locus-tag	class	description
E6P06_RS00015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E6P06_RS00100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E6P06_RS00160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E6P06_RS00235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6P06_RS00245	COG1902	pentaerythritol trinitrate reductase activity
E6P06_RS00250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
E6P06_RS00255	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS00320	COG1528	Iron-storage protein
E6P06_RS00325	COG3039	Transposase
E6P06_RS00380	COG1393	Belongs to the ArsC family
E6P06_RS00385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E6P06_RS00405	COG0431	NADPH-dependent FMN reductase
E6P06_RS00410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E6P06_RS00415	COG0148	phosphopyruvate hydratase activity
E6P06_RS00425	COG1227	inorganic diphosphatase activity
E6P06_RS00460	COG1342	Belongs to the UPF0251 family
E6P06_RS00475	COG0783	Belongs to the Dps family
E6P06_RS00480	COG0640	Transcriptional regulator
E6P06_RS00485	COG0446	pyridine nucleotide-disulphide oxidoreductase
E6P06_RS00505	COG0730	response to heat
E6P06_RS00580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E6P06_RS00585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E6P06_RS00600	COG3423	Transcriptional regulator
E6P06_RS00765	COG2974	May be involved in recombination
E6P06_RS00820	COG3039	Transposase
E6P06_RS00825	COG1802	Transcriptional regulator
E6P06_RS00905	COG0038	chloride channel
E6P06_RS00910	COG0671	phosphoesterase, PA-phosphatase related
E6P06_RS00915	COG1227	inorganic diphosphatase activity
E6P06_RS00925	COG0148	phosphopyruvate hydratase activity
E6P06_RS00930	COG0588	phosphoglycerate mutase activity
E6P06_RS00935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E6P06_RS00940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E6P06_RS00945	COG1193	negative regulation of DNA recombination
E6P06_RS00965	COG0840	transmembrane signaling receptor activity
E6P06_RS00980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E6P06_RS01100	COG0110	maltose O-acetyltransferase activity
E6P06_RS01120	COG0305	Participates in initiation and elongation during chromosome replication
E6P06_RS01140	COG2909	trisaccharide binding
E6P06_RS01145	COG1349	DNA-binding transcription factor activity
E6P06_RS01160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E6P06_RS01165	COG0058	SHG alpha-glucan phosphorylase activity
E6P06_RS01180	COG1523	belongs to the glycosyl hydrolase 13 family
E6P06_RS01190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E6P06_RS01195	COG3039	Transposase
E6P06_RS01240	COG1192	Involved in chromosome partitioning
E6P06_RS01285	COG5642	Protein of unknown function (DUF2384)
E6P06_RS01290	COG5654	RES domain protein
E6P06_RS01700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E6P06_RS01700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E6P06_RS01740	COG0210	DNA helicase
E6P06_RS01755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6P06_RS01815	COG3039	Transposase
E6P06_RS01850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E6P06_RS01855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E6P06_RS01945	COG0673	inositol 2-dehydrogenase activity
E6P06_RS01950	COG1324	tolerance protein
E6P06_RS02140	COG0616	signal peptide processing
E6P06_RS02170	COG1525	nuclease
E6P06_RS02200	COG1192	Involved in chromosome partitioning
E6P06_RS02420	COG3550	peptidyl-serine autophosphorylation
E6P06_RS02565	COG0789	Transcriptional regulator
E6P06_RS02600	COG1349	DNA-binding transcription factor activity
E6P06_RS02645	COG1192	Involved in chromosome partitioning
E6P06_RS02685	COG0484	heat shock protein binding
E6P06_RS02810	COG1192	Involved in chromosome partitioning
E6P06_RS02850	COG1011	Hydrolase
E6P06_RS02875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E6P06_RS02880	COG3041	Addiction module toxin RelE StbE family
E6P06_RS03015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E6P06_RS03055	COG0789	Transcriptional regulator
E6P06_RS03100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E6P06_RS03115	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
E6P06_RS03130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E6P06_RS03150	COG1136	(ABC) transporter
E6P06_RS03165	COG1309	transcriptional regulator
E6P06_RS03255	COG3344	reverse transcriptase
E6P06_RS03345	COG1192	Involved in chromosome partitioning
E6P06_RS03370	COG0625	glutathione transferase activity
E6P06_RS03375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E6P06_RS03390	COG0583	DNA-binding transcription factor activity
E6P06_RS03400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E6P06_RS03415	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E6P06_RS03435	COG1846	Transcriptional regulator
E6P06_RS03480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E6P06_RS03480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E6P06_RS03505	COG3312	ion transport
E6P06_RS03520	COG0716	FMN binding
E6P06_RS03525	COG1522	sequence-specific DNA binding
E6P06_RS03550	COG1869	D-ribose catabolic process
E6P06_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS03565	COG1879	ABC-type sugar transport system periplasmic component
E6P06_RS03570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS03575	COG1609	Transcriptional regulator
E6P06_RS03580	COG0477	Major facilitator Superfamily
E6P06_RS03585	COG2186	Transcriptional regulator
E6P06_RS03625	COG3085	chromosome segregation
E6P06_RS03645	COG3978	acetolactate synthase activity
E6P06_RS03650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E6P06_RS03660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E6P06_RS03680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E6P06_RS03700	COG3118	belongs to the thioredoxin family
E6P06_RS03710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E6P06_RS03715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E6P06_RS03730	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E6P06_RS03735	COG0456	acetyltransferase
E6P06_RS03740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E6P06_RS03745	COG2244	polysaccharide biosynthetic process
E6P06_RS03790	COG3071	HemY protein
E6P06_RS03795	COG2959	enzyme of heme biosynthesis
E6P06_RS03840	COG1011	Hydrolase
E6P06_RS03880	COG1280	lysine exporter protein (LysE YggA)
E6P06_RS03890	COG1280	lysine exporter protein (LysE YggA)
E6P06_RS03895	COG2267	carboxylic ester hydrolase activity
E6P06_RS03900	COG0561	phosphatase activity
E6P06_RS03905	COG0697	spore germination
E6P06_RS03910	COG0583	DNA-binding transcription factor activity
E6P06_RS03960	COG0805	protein transport
E6P06_RS03985	COG1940	carbohydrate kinase activity
E6P06_RS03990	COG1609	Transcriptional regulator
E6P06_RS04010	COG1739	Uncharacterized protein family UPF0029
E6P06_RS04050	COG1763	Mo-molybdopterin cofactor biosynthetic process
E6P06_RS04055	COG0746	molybdenum cofactor guanylyltransferase activity
E6P06_RS04060	COG3084	Protein conserved in bacteria
E6P06_RS04075	COG0204	Acyl-transferase
E6P06_RS04095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E6P06_RS04105	COG2204	response regulator
E6P06_RS04110	COG3852	Histidine kinase
E6P06_RS04145	COG1501	Belongs to the glycosyl hydrolase 31 family
E6P06_RS04150	COG2017	converts alpha-aldose to the beta-anomer
E6P06_RS04160	COG3684	Belongs to the aldolase LacD family
E6P06_RS04170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS04175	COG1349	DNA-binding transcription factor activity
E6P06_RS04180	COG1011	Hydrolase
E6P06_RS04190	COG1490	D-aminoacyl-tRNA deacylase activity
E6P06_RS04195	COG0456	acetyltransferase
E6P06_RS04210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E6P06_RS04225	COG2864	formate dehydrogenase
E6P06_RS04230	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS04260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS04260	COG3711	transcriptional antiterminator
E6P06_RS04265	COG1363	Peptidase, m42
E6P06_RS04270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS04270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS04275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS04285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E6P06_RS04300	COG1454	alcohol dehydrogenase
E6P06_RS04345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E6P06_RS04350	COG2258	MOSC domain
E6P06_RS04355	COG2205	protein histidine kinase activity
E6P06_RS04360	COG0745	RESPONSE REGULATOR receiver
E6P06_RS04365	COG3678	ATP-independent chaperone mediated protein folding
E6P06_RS04395	COG0471	metal ion transport
E6P06_RS04410	COG3152	Membrane
E6P06_RS04420	COG1494	fructose-1,6-bisphosphatase
E6P06_RS04430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E6P06_RS04435	COG3074	FtsZ-dependent cytokinesis
E6P06_RS04450	COG1575	Belongs to the MenA family. Type 1 subfamily
E6P06_RS04465	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E6P06_RS04470	COG1609	Transcriptional regulator
E6P06_RS04480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E6P06_RS04495	COG2211	Major facilitator Superfamily
E6P06_RS04505	COG0626	cystathionine gamma-synthase activity
E6P06_RS04510	COG0460	homoserine dehydrogenase
E6P06_RS04510	COG0527	aspartate kinase activity
E6P06_RS04520	COG0737	Belongs to the 5'-nucleotidase family
E6P06_RS04530	COG0583	DNA-binding transcription factor activity
E6P06_RS04535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E6P06_RS04550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E6P06_RS04555	COG0363	glucosamine-6-phosphate deaminase activity
E6P06_RS04565	COG1882	Formate acetyltransferase
E6P06_RS04570	COG1349	DNA-binding transcription factor activity
E6P06_RS04575	COG0371	Dehydrogenase
E6P06_RS04585	COG2207	Transcriptional regulator
E6P06_RS04620	COG0583	DNA-binding transcription factor activity
E6P06_RS04680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E6P06_RS04730	COG0250	Participates in transcription elongation, termination and antitermination
E6P06_RS04765	COG1447	Phosphotransferase system cellobiose-specific component IIA
E6P06_RS04775	COG1278	Cold shock
E6P06_RS04790	COG2104	thiamine diphosphate biosynthetic process
E6P06_RS04795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E6P06_RS04855	COG4191	Histidine kinase
E6P06_RS04865	COG0151	Belongs to the GarS family
E6P06_RS04900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E6P06_RS04930	COG0646	methionine synthase
E6P06_RS04930	COG1410	methionine synthase
E6P06_RS04965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E6P06_RS05005	COG1187	pseudouridine synthase activity
E6P06_RS05025	COG4650	regulator
E6P06_RS05035	COG3541	Predicted nucleotidyltransferase
E6P06_RS05040	COG0527	aspartate kinase activity
E6P06_RS05065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6P06_RS05070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
E6P06_RS05075	COG3223	Belongs to the PsiE family
E6P06_RS05080	COG1757	Na H antiporter
E6P06_RS05085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E6P06_RS05100	COG2182	Extracellular solute-binding protein
