS20100 3d22a042f1e1cad585a2894b2595acfe 205 Pfam PF03458 UPF0126 domain 5 79 1.1E-18 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 WM46_RS20100 3d22a042f1e1cad585a2894b2595acfe 205 Pfam PF03458 UPF0126 domain 91 164 6.0E-22 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 WM46_RS01695 58f7eea5dc1bb9c948282676388755dc 463 Pfam PF03611 PTS system sugar-specific permease component 12 408 5.0E-150 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 WM46_RS04435 4ad98a2d8aae980c41392a9b149b50bc 104 Pfam PF13973 Domain of unknown function (DUF4222) 3 52 2.6E-16 T 28-03-2018 IPR025317 Protein of unknown function DUF4222 WM46_RS06980 320b2a99e2abc0db7cc9160e605a1c44 191 TIGRFAM TIGR04402 mob_CxxC_CxxC: mobilome CxxCx(11)CxxC protein 8 188 1.0E-19 T 28-03-2018 IPR030914 Mobilome CxxCx(11)CxxC protein WM46_RS08860 f3b8597e7009ba3a54c36db54ab3aa64 84 ProDom PD060858 YCEP CYTOPLASMIC STY1199 ESCHERICHIA COLI SIMILAR ECS1438 1 84 1.0E-43 T 28-03-2018 IPR025730 Biofilm regulator BssS WM46_RS08860 f3b8597e7009ba3a54c36db54ab3aa64 84 Pfam PF13991 BssS protein family 11 81 5.8E-32 T 28-03-2018 IPR025730 Biofilm regulator BssS WM46_RS12415 61606eb0354f18a7f96473dd8104dc4b 53 Pfam PF10689 Protein of unknown function (DUF2496) 2 44 1.0E-23 T 28-03-2018 IPR019630 Protein of unknown function DUF2496, YbaM-related WM46_RS03735 85a197310de71a19a5a7fe0c82be6cef 306 SUPERFAMILY SSF103481 43 144 8.76E-11 T 28-03-2018 WM46_RS03735 85a197310de71a19a5a7fe0c82be6cef 306 Pfam PF00892 EamA-like transporter family 13 140 1.6E-22 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS03735 85a197310de71a19a5a7fe0c82be6cef 306 Pfam PF00892 EamA-like transporter family 150 284 2.0E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 WM46_RS03735 85a197310de71a19a5a7fe0c82be6cef 306 SUPERFAMILY SSF103481 187 287 1.44E-11 T 28-03-2018 WM46_RS09300 39678060ab293cc8da170d9e87710a35 244 SUPERFAMILY SSF52540 7 224 6.14E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase WM46_RS09300 39678060ab293cc8da170d9e87710a35 244 Gene3D G3DSA:3.40.50.300 6 228 3.1E-16 T 28-03-2018 WM46_RS10070 0aae6268268e74d44cc2dbd904a7f1bf 144 Pfam PF07681 DoxX 21 98 1.9E-18 T 28-03-2018 IPR032808 DoxX family WM46_RS13310 fb901fdf4a1b598711bf765347dbd6c2 337 Pfam PF01032 FecCD transport family 22 331 3.5E-82 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 WM46_RS13310 fb901fdf4a1b598711bf765347dbd6c2 337 SUPERFAMILY SSF81345 16 331 5.49E-70 T 28-03-2018 IPR029022 ABC transporter, BtuC-like WM46_RS13310 fb901fdf4a1b598711bf765347dbd6c2 337 Gene3D G3DSA:1.10.3470.10 8 337 9.4E-57 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS07970 848813e1caf5538b439fde122732af34 60 Gene3D G3DSA:2.10.70.10 24 60 1.6E-16 T 28-03-2018 WM46_RS07970 848813e1caf5538b439fde122732af34 60 Pfam PF10636 Hemin uptake protein hemP 25 60 8.1E-16 T 28-03-2018 IPR019600 Hemin uptake protein HemP WM46_RS16415 83612677593d78f6cc3b579562364efa 220 Pfam PF09335 SNARE associated Golgi protein 48 174 3.7E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS25985 d32b9ebdbd99f1ded7679c9cc34eb0b8 105 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 7 79 2.8E-17 T 28-03-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB WM46_RS11790 de9ee3633b1fd45c485e109027f6e0bc 341 SUPERFAMILY SSF51658 7 323 8.15E-58 