locus-tag	class	description
I6H86_RS00005	COG0582	viral genome integration into host DNA
I6H86_RS00015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS00020	COG0735	belongs to the Fur family
I6H86_RS00030	COG0523	cobalamin synthesis protein
I6H86_RS00055	COG0523	cobalamin synthesis protein
I6H86_RS00085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS00090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS00095	COG1121	(ABC) transporter
I6H86_RS00100	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6H86_RS00105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
I6H86_RS00115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
I6H86_RS00145	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6H86_RS00150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS00155	COG1121	(ABC) transporter
I6H86_RS00165	COG0582	viral genome integration into host DNA
I6H86_RS00180	COG0583	DNA-binding transcription factor activity
I6H86_RS00275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I6H86_RS00280	COG1418	mRNA catabolic process
I6H86_RS00285	COG0270	DNA (cytosine-5-)-methyltransferase activity
I6H86_RS00290	COG3727	T/G mismatch-specific endonuclease activity
I6H86_RS00295	COG0697	spore germination
I6H86_RS00300	COG2354	Protein conserved in bacteria
I6H86_RS00305	COG5475	Uncharacterized small protein (DUF2158)
I6H86_RS00325	COG2197	response regulator
I6H86_RS00340	COG1338	Plays a role in the flagellum-specific transport system
I6H86_RS00360	COG1580	Controls the rotational direction of flagella during chemotaxis
I6H86_RS00400	COG0425	Belongs to the sulfur carrier protein TusA family
I6H86_RS00415	COG0366	Alpha amylase catalytic
I6H86_RS00435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I6H86_RS00440	COG0500	methyltransferase
I6H86_RS00480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS00490	COG0765	amino acid transport
I6H86_RS00495	COG1126	abc transporter atp-binding protein
I6H86_RS00500	COG2197	response regulator
I6H86_RS00510	COG2197	response regulator
I6H86_RS00540	COG3012	SEC-C Motif Domain Protein
I6H86_RS00540	COG3318	Belongs to the UPF0149 family
I6H86_RS00545	COG0814	amino acid
I6H86_RS00555	COG1528	Iron-storage protein
I6H86_RS00575	COG1528	Iron-storage protein
I6H86_RS00585	COG1879	ABC-type sugar transport system periplasmic component
I6H86_RS00590	COG1129	ABC transporter
I6H86_RS00595	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS00645	COG1301	dicarboxylic acid transport
I6H86_RS00655	COG0840	transmembrane signaling receptor activity
I6H86_RS00670	COG0745	RESPONSE REGULATOR receiver
I6H86_RS00680	COG3539	Fimbrial protein
I6H86_RS00685	COG3188	usher protein
I6H86_RS00690	COG3121	Chaperone
I6H86_RS00695	COG3539	Fimbrial protein
I6H86_RS00720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
I6H86_RS00735	COG3102	Protein conserved in bacteria
I6H86_RS00755	COG3788	relative of glutathione S-transferase, MAPEG superfamily
I6H86_RS00760	COG1801	Protein of unknown function DUF72
I6H86_RS00765	COG1335	isochorismatase
I6H86_RS00775	COG0494	nUDIX hydrolase
I6H86_RS00800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS00810	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
I6H86_RS00815	COG0739	heme binding
I6H86_RS00820	COG1560	Kdo2-lipid A biosynthetic process
I6H86_RS00830	COG1737	Transcriptional regulator
I6H86_RS00835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
I6H86_RS00840	COG0129	dihydroxy-acid dehydratase activity
I6H86_RS00845	COG0800	Aldolase
I6H86_RS00855	COG3141	response to X-ray
I6H86_RS00865	COG2979	Protein of unknown function (DUF533)
I6H86_RS00870	COG1770	oligopeptidase
I6H86_RS00875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6H86_RS00880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6H86_RS00890	COG2372	response to copper ion
I6H86_RS00895	COG1276	copper resistance
I6H86_RS00910	COG4771	TonB-dependent receptor
I6H86_RS00915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
I6H86_RS00935	COG3008	intermembrane lipid transfer
I6H86_RS00940	COG2995	paraquat-inducible protein a
I6H86_RS00945	COG1956	GAF domain-containing protein
I6H86_RS00965	COG2814	Major facilitator Superfamily
I6H86_RS00970	COG1414	Transcriptional regulator
I6H86_RS01000	COG0768	penicillin binding
I6H86_RS01005	COG2226	methyltransferase
I6H86_RS01020	COG3716	PTS system mannose fructose sorbose family IID component
I6H86_RS01025	COG3715	PTS system
I6H86_RS01030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS01030	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS01035	COG1253	flavin adenine dinucleotide binding
I6H86_RS01040	COG2200	EAL domain
I6H86_RS01045	COG1760	l-serine dehydratase
I6H86_RS01065	COG0251	oxidation-reduction process
I6H86_RS01070	COG1199	ATP-dependent helicase activity
I6H86_RS01075	COG1214	PFAM Peptidase M22, glycoprotease
I6H86_RS01080	COG3065	identical protein binding
I6H86_RS01085	COG0318	PFAM AMP-dependent synthetase and ligase
I6H86_RS01090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
I6H86_RS01095	COG0473	3-isopropylmalate dehydrogenase activity
I6H86_RS01100	COG0583	DNA-binding transcription factor activity
I6H86_RS01105	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
I6H86_RS01110	COG2894	cell division
I6H86_RS01125	COG0179	Fumarylacetoacetate (FAA) hydrolase
I6H86_RS01155	COG2719	SpoVR family
I6H86_RS01165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I6H86_RS01175	COG1619	proteins homologs of microcin C7 resistance protein MccF
I6H86_RS01185	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
I6H86_RS01195	COG4774	siderophore transport
I6H86_RS01205	COG0157	Belongs to the NadC ModD family
I6H86_RS01215	COG1120	ATPase activity
I6H86_RS01220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS01225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6H86_RS01240	COG1461	Dihydroxyacetone kinase
I6H86_RS01245	COG2376	Dihydroxyacetone kinase
I6H86_RS01250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I6H86_RS01290	COG0583	DNA-binding transcription factor activity
I6H86_RS01295	COG0243	molybdopterin cofactor binding
I6H86_RS01300	COG1271	oxidase subunit
I6H86_RS01305	COG1294	oxidase, subunit
I6H86_RS01320	COG3781	membrane
I6H86_RS01345	COG0454	-acetyltransferase
I6H86_RS01355	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I6H86_RS01360	COG0456	acetyltransferase
I6H86_RS01365	COG4771	TonB-dependent receptor
I6H86_RS01370	COG1021	2,3-dihydroxybenzoate-AMP ligase
I6H86_RS01390	COG3433	isochorismatase activity
I6H86_RS01390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I6H86_RS01390	COG2226	methyltransferase
I6H86_RS01405	COG1132	(ABC) transporter
I6H86_RS01410	COG2814	Major facilitator Superfamily
I6H86_RS01415	COG1169	isochorismate synthase
I6H86_RS01430	COG0012	GTP binding
I6H86_RS01465	COG1120	ATPase activity
I6H86_RS01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS01485	COG0659	secondary active sulfate transmembrane transporter activity
I6H86_RS01515	COG2890	protein-(glutamine-N5) methyltransferase activity
I6H86_RS01535	COG0387	Pfam Sodium calcium exchanger
I6H86_RS01540	COG4572	Cation transport regulator
I6H86_RS01545	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
I6H86_RS01555	COG0840	transmembrane signaling receptor activity
I6H86_RS01560	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
I6H86_RS01565	COG3707	response regulator
I6H86_RS01570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I6H86_RS01575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I6H86_RS01580	COG1116	anion transmembrane transporter activity
I6H86_RS01585	COG2146	nitrite reductase [NAD(P)H] activity
I6H86_RS01585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I6H86_RS01590	COG0243	molybdopterin cofactor binding
I6H86_RS01595	COG4932	domain protein
I6H86_RS01600	COG2197	response regulator
I6H86_RS01605	COG3850	Histidine kinase
I6H86_RS01610	COG2223	nitrite transmembrane transporter activity
I6H86_RS01615	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I6H86_RS01620	COG1140	nitrate reductase beta subunit
I6H86_RS01625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I6H86_RS01630	COG2181	nitrate reductase activity
I6H86_RS01680	COG0788	formyltetrahydrofolate deformylase activity
I6H86_RS01690	COG1752	Esterase of the alpha-beta hydrolase superfamily
I6H86_RS01695	COG0745	RESPONSE REGULATOR receiver
I6H86_RS01700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I6H86_RS01710	COG1435	thymidine kinase activity
I6H86_RS01715	COG1454	alcohol dehydrogenase
I6H86_RS01715	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS01720	COG2095	MarC family integral membrane protein
I6H86_RS01740	COG0444	Belongs to the ABC transporter superfamily
I6H86_RS01745	COG4608	Belongs to the ABC transporter superfamily
I6H86_RS01765	COG2350	Protein conserved in bacteria
I6H86_RS01790	COG3047	cAMP biosynthetic process
I6H86_RS01800	COG3706	GGDEF domain
I6H86_RS01840	COG0009	L-threonylcarbamoyladenylate synthase
I6H86_RS01845	COG1187	pseudouridine synthase activity
I6H86_RS01855	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS01860	COG0616	signal peptide processing
I6H86_RS01900	COG0671	phosphoesterase, PA-phosphatase related
I6H86_RS01905	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
I6H86_RS01910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
I6H86_RS01920	COG0023	Translation Initiation Factor
I6H86_RS01930	COG1349	DNA-binding transcription factor activity
I6H86_RS01940	COG5001	Diguanylate cyclase
I6H86_RS01950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6H86_RS01950	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6H86_RS01955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
I6H86_RS01965	COG3204	pilus organization
I6H86_RS02000	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
I6H86_RS02005	COG1842	Phage shock protein A
I6H86_RS02015	COG1983	PspC domain protein
I6H86_RS02025	COG3106	COG3106 Predicted ATPase
I6H86_RS02040	COG2211	Major facilitator Superfamily
I6H86_RS02065	COG4948	Mandelate Racemase Muconate Lactonizing
I6H86_RS02070	COG2866	Carboxypeptidase
I6H86_RS02075	COG4166	transmembrane transport
I6H86_RS02080	COG0668	transmembrane transport
I6H86_RS02085	COG3182	Iron-regulated membrane protein
I6H86_RS02105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I6H86_RS02110	COG2840	Smr protein MutS2
I6H86_RS02115	COG3706	GGDEF domain
I6H86_RS02125	COG0513	Belongs to the DEAD box helicase family
I6H86_RS02145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I6H86_RS02150	COG1013	pyruvate-flavodoxin oxidoreductase activity
I6H86_RS02150	COG0674	pyruvate-flavodoxin oxidoreductase activity
I6H86_RS02150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
I6H86_RS02150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6H86_RS02155	COG3042	response to heat
I6H86_RS02160	COG3187	Heat shock protein
I6H86_RS02165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
I6H86_RS02185	COG2911	Protein conserved in bacteria
I6H86_RS02195	COG3784	Protein of unknown function (DUF1318)
I6H86_RS02200	COG0667	Aldo Keto reductase
I6H86_RS02210	COG1643	Atp-dependent helicase
I6H86_RS02215	COG0583	DNA-binding transcription factor activity
I6H86_RS02225	COG1538	Outer membrane efflux protein
I6H86_RS02240	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I6H86_RS02245	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS02250	COG0657	acetylesterase activity
I6H86_RS02250	COG2755	lipolytic protein G-D-S-L family
I6H86_RS02255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I6H86_RS02260	COG3038	cytochrome b561
I6H86_RS02275	COG0840	transmembrane signaling receptor activity
I6H86_RS02280	COG0583	DNA-binding transcription factor activity
I6H86_RS02285	COG1227	inorganic diphosphatase activity
I6H86_RS02290	COG5383	Protein conserved in bacteria
I6H86_RS02295	COG2272	Belongs to the type-B carboxylesterase lipase family
I6H86_RS02305	COG2841	Protein conserved in bacteria
I6H86_RS02310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6H86_RS02315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I6H86_RS02320	COG1275	C4-dicarboxylate transporter malic acid transport protein
I6H86_RS02325	COG0500	methyltransferase
I6H86_RS02335	COG0697	spore germination
I6H86_RS02345	COG3135	benzoate transporter
I6H86_RS02350	COG1396	sequence-specific DNA binding
I6H86_RS02355	COG0826	peptidase U32
I6H86_RS02360	COG1724	mRNA binding
I6H86_RS02365	COG1598	PFAM Uncharacterised protein family UPF0150
I6H86_RS02370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6H86_RS02405	COG0747	negative chemotaxis
I6H86_RS02415	COG3238	Protein conserved in bacteria
I6H86_RS02420	COG1247	-acetyltransferase
I6H86_RS02430	COG2130	NADP-dependent
I6H86_RS02435	COG4772	TonB-dependent receptor
I6H86_RS02450	COG0625	glutathione transferase activity
I6H86_RS02455	COG5001	Diguanylate cyclase
I6H86_RS02455	COG4251	negative regulation of phosphorylation
I6H86_RS02455	COG3706	GGDEF domain
I6H86_RS02455	COG2203	Gaf domain
I6H86_RS02460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
I6H86_RS02465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
I6H86_RS02470	COG2181	nitrate reductase activity
I6H86_RS02475	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
I6H86_RS02480	COG1140	nitrate reductase beta subunit
I6H86_RS02485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
I6H86_RS02495	COG1309	transcriptional regulator
I6H86_RS02525	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS02530	COG2864	formate dehydrogenase
I6H86_RS02545	COG1764	response to oxidative stress
I6H86_RS02550	COG4608	Belongs to the ABC transporter superfamily
I6H86_RS02555	COG0444	Belongs to the ABC transporter superfamily
I6H86_RS02560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6H86_RS02565	COG0601	transmembrane transport
I6H86_RS02570	COG0747	negative chemotaxis
I6H86_RS02575	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
I6H86_RS02585	COG0840	transmembrane signaling receptor activity
I6H86_RS02600	COG1649	PFAM Uncharacterised BCR, COG1649
I6H86_RS02605	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
I6H86_RS02610	COG1193	negative regulation of DNA recombination
I6H86_RS02615	COG0148	phosphopyruvate hydratase activity
I6H86_RS02635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6H86_RS02665	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS02670	COG0583	DNA-binding transcription factor activity
I6H86_RS02675	COG0039	L-malate dehydrogenase activity
I6H86_RS02690	COG1846	Transcriptional regulator
I6H86_RS02705	COG0697	spore germination