E6P06_RS05135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E6P06_RS05145	COG0534	Mate efflux family protein
E6P06_RS05150	COG3237	CsbD-like
E6P06_RS05155	COG0735	belongs to the Fur family
E6P06_RS05200	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E6P06_RS05205	COG5532	Uncharacterized conserved protein (DUF2303)
E6P06_RS05240	COG4626	Terminase
E6P06_RS05240	COG1802	Transcriptional regulator
E6P06_RS05245	COG4725	Belongs to the MT-A70-like family
E6P06_RS05250	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
E6P06_RS05265	COG1403	HNH endonuclease
E6P06_RS05270	COG0484	heat shock protein binding
E6P06_RS05290	COG3179	chitinase
E6P06_RS05320	COG0740	serine-type endopeptidase activity
E6P06_RS05360	COG1196	nuclear chromosome segregation
E6P06_RS05420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E6P06_RS05435	COG0305	Participates in initiation and elongation during chromosome replication
E6P06_RS05445	COG1448	Aminotransferase
E6P06_RS05450	COG3700	Belongs to the class B bacterial acid phosphatase family
E6P06_RS05455	COG2315	Protein conserved in bacteria
E6P06_RS05460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
E6P06_RS05470	COG0629	single-stranded DNA binding
E6P06_RS05485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E6P06_RS05495	COG0789	Transcriptional regulator
E6P06_RS05500	COG2252	PERMEase
E6P06_RS05505	COG0025	NhaP-type Na H and K H
E6P06_RS05510	COG0583	DNA-binding transcription factor activity
E6P06_RS05515	COG1380	Effector of murein hydrolase LrgA
E6P06_RS05520	COG1346	cytolysis
E6P06_RS05530	COG3162	membrane
E6P06_RS05545	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E6P06_RS05550	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS05555	COG3301	Polysulphide reductase, NrfD
E6P06_RS05575	COG3088	subunit of a heme lyase
E6P06_RS05580	COG4235	cytochrome complex assembly
E6P06_RS05585	COG1301	dicarboxylic acid transport
E6P06_RS05590	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
E6P06_RS05600	COG1538	Outer membrane efflux protein
E6P06_RS05605	COG1289	transmembrane transporter activity
E6P06_RS05610	COG1566	PFAM secretion protein HlyD family protein
E6P06_RS05620	COG2015	COG2015, Alkyl sulfatase and related hydrolases
E6P06_RS05650	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS05655	COG1129	ABC transporter
E6P06_RS05675	COG3549	Plasmid maintenance system killer
E6P06_RS05680	COG3093	addiction module antidote protein HigA
E6P06_RS05685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E6P06_RS05690	COG0456	acetyltransferase
E6P06_RS05700	COG3454	Phosphonate metabolism
E6P06_RS05705	COG4778	phosphonate C-P lyase system protein PhnL
E6P06_RS05710	COG4107	phosphonate C-P lyase system protein PhnK
E6P06_RS05715	COG3627	carbon phosphorus lyase activity
E6P06_RS05720	COG3626	phosphonate metabolism
E6P06_RS05725	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
E6P06_RS05730	COG3624	Phosphonate C-P lyase system protein PhnG
E6P06_RS05735	COG2188	Transcriptional regulator
E6P06_RS05740	COG3639	organic phosphonate transmembrane transporter activity
E6P06_RS05745	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
E6P06_RS05750	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
E6P06_RS05755	COG2764	glyoxalase bleomycin resistance protein dioxygenase
E6P06_RS05760	COG2824	Alkylphosphonate utilization operon protein PhnA
E6P06_RS05765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E6P06_RS05805	COG0531	amino acid
E6P06_RS05810	COG2207	Transcriptional regulator
E6P06_RS05815	COG1982	Orn Lys Arg decarboxylase major
E6P06_RS05820	COG2169	Transcriptional regulator
E6P06_RS05825	COG1486	melibiose metabolic process
E6P06_RS05830	COG2211	Major facilitator Superfamily
E6P06_RS05840	COG3647	Membrane
E6P06_RS05845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS05845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS05850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E6P06_RS05855	COG4565	transcriptional regulatory protein
E6P06_RS05860	COG3290	protein histidine kinase activity
E6P06_RS05890	COG0318	PFAM AMP-dependent synthetase and ligase
E6P06_RS05925	COG2378	regulation of single-species biofilm formation
E6P06_RS05930	COG4735	regulation of single-species biofilm formation
E6P06_RS05965	COG4974	Belongs to the 'phage' integrase family
E6P06_RS05985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E6P06_RS06035	COG2190	(PTS) system
E6P06_RS06035	COG1263	PTS System
E6P06_RS06035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS06040	COG0366	Alpha amylase catalytic
E6P06_RS06050	COG3039	Transposase
E6P06_RS06065	COG1309	transcriptional regulator
E6P06_RS06080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E6P06_RS06085	COG1027	Aspartate ammonia-lyase
E6P06_RS06090	COG3030	protein affecting phage T7 exclusion by the F plasmid
E6P06_RS06095	COG0531	amino acid
E6P06_RS06120	COG1509	lysine 2,3-aminomutase activity
E6P06_RS06175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E6P06_RS06180	COG1053	succinate dehydrogenase
E6P06_RS06195	COG3264	Mechanosensitive ion channel
E6P06_RS06195	COG1511	domain protein
E6P06_RS06230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E6P06_RS06235	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
E6P06_RS06235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E6P06_RS06240	COG0802	atpase or kinase
E6P06_RS06245	COG0860	N-Acetylmuramoyl-L-alanine amidase
E6P06_RS06260	COG1923	regulation of RNA biosynthetic process
E6P06_RS06265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E6P06_RS06270	COG0330	HflC and HflK could
E6P06_RS06275	COG0330	HflC and HflK could
E6P06_RS06280	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
E6P06_RS06295	COG0557	exoribonuclease II activity
E6P06_RS06300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6P06_RS06305	COG1960	acyl-CoA dehydrogenase activity
E6P06_RS06315	COG3650	response to hydrogen peroxide
E6P06_RS06320	COG1073	alpha beta
E6P06_RS06370	COG0730	response to heat
E6P06_RS06385	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E6P06_RS06400	COG3061	Opacity-associated protein A
E6P06_RS06405	COG0545	Peptidyl-prolyl cis-trans isomerase
E6P06_RS06410	COG1113	amino acid transport
E6P06_RS06425	COG0697	spore germination
E6P06_RS06435	COG0702	epimerase
E6P06_RS06440	COG1733	regulation of RNA biosynthetic process
E6P06_RS06450	COG1218	3'(2'),5'-bisphosphate nucleotidase
E6P06_RS06455	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
E6P06_RS06465	COG1253	flavin adenine dinucleotide binding
E6P06_RS06475	COG2211	Major facilitator Superfamily
E6P06_RS06490	COG0673	inositol 2-dehydrogenase activity
E6P06_RS06495	COG0673	inositol 2-dehydrogenase activity
E6P06_RS06500	COG1609	Transcriptional regulator
E6P06_RS06510	COG0729	surface antigen
E6P06_RS06515	COG2911	Protein conserved in bacteria
E6P06_RS06520	COG2105	PFAM AIG2 family protein
E6P06_RS06525	COG3157	Type VI secretion system effector, Hcp
E6P06_RS06540	COG1879	ABC-type sugar transport system periplasmic component
E6P06_RS06545	COG1129	ABC transporter
E6P06_RS06550	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS06555	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS06560	COG0840	transmembrane signaling receptor activity
E6P06_RS06570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E6P06_RS06580	COG0312	modulator of DNA gyrase
E6P06_RS06615	COG3964	amidohydrolase
E6P06_RS06630	COG3711	transcriptional antiterminator
E6P06_RS06630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS06635	COG3077	Addiction module antitoxin, RelB DinJ family
E6P06_RS06655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS06655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS06655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS06660	COG0366	Alpha amylase catalytic
E6P06_RS06665	COG0383	alpha-mannosidase activity
E6P06_RS06670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS06675	COG1737	Transcriptional regulator
E6P06_RS06685	COG0366	Alpha amylase catalytic
E6P06_RS06690	COG1263	PTS System
E6P06_RS06690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS06710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
E6P06_RS06760	COG1438	arginine binding
E6P06_RS06765	COG1288	antiporter activity
E6P06_RS06770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
E6P06_RS06780	COG2235	arginine
E6P06_RS06785	COG2731	YhcH YjgK YiaL family protein
E6P06_RS06815	COG0525	valine-tRNA ligase activity
E6P06_RS06820	COG2927	DNA polymerase III (CHI subunit)
E6P06_RS06830	COG0795	lipopolysaccharide-transporting ATPase activity
E6P06_RS06835	COG0795	lipopolysaccharide-transporting ATPase activity
E6P06_RS06840	COG0433	COG0433 Predicted ATPase
E6P06_RS06845	COG1064	alcohol dehydrogenase
E6P06_RS06855	COG0582	viral genome integration into host DNA
E6P06_RS06865	COG0732	type I restriction modification DNA specificity domain
E6P06_RS06875	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
E6P06_RS06940	COG3596	GTP binding
E6P06_RS06950	COG2003	Belongs to the UPF0758 family
E6P06_RS07015	COG1620	l-lactate permease
E6P06_RS07020	COG0247	lactate metabolic process
E6P06_RS07025	COG1139	Iron-sulfur cluster binding protein
E6P06_RS07030	COG1556	Lactate utilization protein
E6P06_RS07035	COG2610	gluconate transmembrane transporter activity
E6P06_RS07045	COG0246	Mannitol dehydrogenase
E6P06_RS07050	COG2186	Transcriptional regulator
E6P06_RS07060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E6P06_RS07070	COG0477	Major facilitator Superfamily
E6P06_RS07080	COG2733	membrane
E6P06_RS07085	COG0583	DNA-binding transcription factor activity
E6P06_RS07090	COG1301	dicarboxylic acid transport
E6P06_RS07095	COG0626	cystathionine gamma-synthase activity
E6P06_RS07120	COG5464	transposase or invertase
E6P06_RS07125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6P06_RS07130	COG5457	Domain of unknown function (DUF1127)
E6P06_RS07140	COG1566	PFAM secretion protein HlyD family protein
E6P06_RS07155	COG0732	type I restriction modification DNA specificity domain
E6P06_RS07175	COG0523	cobalamin synthesis protein
E6P06_RS07180	COG2879	small protein
E6P06_RS07185	COG1966	Carbon starvation protein
E6P06_RS07195	COG0840	transmembrane signaling receptor activity
E6P06_RS07205	COG2271	Major facilitator Superfamily
E6P06_RS07210	COG1802	Transcriptional regulator
E6P06_RS07215	COG1063	alcohol dehydrogenase
E6P06_RS07235	COG1484	DNA-dependent DNA replication
E6P06_RS07250	COG2966	Psort location CytoplasmicMembrane, score
E6P06_RS07255	COG2197	response regulator
E6P06_RS07260	COG2197	response regulator
E6P06_RS07265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E6P06_RS07270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6P06_RS07275	COG4114	ferric iron reductase
E6P06_RS07280	COG3706	GGDEF domain
E6P06_RS07310	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
E6P06_RS07315	COG0456	acetyltransferase
E6P06_RS07320	COG1011	Hydrolase
E6P06_RS07330	COG2823	Periplasmic or secreted lipoprotein
E6P06_RS07335	COG5487	UPF0391 membrane protein
