locus-tag	class	description
CEP66_RS00010	COG0824	Thioesterase
CEP66_RS00015	COG3790	cyd operon protein YbgE
CEP66_RS00020	COG4890	Cyd operon protein YbgT
CEP66_RS00025	COG1294	oxidase, subunit
CEP66_RS00030	COG1271	oxidase subunit
CEP66_RS00035	COG0383	alpha-mannosidase activity
CEP66_RS00040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS00040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS00040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS00045	COG2188	Transcriptional regulator
CEP66_RS00050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CEP66_RS00060	COG4865	methylaspartate mutase activity
CEP66_RS00065	COG3799	methylaspartate ammonia-lyase activity
CEP66_RS00080	COG1301	dicarboxylic acid transport
CEP66_RS00085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS00085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS00095	COG0583	DNA-binding transcription factor activity
CEP66_RS00100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP66_RS00110	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEP66_RS00115	COG0567	Dehydrogenase, E1 component
CEP66_RS00125	COG1053	succinate dehydrogenase
CEP66_RS00130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CEP66_RS00135	COG2009	succinate dehydrogenase
CEP66_RS00150	COG3157	Type VI secretion system effector, Hcp
CEP66_RS00165	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
CEP66_RS00170	COG3180	Ammonia monooxygenase
CEP66_RS00185	COG2211	Major facilitator Superfamily
CEP66_RS00195	COG1917	Cupin 2, conserved barrel domain protein
CEP66_RS00195	COG4977	sequence-specific DNA binding
CEP66_RS00225	COG1984	allophanate hydrolase subunit 2
CEP66_RS00230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CEP66_RS00235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CEP66_RS00270	COG2205	protein histidine kinase activity
CEP66_RS00275	COG0745	RESPONSE REGULATOR receiver
CEP66_RS00285	COG1982	Orn Lys Arg decarboxylase major
CEP66_RS00290	COG0531	amino acid
CEP66_RS00295	COG0033	Phosphoglucomutase
CEP66_RS00300	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CEP66_RS00305	COG0596	Alpha beta hydrolase
CEP66_RS00325	COG0735	belongs to the Fur family
CEP66_RS00350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS00350	COG1263	PTS System
CEP66_RS00350	COG2190	(PTS) system
CEP66_RS00360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEP66_RS00365	COG1940	carbohydrate kinase activity
CEP66_RS00365	COG1846	Transcriptional regulator
CEP66_RS00370	COG0647	UMP catabolic process
CEP66_RS00375	COG0367	asparagine synthase
CEP66_RS00415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEP66_RS00425	COG1702	phosphate starvation-inducible protein PhoH
CEP66_RS00435	COG4535	Mg2 and Co2 transporter CorC
CEP66_RS00450	COG0765	amino acid transport
CEP66_RS00455	COG0765	amino acid transport
CEP66_RS00460	COG1126	abc transporter atp-binding protein
CEP66_RS00470	COG2888	peptidyl-tyrosine sulfation
CEP66_RS00485	COG1466	dna polymerase III delta subunit
CEP66_RS00495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CEP66_RS00505	COG0799	negative regulation of ribosome biogenesis
CEP66_RS00515	COG0768	penicillin binding
CEP66_RS00520	COG0772	Belongs to the SEDS family
CEP66_RS00525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEP66_RS00530	COG1686	Belongs to the peptidase S11 family
CEP66_RS00545	COG0583	DNA-binding transcription factor activity
CEP66_RS00560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEP66_RS00580	COG3069	C4-dicarboxylate transmembrane transporter activity
CEP66_RS00585	COG4565	transcriptional regulatory protein
CEP66_RS00590	COG3290	protein histidine kinase activity
CEP66_RS00595	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CEP66_RS00605	COG2301	Belongs to the HpcH HpaI aldolase family
CEP66_RS00610	COG3051	citrate lyase alpha subunit
CEP66_RS00625	COG0471	metal ion transport
CEP66_RS00630	COG3719	Belongs to the RNase T2 family
CEP66_RS00635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEP66_RS00650	COG3634	alkyl hydroperoxide reductase activity
CEP66_RS00660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEP66_RS00665	COG0583	DNA-binding transcription factor activity
CEP66_RS00670	COG3969	phosphoadenosine phosphosulfate
CEP66_RS00675	COG1475	DNA binding
CEP66_RS00680	COG0436	Aminotransferase
CEP66_RS00685	COG0371	Dehydrogenase
CEP66_RS00695	COG2879	small protein
CEP66_RS00700	COG1966	Carbon starvation protein
CEP66_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS00715	COG1535	isochorismatase
CEP66_RS00715	COG3433	isochorismatase activity
CEP66_RS00720	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEP66_RS00725	COG1169	isochorismate synthase
CEP66_RS00730	COG4592	Periplasmic binding protein
CEP66_RS00740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS00745	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS00750	COG1120	ATPase activity
CEP66_RS00755	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
CEP66_RS00760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEP66_RS00760	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CEP66_RS00765	COG3251	PFAM MbtH domain protein
CEP66_RS00770	COG2382	esterase
CEP66_RS00775	COG4771	TonB-dependent receptor
CEP66_RS00780	COG2977	Belongs to the P-Pant transferase superfamily
CEP66_RS00785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CEP66_RS00825	COG4774	siderophore transport
CEP66_RS00845	COG2315	Protein conserved in bacteria
CEP66_RS00860	COG0477	Major facilitator Superfamily
CEP66_RS00865	COG0668	transmembrane transport
CEP66_RS00870	COG1609	Transcriptional regulator
CEP66_RS00885	COG2211	Major facilitator Superfamily
CEP66_RS00890	COG1113	amino acid transport
CEP66_RS00910	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP66_RS00915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS00920	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS00925	COG1538	Outer membrane efflux protein
CEP66_RS00930	COG0745	RESPONSE REGULATOR receiver
CEP66_RS00935	COG5002	protein histidine kinase activity
CEP66_RS01005	COG2501	S4 domain
CEP66_RS01015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CEP66_RS01030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CEP66_RS01035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CEP66_RS01045	COG2011	ABC-type metal ion transport system permease component
CEP66_RS01055	COG1464	Belongs to the NlpA lipoprotein family
CEP66_RS01065	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CEP66_RS01070	COG4181	ATPase activity
CEP66_RS01075	COG2755	lipolytic protein G-D-S-L family
CEP66_RS01080	COG0300	oxidoreductase activity
CEP66_RS01085	COG3118	belongs to the thioredoxin family
CEP66_RS01090	COG0390	transport system, permease component
CEP66_RS01095	COG4619	ABC transporter
CEP66_RS01100	COG0330	HflC and HflK could
CEP66_RS01105	COG1585	Membrane protein implicated in regulation of membrane protease activity
CEP66_RS01115	COG4771	TonB-dependent receptor
CEP66_RS01120	COG4558	Periplasmic binding protein
CEP66_RS01130	COG3721	Heme iron utilization protein
CEP66_RS01140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS01150	COG0477	Major facilitator Superfamily
CEP66_RS01155	COG1609	Transcriptional regulator
CEP66_RS01165	COG1285	pathogenesis
CEP66_RS01170	COG2217	Heavy metal translocating P-type atpase
CEP66_RS01175	COG3735	TraB family
CEP66_RS01180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEP66_RS01190	COG2223	nitrite transmembrane transporter activity
CEP66_RS01195	COG4651	solute:proton antiporter activity
CEP66_RS01195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CEP66_RS01205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS01265	COG2832	Protein of unknown function (DUF454)
CEP66_RS01270	COG3923	Primosomal replication protein n
CEP66_RS01280	COG5464	transposase or invertase
CEP66_RS01285	COG3264	Mechanosensitive ion channel
CEP66_RS01285	COG1196	nuclear chromosome segregation
CEP66_RS01290	COG1309	transcriptional regulator
CEP66_RS01295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS01300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP66_RS01315	COG0110	maltose O-acetyltransferase activity
CEP66_RS01325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CEP66_RS01335	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEP66_RS01340	COG5507	3-demethylubiquinone-9 3-methyltransferase
CEP66_RS01345	COG2364	Membrane
CEP66_RS01350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP66_RS01390	COG3695	enzyme binding
CEP66_RS01395	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CEP66_RS01400	COG1946	Acyl-CoA thioesterase
CEP66_RS01405	COG0004	ammonium transporteR
CEP66_RS01410	COG0347	Belongs to the P(II) protein family
CEP66_RS01420	COG1132	(ABC) transporter
CEP66_RS01425	COG1132	(ABC) transporter
CEP66_RS01430	COG1522	sequence-specific DNA binding
CEP66_RS01445	COG4533	DNA binding
CEP66_RS01455	COG0824	Thioesterase
CEP66_RS01460	COG1555	photosystem II stabilization
CEP66_RS01465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEP66_RS01470	COG0776	regulation of translation
CEP66_RS01475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CEP66_RS01500	COG0271	Belongs to the BolA IbaG family
CEP66_RS01510	COG3056	Lipoprotein
CEP66_RS01515	COG2223	nitrite transmembrane transporter activity
CEP66_RS01520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CEP66_RS01525	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CEP66_RS01530	COG1845	cytochrome c oxidase, subunit III
CEP66_RS01535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CEP66_RS01545	COG2814	Major facilitator Superfamily
CEP66_RS01575	COG0142	geranyltranstransferase activity
CEP66_RS01585	COG0667	Aldo Keto reductase
CEP66_RS01590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CEP66_RS01595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CEP66_RS01610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEP66_RS01610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CEP66_RS01620	COG4238	major outer membrane lipoprotein
CEP66_RS01625	COG3248	Nucleoside-binding outer membrane protein
CEP66_RS01635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEP66_RS01640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CEP66_RS01645	COG1862	Preprotein translocase
CEP66_RS01665	COG0450	alkyl hydroperoxide reductase
CEP66_RS01680	COG0583	DNA-binding transcription factor activity
CEP66_RS01685	COG0366	Alpha amylase catalytic
CEP66_RS01700	COG5002	protein histidine kinase activity
CEP66_RS01710	COG0420	3'-5' exonuclease activity
CEP66_RS01715	COG0419	ATPase involved in DNA repair
CEP66_RS01720	COG1940	carbohydrate kinase activity
CEP66_RS01735	COG4126	flavin adenine dinucleotide binding
CEP66_RS01755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CEP66_RS01760	COG3706	GGDEF domain
CEP66_RS01770	COG1785	Belongs to the alkaline phosphatase family
CEP66_RS01780	COG1609	Transcriptional regulator
CEP66_RS01785	COG2271	Major facilitator Superfamily
CEP66_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS01825	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CEP66_RS01830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEP66_RS01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEP66_RS01845	COG0113	porphobilinogen synthase activity
CEP66_RS01855	COG2175	clavaminate synthase activity
CEP66_RS01860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEP66_RS01865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CEP66_RS01870	COG4521	taurine ABC transporter
CEP66_RS01885	COG2271	Major facilitator Superfamily
CEP66_RS01890	COG1840	ABC-type Fe3 transport system, periplasmic component
CEP66_RS01900	COG3842	ATPase activity
CEP66_RS01910	COG2040	homocysteine
CEP66_RS01915	COG1609	Transcriptional regulator
CEP66_RS01945	COG3829	transcription factor binding
CEP66_RS01955	COG1280	lysine exporter protein (LysE YggA)
CEP66_RS01960	COG2814	Major facilitator Superfamily
CEP66_RS01970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP66_RS01975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS01985	COG1737	Transcriptional regulator
CEP66_RS01995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS02000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS02005	COG1120	ATPase activity
CEP66_RS02010	COG4774	siderophore transport
CEP66_RS02025	COG0814	amino acid
CEP66_RS02040	COG0791	NLP P60 protein
CEP66_RS02050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CEP66_RS02055	COG1191	sigma factor activity
CEP66_RS02080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CEP66_RS02085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEP66_RS02090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEP66_RS02115	COG1256	bacterial-type flagellum assembly
CEP66_RS02115	COG4786	Flagellar basal body rod
CEP66_RS02125	COG1706	bacterial-type flagellum-dependent cell motility
CEP66_RS02135	COG4786	Flagellar basal body rod
CEP66_RS02155	COG1558	bacterial-type flagellum-dependent cell motility
CEP66_RS02160	COG1815	bacterial-type flagellum-dependent cell motility
CEP66_RS02180	COG2226	methyltransferase
CEP66_RS02185	COG1216	Glycosyl transferase, family 2
CEP66_RS02185	COG1442	glycosyl transferase family 8
CEP66_RS02220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CEP66_RS02255	COG1987	bacterial-type flagellum assembly
CEP66_RS02260	COG1684	flagellar biosynthetic protein fliR
CEP66_RS02285	COG2200	EAL domain
CEP66_RS02310	COG2207	Transcriptional regulator
CEP66_RS02330	COG3188	usher protein
CEP66_RS02360	COG1732	Glycine betaine
CEP66_RS02365	COG2986	histidine ammonia-lyase
CEP66_RS02410	COG0411	ABC transporter
CEP66_RS02460	COG2003	Belongs to the UPF0758 family
CEP66_RS02495	COG2378	regulation of single-species biofilm formation
CEP66_RS02505	COG3596	GTP binding
CEP66_RS02525	COG2814	Major facilitator Superfamily
CEP66_RS02530	COG0778	Nitroreductase
CEP66_RS02540	COG0667	Aldo Keto reductase
CEP66_RS02550	COG5002	protein histidine kinase activity
CEP66_RS02575	COG2814	Major facilitator Superfamily
CEP66_RS02580	COG1522	sequence-specific DNA binding
CEP66_RS02595	COG0583	DNA-binding transcription factor activity
CEP66_RS02615	COG0656	L-ascorbic acid biosynthetic process
CEP66_RS02620	COG0667	Aldo Keto reductase
CEP66_RS02630	COG0702	epimerase
CEP66_RS02660	COG0582	viral genome integration into host DNA
CEP66_RS02680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEP66_RS02700	COG2195	Cleaves the N-terminal amino acid of tripeptides
CEP66_RS02710	COG3034	peptidoglycan biosynthetic process
CEP66_RS02715	COG0121	glutamine amidotransferase
CEP66_RS02725	COG1960	acyl-CoA dehydrogenase activity
CEP66_RS02730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEP66_RS02750	COG2226	methyltransferase
CEP66_RS02760	COG1388	LysM domain
CEP66_RS02760	COG0741	lytic transglycosylase activity