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS11790 de9ee3633b1fd45c485e109027f6e0bc 341 Gene3D G3DSA:3.20.20.150 6 334 3.7E-46 T 28-03-2018 WM46_RS11790 de9ee3633b1fd45c485e109027f6e0bc 341 Pfam PF07582 AP endonuclease family 2 C terminus 280 334 3.4E-20 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal WM46_RS11790 de9ee3633b1fd45c485e109027f6e0bc 341 Pfam PF01261 Xylose isomerase-like TIM barrel 30 279 1.0E-33 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain WM46_RS15755 323b63866557f9c90ce5995c4ccdadf3 365 Gene3D G3DSA:3.90.20.10 2 126 0.018 T 28-03-2018 WM46_RS05595 2a14fcbbf3be7d1049c4a8a8a0b22b72 81 SUPERFAMILY SSF141099 1 80 1.1E-24 T 28-03-2018 IPR015073 Atu1913-like WM46_RS05595 2a14fcbbf3be7d1049c4a8a8a0b22b72 81 Pfam PF08980 Domain of unknown function (DUF1883) 12 78 5.8E-7 T 28-03-2018 IPR015073 Atu1913-like WM46_RS05595 2a14fcbbf3be7d1049c4a8a8a0b22b72 81 Gene3D G3DSA:4.10.1210.10 1 81 4.4E-20 T 28-03-2018 IPR015073 Atu1913-like WM46_RS10370 dca832059b49f45ac8662de3416b3d2b 369 Pfam PF03600 Citrate transporter 23 304 5.7E-26 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 WM46_RS01555 f3f21e4e4f24a56b913e8064d6be6f16 333 PIRSF PIRSF020588 1 333 4.0E-165 T 28-03-2018 IPR023597 Flagellar regulator Flk GO:0010468|GO:0031224 WM46_RS07010 3531204ce3135a66c7dad2e17d0e49ff 160 Pfam PF07180 CaiF/GrlA transcriptional regulator 17 141 9.7E-12 T 28-03-2018 IPR020357 Transcription regulator CaiF/GrlA GO:0006351 WM46_RS18625 65b798c219cff652de8f3442209cc341 107 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 102 3.3E-12 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD WM46_RS14660 5be3a570d6b76f643d6c633803ec43c3 129 ProDom PD081346 TRANSCRIPTIONAL CAIF OPERON REGULATOR CAI ACTIVATOR TRANSCRIPTION ACTIVATORY FIX REGULATION 1 129 6.0E-55 T 28-03-2018 IPR020357 Transcription regulator CaiF/GrlA GO:0006351 WM46_RS14660 5be3a570d6b76f643d6c633803ec43c3 129 Pfam PF07180 CaiF/GrlA transcriptional regulator 4 64 8.7E-7 T 28-03-2018 IPR020357 Transcription regulator CaiF/GrlA GO:0006351 WM46_RS15810 f573a5434fd2b569ea254c0b8053532f 128 Pfam PF11682 Probable zinc-ribbon 4 122 6.4E-20 T 28-03-2018 IPR021696 Protein of unknown function DUF3279 WM46_RS16380 b7035a401fdd6617ad951deaf902e5b4 321 Pfam PF03741 Integral membrane protein TerC family 80 282 2.4E-56 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 WM46_RS16380 b7035a401fdd6617ad951deaf902e5b4 321 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 7 311 2.0E-120 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 WM46_RS25610 dffa6586ef6d71d1afa923300cedce5b 245 Pfam PF03591 AzlC protein 24 165 3.5E-38 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease WM46_RS17940 54f9a56e64d3d1de8d3784f4f30f4987 446 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 6 360 2.4E-132 T 28-03-2018 IPR010839 Acyclic terpene utilisation WM46_RS06460 b0343d744cb3c2cf23a82076783acf03 437 PIRSF PIRSF006304 1 437 6.6E-159 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 WM46_RS06460 b0343d744cb3c2cf23a82076783acf03 437 TIGRFAM TIGR00827 EIIC-GAT: PTS system, galactitol-specific IIC component 5 410 2.1E-210 T 28-03-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 WM46_RS06460 b0343d744cb3c2cf23a82076783acf03 437 Pfam PF03611 PTS system