E6P06_RS07340	COG4667	esterase of the alpha-beta hydrolase superfamily
E6P06_RS07345	COG0084	hydrolase, TatD family'
E6P06_RS07350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E6P06_RS07355	COG1328	CTP reductase activity
E6P06_RS07385	COG3726	membrane protein affecting hemolysin expression
E6P06_RS07390	COG0560	Phosphoserine phosphatase
E6P06_RS07405	COG0488	(ABC) transporter
E6P06_RS07410	COG0741	lytic transglycosylase activity
E6P06_RS07430	COG2207	Transcriptional regulator
E6P06_RS07430	COG3708	Transcriptional regulator
E6P06_RS07435	COG3045	CreA protein
E6P06_RS07440	COG0745	RESPONSE REGULATOR receiver
E6P06_RS07445	COG2205	protein histidine kinase activity
E6P06_RS07450	COG4452	Inner membrane protein CreD
E6P06_RS07455	COG0745	RESPONSE REGULATOR receiver
E6P06_RS07465	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
E6P06_RS07475	COG0527	aspartate kinase activity
E6P06_RS07475	COG0460	homoserine dehydrogenase
E6P06_RS07485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E6P06_RS07495	COG1115	amino acid carrier protein
E6P06_RS07505	COG0521	Mo-molybdopterin cofactor biosynthetic process
E6P06_RS07515	COG1584	GPR1 FUN34 yaaH family protein
E6P06_RS07520	COG4735	regulation of single-species biofilm formation
E6P06_RS07530	COG0443	Heat shock 70 kDa protein
E6P06_RS07545	COG3119	arylsulfatase activity
E6P06_RS07550	COG0641	radical SAM
E6P06_RS07565	COG0583	DNA-binding transcription factor activity
E6P06_RS07590	COG0196	riboflavin kinase activity
E6P06_RS07605	COG1047	Peptidyl-prolyl cis-trans
E6P06_RS07625	COG0505	Belongs to the CarA family
E6P06_RS07680	COG0644	oxidoreductase
E6P06_RS07690	COG2271	Major facilitator Superfamily
E6P06_RS07740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
E6P06_RS07750	COG0564	pseudouridine synthase activity
E6P06_RS07760	COG0417	DNA replication proofreading
E6P06_RS07765	COG0235	Class ii aldolase
E6P06_RS07785	COG0586	Pfam SNARE associated Golgi protein
E6P06_RS07795	COG1178	ABC-type Fe3 transport system permease component
E6P06_RS07815	COG2814	Major facilitator Superfamily
E6P06_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS07830	COG1609	Transcriptional regulator
E6P06_RS07865	COG0028	Belongs to the TPP enzyme family
E6P06_RS07895	COG0768	penicillin binding
E6P06_RS07900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E6P06_RS07905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E6P06_RS07915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E6P06_RS07920	COG0772	Belongs to the SEDS family
E6P06_RS07935	COG1181	Belongs to the D-alanine--D-alanine ligase family
E6P06_RS07945	COG0849	cell division
E6P06_RS07950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E6P06_RS07970	COG0494	nUDIX hydrolase
E6P06_RS07985	COG0237	dephospho-CoA kinase activity
E6P06_RS07995	COG1459	type II secretion system
E6P06_RS08000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E6P06_RS08005	COG4969	Belongs to the N-Me-Phe pilin family
E6P06_RS08020	COG3725	Membrane protein required for beta-lactamase induction
E6P06_RS08025	COG3940	Belongs to the glycosyl hydrolase 43 family
E6P06_RS08030	COG2211	Major facilitator Superfamily
E6P06_RS08045	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
E6P06_RS08050	COG0508	dehydrogenase complex catalyzes the overall conversion of
E6P06_RS08055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E6P06_RS08070	COG3064	Membrane
E6P06_RS08100	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E6P06_RS08105	COG0288	reversible hydration of carbon dioxide
E6P06_RS08110	COG1131	(ABC) transporter
E6P06_RS08115	COG0842	Transport permease protein
E6P06_RS08120	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS08125	COG0726	polysaccharide deacetylase
E6P06_RS08145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E6P06_RS08150	COG0617	tRNA 3'-terminal CCA addition
E6P06_RS08170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E6P06_RS08175	COG1643	Atp-dependent helicase
E6P06_RS08180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E6P06_RS08200	COG3039	Transposase
E6P06_RS08210	COG3188	usher protein
E6P06_RS08215	COG3539	Fimbrial protein
E6P06_RS08220	COG4774	siderophore transport
E6P06_RS08225	COG1120	ATPase activity
E6P06_RS08230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E6P06_RS08255	COG2860	membrane
E6P06_RS08280	COG3835	regulator
E6P06_RS08325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E6P06_RS08335	COG0575	Belongs to the CDS family
E6P06_RS08350	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
E6P06_RS08390	COG1982	Orn Lys Arg decarboxylase major
E6P06_RS08395	COG0346	lactoylglutathione lyase activity
E6P06_RS08405	COG4568	rho-dependent transcription termination
E6P06_RS08420	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E6P06_RS08425	COG3015	lipoprotein NlpE involved in copper resistance
E6P06_RS08435	COG1720	tRNA m6t6A37 methyltransferase activity
E6P06_RS08445	COG1464	Belongs to the NlpA lipoprotein family
E6P06_RS08450	COG2011	ABC-type metal ion transport system permease component
E6P06_RS08460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E6P06_RS08520	COG0583	DNA-binding transcription factor activity
E6P06_RS08525	COG2814	Major facilitator Superfamily
E6P06_RS08535	COG2226	methyltransferase
E6P06_RS08540	COG1388	LysM domain
E6P06_RS08540	COG0741	lytic transglycosylase activity
E6P06_RS08550	COG2226	methyltransferase
E6P06_RS08560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E6P06_RS08595	COG1263	PTS System
E6P06_RS08595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS08600	COG3711	transcriptional antiterminator
E6P06_RS08610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E6P06_RS08615	COG1960	acyl-CoA dehydrogenase activity
E6P06_RS08625	COG0121	glutamine amidotransferase
E6P06_RS08630	COG3034	peptidoglycan biosynthetic process
E6P06_RS08635	COG0791	NLP P60 protein
E6P06_RS08650	COG1684	flagellar biosynthetic protein fliR
E6P06_RS08655	COG1987	bacterial-type flagellum assembly
E6P06_RS08680	COG1677	Flagellar hook-basal body complex protein FliE
E6P06_RS08690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6P06_RS08735	COG2195	Cleaves the N-terminal amino acid of tripeptides
E6P06_RS08760	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
E6P06_RS08770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6P06_RS08810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E6P06_RS08830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E6P06_RS08835	COG1757	Na H antiporter
E6P06_RS08865	COG3039	Transposase
E6P06_RS08880	COG3039	Transposase
E6P06_RS08885	COG3706	GGDEF domain
E6P06_RS08890	COG1280	lysine exporter protein (LysE YggA)
E6P06_RS08900	COG3829	transcription factor binding
E6P06_RS08910	COG0372	Belongs to the citrate synthase family
E6P06_RS08915	COG2079	MmgE PrpD family protein
E6P06_RS08940	COG1609	Transcriptional regulator
E6P06_RS08945	COG2226	methyltransferase
E6P06_RS08955	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E6P06_RS08985	COG1414	Transcriptional regulator
E6P06_RS09020	COG2814	Major facilitator Superfamily
E6P06_RS09025	COG0833	amino acid
E6P06_RS09030	COG2040	homocysteine
E6P06_RS09035	COG3842	ATPase activity
E6P06_RS09045	COG1840	ABC-type Fe3 transport system, periplasmic component
E6P06_RS09050	COG2271	Major facilitator Superfamily
E6P06_RS09065	COG4521	taurine ABC transporter
E6P06_RS09070	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
E6P06_RS09075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6P06_RS09080	COG2175	clavaminate synthase activity
E6P06_RS09085	COG0113	porphobilinogen synthase activity
E6P06_RS09120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6P06_RS09125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E6P06_RS09130	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
E6P06_RS09150	COG1181	Belongs to the D-alanine--D-alanine ligase family
E6P06_RS09165	COG1785	Belongs to the alkaline phosphatase family
E6P06_RS09175	COG3706	GGDEF domain
E6P06_RS09180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E6P06_RS09200	COG4126	flavin adenine dinucleotide binding
E6P06_RS09215	COG1940	carbohydrate kinase activity
E6P06_RS09220	COG2814	Major facilitator Superfamily
E6P06_RS09225	COG0419	ATPase involved in DNA repair
E6P06_RS09230	COG0420	3'-5' exonuclease activity
E6P06_RS09240	COG5002	protein histidine kinase activity
E6P06_RS09260	COG0366	Alpha amylase catalytic
E6P06_RS09265	COG0583	DNA-binding transcription factor activity
E6P06_RS09270	COG1335	isochorismatase
E6P06_RS09280	COG1574	metal-dependent hydrolase with the TIM-barrel fold
E6P06_RS09285	COG0450	alkyl hydroperoxide reductase
E6P06_RS09295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E6P06_RS09305	COG1862	Preprotein translocase
E6P06_RS09310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E6P06_RS09315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E6P06_RS09335	COG4238	major outer membrane lipoprotein
E6P06_RS09345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E6P06_RS09345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E6P06_RS09360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E6P06_RS09365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E6P06_RS09370	COG0667	Aldo Keto reductase
E6P06_RS09380	COG0142	geranyltranstransferase activity
E6P06_RS09415	COG2814	Major facilitator Superfamily
E6P06_RS09425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
E6P06_RS09430	COG1845	cytochrome c oxidase, subunit III
E6P06_RS09435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E6P06_RS09440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
E6P06_RS09445	COG2223	nitrite transmembrane transporter activity
E6P06_RS09450	COG3056	Lipoprotein
E6P06_RS09455	COG0271	Belongs to the BolA IbaG family
E6P06_RS09480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E6P06_RS09485	COG0776	regulation of translation
E6P06_RS09490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E6P06_RS09495	COG1555	photosystem II stabilization
E6P06_RS09500	COG0824	Thioesterase
E6P06_RS09510	COG4533	DNA binding
E6P06_RS09530	COG1522	sequence-specific DNA binding
E6P06_RS09535	COG1132	(ABC) transporter
E6P06_RS09540	COG1132	(ABC) transporter
E6P06_RS09550	COG0347	Belongs to the P(II) protein family
E6P06_RS09555	COG0004	ammonium transporteR
E6P06_RS09560	COG1946	Acyl-CoA thioesterase
E6P06_RS09565	COG3126	Type III secretion system lipoprotein chaperone (YscW)
E6P06_RS09570	COG3695	enzyme binding
E6P06_RS09590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6P06_RS09595	COG2364	Membrane
E6P06_RS09600	COG5507	3-demethylubiquinone-9 3-methyltransferase
E6P06_RS09605	COG4943	cyclic-guanylate-specific phosphodiesterase activity
E6P06_RS09625	COG0110	maltose O-acetyltransferase activity
E6P06_RS09640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6P06_RS09645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS09650	COG1309	transcriptional regulator
E6P06_RS09655	COG1196	nuclear chromosome segregation
E6P06_RS09655	COG3264	Mechanosensitive ion channel