CEP66_RS02765	COG2226	methyltransferase
CEP66_RS02775	COG0583	DNA-binding transcription factor activity
CEP66_RS02810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CEP66_RS02825	COG1464	Belongs to the NlpA lipoprotein family
CEP66_RS02835	COG1720	tRNA m6t6A37 methyltransferase activity
CEP66_RS02845	COG3015	lipoprotein NlpE involved in copper resistance
CEP66_RS02850	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CEP66_RS02865	COG4568	rho-dependent transcription termination
CEP66_RS02875	COG0346	lactoylglutathione lyase activity
CEP66_RS02880	COG1982	Orn Lys Arg decarboxylase major
CEP66_RS02920	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CEP66_RS02935	COG0575	Belongs to the CDS family
CEP66_RS02945	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CEP66_RS02990	COG3835	regulator
CEP66_RS02995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP66_RS03020	COG2860	membrane
CEP66_RS03045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP66_RS03050	COG1120	ATPase activity
CEP66_RS03055	COG4774	siderophore transport
CEP66_RS03060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CEP66_RS03065	COG1643	Atp-dependent helicase
CEP66_RS03070	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CEP66_RS03090	COG0617	tRNA 3'-terminal CCA addition
CEP66_RS03095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CEP66_RS03120	COG3121	Chaperone
CEP66_RS03125	COG3188	usher protein
CEP66_RS03150	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS03155	COG0842	Transport permease protein
CEP66_RS03160	COG1131	(ABC) transporter
CEP66_RS03165	COG0288	reversible hydration of carbon dioxide
CEP66_RS03170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CEP66_RS03175	COG4993	Dehydrogenase
CEP66_RS03180	COG2132	Multicopper oxidase
CEP66_RS03215	COG3064	Membrane
CEP66_RS03225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP66_RS03230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CEP66_RS03235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CEP66_RS03245	COG1113	amino acid transport
CEP66_RS03250	COG2211	Major facilitator Superfamily
CEP66_RS03255	COG3940	Belongs to the glycosyl hydrolase 43 family
CEP66_RS03260	COG3725	Membrane protein required for beta-lactamase induction
CEP66_RS03275	COG4969	Belongs to the N-Me-Phe pilin family
CEP66_RS03280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CEP66_RS03285	COG1459	type II secretion system
CEP66_RS03310	COG0494	nUDIX hydrolase
CEP66_RS03330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CEP66_RS03335	COG0849	cell division
CEP66_RS03345	COG1181	Belongs to the D-alanine--D-alanine ligase family
CEP66_RS03360	COG0772	Belongs to the SEDS family
CEP66_RS03375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CEP66_RS03380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CEP66_RS03385	COG0768	penicillin binding
CEP66_RS03405	COG1609	Transcriptional regulator
CEP66_RS03415	COG0028	Belongs to the TPP enzyme family
CEP66_RS03450	COG2814	Major facilitator Superfamily
CEP66_RS03470	COG1178	ABC-type Fe3 transport system permease component
CEP66_RS03480	COG0586	Pfam SNARE associated Golgi protein
CEP66_RS03500	COG0235	Class ii aldolase
CEP66_RS03505	COG0417	DNA replication proofreading
CEP66_RS03515	COG0564	pseudouridine synthase activity
CEP66_RS03520	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CEP66_RS03535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEP66_RS03585	COG2271	Major facilitator Superfamily
CEP66_RS03595	COG0644	oxidoreductase
CEP66_RS03680	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEP66_RS03685	COG3493	citrate carrier protein
CEP66_RS03710	COG1047	Peptidyl-prolyl cis-trans
CEP66_RS03725	COG0196	riboflavin kinase activity
CEP66_RS03740	COG0583	DNA-binding transcription factor activity
CEP66_RS03760	COG1584	GPR1 FUN34 yaaH family protein
CEP66_RS03770	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEP66_RS03780	COG1115	amino acid carrier protein
CEP66_RS03795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CEP66_RS03805	COG0527	aspartate kinase activity
CEP66_RS03805	COG0460	homoserine dehydrogenase
CEP66_RS03815	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CEP66_RS03825	COG0745	RESPONSE REGULATOR receiver
CEP66_RS03830	COG3045	CreA protein
CEP66_RS03835	COG3708	Transcriptional regulator
CEP66_RS03835	COG2207	Transcriptional regulator
CEP66_RS03855	COG0741	lytic transglycosylase activity
CEP66_RS03865	COG0488	(ABC) transporter
CEP66_RS03880	COG0560	Phosphoserine phosphatase
CEP66_RS03885	COG3726	membrane protein affecting hemolysin expression
CEP66_RS03900	COG3121	Chaperone
CEP66_RS03905	COG3188	usher protein
CEP66_RS03925	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CEP66_RS03935	COG1328	CTP reductase activity
CEP66_RS03940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEP66_RS03945	COG0084	hydrolase, TatD family'
CEP66_RS03950	COG4667	esterase of the alpha-beta hydrolase superfamily
CEP66_RS03960	COG2823	Periplasmic or secreted lipoprotein
CEP66_RS03970	COG1011	Hydrolase
CEP66_RS03975	COG0456	acetyltransferase
CEP66_RS03980	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
CEP66_RS04010	COG3706	GGDEF domain
CEP66_RS04015	COG4114	ferric iron reductase
CEP66_RS04020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP66_RS04025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEP66_RS04030	COG2197	response regulator
CEP66_RS04035	COG2197	response regulator
CEP66_RS04040	COG2966	Psort location CytoplasmicMembrane, score
CEP66_RS04055	COG1484	DNA-dependent DNA replication
CEP66_RS04075	COG0840	transmembrane signaling receptor activity
CEP66_RS04085	COG1966	Carbon starvation protein
CEP66_RS04090	COG2879	small protein
CEP66_RS04095	COG0523	cobalamin synthesis protein
CEP66_RS04105	COG1566	PFAM secretion protein HlyD family protein
CEP66_RS04115	COG5457	Domain of unknown function (DUF1127)
CEP66_RS04120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP66_RS04125	COG5464	transposase or invertase
CEP66_RS04135	COG0626	cystathionine gamma-synthase activity
CEP66_RS04140	COG1301	dicarboxylic acid transport
CEP66_RS04145	COG0583	DNA-binding transcription factor activity
CEP66_RS04150	COG2733	membrane
CEP66_RS04155	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CEP66_RS04160	COG1924	4 iron, 4 sulfur cluster binding
CEP66_RS04170	COG0477	Major facilitator Superfamily
CEP66_RS04175	COG0180	Tryptophanyl-tRNA synthetase
CEP66_RS04365	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CEP66_RS04380	COG3423	Transcriptional regulator
CEP66_RS04395	COG3732	PTS system glucitol sorbitol-specific
CEP66_RS04400	COG0673	inositol 2-dehydrogenase activity
CEP66_RS04430	COG3121	Chaperone
CEP66_RS04500	COG3177	Filamentation induced by cAMP protein fic
CEP66_RS04520	COG0582	viral genome integration into host DNA
CEP66_RS04530	COG1064	alcohol dehydrogenase
CEP66_RS04535	COG0433	COG0433 Predicted ATPase
CEP66_RS04540	COG0795	lipopolysaccharide-transporting ATPase activity
CEP66_RS04545	COG0795	lipopolysaccharide-transporting ATPase activity
CEP66_RS04560	COG2927	DNA polymerase III (CHI subunit)
CEP66_RS04565	COG0525	valine-tRNA ligase activity
CEP66_RS04595	COG2731	YhcH YjgK YiaL family protein
CEP66_RS04605	COG2235	arginine
CEP66_RS04615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CEP66_RS04620	COG1288	antiporter activity
CEP66_RS04625	COG1438	arginine binding
CEP66_RS04680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS04680	COG1263	PTS System
CEP66_RS04685	COG0366	Alpha amylase catalytic
CEP66_RS04695	COG1737	Transcriptional regulator
CEP66_RS04705	COG0383	alpha-mannosidase activity
CEP66_RS04710	COG0366	Alpha amylase catalytic
CEP66_RS04715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS04715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS04715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS04725	COG0602	queuosine metabolic process
CEP66_RS04730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS04730	COG3711	transcriptional antiterminator
CEP66_RS04745	COG3964	amidohydrolase
CEP66_RS04775	COG0312	modulator of DNA gyrase
CEP66_RS04790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CEP66_RS04800	COG0840	transmembrane signaling receptor activity
CEP66_RS04805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS04810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS04815	COG1129	ABC transporter
CEP66_RS04820	COG1879	ABC-type sugar transport system periplasmic component
CEP66_RS04835	COG3157	Type VI secretion system effector, Hcp
CEP66_RS04840	COG2105	PFAM AIG2 family protein
CEP66_RS04845	COG2911	Protein conserved in bacteria
CEP66_RS04850	COG0729	surface antigen
CEP66_RS04860	COG1253	flavin adenine dinucleotide binding
CEP66_RS04870	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CEP66_RS04875	COG1218	3'(2'),5'-bisphosphate nucleotidase
CEP66_RS04885	COG1733	regulation of RNA biosynthetic process
CEP66_RS04890	COG0702	epimerase
CEP66_RS04900	COG0697	spore germination
CEP66_RS04915	COG1113	amino acid transport
CEP66_RS04920	COG0545	Peptidyl-prolyl cis-trans isomerase
CEP66_RS04925	COG3061	Opacity-associated protein A
CEP66_RS04940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CEP66_RS04975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS04980	COG3414	Phosphotransferase system galactitol-specific IIB component
CEP66_RS05000	COG1073	alpha beta
CEP66_RS05005	COG3650	response to hydrogen peroxide
CEP66_RS05015	COG1960	acyl-CoA dehydrogenase activity
CEP66_RS05020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP66_RS05045	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CEP66_RS05050	COG0330	HflC and HflK could
CEP66_RS05055	COG0330	HflC and HflK could
CEP66_RS05060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CEP66_RS05080	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP66_RS05085	COG0802	atpase or kinase
CEP66_RS05090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CEP66_RS05090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CEP66_RS05095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEP66_RS05135	COG3264	Mechanosensitive ion channel
CEP66_RS05135	COG1511	domain protein
CEP66_RS05150	COG1053	succinate dehydrogenase
CEP66_RS05155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CEP66_RS05200	COG1509	lysine 2,3-aminomutase activity
CEP66_RS05230	COG0531	amino acid
CEP66_RS05235	COG3030	protein affecting phage T7 exclusion by the F plasmid
CEP66_RS05245	COG1027	Aspartate ammonia-lyase
CEP66_RS05250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEP66_RS05265	COG1309	transcriptional regulator
CEP66_RS05315	COG0582	viral genome integration into host DNA
CEP66_RS05320	COG4974	Belongs to the 'phage' integrase family
CEP66_RS05330	COG3539	Fimbrial protein
CEP66_RS05335	COG3121	Chaperone
CEP66_RS05340	COG3188	usher protein
CEP66_RS05345	COG3539	Fimbrial protein
CEP66_RS05350	COG3539	Fimbrial protein
CEP66_RS05355	COG3539	Fimbrial protein
CEP66_RS05365	COG0840	transmembrane signaling receptor activity
CEP66_RS05370	COG0281	malic enzyme
CEP66_RS05375	COG3069	C4-dicarboxylate transmembrane transporter activity
CEP66_RS05380	COG1737	Transcriptional regulator
CEP66_RS05385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEP66_RS05405	COG1609	Transcriptional regulator
CEP66_RS05415	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS05420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CEP66_RS05430	COG0246	Mannitol dehydrogenase
CEP66_RS05440	COG1904	glucuronate isomerase
CEP66_RS05445	COG1312	Catalyzes the dehydration of D-mannonate
CEP66_RS05460	COG4771	TonB-dependent receptor
CEP66_RS05465	COG3720	iron ion transport
CEP66_RS05470	COG4558	Periplasmic binding protein
CEP66_RS05475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS05485	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CEP66_RS05490	COG3290	protein histidine kinase activity
CEP66_RS05495	COG4565	transcriptional regulatory protein
CEP66_RS05500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CEP66_RS05505	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS05505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS05550	COG2824	Alkylphosphonate utilization operon protein PhnA
CEP66_RS05555	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CEP66_RS05560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CEP66_RS05565	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CEP66_RS05570	COG3639	organic phosphonate transmembrane transporter activity
CEP66_RS05575	COG2188	Transcriptional regulator
CEP66_RS05580	COG3624	Phosphonate C-P lyase system protein PhnG
CEP66_RS05585	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CEP66_RS05590	COG3626	phosphonate metabolism
CEP66_RS05595	COG3627	carbon phosphorus lyase activity
CEP66_RS05600	COG4107	phosphonate C-P lyase system protein PhnK
CEP66_RS05605	COG4778	phosphonate C-P lyase system protein PhnL
CEP66_RS05610	COG3454	Phosphonate metabolism
CEP66_RS05615	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CEP66_RS05620	COG0456	acetyltransferase
CEP66_RS05625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CEP66_RS05635	COG0698	ribose 5-phosphate isomerase
CEP66_RS05640	COG1737	Transcriptional regulator
CEP66_RS05645	COG1879	ABC-type sugar transport system periplasmic component
CEP66_RS05650	COG1129	ABC transporter
CEP66_RS05655	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS05660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEP66_RS05665	COG1940	carbohydrate kinase activity
CEP66_RS05670	COG0784	Response regulator, receiver
CEP66_RS05670	COG4191	Histidine kinase
CEP66_RS05680	COG1129	ABC transporter
CEP66_RS05685	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS05705	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CEP66_RS05705	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CEP66_RS05720	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CEP66_RS05725	COG1301	dicarboxylic acid transport
CEP66_RS05730	COG4235	cytochrome complex assembly
CEP66_RS05735	COG3088	subunit of a heme lyase
CEP66_RS05740	COG1138	Cytochrome C-type biogenesis protein
CEP66_RS05745	COG3301	Polysulphide reductase, NrfD
CEP66_RS05750	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS05755	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CEP66_RS05775	COG3162	membrane
CEP66_RS05785	COG1346	cytolysis
CEP66_RS05790	COG1380	Effector of murein hydrolase LrgA
CEP66_RS05795	COG0583	DNA-binding transcription factor activity
CEP66_RS05800	COG1943	Transposase
CEP66_RS05805	COG0025	NhaP-type Na H and K H
CEP66_RS05810	COG2252	PERMEase
CEP66_RS05835	COG0789	Transcriptional regulator
CEP66_RS05845	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CEP66_RS05860	COG1595	DNA-templated transcription, initiation
CEP66_RS05865	COG3712	iron ion homeostasis
CEP66_RS05870	COG4772	TonB-dependent receptor