I6H86_RS02710	COG2814	Major facilitator Superfamily
I6H86_RS02740	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I6H86_RS02750	COG3706	GGDEF domain
I6H86_RS02765	COG4221	oxidoreductase activity
I6H86_RS02770	COG1802	Transcriptional regulator
I6H86_RS02775	COG0246	Mannitol dehydrogenase
I6H86_RS02780	COG0477	Major facilitator Superfamily
I6H86_RS02785	COG1063	alcohol dehydrogenase
I6H86_RS02790	COG4948	Mandelate Racemase Muconate Lactonizing
I6H86_RS02805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6H86_RS02820	COG0243	molybdopterin cofactor binding
I6H86_RS02825	COG0243	molybdopterin cofactor binding
I6H86_RS02830	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS02835	COG3302	dmso reductase anchor subunit
I6H86_RS02840	COG3381	protein complex oligomerization
I6H86_RS02870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
I6H86_RS02875	COG1940	carbohydrate kinase activity
I6H86_RS02880	COG0583	DNA-binding transcription factor activity
I6H86_RS02885	COG2814	Major facilitator Superfamily
I6H86_RS02895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
I6H86_RS02905	COG3591	Belongs to the peptidase S1B family
I6H86_RS02920	COG0628	permease
I6H86_RS02925	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
I6H86_RS02930	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
I6H86_RS02940	COG0531	amino acid
I6H86_RS02950	COG3136	membrane protein required for alginate biosynthesis
I6H86_RS02955	COG0745	RESPONSE REGULATOR receiver
I6H86_RS02960	COG2205	protein histidine kinase activity
I6H86_RS02970	COG0114	fumarate hydratase activity
I6H86_RS02975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS02975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS02985	COG5339	Protein conserved in bacteria
I6H86_RS02990	COG1609	Transcriptional regulator
I6H86_RS02995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS02995	COG1263	PTS System
I6H86_RS03000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I6H86_RS03010	COG0673	inositol 2-dehydrogenase activity
I6H86_RS03060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I6H86_RS03070	COG0625	glutathione transferase activity
I6H86_RS03075	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
I6H86_RS03090	COG3895	Periplasmic Protein
I6H86_RS03115	COG1566	PFAM secretion protein HlyD family protein
I6H86_RS03130	COG4989	oxidoreductase activity
I6H86_RS03135	COG3313	Fe-S protein
I6H86_RS03140	COG1309	transcriptional regulator
I6H86_RS03145	COG1902	pentaerythritol trinitrate reductase activity
I6H86_RS03150	COG0346	lactoylglutathione lyase activity
I6H86_RS03160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
I6H86_RS03165	COG0791	NLP P60 protein
I6H86_RS03170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I6H86_RS03175	COG2814	Major facilitator Superfamily
I6H86_RS03190	COG0583	DNA-binding transcription factor activity
I6H86_RS03195	COG2814	Major facilitator Superfamily
I6H86_RS03200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
I6H86_RS03205	COG0307	riboflavin synthase, alpha
I6H86_RS03225	COG4771	TonB-dependent receptor
I6H86_RS03230	COG2819	hydrolase of the alpha beta superfamily
I6H86_RS03250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS03260	COG0765	amino acid transport
I6H86_RS03265	COG0765	amino acid transport
I6H86_RS03275	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
I6H86_RS03280	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS03290	COG2414	aldehyde ferredoxin oxidoreductase
I6H86_RS03295	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS03305	COG1464	Belongs to the NlpA lipoprotein family
I6H86_RS03310	COG2011	ABC-type metal ion transport system permease component
I6H86_RS03325	COG0626	cystathionine gamma-synthase activity
I6H86_RS03340	COG1376	ErfK ybiS ycfS ynhG family protein
I6H86_RS03355	COG0719	Fe-S assembly protein
I6H86_RS03360	COG0396	ATPase activity
I6H86_RS03365	COG0719	Fe-S assembly protein
I6H86_RS03370	COG0316	Belongs to the HesB IscA family
I6H86_RS03390	COG2050	protein possibly involved in aromatic compounds catabolism
I6H86_RS03395	COG0247	lactate metabolic process
I6H86_RS03395	COG0277	FAD linked oxidase domain protein
I6H86_RS03400	COG0628	permease
I6H86_RS03410	COG0574	Belongs to the PEP-utilizing enzyme family
I6H86_RS03410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6H86_RS03425	COG4256	Hemin uptake protein
I6H86_RS03445	COG0791	NLP P60 protein
I6H86_RS03455	COG0386	Belongs to the glutathione peroxidase family
I6H86_RS03515	COG3137	Salt-induced outer membrane protein
I6H86_RS03520	COG1105	Belongs to the carbohydrate kinase PfkB family
I6H86_RS03530	COG3001	Fructosamine kinase
I6H86_RS03540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6H86_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS03550	COG1988	membrane-bound metal-dependent
I6H86_RS03555	COG1823	symporter activity
I6H86_RS03570	COG1486	melibiose metabolic process
I6H86_RS03575	COG2169	Transcriptional regulator
I6H86_RS03575	COG1917	Cupin 2, conserved barrel domain protein
I6H86_RS03580	COG1447	Phosphotransferase system cellobiose-specific component IIA
I6H86_RS03585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I6H86_RS03590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I6H86_RS03595	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6H86_RS03610	COG3678	ATP-independent chaperone mediated protein folding
I6H86_RS03640	COG0708	Exodeoxyribonuclease III
I6H86_RS03650	COG4134	Bacterial extracellular solute-binding protein
I6H86_RS03655	COG4135	transport system, permease component
I6H86_RS03660	COG4136	ATPase activity
I6H86_RS03665	COG2897	thiosulfate sulfurtransferase activity
I6H86_RS03670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I6H86_RS03675	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6H86_RS03680	COG0494	nUDIX hydrolase
I6H86_RS03695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I6H86_RS03705	COG0778	Nitroreductase
I6H86_RS03710	COG0616	signal peptide processing
I6H86_RS03715	COG0252	asparaginase activity
I6H86_RS03720	COG1335	isochorismatase
I6H86_RS03725	COG3139	Protein of unknown function (DUF1315)
I6H86_RS03745	COG3713	MltA-interacting MipA family protein
I6H86_RS03750	COG2766	serine protein kinase
I6H86_RS03760	COG2226	methyltransferase
I6H86_RS03765	COG2199	diguanylate cyclase activity
I6H86_RS03770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6H86_RS03785	COG2207	Transcriptional regulator
I6H86_RS03790	COG2807	transmembrane transport
I6H86_RS03795	COG0504	CTP synthase activity
I6H86_RS03800	COG3189	MarR family transcriptional regulator
I6H86_RS03805	COG3042	response to heat
I6H86_RS03815	COG2261	transglycosylase associated protein
I6H86_RS03820	COG3383	formate dehydrogenase (NAD+) activity
I6H86_RS03835	COG3615	Tellurite resistance protein tehB
I6H86_RS03845	COG3443	Belongs to the bacterial solute-binding protein 9 family
I6H86_RS03850	COG0243	molybdopterin cofactor binding
I6H86_RS03855	COG3005	denitrification pathway
I6H86_RS03865	COG1560	Kdo2-lipid A biosynthetic process
I6H86_RS03870	COG0538	isocitrate dehydrogenase activity
I6H86_RS03875	COG1187	pseudouridine synthase activity
I6H86_RS03895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I6H86_RS03900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I6H86_RS03910	COG2246	polysaccharide biosynthetic process
I6H86_RS03915	COG0463	Glycosyl transferase, family 2
I6H86_RS03955	COG1196	nuclear chromosome segregation
I6H86_RS04045	COG3772	lysozyme
I6H86_RS04075	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
I6H86_RS04120	COG2226	methyltransferase
I6H86_RS04135	COG1349	DNA-binding transcription factor activity
I6H86_RS04150	COG1846	Transcriptional regulator
I6H86_RS04205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6H86_RS04225	COG0582	viral genome integration into host DNA
I6H86_RS04240	COG2850	peptidyl-arginine hydroxylation
I6H86_RS04260	COG1177	transmembrane transport
I6H86_RS04270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
I6H86_RS04280	COG4591	ABC-type transport system involved in lipoprotein release permease component
I6H86_RS04285	COG1136	(ABC) transporter
I6H86_RS04290	COG4591	ABC-type transport system involved in lipoprotein release permease component
I6H86_RS04295	COG4763	Acyl-transferase
I6H86_RS04300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I6H86_RS04305	COG1388	LysM domain
I6H86_RS04305	COG1376	ErfK ybiS ycfS ynhG family protein
I6H86_RS04315	COG1309	transcriptional regulator
I6H86_RS04320	COG3134	Outer membrane lipoprotein
I6H86_RS04325	COG1252	NADH dehydrogenase
I6H86_RS04350	COG5633	Lipoprotein
I6H86_RS04355	COG0537	adenosine 5'-monophosphoramidase activity
I6H86_RS04370	COG0084	hydrolase, TatD family'
I6H86_RS04375	COG0470	DNA polymerase III
I6H86_RS04385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I6H86_RS04390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I6H86_RS04395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6H86_RS04410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I6H86_RS04445	COG1530	ribonuclease E activity
I6H86_RS04455	COG1256	bacterial-type flagellum assembly
I6H86_RS04475	COG4786	Flagellar basal body rod
I6H86_RS04480	COG4787	bacterial-type flagellum-dependent cell motility
I6H86_RS04490	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
I6H86_RS04495	COG1558	bacterial-type flagellum-dependent cell motility
I6H86_RS04535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6H86_RS04545	COG2999	glutathione oxidoreductase activity
I6H86_RS04580	COG3038	cytochrome b561
I6H86_RS04585	COG2353	YceI-like domain
I6H86_RS04595	COG1560	Kdo2-lipid A biosynthetic process
I6H86_RS04610	COG5645	(Lipo)protein
I6H86_RS04630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6H86_RS04685	COG3381	protein complex oligomerization
I6H86_RS04710	COG1702	phosphate starvation-inducible protein PhoH
I6H86_RS04725	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
I6H86_RS04725	COG0506	proline dehydrogenase activity
I6H86_RS04725	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
I6H86_RS04735	COG1309	transcriptional regulator
I6H86_RS04740	COG3729	General stress protein
I6H86_RS04770	COG1136	(ABC) transporter
I6H86_RS04770	COG0577	efflux transmembrane transporter activity
I6H86_RS04775	COG1136	(ABC) transporter
I6H86_RS04775	COG0577	efflux transmembrane transporter activity
I6H86_RS04780	COG0577	efflux transmembrane transporter activity
I6H86_RS04780	COG1136	(ABC) transporter
I6H86_RS04795	COG0672	)-iron permease
I6H86_RS04800	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
I6H86_RS04805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6H86_RS04810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
I6H86_RS04810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6H86_RS04815	COG4232	protein-disulfide reductase activity
I6H86_RS04835	COG3093	addiction module antidote protein HigA
I6H86_RS04840	COG3549	Plasmid maintenance system killer
I6H86_RS04845	COG0348	domain, Protein
I6H86_RS04855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I6H86_RS04870	COG2515	1-aminocyclopropane-1-carboxylate deaminase
I6H86_RS04875	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
I6H86_RS04885	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
I6H86_RS04940	COG0670	Belongs to the BI1 family
I6H86_RS04945	COG2920	part of a sulfur-relay system
I6H86_RS04965	COG1832	CoA-binding protein
I6H86_RS04980	COG0210	DNA helicase
I6H86_RS04985	COG3304	Inner membrane component domain
I6H86_RS04990	COG1289	transmembrane transporter activity
I6H86_RS04995	COG3070	regulator of competence-specific genes
I6H86_RS05005	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
I6H86_RS05005	COG2885	chlorophyll binding
I6H86_RS05015	COG1067	ATP-dependent peptidase activity
I6H86_RS05025	COG3130	regulation of translation
I6H86_RS05030	COG3009	Protein conserved in bacteria
I6H86_RS05035	COG3008	intermembrane lipid transfer
I6H86_RS05035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I6H86_RS05040	COG2995	paraquat-inducible protein a
I6H86_RS05045	COG0488	(ABC) transporter
I6H86_RS05055	COG0633	Ferredoxin
I6H86_RS05055	COG3217	Mosc domain protein beta barrel domain protein
I6H86_RS05070	COG0431	NADPH-dependent FMN reductase
I6H86_RS05075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I6H86_RS05085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I6H86_RS05095	COG0308	aminopeptidase N
I6H86_RS05120	COG1448	Aminotransferase
I6H86_RS05125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
I6H86_RS05130	COG3108	Peptidase M15
I6H86_RS05135	COG2989	Protein conserved in bacteria
I6H86_RS05145	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
I6H86_RS05155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
I6H86_RS05160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
I6H86_RS05165	COG3173	Aminoglycoside phosphotransferase
I6H86_RS05180	COG3214	Protein conserved in bacteria
I6H86_RS05195	COG0658	competence protein
I6H86_RS05195	COG2333	competence protein COMEC
I6H86_RS05205	COG0539	negative regulation of cytoplasmic translation
I6H86_RS05225	COG1944	ATP diphosphatase activity
I6H86_RS05230	COG2116	formate transmembrane transporter activity
I6H86_RS05235	COG1882	Formate acetyltransferase
I6H86_RS05240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6H86_RS05250	COG1335	isochorismatase
I6H86_RS05255	COG3302	dmso reductase anchor subunit
I6H86_RS05260	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS05265	COG0243	molybdopterin cofactor binding
I6H86_RS05275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I6H86_RS05295	COG0492	ferredoxin-NADP+ reductase activity
I6H86_RS05300	COG4988	ABC transporter
I6H86_RS05305	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
I6H86_RS05325	COG0583	DNA-binding transcription factor activity
I6H86_RS05335	COG1335	isochorismatase
I6H86_RS05350	COG0542	response to heat
I6H86_RS05360	COG1278	Cold shock
I6H86_RS05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS05375	COG3593	DNA synthesis involved in DNA repair
I6H86_RS05385	COG2431	L-lysine efflux transmembrane transporter activity
I6H86_RS05395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I6H86_RS05405	COG0028	Belongs to the TPP enzyme family
I6H86_RS05410	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
I6H86_RS05415	COG0702	epimerase
I6H86_RS05420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6H86_RS05425	COG3397	chitin binding
I6H86_RS05440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
I6H86_RS05465	COG2165	general secretion pathway protein