E6P06_RS09665	COG3923	Primosomal replication protein n
E6P06_RS09670	COG2832	Protein of unknown function (DUF454)
E6P06_RS09715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS09720	COG4651	solute:proton antiporter activity
E6P06_RS09720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E6P06_RS09725	COG2223	nitrite transmembrane transporter activity
E6P06_RS09735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E6P06_RS09740	COG3735	TraB family
E6P06_RS09755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS09765	COG3721	Heme iron utilization protein
E6P06_RS09775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E6P06_RS09780	COG4771	TonB-dependent receptor
E6P06_RS09800	COG1585	Membrane protein implicated in regulation of membrane protease activity
E6P06_RS09805	COG0330	HflC and HflK could
E6P06_RS09810	COG4619	ABC transporter
E6P06_RS09815	COG0390	transport system, permease component
E6P06_RS09820	COG3118	belongs to the thioredoxin family
E6P06_RS09825	COG0300	oxidoreductase activity
E6P06_RS09830	COG2755	lipolytic protein G-D-S-L family
E6P06_RS09835	COG4181	ATPase activity
E6P06_RS09840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
E6P06_RS09845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E6P06_RS09850	COG1464	Belongs to the NlpA lipoprotein family
E6P06_RS09870	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E6P06_RS09875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E6P06_RS09885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E6P06_RS09895	COG1988	membrane-bound metal-dependent
E6P06_RS09900	COG2501	S4 domain
E6P06_RS09960	COG2205	protein histidine kinase activity
E6P06_RS09960	COG0784	Response regulator, receiver
E6P06_RS09960	COG2198	Histidine kinase
E6P06_RS09965	COG1879	ABC-type sugar transport system periplasmic component
E6P06_RS09970	COG0745	RESPONSE REGULATOR receiver
E6P06_RS09975	COG3005	denitrification pathway
E6P06_RS09990	COG0321	lipoyl(octanoyl) transferase activity
E6P06_RS09990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E6P06_RS10000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E6P06_RS10005	COG1215	transferase activity, transferring glycosyl groups
E6P06_RS10105	COG5002	protein histidine kinase activity
E6P06_RS10110	COG0745	RESPONSE REGULATOR receiver
E6P06_RS10115	COG1538	Outer membrane efflux protein
E6P06_RS10120	COG3039	Transposase
E6P06_RS10125	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS10130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS10135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6P06_RS10140	COG2207	Transcriptional regulator
E6P06_RS10145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E6P06_RS10155	COG3059	membrane
E6P06_RS10175	COG3300	MHYT domain
E6P06_RS10175	COG5001	Diguanylate cyclase
E6P06_RS10195	COG1113	amino acid transport
E6P06_RS10200	COG0668	transmembrane transport
E6P06_RS10210	COG2315	Protein conserved in bacteria
E6P06_RS10275	COG2977	Belongs to the P-Pant transferase superfamily
E6P06_RS10280	COG4771	TonB-dependent receptor
E6P06_RS10285	COG2382	esterase
E6P06_RS10290	COG3251	PFAM MbtH domain protein
E6P06_RS10295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E6P06_RS10295	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
E6P06_RS10305	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E6P06_RS10310	COG1120	ATPase activity
E6P06_RS10315	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS10320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS10330	COG4592	Periplasmic binding protein
E6P06_RS10335	COG1169	isochorismate synthase
E6P06_RS10340	COG1021	2,3-dihydroxybenzoate-AMP ligase
E6P06_RS10345	COG3433	isochorismatase activity
E6P06_RS10345	COG1535	isochorismatase
E6P06_RS10350	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS10360	COG1966	Carbon starvation protein
E6P06_RS10365	COG2879	small protein
E6P06_RS10370	COG0371	Dehydrogenase
E6P06_RS10375	COG0436	Aminotransferase
E6P06_RS10380	COG1475	DNA binding
E6P06_RS10385	COG3969	phosphoadenosine phosphosulfate
E6P06_RS10390	COG0583	DNA-binding transcription factor activity
E6P06_RS10395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E6P06_RS10405	COG3634	alkyl hydroperoxide reductase activity
E6P06_RS10415	COG0243	molybdopterin cofactor binding
E6P06_RS10435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E6P06_RS10450	COG3719	Belongs to the RNase T2 family
E6P06_RS10455	COG0471	metal ion transport
E6P06_RS10470	COG3051	citrate lyase alpha subunit
E6P06_RS10475	COG2301	Belongs to the HpcH HpaI aldolase family
E6P06_RS10485	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
E6P06_RS10490	COG3290	protein histidine kinase activity
E6P06_RS10495	COG4565	transcriptional regulatory protein
E6P06_RS10500	COG3069	C4-dicarboxylate transmembrane transporter activity
E6P06_RS10520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E6P06_RS10545	COG1686	Belongs to the peptidase S11 family
E6P06_RS10550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
E6P06_RS10555	COG0772	Belongs to the SEDS family
E6P06_RS10560	COG0768	penicillin binding
E6P06_RS10570	COG0799	negative regulation of ribosome biogenesis
E6P06_RS10580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E6P06_RS10590	COG1466	dna polymerase III delta subunit
E6P06_RS10605	COG2888	peptidyl-tyrosine sulfation
E6P06_RS10615	COG1126	abc transporter atp-binding protein
E6P06_RS10620	COG0765	amino acid transport
E6P06_RS10625	COG0765	amino acid transport
E6P06_RS10640	COG4535	Mg2 and Co2 transporter CorC
E6P06_RS10650	COG1702	phosphate starvation-inducible protein PhoH
E6P06_RS10665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6P06_RS10705	COG0367	asparagine synthase
E6P06_RS10715	COG0647	UMP catabolic process
E6P06_RS10720	COG1940	carbohydrate kinase activity
E6P06_RS10720	COG1846	Transcriptional regulator
E6P06_RS10725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E6P06_RS10735	COG1263	PTS System
E6P06_RS10735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS10735	COG2190	(PTS) system
E6P06_RS10765	COG1053	succinate dehydrogenase
E6P06_RS10770	COG0583	DNA-binding transcription factor activity
E6P06_RS10775	COG0735	belongs to the Fur family
E6P06_RS10785	COG0716	FMN binding
E6P06_RS10795	COG0596	Alpha beta hydrolase
E6P06_RS10800	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
E6P06_RS10805	COG0033	Phosphoglucomutase
E6P06_RS10810	COG0745	RESPONSE REGULATOR receiver
E6P06_RS10815	COG2205	protein histidine kinase activity
E6P06_RS10845	COG3272	Protein of unknown function (DUF1722)
E6P06_RS10870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E6P06_RS10875	COG1984	allophanate hydrolase subunit 2
E6P06_RS10905	COG3180	Ammonia monooxygenase
E6P06_RS10910	COG4316	Uncharacterized protein conserved in bacteria (DUF2251)
E6P06_RS10925	COG3157	Type VI secretion system effector, Hcp
E6P06_RS10935	COG2009	succinate dehydrogenase
E6P06_RS10940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
E6P06_RS10945	COG1053	succinate dehydrogenase
E6P06_RS10950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E6P06_RS10955	COG0567	Dehydrogenase, E1 component
E6P06_RS10960	COG0508	dehydrogenase complex catalyzes the overall conversion of
E6P06_RS10970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E6P06_RS10980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E6P06_RS10980	COG1648	precorrin-2 dehydrogenase activity
E6P06_RS10985	COG0583	DNA-binding transcription factor activity
E6P06_RS10995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS10995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS11005	COG1301	dicarboxylic acid transport
E6P06_RS11020	COG3799	methylaspartate ammonia-lyase activity
E6P06_RS11025	COG4865	methylaspartate mutase activity
E6P06_RS11035	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E6P06_RS11040	COG1271	oxidase subunit
E6P06_RS11045	COG1294	oxidase, subunit
E6P06_RS11050	COG4890	Cyd operon protein YbgT
E6P06_RS11055	COG3790	cyd operon protein YbgE
E6P06_RS11060	COG0824	Thioesterase
E6P06_RS11065	COG0811	peptide transport
E6P06_RS11070	COG0848	biopolymer transport protein
E6P06_RS11075	COG3064	Membrane
E6P06_RS11085	COG2885	chlorophyll binding
E6P06_RS11090	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
E6P06_RS11130	COG3201	nicotinamide mononucleotide transporter
E6P06_RS11135	COG1230	cation diffusion facilitator family transporter
E6P06_RS11145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E6P06_RS11155	COG2017	converts alpha-aldose to the beta-anomer
E6P06_RS11165	COG1085	galactose-1-phosphate uridylyltransferase
E6P06_RS11170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E6P06_RS11175	COG1119	ATPase activity
E6P06_RS11180	COG3585	molybdate ion transport
E6P06_RS11180	COG2005	Transcriptional regulator
E6P06_RS11190	COG0725	ABC transporter, periplasmic molybdate-binding protein
E6P06_RS11195	COG4149	molybdate abc transporter
E6P06_RS11205	COG0561	phosphatase activity
E6P06_RS11225	COG4677	pectinesterase activity
E6P06_RS11255	COG1881	PFAM PEBP family protein
E6P06_RS11260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E6P06_RS11280	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E6P06_RS11315	COG0521	Mo-molybdopterin cofactor biosynthetic process
E6P06_RS11325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
E6P06_RS11330	COG0314	molybdopterin synthase activity
E6P06_RS11335	COG0670	Belongs to the BI1 family
E6P06_RS11340	COG0392	lysyltransferase activity
E6P06_RS11345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6P06_RS11350	COG3568	Endonuclease Exonuclease Phosphatase
E6P06_RS11360	COG0842	Transport permease protein
E6P06_RS11365	COG0842	Transport permease protein
E6P06_RS11370	COG1131	(ABC) transporter
E6P06_RS11380	COG1309	transcriptional regulator
E6P06_RS11385	COG0513	Belongs to the DEAD box helicase family
E6P06_RS11395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E6P06_RS11400	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
E6P06_RS11410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E6P06_RS11420	COG4774	siderophore transport
E6P06_RS11435	COG0668	transmembrane transport
E6P06_RS11440	COG1126	abc transporter atp-binding protein
E6P06_RS11445	COG0765	amino acid transport
E6P06_RS11450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS11465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E6P06_RS11475	COG2194	sulfuric ester hydrolase activity
E6P06_RS11490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E6P06_RS11495	COG1376	ErfK ybiS ycfS ynhG family protein
E6P06_RS11500	COG0488	(ABC) transporter
E6P06_RS11510	COG0561	phosphatase activity
E6P06_RS11515	COG1882	Formate acetyltransferase
E6P06_RS11520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E6P06_RS11525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E6P06_RS11530	COG5464	transposase or invertase
E6P06_RS11535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E6P06_RS11540	COG0303	'Molybdopterin
E6P06_RS11550	COG1446	asparaginase
E6P06_RS11585	COG2133	pyrroloquinoline quinone binding
