locus-tag	class	description
C2U38_RS00005	COG0366	Alpha amylase catalytic
C2U38_RS00015	COG2992	FlgJ-related protein
C2U38_RS00020	COG2207	Transcriptional regulator
C2U38_RS00020	COG1609	Transcriptional regulator
C2U38_RS00025	COG4214	carbohydrate transport
C2U38_RS00035	COG4213	ABC transporter substrate-binding protein
C2U38_RS00045	COG1070	Carbohydrate kinase
C2U38_RS00050	COG4682	membrane
C2U38_RS00055	COG4682	membrane
C2U38_RS00060	COG3274	enterobacterial common antigen metabolic process
C2U38_RS00085	COG1278	Cold shock
C2U38_RS00090	COG2944	sequence-specific DNA binding
C2U38_RS00105	COG2814	Major facilitator Superfamily
C2U38_RS00110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS00120	COG1609	Transcriptional regulator
C2U38_RS00125	COG2885	chlorophyll binding
C2U38_RS00130	COG0243	molybdopterin cofactor binding
C2U38_RS00135	COG0456	acetyltransferase
C2U38_RS00140	COG2818	Glycosylase
C2U38_RS00145	COG5571	outer membrane autotransporter
C2U38_RS00150	COG2223	nitrite transmembrane transporter activity
C2U38_RS00175	COG0747	negative chemotaxis
C2U38_RS00180	COG0601	transmembrane transport
C2U38_RS00185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2U38_RS00190	COG0444	Belongs to the ABC transporter superfamily
C2U38_RS00195	COG4608	Belongs to the ABC transporter superfamily
C2U38_RS00200	COG2204	response regulator
C2U38_RS00205	COG0814	amino acid
C2U38_RS00210	COG0626	cystathionine gamma-synthase activity
C2U38_RS00220	COG2200	EAL domain
C2U38_RS00220	COG2199	diguanylate cyclase activity
C2U38_RS00245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS00250	COG2200	EAL domain
C2U38_RS00255	COG2982	Protein involved in outer membrane biogenesis
C2U38_RS00260	COG0477	Major facilitator Superfamily
C2U38_RS00265	COG1295	ribonuclease BN
C2U38_RS00270	COG0583	DNA-binding transcription factor activity
C2U38_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS00280	COG2197	response regulator
C2U38_RS00290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2U38_RS00305	COG1858	cytochrome C peroxidase
C2U38_RS00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2U38_RS00315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C2U38_RS00320	COG0339	signal peptide processing
C2U38_RS00330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS00330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS00335	COG0246	Mannitol dehydrogenase
C2U38_RS00340	COG1349	DNA-binding transcription factor activity
C2U38_RS00350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS00350	COG2213	PTS system mannitol-specific
C2U38_RS00365	COG1959	2 iron, 2 sulfur cluster binding
C2U38_RS00380	COG0589	response to stress
C2U38_RS00390	COG0306	phosphate transporter
C2U38_RS00395	COG2081	HI0933 family
C2U38_RS00415	COG5642	Protein of unknown function (DUF2384)
C2U38_RS00435	COG3621	Patatin-like phospholipase
C2U38_RS00480	COG2239	Acts as a magnesium transporter
C2U38_RS00485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2U38_RS00490	COG0842	Transport permease protein
C2U38_RS00490	COG1129	ABC transporter
C2U38_RS00495	COG0842	Transport permease protein
C2U38_RS00515	COG3479	Phenolic acid decarboxylase
C2U38_RS00520	COG2091	lysine biosynthetic process via aminoadipic acid
C2U38_RS00525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2U38_RS00530	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS00540	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2U38_RS00565	COG1216	Glycosyl transferase, family 2
C2U38_RS00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C2U38_RS00615	COG0628	permease
C2U38_RS00620	COG0477	Major facilitator Superfamily
C2U38_RS00630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C2U38_RS00645	COG3714	YhhN family
C2U38_RS00655	COG3776	membrane
C2U38_RS00660	COG0742	ribosomal rna small subunit methyltransferase
C2U38_RS00665	COG0552	protein localization to endoplasmic reticulum
C2U38_RS00670	COG2884	Cell division ATP-binding protein ftsE
C2U38_RS00675	COG2177	Part of the ABC transporter FtsEX involved in
C2U38_RS00695	COG0683	leucine binding
C2U38_RS00705	COG4177	L-phenylalanine transmembrane transporter activity
C2U38_RS00710	COG0411	ABC transporter
C2U38_RS00715	COG0410	ABC transporter
C2U38_RS00745	COG0584	glycerophosphoryl diester phosphodiesterase
C2U38_RS00755	COG0405	Gamma-glutamyltransferase
C2U38_RS00765	COG1247	-acetyltransferase
C2U38_RS00775	COG0673	inositol 2-dehydrogenase activity
C2U38_RS00780	COG1741	Belongs to the pirin family
C2U38_RS00785	COG1609	Transcriptional regulator
C2U38_RS00790	COG3265	gluconokinase activity
C2U38_RS00795	COG2610	gluconate transmembrane transporter activity
C2U38_RS00805	COG2095	MarC family integral membrane protein
C2U38_RS00810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2U38_RS00835	COG0058	SHG alpha-glucan phosphorylase activity
C2U38_RS00840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2U38_RS00855	COG1349	DNA-binding transcription factor activity
C2U38_RS00865	COG0058	SHG alpha-glucan phosphorylase activity
C2U38_RS00870	COG1640	4-alpha-glucanotransferase
C2U38_RS00875	COG2610	gluconate transmembrane transporter activity
C2U38_RS00885	COG1040	competence protein
C2U38_RS00895	COG5464	transposase or invertase
C2U38_RS00910	COG1918	ferrous iron import across plasma membrane
C2U38_RS00915	COG2183	response to ionizing radiation
C2U38_RS00920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2U38_RS00940	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C2U38_RS00950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C2U38_RS00955	COG1011	Hydrolase
C2U38_RS00965	COG0494	nUDIX hydrolase
C2U38_RS00970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C2U38_RS00975	COG4972	Pilus assembly protein
C2U38_RS00995	COG4796	Type ii and iii secretion system protein
C2U38_RS01015	COG3266	domain, Protein
C2U38_RS01020	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C2U38_RS01025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2U38_RS01035	COG0180	Tryptophanyl-tRNA synthetase
C2U38_RS01060	COG2146	nitrite reductase [NAD(P)H] activity
C2U38_RS01065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2U38_RS01090	COG0512	Glutamine amidotransferase of anthranilate synthase
C2U38_RS01095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2U38_RS01100	COG1289	transmembrane transporter activity
C2U38_RS01115	COG1765	OsmC-like protein
C2U38_RS01120	COG3954	Phosphoribulokinase
C2U38_RS01130	COG0429	hydrolase of the alpha beta-hydrolase fold
C2U38_RS01135	COG0488	(ABC) transporter
C2U38_RS01155	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C2U38_RS01160	COG1047	Peptidyl-prolyl cis-trans
C2U38_RS01170	COG0545	Peptidyl-prolyl cis-trans isomerase
C2U38_RS01175	COG2964	Protein conserved in bacteria
C2U38_RS01240	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C2U38_RS01245	COG3156	type II secretion system protein K
C2U38_RS01250	COG4795	General secretion pathway protein
C2U38_RS01255	COG2165	general secretion pathway protein
C2U38_RS01260	COG2165	general secretion pathway protein
C2U38_RS01265	COG2165	general secretion pathway protein
C2U38_RS01270	COG1459	type II secretion system
C2U38_RS01275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2U38_RS01280	COG1450	Type ii and iii secretion system protein
C2U38_RS01300	COG0051	transcription antitermination factor activity, RNA binding
C2U38_RS01310	COG0088	Forms part of the polypeptide exit tunnel
C2U38_RS01325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C2U38_RS01400	COG0200	Binds to the 23S rRNA
C2U38_RS01405	COG0201	protein transport
C2U38_RS01420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C2U38_RS01445	COG0789	Transcriptional regulator
C2U38_RS01450	COG3036	rescue of stalled ribosome
C2U38_RS01460	COG0569	domain protein
C2U38_RS01480	COG0758	DNA mediated transformation
C2U38_RS01490	COG0551	DNA topoisomerase type I activity
C2U38_RS01510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2U38_RS01595	COG3596	GTP binding
C2U38_RS01640	COG4974	Belongs to the 'phage' integrase family
C2U38_RS01665	COG3039	Transposase
C2U38_RS01705	COG1309	transcriptional regulator
C2U38_RS01720	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2U38_RS01725	COG1027	Aspartate ammonia-lyase
C2U38_RS01730	COG3030	protein affecting phage T7 exclusion by the F plasmid
C2U38_RS01735	COG0531	amino acid
C2U38_RS01765	COG1509	lysine 2,3-aminomutase activity
C2U38_RS01820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2U38_RS01825	COG1053	succinate dehydrogenase
C2U38_RS01850	COG3264	Mechanosensitive ion channel
C2U38_RS01850	COG1511	domain protein
C2U38_RS01885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C2U38_RS01890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C2U38_RS01890	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C2U38_RS01895	COG0802	atpase or kinase
C2U38_RS01900	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2U38_RS01915	COG1923	regulation of RNA biosynthetic process
C2U38_RS01920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C2U38_RS01925	COG0330	HflC and HflK could
C2U38_RS01930	COG0330	HflC and HflK could
C2U38_RS01935	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C2U38_RS01955	COG0557	exoribonuclease II activity
C2U38_RS01960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2U38_RS01965	COG1960	acyl-CoA dehydrogenase activity
C2U38_RS01975	COG3650	response to hydrogen peroxide
C2U38_RS01980	COG1073	alpha beta
C2U38_RS02030	COG0730	response to heat
C2U38_RS02045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C2U38_RS02060	COG3061	Opacity-associated protein A
C2U38_RS02065	COG0545	Peptidyl-prolyl cis-trans isomerase
C2U38_RS02070	COG1113	amino acid transport
C2U38_RS02080	COG0840	transmembrane signaling receptor activity
C2U38_RS02085	COG0697	spore germination
C2U38_RS02095	COG0702	epimerase
C2U38_RS02100	COG1733	regulation of RNA biosynthetic process
C2U38_RS02110	COG1218	3'(2'),5'-bisphosphate nucleotidase
C2U38_RS02115	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C2U38_RS02130	COG1253	flavin adenine dinucleotide binding
C2U38_RS02140	COG0729	surface antigen
C2U38_RS02145	COG2911	Protein conserved in bacteria
C2U38_RS02150	COG2105	PFAM AIG2 family protein
C2U38_RS02155	COG4771	TonB-dependent receptor
C2U38_RS02160	COG3391	amine dehydrogenase activity
C2U38_RS02170	COG1879	ABC-type sugar transport system periplasmic component
C2U38_RS02175	COG1129	ABC transporter
C2U38_RS02180	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS02185	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS02190	COG0840	transmembrane signaling receptor activity
C2U38_RS02200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C2U38_RS02205	COG0517	IMP dehydrogenase activity
C2U38_RS02205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2U38_RS02210	COG1486	melibiose metabolic process
C2U38_RS02220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2U38_RS02230	COG0312	modulator of DNA gyrase
C2U38_RS02265	COG3964	amidohydrolase
C2U38_RS02280	COG3711	transcriptional antiterminator
C2U38_RS02280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS02320	COG3039	Transposase
C2U38_RS02370	COG2026	Addiction module toxin, RelE StbE family
C2U38_RS02395	COG0366	Alpha amylase catalytic
C2U38_RS02400	COG1263	PTS System
C2U38_RS02400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS02450	COG1438	arginine binding
C2U38_RS02455	COG1288	antiporter activity
C2U38_RS02460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C2U38_RS02475	COG2731	YhcH YjgK YiaL family protein
C2U38_RS02510	COG0525	valine-tRNA ligase activity
C2U38_RS02515	COG2927	DNA polymerase III (CHI subunit)
C2U38_RS02530	COG0795	lipopolysaccharide-transporting ATPase activity
C2U38_RS02535	COG0795	lipopolysaccharide-transporting ATPase activity
C2U38_RS02540	COG0433	COG0433 Predicted ATPase
C2U38_RS02545	COG1609	Transcriptional regulator
C2U38_RS02550	COG2610	gluconate transmembrane transporter activity
C2U38_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS02560	COG1063	alcohol dehydrogenase
C2U38_RS02565	COG3265	gluconokinase activity
C2U38_RS02570	COG1064	alcohol dehydrogenase
C2U38_RS02580	COG0582	viral genome integration into host DNA
C2U38_RS02615	COG0514	ATP-dependent DNA helicase (RecQ)
C2U38_RS02640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C2U38_RS02645	COG0720	synthase
C2U38_RS02685	COG3596	GTP binding
C2U38_RS02695	COG2378	regulation of single-species biofilm formation
C2U38_RS02700	COG3468	outer membrane autotransporter barrel domain protein
C2U38_RS02715	COG2003	Belongs to the UPF0758 family
C2U38_RS02735	COG0582	viral genome integration into host DNA
C2U38_RS02740	COG1196	nuclear chromosome segregation
C2U38_RS02830	COG1620	l-lactate permease
C2U38_RS02835	COG0247	lactate metabolic process
C2U38_RS02840	COG1139	Iron-sulfur cluster binding protein
C2U38_RS02845	COG1556	Lactate utilization protein
C2U38_RS02850	COG2610	gluconate transmembrane transporter activity
C2U38_RS02860	COG0246	Mannitol dehydrogenase
C2U38_RS02865	COG2186	Transcriptional regulator
C2U38_RS02875	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2U38_RS02885	COG0477	Major facilitator Superfamily
C2U38_RS02890	COG2733	membrane
C2U38_RS02895	COG0583	DNA-binding transcription factor activity
C2U38_RS02900	COG1301	dicarboxylic acid transport
C2U38_RS02905	COG0626	cystathionine gamma-synthase activity
C2U38_RS02920	COG2207	Transcriptional regulator
C2U38_RS02920	COG1917	Cupin 2, conserved barrel domain protein
C2U38_RS02930	COG5464	transposase or invertase
C2U38_RS02930	COG5464	transposase or invertase
C2U38_RS02935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2U38_RS02940	COG5457	Domain of unknown function (DUF1127)
C2U38_RS02950	COG1566	PFAM secretion protein HlyD family protein
C2U38_RS02980	COG1715	Restriction endonuclease
C2U38_RS03010	COG3039	Transposase
C2U38_RS03025	COG0523	cobalamin synthesis protein
C2U38_RS03030	COG2879	small protein
C2U38_RS03035	COG1966	Carbon starvation protein
C2U38_RS03040	COG0840	transmembrane signaling receptor activity
C2U38_RS03050	COG2271	Major facilitator Superfamily
C2U38_RS03055	COG1802	Transcriptional regulator
C2U38_RS03060	COG1063	alcohol dehydrogenase
C2U38_RS03080	COG1484	DNA-dependent DNA replication
C2U38_RS03095	COG2966	Psort location CytoplasmicMembrane, score
C2U38_RS03100	COG2197	response regulator
C2U38_RS03105	COG2197	response regulator
C2U38_RS03110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2U38_RS03115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2U38_RS03120	COG4114	ferric iron reductase
C2U38_RS03125	COG3706	GGDEF domain
C2U38_RS03155	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
C2U38_RS03160	COG0456	acetyltransferase
C2U38_RS03165	COG1011	Hydrolase
C2U38_RS03175	COG2823	Periplasmic or secreted lipoprotein
C2U38_RS03180	COG5487	UPF0391 membrane protein
C2U38_RS03185	COG4667	esterase of the alpha-beta hydrolase superfamily
C2U38_RS03190	COG0084	hydrolase, TatD family'
C2U38_RS03195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2U38_RS03200	COG1328	CTP reductase activity
C2U38_RS03230	COG3726	membrane protein affecting hemolysin expression
C2U38_RS03240	COG0560	Phosphoserine phosphatase
C2U38_RS03255	COG0488	(ABC) transporter
C2U38_RS03260	COG0741	lytic transglycosylase activity
C2U38_RS03280	COG3708	Transcriptional regulator
C2U38_RS03280	COG2207	Transcriptional regulator
C2U38_RS03285	COG3045	CreA protein
C2U38_RS03290	COG0745	RESPONSE REGULATOR receiver
C2U38_RS03295	COG2205	protein histidine kinase activity
C2U38_RS03300	COG4452	Inner membrane protein CreD
C2U38_RS03305	COG0745	RESPONSE REGULATOR receiver
C2U38_RS03320	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C2U38_RS03330	COG0527	aspartate kinase activity
C2U38_RS03330	COG0460	homoserine dehydrogenase
C2U38_RS03340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2U38_RS03350	COG1115	amino acid carrier protein
C2U38_RS03360	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2U38_RS03370	COG1584	GPR1 FUN34 yaaH family protein
C2U38_RS03375	COG0443	Heat shock 70 kDa protein
C2U38_RS03390	COG0583	DNA-binding transcription factor activity
C2U38_RS03410	COG0196	riboflavin kinase activity
C2U38_RS03425	COG1047	Peptidyl-prolyl cis-trans
C2U38_RS03440	COG2140	Oxalate decarboxylase
C2U38_RS03450	COG3716	PTS system mannose fructose sorbose family IID component
C2U38_RS03455	COG3715	PTS system
C2U38_RS03460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS03460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS03475	COG1609	Transcriptional regulator