I6H86_RS05475	COG2165	general secretion pathway protein
I6H86_RS05485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I6H86_RS05490	COG1450	Type ii and iii secretion system protein
I6H86_RS05515	COG3023	N-Acetylmuramoyl-L-alanine amidase
I6H86_RS05530	COG1126	abc transporter atp-binding protein
I6H86_RS05535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS05540	COG4215	(ABC) transporter
I6H86_RS05545	COG4160	amino acid transport
I6H86_RS05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS05555	COG5002	protein histidine kinase activity
I6H86_RS05560	COG0745	RESPONSE REGULATOR receiver
I6H86_RS05575	COG1177	transmembrane transport
I6H86_RS05580	COG1176	ABC-type spermidine putrescine transport system, permease component I
I6H86_RS05585	COG3842	ATPase activity
I6H86_RS05590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
I6H86_RS05630	COG3226	Transcriptional regulator
I6H86_RS05635	COG0738	Major facilitator superfamily
I6H86_RS05640	COG0561	phosphatase activity
I6H86_RS05645	COG2814	Major facilitator Superfamily
I6H86_RS05650	COG0671	phosphoesterase, PA-phosphatase related
I6H86_RS05655	COG1349	DNA-binding transcription factor activity
I6H86_RS05660	COG1686	Belongs to the peptidase S11 family
I6H86_RS05665	COG0625	glutathione transferase activity
I6H86_RS05670	COG2133	pyrroloquinoline quinone binding
I6H86_RS05695	COG0747	negative chemotaxis
I6H86_RS05720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
I6H86_RS05725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6H86_RS05730	COG1882	Formate acetyltransferase
I6H86_RS05735	COG3157	Type VI secretion system effector, Hcp
I6H86_RS05750	COG0561	phosphatase activity
I6H86_RS05760	COG1609	Transcriptional regulator
I6H86_RS05765	COG2271	Major facilitator Superfamily
I6H86_RS05775	COG0488	(ABC) transporter
I6H86_RS05780	COG1376	ErfK ybiS ycfS ynhG family protein
I6H86_RS05785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
I6H86_RS05790	COG1321	iron dependent repressor
I6H86_RS05800	COG2194	sulfuric ester hydrolase activity
I6H86_RS05805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
I6H86_RS05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS05825	COG0765	amino acid transport
I6H86_RS05830	COG1126	abc transporter atp-binding protein
I6H86_RS05835	COG0668	transmembrane transport
I6H86_RS05850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I6H86_RS05860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
I6H86_RS05870	COG3121	Chaperone
I6H86_RS05895	COG0513	Belongs to the DEAD box helicase family
I6H86_RS05900	COG1309	transcriptional regulator
I6H86_RS05910	COG1131	(ABC) transporter
I6H86_RS05915	COG0842	Transport permease protein
I6H86_RS05920	COG0842	Transport permease protein
I6H86_RS05930	COG3568	Endonuclease Exonuclease Phosphatase
I6H86_RS05935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6H86_RS05940	COG0392	lysyltransferase activity
I6H86_RS05945	COG0670	Belongs to the BI1 family
I6H86_RS05950	COG0314	molybdopterin synthase activity
I6H86_RS05955	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
I6H86_RS05965	COG0521	Mo-molybdopterin cofactor biosynthetic process
I6H86_RS05985	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
I6H86_RS06010	COG1881	PFAM PEBP family protein
I6H86_RS06040	COG4677	pectinesterase activity
I6H86_RS06045	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I6H86_RS06050	COG0471	metal ion transport
I6H86_RS06055	COG2828	Protein conserved in bacteria
I6H86_RS06060	COG0583	DNA-binding transcription factor activity
I6H86_RS06070	COG0561	phosphatase activity
I6H86_RS06080	COG4149	molybdate abc transporter
I6H86_RS06085	COG0725	ABC transporter, periplasmic molybdate-binding protein
I6H86_RS06095	COG3585	molybdate ion transport
I6H86_RS06095	COG2005	Transcriptional regulator
I6H86_RS06100	COG1119	ATPase activity
I6H86_RS06105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I6H86_RS06120	COG2017	converts alpha-aldose to the beta-anomer
I6H86_RS06130	COG1120	ATPase activity
I6H86_RS06135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS06150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I6H86_RS06165	COG3201	nicotinamide mononucleotide transporter
I6H86_RS06200	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
I6H86_RS06205	COG2885	chlorophyll binding
I6H86_RS06215	COG3064	Membrane
I6H86_RS06220	COG0848	biopolymer transport protein
I6H86_RS06225	COG0811	peptide transport
I6H86_RS06230	COG0824	Thioesterase
I6H86_RS06235	COG3790	cyd operon protein YbgE
I6H86_RS06240	COG4890	Cyd operon protein YbgT
I6H86_RS06245	COG1294	oxidase, subunit
I6H86_RS06250	COG1271	oxidase subunit
I6H86_RS06255	COG0383	alpha-mannosidase activity
I6H86_RS06260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS06260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS06260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS06265	COG2188	Transcriptional regulator
I6H86_RS06270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
I6H86_RS06280	COG4865	methylaspartate mutase activity
I6H86_RS06285	COG3799	methylaspartate ammonia-lyase activity
I6H86_RS06300	COG1301	dicarboxylic acid transport
I6H86_RS06305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS06305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS06315	COG0583	DNA-binding transcription factor activity
I6H86_RS06320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6H86_RS06330	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6H86_RS06335	COG0567	Dehydrogenase, E1 component
I6H86_RS06345	COG1053	succinate dehydrogenase
I6H86_RS06350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
I6H86_RS06355	COG2009	succinate dehydrogenase
I6H86_RS06365	COG3157	Type VI secretion system effector, Hcp
I6H86_RS06390	COG3180	Ammonia monooxygenase
I6H86_RS06405	COG2211	Major facilitator Superfamily
I6H86_RS06415	COG1917	Cupin 2, conserved barrel domain protein
I6H86_RS06415	COG4977	sequence-specific DNA binding
I6H86_RS06445	COG1984	allophanate hydrolase subunit 2
I6H86_RS06450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
I6H86_RS06455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
I6H86_RS06490	COG2205	protein histidine kinase activity
I6H86_RS06495	COG0745	RESPONSE REGULATOR receiver
I6H86_RS06505	COG1982	Orn Lys Arg decarboxylase major
I6H86_RS06510	COG0531	amino acid
I6H86_RS06515	COG0033	Phosphoglucomutase
I6H86_RS06520	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
I6H86_RS06525	COG0596	Alpha beta hydrolase
I6H86_RS06540	COG0735	belongs to the Fur family
I6H86_RS06560	COG2190	(PTS) system
I6H86_RS06560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS06560	COG1263	PTS System
I6H86_RS06570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I6H86_RS06575	COG1846	Transcriptional regulator
I6H86_RS06575	COG1940	carbohydrate kinase activity
I6H86_RS06580	COG0647	UMP catabolic process
I6H86_RS06585	COG0367	asparagine synthase
I6H86_RS06625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6H86_RS06635	COG1702	phosphate starvation-inducible protein PhoH
I6H86_RS06645	COG4535	Mg2 and Co2 transporter CorC
I6H86_RS06660	COG0765	amino acid transport
I6H86_RS06665	COG0765	amino acid transport
I6H86_RS06670	COG1126	abc transporter atp-binding protein
I6H86_RS06680	COG2888	peptidyl-tyrosine sulfation
I6H86_RS06695	COG1466	dna polymerase III delta subunit
I6H86_RS06705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
I6H86_RS06715	COG0799	negative regulation of ribosome biogenesis
I6H86_RS06725	COG0768	penicillin binding
I6H86_RS06730	COG0772	Belongs to the SEDS family
I6H86_RS06735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I6H86_RS06740	COG1686	Belongs to the peptidase S11 family
I6H86_RS06755	COG0583	DNA-binding transcription factor activity
I6H86_RS06770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6H86_RS06790	COG3069	C4-dicarboxylate transmembrane transporter activity
I6H86_RS06795	COG4565	transcriptional regulatory protein
I6H86_RS06800	COG3290	protein histidine kinase activity
I6H86_RS06805	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
I6H86_RS06815	COG2301	Belongs to the HpcH HpaI aldolase family
I6H86_RS06820	COG3051	citrate lyase alpha subunit
I6H86_RS06835	COG0471	metal ion transport
I6H86_RS06840	COG3719	Belongs to the RNase T2 family
I6H86_RS06845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I6H86_RS06855	COG3634	alkyl hydroperoxide reductase activity
I6H86_RS06865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
I6H86_RS06870	COG0583	DNA-binding transcription factor activity
I6H86_RS06875	COG3969	phosphoadenosine phosphosulfate
I6H86_RS06880	COG1475	DNA binding
I6H86_RS06885	COG0436	Aminotransferase
I6H86_RS06890	COG0371	Dehydrogenase
I6H86_RS06895	COG2879	small protein
I6H86_RS06900	COG1966	Carbon starvation protein
I6H86_RS06910	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS06915	COG1535	isochorismatase
I6H86_RS06915	COG3433	isochorismatase activity
I6H86_RS06920	COG1021	2,3-dihydroxybenzoate-AMP ligase
I6H86_RS06925	COG1169	isochorismate synthase
I6H86_RS06930	COG4592	Periplasmic binding protein
I6H86_RS06940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS06945	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS06950	COG1120	ATPase activity
I6H86_RS06955	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
I6H86_RS06960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
I6H86_RS06960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
I6H86_RS06965	COG3251	PFAM MbtH domain protein
I6H86_RS06970	COG2382	esterase
I6H86_RS06975	COG4771	TonB-dependent receptor
I6H86_RS06980	COG2977	Belongs to the P-Pant transferase superfamily
I6H86_RS06985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I6H86_RS07020	COG4774	siderophore transport
I6H86_RS07040	COG2315	Protein conserved in bacteria
I6H86_RS07055	COG0477	Major facilitator Superfamily
I6H86_RS07060	COG0668	transmembrane transport
I6H86_RS07065	COG1609	Transcriptional regulator
I6H86_RS07080	COG2211	Major facilitator Superfamily
I6H86_RS07085	COG1113	amino acid transport
I6H86_RS07105	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6H86_RS07110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS07115	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS07120	COG1538	Outer membrane efflux protein
I6H86_RS07125	COG0745	RESPONSE REGULATOR receiver
I6H86_RS07130	COG5002	protein histidine kinase activity
I6H86_RS07195	COG2501	S4 domain
I6H86_RS07205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
I6H86_RS07215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I6H86_RS07220	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
I6H86_RS07230	COG2011	ABC-type metal ion transport system permease component
I6H86_RS07240	COG1464	Belongs to the NlpA lipoprotein family
I6H86_RS07250	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
I6H86_RS07255	COG4181	ATPase activity
I6H86_RS07260	COG2755	lipolytic protein G-D-S-L family
I6H86_RS07265	COG0300	oxidoreductase activity
I6H86_RS07270	COG3118	belongs to the thioredoxin family
I6H86_RS07275	COG0390	transport system, permease component
I6H86_RS07280	COG4619	ABC transporter
I6H86_RS07285	COG0330	HflC and HflK could
I6H86_RS07290	COG1585	Membrane protein implicated in regulation of membrane protease activity
I6H86_RS07300	COG4771	TonB-dependent receptor
I6H86_RS07305	COG4558	Periplasmic binding protein
I6H86_RS07315	COG3721	Heme iron utilization protein
I6H86_RS07325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS07335	COG0477	Major facilitator Superfamily
I6H86_RS07340	COG1609	Transcriptional regulator
I6H86_RS07350	COG1285	pathogenesis
I6H86_RS07355	COG2217	Heavy metal translocating P-type atpase
I6H86_RS07360	COG3735	TraB family
I6H86_RS07365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6H86_RS07375	COG2223	nitrite transmembrane transporter activity
I6H86_RS07380	COG4651	solute:proton antiporter activity
I6H86_RS07380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I6H86_RS07385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS07430	COG2832	Protein of unknown function (DUF454)
I6H86_RS07435	COG3923	Primosomal replication protein n
I6H86_RS07450	COG3264	Mechanosensitive ion channel
I6H86_RS07450	COG1196	nuclear chromosome segregation
I6H86_RS07455	COG1309	transcriptional regulator
I6H86_RS07460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS07465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6H86_RS07480	COG0110	maltose O-acetyltransferase activity
I6H86_RS07490	COG0257	Belongs to the bacterial ribosomal protein bL36 family
I6H86_RS07500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
I6H86_RS07505	COG5507	3-demethylubiquinone-9 3-methyltransferase
I6H86_RS07510	COG2364	Membrane
I6H86_RS07515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6H86_RS07535	COG3695	enzyme binding
I6H86_RS07540	COG3126	Type III secretion system lipoprotein chaperone (YscW)
I6H86_RS07545	COG1946	Acyl-CoA thioesterase
I6H86_RS07550	COG0004	ammonium transporteR
I6H86_RS07555	COG0347	Belongs to the P(II) protein family
I6H86_RS07560	COG1132	(ABC) transporter
I6H86_RS07565	COG1132	(ABC) transporter
I6H86_RS07570	COG1522	sequence-specific DNA binding
I6H86_RS07585	COG4533	DNA binding
I6H86_RS07595	COG0824	Thioesterase
I6H86_RS07600	COG1555	photosystem II stabilization
I6H86_RS07605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I6H86_RS07610	COG0776	regulation of translation
I6H86_RS07615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
I6H86_RS07635	COG0271	Belongs to the BolA IbaG family
I6H86_RS07640	COG3056	Lipoprotein
I6H86_RS07645	COG2223	nitrite transmembrane transporter activity
I6H86_RS07650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
I6H86_RS07655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
I6H86_RS07660	COG1845	cytochrome c oxidase, subunit III
I6H86_RS07665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
I6H86_RS07675	COG2814	Major facilitator Superfamily
I6H86_RS07705	COG0142	geranyltranstransferase activity
I6H86_RS07715	COG0667	Aldo Keto reductase
I6H86_RS07720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
I6H86_RS07725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
I6H86_RS07740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I6H86_RS07740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
I6H86_RS07750	COG4238	major outer membrane lipoprotein
I6H86_RS07755	COG3248	Nucleoside-binding outer membrane protein
I6H86_RS07765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6H86_RS07770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