E6P06_RS11590	COG0625	glutathione transferase activity
E6P06_RS11595	COG1686	Belongs to the peptidase S11 family
E6P06_RS11600	COG1349	DNA-binding transcription factor activity
E6P06_RS11605	COG0671	phosphoesterase, PA-phosphatase related
E6P06_RS11610	COG2814	Major facilitator Superfamily
E6P06_RS11620	COG0561	phosphatase activity
E6P06_RS11625	COG0738	Major facilitator superfamily
E6P06_RS11630	COG3226	Transcriptional regulator
E6P06_RS11635	COG0583	DNA-binding transcription factor activity
E6P06_RS11695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E6P06_RS11700	COG3842	ATPase activity
E6P06_RS11705	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6P06_RS11710	COG1177	transmembrane transport
E6P06_RS11735	COG1335	isochorismatase
E6P06_RS11745	COG0583	DNA-binding transcription factor activity
E6P06_RS11750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E6P06_RS11765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E6P06_RS11770	COG4988	ABC transporter
E6P06_RS11775	COG0492	ferredoxin-NADP+ reductase activity
E6P06_RS11785	COG1674	ftsk spoiiie
E6P06_RS11785	COG1178	ABC-type Fe3 transport system permease component
E6P06_RS11795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E6P06_RS11810	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS11815	COG3302	dmso reductase anchor subunit
E6P06_RS11820	COG1335	isochorismatase
E6P06_RS11830	COG0531	amino acid
E6P06_RS11835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E6P06_RS11840	COG1882	Formate acetyltransferase
E6P06_RS11845	COG2116	formate transmembrane transporter activity
E6P06_RS11850	COG1944	ATP diphosphatase activity
E6P06_RS11855	COG2323	membrane
E6P06_RS11870	COG0501	Belongs to the peptidase M48B family
E6P06_RS11880	COG0539	negative regulation of cytoplasmic translation
E6P06_RS11885	COG0776	regulation of translation
E6P06_RS11890	COG0658	competence protein
E6P06_RS11890	COG2333	competence protein COMEC
E6P06_RS11905	COG3214	Protein conserved in bacteria
E6P06_RS11920	COG3173	Aminoglycoside phosphotransferase
E6P06_RS11925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E6P06_RS11930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
E6P06_RS11940	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
E6P06_RS11950	COG2989	Protein conserved in bacteria
E6P06_RS11955	COG3108	Peptidase M15
E6P06_RS11960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E6P06_RS11965	COG1448	Aminotransferase
E6P06_RS11985	COG0308	aminopeptidase N
E6P06_RS11990	COG1116	anion transmembrane transporter activity
E6P06_RS11995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E6P06_RS12005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E6P06_RS12010	COG0431	NADPH-dependent FMN reductase
E6P06_RS12025	COG0633	Ferredoxin
E6P06_RS12025	COG3217	Mosc domain protein beta barrel domain protein
E6P06_RS12035	COG0488	(ABC) transporter
E6P06_RS12040	COG2995	paraquat-inducible protein a
E6P06_RS12045	COG3008	intermembrane lipid transfer
E6P06_RS12045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E6P06_RS12050	COG3009	Protein conserved in bacteria
E6P06_RS12055	COG3130	regulation of translation
E6P06_RS12065	COG1067	ATP-dependent peptidase activity
E6P06_RS12085	COG3070	regulator of competence-specific genes
E6P06_RS12090	COG1289	transmembrane transporter activity
E6P06_RS12095	COG3304	Inner membrane component domain
E6P06_RS12100	COG0210	DNA helicase
E6P06_RS12115	COG1832	CoA-binding protein
E6P06_RS12140	COG0670	Belongs to the BI1 family
E6P06_RS12160	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
E6P06_RS12160	COG2857	Cytochrome c1
E6P06_RS12165	COG0723	plastoquinol--plastocyanin reductase activity
E6P06_RS12175	COG1120	ATPase activity
E6P06_RS12180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS12200	COG0813	purine-nucleoside phosphorylase activity
E6P06_RS12250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E6P06_RS12250	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E6P06_RS12255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E6P06_RS12265	COG0640	Transcriptional regulator
E6P06_RS12285	COG3729	General stress protein
E6P06_RS12295	COG1309	transcriptional regulator
E6P06_RS12300	COG3755	Protein conserved in bacteria
E6P06_RS12305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E6P06_RS12305	COG0506	proline dehydrogenase activity
E6P06_RS12305	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
E6P06_RS12310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E6P06_RS12330	COG1702	phosphate starvation-inducible protein PhoH
E6P06_RS12335	COG2990	Protein conserved in bacteria
E6P06_RS12345	COG2962	Rard protein
E6P06_RS12390	COG3381	protein complex oligomerization
E6P06_RS12445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6P06_RS12465	COG5645	(Lipo)protein
E6P06_RS12495	COG1560	Kdo2-lipid A biosynthetic process
E6P06_RS12510	COG3038	cytochrome b561
E6P06_RS12550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6P06_RS12590	COG1558	bacterial-type flagellum-dependent cell motility
E6P06_RS12605	COG4787	bacterial-type flagellum-dependent cell motility
E6P06_RS12610	COG4786	Flagellar basal body rod
E6P06_RS12640	COG2814	Major facilitator Superfamily
E6P06_RS12645	COG0583	DNA-binding transcription factor activity
E6P06_RS12650	COG1530	ribonuclease E activity
E6P06_RS12655	COG0564	pseudouridine synthase activity
E6P06_RS12665	COG1399	metal-binding, possibly nucleic acid-binding protein
E6P06_RS12700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E6P06_RS12705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E6P06_RS12710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E6P06_RS12720	COG0470	DNA polymerase III
E6P06_RS12725	COG0084	hydrolase, TatD family'
E6P06_RS12740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E6P06_RS12745	COG0477	Major facilitator Superfamily
E6P06_RS12770	COG1120	ATPase activity
E6P06_RS12775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS12780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS12785	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
E6P06_RS12790	COG4772	TonB-dependent receptor
E6P06_RS12795	COG3712	iron ion homeostasis
E6P06_RS12800	COG1595	DNA-templated transcription, initiation
E6P06_RS12820	COG0583	DNA-binding transcription factor activity
E6P06_RS12830	COG0534	Mate efflux family protein
E6P06_RS12840	COG2030	dehydratase
E6P06_RS12840	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS12845	COG3396	Phenylacetate-CoA oxygenase
E6P06_RS12850	COG3460	Phenylacetate-CoA oxygenase
E6P06_RS12855	COG3396	Phenylacetate-CoA oxygenase
E6P06_RS12860	COG2151	metal-sulfur cluster biosynthetic enzyme
E6P06_RS12865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6P06_RS12870	COG1024	Enoyl-CoA hydratase
E6P06_RS12875	COG1024	Enoyl-CoA hydratase
E6P06_RS12880	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6P06_RS12885	COG2050	protein possibly involved in aromatic compounds catabolism
E6P06_RS12890	COG0183	Belongs to the thiolase family
E6P06_RS12895	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
E6P06_RS12900	COG3327	negative regulation of DNA-templated transcription, initiation
E6P06_RS12905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E6P06_RS12910	COG4773	Receptor
E6P06_RS12915	COG0537	adenosine 5'-monophosphoramidase activity
E6P06_RS12920	COG5633	Lipoprotein
E6P06_RS12945	COG1252	NADH dehydrogenase
E6P06_RS12950	COG3134	Outer membrane lipoprotein
E6P06_RS12960	COG1309	transcriptional regulator
E6P06_RS12970	COG1388	LysM domain
E6P06_RS12970	COG1376	ErfK ybiS ycfS ynhG family protein
E6P06_RS12975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E6P06_RS12980	COG4763	Acyl-transferase
E6P06_RS12985	COG4591	ABC-type transport system involved in lipoprotein release permease component
E6P06_RS12990	COG1136	(ABC) transporter
E6P06_RS12995	COG4591	ABC-type transport system involved in lipoprotein release permease component
E6P06_RS13005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E6P06_RS13015	COG1177	transmembrane transport
E6P06_RS13035	COG2850	peptidyl-arginine hydroxylation
E6P06_RS13060	COG4221	oxidoreductase activity
E6P06_RS13070	COG0318	PFAM AMP-dependent synthetase and ligase
E6P06_RS13070	COG0204	Acyl-transferase
E6P06_RS13080	COG3038	cytochrome b561
E6P06_RS13085	COG2135	peptidase activity
E6P06_RS13090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E6P06_RS13120	COG0538	isocitrate dehydrogenase activity
E6P06_RS13135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
E6P06_RS13140	COG0431	NADPH-dependent FMN reductase
E6P06_RS13160	COG0538	isocitrate dehydrogenase activity
E6P06_RS13180	COG2200	EAL domain
E6P06_RS13195	COG4771	TonB-dependent receptor
E6P06_RS13200	COG0747	negative chemotaxis
E6P06_RS13205	COG0601	transmembrane transport
E6P06_RS13210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6P06_RS13220	COG1124	(ABC) transporter
E6P06_RS13225	COG3443	Belongs to the bacterial solute-binding protein 9 family
E6P06_RS13235	COG3615	Tellurite resistance protein tehB
E6P06_RS13255	COG3383	formate dehydrogenase (NAD+) activity
E6P06_RS13260	COG2261	transglycosylase associated protein
E6P06_RS13275	COG2203	Gaf domain
E6P06_RS13275	COG2199	diguanylate cyclase activity
E6P06_RS13280	COG3042	response to heat
E6P06_RS13285	COG3189	MarR family transcriptional regulator
E6P06_RS13290	COG0504	CTP synthase activity
E6P06_RS13295	COG2807	transmembrane transport
E6P06_RS13300	COG2207	Transcriptional regulator
E6P06_RS13310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E6P06_RS13315	COG2199	diguanylate cyclase activity
E6P06_RS13320	COG2226	methyltransferase
E6P06_RS13330	COG2766	serine protein kinase
E6P06_RS13335	COG3713	MltA-interacting MipA family protein
E6P06_RS13340	COG0656	L-ascorbic acid biosynthetic process
E6P06_RS13360	COG3139	Protein of unknown function (DUF1315)
E6P06_RS13375	COG1063	alcohol dehydrogenase
E6P06_RS13380	COG2271	Major facilitator Superfamily
E6P06_RS13385	COG1063	alcohol dehydrogenase
E6P06_RS13390	COG0191	fructose-bisphosphate aldolase activity
E6P06_RS13395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS13400	COG0667	Aldo Keto reductase
E6P06_RS13405	COG1349	DNA-binding transcription factor activity
E6P06_RS13410	COG2814	Major facilitator Superfamily
E6P06_RS13415	COG1335	isochorismatase
E6P06_RS13420	COG0252	asparaginase activity
E6P06_RS13425	COG0616	signal peptide processing
E6P06_RS13430	COG0778	Nitroreductase
E6P06_RS13440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E6P06_RS13455	COG0494	nUDIX hydrolase
E6P06_RS13460	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6P06_RS13465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E6P06_RS13470	COG2897	thiosulfate sulfurtransferase activity
E6P06_RS13475	COG4136	ATPase activity
E6P06_RS13480	COG4135	transport system, permease component
E6P06_RS13485	COG4134	Bacterial extracellular solute-binding protein
E6P06_RS13490	COG0398	Pfam SNARE associated Golgi protein
E6P06_RS13495	COG0398	Pfam SNARE associated Golgi protein