CEP66_RS05875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CEP66_RS05880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS05885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS05890	COG1120	ATPase activity
CEP66_RS05895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CEP66_RS05905	COG0589	response to stress
CEP66_RS05910	COG0629	single-stranded DNA binding
CEP66_RS05925	COG2315	Protein conserved in bacteria
CEP66_RS05930	COG3700	Belongs to the class B bacterial acid phosphatase family
CEP66_RS05935	COG1448	Aminotransferase
CEP66_RS05940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEP66_RS05960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEP66_RS05975	COG3157	Type VI secretion system effector, Hcp
CEP66_RS05980	COG0735	belongs to the Fur family
CEP66_RS05985	COG3237	CsbD-like
CEP66_RS05990	COG0534	Mate efflux family protein
CEP66_RS06000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CEP66_RS06050	COG3833	ABC-type maltose transport systems, permease component
CEP66_RS06055	COG3223	Belongs to the PsiE family
CEP66_RS06065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEP66_RS06095	COG0527	aspartate kinase activity
CEP66_RS06110	COG1187	pseudouridine synthase activity
CEP66_RS06125	COG0646	methionine synthase
CEP66_RS06125	COG1410	methionine synthase
CEP66_RS06145	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CEP66_RS06155	COG0456	acetyltransferase
CEP66_RS06185	COG0151	Belongs to the GarS family
CEP66_RS06220	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CEP66_RS06235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CEP66_RS06240	COG2104	thiamine diphosphate biosynthetic process
CEP66_RS06265	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP66_RS06305	COG0250	Participates in transcription elongation, termination and antitermination
CEP66_RS06310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEP66_RS06355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CEP66_RS06420	COG0583	DNA-binding transcription factor activity
CEP66_RS06455	COG2207	Transcriptional regulator
CEP66_RS06460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS06465	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEP66_RS06470	COG1882	Formate acetyltransferase
CEP66_RS06475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS06480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS06485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEP66_RS06485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS06485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS06495	COG0371	Dehydrogenase
CEP66_RS06510	COG0583	DNA-binding transcription factor activity
CEP66_RS06520	COG0527	aspartate kinase activity
CEP66_RS06520	COG0460	homoserine dehydrogenase
CEP66_RS06525	COG0626	cystathionine gamma-synthase activity
CEP66_RS06540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CEP66_RS06545	COG1609	Transcriptional regulator
CEP66_RS06550	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CEP66_RS06565	COG1575	Belongs to the MenA family. Type 1 subfamily
CEP66_RS06580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CEP66_RS06590	COG1494	fructose-1,6-bisphosphatase
CEP66_RS06600	COG3152	Membrane
CEP66_RS06625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CEP66_RS06640	COG3678	ATP-independent chaperone mediated protein folding
CEP66_RS06645	COG0745	RESPONSE REGULATOR receiver
CEP66_RS06650	COG2205	protein histidine kinase activity
CEP66_RS06655	COG2258	MOSC domain
CEP66_RS06660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP66_RS06705	COG1454	alcohol dehydrogenase
CEP66_RS06720	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CEP66_RS06745	COG3188	usher protein
CEP66_RS06750	COG3121	Chaperone
CEP66_RS06760	COG3383	formate dehydrogenase (NAD+) activity
CEP66_RS06760	COG0243	molybdopterin cofactor binding
CEP66_RS06765	COG0243	molybdopterin cofactor binding
CEP66_RS06765	COG3383	formate dehydrogenase (NAD+) activity
CEP66_RS06770	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS06775	COG2864	formate dehydrogenase
CEP66_RS06790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CEP66_RS06795	COG0456	acetyltransferase
CEP66_RS06810	COG1011	Hydrolase
CEP66_RS06820	COG1349	DNA-binding transcription factor activity
CEP66_RS06825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS06835	COG3684	Belongs to the aldolase LacD family
CEP66_RS06845	COG1501	Belongs to the glycosyl hydrolase 31 family
CEP66_RS06875	COG0174	glutamine synthetase
CEP66_RS06880	COG3852	Histidine kinase
CEP66_RS06895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEP66_RS06925	COG0204	Acyl-transferase
CEP66_RS06940	COG3084	Protein conserved in bacteria
CEP66_RS06945	COG0746	molybdenum cofactor guanylyltransferase activity
CEP66_RS06950	COG1763	Mo-molybdopterin cofactor biosynthetic process
CEP66_RS06990	COG1739	Uncharacterized protein family UPF0029
CEP66_RS07030	COG0805	protein transport
CEP66_RS07050	COG3165	ubiquinone biosynthetic process from chorismate
CEP66_RS07060	COG1322	Protein conserved in bacteria
CEP66_RS07080	COG0583	DNA-binding transcription factor activity
CEP66_RS07085	COG0697	spore germination
CEP66_RS07090	COG0561	phosphatase activity
CEP66_RS07100	COG1280	lysine exporter protein (LysE YggA)
CEP66_RS07105	COG1280	lysine exporter protein (LysE YggA)
CEP66_RS07145	COG1011	Hydrolase
CEP66_RS07155	COG3159	Protein conserved in bacteria
CEP66_RS07190	COG2959	enzyme of heme biosynthesis
CEP66_RS07195	COG3071	HemY protein
CEP66_RS07240	COG2244	polysaccharide biosynthetic process
CEP66_RS07245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEP66_RS07250	COG0456	acetyltransferase
CEP66_RS07255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CEP66_RS07260	COG1088	dTDP-glucose 4,6-dehydratase activity
CEP66_RS07265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CEP66_RS07290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CEP66_RS07295	COG3118	belongs to the thioredoxin family
CEP66_RS07330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CEP66_RS07340	COG0583	DNA-binding transcription factor activity
CEP66_RS07345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CEP66_RS07355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEP66_RS07360	COG3978	acetolactate synthase activity
CEP66_RS07380	COG0606	chelatase, subunit chli
CEP66_RS07385	COG3085	chromosome segregation
CEP66_RS07425	COG2186	Transcriptional regulator
CEP66_RS07430	COG0477	Major facilitator Superfamily
CEP66_RS07435	COG1609	Transcriptional regulator
CEP66_RS07440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS07450	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS07490	COG1522	sequence-specific DNA binding
CEP66_RS07495	COG0716	FMN binding
CEP66_RS07510	COG3312	ion transport
CEP66_RS07565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CEP66_RS07570	COG0573	inorganic phosphate transmembrane transporter activity
CEP66_RS07575	COG0581	inorganic phosphate transmembrane transporter activity
CEP66_RS07585	COG0704	Plays a role in the regulation of phosphate uptake
CEP66_RS07590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP66_RS07595	COG2252	PERMEase
CEP66_RS07600	COG0431	NADPH-dependent FMN reductase
CEP66_RS07605	COG2091	lysine biosynthetic process via aminoadipic acid
CEP66_RS07655	COG0592	DNA-directed DNA polymerase activity
CEP66_RS07670	COG0561	phosphatase activity
CEP66_RS07695	COG0823	Involved in the tonB-independent uptake of proteins
CEP66_RS07700	COG5645	(Lipo)protein
CEP66_RS07720	COG2188	Transcriptional regulator
CEP66_RS07735	COG2207	Transcriptional regulator
CEP66_RS07740	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CEP66_RS07745	COG3119	arylsulfatase activity
CEP66_RS07750	COG2149	membrane
CEP66_RS07760	COG0641	radical SAM
CEP66_RS07770	COG2610	gluconate transmembrane transporter activity
CEP66_RS07775	COG0583	DNA-binding transcription factor activity
CEP66_RS07785	COG2814	Major facilitator Superfamily
CEP66_RS07805	COG0028	Belongs to the TPP enzyme family
CEP66_RS07810	COG0440	acetolactate synthase activity
CEP66_RS07820	COG2197	response regulator
CEP66_RS07830	COG2271	Major facilitator Superfamily
CEP66_RS07840	COG0800	Aldolase
CEP66_RS07845	COG3734	2-keto-3-deoxy-galactonokinase
CEP66_RS07850	COG2271	Major facilitator Superfamily
CEP66_RS07855	COG2721	sulfolactate sulfo-lyase activity
CEP66_RS07860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CEP66_RS07865	COG1414	Transcriptional regulator
CEP66_RS07905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS07905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS07910	COG3715	PTS system
CEP66_RS07915	COG3716	PTS system mannose fructose sorbose family IID component
CEP66_RS07930	COG1464	Belongs to the NlpA lipoprotein family
CEP66_RS07940	COG3121	Chaperone
CEP66_RS07950	COG3539	Fimbrial protein
CEP66_RS07955	COG3121	Chaperone
CEP66_RS07965	COG0697	spore germination
CEP66_RS07970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CEP66_RS07975	COG0604	alcohol dehydrogenase
CEP66_RS07980	COG0583	DNA-binding transcription factor activity
CEP66_RS07995	COG2982	Protein involved in outer membrane biogenesis
CEP66_RS08000	COG2233	PERMEase
CEP66_RS08005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CEP66_RS08010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP66_RS08015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEP66_RS08035	COG2860	membrane
CEP66_RS08040	COG1561	YicC-like family, N-terminal region
CEP66_RS08070	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CEP66_RS08100	COG1519	Transferase
CEP66_RS08105	COG0438	transferase activity, transferring glycosyl groups
CEP66_RS08110	COG0515	serine threonine protein kinase
CEP66_RS08115	COG1442	glycosyl transferase family 8
CEP66_RS08120	COG1442	glycosyl transferase family 8
CEP66_RS08130	COG0859	PFAM glycosyl transferase family 9
CEP66_RS08135	COG1215	transferase activity, transferring glycosyl groups
CEP66_RS08140	COG3307	-O-antigen
CEP66_RS08145	COG0859	PFAM glycosyl transferase family 9
CEP66_RS08150	COG0859	PFAM glycosyl transferase family 9
CEP66_RS08160	COG0156	8-amino-7-oxononanoate synthase activity
CEP66_RS08175	COG1216	Glycosyl transferase, family 2
CEP66_RS08180	COG2861	carbohydrate metabolic process
CEP66_RS08185	COG4942	peptidase
CEP66_RS08195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEP66_RS08200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CEP66_RS08215	COG1045	serine acetyltransferase
CEP66_RS08220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CEP66_RS08230	COG2186	Transcriptional regulator
CEP66_RS08250	COG3722	fumarate hydratase activity
CEP66_RS08260	COG2213	PTS system mannitol-specific
CEP66_RS08260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS08270	COG1566	PFAM secretion protein HlyD family protein
CEP66_RS08275	COG0625	glutathione transferase activity
CEP66_RS08285	COG3276	selenocysteine insertion sequence binding
CEP66_RS08290	COG1454	alcohol dehydrogenase
CEP66_RS08295	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS08305	COG0235	Class ii aldolase
CEP66_RS08310	COG3623	hexulose-6-phosphate isomerase
CEP66_RS08315	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CEP66_RS08320	COG1070	Carbohydrate kinase
CEP66_RS08335	COG2731	YhcH YjgK YiaL family protein
CEP66_RS08345	COG1414	Transcriptional regulator
CEP66_RS08350	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS08355	COG3977	Valine--pyruvate aminotransferase
CEP66_RS08360	COG0366	Alpha amylase catalytic
CEP66_RS08370	COG2992	FlgJ-related protein
CEP66_RS08375	COG1609	Transcriptional regulator
CEP66_RS08375	COG2207	Transcriptional regulator
CEP66_RS08380	COG4214	carbohydrate transport
CEP66_RS08390	COG4213	ABC transporter substrate-binding protein
CEP66_RS08400	COG1070	Carbohydrate kinase
CEP66_RS08410	COG3274	enterobacterial common antigen metabolic process
CEP66_RS08430	COG1278	Cold shock
CEP66_RS08435	COG2944	sequence-specific DNA binding
CEP66_RS08455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS08465	COG1609	Transcriptional regulator
CEP66_RS08470	COG2885	chlorophyll binding
CEP66_RS08475	COG0243	molybdopterin cofactor binding
CEP66_RS08480	COG0456	acetyltransferase
CEP66_RS08485	COG2818	Glycosylase
CEP66_RS08490	COG5571	outer membrane autotransporter
CEP66_RS08495	COG2223	nitrite transmembrane transporter activity
CEP66_RS08520	COG0747	negative chemotaxis
CEP66_RS08525	COG0601	transmembrane transport
CEP66_RS08530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEP66_RS08535	COG0444	Belongs to the ABC transporter superfamily
CEP66_RS08540	COG4608	Belongs to the ABC transporter superfamily
CEP66_RS08545	COG2204	response regulator
CEP66_RS08550	COG0814	amino acid
CEP66_RS08590	COG1215	transferase activity, transferring glycosyl groups
CEP66_RS08600	COG0457	Tetratricopeptide repeat
CEP66_RS08600	COG3118	belongs to the thioredoxin family
CEP66_RS08605	COG2199	diguanylate cyclase activity
CEP66_RS08605	COG2200	EAL domain
CEP66_RS08640	COG2200	EAL domain
CEP66_RS08645	COG2982	Protein involved in outer membrane biogenesis
CEP66_RS08650	COG0477	Major facilitator Superfamily
CEP66_RS08655	COG1295	ribonuclease BN
CEP66_RS08660	COG0583	DNA-binding transcription factor activity
CEP66_RS08680	COG1858	cytochrome C peroxidase
CEP66_RS08690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CEP66_RS08695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CEP66_RS08700	COG0339	signal peptide processing
CEP66_RS08715	COG1959	2 iron, 2 sulfur cluster binding
CEP66_RS08725	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CEP66_RS08735	COG0589	response to stress
CEP66_RS08750	COG0306	phosphate transporter
CEP66_RS08755	COG2081	HI0933 family
CEP66_RS08760	COG2239	Acts as a magnesium transporter
CEP66_RS08765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS08770	COG1129	ABC transporter
CEP66_RS08770	COG0842	Transport permease protein
CEP66_RS08775	COG0842	Transport permease protein
CEP66_RS08790	COG0444	Belongs to the ABC transporter superfamily
CEP66_RS08795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEP66_RS08800	COG0601	transmembrane transport
CEP66_RS08805	COG0747	negative chemotaxis
CEP66_RS08810	COG2091	lysine biosynthetic process via aminoadipic acid
CEP66_RS08815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEP66_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS08830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEP66_RS08855	COG1216	Glycosyl transferase, family 2
CEP66_RS08875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEP66_RS08885	COG0204	Acyl-transferase
CEP66_RS08905	COG0628	permease
CEP66_RS08910	COG0477	Major facilitator Superfamily
CEP66_RS08920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CEP66_RS08930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CEP66_RS08940	COG3714	YhhN family