sugar-specific permease component 4 385 8.7E-67 T 28-03-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 WM46_RS22650 81c6cb08a9d963b75b23b30c4e473527 405 Gene3D G3DSA:2.40.160.60 28 403 4.9E-32 T 28-03-2018 WM46_RS22650 81c6cb08a9d963b75b23b30c4e473527 405 Pfam PF13729 F plasmid transfer operon, TraF, protein 54 323 4.4E-74 T 28-03-2018 IPR032811 Putative conjugal transfer protein TraF-related WM46_RS09270 8b2b30b3261450c3e7f6be2a3ebe6063 329 Pfam PF05035 2-keto-3-deoxy-galactonokinase 7 295 2.3E-46 T 28-03-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 WM46_RS09270 8b2b30b3261450c3e7f6be2a3ebe6063 329 Gene3D G3DSA:3.30.420.40 1 156 2.8E-8 T 28-03-2018 WM46_RS09270 8b2b30b3261450c3e7f6be2a3ebe6063 329 SUPERFAMILY SSF53067 1 84 6.69E-5 T 28-03-2018 WM46_RS17400 5a041cdbf5526542a42c4c80ace67de6 72 Pfam PF03889 Domain of unknown function 9 45 3.9E-22 T 28-03-2018 IPR005589 Protein of unknown function DUF331 WM46_RS18590 92f273fb3c27089d519b6fead6016966 334 Gene3D G3DSA:1.10.3470.10 4 311 5.3E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like WM46_RS18590 92f273fb3c27089d519b6fead6016966 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 305 4.5E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 WM46_RS05480 cb8145caa10ed142c196169643c8480e 92 Pfam PF10762 Protein of unknown function (DUF2583) 1 87 1.2E-47 T 28-03-2018 IPR019698 Protein of unknown function DUF2583 WM46_RS16015 3b72d590f44c997ea1b93fb04df9b1a2 219 Pfam PF09335 SNARE associated Golgi protein 48 173 6.7E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS08900 18a873c67ae627795d2c9b0ff8e22c20 124 Pfam PF13984 MsyB protein 3 124 9.3E-65 T 28-03-2018 IPR025729 MsyB protein WM46_RS11155 71ce84afdf6550edcff3916935870f0c 257 Gene3D G3DSA:3.40.50.1820 1 254 1.0E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS11155 71ce84afdf6550edcff3916935870f0c 257 Pfam PF12697 Alpha/beta hydrolase family 19 246 1.3E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 WM46_RS11155 71ce84afdf6550edcff3916935870f0c 257 SUPERFAMILY SSF53474 12 253 2.57E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold WM46_RS18145 1bb4bc470df7b7303e2bfee738bbbcb7 680 Pfam PF09972 Predicted membrane protein (DUF2207) 51 608 3.0E-68 T 28-03-2018 IPR018702 Protein of unknown function DUF2207, membrane WM46_RS19365 3a3a8c71c4b884bed8e9dcb23e1b878c 112 Pfam PF04219 Protein of unknown function, DUF 10 98 1.3E-38 T 28-03-2018 IPR007335 Protein of unknown function DUF413 WM46_RS01295 45ca5616a85de1cd86184c79ff7c8067 108 Pfam PF10697 Protein of unknown function (DUF2502) 23 106 1.7E-19 T 28-03-2018 IPR019638 Protein of unknown function DUF2502 WM46_RS12460 269f203a95a6f708f97b5e0cde91fd69 156 Pfam PF10777 Inner membrane protein YlaC 1 152 3.0E-67 T 28-03-2018 IPR019713 Inner membrane protein YlaC WM46_RS26230 e77859230364ac288993571001464256 141 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 45 141 2.0E-52 T 28-03-2018 IPR004914 Antirestriction protein WM46_RS26230 e77859230364ac288993571001464256 141 Pfam PF03230 Antirestriction protein 44 141 8.9E-15 T 28-03-2018 IPR004914 Antirestriction protein WM46_RS21720 98f6d83fd829857c54e80ef55c1bad3a 449 Pfam PF00860 Permease family 26 409 1.2E-84 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 WM46_RS05350 0f3648097f7d6e835db745f7ad71c0ac 926 Gene3D G3DSA:3.40.50.300 204 577 2.1E-4 T 28-03-2018 WM46_RS25060 33ed880f62dba55158ed3107f9473fde 181 Pfam PF07348 Syd protein (SUKH-2) 8 179 3.8E-68 T 28-03-2018 IPR009948 Syd GO:0009898 WM46_RS25060 33ed880f62dba55158ed3107f9473fde 181 Hamap MF_01104 Protein Syd [syd]. 