E6P06_RS13500	COG0708	Exodeoxyribonuclease III
E6P06_RS13535	COG3678	ATP-independent chaperone mediated protein folding
E6P06_RS13545	COG0322	excinuclease ABC activity
E6P06_RS13555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6P06_RS13560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6P06_RS13565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E6P06_RS13570	COG1447	Phosphotransferase system cellobiose-specific component IIA
E6P06_RS13575	COG1917	Cupin 2, conserved barrel domain protein
E6P06_RS13575	COG2169	Transcriptional regulator
E6P06_RS13580	COG1486	melibiose metabolic process
E6P06_RS13590	COG0753	catalase activity
E6P06_RS13600	COG1823	symporter activity
E6P06_RS13605	COG1988	membrane-bound metal-dependent
E6P06_RS13610	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS13615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6P06_RS13625	COG3001	Fructosamine kinase
E6P06_RS13630	COG1105	Belongs to the carbohydrate kinase PfkB family
E6P06_RS13635	COG3137	Salt-induced outer membrane protein
E6P06_RS13700	COG0463	Glycosyl transferase, family 2
E6P06_RS13705	COG2246	polysaccharide biosynthetic process
E6P06_RS13725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E6P06_RS13760	COG0386	Belongs to the glutathione peroxidase family
E6P06_RS13770	COG0791	NLP P60 protein
E6P06_RS13790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS13795	COG4558	Periplasmic binding protein
E6P06_RS13800	COG3720	iron ion transport
E6P06_RS13805	COG4771	TonB-dependent receptor
E6P06_RS13810	COG4256	Hemin uptake protein
E6P06_RS13815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E6P06_RS13825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E6P06_RS13825	COG0574	Belongs to the PEP-utilizing enzyme family
E6P06_RS13830	COG0318	PFAM AMP-dependent synthetase and ligase
E6P06_RS13835	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
E6P06_RS13840	COG0644	oxidoreductase
E6P06_RS13845	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E6P06_RS13850	COG2086	electron transfer activity
E6P06_RS13855	COG2207	Transcriptional regulator
E6P06_RS13855	COG1917	Cupin 2, conserved barrel domain protein
E6P06_RS13860	COG1960	acyl-CoA dehydrogenase activity
E6P06_RS13865	COG4670	ketone body catabolic process
E6P06_RS13880	COG2271	Major facilitator Superfamily
E6P06_RS13885	COG0738	Major facilitator superfamily
E6P06_RS13905	COG0628	permease
E6P06_RS13910	COG0277	FAD linked oxidase domain protein
E6P06_RS13910	COG0247	lactate metabolic process
E6P06_RS13915	COG2050	protein possibly involved in aromatic compounds catabolism
E6P06_RS13930	COG0583	DNA-binding transcription factor activity
E6P06_RS13935	COG0316	Belongs to the HesB IscA family
E6P06_RS13940	COG0719	Fe-S assembly protein
E6P06_RS13945	COG0396	ATPase activity
E6P06_RS13950	COG0719	Fe-S assembly protein
E6P06_RS13965	COG1376	ErfK ybiS ycfS ynhG family protein
E6P06_RS13980	COG0531	amino acid
E6P06_RS13985	COG2267	carboxylic ester hydrolase activity
E6P06_RS13995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS14005	COG2011	ABC-type metal ion transport system permease component
E6P06_RS14010	COG1464	Belongs to the NlpA lipoprotein family
E6P06_RS14060	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS14065	COG2414	aldehyde ferredoxin oxidoreductase
E6P06_RS14075	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS14080	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
E6P06_RS14090	COG0765	amino acid transport
E6P06_RS14105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS14115	COG1113	amino acid transport
E6P06_RS14130	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS14140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E6P06_RS14155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E6P06_RS14170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E6P06_RS14175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS14180	COG1120	ATPase activity
E6P06_RS14200	COG1794	racemase activity, acting on amino acids and derivatives
E6P06_RS14205	COG0583	DNA-binding transcription factor activity
E6P06_RS14225	COG0582	viral genome integration into host DNA
E6P06_RS14235	COG0583	DNA-binding transcription factor activity
E6P06_RS14270	COG0628	permease
E6P06_RS14275	COG0386	Belongs to the glutathione peroxidase family
E6P06_RS14300	COG0251	oxidation-reduction process
E6P06_RS14325	COG0307	riboflavin synthase, alpha
E6P06_RS14330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E6P06_RS14335	COG2814	Major facilitator Superfamily
E6P06_RS14340	COG0583	DNA-binding transcription factor activity
E6P06_RS14355	COG2814	Major facilitator Superfamily
E6P06_RS14360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E6P06_RS14365	COG0791	NLP P60 protein
E6P06_RS14370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
E6P06_RS14380	COG0346	lactoylglutathione lyase activity
E6P06_RS14385	COG1902	pentaerythritol trinitrate reductase activity
E6P06_RS14390	COG1309	transcriptional regulator
E6P06_RS14395	COG3313	Fe-S protein
E6P06_RS14400	COG4989	oxidoreductase activity
E6P06_RS14405	COG2032	superoxide dismutase activity
E6P06_RS14415	COG1566	PFAM secretion protein HlyD family protein
E6P06_RS14440	COG3895	Periplasmic Protein
E6P06_RS14455	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
E6P06_RS14460	COG0625	glutathione transferase activity
E6P06_RS14470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E6P06_RS14520	COG0673	inositol 2-dehydrogenase activity
E6P06_RS14530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E6P06_RS14535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS14535	COG1263	PTS System
E6P06_RS14585	COG3039	Transposase
E6P06_RS14625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E6P06_RS14630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS14630	COG1263	PTS System
E6P06_RS14635	COG1609	Transcriptional regulator
E6P06_RS14640	COG5339	Protein conserved in bacteria
E6P06_RS14650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS14650	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS14665	COG2205	protein histidine kinase activity
E6P06_RS14680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E6P06_RS14690	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
E6P06_RS14695	COG1823	symporter activity
E6P06_RS14700	COG0745	RESPONSE REGULATOR receiver
E6P06_RS14705	COG3136	membrane protein required for alginate biosynthesis
E6P06_RS14715	COG0531	amino acid
E6P06_RS14725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
E6P06_RS14730	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
E6P06_RS14735	COG0628	permease
E6P06_RS14755	COG3591	Belongs to the peptidase S1B family
E6P06_RS14765	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
E6P06_RS14790	COG0745	RESPONSE REGULATOR receiver
E6P06_RS14795	COG2205	protein histidine kinase activity
E6P06_RS14805	COG2814	Major facilitator Superfamily
E6P06_RS14810	COG0583	DNA-binding transcription factor activity
E6P06_RS14815	COG1940	carbohydrate kinase activity
E6P06_RS14820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
E6P06_RS14830	COG3381	protein complex oligomerization
E6P06_RS14835	COG3302	dmso reductase anchor subunit
E6P06_RS14840	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS14860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6P06_RS14875	COG4948	Mandelate Racemase Muconate Lactonizing
E6P06_RS14880	COG1063	alcohol dehydrogenase
E6P06_RS14885	COG0477	Major facilitator Superfamily
E6P06_RS14890	COG0246	Mannitol dehydrogenase
E6P06_RS14900	COG1802	Transcriptional regulator
E6P06_RS14905	COG4221	oxidoreductase activity
E6P06_RS14915	COG0500	methyltransferase
E6P06_RS14920	COG3706	GGDEF domain
E6P06_RS14945	COG1129	ABC transporter
E6P06_RS14950	COG0410	ABC transporter
E6P06_RS14955	COG2814	Major facilitator Superfamily
E6P06_RS14960	COG0697	spore germination
E6P06_RS14975	COG1846	Transcriptional regulator
E6P06_RS14990	COG0583	DNA-binding transcription factor activity
E6P06_RS14995	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS15060	COG3781	membrane
E6P06_RS15090	COG3121	Chaperone
E6P06_RS15105	COG3121	Chaperone
E6P06_RS15130	COG4628	conserved protein (DUF2132)
E6P06_RS15135	COG1649	PFAM Uncharacterised BCR, COG1649
E6P06_RS15155	COG0840	transmembrane signaling receptor activity
E6P06_RS15170	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
E6P06_RS15175	COG0747	negative chemotaxis
E6P06_RS15180	COG0601	transmembrane transport
E6P06_RS15185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6P06_RS15190	COG0444	Belongs to the ABC transporter superfamily
E6P06_RS15195	COG4608	Belongs to the ABC transporter superfamily
E6P06_RS15205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E6P06_RS15210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E6P06_RS15220	COG1250	3-hydroxyacyl-CoA dehydrogenase
E6P06_RS15225	COG2610	gluconate transmembrane transporter activity
E6P06_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS15235	COG1764	response to oxidative stress
E6P06_RS15250	COG0488	(ABC) transporter
E6P06_RS15260	COG3093	addiction module antidote protein HigA
E6P06_RS15265	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
E6P06_RS15270	COG2864	formate dehydrogenase
E6P06_RS15275	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS15285	COG0697	spore germination
E6P06_RS15310	COG2223	nitrite transmembrane transporter activity
E6P06_RS15315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E6P06_RS15320	COG1140	nitrate reductase beta subunit
E6P06_RS15325	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E6P06_RS15330	COG2181	nitrate reductase activity
E6P06_RS15335	COG0384	phenazine biosynthesis protein PhzF
E6P06_RS15340	COG2162	N-hydroxyarylamine O-acetyltransferase activity
E6P06_RS15345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E6P06_RS15370	COG0625	glutathione transferase activity
E6P06_RS15375	COG0583	DNA-binding transcription factor activity
E6P06_RS15380	COG0604	alcohol dehydrogenase
E6P06_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS15380	COG3321	synthase
E6P06_RS15385	COG1126	abc transporter atp-binding protein
E6P06_RS15400	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E6P06_RS15405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E6P06_RS15410	COG1473	amidohydrolase
E6P06_RS15415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E6P06_RS15420	COG0840	transmembrane signaling receptor activity
E6P06_RS15440	COG2130	NADP-dependent
E6P06_RS15450	COG1247	-acetyltransferase
E6P06_RS15455	COG3238	Protein conserved in bacteria
E6P06_RS15465	COG0747	negative chemotaxis
E6P06_RS15495	COG2207	Transcriptional regulator
E6P06_RS15500	COG2814	Major facilitator Superfamily
E6P06_RS15510	COG1177	transmembrane transport
E6P06_RS15515	COG1176	ABC-type spermidine putrescine transport system, permease component I
E6P06_RS15520	COG3842	ATPase activity
E6P06_RS15525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E6P06_RS15530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6P06_RS15540	COG1271	oxidase subunit
E6P06_RS15545	COG1294	oxidase, subunit