I6H86_RS07775	COG1862	Preprotein translocase
I6H86_RS07795	COG0450	alkyl hydroperoxide reductase
I6H86_RS07810	COG0583	DNA-binding transcription factor activity
I6H86_RS07815	COG0366	Alpha amylase catalytic
I6H86_RS07830	COG5002	protein histidine kinase activity
I6H86_RS07840	COG0420	3'-5' exonuclease activity
I6H86_RS07845	COG0419	ATPase involved in DNA repair
I6H86_RS07850	COG1940	carbohydrate kinase activity
I6H86_RS07865	COG4126	flavin adenine dinucleotide binding
I6H86_RS07885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I6H86_RS07890	COG3706	GGDEF domain
I6H86_RS07900	COG1785	Belongs to the alkaline phosphatase family
I6H86_RS07910	COG1609	Transcriptional regulator
I6H86_RS07915	COG2271	Major facilitator Superfamily
I6H86_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS07955	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
I6H86_RS07960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I6H86_RS07965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
I6H86_RS07975	COG0113	porphobilinogen synthase activity
I6H86_RS07985	COG2175	clavaminate synthase activity
I6H86_RS07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
I6H86_RS07995	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
I6H86_RS08000	COG4521	taurine ABC transporter
I6H86_RS08015	COG2271	Major facilitator Superfamily
I6H86_RS08020	COG1840	ABC-type Fe3 transport system, periplasmic component
I6H86_RS08030	COG3842	ATPase activity
I6H86_RS08035	COG2040	homocysteine
I6H86_RS08040	COG1609	Transcriptional regulator
I6H86_RS08070	COG3829	transcription factor binding
I6H86_RS08080	COG1280	lysine exporter protein (LysE YggA)
I6H86_RS08085	COG2814	Major facilitator Superfamily
I6H86_RS08100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS08110	COG1737	Transcriptional regulator
I6H86_RS08120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS08125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS08130	COG1120	ATPase activity
I6H86_RS08135	COG4774	siderophore transport
I6H86_RS08150	COG0814	amino acid
I6H86_RS08165	COG0791	NLP P60 protein
I6H86_RS08175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
I6H86_RS08180	COG1191	sigma factor activity
I6H86_RS08205	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
I6H86_RS08210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I6H86_RS08215	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
I6H86_RS08240	COG4786	Flagellar basal body rod
I6H86_RS08240	COG1256	bacterial-type flagellum assembly
I6H86_RS08250	COG1706	bacterial-type flagellum-dependent cell motility
I6H86_RS08260	COG4786	Flagellar basal body rod
I6H86_RS08280	COG1558	bacterial-type flagellum-dependent cell motility
I6H86_RS08285	COG1815	bacterial-type flagellum-dependent cell motility
I6H86_RS08305	COG2226	methyltransferase
I6H86_RS08310	COG1216	Glycosyl transferase, family 2
I6H86_RS08310	COG1442	glycosyl transferase family 8
I6H86_RS08345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
I6H86_RS08380	COG1987	bacterial-type flagellum assembly
I6H86_RS08385	COG1684	flagellar biosynthetic protein fliR
I6H86_RS08410	COG2200	EAL domain
I6H86_RS08430	COG2207	Transcriptional regulator
I6H86_RS08475	COG1732	Glycine betaine
I6H86_RS08480	COG2986	histidine ammonia-lyase
I6H86_RS08525	COG0411	ABC transporter
I6H86_RS08620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
I6H86_RS08640	COG2195	Cleaves the N-terminal amino acid of tripeptides
I6H86_RS08650	COG3034	peptidoglycan biosynthetic process
I6H86_RS08655	COG0121	glutamine amidotransferase
I6H86_RS08665	COG1960	acyl-CoA dehydrogenase activity
I6H86_RS08670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6H86_RS08690	COG2226	methyltransferase
I6H86_RS08700	COG1388	LysM domain
I6H86_RS08700	COG0741	lytic transglycosylase activity
I6H86_RS08705	COG2226	methyltransferase
I6H86_RS08715	COG0583	DNA-binding transcription factor activity
I6H86_RS08750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
I6H86_RS08765	COG1464	Belongs to the NlpA lipoprotein family
I6H86_RS08775	COG1720	tRNA m6t6A37 methyltransferase activity
I6H86_RS08785	COG3015	lipoprotein NlpE involved in copper resistance
I6H86_RS08790	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
I6H86_RS08805	COG4568	rho-dependent transcription termination
I6H86_RS08815	COG0346	lactoylglutathione lyase activity
I6H86_RS08820	COG1982	Orn Lys Arg decarboxylase major
I6H86_RS08860	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
I6H86_RS08875	COG0575	Belongs to the CDS family
I6H86_RS08885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
I6H86_RS08930	COG3835	regulator
I6H86_RS08935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6H86_RS08955	COG2860	membrane
I6H86_RS08985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6H86_RS08990	COG1120	ATPase activity
I6H86_RS08995	COG4774	siderophore transport
I6H86_RS09000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6H86_RS09005	COG1643	Atp-dependent helicase
I6H86_RS09010	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
I6H86_RS09030	COG0617	tRNA 3'-terminal CCA addition
I6H86_RS09035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
I6H86_RS09060	COG3121	Chaperone
I6H86_RS09065	COG3188	usher protein
I6H86_RS09090	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS09095	COG0842	Transport permease protein
I6H86_RS09100	COG1131	(ABC) transporter
I6H86_RS09105	COG0288	reversible hydration of carbon dioxide
I6H86_RS09110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
I6H86_RS09115	COG4993	Dehydrogenase
I6H86_RS09150	COG3064	Membrane
I6H86_RS09160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6H86_RS09165	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6H86_RS09170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
I6H86_RS09180	COG1113	amino acid transport
I6H86_RS09185	COG2211	Major facilitator Superfamily
I6H86_RS09190	COG3940	Belongs to the glycosyl hydrolase 43 family
I6H86_RS09195	COG3725	Membrane protein required for beta-lactamase induction
I6H86_RS09210	COG4969	Belongs to the N-Me-Phe pilin family
I6H86_RS09215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I6H86_RS09220	COG1459	type II secretion system
I6H86_RS09245	COG0494	nUDIX hydrolase
I6H86_RS09265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
I6H86_RS09270	COG0849	cell division
I6H86_RS09280	COG1181	Belongs to the D-alanine--D-alanine ligase family
I6H86_RS09295	COG0772	Belongs to the SEDS family
I6H86_RS09310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I6H86_RS09315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
I6H86_RS09320	COG0768	penicillin binding
I6H86_RS09340	COG1609	Transcriptional regulator
I6H86_RS09350	COG0028	Belongs to the TPP enzyme family
I6H86_RS09385	COG2814	Major facilitator Superfamily
I6H86_RS09405	COG1178	ABC-type Fe3 transport system permease component
I6H86_RS09415	COG0586	Pfam SNARE associated Golgi protein
I6H86_RS09435	COG0235	Class ii aldolase
I6H86_RS09440	COG0417	DNA replication proofreading
I6H86_RS09450	COG0564	pseudouridine synthase activity
I6H86_RS09455	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
I6H86_RS09465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I6H86_RS09510	COG2271	Major facilitator Superfamily
I6H86_RS09520	COG0644	oxidoreductase
I6H86_RS09600	COG0179	Fumarylacetoacetate (FAA) hydrolase
I6H86_RS09605	COG3493	citrate carrier protein
I6H86_RS09625	COG1047	Peptidyl-prolyl cis-trans
I6H86_RS09640	COG0196	riboflavin kinase activity
I6H86_RS09650	COG0583	DNA-binding transcription factor activity
I6H86_RS09670	COG1584	GPR1 FUN34 yaaH family protein
I6H86_RS09680	COG0521	Mo-molybdopterin cofactor biosynthetic process
I6H86_RS09690	COG1115	amino acid carrier protein
I6H86_RS09705	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
I6H86_RS09715	COG0527	aspartate kinase activity
I6H86_RS09715	COG0460	homoserine dehydrogenase
I6H86_RS09725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
I6H86_RS09735	COG0745	RESPONSE REGULATOR receiver
I6H86_RS09740	COG3045	CreA protein
I6H86_RS09745	COG2207	Transcriptional regulator
I6H86_RS09745	COG3708	Transcriptional regulator
I6H86_RS09765	COG0741	lytic transglycosylase activity
I6H86_RS09770	COG0488	(ABC) transporter
I6H86_RS09785	COG0560	Phosphoserine phosphatase
I6H86_RS09790	COG3726	membrane protein affecting hemolysin expression
I6H86_RS09805	COG3121	Chaperone
I6H86_RS09810	COG3188	usher protein
I6H86_RS09830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
I6H86_RS09840	COG1328	CTP reductase activity
I6H86_RS09845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6H86_RS09850	COG0084	hydrolase, TatD family'
I6H86_RS09855	COG4667	esterase of the alpha-beta hydrolase superfamily
I6H86_RS09865	COG2823	Periplasmic or secreted lipoprotein
I6H86_RS09875	COG1011	Hydrolase
I6H86_RS09880	COG0456	acetyltransferase
I6H86_RS09885	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
I6H86_RS09915	COG3706	GGDEF domain
I6H86_RS09920	COG4114	ferric iron reductase
I6H86_RS09925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I6H86_RS09930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6H86_RS09935	COG2197	response regulator
I6H86_RS09940	COG2197	response regulator
I6H86_RS09945	COG2966	Psort location CytoplasmicMembrane, score
I6H86_RS09960	COG1484	DNA-dependent DNA replication
I6H86_RS09980	COG0840	transmembrane signaling receptor activity
I6H86_RS09985	COG1966	Carbon starvation protein
I6H86_RS09990	COG2879	small protein
I6H86_RS09995	COG0523	cobalamin synthesis protein
I6H86_RS10005	COG1566	PFAM secretion protein HlyD family protein
I6H86_RS10015	COG5457	Domain of unknown function (DUF1127)
I6H86_RS10020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6H86_RS10025	COG5464	transposase or invertase
I6H86_RS10035	COG0626	cystathionine gamma-synthase activity
I6H86_RS10040	COG1301	dicarboxylic acid transport
I6H86_RS10045	COG0583	DNA-binding transcription factor activity
I6H86_RS10050	COG2733	membrane
I6H86_RS10055	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
I6H86_RS10060	COG1924	4 iron, 4 sulfur cluster binding
I6H86_RS10070	COG0477	Major facilitator Superfamily
I6H86_RS10075	COG0180	Tryptophanyl-tRNA synthetase
I6H86_RS10105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6H86_RS10105	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
I6H86_RS10190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I6H86_RS10225	COG0084	hydrolase, TatD family'
I6H86_RS10340	COG0582	viral genome integration into host DNA
I6H86_RS10350	COG1064	alcohol dehydrogenase
I6H86_RS10355	COG0433	COG0433 Predicted ATPase
I6H86_RS10360	COG0795	lipopolysaccharide-transporting ATPase activity
I6H86_RS10365	COG0795	lipopolysaccharide-transporting ATPase activity
I6H86_RS10375	COG2927	DNA polymerase III (CHI subunit)
I6H86_RS10380	COG0525	valine-tRNA ligase activity
I6H86_RS10420	COG2731	YhcH YjgK YiaL family protein
I6H86_RS10425	COG2235	arginine
I6H86_RS10435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I6H86_RS10440	COG1288	antiporter activity
I6H86_RS10445	COG1438	arginine binding
I6H86_RS10495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS10495	COG1263	PTS System
I6H86_RS10500	COG0366	Alpha amylase catalytic
I6H86_RS10510	COG1737	Transcriptional regulator
I6H86_RS10520	COG0383	alpha-mannosidase activity
I6H86_RS10525	COG0366	Alpha amylase catalytic
I6H86_RS10530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS10530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS10530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS10540	COG0602	queuosine metabolic process
I6H86_RS10545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS10545	COG3711	transcriptional antiterminator
I6H86_RS10560	COG3964	amidohydrolase
I6H86_RS10590	COG3783	Cytochrome b(562)
I6H86_RS10595	COG0312	modulator of DNA gyrase
I6H86_RS10605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
I6H86_RS10615	COG0840	transmembrane signaling receptor activity
I6H86_RS10620	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS10625	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS10630	COG1129	ABC transporter
I6H86_RS10635	COG1879	ABC-type sugar transport system periplasmic component
I6H86_RS10650	COG3157	Type VI secretion system effector, Hcp
I6H86_RS10655	COG2105	PFAM AIG2 family protein
I6H86_RS10660	COG2911	Protein conserved in bacteria
I6H86_RS10665	COG0729	surface antigen
I6H86_RS10675	COG1253	flavin adenine dinucleotide binding
I6H86_RS10685	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
I6H86_RS10690	COG1218	3'(2'),5'-bisphosphate nucleotidase
I6H86_RS10700	COG1733	regulation of RNA biosynthetic process
I6H86_RS10705	COG0702	epimerase
I6H86_RS10715	COG0697	spore germination
I6H86_RS10730	COG1113	amino acid transport
I6H86_RS10735	COG0545	Peptidyl-prolyl cis-trans isomerase
I6H86_RS10740	COG3061	Opacity-associated protein A
I6H86_RS10755	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
I6H86_RS10790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS10795	COG3414	Phosphotransferase system galactitol-specific IIB component
I6H86_RS10815	COG1073	alpha beta
I6H86_RS10820	COG3650	response to hydrogen peroxide
I6H86_RS10830	COG1960	acyl-CoA dehydrogenase activity
I6H86_RS10835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6H86_RS10855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
I6H86_RS10860	COG0330	HflC and HflK could
I6H86_RS10865	COG0330	HflC and HflK could
I6H86_RS10870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I6H86_RS10890	COG0860	N-Acetylmuramoyl-L-alanine amidase
I6H86_RS10895	COG0802	atpase or kinase
I6H86_RS10900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
I6H86_RS10900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I6H86_RS10905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I6H86_RS10940	COG1511	domain protein
I6H86_RS10940	COG3264	Mechanosensitive ion channel
I6H86_RS10955	COG1053	succinate dehydrogenase
I6H86_RS10960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
I6H86_RS11005	COG1509	lysine 2,3-aminomutase activity
I6H86_RS11030	COG0531	amino acid
I6H86_RS11035	COG3030	protein affecting phage T7 exclusion by the F plasmid
I6H86_RS11040	COG1027	Aspartate ammonia-lyase
I6H86_RS11045	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6H86_RS11060	COG1309	transcriptional regulator
I6H86_RS11075	COG0582	viral genome integration into host DNA
I6H86_RS11080	COG4974	Belongs to the 'phage' integrase family
I6H86_RS11090	COG3539	Fimbrial protein
I6H86_RS11095	COG3121	Chaperone
I6H86_RS11100	COG3188	usher protein