3 181 34.505 T 28-03-2018 IPR009948 Syd GO:0009898 WM46_RS04780 325a25012283db8e5ac9eec49dfc7a9b 317 Pfam PF09397 Ftsk gamma domain 18 78 2.0E-20 T 28-03-2018 IPR018541 FtsK gamma domain WM46_RS04780 325a25012283db8e5ac9eec49dfc7a9b 317 SMART SM00843 16 81 1.1E-24 T 28-03-2018 IPR018541 FtsK gamma domain WM46_RS04780 325a25012283db8e5ac9eec49dfc7a9b 317 Gene3D G3DSA:1.10.10.10 18 72 2.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04780 325a25012283db8e5ac9eec49dfc7a9b 317 SUPERFAMILY SSF46785 17 81 5.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain WM46_RS04145 f2206ac053a0247aae229f6fc4140e0f 180 SMART SM00972 119 177 2.4E-9 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS04145 f2206ac053a0247aae229f6fc4140e0f 180 Pfam PF05229 Spore Coat Protein U domain 35 177 1.6E-23 T 28-03-2018 IPR007893 Spore coat protein U WM46_RS03330 1100880c7713a7cfc299895d3320fe74 92 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 11 88 4.0E-8 T 28-03-2018 IPR019289 Bacteriophage tail protein Gp41, putative WM46_RS08245 8bd77de7da72bfda58d728611c4393de 91 Pfam PF07383 Protein of unknown function (DUF1496) 35 90 5.1E-25 T 28-03-2018 IPR009971 Protein of unknown function DUF1496 WM46_RS08330 8c4f160021c42a56461a212ed93c7a46 91 Pfam PF07023 Protein of unknown function (DUF1315) 5 79 2.1E-26 T 28-03-2018 IPR009749 Protein of unknown function DUF1315 WM46_RS15385 f9112023488cf31bce532a95f47b0f32 307 Pfam PF13737 Transposase DDE domain 19 130 1.4E-43 T 28-03-2018 IPR025668 Transposase DDE domain WM46_RS24575 7c3b9770c51738e5f1d24bbb532231f9 587 SUPERFAMILY SSF53649 442 474 4.71E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS24575 7c3b9770c51738e5f1d24bbb532231f9 587 SUPERFAMILY SSF53649 3 388 4.71E-61 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 WM46_RS24575 7c3b9770c51738e5f1d24bbb532231f9 587 Gene3D G3DSA:3.40.720.10 2 357 1.3E-51 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 WM46_RS24575 7c3b9770c51738e5f1d24bbb532231f9 587 Pfam PF00884 Sulfatase 3 338 9.1E-29 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 WM46_RS00925 a15f638fd0c6b4ccd61ccbbbabb7111e 346 Pfam PF06674 Protein of unknown function (DUF1176) 25 346 7.7E-95 T 28-03-2018 IPR009560 Protein of unknown function DUF1176 WM46_RS18195 fd57d915dcc36d3a75c20504e9234bc0 208 Pfam PF07947 YhhN family 26 206 1.2E-40 T 28-03-2018 IPR012506 YhhN-like GO:0016021 WM46_RS13695 7c06d59c3ee7fa154fd3477512d9c29d 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 19 35 1.0E-35 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS13695 7c06d59c3ee7fa154fd3477512d9c29d 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 119 133 1.0E-35 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS13695 7c06d59c3ee7fa154fd3477512d9c29d 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 68 85 1.0E-35 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS13695 7c06d59c3ee7fa154fd3477512d9c29d 579 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 56 1.0E-35 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS13695 