CEP66_RS08965	COG3776	membrane
CEP66_RS08970	COG0742	ribosomal rna small subunit methyltransferase
CEP66_RS08975	COG0552	protein localization to endoplasmic reticulum
CEP66_RS08980	COG2884	Cell division ATP-binding protein ftsE
CEP66_RS08985	COG2177	Part of the ABC transporter FtsEX involved in
CEP66_RS08995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEP66_RS09000	COG0683	leucine binding
CEP66_RS09010	COG0683	leucine binding
CEP66_RS09020	COG4177	L-phenylalanine transmembrane transporter activity
CEP66_RS09025	COG0411	ABC transporter
CEP66_RS09030	COG0410	ABC transporter
CEP66_RS09055	COG0584	glycerophosphoryl diester phosphodiesterase
CEP66_RS09065	COG0405	Gamma-glutamyltransferase
CEP66_RS09085	COG1247	-acetyltransferase
CEP66_RS09090	COG0673	inositol 2-dehydrogenase activity
CEP66_RS09095	COG1741	Belongs to the pirin family
CEP66_RS09100	COG1609	Transcriptional regulator
CEP66_RS09105	COG3265	gluconokinase activity
CEP66_RS09110	COG2610	gluconate transmembrane transporter activity
CEP66_RS09115	COG2095	MarC family integral membrane protein
CEP66_RS09120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEP66_RS09145	COG0058	SHG alpha-glucan phosphorylase activity
CEP66_RS09185	COG3501	Rhs element vgr protein
CEP66_RS09190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEP66_RS09205	COG1349	DNA-binding transcription factor activity
CEP66_RS09240	COG0058	SHG alpha-glucan phosphorylase activity
CEP66_RS09245	COG1640	4-alpha-glucanotransferase
CEP66_RS09250	COG2610	gluconate transmembrane transporter activity
CEP66_RS09260	COG1040	competence protein
CEP66_RS09280	COG1918	ferrous iron import across plasma membrane
CEP66_RS09290	COG2183	response to ionizing radiation
CEP66_RS09295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CEP66_RS09330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CEP66_RS09335	COG1011	Hydrolase
CEP66_RS09345	COG0494	nUDIX hydrolase
CEP66_RS09350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CEP66_RS09355	COG4972	Pilus assembly protein
CEP66_RS09360	COG3166	PFAM Fimbrial assembly family protein
CEP66_RS09375	COG4796	Type ii and iii secretion system protein
CEP66_RS09395	COG3266	domain, Protein
CEP66_RS09400	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CEP66_RS09405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CEP66_RS09420	COG2188	Transcriptional regulator
CEP66_RS09430	COG3457	Alanine racemase
CEP66_RS09435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CEP66_RS09440	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CEP66_RS09455	COG0626	cystathionine gamma-synthase activity
CEP66_RS09485	COG2146	nitrite reductase [NAD(P)H] activity
CEP66_RS09490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEP66_RS09520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CEP66_RS09525	COG1289	transmembrane transporter activity
CEP66_RS09545	COG1765	OsmC-like protein
CEP66_RS09555	COG3954	Phosphoribulokinase
CEP66_RS09565	COG0429	hydrolase of the alpha beta-hydrolase fold
CEP66_RS09595	COG0679	Auxin Efflux Carrier
CEP66_RS09605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEP66_RS09615	COG0488	(ABC) transporter
CEP66_RS09630	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CEP66_RS09635	COG1047	Peptidyl-prolyl cis-trans
CEP66_RS09645	COG0545	Peptidyl-prolyl cis-trans isomerase
CEP66_RS09650	COG2964	Protein conserved in bacteria
CEP66_RS09710	COG0051	transcription antitermination factor activity, RNA binding
CEP66_RS09815	COG0201	protein transport
CEP66_RS09845	COG0203	ribosomal protein L17
CEP66_RS09855	COG0789	Transcriptional regulator
CEP66_RS09860	COG3036	rescue of stalled ribosome
CEP66_RS09890	COG0758	DNA mediated transformation
CEP66_RS09900	COG0551	DNA topoisomerase type I activity
CEP66_RS09920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEP66_RS09965	COG1126	abc transporter atp-binding protein
CEP66_RS09970	COG0765	amino acid transport
CEP66_RS09975	COG4597	amino acid ABC transporter
CEP66_RS09980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS09990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP66_RS09995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS10000	COG1309	transcriptional regulator
CEP66_RS10010	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CEP66_RS10035	COG4145	pantothenate transmembrane transporter activity
CEP66_RS10040	COG3924	membrane
CEP66_RS10045	COG0439	Biotin carboxylase
CEP66_RS10050	COG0511	ligase activity, forming carbon-carbon bonds
CEP66_RS10075	COG0604	alcohol dehydrogenase
CEP66_RS10080	COG2199	diguanylate cyclase activity
CEP66_RS10080	COG2200	EAL domain
CEP66_RS10090	COG1077	Cell shape determining protein MreB Mrl
CEP66_RS10095	COG1792	Involved in formation and maintenance of cell shape
CEP66_RS10100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CEP66_RS10115	COG3164	Protein of unknown function
CEP66_RS10120	COG0312	modulator of DNA gyrase
CEP66_RS10125	COG0583	DNA-binding transcription factor activity
CEP66_RS10145	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS10150	COG2732	(Barnase) inhibitor
CEP66_RS10170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP66_RS10175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CEP66_RS10180	COG3105	Protein conserved in bacteria
CEP66_RS10185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CEP66_RS10205	COG0625	glutathione transferase activity
CEP66_RS10210	COG2969	positive regulation of protein catabolic process
CEP66_RS10240	COG2731	YhcH YjgK YiaL family protein
CEP66_RS10245	COG4804	nuclease activity
CEP66_RS10250	COG0493	'glutamate synthase
CEP66_RS10255	COG0067	glutamate synthase
CEP66_RS10255	COG0069	glutamate synthase activity
CEP66_RS10255	COG0070	glutamate synthase
CEP66_RS10270	COG1242	4 iron, 4 sulfur cluster binding
CEP66_RS10275	COG5002	protein histidine kinase activity
CEP66_RS10275	COG2198	Histidine kinase
CEP66_RS10275	COG0784	Response regulator, receiver
CEP66_RS10280	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CEP66_RS10290	COG0515	serine threonine protein kinase
CEP66_RS10295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS10310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEP66_RS10320	COG1137	ATPase activity
CEP66_RS10325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CEP66_RS10330	COG3117	lipopolysaccharide transmembrane transporter activity
CEP66_RS10335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CEP66_RS10345	COG0530	calcium, potassium:sodium antiporter activity
CEP66_RS10350	COG1127	ABC transporter
CEP66_RS10355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CEP66_RS10360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEP66_RS10365	COG2854	intermembrane phospholipid transfer
CEP66_RS10370	COG3113	response to antibiotic
CEP66_RS10375	COG5007	Belongs to the BolA IbaG family
CEP66_RS10385	COG3423	Transcriptional regulator
CEP66_RS10390	COG0142	geranyltranstransferase activity
CEP66_RS10405	COG0697	spore germination
CEP66_RS10415	COG2027	D-alanyl-D-alanine carboxypeptidase
CEP66_RS10425	COG1534	Rna-binding protein
CEP66_RS10440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CEP66_RS10450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CEP66_RS10475	COG0195	Participates in both transcription termination and antitermination
CEP66_RS10495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CEP66_RS10510	COG0513	Belongs to the DEAD box helicase family
CEP66_RS10515	COG0814	amino acid
CEP66_RS10520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CEP66_RS10525	COG0826	peptidase U32
CEP66_RS10530	COG0826	peptidase U32
CEP66_RS10535	COG3154	lipid carrier protein
CEP66_RS10540	COG3153	acetyltransferase
CEP66_RS10555	COG0702	epimerase
CEP66_RS10560	COG0701	Predicted permease
CEP66_RS10565	COG2823	Periplasmic or secreted lipoprotein
CEP66_RS10585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CEP66_RS10600	COG1063	alcohol dehydrogenase
CEP66_RS10605	COG3775	system Galactitol-specific IIC component
CEP66_RS10610	COG3414	Phosphotransferase system galactitol-specific IIB component
CEP66_RS10615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS10630	COG2721	sulfolactate sulfo-lyase activity
CEP66_RS10640	COG2084	Dehydrogenase
CEP66_RS10645	COG1929	Belongs to the glycerate kinase type-1 family
CEP66_RS10655	COG0583	DNA-binding transcription factor activity
CEP66_RS10675	COG1882	Formate acetyltransferase
CEP66_RS10680	COG0251	oxidation-reduction process
CEP66_RS10685	COG1760	l-serine dehydratase
CEP66_RS10690	COG0814	amino acid
CEP66_RS10705	COG1741	Belongs to the pirin family
CEP66_RS10710	COG0583	DNA-binding transcription factor activity
CEP66_RS10715	COG3152	Membrane
CEP66_RS10720	COG0435	Glutathione S-transferase
CEP66_RS10735	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
CEP66_RS10740	COG4575	ribosome binding
CEP66_RS10745	COG1422	Protein of unknown function (DUF1090)
CEP66_RS10755	COG0586	Pfam SNARE associated Golgi protein
CEP66_RS10760	COG2186	Transcriptional regulator
CEP66_RS10765	COG2271	Major facilitator Superfamily
CEP66_RS10775	COG2721	sulfolactate sulfo-lyase activity
CEP66_RS10790	COG0673	inositol 2-dehydrogenase activity
CEP66_RS10795	COG1451	nucleotide metabolic process
CEP66_RS10805	COG0446	pyridine nucleotide-disulphide oxidoreductase
CEP66_RS10805	COG1902	pentaerythritol trinitrate reductase activity
CEP66_RS10810	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CEP66_RS10810	COG3408	Glycogen debranching enzyme
CEP66_RS10820	COG0531	amino acid
CEP66_RS10825	COG2731	YhcH YjgK YiaL family protein
CEP66_RS10830	COG3250	beta-galactosidase activity
CEP66_RS10835	COG1609	Transcriptional regulator
CEP66_RS10840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CEP66_RS10850	COG0840	transmembrane signaling receptor activity
CEP66_RS10860	COG1695	Transcriptional regulator
CEP66_RS10865	COG2375	cellular response to nickel ion
CEP66_RS10895	COG0582	viral genome integration into host DNA
CEP66_RS10935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEP66_RS10965	COG4695	Portal protein
CEP66_RS11130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CEP66_RS11185	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS11190	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS11205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEP66_RS11220	COG4991	sh3 domain protein
CEP66_RS11225	COG3025	triphosphatase activity
CEP66_RS11265	COG3384	dioxygenase
CEP66_RS11270	COG0754	glutathionylspermidine amidase activity
CEP66_RS11285	COG1538	Outer membrane efflux protein
CEP66_RS11290	COG0494	nUDIX hydrolase
CEP66_RS11295	COG3151	Protein conserved in bacteria
CEP66_RS11300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CEP66_RS11305	COG3150	esterase
CEP66_RS11325	COG2211	Major facilitator Superfamily
CEP66_RS11330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEP66_RS11335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CEP66_RS11340	COG2249	NAD(P)H dehydrogenase (quinone) activity
CEP66_RS11355	COG3111	PFAM Bacterial OB fold (BOF) protein
CEP66_RS11385	COG0656	L-ascorbic acid biosynthetic process
CEP66_RS11390	COG1979	alcohol dehydrogenase
CEP66_RS11395	COG2207	Transcriptional regulator
CEP66_RS11400	COG0586	Pfam SNARE associated Golgi protein
CEP66_RS11410	COG0626	cystathionine gamma-synthase activity
CEP66_RS11425	COG0848	biopolymer transport protein
CEP66_RS11445	COG0667	Aldo Keto reductase
CEP66_RS11455	COG0840	transmembrane signaling receptor activity
CEP66_RS11465	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CEP66_RS11470	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS11475	COG5557	Pfam Polysulphide reductase, NrfD
CEP66_RS11480	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CEP66_RS11485	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CEP66_RS11490	COG1773	rubredoxin
CEP66_RS11500	COG0298	carbon dioxide binding
CEP66_RS11505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP66_RS11515	COG0625	glutathione transferase activity
CEP66_RS11520	COG0243	molybdopterin cofactor binding
CEP66_RS11525	COG0754	glutathionylspermidine amidase activity
CEP66_RS11530	COG1064	alcohol dehydrogenase
CEP66_RS11535	COG2207	Transcriptional regulator
CEP66_RS11575	COG2205	protein histidine kinase activity
CEP66_RS11575	COG2198	Histidine kinase
CEP66_RS11575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS11575	COG0784	Response regulator, receiver
CEP66_RS11580	COG2197	response regulator
CEP66_RS11605	COG3501	Rhs element vgr protein
CEP66_RS11690	COG3157	Type VI secretion system effector, Hcp
CEP66_RS11735	COG1811	Na channel or pump
CEP66_RS11745	COG1982	Orn Lys Arg decarboxylase major
CEP66_RS11750	COG2211	Major facilitator Superfamily
CEP66_RS11765	COG1194	a g-specific adenine glycosylase
CEP66_RS11775	COG3171	Protein conserved in bacteria
CEP66_RS11785	COG0252	asparaginase activity
CEP66_RS11790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CEP66_RS11805	COG0762	integral membrane protein
CEP66_RS11810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CEP66_RS11815	COG2805	Type II/IV secretion system protein
CEP66_RS11830	COG0189	ligase activity
CEP66_RS11835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CEP66_RS11840	COG2356	endonuclease I
CEP66_RS11850	COG2814	Major facilitator Superfamily
CEP66_RS11870	COG1166	arginine decarboxylase activity
CEP66_RS11885	COG0501	Belongs to the peptidase M48B family
CEP66_RS11890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEP66_RS11895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS11900	COG2213	PTS system mannitol-specific
CEP66_RS11905	COG1063	alcohol dehydrogenase
CEP66_RS11910	COG1494	fructose-1,6-bisphosphatase
CEP66_RS11920	COG1072	(Pantothenic acid kinase))
CEP66_RS11925	COG1122	ATPase activity
CEP66_RS11930	COG1122	ATPase activity
CEP66_RS11960	COG0191	fructose-bisphosphate aldolase activity
CEP66_RS11965	COG0549	Belongs to the carbamate kinase family
CEP66_RS11970	COG2271	Major facilitator Superfamily
CEP66_RS11975	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP66_RS11980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CEP66_RS11990	COG0583	DNA-binding transcription factor activity
CEP66_RS11995	COG0668	transmembrane transport
CEP66_RS12010	COG2968	Membrane
CEP66_RS12030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CEP66_RS12035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CEP66_RS12060	COG0006	proline dipeptidase activity
CEP66_RS12065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEP66_RS12070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEP66_RS12090	COG2723	6-phospho-beta-galactosidase activity
CEP66_RS12095	COG1737	Transcriptional regulator
CEP66_RS12105	COG1272	protein, Hemolysin III
CEP66_RS12120	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CEP66_RS12130	COG0716	FMN binding