I6H86_RS11105	COG3539	Fimbrial protein
I6H86_RS11110	COG3539	Fimbrial protein
I6H86_RS11115	COG3539	Fimbrial protein
I6H86_RS11125	COG0840	transmembrane signaling receptor activity
I6H86_RS11130	COG0281	malic enzyme
I6H86_RS11135	COG3069	C4-dicarboxylate transmembrane transporter activity
I6H86_RS11145	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I6H86_RS11165	COG1609	Transcriptional regulator
I6H86_RS11175	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS11180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
I6H86_RS11190	COG0246	Mannitol dehydrogenase
I6H86_RS11200	COG1904	glucuronate isomerase
I6H86_RS11205	COG1312	Catalyzes the dehydration of D-mannonate
I6H86_RS11215	COG4771	TonB-dependent receptor
I6H86_RS11220	COG3720	iron ion transport
I6H86_RS11225	COG4558	Periplasmic binding protein
I6H86_RS11230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS11240	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
I6H86_RS11245	COG3290	protein histidine kinase activity
I6H86_RS11250	COG4565	transcriptional regulatory protein
I6H86_RS11255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
I6H86_RS11260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS11260	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS11305	COG2824	Alkylphosphonate utilization operon protein PhnA
I6H86_RS11310	COG2764	glyoxalase bleomycin resistance protein dioxygenase
I6H86_RS11315	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
I6H86_RS11320	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
I6H86_RS11325	COG3639	organic phosphonate transmembrane transporter activity
I6H86_RS11330	COG2188	Transcriptional regulator
I6H86_RS11335	COG3624	Phosphonate C-P lyase system protein PhnG
I6H86_RS11340	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
I6H86_RS11345	COG3626	phosphonate metabolism
I6H86_RS11350	COG3627	carbon phosphorus lyase activity
I6H86_RS11355	COG4107	phosphonate C-P lyase system protein PhnK
I6H86_RS11360	COG4778	phosphonate C-P lyase system protein PhnL
I6H86_RS11365	COG3454	Phosphonate metabolism
I6H86_RS11370	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
I6H86_RS11375	COG0456	acetyltransferase
I6H86_RS11380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I6H86_RS11395	COG0698	ribose 5-phosphate isomerase
I6H86_RS11400	COG1737	Transcriptional regulator
I6H86_RS11405	COG1879	ABC-type sugar transport system periplasmic component
I6H86_RS11410	COG1129	ABC transporter
I6H86_RS11415	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS11420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I6H86_RS11425	COG1940	carbohydrate kinase activity
I6H86_RS11430	COG0784	Response regulator, receiver
I6H86_RS11430	COG4191	Histidine kinase
I6H86_RS11435	COG1129	ABC transporter
I6H86_RS11440	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS11460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
I6H86_RS11460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
I6H86_RS11475	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
I6H86_RS11480	COG1301	dicarboxylic acid transport
I6H86_RS11485	COG4235	cytochrome complex assembly
I6H86_RS11490	COG3088	subunit of a heme lyase
I6H86_RS11495	COG1138	Cytochrome C-type biogenesis protein
I6H86_RS11500	COG3301	Polysulphide reductase, NrfD
I6H86_RS11505	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS11510	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
I6H86_RS11525	COG3162	membrane
I6H86_RS11535	COG1346	cytolysis
I6H86_RS11540	COG1380	Effector of murein hydrolase LrgA
I6H86_RS11545	COG0583	DNA-binding transcription factor activity
I6H86_RS11550	COG1943	Transposase
I6H86_RS11555	COG0025	NhaP-type Na H and K H
I6H86_RS11560	COG2252	PERMEase
I6H86_RS11570	COG0789	Transcriptional regulator
I6H86_RS11580	COG4943	cyclic-guanylate-specific phosphodiesterase activity
I6H86_RS11590	COG1595	DNA-templated transcription, initiation
I6H86_RS11595	COG3712	iron ion homeostasis
I6H86_RS11600	COG4772	TonB-dependent receptor
I6H86_RS11605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
I6H86_RS11610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS11615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS11620	COG1120	ATPase activity
I6H86_RS11625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I6H86_RS11635	COG0589	response to stress
I6H86_RS11640	COG0629	single-stranded DNA binding
I6H86_RS11650	COG2315	Protein conserved in bacteria
I6H86_RS11655	COG3700	Belongs to the class B bacterial acid phosphatase family
I6H86_RS11665	COG2204	response regulator
I6H86_RS11670	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
I6H86_RS11675	COG0471	metal ion transport
I6H86_RS11680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6H86_RS11685	COG0045	succinate-CoA ligase (ADP-forming) activity
I6H86_RS11690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6H86_RS11695	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6H86_RS11700	COG0567	Dehydrogenase, E1 component
I6H86_RS11705	COG1448	Aminotransferase
I6H86_RS11710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
I6H86_RS11730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I6H86_RS11745	COG3157	Type VI secretion system effector, Hcp
I6H86_RS11750	COG0735	belongs to the Fur family
I6H86_RS11755	COG3237	CsbD-like
I6H86_RS11760	COG0534	Mate efflux family protein
I6H86_RS11770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I6H86_RS11815	COG3833	ABC-type maltose transport systems, permease component
I6H86_RS11820	COG3223	Belongs to the PsiE family
I6H86_RS11830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6H86_RS11855	COG0527	aspartate kinase activity
I6H86_RS11870	COG1187	pseudouridine synthase activity
I6H86_RS11885	COG0646	methionine synthase
I6H86_RS11885	COG1410	methionine synthase
I6H86_RS11905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
I6H86_RS11915	COG0456	acetyltransferase
I6H86_RS11945	COG0151	Belongs to the GarS family
I6H86_RS11980	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
I6H86_RS11995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
I6H86_RS12000	COG2104	thiamine diphosphate biosynthetic process
I6H86_RS12020	COG1447	Phosphotransferase system cellobiose-specific component IIA
I6H86_RS12055	COG0250	Participates in transcription elongation, termination and antitermination
I6H86_RS12060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I6H86_RS12100	COG0812	UDP-N-acetylmuramate dehydrogenase activity
I6H86_RS12160	COG0583	DNA-binding transcription factor activity
I6H86_RS12195	COG2207	Transcriptional regulator
I6H86_RS12200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS12205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6H86_RS12210	COG1882	Formate acetyltransferase
I6H86_RS12215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS12220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS12225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS12225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6H86_RS12225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS12235	COG0371	Dehydrogenase
I6H86_RS12250	COG0583	DNA-binding transcription factor activity
I6H86_RS12260	COG0527	aspartate kinase activity
I6H86_RS12260	COG0460	homoserine dehydrogenase
I6H86_RS12265	COG0626	cystathionine gamma-synthase activity
I6H86_RS12280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I6H86_RS12285	COG1609	Transcriptional regulator
I6H86_RS12290	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
I6H86_RS12305	COG1575	Belongs to the MenA family. Type 1 subfamily
I6H86_RS12320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I6H86_RS12330	COG5499	transcription regulator containing HTH domain
I6H86_RS12335	COG4680	protein conserved in bacteria
I6H86_RS12340	COG1494	fructose-1,6-bisphosphatase
I6H86_RS12350	COG3152	Membrane
I6H86_RS12375	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
I6H86_RS12390	COG3678	ATP-independent chaperone mediated protein folding
I6H86_RS12395	COG0745	RESPONSE REGULATOR receiver
I6H86_RS12400	COG2205	protein histidine kinase activity
I6H86_RS12405	COG2258	MOSC domain
I6H86_RS12410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I6H86_RS12455	COG1454	alcohol dehydrogenase
I6H86_RS12470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I6H86_RS12500	COG3121	Chaperone
I6H86_RS12515	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS12520	COG2864	formate dehydrogenase
I6H86_RS12535	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
I6H86_RS12540	COG0456	acetyltransferase
I6H86_RS12555	COG1011	Hydrolase
I6H86_RS12565	COG1349	DNA-binding transcription factor activity
I6H86_RS12570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS12580	COG3684	Belongs to the aldolase LacD family
I6H86_RS12615	COG0174	glutamine synthetase
I6H86_RS12620	COG3852	Histidine kinase
I6H86_RS12635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I6H86_RS12660	COG0204	Acyl-transferase
I6H86_RS12675	COG3084	Protein conserved in bacteria
I6H86_RS12680	COG0746	molybdenum cofactor guanylyltransferase activity
I6H86_RS12685	COG1763	Mo-molybdopterin cofactor biosynthetic process
I6H86_RS12725	COG1739	Uncharacterized protein family UPF0029
I6H86_RS12765	COG0805	protein transport
I6H86_RS12785	COG3165	ubiquinone biosynthetic process from chorismate
I6H86_RS12795	COG1322	Protein conserved in bacteria
I6H86_RS12815	COG0583	DNA-binding transcription factor activity
I6H86_RS12820	COG0697	spore germination
I6H86_RS12825	COG0561	phosphatase activity
I6H86_RS12830	COG2267	carboxylic ester hydrolase activity
I6H86_RS12835	COG1280	lysine exporter protein (LysE YggA)
I6H86_RS12840	COG1280	lysine exporter protein (LysE YggA)
I6H86_RS12875	COG1011	Hydrolase
I6H86_RS12885	COG3159	Protein conserved in bacteria
I6H86_RS12920	COG2959	enzyme of heme biosynthesis
I6H86_RS12925	COG3071	HemY protein
I6H86_RS12970	COG2244	polysaccharide biosynthetic process
I6H86_RS12975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
I6H86_RS12980	COG0456	acetyltransferase
I6H86_RS12985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I6H86_RS12990	COG1088	dTDP-glucose 4,6-dehydratase activity
I6H86_RS12995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
I6H86_RS13015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
I6H86_RS13020	COG3118	belongs to the thioredoxin family
I6H86_RS13055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I6H86_RS13065	COG0583	DNA-binding transcription factor activity
I6H86_RS13080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I6H86_RS13085	COG3978	acetolactate synthase activity
I6H86_RS13100	COG0606	chelatase, subunit chli
I6H86_RS13105	COG3085	chromosome segregation
I6H86_RS13145	COG2186	Transcriptional regulator
I6H86_RS13150	COG0477	Major facilitator Superfamily
I6H86_RS13155	COG1609	Transcriptional regulator
I6H86_RS13160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS13170	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS13205	COG1522	sequence-specific DNA binding
I6H86_RS13210	COG0716	FMN binding
I6H86_RS13225	COG3312	ion transport
I6H86_RS13280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
I6H86_RS13285	COG0573	inorganic phosphate transmembrane transporter activity
I6H86_RS13290	COG0581	inorganic phosphate transmembrane transporter activity
I6H86_RS13300	COG0704	Plays a role in the regulation of phosphate uptake
I6H86_RS13305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6H86_RS13310	COG2252	PERMEase
I6H86_RS13315	COG0431	NADPH-dependent FMN reductase
I6H86_RS13320	COG2091	lysine biosynthetic process via aminoadipic acid
I6H86_RS13365	COG0592	DNA-directed DNA polymerase activity
I6H86_RS13380	COG0561	phosphatase activity
I6H86_RS13405	COG0823	Involved in the tonB-independent uptake of proteins
I6H86_RS13410	COG5645	(Lipo)protein
I6H86_RS13430	COG2188	Transcriptional regulator
I6H86_RS13445	COG2207	Transcriptional regulator
I6H86_RS13450	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
I6H86_RS13455	COG3119	arylsulfatase activity
I6H86_RS13460	COG2149	membrane
I6H86_RS13470	COG0641	radical SAM
I6H86_RS13480	COG2610	gluconate transmembrane transporter activity
I6H86_RS13485	COG0583	DNA-binding transcription factor activity
I6H86_RS13495	COG2814	Major facilitator Superfamily
I6H86_RS13515	COG0028	Belongs to the TPP enzyme family
I6H86_RS13520	COG0440	acetolactate synthase activity
I6H86_RS13530	COG2197	response regulator
I6H86_RS13540	COG2271	Major facilitator Superfamily
I6H86_RS13550	COG0800	Aldolase
I6H86_RS13555	COG3734	2-keto-3-deoxy-galactonokinase
I6H86_RS13560	COG2271	Major facilitator Superfamily
I6H86_RS13565	COG2721	sulfolactate sulfo-lyase activity
I6H86_RS13570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
I6H86_RS13575	COG1414	Transcriptional regulator
I6H86_RS13605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS13605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS13610	COG3715	PTS system
I6H86_RS13615	COG3716	PTS system mannose fructose sorbose family IID component
I6H86_RS13630	COG1464	Belongs to the NlpA lipoprotein family
I6H86_RS13640	COG3121	Chaperone
I6H86_RS13650	COG3539	Fimbrial protein
I6H86_RS13655	COG3121	Chaperone
I6H86_RS13665	COG0697	spore germination
I6H86_RS13670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
I6H86_RS13675	COG0604	alcohol dehydrogenase
I6H86_RS13680	COG0583	DNA-binding transcription factor activity
I6H86_RS13690	COG2982	Protein involved in outer membrane biogenesis
I6H86_RS13695	COG2233	PERMEase
I6H86_RS13700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I6H86_RS13705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6H86_RS13710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6H86_RS13730	COG2860	membrane
I6H86_RS13735	COG1561	YicC-like family, N-terminal region
I6H86_RS13760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I6H86_RS13790	COG1519	Transferase
I6H86_RS13795	COG0438	transferase activity, transferring glycosyl groups
I6H86_RS13800	COG0515	serine threonine protein kinase
I6H86_RS13805	COG1442	glycosyl transferase family 8
I6H86_RS13810	COG1442	glycosyl transferase family 8
I6H86_RS13820	COG0859	PFAM glycosyl transferase family 9
I6H86_RS13825	COG1215	transferase activity, transferring glycosyl groups
I6H86_RS13830	COG3307	-O-antigen
I6H86_RS13835	COG0859	PFAM glycosyl transferase family 9
I6H86_RS13840	COG0859	PFAM glycosyl transferase family 9
I6H86_RS13850	COG0156	8-amino-7-oxononanoate synthase activity
I6H86_RS13865	COG1216	Glycosyl transferase, family 2
I6H86_RS13870	COG2861	carbohydrate metabolic process
I6H86_RS13875	COG4942	peptidase