C2U38_RS03485	COG0505	Belongs to the CarA family
C2U38_RS03490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C2U38_RS03545	COG0644	oxidoreductase
C2U38_RS03555	COG2271	Major facilitator Superfamily
C2U38_RS03620	COG0564	pseudouridine synthase activity
C2U38_RS03630	COG0417	DNA replication proofreading
C2U38_RS03645	COG0235	Class ii aldolase
C2U38_RS03665	COG0586	Pfam SNARE associated Golgi protein
C2U38_RS03675	COG1178	ABC-type Fe3 transport system permease component
C2U38_RS03695	COG2814	Major facilitator Superfamily
C2U38_RS03730	COG0028	Belongs to the TPP enzyme family
C2U38_RS03765	COG0768	penicillin binding
C2U38_RS03770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C2U38_RS03775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C2U38_RS03785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C2U38_RS03790	COG0772	Belongs to the SEDS family
C2U38_RS03805	COG1181	Belongs to the D-alanine--D-alanine ligase family
C2U38_RS03815	COG0849	cell division
C2U38_RS03820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C2U38_RS03840	COG0494	nUDIX hydrolase
C2U38_RS03855	COG0237	dephospho-CoA kinase activity
C2U38_RS03865	COG1459	type II secretion system
C2U38_RS03870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2U38_RS03875	COG4969	Belongs to the N-Me-Phe pilin family
C2U38_RS03890	COG3725	Membrane protein required for beta-lactamase induction
C2U38_RS03895	COG3940	Belongs to the glycosyl hydrolase 43 family
C2U38_RS03900	COG2211	Major facilitator Superfamily
C2U38_RS03915	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C2U38_RS03920	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2U38_RS03925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2U38_RS03940	COG3064	Membrane
C2U38_RS03990	COG4993	Dehydrogenase
C2U38_RS03995	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C2U38_RS04000	COG0288	reversible hydration of carbon dioxide
C2U38_RS04005	COG1131	(ABC) transporter
C2U38_RS04010	COG0842	Transport permease protein
C2U38_RS04015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS04020	COG0726	polysaccharide deacetylase
C2U38_RS04040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2U38_RS04045	COG0617	tRNA 3'-terminal CCA addition
C2U38_RS04065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2U38_RS04070	COG1643	Atp-dependent helicase
C2U38_RS04075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2U38_RS04080	COG4774	siderophore transport
C2U38_RS04085	COG1120	ATPase activity
C2U38_RS04090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2U38_RS04115	COG2860	membrane
C2U38_RS04145	COG3835	regulator
C2U38_RS04190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C2U38_RS04200	COG0575	Belongs to the CDS family
C2U38_RS04215	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C2U38_RS04220	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C2U38_RS04255	COG1982	Orn Lys Arg decarboxylase major
C2U38_RS04260	COG0346	lactoylglutathione lyase activity
C2U38_RS04270	COG4568	rho-dependent transcription termination
C2U38_RS04285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C2U38_RS04290	COG3015	lipoprotein NlpE involved in copper resistance
C2U38_RS04295	COG0791	NLP P60 protein
C2U38_RS04305	COG1720	tRNA m6t6A37 methyltransferase activity
C2U38_RS04315	COG1464	Belongs to the NlpA lipoprotein family
C2U38_RS04320	COG2011	ABC-type metal ion transport system permease component
C2U38_RS04330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C2U38_RS04370	COG0583	DNA-binding transcription factor activity
C2U38_RS04375	COG2814	Major facilitator Superfamily
C2U38_RS04385	COG2226	methyltransferase
C2U38_RS04390	COG0741	lytic transglycosylase activity
C2U38_RS04390	COG1388	LysM domain
C2U38_RS04400	COG2226	methyltransferase
C2U38_RS04410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2U38_RS04430	COG3539	Fimbrial protein
C2U38_RS04440	COG3188	usher protein
C2U38_RS04445	COG3121	Chaperone
C2U38_RS04450	COG3539	Fimbrial protein
C2U38_RS04455	COG3539	Fimbrial protein
C2U38_RS04470	COG2200	EAL domain
C2U38_RS04480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2U38_RS04485	COG1960	acyl-CoA dehydrogenase activity
C2U38_RS04500	COG0121	glutamine amidotransferase
C2U38_RS04505	COG3034	peptidoglycan biosynthetic process
C2U38_RS04510	COG0791	NLP P60 protein
C2U38_RS04525	COG1684	flagellar biosynthetic protein fliR
C2U38_RS04530	COG1987	bacterial-type flagellum assembly
C2U38_RS04555	COG1677	Flagellar hook-basal body complex protein FliE
C2U38_RS04565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2U38_RS04585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C2U38_RS04590	COG0110	maltose O-acetyltransferase activity
C2U38_RS04605	COG0463	Glycosyl transferase, family 2
C2U38_RS04605	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C2U38_RS04640	COG1558	bacterial-type flagellum-dependent cell motility
C2U38_RS04655	COG4787	bacterial-type flagellum-dependent cell motility
C2U38_RS04660	COG4786	Flagellar basal body rod
C2U38_RS04680	COG1256	bacterial-type flagellum assembly
C2U38_RS04680	COG4786	Flagellar basal body rod
C2U38_RS04685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C2U38_RS04710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C2U38_RS04735	COG1191	sigma factor activity
C2U38_RS04740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C2U38_RS04760	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2U38_RS04785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C2U38_RS04795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2U38_RS04835	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2U38_RS04870	COG2003	Belongs to the UPF0758 family
C2U38_RS04890	COG2378	regulation of single-species biofilm formation
C2U38_RS04900	COG2378	regulation of single-species biofilm formation
C2U38_RS04910	COG3596	GTP binding
C2U38_RS04945	COG1294	oxidase, subunit
C2U38_RS04960	COG3206	protein involved in exopolysaccharide biosynthesis
C2U38_RS04960	COG0489	protein tyrosine kinase activity
C2U38_RS05005	COG0840	transmembrane signaling receptor activity
C2U38_RS05015	COG2963	transposase activity
C2U38_RS05020	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS05035	COG3344	reverse transcriptase
C2U38_RS05075	COG3039	Transposase
C2U38_RS05085	COG0582	viral genome integration into host DNA
C2U38_RS05100	COG1294	oxidase, subunit
C2U38_RS05105	COG1271	oxidase subunit
C2U38_RS05110	COG1773	rubredoxin
C2U38_RS05115	COG1999	signal sequence binding
C2U38_RS05120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2U38_RS05125	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
C2U38_RS05140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2U38_RS05145	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS05150	COG1917	Cupin 2, conserved barrel domain protein
C2U38_RS05150	COG1396	sequence-specific DNA binding
C2U38_RS05155	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C2U38_RS05160	COG0174	glutamine synthetase
C2U38_RS05165	COG0531	amino acid
C2U38_RS05170	COG0693	protein deglycase activity
C2U38_RS05175	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C2U38_RS05195	COG3210	domain, Protein
C2U38_RS05235	COG1414	Transcriptional regulator
C2U38_RS05270	COG2814	Major facilitator Superfamily
C2U38_RS05275	COG0833	amino acid
C2U38_RS05280	COG2040	homocysteine
C2U38_RS05285	COG3842	ATPase activity
C2U38_RS05295	COG1840	ABC-type Fe3 transport system, periplasmic component
C2U38_RS05300	COG2271	Major facilitator Superfamily
C2U38_RS05315	COG4521	taurine ABC transporter
C2U38_RS05320	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C2U38_RS05325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2U38_RS05330	COG2175	clavaminate synthase activity
C2U38_RS05335	COG0113	porphobilinogen synthase activity
C2U38_RS05345	COG3468	outer membrane autotransporter barrel domain protein
C2U38_RS05350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2U38_RS05355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2U38_RS05360	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C2U38_RS05380	COG1181	Belongs to the D-alanine--D-alanine ligase family
C2U38_RS05395	COG1785	Belongs to the alkaline phosphatase family
C2U38_RS05405	COG3706	GGDEF domain
C2U38_RS05410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2U38_RS05430	COG4126	flavin adenine dinucleotide binding
C2U38_RS05445	COG1940	carbohydrate kinase activity
C2U38_RS05450	COG2814	Major facilitator Superfamily
C2U38_RS05455	COG0419	ATPase involved in DNA repair
C2U38_RS05460	COG0420	3'-5' exonuclease activity
C2U38_RS05470	COG5002	protein histidine kinase activity
C2U38_RS05490	COG0366	Alpha amylase catalytic
C2U38_RS05495	COG0583	DNA-binding transcription factor activity
C2U38_RS05500	COG1335	isochorismatase
C2U38_RS05510	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C2U38_RS05525	COG0450	alkyl hydroperoxide reductase
C2U38_RS05535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C2U38_RS05545	COG1862	Preprotein translocase
C2U38_RS05550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2U38_RS05555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2U38_RS05575	COG4238	major outer membrane lipoprotein
C2U38_RS05585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2U38_RS05585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2U38_RS05600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C2U38_RS05605	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C2U38_RS05610	COG0667	Aldo Keto reductase
C2U38_RS05620	COG0142	geranyltranstransferase activity
C2U38_RS05655	COG2814	Major facilitator Superfamily
C2U38_RS05680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C2U38_RS05685	COG1845	cytochrome c oxidase, subunit III
C2U38_RS05690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C2U38_RS05695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C2U38_RS05700	COG2223	nitrite transmembrane transporter activity
C2U38_RS05705	COG3056	Lipoprotein
C2U38_RS05710	COG0271	Belongs to the BolA IbaG family
C2U38_RS05730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C2U38_RS05735	COG0776	regulation of translation
C2U38_RS05740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2U38_RS05790	COG4974	Belongs to the 'phage' integrase family
C2U38_RS05795	COG1555	photosystem II stabilization
C2U38_RS05800	COG0824	Thioesterase
C2U38_RS05810	COG4533	DNA binding
C2U38_RS05825	COG1522	sequence-specific DNA binding
C2U38_RS05830	COG1132	(ABC) transporter
C2U38_RS05835	COG1132	(ABC) transporter
C2U38_RS05845	COG0347	Belongs to the P(II) protein family
C2U38_RS05850	COG0004	ammonium transporteR
C2U38_RS05855	COG1946	Acyl-CoA thioesterase
C2U38_RS05860	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C2U38_RS05865	COG3695	enzyme binding
C2U38_RS05885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2U38_RS05890	COG2364	Membrane
C2U38_RS05895	COG5507	3-demethylubiquinone-9 3-methyltransferase
C2U38_RS05900	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2U38_RS05920	COG0110	maltose O-acetyltransferase activity
C2U38_RS05935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2U38_RS05940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2U38_RS05945	COG1309	transcriptional regulator
C2U38_RS05950	COG1196	nuclear chromosome segregation
C2U38_RS05950	COG3264	Mechanosensitive ion channel
C2U38_RS05960	COG3923	Primosomal replication protein n
C2U38_RS05965	COG2832	Protein of unknown function (DUF454)
C2U38_RS06020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS06025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C2U38_RS06025	COG4651	solute:proton antiporter activity
C2U38_RS06030	COG2223	nitrite transmembrane transporter activity
C2U38_RS06040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2U38_RS06045	COG3735	TraB family
C2U38_RS06060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS06070	COG3721	Heme iron utilization protein
C2U38_RS06080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2U38_RS06085	COG4771	TonB-dependent receptor
C2U38_RS06105	COG1585	Membrane protein implicated in regulation of membrane protease activity
C2U38_RS06110	COG0330	HflC and HflK could
C2U38_RS06115	COG4619	ABC transporter
C2U38_RS06120	COG0390	transport system, permease component
C2U38_RS06125	COG3118	belongs to the thioredoxin family
C2U38_RS06130	COG0300	oxidoreductase activity
C2U38_RS06135	COG2755	lipolytic protein G-D-S-L family
C2U38_RS06140	COG4181	ATPase activity
C2U38_RS06145	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C2U38_RS06155	COG1464	Belongs to the NlpA lipoprotein family
C2U38_RS06165	COG2011	ABC-type metal ion transport system permease component
C2U38_RS06175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C2U38_RS06180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C2U38_RS06195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2U38_RS06205	COG1988	membrane-bound metal-dependent
C2U38_RS06210	COG2501	S4 domain
C2U38_RS06285	COG0582	viral genome integration into host DNA
C2U38_RS06350	COG0842	Transport permease protein
C2U38_RS06355	COG0842	Transport permease protein
C2U38_RS06355	COG1129	ABC transporter
C2U38_RS06360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2U38_RS06410	COG3539	Fimbrial protein
C2U38_RS06470	COG3311	Transcriptional regulator
C2U38_RS06480	COG4983	Phage plasmid primase, P4 family domain protein
C2U38_RS06505	COG2003	Belongs to the UPF0758 family
C2U38_RS06565	COG2003	Belongs to the UPF0758 family
C2U38_RS06595	COG3596	GTP binding
C2U38_RS06600	COG0210	DNA helicase
C2U38_RS06625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C2U38_RS06650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS06670	COG0582	viral genome integration into host DNA
C2U38_RS06675	COG2801	Transposase and inactivated derivatives
C2U38_RS06690	COG0784	Response regulator, receiver
C2U38_RS06690	COG2205	protein histidine kinase activity
C2U38_RS06690	COG2198	Histidine kinase
C2U38_RS06700	COG3039	Transposase
C2U38_RS06710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2U38_RS06715	COG2207	Transcriptional regulator
C2U38_RS06740	COG1113	amino acid transport
C2U38_RS06745	COG2211	Major facilitator Superfamily
C2U38_RS06765	COG0668	transmembrane transport
C2U38_RS06775	COG2315	Protein conserved in bacteria
C2U38_RS06810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C2U38_RS06820	COG3958	Transketolase
C2U38_RS06825	COG3959	Transketolase, thiamine diphosphate binding domain
C2U38_RS06830	COG2390	Transcriptional regulator
C2U38_RS06835	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS06840	COG1129	ABC transporter
C2U38_RS06850	COG1879	ABC-type sugar transport system periplasmic component
C2U38_RS06860	COG4771	TonB-dependent receptor
C2U38_RS06865	COG2382	esterase
C2U38_RS06870	COG3251	PFAM MbtH domain protein
C2U38_RS06875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C2U38_RS06875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2U38_RS06880	COG1120	ATPase activity
C2U38_RS06885	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS06890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS06900	COG4592	Periplasmic binding protein
C2U38_RS06905	COG1169	isochorismate synthase
C2U38_RS06910	COG1021	2,3-dihydroxybenzoate-AMP ligase
C2U38_RS06915	COG3433	isochorismatase activity
C2U38_RS06915	COG1535	isochorismatase
C2U38_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS06930	COG1966	Carbon starvation protein
C2U38_RS06935	COG2879	small protein
C2U38_RS06940	COG0371	Dehydrogenase
C2U38_RS06945	COG0436	Aminotransferase
C2U38_RS06950	COG1475	DNA binding
C2U38_RS06955	COG3969	phosphoadenosine phosphosulfate
C2U38_RS06960	COG0583	DNA-binding transcription factor activity
C2U38_RS06965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2U38_RS06975	COG3634	alkyl hydroperoxide reductase activity
C2U38_RS07015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2U38_RS07030	COG3719	Belongs to the RNase T2 family
C2U38_RS07035	COG0471	metal ion transport
C2U38_RS07050	COG3051	citrate lyase alpha subunit
C2U38_RS07055	COG2301	Belongs to the HpcH HpaI aldolase family
C2U38_RS07065	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C2U38_RS07070	COG3290	protein histidine kinase activity
C2U38_RS07075	COG4565	transcriptional regulatory protein
C2U38_RS07080	COG3069	C4-dicarboxylate transmembrane transporter activity
C2U38_RS07085	COG3039	Transposase
C2U38_RS07105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2U38_RS07130	COG1686	Belongs to the peptidase S11 family