7c06d59c3ee7fa154fd3477512d9c29d 579 Pfam PF00771 FHIPEP family 7 570 4.1E-186 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 WM46_RS12110 c1bbeaba44d3b26126cc8efb7a7add59 115 Pfam PF10721 Protein of unknown function (DUF2514) 10 106 1.2E-23 T 28-03-2018 IPR019659 Protein of unknown function DUF2514 WM46_RS03380 e9c6f6ffd13fb3108b406168d22a5f83 141 Pfam PF02413 Caudovirales tail fibre assembly protein, lambda gpK 25 136 6.5E-24 T 28-03-2018 IPR003458 Bacteriophage T4, Gp38, tail fibre assembly WM46_RS05960 fb93fe3e6215589df18f1c34fe1c88c4 60 Hamap MF_01641 UPF0509 protein YciZ [yciZ]. 1 60 23.998 T 28-03-2018 IPR020887 Uncharacterised protein family UPF0509 WM46_RS17565 106b6b3101112abe19cd43e2fc90fe59 64 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 51 7.1E-15 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain WM46_RS21570 2e955024a1e4032284edb999828e581f 314 Pfam PF07148 Maltose operon periplasmic protein precursor (MalM) 76 209 1.6E-50 T 28-03-2018 IPR010794 Maltose operon periplasmic GO:0008643|GO:0042597 WM46_RS07000 d7cf4ee7590915f8bdb928a37c7ce604 121 SUPERFAMILY SSF54593 17 116 5.63E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase WM46_RS15335 1f5296df8ca78e056696a12f03b5073c 192 Pfam PF13737 Transposase DDE domain 3 88 1.7E-13 T 28-03-2018 IPR025668 Transposase DDE domain WM46_RS04590 6b689d43246369139975d48157cad109 239 Gene3D G3DSA:1.20.120.330 8 234 4.7E-4 T 28-03-2018 WM46_RS22440 b52d10939c04622e9493d1b38e9abc6a 122 Pfam PF13953 PapC C-terminal domain 38 107 5.1E-23 T 28-03-2018 IPR025949 PapC-like, C-terminal domain WM46_RS20470 c4a5e5621f9ab236620b57ddd38e0518 331 Hamap MF_01949 O-acetyltransferase WecH [wecH]. 1 331 38.241 T 28-03-2018 IPR032905 O-acetyltransferase WecH GO:0009246|GO:0016413 WM46_RS20470 c4a5e5621f9ab236620b57ddd38e0518 331 Pfam PF01757 Acyltransferase family 6 321 7.2E-32 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 WM46_RS22270 8a8ff6e17d7e9d085c2f04b5cd300e24 448 Pfam PF04917 Bacterial shufflon protein, N-terminal constant region 42 366 3.6E-128 T 28-03-2018 IPR007001 Bacterial shufflon protein, N-terminal WM46_RS16370 d944dfe99c7f8744af650f4a36a62d7e 167 Pfam PF01863 Protein of unknown function DUF45 93 149 5.7E-11 T 28-03-2018 IPR002725 Protein of unknown function DUF45 WM46_RS25485 8f5c949e7bca641f59280b76c5a1a3f3 119 Pfam PF06923 Glucitol operon activator protein (GutM) 5 110 3.7E-35 T 28-03-2018 IPR009693 Glucitol operon activator WM46_RS25485 8f5c949e7bca641f59280b76c5a1a3f3 119 PIRSF PIRSF011474 1 119 1.1E-45 T 28-03-2018 IPR009693 Glucitol operon activator WM46_RS12865 f314eb62c6caa9f06af8b112d793d487 464 Pfam PF13163 Protein of unknown function (DUF3999) 30 453 9.3E-108 T 28-03-2018 IPR025060 Protein of unknown function DUF3999 WM46_RS06700 f40e77e477e87dd680aa8c3b505d36a2 120 Gene3D G3DSA:3.40.50.10400 1 119 1.5E-20 T 28-03-2018 IPR027269 Hypothetical PA1492 domain WM46_RS21755 a4ae5af78d6b2b304c457aa7b502fbc2 104 Pfam PF04341 Protein of unknown function, DUF485 11 98 2.8E-33 T 28-03-2018 IPR007436 Protein of unknown function DUF485 WM46_RS11850 33967ff8e29997a0dde5f594963ea772 114 Pfam PF11604 Copper binding periplasmic protein CusF 47 108 8.0E-24 T 28-03-2018 IPR021647 Copper binding periplasmic protein CusF WM46_RS15230 