CEP66_RS12145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CEP66_RS12170	COG4942	peptidase
CEP66_RS12180	COG1556	Lactate utilization protein
CEP66_RS12185	COG1139	Iron-sulfur cluster binding protein
CEP66_RS12190	COG0247	lactate metabolic process
CEP66_RS12195	COG1620	l-lactate permease
CEP66_RS12200	COG3592	Divergent 4Fe-4S mono-cluster
CEP66_RS12205	COG2388	GCN5-related N-acetyl-transferase
CEP66_RS12225	COG3121	Chaperone
CEP66_RS12250	COG2771	luxR family
CEP66_RS12265	COG0814	amino acid
CEP66_RS12280	COG0183	Belongs to the thiolase family
CEP66_RS12290	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS12300	COG1794	racemase activity, acting on amino acids and derivatives
CEP66_RS12305	COG0583	DNA-binding transcription factor activity
CEP66_RS12315	COG1609	Transcriptional regulator
CEP66_RS12340	COG0667	Aldo Keto reductase
CEP66_RS12350	COG0861	Integral membrane protein TerC family
CEP66_RS12385	COG2165	general secretion pathway protein
CEP66_RS12390	COG4795	General secretion pathway protein
CEP66_RS12400	COG4967	type IV pilus modification protein PilV
CEP66_RS12405	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CEP66_RS12415	COG1074	ATP-dependent DNA helicase activity
CEP66_RS12420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CEP66_RS12425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CEP66_RS12425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CEP66_RS12430	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP66_RS12450	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CEP66_RS12455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CEP66_RS12460	COG2166	iron-sulfur cluster assembly
CEP66_RS12465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CEP66_RS12475	COG0583	DNA-binding transcription factor activity
CEP66_RS12480	COG2363	Small membrane protein
CEP66_RS12490	COG1349	DNA-binding transcription factor activity
CEP66_RS12510	COG0738	Major facilitator superfamily
CEP66_RS12520	COG0235	Class ii aldolase
CEP66_RS12525	COG1454	alcohol dehydrogenase
CEP66_RS12540	COG1760	l-serine dehydratase
CEP66_RS12545	COG0814	amino acid
CEP66_RS12555	COG1611	Belongs to the LOG family
CEP66_RS12570	COG3098	single-species biofilm formation
CEP66_RS12575	COG0564	pseudouridine synthase activity
CEP66_RS12580	COG0716	FMN binding
CEP66_RS12590	COG2271	Major facilitator Superfamily
CEP66_RS12595	COG4948	Mandelate Racemase Muconate Lactonizing
CEP66_RS12600	COG4948	Mandelate Racemase Muconate Lactonizing
CEP66_RS12605	COG1929	Belongs to the glycerate kinase type-1 family
CEP66_RS12610	COG2205	protein histidine kinase activity
CEP66_RS12610	COG3437	response regulator, receiver
CEP66_RS12610	COG3850	Histidine kinase
CEP66_RS12610	COG4999	Histidine kinase
CEP66_RS12620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CEP66_RS12625	COG3956	TIGRFAM MazG family protein
CEP66_RS12645	COG0602	queuosine metabolic process
CEP66_RS12650	COG1070	Carbohydrate kinase
CEP66_RS12655	COG2223	nitrite transmembrane transporter activity
CEP66_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS12665	COG0277	FAD linked oxidase domain protein
CEP66_RS12670	COG0477	Major facilitator Superfamily
CEP66_RS12675	COG2086	electron transfer activity
CEP66_RS12680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CEP66_RS12685	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CEP66_RS12690	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CEP66_RS12695	COG0644	oxidoreductase
CEP66_RS12700	COG0720	synthase
CEP66_RS12730	COG2234	aminopeptidase activity
CEP66_RS12785	COG1388	LysM domain
CEP66_RS12785	COG4942	peptidase
CEP66_RS12800	COG0163	prenyltransferase activity
CEP66_RS12805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CEP66_RS12825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP66_RS12830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP66_RS12835	COG1121	(ABC) transporter
CEP66_RS12860	COG0309	Hydrogenase expression formation protein (HypE)
CEP66_RS12865	COG0409	Hydrogenase expression formation protein
CEP66_RS12870	COG0298	carbon dioxide binding
CEP66_RS12875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CEP66_RS12880	COG0375	protein maturation
CEP66_RS12890	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS12895	COG0651	ATP synthesis coupled electron transport
CEP66_RS12900	COG0650	Formate hydrogenlyase subunit 4
CEP66_RS12905	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CEP66_RS12905	COG3261	NADH dehydrogenase
CEP66_RS12910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEP66_RS12915	COG3260	NADH ubiquinone oxidoreductase 20
CEP66_RS12925	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CEP66_RS12930	COG2723	6-phospho-beta-galactosidase activity
CEP66_RS12935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS12935	COG1263	PTS System
CEP66_RS12940	COG1609	Transcriptional regulator
CEP66_RS12945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS12950	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CEP66_RS12970	COG0517	IMP dehydrogenase activity
CEP66_RS12970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CEP66_RS12975	COG1349	DNA-binding transcription factor activity
CEP66_RS12980	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS12995	COG3732	PTS system glucitol sorbitol-specific
CEP66_RS13000	COG3730	PTS system glucitol sorbitol-specific
CEP66_RS13005	COG2951	lytic endotransglycosylase activity
CEP66_RS13020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP66_RS13030	COG1546	Belongs to the CinA family
CEP66_RS13050	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CEP66_RS13080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP66_RS13085	COG1238	metal cluster binding
CEP66_RS13100	COG2814	Major facilitator Superfamily
CEP66_RS13105	COG1566	PFAM secretion protein HlyD family protein
CEP66_RS13110	COG1846	Transcriptional regulator
CEP66_RS13120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CEP66_RS13125	COG2814	Major facilitator Superfamily
CEP66_RS13135	COG4176	ABC-type proline glycine betaine transport system permease component
CEP66_RS13170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEP66_RS13180	COG4575	ribosome binding
CEP66_RS13205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CEP66_RS13210	COG1652	LysM domain
CEP66_RS13215	COG1802	Transcriptional regulator
CEP66_RS13220	COG1113	amino acid transport
CEP66_RS13225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CEP66_RS13230	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS13235	COG0579	oxidoreductase
CEP66_RS13300	COG3962	Belongs to the TPP enzyme family
CEP66_RS13305	COG0673	inositol 2-dehydrogenase activity
CEP66_RS13320	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS13325	COG0673	inositol 2-dehydrogenase activity
CEP66_RS13330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS13340	COG3718	enzyme involved in inositol metabolism
CEP66_RS13345	COG0840	transmembrane signaling receptor activity
CEP66_RS13355	COG1129	ABC transporter
CEP66_RS13360	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS13400	COG3477	response to acidic pH
CEP66_RS13425	COG2867	negative regulation of translational initiation
CEP66_RS13435	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEP66_RS13440	COG0497	DNA recombination
CEP66_RS13460	COG4536	flavin adenine dinucleotide binding
CEP66_RS13465	COG4137	Cytochrome C assembly protein
CEP66_RS13470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CEP66_RS13505	COG2885	chlorophyll binding
CEP66_RS13510	COG2199	diguanylate cyclase activity
CEP66_RS13530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEP66_RS13535	COG1605	Chorismate mutase
CEP66_RS13535	COG0287	Prephenate dehydrogenase
CEP66_RS13540	COG1605	Chorismate mutase
CEP66_RS13540	COG0077	Prephenate dehydratase
CEP66_RS13550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CEP66_RS13555	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEP66_RS13560	COG0564	pseudouridine synthase activity
CEP66_RS13570	COG0542	response to heat
CEP66_RS13595	COG0477	Major facilitator Superfamily
CEP66_RS13600	COG5544	Lipoprotein
CEP66_RS13605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEP66_RS13615	COG3148	PFAM DTW domain containing protein
CEP66_RS13620	COG3118	belongs to the thioredoxin family
CEP66_RS13625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CEP66_RS13640	COG0513	Belongs to the DEAD box helicase family
CEP66_RS13650	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CEP66_RS13665	COG3026	antisigma factor binding
CEP66_RS13670	COG3086	response to oxidative stress
CEP66_RS13680	COG0681	Belongs to the peptidase S26 family
CEP66_RS13705	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CEP66_RS13715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS13980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CEP66_RS13980	COG2755	lipolytic protein G-D-S-L family
CEP66_RS13995	COG1737	Transcriptional regulator
CEP66_RS14005	COG0560	Phosphoserine phosphatase
CEP66_RS14035	COG2205	protein histidine kinase activity
CEP66_RS14040	COG3170	Tfp pilus assembly protein FimV
CEP66_RS14045	COG2204	response regulator
CEP66_RS14050	COG0347	Belongs to the P(II) protein family
CEP66_RS14070	COG1940	carbohydrate kinase activity
CEP66_RS14075	COG0457	Tetratricopeptide repeat
CEP66_RS14080	COG0477	Major facilitator Superfamily
CEP66_RS14080	COG2814	Major facilitator Superfamily
CEP66_RS14085	COG2017	converts alpha-aldose to the beta-anomer
CEP66_RS14090	COG2814	Major facilitator Superfamily
CEP66_RS14095	COG3711	transcriptional antiterminator
CEP66_RS14100	COG3683	transport system, periplasmic component
CEP66_RS14105	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CEP66_RS14130	COG0822	iron-sulfur transferase activity
CEP66_RS14150	COG0633	Ferredoxin
CEP66_RS14155	COG2975	iron-sulfur cluster assembly
CEP66_RS14170	COG2897	thiosulfate sulfurtransferase activity
CEP66_RS14175	COG2373	Large extracellular alpha-helical protein
CEP66_RS14180	COG4953	penicillin-binding protein 1C
CEP66_RS14215	COG2976	Protein conserved in bacteria
CEP66_RS14235	COG1645	bacterial-type flagellum-dependent swarming motility
CEP66_RS14245	COG0517	IMP dehydrogenase activity
CEP66_RS14245	COG0516	GMP reductase activity
CEP66_RS14260	COG2200	EAL domain
CEP66_RS14275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CEP66_RS14290	COG2723	6-phospho-beta-galactosidase activity
CEP66_RS14300	COG2233	PERMEase
CEP66_RS14310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CEP66_RS14315	COG1446	asparaginase
CEP66_RS14320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP66_RS14330	COG1393	Belongs to the ArsC family
CEP66_RS14335	COG4783	chaperone-mediated protein folding
CEP66_RS14345	COG0628	permease
CEP66_RS14350	COG3366	ferrous iron transmembrane transporter activity
CEP66_RS14355	COG0700	Nucleoside recognition
CEP66_RS14360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CEP66_RS14365	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CEP66_RS14370	COG2716	regulation of RNA biosynthetic process
CEP66_RS14380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CEP66_RS14390	COG2321	neutral zinc metallopeptidase
CEP66_RS14400	COG0400	carboxylic ester hydrolase activity
CEP66_RS14415	COG1393	Belongs to the ArsC family
CEP66_RS14425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CEP66_RS14430	COG3850	Histidine kinase
CEP66_RS14435	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS14435	COG0493	'glutamate synthase
CEP66_RS14450	COG5342	invasion associated locus B
CEP66_RS14455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CEP66_RS14555	COG2207	Transcriptional regulator
CEP66_RS14565	COG0860	N-Acetylmuramoyl-L-alanine amidase
CEP66_RS14585	COG2837	iron assimilation
CEP66_RS14590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CEP66_RS14595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS14595	COG1263	PTS System
CEP66_RS14605	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CEP66_RS14625	COG4150	thiosulfate binding
CEP66_RS14630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CEP66_RS14635	COG4208	sulfate ABC transporter
CEP66_RS14640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CEP66_RS14680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS14705	COG3530	Putative quorum-sensing-regulated virulence factor
CEP66_RS14710	COG0385	Bile acid
CEP66_RS14715	COG0583	DNA-binding transcription factor activity
CEP66_RS14725	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CEP66_RS14730	COG2211	Major facilitator Superfamily
CEP66_RS14735	COG0583	DNA-binding transcription factor activity
CEP66_RS14770	COG3415	Transposase
CEP66_RS14775	COG3415	Transposase
CEP66_RS14790	COG2199	diguanylate cyclase activity
CEP66_RS14790	COG2200	EAL domain
CEP66_RS14795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEP66_RS14810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEP66_RS14815	COG1263	PTS System
CEP66_RS14815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS14825	COG0667	Aldo Keto reductase
CEP66_RS14830	COG3961	Belongs to the TPP enzyme family
CEP66_RS14845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS14850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS14855	COG0006	proline dipeptidase activity
CEP66_RS14860	COG1363	Peptidase, m42
CEP66_RS14865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS14865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS14865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEP66_RS14870	COG2207	Transcriptional regulator
CEP66_RS14875	COG3279	Response regulator of the LytR AlgR family
CEP66_RS14880	COG3275	phosphorelay sensor kinase activity
CEP66_RS14885	COG0436	Aminotransferase
CEP66_RS14895	COG1560	Kdo2-lipid A biosynthetic process
CEP66_RS14920	COG5001	Diguanylate cyclase
CEP66_RS14920	COG1716	ATPase activity
CEP66_RS14930	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CEP66_RS14945	COG0583	DNA-binding transcription factor activity
CEP66_RS14955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEP66_RS14960	COG2199	diguanylate cyclase activity
CEP66_RS14960	COG2200	EAL domain
CEP66_RS14960	COG2202	Pas domain
CEP66_RS14975	COG2814	Major facilitator Superfamily
CEP66_RS14985	COG2116	formate transmembrane transporter activity
CEP66_RS14995	COG2067	long-chain fatty acid transport protein
CEP66_RS15005	COG3691	Protein conserved in bacteria
CEP66_RS15020	COG2062	phosphohistidine phosphatase, SixA
CEP66_RS15045	COG0730	response to heat
CEP66_RS15050	COG3101	peptidyl-lysine hydroxylation
CEP66_RS15065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEP66_RS15105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CEP66_RS15115	COG0586	Pfam SNARE associated Golgi protein
CEP66_RS15125	COG0285	dihydrofolate synthase activity