C2U38_RS07135	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2U38_RS07140	COG0772	Belongs to the SEDS family
C2U38_RS07145	COG0768	penicillin binding
C2U38_RS07155	COG0799	negative regulation of ribosome biogenesis
C2U38_RS07175	COG1466	dna polymerase III delta subunit
C2U38_RS07190	COG2888	peptidyl-tyrosine sulfation
C2U38_RS07210	COG3039	Transposase
C2U38_RS07225	COG1126	abc transporter atp-binding protein
C2U38_RS07230	COG0765	amino acid transport
C2U38_RS07235	COG0765	amino acid transport
C2U38_RS07255	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C2U38_RS07260	COG1702	phosphate starvation-inducible protein PhoH
C2U38_RS07270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2U38_RS07310	COG0367	asparagine synthase
C2U38_RS07320	COG0647	UMP catabolic process
C2U38_RS07330	COG1940	carbohydrate kinase activity
C2U38_RS07330	COG1846	Transcriptional regulator
C2U38_RS07335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2U38_RS07345	COG2190	(PTS) system
C2U38_RS07345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS07345	COG1263	PTS System
C2U38_RS07355	COG1653	transport
C2U38_RS07365	COG1609	Transcriptional regulator
C2U38_RS07390	COG1053	succinate dehydrogenase
C2U38_RS07395	COG0583	DNA-binding transcription factor activity
C2U38_RS07400	COG0735	belongs to the Fur family
C2U38_RS07410	COG0716	FMN binding
C2U38_RS07420	COG0596	Alpha beta hydrolase
C2U38_RS07425	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C2U38_RS07430	COG0033	Phosphoglucomutase
C2U38_RS07435	COG0531	amino acid
C2U38_RS07440	COG1982	Orn Lys Arg decarboxylase major
C2U38_RS07450	COG0745	RESPONSE REGULATOR receiver
C2U38_RS07455	COG2205	protein histidine kinase activity
C2U38_RS07490	COG5464	transposase or invertase
C2U38_RS07505	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C2U38_RS07510	COG1984	allophanate hydrolase subunit 2
C2U38_RS07540	COG3180	Ammonia monooxygenase
C2U38_RS07555	COG2009	succinate dehydrogenase
C2U38_RS07560	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C2U38_RS07565	COG1053	succinate dehydrogenase
C2U38_RS07570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2U38_RS07575	COG0567	Dehydrogenase, E1 component
C2U38_RS07580	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2U38_RS07590	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2U38_RS07610	COG3246	L-lysine catabolic process to acetate
C2U38_RS07615	COG3622	Belongs to the hyi family
C2U38_RS07620	COG1349	DNA-binding transcription factor activity
C2U38_RS07625	COG0235	Class ii aldolase
C2U38_RS07630	COG3395	kinase activity
C2U38_RS07655	COG1648	precorrin-2 dehydrogenase activity
C2U38_RS07655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C2U38_RS07660	COG0583	DNA-binding transcription factor activity
C2U38_RS07670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS07670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS07680	COG1301	dicarboxylic acid transport
C2U38_RS07695	COG3799	methylaspartate ammonia-lyase activity
C2U38_RS07700	COG4865	methylaspartate mutase activity
C2U38_RS07710	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C2U38_RS07715	COG1271	oxidase subunit
C2U38_RS07720	COG1294	oxidase, subunit
C2U38_RS07725	COG4890	Cyd operon protein YbgT
C2U38_RS07730	COG3790	cyd operon protein YbgE
C2U38_RS07740	COG0824	Thioesterase
C2U38_RS07745	COG0811	peptide transport
C2U38_RS07750	COG0848	biopolymer transport protein
C2U38_RS07755	COG3064	Membrane
C2U38_RS07765	COG2885	chlorophyll binding
C2U38_RS07770	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C2U38_RS07805	COG3201	nicotinamide mononucleotide transporter
C2U38_RS07810	COG1230	cation diffusion facilitator family transporter
C2U38_RS07820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2U38_RS07835	COG2017	converts alpha-aldose to the beta-anomer
C2U38_RS07845	COG1085	galactose-1-phosphate uridylyltransferase
C2U38_RS07850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C2U38_RS07855	COG1119	ATPase activity
C2U38_RS07860	COG2005	Transcriptional regulator
C2U38_RS07860	COG3585	molybdate ion transport
C2U38_RS07875	COG0725	ABC transporter, periplasmic molybdate-binding protein
C2U38_RS07880	COG4149	molybdate abc transporter
C2U38_RS07890	COG0561	phosphatase activity
C2U38_RS07905	COG0741	lytic transglycosylase activity
C2U38_RS07905	COG0739	heme binding
C2U38_RS07905	COG1196	nuclear chromosome segregation
C2U38_RS07915	COG1459	type II secretion system
C2U38_RS07920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2U38_RS07940	COG4796	Type ii and iii secretion system protein
C2U38_RS07955	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS07970	COG4677	pectinesterase activity
C2U38_RS08000	COG1881	PFAM PEBP family protein
C2U38_RS08040	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C2U38_RS08060	COG0626	cystathionine gamma-synthase activity
C2U38_RS08065	COG1757	Na H antiporter
C2U38_RS08085	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2U38_RS08095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C2U38_RS08100	COG0314	molybdopterin synthase activity
C2U38_RS08105	COG0670	Belongs to the BI1 family
C2U38_RS08110	COG0392	lysyltransferase activity
C2U38_RS08115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2U38_RS08120	COG3568	Endonuclease Exonuclease Phosphatase
C2U38_RS08130	COG0842	Transport permease protein
C2U38_RS08135	COG0842	Transport permease protein
C2U38_RS08140	COG1131	(ABC) transporter
C2U38_RS08150	COG1309	transcriptional regulator
C2U38_RS08155	COG0513	Belongs to the DEAD box helicase family
C2U38_RS08165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2U38_RS08170	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C2U38_RS08180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2U38_RS08190	COG4774	siderophore transport
C2U38_RS08205	COG0668	transmembrane transport
C2U38_RS08210	COG1126	abc transporter atp-binding protein
C2U38_RS08215	COG0765	amino acid transport
C2U38_RS08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS08235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C2U38_RS08240	COG2194	sulfuric ester hydrolase activity
C2U38_RS08255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2U38_RS08260	COG1376	ErfK ybiS ycfS ynhG family protein
C2U38_RS08265	COG0488	(ABC) transporter
C2U38_RS08275	COG0561	phosphatase activity
C2U38_RS08280	COG1882	Formate acetyltransferase
C2U38_RS08285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2U38_RS08290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2U38_RS08295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2U38_RS08300	COG0303	'Molybdopterin
C2U38_RS08315	COG1446	asparaginase
C2U38_RS08350	COG2133	pyrroloquinoline quinone binding
C2U38_RS08355	COG0625	glutathione transferase activity
C2U38_RS08360	COG1686	Belongs to the peptidase S11 family
C2U38_RS08365	COG1349	DNA-binding transcription factor activity
C2U38_RS08370	COG0671	phosphoesterase, PA-phosphatase related
C2U38_RS08375	COG2814	Major facilitator Superfamily
C2U38_RS08385	COG0561	phosphatase activity
C2U38_RS08390	COG0738	Major facilitator superfamily
C2U38_RS08395	COG3226	Transcriptional regulator
C2U38_RS08440	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2U38_RS08445	COG3842	ATPase activity
C2U38_RS08450	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2U38_RS08455	COG1177	transmembrane transport
C2U38_RS08465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C2U38_RS08480	COG1335	isochorismatase
C2U38_RS08490	COG0583	DNA-binding transcription factor activity
C2U38_RS08495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C2U38_RS08510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C2U38_RS08515	COG4988	ABC transporter
C2U38_RS08520	COG0492	ferredoxin-NADP+ reductase activity
C2U38_RS08535	COG1178	ABC-type Fe3 transport system permease component
C2U38_RS08535	COG1674	ftsk spoiiie
C2U38_RS08545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C2U38_RS08555	COG0243	molybdopterin cofactor binding
C2U38_RS08560	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS08565	COG3302	dmso reductase anchor subunit
C2U38_RS08570	COG1335	isochorismatase
C2U38_RS08580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS08585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C2U38_RS08590	COG3959	Transketolase, thiamine diphosphate binding domain
C2U38_RS08610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2U38_RS08615	COG1882	Formate acetyltransferase
C2U38_RS08620	COG2116	formate transmembrane transporter activity
C2U38_RS08625	COG1944	ATP diphosphatase activity
C2U38_RS08630	COG2323	membrane
C2U38_RS08655	COG0539	negative regulation of cytoplasmic translation
C2U38_RS08660	COG0776	regulation of translation
C2U38_RS08665	COG2333	competence protein COMEC
C2U38_RS08665	COG0658	competence protein
C2U38_RS08680	COG3214	Protein conserved in bacteria
C2U38_RS08695	COG3173	Aminoglycoside phosphotransferase
C2U38_RS08700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C2U38_RS08705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C2U38_RS08715	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C2U38_RS08725	COG2989	Protein conserved in bacteria
C2U38_RS08735	COG3108	Peptidase M15
C2U38_RS08740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2U38_RS08745	COG1448	Aminotransferase
C2U38_RS08765	COG0308	aminopeptidase N
C2U38_RS08775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2U38_RS08785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2U38_RS08790	COG0431	NADPH-dependent FMN reductase
C2U38_RS08810	COG0633	Ferredoxin
C2U38_RS08810	COG3217	Mosc domain protein beta barrel domain protein
C2U38_RS08820	COG0488	(ABC) transporter
C2U38_RS08825	COG2995	paraquat-inducible protein a
C2U38_RS08830	COG3008	intermembrane lipid transfer
C2U38_RS08830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C2U38_RS08835	COG3009	Protein conserved in bacteria
C2U38_RS08840	COG3130	regulation of translation
C2U38_RS08850	COG1067	ATP-dependent peptidase activity
C2U38_RS08870	COG3070	regulator of competence-specific genes
C2U38_RS08875	COG1289	transmembrane transporter activity
C2U38_RS08880	COG3304	Inner membrane component domain
C2U38_RS08885	COG0210	DNA helicase
C2U38_RS08900	COG1832	CoA-binding protein
C2U38_RS08925	COG2920	part of a sulfur-relay system
C2U38_RS08965	COG0670	Belongs to the BI1 family
C2U38_RS08970	COG4166	transmembrane transport
C2U38_RS08985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C2U38_RS08985	COG2857	Cytochrome c1
C2U38_RS09000	COG1120	ATPase activity
C2U38_RS09005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS09030	COG0813	purine-nucleoside phosphorylase activity
C2U38_RS09080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C2U38_RS09080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C2U38_RS09085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2U38_RS09095	COG0640	Transcriptional regulator
C2U38_RS09115	COG3729	General stress protein
C2U38_RS09125	COG1309	transcriptional regulator
C2U38_RS09130	COG3755	Protein conserved in bacteria
C2U38_RS09135	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2U38_RS09135	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2U38_RS09135	COG0506	proline dehydrogenase activity
C2U38_RS09145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2U38_RS09165	COG1702	phosphate starvation-inducible protein PhoH
C2U38_RS09190	COG3381	protein complex oligomerization
C2U38_RS09245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2U38_RS09270	COG5645	(Lipo)protein
C2U38_RS09285	COG1560	Kdo2-lipid A biosynthetic process
C2U38_RS09300	COG3038	cytochrome b561
C2U38_RS09340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2U38_RS09380	COG1558	bacterial-type flagellum-dependent cell motility
C2U38_RS09395	COG4787	bacterial-type flagellum-dependent cell motility
C2U38_RS09400	COG4786	Flagellar basal body rod
C2U38_RS09430	COG1530	ribonuclease E activity
C2U38_RS09445	COG0564	pseudouridine synthase activity
C2U38_RS09455	COG1399	metal-binding, possibly nucleic acid-binding protein
C2U38_RS09490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2U38_RS09495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2U38_RS09500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C2U38_RS09510	COG0470	DNA polymerase III
C2U38_RS09515	COG0084	hydrolase, TatD family'
C2U38_RS09525	COG0006	proline dipeptidase activity
C2U38_RS09530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C2U38_RS09535	COG0477	Major facilitator Superfamily
C2U38_RS09550	COG0583	DNA-binding transcription factor activity
C2U38_RS09570	COG3039	Transposase
C2U38_RS09595	COG3423	Transcriptional regulator
C2U38_RS09620	COG0582	viral genome integration into host DNA
C2U38_RS09630	COG0534	Mate efflux family protein
C2U38_RS09640	COG4773	Receptor
C2U38_RS09645	COG0537	adenosine 5'-monophosphoramidase activity
C2U38_RS09650	COG5633	Lipoprotein
C2U38_RS09675	COG1252	NADH dehydrogenase
C2U38_RS09680	COG3134	Outer membrane lipoprotein
C2U38_RS09690	COG1309	transcriptional regulator
C2U38_RS09700	COG1376	ErfK ybiS ycfS ynhG family protein
C2U38_RS09700	COG1388	LysM domain
C2U38_RS09705	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C2U38_RS09710	COG4763	Acyl-transferase
C2U38_RS09715	COG4591	ABC-type transport system involved in lipoprotein release permease component
C2U38_RS09720	COG1136	(ABC) transporter
C2U38_RS09725	COG4591	ABC-type transport system involved in lipoprotein release permease component
C2U38_RS09735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C2U38_RS09745	COG1177	transmembrane transport
C2U38_RS09760	COG1278	Cold shock
C2U38_RS09775	COG1289	transmembrane transporter activity
C2U38_RS09805	COG0431	NADPH-dependent FMN reductase
C2U38_RS09810	COG0640	Transcriptional regulator
C2U38_RS09845	COG1305	Transglutaminase-like
C2U38_RS09855	COG2608	mercury ion transmembrane transporter activity
C2U38_RS09860	COG3318	Belongs to the UPF0149 family
C2U38_RS09860	COG3012	SEC-C Motif Domain Protein
C2U38_RS09865	COG0814	amino acid
C2U38_RS09875	COG1528	Iron-storage protein
C2U38_RS09890	COG0477	Major facilitator Superfamily
C2U38_RS09900	COG1528	Iron-storage protein
C2U38_RS09915	COG1879	ABC-type sugar transport system periplasmic component
C2U38_RS09920	COG1129	ABC transporter
C2U38_RS09925	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS09975	COG0835	chemotaxis
C2U38_RS09980	COG1301	dicarboxylic acid transport
C2U38_RS09990	COG0840	transmembrane signaling receptor activity
C2U38_RS10005	COG0745	RESPONSE REGULATOR receiver
C2U38_RS10015	COG4977	sequence-specific DNA binding
C2U38_RS10020	COG2814	Major facilitator Superfamily
C2U38_RS10025	COG3250	beta-galactosidase activity
C2U38_RS10050	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2U38_RS10065	COG3102	Protein conserved in bacteria
C2U38_RS10085	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C2U38_RS10090	COG1801	Protein of unknown function DUF72
C2U38_RS10095	COG1335	isochorismatase
C2U38_RS10110	COG0494	nUDIX hydrolase
C2U38_RS10130	COG2255	four-way junction helicase activity
C2U38_RS10135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C2U38_RS10155	COG1187	pseudouridine synthase activity
C2U38_RS10165	COG0538	isocitrate dehydrogenase activity
C2U38_RS10170	COG2814	Major facilitator Superfamily
C2U38_RS10175	COG1414	Transcriptional regulator
C2U38_RS10210	COG0768	penicillin binding
C2U38_RS10215	COG2226	methyltransferase
C2U38_RS10230	COG3716	PTS system mannose fructose sorbose family IID component
C2U38_RS10235	COG3715	PTS system
C2U38_RS10240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS10240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS10250	COG1253	flavin adenine dinucleotide binding
C2U38_RS10255	COG2200	EAL domain
C2U38_RS10260	COG1760	l-serine dehydratase
C2U38_RS10280	COG0251	oxidation-reduction process
C2U38_RS10285	COG1199	ATP-dependent helicase activity
C2U38_RS10290	COG1214	PFAM Peptidase M22, glycoprotease
C2U38_RS10295	COG3065	identical protein binding
C2U38_RS10305	COG0318	PFAM AMP-dependent synthetase and ligase
C2U38_RS10310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C2U38_RS10315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2U38_RS10320	COG4638	Rieske (2fe-2S)
C2U38_RS10325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2U38_RS10330	COG0473	3-isopropylmalate dehydrogenase activity
C2U38_RS10335	COG0583	DNA-binding transcription factor activity
C2U38_RS10345	COG2894	cell division
C2U38_RS10360	COG0179	Fumarylacetoacetate (FAA) hydrolase