68c09ba9ad21ad5862c62b6a66abb22a 339 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 2 326 7.8E-85 T 28-03-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 WM46_RS15230 68c09ba9ad21ad5862c62b6a66abb22a 339 Gene3D G3DSA:1.20.1600.10 1 332 3.6E-57 T 28-03-2018 WM46_RS15230 68c09ba9ad21ad5862c62b6a66abb22a 339 Pfam PF02321 Outer membrane efflux protein 2 111 2.4E-10 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS15230 68c09ba9ad21ad5862c62b6a66abb22a 339 Pfam PF02321 Outer membrane efflux protein 139 324 6.0E-24 T 28-03-2018 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 WM46_RS15230 68c09ba9ad21ad5862c62b6a66abb22a 339 SUPERFAMILY SSF56954 2 329 8.89E-70 T 28-03-2018 WM46_RS25955 e61278fd4153e60b9048c381e7a0cb92 104 Pfam PF07424 TrbM 26 98 7.2E-7 T 28-03-2018 IPR009989 TrbM WM46_RS12035 42934d3cc4a52f252e3c4ae2c8ea393a 205 Pfam PF15977 Winged helix-turn-helix DNA binding 136 202 1.1E-26 T 28-03-2018 WM46_RS12035 42934d3cc4a52f252e3c4ae2c8ea393a 205 Gene3D G3DSA:2.60.120.10 10 133 7.9E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold WM46_RS12035 42934d3cc4a52f252e3c4ae2c8ea393a 205 SUPERFAMILY SSF51206 18 126 1.83E-8 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like WM46_RS07040 5d064a91a446e5eed68c9e7a2f8264ab 119 ProDom PD076485 YNEG CYTOPLASMIC ECS2130 STY1535 1 114 7.0E-45 T 28-03-2018 IPR020378 Protein of unknown function DUF4186 WM46_RS07040 5d064a91a446e5eed68c9e7a2f8264ab 119 Pfam PF13811 Domain of unknown function (DUF4186) 7 112 5.3E-51 T 28-03-2018 IPR020378 Protein of unknown function DUF4186 WM46_RS13000 d46932ca7cbb13360d678d2f3cbae9e3 219 Pfam PF06904 Extensin-like protein C-terminus 46 219 1.7E-52 T 28-03-2018 IPR009683 Extensin-like, C-terminal WM46_RS22400 de062ebba4b8e79452729584dfab7213 550 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 6 237 1.5E-45 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 WM46_RS22400 de062ebba4b8e79452729584dfab7213 550 Hamap MF_01165 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase [arnT]. 1 550 42.591 T 28-03-2018 IPR022839 Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase GO:0016763 WM46_RS07430 449e4444196bf2108ccdaa881b83eeda 146 Pfam PF10754 Protein of unknown function (DUF2569) 7 144 9.0E-42 T 28-03-2018 IPR019690 Protein of unknown function DUF2569 WM46_RS05735 0b5546f98277a654339abe351cebc7ef 215 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 8 206 8.0E-83 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 WM46_RS05735 0b5546f98277a654339abe351cebc7ef 215 Pfam PF01914 MarC family integral membrane protein 9 210 1.6E-73 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 WM46_RS15885 75b571f4b8a9aee1163ad49d068dab58 282 Pfam PF13708 Domain of unknown function (DUF4942) 88 275 1.5E-61 T 28-03-2018 IPR031339 Domain of unknown function DUF4942 WM46_RS22905 b3afd0a674a1d0e713cb7f404f194721 65 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 5 60 2.7E-21 T 28-03-2018 IPR019201 Protein of unknown function DUF2065 WM46_RS22145 2f16d3eeaf81c82cdc4b02d7471b77b9 155 Pfam PF15941 FidL-like putative membrane protein 67 152 8.4E-7 T 28-03-2018 IPR031854 Putative membrane protein FidL-like WM46_RS11345 01ebddbc97d9313aee7d7f697424df3d 160 Pfam PF07295 Zinc-ribbon containing domain 14 157 4.0E-53 T 28-03-2018 IPR009912 