CEP66_RS15130	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CEP66_RS15135	COG1286	toxin biosynthetic process
CEP66_RS15140	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CEP66_RS15160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS15170	COG4160	amino acid transport
CEP66_RS15175	COG4598	ABC transporter
CEP66_RS15180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP66_RS15185	COG1090	epimerase
CEP66_RS15190	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CEP66_RS15195	COG0625	glutathione transferase activity
CEP66_RS15200	COG0622	Phosphoesterase
CEP66_RS15210	COG1609	Transcriptional regulator
CEP66_RS15215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS15225	COG3037	sugar-specific permease SgaT UlaA
CEP66_RS15230	COG3959	Transketolase, thiamine diphosphate binding domain
CEP66_RS15235	COG3958	Transketolase
CEP66_RS15245	COG1288	antiporter activity
CEP66_RS15270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP66_RS15275	COG0490	domain, Protein
CEP66_RS15275	COG0471	metal ion transport
CEP66_RS15285	COG0436	Aminotransferase
CEP66_RS15290	COG0583	DNA-binding transcription factor activity
CEP66_RS15335	COG0839	Belongs to the complex I subunit 6 family
CEP66_RS15345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CEP66_RS15350	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEP66_RS15360	COG0835	chemotaxis
CEP66_RS15360	COG0784	Response regulator, receiver
CEP66_RS15370	COG2153	protein acetylation
CEP66_RS15375	COG4575	ribosome binding
CEP66_RS15380	COG1169	isochorismate synthase
CEP66_RS15425	COG0247	lactate metabolic process
CEP66_RS15435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CEP66_RS15440	COG2271	Major facilitator Superfamily
CEP66_RS15445	COG0584	glycerophosphoryl diester phosphodiesterase
CEP66_RS15450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEP66_RS15460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CEP66_RS15480	COG0183	Belongs to the thiolase family
CEP66_RS15485	COG2031	fatty acid transporter
CEP66_RS15490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CEP66_RS15495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CEP66_RS15500	COG2204	response regulator
CEP66_RS15505	COG3852	Histidine kinase
CEP66_RS15515	COG2197	response regulator
CEP66_RS15520	COG0642	Histidine kinase
CEP66_RS15520	COG2198	Histidine kinase
CEP66_RS15545	COG2169	Transcriptional regulator
CEP66_RS15545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEP66_RS15550	COG3145	DNA-N1-methyladenine dioxygenase activity
CEP66_RS15555	COG4615	Cyclic peptide transporter
CEP66_RS15560	COG2239	Acts as a magnesium transporter
CEP66_RS15575	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS15575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CEP66_RS15580	COG3062	negative regulation of establishment of protein localization
CEP66_RS15590	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS15595	COG0348	domain, Protein
CEP66_RS15600	COG3043	anaerobic respiration
CEP66_RS15605	COG3005	denitrification pathway
CEP66_RS15610	COG4133	protoheme IX ABC transporter activity
CEP66_RS15620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEP66_RS15625	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CEP66_RS15635	COG1138	Cytochrome C-type biogenesis protein
CEP66_RS15640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP66_RS15645	COG4235	cytochrome complex assembly
CEP66_RS15645	COG3088	subunit of a heme lyase
CEP66_RS15650	COG2197	response regulator
CEP66_RS15710	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CEP66_RS15715	COG5532	Uncharacterized conserved protein (DUF2303)
CEP66_RS15730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CEP66_RS15770	COG3645	SOS response
CEP66_RS15770	COG3646	Phage regulatory protein
CEP66_RS15775	COG1403	HNH endonuclease
CEP66_RS15780	COG0484	heat shock protein binding
CEP66_RS15800	COG3179	chitinase
CEP66_RS15835	COG4220	transposase activity
CEP66_RS15855	COG1030	water channel activity
CEP66_RS15905	COG1196	nuclear chromosome segregation
CEP66_RS16010	COG1061	Type III restriction enzyme res subunit
CEP66_RS16015	COG1187	pseudouridine synthase activity
CEP66_RS16020	COG2814	Major facilitator Superfamily
CEP66_RS16030	COG4172	Belongs to the ABC transporter superfamily
CEP66_RS16035	COG4239	(ABC) transporter, permease
CEP66_RS16040	COG4174	ABC transporter (Permease)
CEP66_RS16045	COG4166	transmembrane transport
CEP66_RS16050	COG2200	EAL domain
CEP66_RS16055	COG0791	NLP P60 protein
CEP66_RS16065	COG0671	phosphoesterase, PA-phosphatase related
CEP66_RS16070	COG0523	cobalamin synthesis protein
CEP66_RS16075	COG0246	Mannitol dehydrogenase
CEP66_RS16105	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP66_RS16110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CEP66_RS16110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS16110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CEP66_RS16115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS16120	COG2313	pseudouridylate synthase activity
CEP66_RS16125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CEP66_RS16130	COG1522	sequence-specific DNA binding
CEP66_RS16130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS16140	COG2855	membrane
CEP66_RS16145	COG0583	DNA-binding transcription factor activity
CEP66_RS16150	COG0833	amino acid
CEP66_RS16155	COG4771	TonB-dependent receptor
CEP66_RS16160	COG2271	Major facilitator Superfamily
CEP66_RS16165	COG0560	Phosphoserine phosphatase
CEP66_RS16170	COG1760	l-serine dehydratase
CEP66_RS16190	COG2311	Membrane
CEP66_RS16210	COG1129	ABC transporter
CEP66_RS16225	COG2949	membrane
CEP66_RS16235	COG1346	cytolysis
CEP66_RS16250	COG2271	Major facilitator Superfamily
CEP66_RS16265	COG0625	glutathione transferase activity
CEP66_RS16270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CEP66_RS16275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CEP66_RS16280	COG1538	Outer membrane efflux protein
CEP66_RS16285	COG0586	Pfam SNARE associated Golgi protein
CEP66_RS16295	COG1686	Belongs to the peptidase S11 family
CEP66_RS16300	COG0277	FAD linked oxidase domain protein
CEP66_RS16310	COG1472	Belongs to the glycosyl hydrolase 3 family
CEP66_RS16315	COG1732	Glycine betaine
CEP66_RS16320	COG1174	glycine betaine transport
CEP66_RS16325	COG1125	glycine betaine transport
CEP66_RS16330	COG1174	glycine betaine transport
CEP66_RS16340	COG0789	Transcriptional regulator
CEP66_RS16345	COG3275	phosphorelay sensor kinase activity
CEP66_RS16355	COG4807	Protein conserved in bacteria
CEP66_RS16380	COG3121	Chaperone
CEP66_RS16385	COG3188	usher protein
CEP66_RS16395	COG5455	response to cobalt ion
CEP66_RS16405	COG0351	phosphomethylpyrimidine kinase
CEP66_RS16410	COG2188	Transcriptional regulator
CEP66_RS16415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CEP66_RS16420	COG1397	ADP-ribosylglycohydrolase
CEP66_RS16425	COG2211	Major facilitator Superfamily
CEP66_RS16430	COG1830	Aldolase
CEP66_RS16435	COG1070	Carbohydrate kinase
CEP66_RS16460	COG1070	Carbohydrate kinase
CEP66_RS16470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP66_RS16505	COG0826	peptidase U32
CEP66_RS16510	COG0745	RESPONSE REGULATOR receiver
CEP66_RS16515	COG2205	protein histidine kinase activity
CEP66_RS16540	COG0443	Heat shock 70 kDa protein
CEP66_RS16550	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CEP66_RS16555	COG5002	protein histidine kinase activity
CEP66_RS16555	COG3447	MASE1 domain protein
CEP66_RS16555	COG5001	Diguanylate cyclase
CEP66_RS16570	COG2982	Protein involved in outer membrane biogenesis
CEP66_RS16575	COG1253	flavin adenine dinucleotide binding
CEP66_RS16595	COG0489	protein tyrosine kinase activity
CEP66_RS16595	COG3206	protein involved in exopolysaccharide biosynthesis
CEP66_RS16600	COG0463	Glycosyl transferase, family 2
CEP66_RS16605	COG1045	serine acetyltransferase
CEP66_RS16610	COG0438	transferase activity, transferring glycosyl groups
CEP66_RS16620	COG1216	Glycosyl transferase, family 2
CEP66_RS16625	COG0110	maltose O-acetyltransferase activity
CEP66_RS16630	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CEP66_RS16635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP66_RS16640	COG1051	belongs to the nudix hydrolase family
CEP66_RS16645	COG0297	glycogen (starch) synthase activity
CEP66_RS16655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CEP66_RS16660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CEP66_RS16665	COG2244	polysaccharide biosynthetic process
CEP66_RS16670	COG2327	Polysaccharide pyruvyl transferase
CEP66_RS16690	COG1086	Polysaccharide biosynthesis protein
CEP66_RS16695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CEP66_RS16700	COG1083	cytidylyl-transferase
CEP66_RS16710	COG2089	acid synthase
CEP66_RS16730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CEP66_RS16730	COG1215	transferase activity, transferring glycosyl groups
CEP66_RS16760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CEP66_RS16785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CEP66_RS16815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP66_RS16820	COG0583	DNA-binding transcription factor activity
CEP66_RS16830	COG0531	amino acid
CEP66_RS16835	COG2925	Exonuclease
CEP66_RS16850	COG1289	transmembrane transporter activity
CEP66_RS16885	COG4656	Part of a membrane complex involved in electron transport
CEP66_RS16890	COG1454	alcohol dehydrogenase
CEP66_RS16890	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS16905	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CEP66_RS17080	COG0583	DNA-binding transcription factor activity
CEP66_RS17120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS17125	COG4106	trans-aconitate 2-methyltransferase activity
CEP66_RS17155	COG0534	Mate efflux family protein
CEP66_RS17165	COG3122	Protein conserved in bacteria
CEP66_RS17180	COG1733	regulation of RNA biosynthetic process
CEP66_RS17195	COG0583	DNA-binding transcription factor activity
CEP66_RS17210	COG2267	carboxylic ester hydrolase activity
CEP66_RS17220	COG0243	molybdopterin cofactor binding
CEP66_RS17220	COG3383	formate dehydrogenase (NAD+) activity
CEP66_RS17225	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS17230	COG2864	formate dehydrogenase
CEP66_RS17245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CEP66_RS17250	COG0477	Major facilitator Superfamily
CEP66_RS17255	COG1120	ATPase activity
CEP66_RS17265	COG4139	cobalamin transport
CEP66_RS17290	COG2197	response regulator
CEP66_RS17315	COG1250	3-hydroxyacyl-CoA dehydrogenase
CEP66_RS17320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CEP66_RS17325	COG1960	acyl-CoA dehydrogenase activity
CEP66_RS17355	COG0154	amidase activity
CEP66_RS17380	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CEP66_RS17445	COG3504	Conjugal transfer protein
CEP66_RS17470	COG3451	type IV secretory pathway VirB4
CEP66_RS17510	COG3958	Transketolase
CEP66_RS17515	COG3959	Transketolase, thiamine diphosphate binding domain
CEP66_RS17550	COG0582	viral genome integration into host DNA
CEP66_RS17565	COG0583	DNA-binding transcription factor activity
CEP66_RS17600	COG3423	Transcriptional regulator
CEP66_RS17615	COG0582	viral genome integration into host DNA
CEP66_RS17715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEP66_RS17720	COG1418	mRNA catabolic process
CEP66_RS17725	COG0270	DNA (cytosine-5-)-methyltransferase activity
CEP66_RS17730	COG3727	T/G mismatch-specific endonuclease activity
CEP66_RS17735	COG0697	spore germination
CEP66_RS17740	COG2354	Protein conserved in bacteria
CEP66_RS17745	COG5475	Uncharacterized small protein (DUF2158)
CEP66_RS17765	COG2197	response regulator
CEP66_RS17780	COG1338	Plays a role in the flagellum-specific transport system
CEP66_RS17800	COG1580	Controls the rotational direction of flagella during chemotaxis
CEP66_RS17840	COG0425	Belongs to the sulfur carrier protein TusA family
CEP66_RS17855	COG0366	Alpha amylase catalytic
CEP66_RS17875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CEP66_RS17880	COG0500	methyltransferase
CEP66_RS17920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS17930	COG0765	amino acid transport
CEP66_RS17935	COG1126	abc transporter atp-binding protein
CEP66_RS17940	COG2197	response regulator
CEP66_RS17950	COG2197	response regulator
CEP66_RS17980	COG3318	Belongs to the UPF0149 family
CEP66_RS17980	COG3012	SEC-C Motif Domain Protein
CEP66_RS17985	COG0814	amino acid
CEP66_RS17995	COG1528	Iron-storage protein
CEP66_RS18015	COG1528	Iron-storage protein
CEP66_RS18030	COG1879	ABC-type sugar transport system periplasmic component
CEP66_RS18035	COG1129	ABC transporter
CEP66_RS18040	COG1172	Belongs to the binding-protein-dependent transport system permease family
CEP66_RS18095	COG1301	dicarboxylic acid transport
CEP66_RS18105	COG0840	transmembrane signaling receptor activity
CEP66_RS18120	COG0745	RESPONSE REGULATOR receiver
CEP66_RS18130	COG3539	Fimbrial protein
CEP66_RS18135	COG3188	usher protein
CEP66_RS18140	COG3121	Chaperone
CEP66_RS18145	COG3539	Fimbrial protein
CEP66_RS18175	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CEP66_RS18190	COG3102	Protein conserved in bacteria
CEP66_RS18210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
CEP66_RS18215	COG1801	Protein of unknown function DUF72
CEP66_RS18220	COG1335	isochorismatase
CEP66_RS18230	COG0494	nUDIX hydrolase
CEP66_RS18255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CEP66_RS18265	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CEP66_RS18270	COG0739	heme binding
CEP66_RS18275	COG1560	Kdo2-lipid A biosynthetic process
CEP66_RS18285	COG1737	Transcriptional regulator
CEP66_RS18290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CEP66_RS18295	COG0129	dihydroxy-acid dehydratase activity
CEP66_RS18300	COG0800	Aldolase
CEP66_RS18310	COG3141	response to X-ray
CEP66_RS18320	COG2979	Protein of unknown function (DUF533)
CEP66_RS18325	COG1770	oligopeptidase
CEP66_RS18330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEP66_RS18335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CEP66_RS18345	COG2372	response to copper ion
CEP66_RS18350	COG1276	copper resistance
CEP66_RS18400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CEP66_RS18460	COG1846	Transcriptional regulator
CEP66_RS18560	COG0484	heat shock protein binding
CEP66_RS18575	COG3772	lysozyme
CEP66_RS18590	COG5484	DNA packaging
CEP66_RS18590	COG3728	DNA packaging
CEP66_RS18690	COG1196	nuclear chromosome segregation
CEP66_RS18725	COG0463	Glycosyl transferase, family 2
CEP66_RS18755	COG4771	TonB-dependent receptor
CEP66_RS18760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CEP66_RS18780	COG3008	intermembrane lipid transfer
CEP66_RS18785	COG2995	paraquat-inducible protein a
CEP66_RS18790	COG1956	GAF domain-containing protein
CEP66_RS18810	COG2814	Major facilitator Superfamily
CEP66_RS18815	COG1414	Transcriptional regulator