C2U38_RS10390	COG2719	SpoVR family
C2U38_RS10400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C2U38_RS10410	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2U38_RS10435	COG0157	Belongs to the NadC ModD family
C2U38_RS10440	COG0500	methyltransferase
C2U38_RS10445	COG1120	ATPase activity
C2U38_RS10450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS10455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2U38_RS10470	COG1461	Dihydroxyacetone kinase
C2U38_RS10475	COG2376	Dihydroxyacetone kinase
C2U38_RS10480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2U38_RS10505	COG3039	Transposase
C2U38_RS10510	COG0789	Transcriptional regulator
C2U38_RS10515	COG2200	EAL domain
C2U38_RS10545	COG0702	epimerase
C2U38_RS10555	COG0667	Aldo Keto reductase
C2U38_RS10560	COG0656	L-ascorbic acid biosynthetic process
C2U38_RS10565	COG0641	radical SAM
C2U38_RS10570	COG2190	(PTS) system
C2U38_RS10570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS10570	COG1263	PTS System
C2U38_RS10585	COG1737	Transcriptional regulator
C2U38_RS10590	COG2149	membrane
C2U38_RS10630	COG5002	protein histidine kinase activity
C2U38_RS10690	COG1396	sequence-specific DNA binding
C2U38_RS10705	COG2003	Belongs to the UPF0758 family
C2U38_RS10715	COG4974	Belongs to the 'phage' integrase family
C2U38_RS10785	COG0582	viral genome integration into host DNA
C2U38_RS10790	COG0012	GTP binding
C2U38_RS10805	COG0527	aspartate kinase activity
C2U38_RS10810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2U38_RS10815	COG0076	glutamate decarboxylase activity
C2U38_RS10820	COG0659	secondary active sulfate transmembrane transporter activity
C2U38_RS10850	COG2890	protein-(glutamine-N5) methyltransferase activity
C2U38_RS10875	COG4572	Cation transport regulator
C2U38_RS10880	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C2U38_RS10890	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C2U38_RS10895	COG4932	domain protein
C2U38_RS10900	COG2197	response regulator
C2U38_RS10905	COG3850	Histidine kinase
C2U38_RS10915	COG2223	nitrite transmembrane transporter activity
C2U38_RS10920	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2U38_RS10925	COG1140	nitrate reductase beta subunit
C2U38_RS10930	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2U38_RS10935	COG2181	nitrate reductase activity
C2U38_RS10955	COG0788	formyltetrahydrofolate deformylase activity
C2U38_RS10965	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2U38_RS10970	COG0745	RESPONSE REGULATOR receiver
C2U38_RS10975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2U38_RS10985	COG1435	thymidine kinase activity
C2U38_RS10990	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS10990	COG1454	alcohol dehydrogenase
C2U38_RS10995	COG2095	MarC family integral membrane protein
C2U38_RS11025	COG0444	Belongs to the ABC transporter superfamily
C2U38_RS11035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2U38_RS11050	COG2350	Protein conserved in bacteria
C2U38_RS11075	COG3047	cAMP biosynthetic process
C2U38_RS11085	COG3706	GGDEF domain
C2U38_RS11115	COG0613	PHP domain protein
C2U38_RS11120	COG0009	L-threonylcarbamoyladenylate synthase
C2U38_RS11125	COG1187	pseudouridine synthase activity
C2U38_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS11140	COG0616	signal peptide processing
C2U38_RS11155	COG0583	DNA-binding transcription factor activity
C2U38_RS11165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C2U38_RS11175	COG0671	phosphoesterase, PA-phosphatase related
C2U38_RS11180	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C2U38_RS11185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C2U38_RS11195	COG0023	Translation Initiation Factor
C2U38_RS11205	COG1349	DNA-binding transcription factor activity
C2U38_RS11220	COG5001	Diguanylate cyclase
C2U38_RS11230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2U38_RS11230	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2U38_RS11235	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C2U38_RS11260	COG4172	Belongs to the ABC transporter superfamily
C2U38_RS11265	COG4171	peptide transport system, permease
C2U38_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS11285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C2U38_RS11290	COG1842	Phage shock protein A
C2U38_RS11300	COG1983	PspC domain protein
C2U38_RS11310	COG0366	Alpha amylase catalytic
C2U38_RS11315	COG1653	transport
C2U38_RS11320	COG1175	transmembrane transport
C2U38_RS11325	COG0395	ABC-type sugar transport system, permease component
C2U38_RS11330	COG1063	alcohol dehydrogenase
C2U38_RS11335	COG1082	Xylose isomerase domain protein TIM barrel
C2U38_RS11340	COG0673	inositol 2-dehydrogenase activity
C2U38_RS11345	COG1554	hydrolase, family 65, central catalytic
C2U38_RS11350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2U38_RS11365	COG1609	Transcriptional regulator
C2U38_RS11370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2U38_RS11375	COG3106	COG3106 Predicted ATPase
C2U38_RS11400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C2U38_RS11405	COG4948	Mandelate Racemase Muconate Lactonizing
C2U38_RS11410	COG2866	Carboxypeptidase
C2U38_RS11415	COG4166	transmembrane transport
C2U38_RS11420	COG1349	DNA-binding transcription factor activity
C2U38_RS11425	COG0346	lactoylglutathione lyase activity
C2U38_RS11440	COG0668	transmembrane transport
C2U38_RS11445	COG3182	Iron-regulated membrane protein
C2U38_RS11465	COG2840	Smr protein MutS2
C2U38_RS11470	COG3706	GGDEF domain
C2U38_RS11480	COG0840	transmembrane signaling receptor activity
C2U38_RS11495	COG0513	Belongs to the DEAD box helicase family
C2U38_RS11505	COG0589	response to stress
C2U38_RS11515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C2U38_RS11520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2U38_RS11520	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C2U38_RS11520	COG1013	pyruvate-flavodoxin oxidoreductase activity
C2U38_RS11520	COG0674	pyruvate-flavodoxin oxidoreductase activity
C2U38_RS11530	COG3042	response to heat
C2U38_RS11535	COG3187	Heat shock protein
C2U38_RS11540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2U38_RS11560	COG3784	Protein of unknown function (DUF1318)
C2U38_RS11565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2U38_RS11570	COG4589	Belongs to the CDS family
C2U38_RS11580	COG2267	carboxylic ester hydrolase activity
C2U38_RS11585	COG2453	phosphatase
C2U38_RS11585	COG0671	phosphoesterase, PA-phosphatase related
C2U38_RS11605	COG1643	Atp-dependent helicase
C2U38_RS11610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C2U38_RS11615	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS11620	COG3038	cytochrome b561
C2U38_RS11625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2U38_RS11630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2U38_RS11645	COG2801	Transposase and inactivated derivatives
C2U38_RS11670	COG0840	transmembrane signaling receptor activity
C2U38_RS11675	COG0583	DNA-binding transcription factor activity
C2U38_RS11680	COG1227	inorganic diphosphatase activity
C2U38_RS11685	COG5383	Protein conserved in bacteria
C2U38_RS11700	COG2841	Protein conserved in bacteria
C2U38_RS11705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2U38_RS11710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C2U38_RS11720	COG0500	methyltransferase
C2U38_RS11730	COG0697	spore germination
C2U38_RS11740	COG3135	benzoate transporter
C2U38_RS11745	COG1396	sequence-specific DNA binding
C2U38_RS11750	COG0826	peptidase U32
C2U38_RS11765	COG1294	oxidase, subunit
C2U38_RS11770	COG1271	oxidase subunit
C2U38_RS11775	COG1724	mRNA binding
C2U38_RS11780	COG1598	PFAM Uncharacterised protein family UPF0150
C2U38_RS11785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2U38_RS11790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2U38_RS11795	COG3842	ATPase activity
C2U38_RS11800	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2U38_RS11805	COG1177	transmembrane transport
C2U38_RS11815	COG2814	Major facilitator Superfamily
C2U38_RS11855	COG0747	negative chemotaxis
C2U38_RS11865	COG3238	Protein conserved in bacteria
C2U38_RS11870	COG1247	-acetyltransferase
C2U38_RS11880	COG2130	NADP-dependent
C2U38_RS11885	COG4772	TonB-dependent receptor
C2U38_RS11905	COG0840	transmembrane signaling receptor activity
C2U38_RS11910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2U38_RS11915	COG1473	amidohydrolase
C2U38_RS11920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2U38_RS11925	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C2U38_RS11940	COG1126	abc transporter atp-binding protein
C2U38_RS11945	COG0625	glutathione transferase activity
C2U38_RS11950	COG2271	Major facilitator Superfamily
C2U38_RS11960	COG1609	Transcriptional regulator
C2U38_RS11970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2U38_RS11975	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C2U38_RS11980	COG0384	phenazine biosynthesis protein PhzF
C2U38_RS11985	COG2181	nitrate reductase activity
C2U38_RS11990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2U38_RS11995	COG1140	nitrate reductase beta subunit
C2U38_RS12000	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2U38_RS12005	COG2223	nitrite transmembrane transporter activity
C2U38_RS12035	COG3383	formate dehydrogenase (NAD+) activity
C2U38_RS12035	COG0243	molybdopterin cofactor binding
C2U38_RS12040	COG3383	formate dehydrogenase (NAD+) activity
C2U38_RS12040	COG0243	molybdopterin cofactor binding
C2U38_RS12045	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS12050	COG2864	formate dehydrogenase
C2U38_RS12055	COG0488	(ABC) transporter
C2U38_RS12070	COG1764	response to oxidative stress
C2U38_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS12080	COG2610	gluconate transmembrane transporter activity
C2U38_RS12085	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2U38_RS12095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C2U38_RS12100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C2U38_RS12110	COG4608	Belongs to the ABC transporter superfamily
C2U38_RS12115	COG0444	Belongs to the ABC transporter superfamily
C2U38_RS12120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2U38_RS12125	COG0601	transmembrane transport
C2U38_RS12130	COG0747	negative chemotaxis
C2U38_RS12135	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
C2U38_RS12150	COG0840	transmembrane signaling receptor activity
C2U38_RS12155	COG1649	PFAM Uncharacterised BCR, COG1649
C2U38_RS12160	COG4628	conserved protein (DUF2132)
C2U38_RS12175	COG2801	Transposase and inactivated derivatives
C2U38_RS12195	COG3781	membrane
C2U38_RS12220	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS12225	COG0583	DNA-binding transcription factor activity
C2U38_RS12240	COG1846	Transcriptional regulator
C2U38_RS12255	COG0697	spore germination
C2U38_RS12280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS12285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2U38_RS12290	COG0589	response to stress
C2U38_RS12295	COG0659	secondary active sulfate transmembrane transporter activity
C2U38_RS12305	COG0410	ABC transporter
C2U38_RS12310	COG1129	ABC transporter
C2U38_RS12340	COG0339	signal peptide processing
C2U38_RS12345	COG4221	oxidoreductase activity
C2U38_RS12350	COG1802	Transcriptional regulator
C2U38_RS12360	COG0246	Mannitol dehydrogenase
C2U38_RS12365	COG0477	Major facilitator Superfamily
C2U38_RS12370	COG1063	alcohol dehydrogenase
C2U38_RS12375	COG4948	Mandelate Racemase Muconate Lactonizing
C2U38_RS12390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2U38_RS12405	COG0243	molybdopterin cofactor binding
C2U38_RS12410	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS12415	COG3302	dmso reductase anchor subunit
C2U38_RS12420	COG3381	protein complex oligomerization
C2U38_RS12430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C2U38_RS12435	COG1940	carbohydrate kinase activity
C2U38_RS12440	COG0583	DNA-binding transcription factor activity
C2U38_RS12445	COG2814	Major facilitator Superfamily
C2U38_RS12455	COG5002	protein histidine kinase activity
C2U38_RS12460	COG0745	RESPONSE REGULATOR receiver
C2U38_RS12475	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C2U38_RS12485	COG3591	Belongs to the peptidase S1B family
C2U38_RS12505	COG0628	permease
C2U38_RS12510	COG2814	Major facilitator Superfamily
C2U38_RS12515	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C2U38_RS12520	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C2U38_RS12530	COG0531	amino acid
C2U38_RS12540	COG3136	membrane protein required for alginate biosynthesis
C2U38_RS12545	COG0745	RESPONSE REGULATOR receiver
C2U38_RS12550	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
C2U38_RS12560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2U38_RS12570	COG2205	protein histidine kinase activity
C2U38_RS12585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS12585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS12590	COG1482	cell wall glycoprotein biosynthetic process
C2U38_RS12595	COG5339	Protein conserved in bacteria
C2U38_RS12600	COG1609	Transcriptional regulator
C2U38_RS12605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS12605	COG1263	PTS System
C2U38_RS12610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C2U38_RS12620	COG0673	inositol 2-dehydrogenase activity
C2U38_RS12670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C2U38_RS12685	COG0625	glutathione transferase activity
C2U38_RS12690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C2U38_RS12705	COG3895	Periplasmic Protein
C2U38_RS12730	COG1566	PFAM secretion protein HlyD family protein
C2U38_RS12745	COG4989	oxidoreductase activity
C2U38_RS12750	COG3313	Fe-S protein
C2U38_RS12755	COG1309	transcriptional regulator
C2U38_RS12760	COG1902	pentaerythritol trinitrate reductase activity
C2U38_RS12765	COG0346	lactoylglutathione lyase activity
C2U38_RS12775	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C2U38_RS12780	COG0791	NLP P60 protein
C2U38_RS12785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2U38_RS12790	COG2814	Major facilitator Superfamily
C2U38_RS12810	COG0583	DNA-binding transcription factor activity
C2U38_RS12815	COG2814	Major facilitator Superfamily
C2U38_RS12825	COG0307	riboflavin synthase, alpha
C2U38_RS12835	COG0564	pseudouridine synthase activity
C2U38_RS12850	COG0251	oxidation-reduction process
C2U38_RS12870	COG3300	MHYT domain
C2U38_RS12870	COG5001	Diguanylate cyclase
C2U38_RS12875	COG3272	Protein of unknown function (DUF1722)
C2U38_RS12880	COG0628	permease
C2U38_RS12895	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS12905	COG0583	DNA-binding transcription factor activity
C2U38_RS12910	COG0477	Major facilitator Superfamily
C2U38_RS12925	COG1942	4-Oxalocrotonate Tautomerase
C2U38_RS12935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C2U38_RS12980	COG4977	sequence-specific DNA binding
C2U38_RS12990	COG0386	Belongs to the glutathione peroxidase family
C2U38_RS13015	COG1120	ATPase activity
C2U38_RS13020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS13025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2U38_RS13030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2U38_RS13045	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C2U38_RS13055	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS13070	COG1113	amino acid transport
C2U38_RS13080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS13090	COG0765	amino acid transport
C2U38_RS13095	COG0765	amino acid transport
C2U38_RS13105	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
C2U38_RS13110	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS13120	COG2414	aldehyde ferredoxin oxidoreductase
C2U38_RS13125	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS13160	COG1464	Belongs to the NlpA lipoprotein family
C2U38_RS13165	COG2011	ABC-type metal ion transport system permease component
C2U38_RS13190	COG1376	ErfK ybiS ycfS ynhG family protein
C2U38_RS13205	COG0719	Fe-S assembly protein
C2U38_RS13210	COG0396	ATPase activity
C2U38_RS13215	COG0719	Fe-S assembly protein
C2U38_RS13220	COG0316	Belongs to the HesB IscA family
C2U38_RS13255	COG2050	protein possibly involved in aromatic compounds catabolism
C2U38_RS13260	COG0247	lactate metabolic process
C2U38_RS13260	COG0277	FAD linked oxidase domain protein
C2U38_RS13265	COG0628	permease
C2U38_RS13280	COG0738	Major facilitator superfamily
C2U38_RS13285	COG2271	Major facilitator Superfamily
C2U38_RS13300	COG4670	ketone body catabolic process
C2U38_RS13305	COG1960	acyl-CoA dehydrogenase activity