I6H86_RS13885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6H86_RS13890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I6H86_RS13905	COG1045	serine acetyltransferase
I6H86_RS13910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
I6H86_RS13920	COG2186	Transcriptional regulator
I6H86_RS13940	COG3722	fumarate hydratase activity
I6H86_RS13950	COG2213	PTS system mannitol-specific
I6H86_RS13950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS13960	COG1566	PFAM secretion protein HlyD family protein
I6H86_RS13965	COG0625	glutathione transferase activity
I6H86_RS13975	COG3276	selenocysteine insertion sequence binding
I6H86_RS13980	COG1454	alcohol dehydrogenase
I6H86_RS13985	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS13995	COG0235	Class ii aldolase
I6H86_RS14000	COG3623	hexulose-6-phosphate isomerase
I6H86_RS14005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
I6H86_RS14010	COG1070	Carbohydrate kinase
I6H86_RS14025	COG2731	YhcH YjgK YiaL family protein
I6H86_RS14035	COG1414	Transcriptional regulator
I6H86_RS14040	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS14045	COG3977	Valine--pyruvate aminotransferase
I6H86_RS14050	COG0366	Alpha amylase catalytic
I6H86_RS14055	COG2992	FlgJ-related protein
I6H86_RS14060	COG2207	Transcriptional regulator
I6H86_RS14060	COG1609	Transcriptional regulator
I6H86_RS14065	COG4214	carbohydrate transport
I6H86_RS14075	COG4213	ABC transporter substrate-binding protein
I6H86_RS14085	COG1070	Carbohydrate kinase
I6H86_RS14095	COG3274	enterobacterial common antigen metabolic process
I6H86_RS14115	COG1278	Cold shock
I6H86_RS14120	COG2944	sequence-specific DNA binding
I6H86_RS14140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS14150	COG1609	Transcriptional regulator
I6H86_RS14155	COG2885	chlorophyll binding
I6H86_RS14160	COG0243	molybdopterin cofactor binding
I6H86_RS14165	COG0456	acetyltransferase
I6H86_RS14170	COG2818	Glycosylase
I6H86_RS14175	COG5571	outer membrane autotransporter
I6H86_RS14180	COG2223	nitrite transmembrane transporter activity
I6H86_RS14195	COG0747	negative chemotaxis
I6H86_RS14200	COG0601	transmembrane transport
I6H86_RS14205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6H86_RS14210	COG0444	Belongs to the ABC transporter superfamily
I6H86_RS14215	COG4608	Belongs to the ABC transporter superfamily
I6H86_RS14220	COG2204	response regulator
I6H86_RS14225	COG0814	amino acid
I6H86_RS14265	COG1215	transferase activity, transferring glycosyl groups
I6H86_RS14275	COG0457	Tetratricopeptide repeat
I6H86_RS14275	COG3118	belongs to the thioredoxin family
I6H86_RS14280	COG2199	diguanylate cyclase activity
I6H86_RS14280	COG2200	EAL domain
I6H86_RS14300	COG2200	EAL domain
I6H86_RS14305	COG2982	Protein involved in outer membrane biogenesis
I6H86_RS14310	COG0477	Major facilitator Superfamily
I6H86_RS14315	COG1295	ribonuclease BN
I6H86_RS14320	COG0583	DNA-binding transcription factor activity
I6H86_RS14325	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS14340	COG1858	cytochrome C peroxidase
I6H86_RS14345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6H86_RS14350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
I6H86_RS14355	COG0339	signal peptide processing
I6H86_RS14370	COG1959	2 iron, 2 sulfur cluster binding
I6H86_RS14380	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
I6H86_RS14390	COG0589	response to stress
I6H86_RS14400	COG0306	phosphate transporter
I6H86_RS14405	COG2081	HI0933 family
I6H86_RS14410	COG2239	Acts as a magnesium transporter
I6H86_RS14415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS14420	COG0842	Transport permease protein
I6H86_RS14420	COG1129	ABC transporter
I6H86_RS14425	COG0842	Transport permease protein
I6H86_RS14440	COG0444	Belongs to the ABC transporter superfamily
I6H86_RS14445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6H86_RS14450	COG0601	transmembrane transport
I6H86_RS14455	COG0747	negative chemotaxis
I6H86_RS14460	COG2091	lysine biosynthetic process via aminoadipic acid
I6H86_RS14465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6H86_RS14470	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS14480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6H86_RS14505	COG1216	Glycosyl transferase, family 2
I6H86_RS14525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I6H86_RS14535	COG0204	Acyl-transferase
I6H86_RS14555	COG0628	permease
I6H86_RS14560	COG0477	Major facilitator Superfamily
I6H86_RS14570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
I6H86_RS14580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
I6H86_RS14590	COG3714	YhhN family
I6H86_RS14600	COG3776	membrane
I6H86_RS14605	COG0742	ribosomal rna small subunit methyltransferase
I6H86_RS14610	COG0552	protein localization to endoplasmic reticulum
I6H86_RS14615	COG2884	Cell division ATP-binding protein ftsE
I6H86_RS14620	COG2177	Part of the ABC transporter FtsEX involved in
I6H86_RS14630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I6H86_RS14635	COG0683	leucine binding
I6H86_RS14645	COG0683	leucine binding
I6H86_RS14655	COG4177	L-phenylalanine transmembrane transporter activity
I6H86_RS14660	COG0411	ABC transporter
I6H86_RS14665	COG0410	ABC transporter
I6H86_RS14690	COG0584	glycerophosphoryl diester phosphodiesterase
I6H86_RS14700	COG0405	Gamma-glutamyltransferase
I6H86_RS14720	COG3157	Type VI secretion system effector, Hcp
I6H86_RS14725	COG1247	-acetyltransferase
I6H86_RS14730	COG0673	inositol 2-dehydrogenase activity
I6H86_RS14735	COG1741	Belongs to the pirin family
I6H86_RS14740	COG1609	Transcriptional regulator
I6H86_RS14745	COG3265	gluconokinase activity
I6H86_RS14750	COG2610	gluconate transmembrane transporter activity
I6H86_RS14755	COG2095	MarC family integral membrane protein
I6H86_RS14760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I6H86_RS14785	COG0058	SHG alpha-glucan phosphorylase activity
I6H86_RS14790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I6H86_RS14805	COG1349	DNA-binding transcription factor activity
I6H86_RS14815	COG0058	SHG alpha-glucan phosphorylase activity
I6H86_RS14820	COG1640	4-alpha-glucanotransferase
I6H86_RS14825	COG2610	gluconate transmembrane transporter activity
I6H86_RS14835	COG1040	competence protein
I6H86_RS14855	COG1918	ferrous iron import across plasma membrane
I6H86_RS14860	COG2183	response to ionizing radiation
I6H86_RS14865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
I6H86_RS14890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I6H86_RS14895	COG1011	Hydrolase
I6H86_RS14905	COG0494	nUDIX hydrolase
I6H86_RS14910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
I6H86_RS14915	COG4972	Pilus assembly protein
I6H86_RS14920	COG3166	PFAM Fimbrial assembly family protein
I6H86_RS14935	COG4796	Type ii and iii secretion system protein
I6H86_RS14950	COG3266	domain, Protein
I6H86_RS14955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
I6H86_RS14960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
I6H86_RS14975	COG2188	Transcriptional regulator
I6H86_RS14985	COG3457	Alanine racemase
I6H86_RS14990	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
I6H86_RS14995	COG1735	metal-dependent hydrolase with the TIM-barrel fold
I6H86_RS15010	COG0626	cystathionine gamma-synthase activity
I6H86_RS15035	COG2146	nitrite reductase [NAD(P)H] activity
I6H86_RS15040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
I6H86_RS15070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I6H86_RS15075	COG1289	transmembrane transporter activity
I6H86_RS15085	COG1765	OsmC-like protein
I6H86_RS15090	COG3954	Phosphoribulokinase
I6H86_RS15100	COG0429	hydrolase of the alpha beta-hydrolase fold
I6H86_RS15130	COG0679	Auxin Efflux Carrier
I6H86_RS15140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I6H86_RS15150	COG0488	(ABC) transporter
I6H86_RS15165	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
I6H86_RS15170	COG1047	Peptidyl-prolyl cis-trans
I6H86_RS15180	COG0545	Peptidyl-prolyl cis-trans isomerase
I6H86_RS15185	COG2964	Protein conserved in bacteria
I6H86_RS15240	COG0051	transcription antitermination factor activity, RNA binding
I6H86_RS15345	COG0201	protein transport
I6H86_RS15375	COG0203	ribosomal protein L17
I6H86_RS15385	COG0789	Transcriptional regulator
I6H86_RS15390	COG3036	rescue of stalled ribosome
I6H86_RS15410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
I6H86_RS15420	COG0758	DNA mediated transformation
I6H86_RS15430	COG0551	DNA topoisomerase type I activity
I6H86_RS15450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
I6H86_RS15495	COG1126	abc transporter atp-binding protein
I6H86_RS15500	COG0765	amino acid transport
I6H86_RS15505	COG4597	amino acid ABC transporter
I6H86_RS15510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS15520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6H86_RS15525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
I6H86_RS15530	COG1309	transcriptional regulator
I6H86_RS15540	COG2189	Belongs to the N(4) N(6)-methyltransferase family
I6H86_RS15565	COG4145	pantothenate transmembrane transporter activity
I6H86_RS15570	COG3924	membrane
I6H86_RS15575	COG0439	Biotin carboxylase
I6H86_RS15580	COG0511	ligase activity, forming carbon-carbon bonds
I6H86_RS15600	COG0604	alcohol dehydrogenase
I6H86_RS15605	COG2200	EAL domain
I6H86_RS15605	COG2199	diguanylate cyclase activity
I6H86_RS15610	COG1077	Cell shape determining protein MreB Mrl
I6H86_RS15615	COG1792	Involved in formation and maintenance of cell shape
I6H86_RS15620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
I6H86_RS15635	COG3164	Protein of unknown function
I6H86_RS15640	COG0312	modulator of DNA gyrase
I6H86_RS15645	COG0583	DNA-binding transcription factor activity
I6H86_RS15665	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS15670	COG2732	(Barnase) inhibitor
I6H86_RS15690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6H86_RS15695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6H86_RS15700	COG3105	Protein conserved in bacteria
I6H86_RS15705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
I6H86_RS15720	COG0625	glutathione transferase activity
I6H86_RS15725	COG2969	positive regulation of protein catabolic process
I6H86_RS15755	COG2731	YhcH YjgK YiaL family protein
I6H86_RS15760	COG4804	nuclease activity
I6H86_RS15765	COG0493	'glutamate synthase
I6H86_RS15770	COG0067	glutamate synthase
I6H86_RS15770	COG0069	glutamate synthase activity
I6H86_RS15770	COG0070	glutamate synthase
I6H86_RS15775	COG1242	4 iron, 4 sulfur cluster binding
I6H86_RS15780	COG0784	Response regulator, receiver
I6H86_RS15780	COG2198	Histidine kinase
I6H86_RS15780	COG5002	protein histidine kinase activity
I6H86_RS15785	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
I6H86_RS15795	COG0515	serine threonine protein kinase
I6H86_RS15800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS15815	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I6H86_RS15825	COG1137	ATPase activity
I6H86_RS15830	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
I6H86_RS15835	COG3117	lipopolysaccharide transmembrane transporter activity
I6H86_RS15840	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
I6H86_RS15850	COG0530	calcium, potassium:sodium antiporter activity
I6H86_RS15855	COG1127	ABC transporter
I6H86_RS15860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
I6H86_RS15865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
I6H86_RS15870	COG2854	intermembrane phospholipid transfer
I6H86_RS15875	COG3113	response to antibiotic
I6H86_RS15880	COG5007	Belongs to the BolA IbaG family
I6H86_RS15890	COG3423	Transcriptional regulator
I6H86_RS15895	COG0142	geranyltranstransferase activity
I6H86_RS15910	COG0697	spore germination
I6H86_RS15920	COG2027	D-alanyl-D-alanine carboxypeptidase
I6H86_RS15930	COG1534	Rna-binding protein
I6H86_RS15945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
I6H86_RS15955	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
I6H86_RS15980	COG0195	Participates in both transcription termination and antitermination
I6H86_RS16000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
I6H86_RS16020	COG0513	Belongs to the DEAD box helicase family
I6H86_RS16025	COG0814	amino acid
I6H86_RS16030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
I6H86_RS16035	COG0826	peptidase U32
I6H86_RS16040	COG0826	peptidase U32
I6H86_RS16045	COG3154	lipid carrier protein
I6H86_RS16050	COG3153	acetyltransferase
I6H86_RS16065	COG0702	epimerase
I6H86_RS16070	COG0701	Predicted permease
I6H86_RS16075	COG2823	Periplasmic or secreted lipoprotein
I6H86_RS16095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
I6H86_RS16105	COG1263	PTS System
I6H86_RS16105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS16115	COG2222	sugar isomerase
I6H86_RS16120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I6H86_RS16125	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS16130	COG3716	PTS system mannose fructose sorbose family IID component
I6H86_RS16140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS16150	COG1349	DNA-binding transcription factor activity
I6H86_RS16155	COG2721	sulfolactate sulfo-lyase activity
I6H86_RS16165	COG2084	Dehydrogenase
I6H86_RS16170	COG1929	Belongs to the glycerate kinase type-1 family
I6H86_RS16185	COG0583	DNA-binding transcription factor activity
I6H86_RS16205	COG1882	Formate acetyltransferase
I6H86_RS16210	COG0251	oxidation-reduction process
I6H86_RS16215	COG1760	l-serine dehydratase
I6H86_RS16220	COG0814	amino acid
I6H86_RS16235	COG1741	Belongs to the pirin family
I6H86_RS16240	COG0583	DNA-binding transcription factor activity
I6H86_RS16245	COG3152	Membrane
I6H86_RS16250	COG0435	Glutathione S-transferase
I6H86_RS16255	COG2259	Doxx family
I6H86_RS16265	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
I6H86_RS16270	COG4575	ribosome binding
I6H86_RS16275	COG1422	Protein of unknown function (DUF1090)
I6H86_RS16285	COG0586	Pfam SNARE associated Golgi protein
I6H86_RS16290	COG2186	Transcriptional regulator
I6H86_RS16295	COG2271	Major facilitator Superfamily
I6H86_RS16305	COG2721	sulfolactate sulfo-lyase activity
I6H86_RS16320	COG0673	inositol 2-dehydrogenase activity
I6H86_RS16325	COG1451	nucleotide metabolic process
I6H86_RS16335	COG0446	pyridine nucleotide-disulphide oxidoreductase
I6H86_RS16335	COG1902	pentaerythritol trinitrate reductase activity
I6H86_RS16345	COG0840	transmembrane signaling receptor activity
I6H86_RS16355	COG1695	Transcriptional regulator
I6H86_RS16360	COG2375	cellular response to nickel ion
I6H86_RS16405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