CEP66_RS18845	COG0768	penicillin binding
CEP66_RS18850	COG2226	methyltransferase
CEP66_RS18865	COG3716	PTS system mannose fructose sorbose family IID component
CEP66_RS18870	COG3715	PTS system
CEP66_RS18875	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS18875	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS18890	COG1253	flavin adenine dinucleotide binding
CEP66_RS18895	COG2200	EAL domain
CEP66_RS18900	COG1760	l-serine dehydratase
CEP66_RS18920	COG0251	oxidation-reduction process
CEP66_RS18925	COG1199	ATP-dependent helicase activity
CEP66_RS18930	COG1214	PFAM Peptidase M22, glycoprotease
CEP66_RS18935	COG3065	identical protein binding
CEP66_RS18940	COG0318	PFAM AMP-dependent synthetase and ligase
CEP66_RS18945	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CEP66_RS18950	COG0473	3-isopropylmalate dehydrogenase activity
CEP66_RS18955	COG0583	DNA-binding transcription factor activity
CEP66_RS18960	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CEP66_RS18965	COG2894	cell division
CEP66_RS18980	COG0179	Fumarylacetoacetate (FAA) hydrolase
CEP66_RS19015	COG2719	SpoVR family
CEP66_RS19025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CEP66_RS19035	COG1619	proteins homologs of microcin C7 resistance protein MccF
CEP66_RS19045	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CEP66_RS19055	COG4774	siderophore transport
CEP66_RS19065	COG0157	Belongs to the NadC ModD family
CEP66_RS19075	COG1120	ATPase activity
CEP66_RS19080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS19085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CEP66_RS19100	COG1461	Dihydroxyacetone kinase
CEP66_RS19105	COG2376	Dihydroxyacetone kinase
CEP66_RS19110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CEP66_RS19125	COG3121	Chaperone
CEP66_RS19150	COG0583	DNA-binding transcription factor activity
CEP66_RS19155	COG0243	molybdopterin cofactor binding
CEP66_RS19160	COG1271	oxidase subunit
CEP66_RS19165	COG1294	oxidase, subunit
CEP66_RS19180	COG3781	membrane
CEP66_RS19205	COG0454	-acetyltransferase
CEP66_RS19210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP66_RS19225	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CEP66_RS19230	COG0456	acetyltransferase
CEP66_RS19235	COG4771	TonB-dependent receptor
CEP66_RS19240	COG1021	2,3-dihydroxybenzoate-AMP ligase
CEP66_RS19260	COG3433	isochorismatase activity
CEP66_RS19260	COG2226	methyltransferase
CEP66_RS19260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CEP66_RS19275	COG1132	(ABC) transporter
CEP66_RS19280	COG2814	Major facilitator Superfamily
CEP66_RS19285	COG1169	isochorismate synthase
CEP66_RS19295	COG0012	GTP binding
CEP66_RS19335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS19350	COG0659	secondary active sulfate transmembrane transporter activity
CEP66_RS19380	COG2890	protein-(glutamine-N5) methyltransferase activity
CEP66_RS19400	COG0387	Pfam Sodium calcium exchanger
CEP66_RS19405	COG4572	Cation transport regulator
CEP66_RS19410	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CEP66_RS19420	COG0840	transmembrane signaling receptor activity
CEP66_RS19425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CEP66_RS19430	COG3707	response regulator
CEP66_RS19435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEP66_RS19440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEP66_RS19445	COG1116	anion transmembrane transporter activity
CEP66_RS19450	COG2146	nitrite reductase [NAD(P)H] activity
CEP66_RS19450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CEP66_RS19455	COG0243	molybdopterin cofactor binding
CEP66_RS19460	COG4932	domain protein
CEP66_RS19465	COG2197	response regulator
CEP66_RS19475	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CEP66_RS19480	COG2181	nitrate reductase activity
CEP66_RS19500	COG0788	formyltetrahydrofolate deformylase activity
CEP66_RS19510	COG1752	Esterase of the alpha-beta hydrolase superfamily
CEP66_RS19515	COG0745	RESPONSE REGULATOR receiver
CEP66_RS19520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CEP66_RS19530	COG1435	thymidine kinase activity
CEP66_RS19535	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS19535	COG1454	alcohol dehydrogenase
CEP66_RS19540	COG2095	MarC family integral membrane protein
CEP66_RS19565	COG0444	Belongs to the ABC transporter superfamily
CEP66_RS19570	COG4608	Belongs to the ABC transporter superfamily
CEP66_RS19585	COG2350	Protein conserved in bacteria
CEP66_RS19610	COG3047	cAMP biosynthetic process
CEP66_RS19620	COG3706	GGDEF domain
CEP66_RS19660	COG0009	L-threonylcarbamoyladenylate synthase
CEP66_RS19665	COG1187	pseudouridine synthase activity
CEP66_RS19675	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS19680	COG0616	signal peptide processing
CEP66_RS19715	COG0671	phosphoesterase, PA-phosphatase related
CEP66_RS19720	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CEP66_RS19725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CEP66_RS19735	COG0023	Translation Initiation Factor
CEP66_RS19745	COG1349	DNA-binding transcription factor activity
CEP66_RS19760	COG5001	Diguanylate cyclase
CEP66_RS19770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEP66_RS19770	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEP66_RS19775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CEP66_RS19790	COG3204	pilus organization
CEP66_RS19830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CEP66_RS19835	COG1842	Phage shock protein A
CEP66_RS19845	COG1983	PspC domain protein
CEP66_RS19855	COG3106	COG3106 Predicted ATPase
CEP66_RS19870	COG2211	Major facilitator Superfamily
CEP66_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
CEP66_RS19900	COG2866	Carboxypeptidase
CEP66_RS19905	COG4166	transmembrane transport
CEP66_RS19910	COG0668	transmembrane transport
CEP66_RS19915	COG3182	Iron-regulated membrane protein
CEP66_RS19935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CEP66_RS19940	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CEP66_RS19945	COG2840	Smr protein MutS2
CEP66_RS19950	COG3706	GGDEF domain
CEP66_RS19965	COG0513	Belongs to the DEAD box helicase family
CEP66_RS19985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CEP66_RS19990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CEP66_RS19990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CEP66_RS19990	COG1013	pyruvate-flavodoxin oxidoreductase activity
CEP66_RS19990	COG0674	pyruvate-flavodoxin oxidoreductase activity
CEP66_RS19995	COG3042	response to heat
CEP66_RS20000	COG3187	Heat shock protein
CEP66_RS20005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CEP66_RS20025	COG2911	Protein conserved in bacteria
CEP66_RS20035	COG3784	Protein of unknown function (DUF1318)
CEP66_RS20040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEP66_RS20045	COG4589	Belongs to the CDS family
CEP66_RS20055	COG2267	carboxylic ester hydrolase activity
CEP66_RS20060	COG2453	phosphatase
CEP66_RS20060	COG0671	phosphoesterase, PA-phosphatase related
CEP66_RS20070	COG0667	Aldo Keto reductase
CEP66_RS20080	COG1643	Atp-dependent helicase
CEP66_RS20085	COG0583	DNA-binding transcription factor activity
CEP66_RS20095	COG1538	Outer membrane efflux protein
CEP66_RS20110	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEP66_RS20115	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS20120	COG2755	lipolytic protein G-D-S-L family
CEP66_RS20120	COG0657	acetylesterase activity
CEP66_RS20125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CEP66_RS20130	COG3038	cytochrome b561
CEP66_RS20160	COG0840	transmembrane signaling receptor activity
CEP66_RS20165	COG0583	DNA-binding transcription factor activity
CEP66_RS20170	COG1227	inorganic diphosphatase activity
CEP66_RS20175	COG5383	Protein conserved in bacteria
CEP66_RS20180	COG2272	Belongs to the type-B carboxylesterase lipase family
CEP66_RS20195	COG2841	Protein conserved in bacteria
CEP66_RS20200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP66_RS20205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CEP66_RS20210	COG1275	C4-dicarboxylate transporter malic acid transport protein
CEP66_RS20215	COG0500	methyltransferase
CEP66_RS20225	COG0697	spore germination
CEP66_RS20235	COG3135	benzoate transporter
CEP66_RS20240	COG1396	sequence-specific DNA binding
CEP66_RS20245	COG0826	peptidase U32
CEP66_RS20250	COG1724	mRNA binding
CEP66_RS20255	COG1598	PFAM Uncharacterised protein family UPF0150
CEP66_RS20260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CEP66_RS20295	COG0747	negative chemotaxis
CEP66_RS20305	COG3238	Protein conserved in bacteria
CEP66_RS20310	COG1247	-acetyltransferase
CEP66_RS20320	COG2130	NADP-dependent
CEP66_RS20325	COG4772	TonB-dependent receptor
CEP66_RS20340	COG0625	glutathione transferase activity
CEP66_RS20350	COG4251	negative regulation of phosphorylation
CEP66_RS20350	COG3706	GGDEF domain
CEP66_RS20350	COG2203	Gaf domain
CEP66_RS20350	COG5001	Diguanylate cyclase
CEP66_RS20355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CEP66_RS20360	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CEP66_RS20365	COG2181	nitrate reductase activity
CEP66_RS20370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CEP66_RS20375	COG1140	nitrate reductase beta subunit
CEP66_RS20380	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CEP66_RS20390	COG1309	transcriptional regulator
CEP66_RS20420	COG3383	formate dehydrogenase (NAD+) activity
CEP66_RS20420	COG0243	molybdopterin cofactor binding
CEP66_RS20425	COG0243	molybdopterin cofactor binding
CEP66_RS20425	COG3383	formate dehydrogenase (NAD+) activity
CEP66_RS20430	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS20435	COG2864	formate dehydrogenase
CEP66_RS20450	COG1764	response to oxidative stress
CEP66_RS20455	COG4608	Belongs to the ABC transporter superfamily
CEP66_RS20460	COG0444	Belongs to the ABC transporter superfamily
CEP66_RS20465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CEP66_RS20470	COG0601	transmembrane transport
CEP66_RS20475	COG0747	negative chemotaxis
CEP66_RS20480	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CEP66_RS20490	COG0840	transmembrane signaling receptor activity
CEP66_RS20505	COG1649	PFAM Uncharacterised BCR, COG1649
CEP66_RS20510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CEP66_RS20520	COG0148	phosphopyruvate hydratase activity
CEP66_RS20680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP66_RS20720	COG1012	belongs to the aldehyde dehydrogenase family
CEP66_RS20725	COG0583	DNA-binding transcription factor activity
CEP66_RS20730	COG0039	L-malate dehydrogenase activity
CEP66_RS20745	COG1846	Transcriptional regulator
CEP66_RS20760	COG0697	spore germination
CEP66_RS20765	COG2814	Major facilitator Superfamily
CEP66_RS20795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CEP66_RS20815	COG3706	GGDEF domain
CEP66_RS20830	COG4221	oxidoreductase activity
CEP66_RS20835	COG1802	Transcriptional regulator
CEP66_RS20840	COG0246	Mannitol dehydrogenase
CEP66_RS20845	COG0477	Major facilitator Superfamily
CEP66_RS20850	COG1063	alcohol dehydrogenase
CEP66_RS20855	COG4948	Mandelate Racemase Muconate Lactonizing
CEP66_RS20870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP66_RS20890	COG0243	molybdopterin cofactor binding
CEP66_RS20895	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS20900	COG3302	dmso reductase anchor subunit
CEP66_RS20905	COG3381	protein complex oligomerization
CEP66_RS20935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEP66_RS20940	COG1940	carbohydrate kinase activity
CEP66_RS20945	COG0583	DNA-binding transcription factor activity
CEP66_RS20950	COG2814	Major facilitator Superfamily
CEP66_RS20960	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CEP66_RS20970	COG3591	Belongs to the peptidase S1B family
CEP66_RS20990	COG0628	permease
CEP66_RS20995	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CEP66_RS21000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CEP66_RS21015	COG0531	amino acid
CEP66_RS21025	COG3136	membrane protein required for alginate biosynthesis
CEP66_RS21030	COG0745	RESPONSE REGULATOR receiver
CEP66_RS21035	COG2205	protein histidine kinase activity
CEP66_RS21045	COG0114	fumarate hydratase activity
CEP66_RS21050	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS21050	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CEP66_RS21060	COG5339	Protein conserved in bacteria
CEP66_RS21065	COG1609	Transcriptional regulator
CEP66_RS21070	COG1263	PTS System
CEP66_RS21070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CEP66_RS21075	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CEP66_RS21090	COG0673	inositol 2-dehydrogenase activity
CEP66_RS21140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CEP66_RS21150	COG0625	glutathione transferase activity
CEP66_RS21155	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CEP66_RS21170	COG3895	Periplasmic Protein
CEP66_RS21195	COG1566	PFAM secretion protein HlyD family protein
CEP66_RS21210	COG4989	oxidoreductase activity
CEP66_RS21215	COG3313	Fe-S protein
CEP66_RS21220	COG1309	transcriptional regulator
CEP66_RS21225	COG1902	pentaerythritol trinitrate reductase activity
CEP66_RS21230	COG0346	lactoylglutathione lyase activity
CEP66_RS21240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CEP66_RS21245	COG0791	NLP P60 protein
CEP66_RS21250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CEP66_RS21255	COG2814	Major facilitator Superfamily
CEP66_RS21275	COG0583	DNA-binding transcription factor activity
CEP66_RS21280	COG2814	Major facilitator Superfamily
CEP66_RS21285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CEP66_RS21290	COG0307	riboflavin synthase, alpha
CEP66_RS21315	COG4771	TonB-dependent receptor
CEP66_RS21320	COG2819	hydrolase of the alpha beta superfamily
CEP66_RS21340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS21350	COG0765	amino acid transport
CEP66_RS21355	COG0765	amino acid transport
CEP66_RS21365	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CEP66_RS21370	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS21380	COG2414	aldehyde ferredoxin oxidoreductase
CEP66_RS21385	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS21395	COG1464	Belongs to the NlpA lipoprotein family
CEP66_RS21400	COG2011	ABC-type metal ion transport system permease component
CEP66_RS21415	COG0626	cystathionine gamma-synthase activity
CEP66_RS21435	COG1376	ErfK ybiS ycfS ynhG family protein
CEP66_RS21450	COG0719	Fe-S assembly protein
CEP66_RS21455	COG0396	ATPase activity
CEP66_RS21460	COG0719	Fe-S assembly protein
CEP66_RS21465	COG0316	Belongs to the HesB IscA family
CEP66_RS21485	COG2050	protein possibly involved in aromatic compounds catabolism
CEP66_RS21490	COG0277	FAD linked oxidase domain protein
CEP66_RS21490	COG0247	lactate metabolic process
CEP66_RS21495	COG0628	permease