C2U38_RS13310	COG2207	Transcriptional regulator
C2U38_RS13310	COG1917	Cupin 2, conserved barrel domain protein
C2U38_RS13315	COG2086	electron transfer activity
C2U38_RS13320	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C2U38_RS13325	COG0644	oxidoreductase
C2U38_RS13330	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C2U38_RS13335	COG0318	PFAM AMP-dependent synthetase and ligase
C2U38_RS13340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2U38_RS13340	COG0574	Belongs to the PEP-utilizing enzyme family
C2U38_RS13350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2U38_RS13355	COG4256	Hemin uptake protein
C2U38_RS13360	COG4771	TonB-dependent receptor
C2U38_RS13365	COG3720	iron ion transport
C2U38_RS13370	COG4558	Periplasmic binding protein
C2U38_RS13375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2U38_RS13395	COG0791	NLP P60 protein
C2U38_RS13405	COG0386	Belongs to the glutathione peroxidase family
C2U38_RS13420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS13435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2U38_RS13465	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C2U38_RS13485	COG3137	Salt-induced outer membrane protein
C2U38_RS13490	COG1105	Belongs to the carbohydrate kinase PfkB family
C2U38_RS13495	COG3001	Fructosamine kinase
C2U38_RS13505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2U38_RS13515	COG1988	membrane-bound metal-dependent
C2U38_RS13520	COG1823	symporter activity
C2U38_RS13530	COG0753	catalase activity
C2U38_RS13540	COG1486	melibiose metabolic process
C2U38_RS13545	COG2169	Transcriptional regulator
C2U38_RS13545	COG1917	Cupin 2, conserved barrel domain protein
C2U38_RS13550	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2U38_RS13555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2U38_RS13560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2U38_RS13570	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2U38_RS13580	COG0322	excinuclease ABC activity
C2U38_RS13590	COG3678	ATP-independent chaperone mediated protein folding
C2U38_RS13630	COG0708	Exodeoxyribonuclease III
C2U38_RS13635	COG0398	Pfam SNARE associated Golgi protein
C2U38_RS13640	COG0398	Pfam SNARE associated Golgi protein
C2U38_RS13645	COG4134	Bacterial extracellular solute-binding protein
C2U38_RS13650	COG4135	transport system, permease component
C2U38_RS13655	COG4136	ATPase activity
C2U38_RS13660	COG2897	thiosulfate sulfurtransferase activity
C2U38_RS13665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2U38_RS13670	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2U38_RS13675	COG0494	nUDIX hydrolase
C2U38_RS13690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2U38_RS13700	COG0778	Nitroreductase
C2U38_RS13705	COG0616	signal peptide processing
C2U38_RS13710	COG0252	asparaginase activity
C2U38_RS13715	COG1335	isochorismatase
C2U38_RS13730	COG3139	Protein of unknown function (DUF1315)
C2U38_RS13750	COG0656	L-ascorbic acid biosynthetic process
C2U38_RS13765	COG3713	MltA-interacting MipA family protein
C2U38_RS13770	COG2766	serine protein kinase
C2U38_RS13780	COG0110	maltose O-acetyltransferase activity
C2U38_RS13790	COG2226	methyltransferase
C2U38_RS13795	COG2199	diguanylate cyclase activity
C2U38_RS13800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2U38_RS13810	COG2207	Transcriptional regulator
C2U38_RS13815	COG2807	transmembrane transport
C2U38_RS13820	COG0504	CTP synthase activity
C2U38_RS13825	COG3189	MarR family transcriptional regulator
C2U38_RS13830	COG3042	response to heat
C2U38_RS13835	COG2203	Gaf domain
C2U38_RS13835	COG2199	diguanylate cyclase activity
C2U38_RS13850	COG2261	transglycosylase associated protein
C2U38_RS13855	COG3383	formate dehydrogenase (NAD+) activity
C2U38_RS13870	COG3615	Tellurite resistance protein tehB
C2U38_RS13880	COG3443	Belongs to the bacterial solute-binding protein 9 family
C2U38_RS13895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2U38_RS13900	COG0601	transmembrane transport
C2U38_RS13905	COG0747	negative chemotaxis
C2U38_RS13910	COG4771	TonB-dependent receptor
C2U38_RS13930	COG1956	GAF domain-containing protein
C2U38_RS13935	COG2995	paraquat-inducible protein a
C2U38_RS13940	COG3008	intermembrane lipid transfer
C2U38_RS13970	COG2135	peptidase activity
C2U38_RS13975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2U38_RS14050	COG1196	nuclear chromosome segregation
C2U38_RS14235	COG1484	DNA-dependent DNA replication
C2U38_RS14290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2U38_RS14320	COG0582	viral genome integration into host DNA
C2U38_RS14330	COG1276	copper resistance
C2U38_RS14335	COG2372	response to copper ion
C2U38_RS14345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2U38_RS14350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2U38_RS14355	COG1770	oligopeptidase
C2U38_RS14360	COG2979	Protein of unknown function (DUF533)
C2U38_RS14370	COG3141	response to X-ray
C2U38_RS14380	COG0800	Aldolase
C2U38_RS14385	COG0129	dihydroxy-acid dehydratase activity
C2U38_RS14390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C2U38_RS14395	COG1737	Transcriptional regulator
C2U38_RS14405	COG1560	Kdo2-lipid A biosynthetic process
C2U38_RS14415	COG0739	heme binding
C2U38_RS14420	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C2U38_RS14430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2U38_RS14460	COG0582	viral genome integration into host DNA
C2U38_RS14470	COG0582	viral genome integration into host DNA
C2U38_RS14500	COG2850	peptidyl-arginine hydroxylation
C2U38_RS14530	COG3459	Glycosyltransferase 36 associated
C2U38_RS14545	COG1278	Cold shock
C2U38_RS14565	COG3344	reverse transcriptase
C2U38_RS14610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C2U38_RS14620	COG3318	Belongs to the UPF0149 family
C2U38_RS14620	COG3012	SEC-C Motif Domain Protein
C2U38_RS14670	COG3596	GTP binding
C2U38_RS14750	COG2197	response regulator
C2U38_RS14760	COG2197	response regulator
C2U38_RS14765	COG1126	abc transporter atp-binding protein
C2U38_RS14770	COG0765	amino acid transport
C2U38_RS14775	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C2U38_RS14780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS14825	COG0366	Alpha amylase catalytic
C2U38_RS14840	COG0425	Belongs to the sulfur carrier protein TusA family
C2U38_RS14875	COG2882	bacterial-type flagellum organization
C2U38_RS14935	COG5475	Uncharacterized small protein (DUF2158)
C2U38_RS14940	COG2354	Protein conserved in bacteria
C2U38_RS14945	COG0697	spore germination
C2U38_RS14950	COG3727	T/G mismatch-specific endonuclease activity
C2U38_RS14955	COG0270	DNA (cytosine-5-)-methyltransferase activity
C2U38_RS14960	COG1418	mRNA catabolic process
C2U38_RS15005	COG0582	viral genome integration into host DNA
C2U38_RS15110	COG2916	Histone family protein nucleoid-structuring protein H-NS
C2U38_RS15145	COG3311	Transcriptional regulator
C2U38_RS15160	COG1840	ABC-type Fe3 transport system, periplasmic component
C2U38_RS15165	COG1178	ABC-type Fe3 transport system permease component
C2U38_RS15175	COG1376	ErfK ybiS ycfS ynhG family protein
C2U38_RS15350	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
C2U38_RS15370	COG4656	Part of a membrane complex involved in electron transport
C2U38_RS15405	COG1289	transmembrane transporter activity
C2U38_RS15435	COG2925	Exonuclease
C2U38_RS15440	COG0531	amino acid
C2U38_RS15450	COG0583	DNA-binding transcription factor activity
C2U38_RS15455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2U38_RS15485	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C2U38_RS15525	COG3344	reverse transcriptase
C2U38_RS15575	COG3039	Transposase
C2U38_RS15625	COG3039	Transposase
C2U38_RS15665	COG1091	dTDP-4-dehydrorhamnose reductase activity
C2U38_RS15700	COG2327	Polysaccharide pyruvyl transferase
C2U38_RS15705	COG2244	polysaccharide biosynthetic process
C2U38_RS15710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C2U38_RS15715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C2U38_RS15720	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C2U38_RS15720	COG0662	Cupin 2, conserved barrel domain protein
C2U38_RS15725	COG0297	glycogen (starch) synthase activity
C2U38_RS15730	COG1051	belongs to the nudix hydrolase family
C2U38_RS15735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2U38_RS15740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C2U38_RS15745	COG0110	maltose O-acetyltransferase activity
C2U38_RS15750	COG1216	Glycosyl transferase, family 2
C2U38_RS15760	COG0438	transferase activity, transferring glycosyl groups
C2U38_RS15765	COG1045	serine acetyltransferase
C2U38_RS15770	COG0463	Glycosyl transferase, family 2
C2U38_RS15790	COG1253	flavin adenine dinucleotide binding
C2U38_RS15795	COG2982	Protein involved in outer membrane biogenesis
C2U38_RS15815	COG5001	Diguanylate cyclase
C2U38_RS15815	COG5002	protein histidine kinase activity
C2U38_RS15815	COG3447	MASE1 domain protein
C2U38_RS15820	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2U38_RS15830	COG0443	Heat shock 70 kDa protein
C2U38_RS15855	COG2205	protein histidine kinase activity
C2U38_RS15860	COG0745	RESPONSE REGULATOR receiver
C2U38_RS15870	COG0826	peptidase U32
C2U38_RS15875	COG0542	response to heat
C2U38_RS15885	COG1278	Cold shock
C2U38_RS15895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2U38_RS15900	COG2990	Protein conserved in bacteria
C2U38_RS15905	COG3593	DNA synthesis involved in DNA repair
C2U38_RS15915	COG2431	L-lysine efflux transmembrane transporter activity
C2U38_RS15925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2U38_RS15930	COG4529	Protein conserved in bacteria
C2U38_RS15940	COG0028	Belongs to the TPP enzyme family
C2U38_RS15945	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C2U38_RS15950	COG0702	epimerase
C2U38_RS15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2U38_RS15960	COG3023	N-Acetylmuramoyl-L-alanine amidase
C2U38_RS15975	COG1126	abc transporter atp-binding protein
C2U38_RS15980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS15985	COG4215	(ABC) transporter
C2U38_RS15990	COG4160	amino acid transport
C2U38_RS15995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS16005	COG1830	Aldolase
C2U38_RS16010	COG2211	Major facilitator Superfamily
C2U38_RS16015	COG1397	ADP-ribosylglycohydrolase
C2U38_RS16020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS16025	COG2188	Transcriptional regulator
C2U38_RS16030	COG0351	phosphomethylpyrimidine kinase
C2U38_RS16040	COG5455	response to cobalt ion
C2U38_RS16050	COG3188	usher protein
C2U38_RS16055	COG3121	Chaperone
C2U38_RS16080	COG4808	Protein conserved in bacteria
C2U38_RS16085	COG4807	Protein conserved in bacteria
C2U38_RS16095	COG3275	phosphorelay sensor kinase activity
C2U38_RS16100	COG0789	Transcriptional regulator
C2U38_RS16110	COG1174	glycine betaine transport
C2U38_RS16115	COG1125	glycine betaine transport
C2U38_RS16120	COG1174	glycine betaine transport
C2U38_RS16125	COG1732	Glycine betaine
C2U38_RS16130	COG1472	Belongs to the glycosyl hydrolase 3 family
C2U38_RS16135	COG0277	FAD linked oxidase domain protein
C2U38_RS16140	COG1686	Belongs to the peptidase S11 family
C2U38_RS16155	COG0586	Pfam SNARE associated Golgi protein
C2U38_RS16165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C2U38_RS16170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2U38_RS16175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2U38_RS16180	COG0625	glutathione transferase activity
C2U38_RS16195	COG2271	Major facilitator Superfamily
C2U38_RS16210	COG1346	cytolysis
C2U38_RS16220	COG2949	membrane
C2U38_RS16230	COG0493	'glutamate synthase
C2U38_RS16245	COG1129	ABC transporter
C2U38_RS16260	COG2311	Membrane
C2U38_RS16290	COG0833	amino acid
C2U38_RS16295	COG0583	DNA-binding transcription factor activity
C2U38_RS16300	COG2855	membrane
C2U38_RS16310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS16310	COG1522	sequence-specific DNA binding
C2U38_RS16315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2U38_RS16320	COG2313	pseudouridylate synthase activity
C2U38_RS16325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS16330	COG0583	DNA-binding transcription factor activity
C2U38_RS16340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2U38_RS16345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS16345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS16345	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C2U38_RS16350	COG1105	Belongs to the carbohydrate kinase PfkB family
C2U38_RS16375	COG3381	protein complex oligomerization
C2U38_RS16385	COG3005	denitrification pathway
C2U38_RS16390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2U38_RS16395	COG1312	Catalyzes the dehydration of D-mannonate
C2U38_RS16400	COG0246	Mannitol dehydrogenase
C2U38_RS16405	COG0523	cobalamin synthesis protein
C2U38_RS16410	COG0671	phosphoesterase, PA-phosphatase related
C2U38_RS16420	COG0791	NLP P60 protein
C2U38_RS16425	COG2200	EAL domain
C2U38_RS16430	COG4166	transmembrane transport
C2U38_RS16435	COG4174	ABC transporter (Permease)
C2U38_RS16440	COG4239	(ABC) transporter, permease
C2U38_RS16445	COG4172	Belongs to the ABC transporter superfamily
C2U38_RS16460	COG2814	Major facilitator Superfamily
C2U38_RS16465	COG1187	pseudouridine synthase activity
C2U38_RS16470	COG1061	Type III restriction enzyme res subunit
C2U38_RS16500	COG2197	response regulator
C2U38_RS16505	COG4235	cytochrome complex assembly
C2U38_RS16505	COG3088	subunit of a heme lyase
C2U38_RS16510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2U38_RS16515	COG1138	Cytochrome C-type biogenesis protein
C2U38_RS16525	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2U38_RS16530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2U38_RS16540	COG4133	protoheme IX ABC transporter activity
C2U38_RS16545	COG3005	denitrification pathway
C2U38_RS16550	COG3043	anaerobic respiration
C2U38_RS16555	COG0348	domain, Protein
C2U38_RS16560	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS16570	COG3062	negative regulation of establishment of protein localization
C2U38_RS16575	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS16575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS16590	COG0659	secondary active sulfate transmembrane transporter activity
C2U38_RS16595	COG2239	Acts as a magnesium transporter
C2U38_RS16600	COG4615	Cyclic peptide transporter
C2U38_RS16605	COG3145	DNA-N1-methyladenine dioxygenase activity
C2U38_RS16610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2U38_RS16610	COG2169	Transcriptional regulator
C2U38_RS16615	COG1477	protein flavinylation
C2U38_RS16630	COG2198	Histidine kinase
C2U38_RS16630	COG0642	Histidine kinase
C2U38_RS16645	COG3852	Histidine kinase
C2U38_RS16650	COG2204	response regulator
C2U38_RS16655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C2U38_RS16660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C2U38_RS16665	COG2031	fatty acid transporter
C2U38_RS16670	COG0183	Belongs to the thiolase family
C2U38_RS16695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2U38_RS16700	COG0584	glycerophosphoryl diester phosphodiesterase
C2U38_RS16710	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS16720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2U38_RS16730	COG0247	lactate metabolic process
C2U38_RS16750	COG2271	Major facilitator Superfamily
C2U38_RS16760	COG1414	Transcriptional regulator
C2U38_RS16845	COG1169	isochorismate synthase
C2U38_RS16850	COG4575	ribosome binding
C2U38_RS16855	COG2153	protein acetylation
C2U38_RS16865	COG0835	chemotaxis
C2U38_RS16865	COG0784	Response regulator, receiver
C2U38_RS16875	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2U38_RS16880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2U38_RS16890	COG0839	Belongs to the complex I subunit 6 family
C2U38_RS16915	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C2U38_RS16935	COG0583	DNA-binding transcription factor activity
C2U38_RS16940	COG0436	Aminotransferase
C2U38_RS16950	COG0471	metal ion transport
C2U38_RS16950	COG0490	domain, Protein
C2U38_RS16955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2U38_RS16980	COG1288	antiporter activity
C2U38_RS16990	COG0622	Phosphoesterase
C2U38_RS16995	COG0625	glutathione transferase activity
C2U38_RS17000	COG0625	glutathione transferase activity
C2U38_RS17005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2U38_RS17010	COG1090	epimerase
C2U38_RS17015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2U38_RS17020	COG4598	ABC transporter
C2U38_RS17035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS17050	COG0163	prenyltransferase activity