I6H86_RS16455	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS16460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
I6H86_RS16475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I6H86_RS16490	COG4991	sh3 domain protein
I6H86_RS16495	COG3025	triphosphatase activity
I6H86_RS16530	COG3384	dioxygenase
I6H86_RS16535	COG0754	glutathionylspermidine amidase activity
I6H86_RS16545	COG1538	Outer membrane efflux protein
I6H86_RS16550	COG0494	nUDIX hydrolase
I6H86_RS16555	COG3151	Protein conserved in bacteria
I6H86_RS16560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
I6H86_RS16565	COG3150	esterase
I6H86_RS16585	COG2211	Major facilitator Superfamily
I6H86_RS16590	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
I6H86_RS16595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
I6H86_RS16600	COG2249	NAD(P)H dehydrogenase (quinone) activity
I6H86_RS16615	COG3111	PFAM Bacterial OB fold (BOF) protein
I6H86_RS16645	COG0656	L-ascorbic acid biosynthetic process
I6H86_RS16650	COG1979	alcohol dehydrogenase
I6H86_RS16655	COG2207	Transcriptional regulator
I6H86_RS16660	COG0586	Pfam SNARE associated Golgi protein
I6H86_RS16665	COG0626	cystathionine gamma-synthase activity
I6H86_RS16675	COG0848	biopolymer transport protein
I6H86_RS16695	COG0667	Aldo Keto reductase
I6H86_RS16705	COG0840	transmembrane signaling receptor activity
I6H86_RS16715	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
I6H86_RS16720	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS16725	COG5557	Pfam Polysulphide reductase, NrfD
I6H86_RS16730	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
I6H86_RS16735	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I6H86_RS16740	COG1773	rubredoxin
I6H86_RS16750	COG0298	carbon dioxide binding
I6H86_RS16755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
I6H86_RS16765	COG0625	glutathione transferase activity
I6H86_RS16770	COG0243	molybdopterin cofactor binding
I6H86_RS16775	COG0754	glutathionylspermidine amidase activity
I6H86_RS16780	COG1064	alcohol dehydrogenase
I6H86_RS16785	COG2207	Transcriptional regulator
I6H86_RS16825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS16825	COG0784	Response regulator, receiver
I6H86_RS16825	COG2198	Histidine kinase
I6H86_RS16825	COG2205	protein histidine kinase activity
I6H86_RS16830	COG2197	response regulator
I6H86_RS16850	COG3501	Rhs element vgr protein
I6H86_RS16930	COG1811	Na channel or pump
I6H86_RS16935	COG1982	Orn Lys Arg decarboxylase major
I6H86_RS16940	COG2211	Major facilitator Superfamily
I6H86_RS16955	COG1194	a g-specific adenine glycosylase
I6H86_RS16965	COG3171	Protein conserved in bacteria
I6H86_RS16975	COG0252	asparaginase activity
I6H86_RS16980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I6H86_RS16995	COG0762	integral membrane protein
I6H86_RS17000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I6H86_RS17005	COG2805	Type II/IV secretion system protein
I6H86_RS17020	COG0189	ligase activity
I6H86_RS17025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I6H86_RS17030	COG2356	endonuclease I
I6H86_RS17040	COG2814	Major facilitator Superfamily
I6H86_RS17060	COG1166	arginine decarboxylase activity
I6H86_RS17080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I6H86_RS17085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS17090	COG2213	PTS system mannitol-specific
I6H86_RS17095	COG1063	alcohol dehydrogenase
I6H86_RS17100	COG1494	fructose-1,6-bisphosphatase
I6H86_RS17110	COG1072	(Pantothenic acid kinase))
I6H86_RS17115	COG1122	ATPase activity
I6H86_RS17120	COG1122	ATPase activity
I6H86_RS17150	COG0191	fructose-bisphosphate aldolase activity
I6H86_RS17155	COG0549	Belongs to the carbamate kinase family
I6H86_RS17160	COG2271	Major facilitator Superfamily
I6H86_RS17165	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6H86_RS17170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
I6H86_RS17180	COG0583	DNA-binding transcription factor activity
I6H86_RS17185	COG0668	transmembrane transport
I6H86_RS17195	COG2968	Membrane
I6H86_RS17210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I6H86_RS17215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I6H86_RS17235	COG0006	proline dipeptidase activity
I6H86_RS17240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6H86_RS17245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6H86_RS17265	COG2723	6-phospho-beta-galactosidase activity
I6H86_RS17270	COG1737	Transcriptional regulator
I6H86_RS17280	COG1272	protein, Hemolysin III
I6H86_RS17290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
I6H86_RS17300	COG0716	FMN binding
I6H86_RS17315	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I6H86_RS17335	COG4942	peptidase
I6H86_RS17345	COG1556	Lactate utilization protein
I6H86_RS17350	COG1139	Iron-sulfur cluster binding protein
I6H86_RS17355	COG0247	lactate metabolic process
I6H86_RS17360	COG1620	l-lactate permease
I6H86_RS17365	COG3592	Divergent 4Fe-4S mono-cluster
I6H86_RS17370	COG2388	GCN5-related N-acetyl-transferase
I6H86_RS17390	COG3121	Chaperone
I6H86_RS17410	COG2771	luxR family
I6H86_RS17425	COG0814	amino acid
I6H86_RS17440	COG0183	Belongs to the thiolase family
I6H86_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS17460	COG1794	racemase activity, acting on amino acids and derivatives
I6H86_RS17465	COG0583	DNA-binding transcription factor activity
I6H86_RS17475	COG1609	Transcriptional regulator
I6H86_RS17495	COG0667	Aldo Keto reductase
I6H86_RS17505	COG0861	Integral membrane protein TerC family
I6H86_RS17535	COG2165	general secretion pathway protein
I6H86_RS17540	COG4795	General secretion pathway protein
I6H86_RS17550	COG4967	type IV pilus modification protein PilV
I6H86_RS17555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
I6H86_RS17565	COG1074	ATP-dependent DNA helicase activity
I6H86_RS17570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I6H86_RS17575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
I6H86_RS17575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
I6H86_RS17580	COG0860	N-Acetylmuramoyl-L-alanine amidase
I6H86_RS17600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
I6H86_RS17605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
I6H86_RS17610	COG2166	iron-sulfur cluster assembly
I6H86_RS17615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I6H86_RS17625	COG0583	DNA-binding transcription factor activity
I6H86_RS17630	COG2363	Small membrane protein
I6H86_RS17640	COG1349	DNA-binding transcription factor activity
I6H86_RS17660	COG0738	Major facilitator superfamily
I6H86_RS17665	COG0235	Class ii aldolase
I6H86_RS17670	COG1454	alcohol dehydrogenase
I6H86_RS17680	COG1760	l-serine dehydratase
I6H86_RS17685	COG0814	amino acid
I6H86_RS17690	COG1611	Belongs to the LOG family
I6H86_RS17705	COG3098	single-species biofilm formation
I6H86_RS17710	COG0564	pseudouridine synthase activity
I6H86_RS17715	COG0716	FMN binding
I6H86_RS17720	COG2271	Major facilitator Superfamily
I6H86_RS17725	COG4948	Mandelate Racemase Muconate Lactonizing
I6H86_RS17730	COG4948	Mandelate Racemase Muconate Lactonizing
I6H86_RS17735	COG1929	Belongs to the glycerate kinase type-1 family
I6H86_RS17740	COG3437	response regulator, receiver
I6H86_RS17740	COG4999	Histidine kinase
I6H86_RS17740	COG3850	Histidine kinase
I6H86_RS17740	COG2205	protein histidine kinase activity
I6H86_RS17750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
I6H86_RS17755	COG3956	TIGRFAM MazG family protein
I6H86_RS17770	COG0602	queuosine metabolic process
I6H86_RS17775	COG1070	Carbohydrate kinase
I6H86_RS17780	COG2223	nitrite transmembrane transporter activity
I6H86_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS17790	COG0277	FAD linked oxidase domain protein
I6H86_RS17795	COG0477	Major facilitator Superfamily
I6H86_RS17800	COG2086	electron transfer activity
I6H86_RS17805	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
I6H86_RS17810	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
I6H86_RS17815	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
I6H86_RS17820	COG0644	oxidoreductase
I6H86_RS17825	COG0720	synthase
I6H86_RS17845	COG2234	aminopeptidase activity
I6H86_RS17900	COG1388	LysM domain
I6H86_RS17900	COG4942	peptidase
I6H86_RS17915	COG0163	prenyltransferase activity
I6H86_RS17920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
I6H86_RS17935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS17940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS17945	COG1121	(ABC) transporter
I6H86_RS17970	COG0309	Hydrogenase expression formation protein (HypE)
I6H86_RS17975	COG0409	Hydrogenase expression formation protein
I6H86_RS17980	COG0298	carbon dioxide binding
I6H86_RS17985	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
I6H86_RS17990	COG0375	protein maturation
I6H86_RS18000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS18005	COG0651	ATP synthesis coupled electron transport
I6H86_RS18010	COG0650	Formate hydrogenlyase subunit 4
I6H86_RS18015	COG3261	NADH dehydrogenase
I6H86_RS18015	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
I6H86_RS18020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6H86_RS18025	COG3260	NADH ubiquinone oxidoreductase 20
I6H86_RS18035	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
I6H86_RS18040	COG2723	6-phospho-beta-galactosidase activity
I6H86_RS18045	COG1263	PTS System
I6H86_RS18045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS18050	COG1609	Transcriptional regulator
I6H86_RS18055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS18060	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
I6H86_RS18085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
I6H86_RS18085	COG0517	IMP dehydrogenase activity
I6H86_RS18090	COG1349	DNA-binding transcription factor activity
I6H86_RS18095	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
I6H86_RS18110	COG3732	PTS system glucitol sorbitol-specific
I6H86_RS18115	COG3730	PTS system glucitol sorbitol-specific
I6H86_RS18120	COG2951	lytic endotransglycosylase activity
I6H86_RS18130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6H86_RS18140	COG1546	Belongs to the CinA family
I6H86_RS18160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
I6H86_RS18190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6H86_RS18195	COG1238	metal cluster binding
I6H86_RS18210	COG2814	Major facilitator Superfamily
I6H86_RS18215	COG1566	PFAM secretion protein HlyD family protein
I6H86_RS18220	COG1846	Transcriptional regulator
I6H86_RS18230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I6H86_RS18235	COG2814	Major facilitator Superfamily
I6H86_RS18245	COG4176	ABC-type proline glycine betaine transport system permease component
I6H86_RS18275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
I6H86_RS18285	COG4575	ribosome binding
I6H86_RS18305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
I6H86_RS18310	COG1652	LysM domain
I6H86_RS18315	COG1802	Transcriptional regulator
I6H86_RS18320	COG1113	amino acid transport
I6H86_RS18325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
I6H86_RS18330	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS18335	COG0579	oxidoreductase
I6H86_RS18400	COG3962	Belongs to the TPP enzyme family
I6H86_RS18405	COG0673	inositol 2-dehydrogenase activity
I6H86_RS18420	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS18425	COG0673	inositol 2-dehydrogenase activity
I6H86_RS18430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS18440	COG3718	enzyme involved in inositol metabolism
I6H86_RS18445	COG0840	transmembrane signaling receptor activity
I6H86_RS18450	COG1129	ABC transporter
I6H86_RS18455	COG1172	Belongs to the binding-protein-dependent transport system permease family
I6H86_RS18495	COG3477	response to acidic pH
I6H86_RS18590	COG0210	DNA helicase
I6H86_RS18595	COG0582	viral genome integration into host DNA
I6H86_RS18610	COG2867	negative regulation of translational initiation
I6H86_RS18620	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6H86_RS18625	COG0497	DNA recombination
I6H86_RS18640	COG4536	flavin adenine dinucleotide binding
I6H86_RS18645	COG4137	Cytochrome C assembly protein
I6H86_RS18650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I6H86_RS18685	COG2885	chlorophyll binding
I6H86_RS18690	COG2199	diguanylate cyclase activity
I6H86_RS18705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I6H86_RS18710	COG1605	Chorismate mutase
I6H86_RS18710	COG0287	Prephenate dehydrogenase
I6H86_RS18715	COG0077	Prephenate dehydratase
I6H86_RS18715	COG1605	Chorismate mutase
I6H86_RS18725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
I6H86_RS18730	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I6H86_RS18735	COG0564	pseudouridine synthase activity
I6H86_RS18745	COG0542	response to heat
I6H86_RS18770	COG0477	Major facilitator Superfamily
I6H86_RS18775	COG5544	Lipoprotein
I6H86_RS18780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6H86_RS18790	COG3148	PFAM DTW domain containing protein
I6H86_RS18795	COG3118	belongs to the thioredoxin family
I6H86_RS18800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6H86_RS18815	COG0513	Belongs to the DEAD box helicase family
I6H86_RS18825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
I6H86_RS18840	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
I6H86_RS18845	COG3026	antisigma factor binding
I6H86_RS18850	COG3086	response to oxidative stress
I6H86_RS18860	COG0681	Belongs to the peptidase S26 family
I6H86_RS18880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
I6H86_RS18890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS18895	COG1737	Transcriptional regulator
I6H86_RS18905	COG0560	Phosphoserine phosphatase
I6H86_RS18925	COG2205	protein histidine kinase activity
I6H86_RS18930	COG3170	Tfp pilus assembly protein FimV
I6H86_RS18935	COG2204	response regulator
I6H86_RS18940	COG0347	Belongs to the P(II) protein family
I6H86_RS18955	COG1940	carbohydrate kinase activity
I6H86_RS18960	COG0457	Tetratricopeptide repeat
I6H86_RS18965	COG2814	Major facilitator Superfamily
I6H86_RS18965	COG0477	Major facilitator Superfamily
I6H86_RS18970	COG2017	converts alpha-aldose to the beta-anomer
I6H86_RS18975	COG2814	Major facilitator Superfamily
I6H86_RS18980	COG3711	transcriptional antiterminator
I6H86_RS18985	COG3683	transport system, periplasmic component
I6H86_RS18990	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
I6H86_RS19015	COG0822	iron-sulfur transferase activity
I6H86_RS19035	COG0633	Ferredoxin
I6H86_RS19040	COG2975	iron-sulfur cluster assembly