CEP66_RS21505	COG0574	Belongs to the PEP-utilizing enzyme family
CEP66_RS21505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CEP66_RS21520	COG4256	Hemin uptake protein
CEP66_RS21535	COG0791	NLP P60 protein
CEP66_RS21545	COG0386	Belongs to the glutathione peroxidase family
CEP66_RS21605	COG3137	Salt-induced outer membrane protein
CEP66_RS21610	COG1105	Belongs to the carbohydrate kinase PfkB family
CEP66_RS21620	COG3001	Fructosamine kinase
CEP66_RS21630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CEP66_RS21635	COG1028	Short-chain dehydrogenase reductase Sdr
CEP66_RS21640	COG1988	membrane-bound metal-dependent
CEP66_RS21645	COG1823	symporter activity
CEP66_RS21660	COG1486	melibiose metabolic process
CEP66_RS21665	COG1917	Cupin 2, conserved barrel domain protein
CEP66_RS21665	COG2169	Transcriptional regulator
CEP66_RS21670	COG1447	Phosphotransferase system cellobiose-specific component IIA
CEP66_RS21675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP66_RS21680	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CEP66_RS21690	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CEP66_RS21715	COG3678	ATP-independent chaperone mediated protein folding
CEP66_RS21745	COG0708	Exodeoxyribonuclease III
CEP66_RS21755	COG4134	Bacterial extracellular solute-binding protein
CEP66_RS21760	COG4135	transport system, permease component
CEP66_RS21765	COG4136	ATPase activity
CEP66_RS21770	COG2897	thiosulfate sulfurtransferase activity
CEP66_RS21775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CEP66_RS21780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CEP66_RS21785	COG0494	nUDIX hydrolase
CEP66_RS21800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CEP66_RS21815	COG0778	Nitroreductase
CEP66_RS21820	COG0616	signal peptide processing
CEP66_RS21825	COG0252	asparaginase activity
CEP66_RS21830	COG1335	isochorismatase
CEP66_RS21835	COG3139	Protein of unknown function (DUF1315)
CEP66_RS21860	COG3713	MltA-interacting MipA family protein
CEP66_RS21865	COG2766	serine protein kinase
CEP66_RS21875	COG2226	methyltransferase
CEP66_RS21880	COG2199	diguanylate cyclase activity
CEP66_RS21885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CEP66_RS21895	COG2207	Transcriptional regulator
CEP66_RS21900	COG2807	transmembrane transport
CEP66_RS21905	COG0504	CTP synthase activity
CEP66_RS21910	COG3189	MarR family transcriptional regulator
CEP66_RS21915	COG3042	response to heat
CEP66_RS21930	COG2261	transglycosylase associated protein
CEP66_RS21935	COG3383	formate dehydrogenase (NAD+) activity
CEP66_RS21950	COG3615	Tellurite resistance protein tehB
CEP66_RS21960	COG3443	Belongs to the bacterial solute-binding protein 9 family
CEP66_RS21965	COG0243	molybdopterin cofactor binding
CEP66_RS21970	COG3005	denitrification pathway
CEP66_RS21980	COG1560	Kdo2-lipid A biosynthetic process
CEP66_RS21990	COG0538	isocitrate dehydrogenase activity
CEP66_RS21995	COG1187	pseudouridine synthase activity
CEP66_RS22015	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CEP66_RS22030	COG2850	peptidyl-arginine hydroxylation
CEP66_RS22050	COG1177	transmembrane transport
CEP66_RS22060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CEP66_RS22070	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEP66_RS22075	COG1136	(ABC) transporter
CEP66_RS22080	COG4591	ABC-type transport system involved in lipoprotein release permease component
CEP66_RS22085	COG4763	Acyl-transferase
CEP66_RS22090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CEP66_RS22095	COG1388	LysM domain
CEP66_RS22095	COG1376	ErfK ybiS ycfS ynhG family protein
CEP66_RS22105	COG1309	transcriptional regulator
CEP66_RS22110	COG3134	Outer membrane lipoprotein
CEP66_RS22115	COG1252	NADH dehydrogenase
CEP66_RS22140	COG5633	Lipoprotein
CEP66_RS22145	COG0537	adenosine 5'-monophosphoramidase activity
CEP66_RS22150	COG4773	Receptor
CEP66_RS22160	COG0084	hydrolase, TatD family'
CEP66_RS22165	COG0470	DNA polymerase III
CEP66_RS22175	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CEP66_RS22180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CEP66_RS22185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CEP66_RS22200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CEP66_RS22245	COG1530	ribonuclease E activity
CEP66_RS22255	COG1256	bacterial-type flagellum assembly
CEP66_RS22275	COG4786	Flagellar basal body rod
CEP66_RS22280	COG4787	bacterial-type flagellum-dependent cell motility
CEP66_RS22290	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CEP66_RS22295	COG1558	bacterial-type flagellum-dependent cell motility
CEP66_RS22335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CEP66_RS22345	COG2999	glutathione oxidoreductase activity
CEP66_RS22380	COG3038	cytochrome b561
CEP66_RS22385	COG2353	YceI-like domain
CEP66_RS22395	COG1560	Kdo2-lipid A biosynthetic process
CEP66_RS22410	COG5645	(Lipo)protein
CEP66_RS22430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEP66_RS22490	COG3381	protein complex oligomerization
CEP66_RS22530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CEP66_RS22530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CEP66_RS22530	COG0506	proline dehydrogenase activity
CEP66_RS22540	COG1309	transcriptional regulator
CEP66_RS22545	COG3729	General stress protein
CEP66_RS22575	COG1136	(ABC) transporter
CEP66_RS22575	COG0577	efflux transmembrane transporter activity
CEP66_RS22580	COG0577	efflux transmembrane transporter activity
CEP66_RS22580	COG1136	(ABC) transporter
CEP66_RS22585	COG0577	efflux transmembrane transporter activity
CEP66_RS22585	COG1136	(ABC) transporter
CEP66_RS22600	COG0672	)-iron permease
CEP66_RS22610	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CEP66_RS22615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CEP66_RS22620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CEP66_RS22620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CEP66_RS22625	COG4232	protein-disulfide reductase activity
CEP66_RS22645	COG3093	addiction module antidote protein HigA
CEP66_RS22650	COG3549	Plasmid maintenance system killer
CEP66_RS22655	COG0348	domain, Protein
CEP66_RS22665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEP66_RS22680	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CEP66_RS22685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CEP66_RS22695	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CEP66_RS22750	COG0670	Belongs to the BI1 family
CEP66_RS22755	COG2920	part of a sulfur-relay system
CEP66_RS22775	COG1832	CoA-binding protein
CEP66_RS22790	COG0210	DNA helicase
CEP66_RS22795	COG3304	Inner membrane component domain
CEP66_RS22800	COG1289	transmembrane transporter activity
CEP66_RS22805	COG3070	regulator of competence-specific genes
CEP66_RS22820	COG2885	chlorophyll binding
CEP66_RS22820	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CEP66_RS22830	COG1067	ATP-dependent peptidase activity
CEP66_RS22840	COG3130	regulation of translation
CEP66_RS22850	COG3009	Protein conserved in bacteria
CEP66_RS22855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CEP66_RS22855	COG3008	intermembrane lipid transfer
CEP66_RS22860	COG2995	paraquat-inducible protein a
CEP66_RS22865	COG0488	(ABC) transporter
CEP66_RS22875	COG3217	Mosc domain protein beta barrel domain protein
CEP66_RS22875	COG0633	Ferredoxin
CEP66_RS22895	COG0431	NADPH-dependent FMN reductase
CEP66_RS22900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CEP66_RS22910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CEP66_RS22920	COG0308	aminopeptidase N
CEP66_RS22945	COG1448	Aminotransferase
CEP66_RS22950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CEP66_RS22955	COG3108	Peptidase M15
CEP66_RS22965	COG2989	Protein conserved in bacteria
CEP66_RS22975	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CEP66_RS22985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CEP66_RS22995	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CEP66_RS23000	COG3173	Aminoglycoside phosphotransferase
CEP66_RS23015	COG3214	Protein conserved in bacteria
CEP66_RS23030	COG2333	competence protein COMEC
CEP66_RS23030	COG0658	competence protein
CEP66_RS23040	COG0539	negative regulation of cytoplasmic translation
CEP66_RS23065	COG1944	ATP diphosphatase activity
CEP66_RS23070	COG2116	formate transmembrane transporter activity
CEP66_RS23075	COG1882	Formate acetyltransferase
CEP66_RS23080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEP66_RS23085	COG1737	Transcriptional regulator
CEP66_RS23100	COG3959	Transketolase, thiamine diphosphate binding domain
CEP66_RS23105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CEP66_RS23110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CEP66_RS23120	COG1335	isochorismatase
CEP66_RS23125	COG3302	dmso reductase anchor subunit
CEP66_RS23130	COG0437	4 iron, 4 sulfur cluster binding
CEP66_RS23135	COG0243	molybdopterin cofactor binding
CEP66_RS23145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CEP66_RS23170	COG0492	ferredoxin-NADP+ reductase activity
CEP66_RS23175	COG4988	ABC transporter
CEP66_RS23180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CEP66_RS23200	COG0583	DNA-binding transcription factor activity
CEP66_RS23210	COG1335	isochorismatase
CEP66_RS23240	COG1203	CRISPR-associated helicase, Cas3
CEP66_RS23245	COG1518	maintenance of DNA repeat elements
CEP66_RS23250	COG0542	response to heat
CEP66_RS23260	COG1278	Cold shock
CEP66_RS23270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CEP66_RS23275	COG3593	DNA synthesis involved in DNA repair
CEP66_RS23285	COG2431	L-lysine efflux transmembrane transporter activity
CEP66_RS23295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CEP66_RS23305	COG0028	Belongs to the TPP enzyme family
CEP66_RS23310	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CEP66_RS23315	COG0702	epimerase
CEP66_RS23320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CEP66_RS23325	COG3023	N-Acetylmuramoyl-L-alanine amidase
CEP66_RS23360	COG1442	glycosyl transferase family 8
CEP66_RS23360	COG1216	Glycosyl transferase, family 2
CEP66_RS23365	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CEP66_RS23370	COG5301	cellulose 1,4-beta-cellobiosidase activity
CEP66_RS23450	COG0740	serine-type endopeptidase activity
CEP66_RS23485	COG3179	chitinase
CEP66_RS23500	COG0071	Belongs to the small heat shock protein (HSP20) family
CEP66_RS23510	COG0484	heat shock protein binding
CEP66_RS23525	COG0305	Participates in initiation and elongation during chromosome replication
CEP66_RS23530	COG1484	DNA-dependent DNA replication
CEP66_RS23535	COG1802	Transcriptional regulator
CEP66_RS23535	COG4626	Terminase
CEP66_RS23610	COG0582	viral genome integration into host DNA
CEP66_RS23620	COG1126	abc transporter atp-binding protein
CEP66_RS23625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS23630	COG4215	(ABC) transporter
CEP66_RS23635	COG4160	amino acid transport
CEP66_RS23640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS23645	COG5002	protein histidine kinase activity
CEP66_RS23650	COG0745	RESPONSE REGULATOR receiver
CEP66_RS23665	COG1177	transmembrane transport
CEP66_RS23670	COG1176	ABC-type spermidine putrescine transport system, permease component I
CEP66_RS23675	COG3842	ATPase activity
CEP66_RS23680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CEP66_RS23725	COG3226	Transcriptional regulator
CEP66_RS23730	COG0738	Major facilitator superfamily
CEP66_RS23735	COG0561	phosphatase activity
CEP66_RS23740	COG2814	Major facilitator Superfamily
CEP66_RS23745	COG0671	phosphoesterase, PA-phosphatase related
CEP66_RS23750	COG1349	DNA-binding transcription factor activity
CEP66_RS23755	COG1686	Belongs to the peptidase S11 family
CEP66_RS23760	COG0625	glutathione transferase activity
CEP66_RS23765	COG2133	pyrroloquinoline quinone binding
CEP66_RS23790	COG0747	negative chemotaxis
CEP66_RS23815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CEP66_RS23820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CEP66_RS23825	COG1882	Formate acetyltransferase
CEP66_RS23830	COG0561	phosphatase activity
CEP66_RS23840	COG1609	Transcriptional regulator
CEP66_RS23845	COG2271	Major facilitator Superfamily
CEP66_RS23855	COG0488	(ABC) transporter
CEP66_RS23860	COG1376	ErfK ybiS ycfS ynhG family protein
CEP66_RS23865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CEP66_RS23870	COG1321	iron dependent repressor
CEP66_RS23880	COG2194	sulfuric ester hydrolase activity
CEP66_RS23885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CEP66_RS23900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CEP66_RS23905	COG0765	amino acid transport
CEP66_RS23910	COG1126	abc transporter atp-binding protein
CEP66_RS23915	COG0668	transmembrane transport
CEP66_RS23930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CEP66_RS23940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CEP66_RS23950	COG3121	Chaperone
CEP66_RS23975	COG0513	Belongs to the DEAD box helicase family
CEP66_RS23980	COG1309	transcriptional regulator
CEP66_RS23990	COG1131	(ABC) transporter
CEP66_RS23995	COG0842	Transport permease protein
CEP66_RS24000	COG0842	Transport permease protein
CEP66_RS24010	COG3568	Endonuclease Exonuclease Phosphatase
CEP66_RS24015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CEP66_RS24020	COG0392	lysyltransferase activity
CEP66_RS24025	COG0670	Belongs to the BI1 family
CEP66_RS24030	COG0314	molybdopterin synthase activity
CEP66_RS24035	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CEP66_RS24045	COG0521	Mo-molybdopterin cofactor biosynthetic process
CEP66_RS24070	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CEP66_RS24095	COG1881	PFAM PEBP family protein
CEP66_RS24125	COG4677	pectinesterase activity
CEP66_RS24130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CEP66_RS24135	COG0471	metal ion transport
CEP66_RS24140	COG2828	Protein conserved in bacteria
CEP66_RS24145	COG0583	DNA-binding transcription factor activity
CEP66_RS24155	COG0561	phosphatase activity
CEP66_RS24165	COG4149	molybdate abc transporter
CEP66_RS24170	COG0725	ABC transporter, periplasmic molybdate-binding protein
CEP66_RS24180	COG2005	Transcriptional regulator
CEP66_RS24180	COG3585	molybdate ion transport
CEP66_RS24185	COG1119	ATPase activity
CEP66_RS24190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CEP66_RS24205	COG2017	converts alpha-aldose to the beta-anomer
CEP66_RS24220	COG1120	ATPase activity
CEP66_RS24225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CEP66_RS24240	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CEP66_RS24255	COG1230	cation diffusion facilitator family transporter
CEP66_RS24260	COG3201	nicotinamide mononucleotide transporter
CEP66_RS24295	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CEP66_RS24300	COG2885	chlorophyll binding
CEP66_RS24310	COG3064	Membrane
CEP66_RS24315	COG0848	biopolymer transport protein