Zinc-ribbon containing domain WM46_RS00750 ee320538bbef7e02138c0dcfc5aba3a2 63 Pfam PF11119 Protein of unknown function (DUF2633) 9 62 1.3E-32 T 28-03-2018 IPR022576 Protein of unknown function DUF2633 WM46_RS00750 ee320538bbef7e02138c0dcfc5aba3a2 63 ProDom PD053432 MEMBRANE TRANSMEMBRANE YFGG INNER EXPORTED Y1396 PRECURSOR SIGNAL 1 63 3.0E-27 T 28-03-2018 IPR022576 Protein of unknown function DUF2633 WM46_RS06375 4f46de4a1ce8de1d3728a4f2bb61ea23 91 Pfam PF02583 Metal-sensitive transcriptional repressor 7 82 4.8E-20 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 WM46_RS14240 a9b403228e6e68066bae5e3201b32d6d 549 Pfam PF11737 Protein of unknown function (DUF3300) 62 342 1.4E-86 T 28-03-2018 IPR021728 Protein of unknown function DUF3300 WM46_RS04630 82116515022492205e17db4e257fb24a 109 TIGRFAM TIGR01594 holin_lambda: phage holin, lambda family 1 106 4.6E-42 T 28-03-2018 IPR006481 Bacteriophage lambda, GpS, holin WM46_RS04630 82116515022492205e17db4e257fb24a 109 Pfam PF05106 Phage holin family (Lysis protein S) 3 101 5.4E-34 T 28-03-2018 IPR006481 Bacteriophage lambda, GpS, holin WM46_RS00100 e6f67b0d679c811f844f7308218c3d7f 87 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 23 85 1.8E-5 T 28-03-2018 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 WM46_RS14505 74b4dcaf5642d043962079d8005e304e 255 Pfam PF09335 SNARE associated Golgi protein 36 159 4.0E-19 T 28-03-2018 IPR032816 SNARE associated Golgi protein WM46_RS23750 352235d23222cacfba2224c41179363b 66 Gene3D G3DSA:1.10.1220.10 10 62 7.8E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 WM46_RS09145 53b81b63254267345350213ed6ab6c30 57 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 32 52 9.1E-10 T 28-03-2018 IPR019626 Stress-induced protein, KGG, repeat WM46_RS09145 53b81b63254267345350213ed6ab6c30 57 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 10 30 3.0E-10 T 28-03-2018 IPR019626 Stress-induced protein, KGG, repeat WM46_RS07540 7595467737c38bbea1baa00a5fd5f0f0 79 Pfam PF06945 Protein of unknown function (DUF1289) 12 57 4.8E-19 T 28-03-2018 IPR010710 Protein of unknown function DUF1289 WM46_RS22225 fd1acefb5ce482deaaf9e7bb049ffede 145 Pfam PF07419 PilM 13 144 6.7E-26 T 28-03-2018 IPR009987 PilM, inner membrane WM46_RS20315 29ecb0ec841274c84922fd2190b9e8eb 120 Pfam PF10928 Protein of unknown function (DUF2810) 66 117 4.9E-33 T 28-03-2018 IPR021230 Protein of unknown function DUF2810 WM46_RS03760 4d376ac5aa1b9766a2f619f025af0582 75 Pfam PF10733 Protein of unknown function (DUF2525) 18 75 2.0E-31 T 28-03-2018 IPR019669 Uncharacterised bacterial stress protein YodD WM46_RS06615 b0852ecb9f4e12362782e822f2c29f6d 77 Pfam PF10735 Protein of unknown function (DUF2526) 1 77 8.6E-45 T 28-03-2018 IPR019671 Protein of unknown function DUF2526 WM46_RS04480 0cb1a03e55097b2a376c66838e65c27a 160 Pfam PF05565 Siphovirus Gp157 4 160 9.7E-43 T 28-03-2018 IPR008840 Siphovirus Gp157 WM46_RS04860 c34faa62490d6b82c44f039d47f9bfd4 877 Pfam PF02470 MlaD protein 46 137 3.4E-17 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS04860 c34faa62490d6b82c44f039d47f9bfd4 877 Pfam PF02470 MlaD protein 747 809 6.9E-9 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS04860 c34faa62490d6b82c44f039d47f9bfd4 877 Pfam PF02470 MlaD protein 163 220 1.6E-6 