C2U38_RS17055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C2U38_RS17060	COG1286	toxin biosynthetic process
C2U38_RS17065	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C2U38_RS17070	COG0285	dihydrofolate synthase activity
C2U38_RS17080	COG0586	Pfam SNARE associated Golgi protein
C2U38_RS17090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2U38_RS17130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2U38_RS17145	COG3101	peptidyl-lysine hydroxylation
C2U38_RS17150	COG0730	response to heat
C2U38_RS17175	COG2062	phosphohistidine phosphatase, SixA
C2U38_RS17190	COG3691	Protein conserved in bacteria
C2U38_RS17195	COG2067	long-chain fatty acid transport protein
C2U38_RS17205	COG2116	formate transmembrane transporter activity
C2U38_RS17320	COG4695	Portal protein
C2U38_RS17330	COG4626	Terminase
C2U38_RS17330	COG1802	Transcriptional regulator
C2U38_RS17500	COG0582	viral genome integration into host DNA
C2U38_RS17510	COG0582	viral genome integration into host DNA
C2U38_RS17550	COG3039	Transposase
C2U38_RS17575	COG1446	asparaginase
C2U38_RS17580	COG0840	transmembrane signaling receptor activity
C2U38_RS17585	COG3122	Protein conserved in bacteria
C2U38_RS17620	COG1560	Kdo2-lipid A biosynthetic process
C2U38_RS17635	COG0436	Aminotransferase
C2U38_RS17645	COG3279	Response regulator of the LytR AlgR family
C2U38_RS17650	COG2207	Transcriptional regulator
C2U38_RS17665	COG1363	Peptidase, m42
C2U38_RS17670	COG0006	proline dipeptidase activity
C2U38_RS17675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS17680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS17705	COG3961	Belongs to the TPP enzyme family
C2U38_RS17710	COG0667	Aldo Keto reductase
C2U38_RS17720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS17720	COG1263	PTS System
C2U38_RS17725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C2U38_RS17730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2U38_RS17745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2U38_RS17765	COG3415	Transposase
C2U38_RS17770	COG3415	Transposase
C2U38_RS17805	COG0583	DNA-binding transcription factor activity
C2U38_RS17810	COG0385	Bile acid
C2U38_RS17815	COG3530	Putative quorum-sensing-regulated virulence factor
C2U38_RS17880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C2U38_RS17885	COG4208	sulfate ABC transporter
C2U38_RS17890	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C2U38_RS17895	COG4150	thiosulfate binding
C2U38_RS17905	COG2186	Transcriptional regulator
C2U38_RS17910	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2U38_RS17915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2U38_RS17930	COG0165	Argininosuccinate lyase
C2U38_RS17935	COG2837	iron assimilation
C2U38_RS17955	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2U38_RS17965	COG2207	Transcriptional regulator
C2U38_RS18030	COG4812	Cobalamin adenosyltransferase
C2U38_RS18035	COG4766	ethanolamine catabolic process
C2U38_RS18060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2U38_RS18065	COG5342	invasion associated locus B
C2U38_RS18075	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS18075	COG0493	'glutamate synthase
C2U38_RS18080	COG3850	Histidine kinase
C2U38_RS18085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2U38_RS18095	COG1393	Belongs to the ArsC family
C2U38_RS18110	COG0400	carboxylic ester hydrolase activity
C2U38_RS18120	COG2321	neutral zinc metallopeptidase
C2U38_RS18130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C2U38_RS18140	COG2716	regulation of RNA biosynthetic process
C2U38_RS18145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2U38_RS18150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2U38_RS18155	COG0700	Nucleoside recognition
C2U38_RS18160	COG3366	ferrous iron transmembrane transporter activity
C2U38_RS18165	COG0628	permease
C2U38_RS18170	COG4783	chaperone-mediated protein folding
C2U38_RS18175	COG1393	Belongs to the ArsC family
C2U38_RS18185	COG2233	PERMEase
C2U38_RS18195	COG2723	6-phospho-beta-galactosidase activity
C2U38_RS18205	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C2U38_RS18220	COG2200	EAL domain
C2U38_RS18235	COG0517	IMP dehydrogenase activity
C2U38_RS18235	COG0516	GMP reductase activity
C2U38_RS18240	COG1570	exodeoxyribonuclease VII activity
C2U38_RS18245	COG1645	bacterial-type flagellum-dependent swarming motility
C2U38_RS18270	COG2976	Protein conserved in bacteria
C2U38_RS18305	COG4953	penicillin-binding protein 1C
C2U38_RS18310	COG2373	Large extracellular alpha-helical protein
C2U38_RS18315	COG2897	thiosulfate sulfurtransferase activity
C2U38_RS18330	COG2975	iron-sulfur cluster assembly
C2U38_RS18335	COG0633	Ferredoxin
C2U38_RS18360	COG0822	iron-sulfur transferase activity
C2U38_RS18385	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
C2U38_RS18390	COG3683	transport system, periplasmic component
C2U38_RS18400	COG1129	ABC transporter
C2U38_RS18405	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS18415	COG1069	ribulokinase activity
C2U38_RS18420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2U38_RS18420	COG0517	IMP dehydrogenase activity
C2U38_RS18425	COG3711	transcriptional antiterminator
C2U38_RS18430	COG2814	Major facilitator Superfamily
C2U38_RS18435	COG3539	Fimbrial protein
C2U38_RS18440	COG3121	Chaperone
C2U38_RS18445	COG3188	usher protein
C2U38_RS18450	COG3539	Fimbrial protein
C2U38_RS18455	COG0583	DNA-binding transcription factor activity
C2U38_RS18460	COG4638	Rieske (2fe-2S)
C2U38_RS18485	COG2017	converts alpha-aldose to the beta-anomer
C2U38_RS18490	COG1063	alcohol dehydrogenase
C2U38_RS18495	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS18500	COG1129	ABC transporter
C2U38_RS18505	COG1879	ABC-type sugar transport system periplasmic component
C2U38_RS18510	COG0457	Tetratricopeptide repeat
C2U38_RS18515	COG1940	carbohydrate kinase activity
C2U38_RS18530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C2U38_RS18530	COG1017	nitric oxide dioxygenase activity
C2U38_RS18535	COG0347	Belongs to the P(II) protein family
C2U38_RS18540	COG2204	response regulator
C2U38_RS18545	COG3170	Tfp pilus assembly protein FimV
C2U38_RS18550	COG2205	protein histidine kinase activity
C2U38_RS18570	COG0560	Phosphoserine phosphatase
C2U38_RS18575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS18575	COG1263	PTS System
C2U38_RS18580	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C2U38_RS18585	COG1737	Transcriptional regulator
C2U38_RS18590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS18600	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C2U38_RS18630	COG0681	Belongs to the peptidase S26 family
C2U38_RS18640	COG3086	response to oxidative stress
C2U38_RS18645	COG3026	antisigma factor binding
C2U38_RS18655	COG1595	DNA-templated transcription, initiation
C2U38_RS18665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C2U38_RS18675	COG0513	Belongs to the DEAD box helicase family
C2U38_RS18690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2U38_RS18695	COG3118	belongs to the thioredoxin family
C2U38_RS18700	COG3148	PFAM DTW domain containing protein
C2U38_RS18710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2U38_RS18715	COG5544	Lipoprotein
C2U38_RS18720	COG0477	Major facilitator Superfamily
C2U38_RS18745	COG0542	response to heat
C2U38_RS18760	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2U38_RS18765	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2U38_RS18775	COG1605	Chorismate mutase
C2U38_RS18775	COG0077	Prephenate dehydratase
C2U38_RS18780	COG0287	Prephenate dehydrogenase
C2U38_RS18780	COG1605	Chorismate mutase
C2U38_RS18785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C2U38_RS18800	COG2199	diguanylate cyclase activity
C2U38_RS18805	COG2885	chlorophyll binding
C2U38_RS18830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2U38_RS18835	COG4137	Cytochrome C assembly protein
C2U38_RS18840	COG4536	flavin adenine dinucleotide binding
C2U38_RS18860	COG0497	DNA recombination
C2U38_RS18875	COG2867	negative regulation of translational initiation
C2U38_RS18900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2U38_RS18910	COG0582	viral genome integration into host DNA
C2U38_RS18985	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS18995	COG3596	GTP binding
C2U38_RS19005	COG2378	regulation of single-species biofilm formation
C2U38_RS19035	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS19040	COG2963	transposase activity
C2U38_RS19050	COG2003	Belongs to the UPF0758 family
C2U38_RS19075	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS19080	COG2378	regulation of single-species biofilm formation
C2U38_RS19090	COG2200	EAL domain
C2U38_RS19115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C2U38_RS19145	COG0438	transferase activity, transferring glycosyl groups
C2U38_RS19145	COG0297	glycogen (starch) synthase activity
C2U38_RS19150	COG0438	transferase activity, transferring glycosyl groups
C2U38_RS19195	COG3121	Chaperone
C2U38_RS19200	COG3188	usher protein
C2U38_RS19275	COG3039	Transposase
C2U38_RS19280	COG1285	pathogenesis
C2U38_RS19290	COG0579	oxidoreductase
C2U38_RS19295	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS19300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C2U38_RS19305	COG1113	amino acid transport
C2U38_RS19310	COG1802	Transcriptional regulator
C2U38_RS19315	COG1652	LysM domain
C2U38_RS19320	COG0401	homolog of Blt101
C2U38_RS19325	COG0640	Transcriptional regulator
C2U38_RS19330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2U38_RS19360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2U38_RS19395	COG4176	ABC-type proline glycine betaine transport system permease component
C2U38_RS19405	COG2814	Major facilitator Superfamily
C2U38_RS19410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C2U38_RS19420	COG1846	Transcriptional regulator
C2U38_RS19425	COG1566	PFAM secretion protein HlyD family protein
C2U38_RS19430	COG2814	Major facilitator Superfamily
C2U38_RS19445	COG1238	metal cluster binding
C2U38_RS19450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2U38_RS19480	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C2U38_RS19500	COG1546	Belongs to the CinA family
C2U38_RS19505	COG2951	lytic endotransglycosylase activity
C2U38_RS19510	COG3730	PTS system glucitol sorbitol-specific
C2U38_RS19515	COG3732	PTS system glucitol sorbitol-specific
C2U38_RS19525	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS19530	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS19535	COG1349	DNA-binding transcription factor activity
C2U38_RS19540	COG0517	IMP dehydrogenase activity
C2U38_RS19540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2U38_RS19560	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C2U38_RS19565	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS19570	COG1609	Transcriptional regulator
C2U38_RS19575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS19575	COG1263	PTS System
C2U38_RS19580	COG2723	6-phospho-beta-galactosidase activity
C2U38_RS19595	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2U38_RS19605	COG3260	NADH ubiquinone oxidoreductase 20
C2U38_RS19610	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C2U38_RS19615	COG3261	NADH dehydrogenase
C2U38_RS19615	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C2U38_RS19620	COG0650	Formate hydrogenlyase subunit 4
C2U38_RS19625	COG0651	ATP synthesis coupled electron transport
C2U38_RS19630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS19645	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C2U38_RS19650	COG0298	carbon dioxide binding
C2U38_RS19655	COG0409	Hydrogenase expression formation protein
C2U38_RS19660	COG0309	Hydrogenase expression formation protein (HypE)
C2U38_RS19680	COG1121	(ABC) transporter
C2U38_RS19685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2U38_RS19690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2U38_RS19695	COG2200	EAL domain
C2U38_RS19745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C2U38_RS19755	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C2U38_RS19875	COG0582	viral genome integration into host DNA
C2U38_RS19890	COG2801	Transposase and inactivated derivatives
C2U38_RS19955	COG1388	LysM domain
C2U38_RS19955	COG4942	peptidase
C2U38_RS19970	COG2801	Transposase and inactivated derivatives
C2U38_RS19980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2U38_RS19985	COG1518	maintenance of DNA repeat elements
C2U38_RS20000	COG1857	crispr-associated protein
C2U38_RS20015	COG1203	CRISPR-associated helicase, Cas3
C2U38_RS20035	COG0720	synthase
C2U38_RS20040	COG0644	oxidoreductase
C2U38_RS20045	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C2U38_RS20050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C2U38_RS20055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C2U38_RS20060	COG2086	electron transfer activity
C2U38_RS20065	COG0477	Major facilitator Superfamily
C2U38_RS20070	COG0277	FAD linked oxidase domain protein
C2U38_RS20075	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS20080	COG2223	nitrite transmembrane transporter activity
C2U38_RS20085	COG1070	Carbohydrate kinase
C2U38_RS20090	COG0602	queuosine metabolic process
C2U38_RS20095	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C2U38_RS20100	COG2190	(PTS) system
C2U38_RS20100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2U38_RS20100	COG1263	PTS System
C2U38_RS20105	COG1737	Transcriptional regulator
C2U38_RS20120	COG3956	TIGRFAM MazG family protein
C2U38_RS20125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2U38_RS20135	COG4999	Histidine kinase
C2U38_RS20135	COG3850	Histidine kinase
C2U38_RS20135	COG2205	protein histidine kinase activity
C2U38_RS20135	COG3437	response regulator, receiver
C2U38_RS20140	COG1929	Belongs to the glycerate kinase type-1 family
C2U38_RS20145	COG4948	Mandelate Racemase Muconate Lactonizing
C2U38_RS20150	COG4948	Mandelate Racemase Muconate Lactonizing
C2U38_RS20155	COG2271	Major facilitator Superfamily
C2U38_RS20160	COG0716	FMN binding
C2U38_RS20165	COG0564	pseudouridine synthase activity
C2U38_RS20170	COG3098	single-species biofilm formation
C2U38_RS20185	COG1611	Belongs to the LOG family
C2U38_RS20190	COG0814	amino acid
C2U38_RS20195	COG1760	l-serine dehydratase
C2U38_RS20200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C2U38_RS20205	COG1454	alcohol dehydrogenase
C2U38_RS20210	COG0235	Class ii aldolase
C2U38_RS20230	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS20235	COG1129	ABC transporter
C2U38_RS20245	COG1070	Carbohydrate kinase
C2U38_RS20255	COG1349	DNA-binding transcription factor activity
C2U38_RS20265	COG2363	Small membrane protein
C2U38_RS20270	COG0583	DNA-binding transcription factor activity
C2U38_RS20280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C2U38_RS20285	COG2166	iron-sulfur cluster assembly
C2U38_RS20290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C2U38_RS20295	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C2U38_RS20315	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2U38_RS20320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C2U38_RS20320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C2U38_RS20325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C2U38_RS20330	COG1074	ATP-dependent DNA helicase activity
C2U38_RS20340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C2U38_RS20345	COG4967	type IV pilus modification protein PilV
C2U38_RS20355	COG4795	General secretion pathway protein
C2U38_RS20360	COG2165	general secretion pathway protein
C2U38_RS20395	COG0861	Integral membrane protein TerC family
C2U38_RS20405	COG0667	Aldo Keto reductase
C2U38_RS20430	COG1609	Transcriptional regulator
C2U38_RS20440	COG0583	DNA-binding transcription factor activity
C2U38_RS20445	COG1794	racemase activity, acting on amino acids and derivatives
C2U38_RS20455	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS20465	COG0183	Belongs to the thiolase family
C2U38_RS20480	COG0814	amino acid
C2U38_RS20495	COG0402	S-adenosylhomocysteine deaminase activity
C2U38_RS20500	COG0549	Belongs to the carbamate kinase family
C2U38_RS20510	COG1304	FMN binding
C2U38_RS20515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2U38_RS20525	COG0666	response to abiotic stimulus
C2U38_RS20530	COG0583	DNA-binding transcription factor activity
C2U38_RS20535	COG2388	GCN5-related N-acetyl-transferase
C2U38_RS20540	COG3592	Divergent 4Fe-4S mono-cluster
C2U38_RS20550	COG1215	transferase activity, transferring glycosyl groups