I6H86_RS19055	COG2897	thiosulfate sulfurtransferase activity
I6H86_RS19060	COG2373	Large extracellular alpha-helical protein
I6H86_RS19065	COG4953	penicillin-binding protein 1C
I6H86_RS19095	COG2976	Protein conserved in bacteria
I6H86_RS19115	COG1645	bacterial-type flagellum-dependent swarming motility
I6H86_RS19125	COG0516	GMP reductase activity
I6H86_RS19125	COG0517	IMP dehydrogenase activity
I6H86_RS19150	COG2200	EAL domain
I6H86_RS19165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I6H86_RS19180	COG2723	6-phospho-beta-galactosidase activity
I6H86_RS19190	COG2233	PERMEase
I6H86_RS19200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
I6H86_RS19205	COG1446	asparaginase
I6H86_RS19220	COG1393	Belongs to the ArsC family
I6H86_RS19225	COG4783	chaperone-mediated protein folding
I6H86_RS19230	COG0628	permease
I6H86_RS19235	COG3366	ferrous iron transmembrane transporter activity
I6H86_RS19240	COG0700	Nucleoside recognition
I6H86_RS19245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
I6H86_RS19250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I6H86_RS19255	COG2716	regulation of RNA biosynthetic process
I6H86_RS19265	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
I6H86_RS19275	COG2321	neutral zinc metallopeptidase
I6H86_RS19285	COG0400	carboxylic ester hydrolase activity
I6H86_RS19300	COG1393	Belongs to the ArsC family
I6H86_RS19310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
I6H86_RS19315	COG3850	Histidine kinase
I6H86_RS19320	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS19320	COG0493	'glutamate synthase
I6H86_RS19330	COG5342	invasion associated locus B
I6H86_RS19335	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
I6H86_RS19430	COG2207	Transcriptional regulator
I6H86_RS19440	COG0860	N-Acetylmuramoyl-L-alanine amidase
I6H86_RS19460	COG2837	iron assimilation
I6H86_RS19465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I6H86_RS19470	COG1263	PTS System
I6H86_RS19470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6H86_RS19480	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
I6H86_RS19500	COG4150	thiosulfate binding
I6H86_RS19505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
I6H86_RS19510	COG4208	sulfate ABC transporter
I6H86_RS19515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
I6H86_RS19555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS19580	COG3530	Putative quorum-sensing-regulated virulence factor
I6H86_RS19585	COG0385	Bile acid
I6H86_RS19590	COG0583	DNA-binding transcription factor activity
I6H86_RS19600	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
I6H86_RS19605	COG2211	Major facilitator Superfamily
I6H86_RS19610	COG0583	DNA-binding transcription factor activity
I6H86_RS19640	COG3415	Transposase
I6H86_RS19645	COG3415	Transposase
I6H86_RS19660	COG2199	diguanylate cyclase activity
I6H86_RS19660	COG2200	EAL domain
I6H86_RS19665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I6H86_RS19680	COG0667	Aldo Keto reductase
I6H86_RS19685	COG3961	Belongs to the TPP enzyme family
I6H86_RS19700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS19705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS19710	COG0006	proline dipeptidase activity
I6H86_RS19715	COG1363	Peptidase, m42
I6H86_RS19720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS19720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS19720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
I6H86_RS19725	COG2207	Transcriptional regulator
I6H86_RS19730	COG3279	Response regulator of the LytR AlgR family
I6H86_RS19735	COG3275	phosphorelay sensor kinase activity
I6H86_RS19740	COG0436	Aminotransferase
I6H86_RS19750	COG1560	Kdo2-lipid A biosynthetic process
I6H86_RS19765	COG1716	ATPase activity
I6H86_RS19765	COG5001	Diguanylate cyclase
I6H86_RS19775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
I6H86_RS19790	COG0583	DNA-binding transcription factor activity
I6H86_RS19800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
I6H86_RS19805	COG2199	diguanylate cyclase activity
I6H86_RS19805	COG2202	Pas domain
I6H86_RS19805	COG2200	EAL domain
I6H86_RS19820	COG2814	Major facilitator Superfamily
I6H86_RS19830	COG2116	formate transmembrane transporter activity
I6H86_RS19840	COG2067	long-chain fatty acid transport protein
I6H86_RS19845	COG3691	Protein conserved in bacteria
I6H86_RS19860	COG2062	phosphohistidine phosphatase, SixA
I6H86_RS19885	COG0730	response to heat
I6H86_RS19890	COG3101	peptidyl-lysine hydroxylation
I6H86_RS19905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6H86_RS19930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I6H86_RS19940	COG0586	Pfam SNARE associated Golgi protein
I6H86_RS19950	COG0285	dihydrofolate synthase activity
I6H86_RS19955	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
I6H86_RS19960	COG1286	toxin biosynthetic process
I6H86_RS19965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
I6H86_RS19980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6H86_RS19990	COG4160	amino acid transport
I6H86_RS19995	COG4598	ABC transporter
I6H86_RS20000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6H86_RS20005	COG1090	epimerase
I6H86_RS20010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
I6H86_RS20015	COG0625	glutathione transferase activity
I6H86_RS20020	COG0622	Phosphoesterase
I6H86_RS20030	COG1609	Transcriptional regulator
I6H86_RS20035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6H86_RS20045	COG3037	sugar-specific permease SgaT UlaA
I6H86_RS20050	COG3959	Transketolase, thiamine diphosphate binding domain
I6H86_RS20055	COG3958	Transketolase
I6H86_RS20060	COG1288	antiporter activity
I6H86_RS20085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6H86_RS20090	COG0490	domain, Protein
I6H86_RS20090	COG0471	metal ion transport
I6H86_RS20100	COG0436	Aminotransferase
I6H86_RS20105	COG0583	DNA-binding transcription factor activity
I6H86_RS20150	COG0839	Belongs to the complex I subunit 6 family
I6H86_RS20160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
I6H86_RS20165	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
I6H86_RS20175	COG0784	Response regulator, receiver
I6H86_RS20175	COG0835	chemotaxis
I6H86_RS20185	COG2153	protein acetylation
I6H86_RS20190	COG4575	ribosome binding
I6H86_RS20195	COG1169	isochorismate synthase
I6H86_RS20240	COG0247	lactate metabolic process
I6H86_RS20250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
I6H86_RS20255	COG2271	Major facilitator Superfamily
I6H86_RS20260	COG0584	glycerophosphoryl diester phosphodiesterase
I6H86_RS20265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
I6H86_RS20275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6H86_RS20290	COG0183	Belongs to the thiolase family
I6H86_RS20295	COG2031	fatty acid transporter
I6H86_RS20300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
I6H86_RS20305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
I6H86_RS20310	COG2204	response regulator
I6H86_RS20315	COG3852	Histidine kinase
I6H86_RS20325	COG2197	response regulator
I6H86_RS20330	COG2198	Histidine kinase
I6H86_RS20330	COG0642	Histidine kinase
I6H86_RS20345	COG2169	Transcriptional regulator
I6H86_RS20345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I6H86_RS20350	COG3145	DNA-N1-methyladenine dioxygenase activity
I6H86_RS20355	COG4615	Cyclic peptide transporter
I6H86_RS20360	COG2239	Acts as a magnesium transporter
I6H86_RS20375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS20375	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
I6H86_RS20380	COG3062	negative regulation of establishment of protein localization
I6H86_RS20390	COG0437	4 iron, 4 sulfur cluster binding
I6H86_RS20395	COG0348	domain, Protein
I6H86_RS20400	COG3043	anaerobic respiration
I6H86_RS20405	COG3005	denitrification pathway
I6H86_RS20410	COG4133	protoheme IX ABC transporter activity
I6H86_RS20420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6H86_RS20425	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
I6H86_RS20435	COG1138	Cytochrome C-type biogenesis protein
I6H86_RS20440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6H86_RS20445	COG3088	subunit of a heme lyase
I6H86_RS20445	COG4235	cytochrome complex assembly
I6H86_RS20450	COG2197	response regulator
I6H86_RS20480	COG1061	Type III restriction enzyme res subunit
I6H86_RS20485	COG1187	pseudouridine synthase activity
I6H86_RS20490	COG2814	Major facilitator Superfamily
I6H86_RS20500	COG4172	Belongs to the ABC transporter superfamily
I6H86_RS20505	COG4239	(ABC) transporter, permease
I6H86_RS20510	COG4174	ABC transporter (Permease)
I6H86_RS20515	COG4166	transmembrane transport
I6H86_RS20520	COG2200	EAL domain
I6H86_RS20525	COG0791	NLP P60 protein
I6H86_RS20530	COG0671	phosphoesterase, PA-phosphatase related
I6H86_RS20535	COG0523	cobalamin synthesis protein
I6H86_RS20540	COG0246	Mannitol dehydrogenase
I6H86_RS20570	COG1105	Belongs to the carbohydrate kinase PfkB family
I6H86_RS20575	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
I6H86_RS20575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS20575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6H86_RS20580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS20585	COG2313	pseudouridylate synthase activity
I6H86_RS20590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
I6H86_RS20595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS20595	COG1522	sequence-specific DNA binding
I6H86_RS20605	COG2855	membrane
I6H86_RS20610	COG0583	DNA-binding transcription factor activity
I6H86_RS20615	COG0833	amino acid
I6H86_RS20620	COG4771	TonB-dependent receptor
I6H86_RS20625	COG2271	Major facilitator Superfamily
I6H86_RS20630	COG0560	Phosphoserine phosphatase
I6H86_RS20635	COG1760	l-serine dehydratase
I6H86_RS20655	COG2311	Membrane
I6H86_RS20670	COG1129	ABC transporter
I6H86_RS20685	COG2949	membrane
I6H86_RS20695	COG1346	cytolysis
I6H86_RS20710	COG2271	Major facilitator Superfamily
I6H86_RS20725	COG0625	glutathione transferase activity
I6H86_RS20730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
I6H86_RS20735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I6H86_RS20740	COG1538	Outer membrane efflux protein
I6H86_RS20745	COG0586	Pfam SNARE associated Golgi protein
I6H86_RS20755	COG1686	Belongs to the peptidase S11 family
I6H86_RS20760	COG0277	FAD linked oxidase domain protein
I6H86_RS20765	COG1472	Belongs to the glycosyl hydrolase 3 family
I6H86_RS20770	COG1732	Glycine betaine
I6H86_RS20775	COG1174	glycine betaine transport
I6H86_RS20780	COG1125	glycine betaine transport
I6H86_RS20785	COG1174	glycine betaine transport
I6H86_RS20795	COG0789	Transcriptional regulator
I6H86_RS20800	COG3275	phosphorelay sensor kinase activity
I6H86_RS20810	COG4807	Protein conserved in bacteria
I6H86_RS20835	COG3121	Chaperone
I6H86_RS20840	COG3188	usher protein
I6H86_RS20850	COG5455	response to cobalt ion
I6H86_RS20860	COG0351	phosphomethylpyrimidine kinase
I6H86_RS20865	COG2188	Transcriptional regulator
I6H86_RS20870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
I6H86_RS20875	COG1397	ADP-ribosylglycohydrolase
I6H86_RS20880	COG2211	Major facilitator Superfamily
I6H86_RS20885	COG1830	Aldolase
I6H86_RS20890	COG1070	Carbohydrate kinase
I6H86_RS20915	COG1070	Carbohydrate kinase
I6H86_RS20925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6H86_RS20945	COG0826	peptidase U32
I6H86_RS20950	COG0745	RESPONSE REGULATOR receiver
I6H86_RS20955	COG2205	protein histidine kinase activity
I6H86_RS20985	COG0443	Heat shock 70 kDa protein
I6H86_RS20990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
I6H86_RS20995	COG5002	protein histidine kinase activity
I6H86_RS20995	COG3447	MASE1 domain protein
I6H86_RS20995	COG5001	Diguanylate cyclase
I6H86_RS21010	COG2982	Protein involved in outer membrane biogenesis
I6H86_RS21015	COG1253	flavin adenine dinucleotide binding
I6H86_RS21030	COG3206	protein involved in exopolysaccharide biosynthesis
I6H86_RS21030	COG0489	protein tyrosine kinase activity
I6H86_RS21035	COG0463	Glycosyl transferase, family 2
I6H86_RS21040	COG1045	serine acetyltransferase
I6H86_RS21045	COG0438	transferase activity, transferring glycosyl groups
I6H86_RS21055	COG1216	Glycosyl transferase, family 2
I6H86_RS21060	COG0110	maltose O-acetyltransferase activity
I6H86_RS21065	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
I6H86_RS21070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6H86_RS21075	COG1051	belongs to the nudix hydrolase family
I6H86_RS21080	COG0297	glycogen (starch) synthase activity
I6H86_RS21090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I6H86_RS21095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
I6H86_RS21100	COG2244	polysaccharide biosynthetic process
I6H86_RS21105	COG2327	Polysaccharide pyruvyl transferase
I6H86_RS21165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
I6H86_RS21190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
I6H86_RS21220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
I6H86_RS21225	COG0583	DNA-binding transcription factor activity
I6H86_RS21235	COG0531	amino acid
I6H86_RS21240	COG2925	Exonuclease
I6H86_RS21255	COG1289	transmembrane transporter activity
I6H86_RS21290	COG4656	Part of a membrane complex involved in electron transport
I6H86_RS21295	COG1454	alcohol dehydrogenase
I6H86_RS21295	COG1012	belongs to the aldehyde dehydrogenase family
I6H86_RS21310	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
I6H86_RS21485	COG0583	DNA-binding transcription factor activity
I6H86_RS21520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
I6H86_RS21525	COG4106	trans-aconitate 2-methyltransferase activity
I6H86_RS21545	COG0534	Mate efflux family protein
I6H86_RS21555	COG3122	Protein conserved in bacteria
I6H86_RS21570	COG1733	regulation of RNA biosynthetic process
I6H86_RS21595	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
I6H86_RS21600	COG0477	Major facilitator Superfamily
I6H86_RS21605	COG1120	ATPase activity
I6H86_RS21615	COG4139	cobalamin transport
I6H86_RS21635	COG2197	response regulator
I6H86_RS21650	COG1250	3-hydroxyacyl-CoA dehydrogenase
I6H86_RS21655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I6H86_RS21660	COG1960	acyl-CoA dehydrogenase activity
I6H86_RS21690	COG0154	amidase activity
I6H86_RS21715	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
I6H86_RS21765	COG3504	Conjugal transfer protein
I6H86_RS21845	COG4771	TonB-dependent receptor
I6H86_RS21850	COG1021	2,3-dihydroxybenzoate-AMP ligase
I6H86_RS21885	COG1132	(ABC) transporter
I6H86_RS21890	COG2814	Major facilitator Superfamily
I6H86_RS21895	COG1169	isochorismate synthase