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS04860 c34faa62490d6b82c44f039d47f9bfd4 877 Pfam PF02470 MlaD protein 394 455 9.6E-6 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS04860 c34faa62490d6b82c44f039d47f9bfd4 877 Pfam PF02470 MlaD protein 280 354 1.9E-8 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS04860 c34faa62490d6b82c44f039d47f9bfd4 877 Pfam PF02470 MlaD protein 636 724 4.3E-9 T 28-03-2018 IPR003399 Mce/MlaD WM46_RS10165 4224c06c2f33a72b968f8de78ccd54f6 158 Pfam PF10722 Putative bacterial sensory transduction regulator 8 131 8.9E-16 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN WM46_RS03365 e8465c0c57eec2a39ea212c4831eff31 380 Pfam PF04865 Baseplate J-like protein 67 344 2.3E-61 T 28-03-2018 IPR006949 Baseplate protein J-like WM46_RS03370 d2dc0450b12e20d501289c1fa20720d8 197 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 12 197 5.6E-41 T 28-03-2018 IPR018755 Bacteriophage Mu-like, Gp48 WM46_RS17745 eeac15ddbce95dd784ccf58ec306746e 58 Pfam PF13978 Protein of unknown function (DUF4223) 1 54 1.2E-33 T 28-03-2018 IPR025318 Protein of unknown function DUF4223 WM46_RS19350 a4c4ff7d036b31794f438746bc460e3d 32 Pfam PF08046 IlvGEDA operon leader peptide 1 32 1.5E-17 T 28-03-2018 IPR012567 IlvGEDA operon leader peptide GO:0009082 WM46_RS16120 f18d9377ba39d5b9de70799e05a5a778 140 Pfam PF06853 Protein of unknown function (DUF1249) 21 134 1.2E-41 T 28-03-2018 IPR009659 Protein of unknown function DUF1249 WM46_RS04405 cac1b0cf83c83c34c799b62906d44e9b 290 Pfam PF05425 Copper resistance protein D 186 283 1.0E-23 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 WM46_RS20480 bef543d3ca91c975a0c063f945b256bc 101 Pfam PF13983 YsaB-like lipoprotein 27 101 7.2E-45 T 28-03-2018 IPR025728 YsaB-like lipoprotein WM46_RS23975 32d8c12934d8148d030e552d21500ed9 258 Pfam PF06738 Putative threonine/serine exporter 13 252 2.7E-70 T 28-03-2018 IPR010619 Putative threonine/serine exporter WM46_RS23585 b11375b624caa6b6deb1c7467793fd68 112 Pfam PF11682 Probable zinc-ribbon 4 85 1.4E-10 T 28-03-2018 IPR021696 Protein of unknown function DUF3279 WM46_RS22335 c8abaa4ede9586ec7beb947855533556 89 Pfam PF04193 PQ loop repeat 7 59 2.7E-12 T 28-03-2018 IPR006603 PQ-loop repeat WM46_RS10105 5bfd436b3283c91be122c738789fd111 171 Pfam PF12883 Protein of unknown function (DUF3828) 40 154 3.7E-23 T 28-03-2018 IPR024289 Domain of unknown function DUF3828 WM46_RS21740 3ebdadb9e44bd73d8e7e6123c48c088a 136 Pfam PF03788 LrgA family 31 122 5.2E-25 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 WM46_RS26255 fbc2feb8a18afb8f02f838dd392f8b23 113 Pfam PF16509 TrfB plasmid transcriptional repressor 7 93 1.4E-20 T 28-03-2018 IPR032428 TrfB transcriptional repressor protein WM46_RS25780 4cfc238f1476d6d608dc5c2960bfc41a 118 Gene3D G3DSA:1.20.120.20 14 118 1.9E-4 T 28-03-2018 WM46_RS04035 a37b5ff88ea8ed3a778d55ee3acb7d84 111 Pfam PF13992 YecR-like lipoprotein 26 98 1.5E-27 T 28-03-2018 IPR025731 YecR-like lipoprotein WM46_RS13545 546e0aa58666a413220771df07754f2a 540 Pfam PF12236 Bacteriophage head to tail connecting protein 14 490 1.7E-157 T 28-03-2018 IPR020991 Head-to-tail connector protein, podovirus-type WM46_RS09255 c803d3c95a3067c0bfa04e55dbab8898 371 Pfam PF01594 AI-2E family transporter 11 339 1.4E-52 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like