C2U38_RS20555	COG1649	PFAM Uncharacterised BCR, COG1649
C2U38_RS20555	COG0726	polysaccharide deacetylase
C2U38_RS20560	COG0457	Tetratricopeptide repeat
C2U38_RS20565	COG3039	Transposase
C2U38_RS20575	COG0457	Tetratricopeptide repeat
C2U38_RS20580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2U38_RS20585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C2U38_RS20600	COG4942	peptidase
C2U38_RS20620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C2U38_RS20645	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C2U38_RS20660	COG1272	protein, Hemolysin III
C2U38_RS20670	COG1737	Transcriptional regulator
C2U38_RS20675	COG2723	6-phospho-beta-galactosidase activity
C2U38_RS20680	COG1028	Short-chain dehydrogenase reductase Sdr
C2U38_RS20700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2U38_RS20705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C2U38_RS20710	COG0006	proline dipeptidase activity
C2U38_RS20735	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C2U38_RS20740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2U38_RS20755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C2U38_RS20755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
C2U38_RS20760	COG1703	isobutyryl-CoA mutase activity
C2U38_RS20765	COG1024	Enoyl-CoA hydratase
C2U38_RS20770	COG0427	acetyl-CoA hydrolase
C2U38_RS20775	COG0583	DNA-binding transcription factor activity
C2U38_RS20780	COG2968	Membrane
C2U38_RS20785	COG1279	arginine transmembrane transporter activity
C2U38_RS20795	COG0668	transmembrane transport
C2U38_RS20800	COG0583	DNA-binding transcription factor activity
C2U38_RS20810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2U38_RS20815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2U38_RS20820	COG2271	Major facilitator Superfamily
C2U38_RS20825	COG0549	Belongs to the carbamate kinase family
C2U38_RS20830	COG0191	fructose-bisphosphate aldolase activity
C2U38_RS20850	COG1072	(Pantothenic acid kinase))
C2U38_RS20860	COG1494	fructose-1,6-bisphosphatase
C2U38_RS20865	COG1063	alcohol dehydrogenase
C2U38_RS20870	COG2213	PTS system mannitol-specific
C2U38_RS20875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS20895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2U38_RS20900	COG0501	Belongs to the peptidase M48B family
C2U38_RS20910	COG1166	arginine decarboxylase activity
C2U38_RS20935	COG2814	Major facilitator Superfamily
C2U38_RS20940	COG3091	SprT-like family
C2U38_RS20945	COG2356	endonuclease I
C2U38_RS20950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C2U38_RS20955	COG0189	ligase activity
C2U38_RS20970	COG2805	Type II/IV secretion system protein
C2U38_RS20985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C2U38_RS20990	COG0762	integral membrane protein
C2U38_RS21005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2U38_RS21010	COG0252	asparaginase activity
C2U38_RS21020	COG3171	Protein conserved in bacteria
C2U38_RS21030	COG1194	a g-specific adenine glycosylase
C2U38_RS21045	COG2211	Major facilitator Superfamily
C2U38_RS21050	COG1982	Orn Lys Arg decarboxylase major
C2U38_RS21060	COG1811	Na channel or pump
C2U38_RS21070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C2U38_RS21080	COG0210	DNA helicase
C2U38_RS21175	COG3039	Transposase
C2U38_RS21190	COG3039	Transposase
C2U38_RS21225	COG3344	reverse transcriptase
C2U38_RS21260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C2U38_RS21275	COG0488	(ABC) transporter
C2U38_RS21280	COG3173	Aminoglycoside phosphotransferase
C2U38_RS21295	COG1528	Iron-storage protein
C2U38_RS21305	COG3039	Transposase
C2U38_RS21335	COG1309	transcriptional regulator
C2U38_RS21350	COG1136	(ABC) transporter
C2U38_RS21365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS21380	COG1342	Belongs to the UPF0251 family
C2U38_RS21395	COG0783	Belongs to the Dps family
C2U38_RS21400	COG0640	Transcriptional regulator
C2U38_RS21430	COG0840	transmembrane signaling receptor activity
C2U38_RS21435	COG0412	Dienelactone hydrolase
C2U38_RS21445	COG1846	Transcriptional regulator
C2U38_RS21505	COG3039	Transposase
C2U38_RS21555	COG2885	chlorophyll binding
C2U38_RS21580	COG0754	glutathionylspermidine amidase activity
C2U38_RS21585	COG0243	molybdopterin cofactor binding
C2U38_RS21590	COG0625	glutathione transferase activity
C2U38_RS21595	COG0298	carbon dioxide binding
C2U38_RS21605	COG1773	rubredoxin
C2U38_RS21610	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2U38_RS21615	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C2U38_RS21620	COG5557	Pfam Polysulphide reductase, NrfD
C2U38_RS21625	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS21630	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C2U38_RS21640	COG0840	transmembrane signaling receptor activity
C2U38_RS21650	COG0667	Aldo Keto reductase
C2U38_RS21670	COG0848	biopolymer transport protein
C2U38_RS21685	COG0626	cystathionine gamma-synthase activity
C2U38_RS21690	COG0586	Pfam SNARE associated Golgi protein
C2U38_RS21695	COG2207	Transcriptional regulator
C2U38_RS21700	COG1979	alcohol dehydrogenase
C2U38_RS21705	COG0656	L-ascorbic acid biosynthetic process
C2U38_RS21720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2U38_RS21740	COG3111	PFAM Bacterial OB fold (BOF) protein
C2U38_RS21755	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2U38_RS21760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C2U38_RS21765	COG0187	DNA topoisomerase II activity
C2U38_RS21770	COG3150	esterase
C2U38_RS21775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C2U38_RS21780	COG3151	Protein conserved in bacteria
C2U38_RS21785	COG0494	nUDIX hydrolase
C2U38_RS21790	COG1538	Outer membrane efflux protein
C2U38_RS21805	COG0754	glutathionylspermidine amidase activity
C2U38_RS21810	COG3384	dioxygenase
C2U38_RS21885	COG3025	triphosphatase activity
C2U38_RS21895	COG4991	sh3 domain protein
C2U38_RS21910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2U38_RS21925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS21930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS21960	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C2U38_RS21970	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C2U38_RS21975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C2U38_RS21985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C2U38_RS21995	COG0358	DNA primase activity
C2U38_RS22045	COG2003	Belongs to the UPF0758 family
C2U38_RS22055	COG3468	outer membrane autotransporter barrel domain protein
C2U38_RS22060	COG2378	regulation of single-species biofilm formation
C2U38_RS22070	COG3596	GTP binding
C2U38_RS22075	COG3039	Transposase
C2U38_RS22105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C2U38_RS22155	COG4983	Phage plasmid primase, P4 family domain protein
C2U38_RS22250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C2U38_RS22260	COG2375	cellular response to nickel ion
C2U38_RS22265	COG1695	Transcriptional regulator
C2U38_RS22270	COG0840	transmembrane signaling receptor activity
C2U38_RS22280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2U38_RS22285	COG1609	Transcriptional regulator
C2U38_RS22290	COG3250	beta-galactosidase activity
C2U38_RS22295	COG2731	YhcH YjgK YiaL family protein
C2U38_RS22310	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
C2U38_RS22315	COG0366	Alpha amylase catalytic
C2U38_RS22320	COG0395	ABC-type sugar transport system, permease component
C2U38_RS22325	COG1175	transmembrane transport
C2U38_RS22335	COG1609	Transcriptional regulator
C2U38_RS22350	COG1902	pentaerythritol trinitrate reductase activity
C2U38_RS22350	COG0446	pyridine nucleotide-disulphide oxidoreductase
C2U38_RS22360	COG1451	nucleotide metabolic process
C2U38_RS22365	COG0673	inositol 2-dehydrogenase activity
C2U38_RS22385	COG2721	sulfolactate sulfo-lyase activity
C2U38_RS22395	COG2271	Major facilitator Superfamily
C2U38_RS22400	COG2186	Transcriptional regulator
C2U38_RS22405	COG0586	Pfam SNARE associated Golgi protein
C2U38_RS22415	COG1422	Protein of unknown function (DUF1090)
C2U38_RS22420	COG4575	ribosome binding
C2U38_RS22425	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
C2U38_RS22435	COG2259	Doxx family
C2U38_RS22440	COG0435	Glutathione S-transferase
C2U38_RS22445	COG3152	Membrane
C2U38_RS22450	COG0583	DNA-binding transcription factor activity
C2U38_RS22455	COG2801	Transposase and inactivated derivatives
C2U38_RS22465	COG1741	Belongs to the pirin family
C2U38_RS22480	COG0814	amino acid
C2U38_RS22485	COG1760	l-serine dehydratase
C2U38_RS22490	COG0251	oxidation-reduction process
C2U38_RS22495	COG1882	Formate acetyltransferase
C2U38_RS22515	COG0583	DNA-binding transcription factor activity
C2U38_RS22525	COG3344	reverse transcriptase
C2U38_RS22540	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS22560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS22580	COG1929	Belongs to the glycerate kinase type-1 family
C2U38_RS22585	COG2084	Dehydrogenase
C2U38_RS22595	COG2271	Major facilitator Superfamily
C2U38_RS22605	COG2721	sulfolactate sulfo-lyase activity
C2U38_RS22620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS22625	COG3414	Phosphotransferase system galactitol-specific IIB component
C2U38_RS22630	COG3775	system Galactitol-specific IIC component
C2U38_RS22635	COG1063	alcohol dehydrogenase
C2U38_RS22650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C2U38_RS22655	COG3107	peptidoglycan biosynthetic process
C2U38_RS22670	COG2823	Periplasmic or secreted lipoprotein
C2U38_RS22675	COG0702	epimerase
C2U38_RS22690	COG3153	acetyltransferase
C2U38_RS22695	COG3154	lipid carrier protein
C2U38_RS22700	COG0826	peptidase U32
C2U38_RS22705	COG0826	peptidase U32
C2U38_RS22710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2U38_RS22715	COG0814	amino acid
C2U38_RS22720	COG0513	Belongs to the DEAD box helicase family
C2U38_RS22745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C2U38_RS22755	COG0195	Participates in both transcription termination and antitermination
C2U38_RS22780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2U38_RS22785	COG0583	DNA-binding transcription factor activity
C2U38_RS22790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2U38_RS22795	COG3069	C4-dicarboxylate transmembrane transporter activity
C2U38_RS22805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C2U38_RS22810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C2U38_RS22820	COG1534	Rna-binding protein
C2U38_RS22835	COG2027	D-alanyl-D-alanine carboxypeptidase
C2U38_RS22845	COG0697	spore germination
C2U38_RS22850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C2U38_RS22855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C2U38_RS22860	COG0142	geranyltranstransferase activity
C2U38_RS22865	COG3423	Transcriptional regulator
C2U38_RS22875	COG5007	Belongs to the BolA IbaG family
C2U38_RS22880	COG3113	response to antibiotic
C2U38_RS22885	COG2854	intermembrane phospholipid transfer
C2U38_RS22890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C2U38_RS22895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C2U38_RS22900	COG1127	ABC transporter
C2U38_RS22905	COG0530	calcium, potassium:sodium antiporter activity
C2U38_RS22910	COG0517	IMP dehydrogenase activity
C2U38_RS22910	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2U38_RS22915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C2U38_RS22920	COG3117	lipopolysaccharide transmembrane transporter activity
C2U38_RS22925	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C2U38_RS22930	COG1137	ATPase activity
C2U38_RS22940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C2U38_RS22955	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS22965	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C2U38_RS22970	COG2198	Histidine kinase
C2U38_RS22970	COG5002	protein histidine kinase activity
C2U38_RS22970	COG0784	Response regulator, receiver
C2U38_RS22975	COG1242	4 iron, 4 sulfur cluster binding
C2U38_RS22985	COG0070	glutamate synthase
C2U38_RS22985	COG0069	glutamate synthase activity
C2U38_RS22985	COG0067	glutamate synthase
C2U38_RS22990	COG0493	'glutamate synthase
C2U38_RS23000	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2U38_RS23005	COG0402	S-adenosylhomocysteine deaminase activity
C2U38_RS23010	COG2731	YhcH YjgK YiaL family protein
C2U38_RS23040	COG3069	C4-dicarboxylate transmembrane transporter activity
C2U38_RS23045	COG2969	positive regulation of protein catabolic process
C2U38_RS23050	COG0625	glutathione transferase activity
C2U38_RS23075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C2U38_RS23080	COG3105	Protein conserved in bacteria
C2U38_RS23085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2U38_RS23090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2U38_RS23115	COG2732	(Barnase) inhibitor
C2U38_RS23135	COG0583	DNA-binding transcription factor activity
C2U38_RS23140	COG0312	modulator of DNA gyrase
C2U38_RS23145	COG3164	Protein of unknown function
C2U38_RS23160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C2U38_RS23165	COG1792	Involved in formation and maintenance of cell shape
C2U38_RS23170	COG1077	Cell shape determining protein MreB Mrl
C2U38_RS23180	COG2200	EAL domain
C2U38_RS23180	COG2199	diguanylate cyclase activity
C2U38_RS23185	COG0604	alcohol dehydrogenase
C2U38_RS23205	COG0511	ligase activity, forming carbon-carbon bonds
C2U38_RS23210	COG0439	Biotin carboxylase
C2U38_RS23215	COG3924	membrane
C2U38_RS23220	COG4145	pantothenate transmembrane transporter activity
C2U38_RS23250	COG4626	Terminase
C2U38_RS23250	COG1802	Transcriptional regulator
C2U38_RS23340	COG3561	AntA/AntB antirepressor
C2U38_RS23355	COG0582	viral genome integration into host DNA
C2U38_RS23360	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C2U38_RS23370	COG1309	transcriptional regulator
C2U38_RS23385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C2U38_RS23390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2U38_RS23400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2U38_RS23405	COG4597	amino acid ABC transporter
C2U38_RS23410	COG0765	amino acid transport
C2U38_RS23415	COG1126	abc transporter atp-binding protein
C2U38_RS23455	COG3290	protein histidine kinase activity
C2U38_RS23460	COG4565	transcriptional regulatory protein
C2U38_RS23465	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2U38_RS23470	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS23470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C2U38_RS23475	COG3647	Membrane
C2U38_RS23485	COG2211	Major facilitator Superfamily
C2U38_RS23490	COG1486	melibiose metabolic process
C2U38_RS23495	COG2169	Transcriptional regulator
C2U38_RS23500	COG1982	Orn Lys Arg decarboxylase major
C2U38_RS23505	COG2207	Transcriptional regulator
C2U38_RS23510	COG0531	amino acid
C2U38_RS23560	COG2824	Alkylphosphonate utilization operon protein PhnA
C2U38_RS23565	COG2764	glyoxalase bleomycin resistance protein dioxygenase
C2U38_RS23570	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C2U38_RS23575	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C2U38_RS23580	COG3639	organic phosphonate transmembrane transporter activity
C2U38_RS23585	COG2188	Transcriptional regulator
C2U38_RS23590	COG3624	Phosphonate C-P lyase system protein PhnG
C2U38_RS23595	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
C2U38_RS23600	COG3626	phosphonate metabolism
C2U38_RS23605	COG3627	carbon phosphorus lyase activity
C2U38_RS23610	COG4107	phosphonate C-P lyase system protein PhnK
C2U38_RS23615	COG4778	phosphonate C-P lyase system protein PhnL
C2U38_RS23620	COG3454	Phosphonate metabolism
C2U38_RS23625	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
C2U38_RS23630	COG0456	acetyltransferase
C2U38_RS23635	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C2U38_RS23660	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS23675	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS23705	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C2U38_RS23710	COG1301	dicarboxylic acid transport
C2U38_RS23715	COG4235	cytochrome complex assembly
C2U38_RS23720	COG3088	subunit of a heme lyase
C2U38_RS23740	COG3301	Polysulphide reductase, NrfD
C2U38_RS23745	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS23750	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C2U38_RS23760	COG2801	Transposase and inactivated derivatives
C2U38_RS23780	COG3162	membrane
C2U38_RS23790	COG1346	cytolysis
C2U38_RS23795	COG1380	Effector of murein hydrolase LrgA
C2U38_RS23800	COG0583	DNA-binding transcription factor activity
C2U38_RS23805	COG0025	NhaP-type Na H and K H
C2U38_RS23810	COG2252	PERMEase