E6P06_RS15560	COG0826	peptidase U32
E6P06_RS15565	COG1396	sequence-specific DNA binding
E6P06_RS15570	COG3135	benzoate transporter
E6P06_RS15580	COG0697	spore germination
E6P06_RS15590	COG0500	methyltransferase
E6P06_RS15595	COG1275	C4-dicarboxylate transporter malic acid transport protein
E6P06_RS15600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E6P06_RS15605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6P06_RS15615	COG2841	Protein conserved in bacteria
E6P06_RS15625	COG5383	Protein conserved in bacteria
E6P06_RS15630	COG1227	inorganic diphosphatase activity
E6P06_RS15635	COG0583	DNA-binding transcription factor activity
E6P06_RS15645	COG3121	Chaperone
E6P06_RS15650	COG3188	usher protein
E6P06_RS15670	COG0840	transmembrane signaling receptor activity
E6P06_RS15690	COG3059	membrane
E6P06_RS15700	COG3383	formate dehydrogenase (NAD+) activity
E6P06_RS15700	COG0243	molybdopterin cofactor binding
E6P06_RS15705	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS15710	COG2864	formate dehydrogenase
E6P06_RS15715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E6P06_RS15725	COG3038	cytochrome b561
E6P06_RS15730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E6P06_RS15735	COG2755	lipolytic protein G-D-S-L family
E6P06_RS15735	COG0657	acetylesterase activity
E6P06_RS15740	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS15745	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E6P06_RS15750	COG1643	Atp-dependent helicase
E6P06_RS15765	COG3784	Protein of unknown function (DUF1318)
E6P06_RS15775	COG2911	Protein conserved in bacteria
E6P06_RS15785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E6P06_RS15790	COG3187	Heat shock protein
E6P06_RS15795	COG3042	response to heat
E6P06_RS15800	COG1013	pyruvate-flavodoxin oxidoreductase activity
E6P06_RS15800	COG0674	pyruvate-flavodoxin oxidoreductase activity
E6P06_RS15800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E6P06_RS15800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6P06_RS15805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E6P06_RS15815	COG0589	response to stress
E6P06_RS15825	COG0513	Belongs to the DEAD box helicase family
E6P06_RS15835	COG0840	transmembrane signaling receptor activity
E6P06_RS15855	COG3706	GGDEF domain
E6P06_RS15860	COG2840	Smr protein MutS2
E6P06_RS15865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E6P06_RS15880	COG3182	Iron-regulated membrane protein
E6P06_RS15885	COG0668	transmembrane transport
E6P06_RS15890	COG1064	alcohol dehydrogenase
E6P06_RS15895	COG0346	lactoylglutathione lyase activity
E6P06_RS15900	COG1349	DNA-binding transcription factor activity
E6P06_RS15920	COG4166	transmembrane transport
E6P06_RS15925	COG2866	Carboxypeptidase
E6P06_RS15930	COG4948	Mandelate Racemase Muconate Lactonizing
E6P06_RS15935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E6P06_RS15950	COG3106	COG3106 Predicted ATPase
E6P06_RS15955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E6P06_RS15960	COG1609	Transcriptional regulator
E6P06_RS15970	COG3842	ATPase activity
E6P06_RS15975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6P06_RS15980	COG1554	hydrolase, family 65, central catalytic
E6P06_RS15985	COG0673	inositol 2-dehydrogenase activity
E6P06_RS15990	COG1082	Xylose isomerase domain protein TIM barrel
E6P06_RS15995	COG1063	alcohol dehydrogenase
E6P06_RS16000	COG0395	ABC-type sugar transport system, permease component
E6P06_RS16005	COG1175	transmembrane transport
E6P06_RS16010	COG1653	transport
E6P06_RS16015	COG0366	Alpha amylase catalytic
E6P06_RS16025	COG1983	PspC domain protein
E6P06_RS16035	COG1842	Phage shock protein A
E6P06_RS16040	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E6P06_RS16065	COG4171	peptide transport system, permease
E6P06_RS16085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E6P06_RS16090	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6P06_RS16090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6P06_RS16100	COG5001	Diguanylate cyclase
E6P06_RS16115	COG1349	DNA-binding transcription factor activity
E6P06_RS16125	COG0023	Translation Initiation Factor
E6P06_RS16135	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
E6P06_RS16140	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
E6P06_RS16145	COG0671	phosphoesterase, PA-phosphatase related
E6P06_RS16155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E6P06_RS16165	COG0583	DNA-binding transcription factor activity
E6P06_RS16180	COG0616	signal peptide processing
E6P06_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS16195	COG1187	pseudouridine synthase activity
E6P06_RS16200	COG0009	L-threonylcarbamoyladenylate synthase
E6P06_RS16240	COG3706	GGDEF domain
E6P06_RS16255	COG0217	transcriptional regulatory protein
E6P06_RS16260	COG3047	cAMP biosynthetic process
E6P06_RS16285	COG2350	Protein conserved in bacteria
E6P06_RS16305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E6P06_RS16315	COG0444	Belongs to the ABC transporter superfamily
E6P06_RS16340	COG2095	MarC family integral membrane protein
E6P06_RS16345	COG1454	alcohol dehydrogenase
E6P06_RS16345	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS16350	COG1435	thymidine kinase activity
E6P06_RS16360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E6P06_RS16365	COG0745	RESPONSE REGULATOR receiver
E6P06_RS16370	COG1752	Esterase of the alpha-beta hydrolase superfamily
E6P06_RS16380	COG0788	formyltetrahydrofolate deformylase activity
E6P06_RS16410	COG2181	nitrate reductase activity
E6P06_RS16415	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E6P06_RS16420	COG1140	nitrate reductase beta subunit
E6P06_RS16425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E6P06_RS16430	COG2223	nitrite transmembrane transporter activity
E6P06_RS16435	COG3850	Histidine kinase
E6P06_RS16440	COG2197	response regulator
E6P06_RS16445	COG4932	domain protein
E6P06_RS16450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
E6P06_RS16460	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
E6P06_RS16465	COG0387	Pfam Sodium calcium exchanger
E6P06_RS16480	COG3094	Invasion gene expression up-regulator, SirB
E6P06_RS16485	COG2890	protein-(glutamine-N5) methyltransferase activity
E6P06_RS16515	COG0659	secondary active sulfate transmembrane transporter activity
E6P06_RS16520	COG0076	glutamate decarboxylase activity
E6P06_RS16525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E6P06_RS16530	COG0527	aspartate kinase activity
E6P06_RS16545	COG0012	GTP binding
E6P06_RS16605	COG2200	EAL domain
E6P06_RS16610	COG0789	Transcriptional regulator
E6P06_RS16635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E6P06_RS16640	COG2376	Dihydroxyacetone kinase
E6P06_RS16645	COG1461	Dihydroxyacetone kinase
E6P06_RS16660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E6P06_RS16665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E6P06_RS16670	COG1120	ATPase activity
E6P06_RS16675	COG0500	methyltransferase
E6P06_RS16680	COG0157	Belongs to the NadC ModD family
E6P06_RS16705	COG1619	proteins homologs of microcin C7 resistance protein MccF
E6P06_RS16715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E6P06_RS16725	COG2719	SpoVR family
E6P06_RS16755	COG0179	Fumarylacetoacetate (FAA) hydrolase
E6P06_RS16770	COG2894	cell division
E6P06_RS16780	COG0583	DNA-binding transcription factor activity
E6P06_RS16785	COG0473	3-isopropylmalate dehydrogenase activity
E6P06_RS16790	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
E6P06_RS16795	COG0318	PFAM AMP-dependent synthetase and ligase
E6P06_RS16800	COG3065	identical protein binding
E6P06_RS16805	COG1214	PFAM Peptidase M22, glycoprotease
E6P06_RS16810	COG1199	ATP-dependent helicase activity
E6P06_RS16815	COG0251	oxidation-reduction process
E6P06_RS16835	COG1760	l-serine dehydratase
E6P06_RS16840	COG2200	EAL domain
E6P06_RS16845	COG1253	flavin adenine dinucleotide binding
E6P06_RS16850	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS16850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS16855	COG3715	PTS system
E6P06_RS16860	COG3716	PTS system mannose fructose sorbose family IID component
E6P06_RS16875	COG2226	methyltransferase
E6P06_RS16880	COG0768	penicillin binding
E6P06_RS16910	COG1414	Transcriptional regulator
E6P06_RS16915	COG2814	Major facilitator Superfamily
E6P06_RS16930	COG2197	response regulator
E6P06_RS16960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E6P06_RS17020	COG1956	GAF domain-containing protein
E6P06_RS17025	COG2995	paraquat-inducible protein a
E6P06_RS17030	COG3008	intermembrane lipid transfer
E6P06_RS17050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E6P06_RS17060	COG1276	copper resistance
E6P06_RS17065	COG2372	response to copper ion
E6P06_RS17090	COG3706	GGDEF domain
E6P06_RS17115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E6P06_RS17120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E6P06_RS17125	COG1770	oligopeptidase
E6P06_RS17130	COG2979	Protein of unknown function (DUF533)
E6P06_RS17140	COG3141	response to X-ray
E6P06_RS17150	COG0800	Aldolase
E6P06_RS17155	COG0129	dihydroxy-acid dehydratase activity
E6P06_RS17160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E6P06_RS17165	COG1737	Transcriptional regulator
E6P06_RS17175	COG1560	Kdo2-lipid A biosynthetic process
E6P06_RS17180	COG0739	heme binding
E6P06_RS17185	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
E6P06_RS17195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E6P06_RS17220	COG0494	nUDIX hydrolase
E6P06_RS17235	COG1335	isochorismatase
E6P06_RS17285	COG4386	tail sheath protein
E6P06_RS17335	COG4626	Terminase
E6P06_RS17335	COG1802	Transcriptional regulator
E6P06_RS17375	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
E6P06_RS17410	COG0582	viral genome integration into host DNA
E6P06_RS17415	COG1801	Protein of unknown function DUF72
E6P06_RS17420	COG3788	relative of glutathione S-transferase, MAPEG superfamily
E6P06_RS17440	COG3102	Protein conserved in bacteria
E6P06_RS17455	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E6P06_RS17480	COG0745	RESPONSE REGULATOR receiver
E6P06_RS17495	COG0840	transmembrane signaling receptor activity
E6P06_RS17505	COG1301	dicarboxylic acid transport
E6P06_RS17515	COG0835	chemotaxis
E6P06_RS17550	COG0589	response to stress
E6P06_RS17565	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS17570	COG1129	ABC transporter
E6P06_RS17575	COG1879	ABC-type sugar transport system periplasmic component
E6P06_RS17585	COG1528	Iron-storage protein
E6P06_RS17595	COG0477	Major facilitator Superfamily
E6P06_RS17610	COG1528	Iron-storage protein
E6P06_RS17620	COG0814	amino acid
E6P06_RS17625	COG3318	Belongs to the UPF0149 family
E6P06_RS17625	COG3012	SEC-C Motif Domain Protein
E6P06_RS17630	COG2608	mercury ion transmembrane transporter activity
E6P06_RS17640	COG1305	Transglutaminase-like
E6P06_RS17645	COG3621	Patatin-like phospholipase
E6P06_RS17690	COG2197	response regulator
E6P06_RS17700	COG2197	response regulator
E6P06_RS17705	COG1126	abc transporter atp-binding protein