C2U38_RS23820	COG0789	Transcriptional regulator
C2U38_RS23830	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C2U38_RS23840	COG0629	single-stranded DNA binding
C2U38_RS23850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C2U38_RS23855	COG2315	Protein conserved in bacteria
C2U38_RS23860	COG3700	Belongs to the class B bacterial acid phosphatase family
C2U38_RS23865	COG1448	Aminotransferase
C2U38_RS23875	COG0305	Participates in initiation and elongation during chromosome replication
C2U38_RS23890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2U38_RS23955	COG1196	nuclear chromosome segregation
C2U38_RS24005	COG1030	water channel activity
C2U38_RS24025	COG4220	transposase activity
C2U38_RS24040	COG3179	chitinase
C2U38_RS24070	COG1403	HNH endonuclease
C2U38_RS24075	COG3645	SOS response
C2U38_RS24075	COG3646	Phage regulatory protein
C2U38_RS24090	COG4725	Belongs to the MT-A70-like family
C2U38_RS24095	COG4626	Terminase
C2U38_RS24095	COG1802	Transcriptional regulator
C2U38_RS24120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C2U38_RS24145	COG5532	Uncharacterized conserved protein (DUF2303)
C2U38_RS24150	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C2U38_RS24205	COG0735	belongs to the Fur family
C2U38_RS24210	COG3237	CsbD-like
C2U38_RS24215	COG0534	Mate efflux family protein
C2U38_RS24225	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C2U38_RS24260	COG2182	Extracellular solute-binding protein
C2U38_RS24280	COG3223	Belongs to the PsiE family
C2U38_RS24285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C2U38_RS24290	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C2U38_RS24315	COG0527	aspartate kinase activity
C2U38_RS24330	COG1187	pseudouridine synthase activity
C2U38_RS24335	COG4977	sequence-specific DNA binding
C2U38_RS24355	COG1410	methionine synthase
C2U38_RS24355	COG0646	methionine synthase
C2U38_RS24375	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C2U38_RS24420	COG0151	Belongs to the GarS family
C2U38_RS24430	COG4191	Histidine kinase
C2U38_RS24485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2U38_RS24490	COG2104	thiamine diphosphate biosynthetic process
C2U38_RS24505	COG1278	Cold shock
C2U38_RS24515	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2U38_RS24555	COG0250	Participates in transcription elongation, termination and antitermination
C2U38_RS24600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C2U38_RS24660	COG0583	DNA-binding transcription factor activity
C2U38_RS24670	COG3979	chitinase
C2U38_RS24705	COG2207	Transcriptional regulator
C2U38_RS24710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS24715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2U38_RS24720	COG1882	Formate acetyltransferase
C2U38_RS24725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS24730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS24735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2U38_RS24735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS24735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS24745	COG0371	Dehydrogenase
C2U38_RS24755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C2U38_RS24760	COG0583	DNA-binding transcription factor activity
C2U38_RS24770	COG0737	Belongs to the 5'-nucleotidase family
C2U38_RS24780	COG0527	aspartate kinase activity
C2U38_RS24780	COG0460	homoserine dehydrogenase
C2U38_RS24785	COG0626	cystathionine gamma-synthase activity
C2U38_RS24795	COG2211	Major facilitator Superfamily
C2U38_RS24810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C2U38_RS24815	COG1609	Transcriptional regulator
C2U38_RS24825	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C2U38_RS24840	COG1575	Belongs to the MenA family. Type 1 subfamily
C2U38_RS24860	COG0582	viral genome integration into host DNA
C2U38_RS24880	COG3074	FtsZ-dependent cytokinesis
C2U38_RS24885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C2U38_RS24895	COG1494	fructose-1,6-bisphosphatase
C2U38_RS24905	COG3152	Membrane
C2U38_RS24930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C2U38_RS24945	COG3678	ATP-independent chaperone mediated protein folding
C2U38_RS24950	COG0745	RESPONSE REGULATOR receiver
C2U38_RS24955	COG2205	protein histidine kinase activity
C2U38_RS24960	COG2271	Major facilitator Superfamily
C2U38_RS24965	COG1082	Xylose isomerase domain protein TIM barrel
C2U38_RS24970	COG2188	Transcriptional regulator
C2U38_RS24975	COG2258	MOSC domain
C2U38_RS24980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2U38_RS25025	COG1454	alcohol dehydrogenase
C2U38_RS25045	COG3039	Transposase
C2U38_RS25055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C2U38_RS25065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS25070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS25070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS25075	COG1363	Peptidase, m42
C2U38_RS25080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS25080	COG3711	transcriptional antiterminator
C2U38_RS25100	COG0243	molybdopterin cofactor binding
C2U38_RS25100	COG3383	formate dehydrogenase (NAD+) activity
C2U38_RS25105	COG3383	formate dehydrogenase (NAD+) activity
C2U38_RS25105	COG0243	molybdopterin cofactor binding
C2U38_RS25110	COG0437	4 iron, 4 sulfur cluster binding
C2U38_RS25115	COG2864	formate dehydrogenase
C2U38_RS25130	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C2U38_RS25135	COG0657	acetylesterase activity
C2U38_RS25140	COG3609	addiction module antidote protein, CC2985 family
C2U38_RS25150	COG0456	acetyltransferase
C2U38_RS25155	COG1490	D-aminoacyl-tRNA deacylase activity
C2U38_RS25180	COG1349	DNA-binding transcription factor activity
C2U38_RS25185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS25195	COG3684	Belongs to the aldolase LacD family
C2U38_RS25205	COG2017	converts alpha-aldose to the beta-anomer
C2U38_RS25210	COG1501	Belongs to the glycosyl hydrolase 31 family
C2U38_RS25250	COG3852	Histidine kinase
C2U38_RS25255	COG2204	response regulator
C2U38_RS25265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2U38_RS25290	COG0204	Acyl-transferase
C2U38_RS25305	COG3084	Protein conserved in bacteria
C2U38_RS25310	COG0746	molybdenum cofactor guanylyltransferase activity
C2U38_RS25315	COG1763	Mo-molybdopterin cofactor biosynthetic process
C2U38_RS25355	COG1739	Uncharacterized protein family UPF0029
C2U38_RS25375	COG1609	Transcriptional regulator
C2U38_RS25380	COG1940	carbohydrate kinase activity
C2U38_RS25390	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C2U38_RS25405	COG0805	protein transport
C2U38_RS25450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2U38_RS25455	COG0583	DNA-binding transcription factor activity
C2U38_RS25460	COG0697	spore germination
C2U38_RS25465	COG0561	phosphatase activity
C2U38_RS25470	COG2267	carboxylic ester hydrolase activity
C2U38_RS25475	COG1280	lysine exporter protein (LysE YggA)
C2U38_RS25480	COG1280	lysine exporter protein (LysE YggA)
C2U38_RS25515	COG1011	Hydrolase
C2U38_RS25560	COG2959	enzyme of heme biosynthesis
C2U38_RS25565	COG3071	HemY protein
C2U38_RS25610	COG2244	polysaccharide biosynthetic process
C2U38_RS25615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2U38_RS25620	COG0456	acetyltransferase
C2U38_RS25625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C2U38_RS25630	COG1088	dTDP-glucose 4,6-dehydratase activity
C2U38_RS25635	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C2U38_RS25650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2U38_RS25660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C2U38_RS25670	COG3118	belongs to the thioredoxin family
C2U38_RS25690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2U38_RS25710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2U38_RS25720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2U38_RS25725	COG3978	acetolactate synthase activity
C2U38_RS25745	COG3085	chromosome segregation
C2U38_RS25785	COG2186	Transcriptional regulator
C2U38_RS25790	COG0477	Major facilitator Superfamily
C2U38_RS25795	COG1609	Transcriptional regulator
C2U38_RS25800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2U38_RS25805	COG1879	ABC-type sugar transport system periplasmic component
C2U38_RS25810	COG1172	Belongs to the binding-protein-dependent transport system permease family
C2U38_RS25820	COG1869	D-ribose catabolic process
C2U38_RS25845	COG1522	sequence-specific DNA binding
C2U38_RS25850	COG0716	FMN binding
C2U38_RS25865	COG3312	ion transport
C2U38_RS25890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C2U38_RS25900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C2U38_RS25905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C2U38_RS25920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2U38_RS25930	COG0573	inorganic phosphate transmembrane transporter activity
C2U38_RS25935	COG0581	inorganic phosphate transmembrane transporter activity
C2U38_RS25945	COG0704	Plays a role in the regulation of phosphate uptake
C2U38_RS25950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2U38_RS25955	COG2252	PERMEase
C2U38_RS25960	COG0431	NADPH-dependent FMN reductase
C2U38_RS25965	COG2091	lysine biosynthetic process via aminoadipic acid
C2U38_RS26000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C2U38_RS26010	COG0592	DNA-directed DNA polymerase activity
C2U38_RS26025	COG0561	phosphatase activity
C2U38_RS26035	COG0823	Involved in the tonB-independent uptake of proteins
C2U38_RS26040	COG5645	(Lipo)protein
C2U38_RS26060	COG2188	Transcriptional regulator
C2U38_RS26075	COG2207	Transcriptional regulator
C2U38_RS26080	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2U38_RS26085	COG3119	arylsulfatase activity
C2U38_RS26090	COG2149	membrane
C2U38_RS26100	COG0641	radical SAM
C2U38_RS26110	COG2610	gluconate transmembrane transporter activity
C2U38_RS26115	COG0583	DNA-binding transcription factor activity
C2U38_RS26125	COG2814	Major facilitator Superfamily
C2U38_RS26150	COG0028	Belongs to the TPP enzyme family
C2U38_RS26155	COG0440	acetolactate synthase activity
C2U38_RS26160	COG1349	DNA-binding transcription factor activity
C2U38_RS26170	COG0738	Major facilitator superfamily
C2U38_RS26185	COG2197	response regulator
C2U38_RS26205	COG2826	transposase and inactivated derivatives, IS30 family
C2U38_RS26275	COG1136	(ABC) transporter
C2U38_RS26285	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C2U38_RS26300	COG0582	viral genome integration into host DNA
C2U38_RS26310	COG2211	Major facilitator Superfamily
C2U38_RS26315	COG1501	Belongs to the glycosyl hydrolase 31 family
C2U38_RS26320	COG3711	transcriptional antiterminator
C2U38_RS26325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS26325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS26325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS26330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS26335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS26335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2U38_RS26345	COG0191	fructose-bisphosphate aldolase activity
C2U38_RS26355	COG2982	Protein involved in outer membrane biogenesis
C2U38_RS26360	COG2233	PERMEase
C2U38_RS26365	COG0786	glutamate:sodium symporter activity
C2U38_RS26370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C2U38_RS26375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2U38_RS26380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2U38_RS26400	COG2860	membrane
C2U38_RS26405	COG1561	YicC-like family, N-terminal region
C2U38_RS26435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2U38_RS26450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C2U38_RS26465	COG1519	Transferase
C2U38_RS26470	COG0859	PFAM glycosyl transferase family 9
C2U38_RS26475	COG0438	transferase activity, transferring glycosyl groups
C2U38_RS26480	COG0515	serine threonine protein kinase
C2U38_RS26505	COG0859	PFAM glycosyl transferase family 9
C2U38_RS26510	COG0859	PFAM glycosyl transferase family 9
C2U38_RS26525	COG0156	8-amino-7-oxononanoate synthase activity
C2U38_RS26540	COG1216	Glycosyl transferase, family 2
C2U38_RS26545	COG2861	carbohydrate metabolic process
C2U38_RS26550	COG4942	peptidase
C2U38_RS26560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2U38_RS26565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C2U38_RS26585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C2U38_RS26590	COG2271	Major facilitator Superfamily
C2U38_RS26600	COG2186	Transcriptional regulator
C2U38_RS26620	COG3722	fumarate hydratase activity
C2U38_RS26635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2U38_RS26635	COG2213	PTS system mannitol-specific
C2U38_RS26645	COG1566	PFAM secretion protein HlyD family protein
C2U38_RS26650	COG0625	glutathione transferase activity
C2U38_RS26660	COG3276	selenocysteine insertion sequence binding
C2U38_RS26665	COG1454	alcohol dehydrogenase
C2U38_RS26670	COG1012	belongs to the aldehyde dehydrogenase family
C2U38_RS26680	COG1566	PFAM secretion protein HlyD family protein
C2U38_RS26685	COG0583	DNA-binding transcription factor activity
C2U38_RS26690	COG3713	MltA-interacting MipA family protein
C2U38_RS26700	COG0235	Class ii aldolase
C2U38_RS26705	COG3623	hexulose-6-phosphate isomerase
C2U38_RS26710	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C2U38_RS26715	COG1070	Carbohydrate kinase
C2U38_RS26720	COG2271	Major facilitator Superfamily
C2U38_RS26730	COG2731	YhcH YjgK YiaL family protein
C2U38_RS26740	COG1414	Transcriptional regulator
C2U38_RS26745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C2U38_RS26750	COG3977	Valine--pyruvate aminotransferase
C2U38_RS26830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C2U38_RS26960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2U38_RS27075	COG0659	secondary active sulfate transmembrane transporter activity
C2U38_RS27080	COG0589	response to stress
C2U38_RS27085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2U38_RS27090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS27130	COG0589	response to stress
C2U38_RS27165	COG1309	transcriptional regulator
C2U38_RS27180	COG1136	(ABC) transporter
C2U38_RS27195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS27210	COG1342	Belongs to the UPF0251 family
C2U38_RS27225	COG0783	Belongs to the Dps family
C2U38_RS27230	COG0640	Transcriptional regulator
C2U38_RS27235	COG0446	pyridine nucleotide-disulphide oxidoreductase
C2U38_RS27270	COG3039	Transposase
C2U38_RS27285	COG1528	Iron-storage protein
C2U38_RS27300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS27310	COG4644	lycopene metabolic process
C2U38_RS27340	COG0625	glutathione transferase activity
C2U38_RS27345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C2U38_RS27355	COG0583	DNA-binding transcription factor activity
C2U38_RS27365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C2U38_RS27380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C2U38_RS27400	COG1846	Transcriptional regulator
C2U38_RS27405	COG0583	DNA-binding transcription factor activity
C2U38_RS27415	COG2948	multi-organism process
C2U38_RS27470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2U38_RS27660	COG3039	Transposase
C2U38_RS27790	COG3039	Transposase
C2U38_RS27800	COG3039	Transposase
C2U38_RS27820	COG5642	Protein of unknown function (DUF2384)
C2U38_RS27825	COG5654	RES domain protein
C2U38_RS27885	COG0058	SHG alpha-glucan phosphorylase activity
C2U38_RS27890	COG0033	Phosphoglucomutase
C2U38_RS27930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2U38_RS27960	COG3039	Transposase
C2U38_RS27985	COG4974	Belongs to the 'phage' integrase family
C2U38_RS27990	COG3385	transposase activity
C2U38_RS28040	COG2963	transposase activity
C2U38_RS28075	COG3706	GGDEF domain
C2U38_RS28105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C2U38_RS28110	COG1127	ABC transporter
C2U38_RS28140	COG1662	PFAM IS1 transposase
C2U38_RS28140	COG3677	Transposase
C2U38_RS28150	COG1662	PFAM IS1 transposase
C2U38_RS28155	COG2951	lytic endotransglycosylase activity
C2U38_RS28175	COG2894	cell division
C2U38_RS28185	COG3039	Transposase
C2U38_RS28195	COG3093	addiction module antidote protein HigA
C2U38_RS28250	COG2610	gluconate transmembrane transporter activity
C2U38_RS28255	COG4680	protein conserved in bacteria
C2U38_RS28275	COG0640	Transcriptional regulator
C2U38_RS28280	COG0783	Belongs to the Dps family
C2U38_RS28355	COG1196	nuclear chromosome segregation
C2U38_RS28370	COG2801	Transposase and inactivated derivatives
C2U38_RS28390	COG2223	nitrite transmembrane transporter activity
C2U38_RS28400	COG1609	Transcriptional regulator