E6P06_RS17710	COG0765	amino acid transport
E6P06_RS17720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS17755	COG0366	Alpha amylase catalytic
E6P06_RS17770	COG0425	Belongs to the sulfur carrier protein TusA family
E6P06_RS17795	COG1157	protein secretion by the type III secretion system
E6P06_RS17800	COG2882	bacterial-type flagellum organization
E6P06_RS17860	COG5475	Uncharacterized small protein (DUF2158)
E6P06_RS17865	COG2354	Protein conserved in bacteria
E6P06_RS17870	COG0697	spore germination
E6P06_RS17875	COG3727	T/G mismatch-specific endonuclease activity
E6P06_RS17880	COG0270	DNA (cytosine-5-)-methyltransferase activity
E6P06_RS17885	COG1418	mRNA catabolic process
E6P06_RS17890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E6P06_RS17895	COG2076	Multidrug Resistance protein
E6P06_RS17920	COG1840	ABC-type Fe3 transport system, periplasmic component
E6P06_RS17925	COG1178	ABC-type Fe3 transport system permease component
E6P06_RS17930	COG3842	ATPase activity
E6P06_RS17935	COG1376	ErfK ybiS ycfS ynhG family protein
E6P06_RS18105	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
E6P06_RS18115	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS18125	COG4656	Part of a membrane complex involved in electron transport
E6P06_RS18160	COG1289	transmembrane transporter activity
E6P06_RS18190	COG2925	Exonuclease
E6P06_RS18195	COG0531	amino acid
E6P06_RS18205	COG0583	DNA-binding transcription factor activity
E6P06_RS18210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6P06_RS18240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E6P06_RS18255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
E6P06_RS18255	COG0140	phosphoribosyl-ATP diphosphatase activity
E6P06_RS18260	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
E6P06_RS18280	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E6P06_RS18285	COG0438	transferase activity, transferring glycosyl groups
E6P06_RS18290	COG3306	glycosyltransferase involved in LPS biosynthesis
E6P06_RS18325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E6P06_RS18345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6P06_RS18360	COG2327	Polysaccharide pyruvyl transferase
E6P06_RS18365	COG2244	polysaccharide biosynthetic process
E6P06_RS18370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E6P06_RS18375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E6P06_RS18385	COG0297	glycogen (starch) synthase activity
E6P06_RS18390	COG1051	belongs to the nudix hydrolase family
E6P06_RS18395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6P06_RS18400	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E6P06_RS18405	COG0110	maltose O-acetyltransferase activity
E6P06_RS18410	COG1216	Glycosyl transferase, family 2
E6P06_RS18420	COG0438	transferase activity, transferring glycosyl groups
E6P06_RS18425	COG1045	serine acetyltransferase
E6P06_RS18430	COG0463	Glycosyl transferase, family 2
E6P06_RS18435	COG3206	protein involved in exopolysaccharide biosynthesis
E6P06_RS18435	COG0489	protein tyrosine kinase activity
E6P06_RS18450	COG1253	flavin adenine dinucleotide binding
E6P06_RS18455	COG2982	Protein involved in outer membrane biogenesis
E6P06_RS18470	COG3447	MASE1 domain protein
E6P06_RS18470	COG5002	protein histidine kinase activity
E6P06_RS18470	COG5001	Diguanylate cyclase
E6P06_RS18475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E6P06_RS18480	COG0443	Heat shock 70 kDa protein
E6P06_RS18510	COG2205	protein histidine kinase activity
E6P06_RS18515	COG0745	RESPONSE REGULATOR receiver
E6P06_RS18525	COG0826	peptidase U32
E6P06_RS18530	COG0542	response to heat
E6P06_RS18540	COG1278	Cold shock
E6P06_RS18550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS18555	COG2990	Protein conserved in bacteria
E6P06_RS18560	COG3593	DNA synthesis involved in DNA repair
E6P06_RS18570	COG2431	L-lysine efflux transmembrane transporter activity
E6P06_RS18580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6P06_RS18585	COG4529	Protein conserved in bacteria
E6P06_RS18595	COG0028	Belongs to the TPP enzyme family
E6P06_RS18600	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
E6P06_RS18605	COG0702	epimerase
E6P06_RS18610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E6P06_RS18615	COG3023	N-Acetylmuramoyl-L-alanine amidase
E6P06_RS18630	COG1126	abc transporter atp-binding protein
E6P06_RS18635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS18640	COG4215	(ABC) transporter
E6P06_RS18645	COG4160	amino acid transport
E6P06_RS18650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS18660	COG1830	Aldolase
E6P06_RS18670	COG2211	Major facilitator Superfamily
E6P06_RS18675	COG1397	ADP-ribosylglycohydrolase
E6P06_RS18680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS18685	COG2188	Transcriptional regulator
E6P06_RS18690	COG0351	phosphomethylpyrimidine kinase
E6P06_RS18750	COG5455	response to cobalt ion
E6P06_RS18760	COG3188	usher protein
E6P06_RS18765	COG3121	Chaperone
E6P06_RS18780	COG0489	protein tyrosine kinase activity
E6P06_RS18790	COG4808	Protein conserved in bacteria
E6P06_RS18795	COG4807	Protein conserved in bacteria
E6P06_RS18805	COG3275	phosphorelay sensor kinase activity
E6P06_RS18810	COG0789	Transcriptional regulator
E6P06_RS18820	COG1174	glycine betaine transport
E6P06_RS18825	COG1125	glycine betaine transport
E6P06_RS18830	COG1174	glycine betaine transport
E6P06_RS18835	COG1732	Glycine betaine
E6P06_RS18840	COG1472	Belongs to the glycosyl hydrolase 3 family
E6P06_RS18845	COG0277	FAD linked oxidase domain protein
E6P06_RS18850	COG1686	Belongs to the peptidase S11 family
E6P06_RS18860	COG0586	Pfam SNARE associated Golgi protein
E6P06_RS18880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E6P06_RS18885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6P06_RS18890	COG0625	glutathione transferase activity
E6P06_RS18905	COG2271	Major facilitator Superfamily
E6P06_RS18920	COG1346	cytolysis
E6P06_RS18930	COG2949	membrane
E6P06_RS18940	COG0493	'glutamate synthase
E6P06_RS18955	COG1129	ABC transporter
E6P06_RS18970	COG2311	Membrane
E6P06_RS18990	COG1760	l-serine dehydratase
E6P06_RS18995	COG0560	Phosphoserine phosphatase
E6P06_RS19000	COG2271	Major facilitator Superfamily
E6P06_RS19005	COG4771	TonB-dependent receptor
E6P06_RS19010	COG0833	amino acid
E6P06_RS19015	COG0583	DNA-binding transcription factor activity
E6P06_RS19020	COG2855	membrane
E6P06_RS19030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS19030	COG1522	sequence-specific DNA binding
E6P06_RS19035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E6P06_RS19040	COG2313	pseudouridylate synthase activity
E6P06_RS19045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS19050	COG0583	DNA-binding transcription factor activity
E6P06_RS19060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E6P06_RS19065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS19065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS19065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
E6P06_RS19070	COG1105	Belongs to the carbohydrate kinase PfkB family
E6P06_RS19115	COG3381	protein complex oligomerization
E6P06_RS19125	COG3005	denitrification pathway
E6P06_RS19130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E6P06_RS19135	COG1312	Catalyzes the dehydration of D-mannonate
E6P06_RS19140	COG0246	Mannitol dehydrogenase
E6P06_RS19145	COG0523	cobalamin synthesis protein
E6P06_RS19150	COG0671	phosphoesterase, PA-phosphatase related
E6P06_RS19155	COG0791	NLP P60 protein
E6P06_RS19160	COG2200	EAL domain
E6P06_RS19165	COG4166	transmembrane transport
E6P06_RS19170	COG4174	ABC transporter (Permease)
E6P06_RS19175	COG4239	(ABC) transporter, permease
E6P06_RS19180	COG4172	Belongs to the ABC transporter superfamily
E6P06_RS19195	COG2814	Major facilitator Superfamily
E6P06_RS19200	COG1187	pseudouridine synthase activity
E6P06_RS19205	COG1061	Type III restriction enzyme res subunit
E6P06_RS19275	COG0659	secondary active sulfate transmembrane transporter activity
E6P06_RS19280	COG2239	Acts as a magnesium transporter
E6P06_RS19285	COG4615	Cyclic peptide transporter
E6P06_RS19290	COG3145	DNA-N1-methyladenine dioxygenase activity
E6P06_RS19295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E6P06_RS19295	COG2169	Transcriptional regulator
E6P06_RS19300	COG1477	protein flavinylation
E6P06_RS19310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
E6P06_RS19315	COG2198	Histidine kinase
E6P06_RS19315	COG0642	Histidine kinase
E6P06_RS19330	COG3852	Histidine kinase
E6P06_RS19335	COG2204	response regulator
E6P06_RS19340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E6P06_RS19345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E6P06_RS19350	COG2031	fatty acid transporter
E6P06_RS19355	COG0183	Belongs to the thiolase family
E6P06_RS19380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6P06_RS19385	COG0584	glycerophosphoryl diester phosphodiesterase
E6P06_RS19390	COG2271	Major facilitator Superfamily
E6P06_RS19395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E6P06_RS19405	COG0247	lactate metabolic process
E6P06_RS19410	COG5464	transposase or invertase
E6P06_RS19495	COG1169	isochorismate synthase
E6P06_RS19500	COG4575	ribosome binding
E6P06_RS19505	COG2153	protein acetylation
E6P06_RS19515	COG0835	chemotaxis
E6P06_RS19515	COG0784	Response regulator, receiver
E6P06_RS19525	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6P06_RS19530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E6P06_RS19540	COG0839	Belongs to the complex I subunit 6 family
E6P06_RS19565	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
E6P06_RS19585	COG3039	Transposase
E6P06_RS19590	COG0436	Aminotransferase
E6P06_RS19600	COG0471	metal ion transport
E6P06_RS19600	COG0490	domain, Protein
E6P06_RS19605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6P06_RS19630	COG1288	antiporter activity
E6P06_RS19640	COG0622	Phosphoesterase
E6P06_RS19645	COG0625	glutathione transferase activity
E6P06_RS19650	COG0625	glutathione transferase activity
E6P06_RS19655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E6P06_RS19660	COG1090	epimerase
E6P06_RS19665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6P06_RS19670	COG4598	ABC transporter
E6P06_RS19680	COG4215	(ABC) transporter
E6P06_RS19690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS19700	COG0163	prenyltransferase activity
E6P06_RS19705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E6P06_RS19710	COG1286	toxin biosynthetic process
E6P06_RS19715	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
E6P06_RS19720	COG0285	dihydrofolate synthase activity
E6P06_RS19730	COG0586	Pfam SNARE associated Golgi protein
E6P06_RS19740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E6P06_RS19760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E6P06_RS19775	COG3101	peptidyl-lysine hydroxylation
E6P06_RS19780	COG0730	response to heat
E6P06_RS19805	COG2062	phosphohistidine phosphatase, SixA
E6P06_RS19820	COG3691	Protein conserved in bacteria
E6P06_RS19825	COG2067	long-chain fatty acid transport protein
E6P06_RS19835	COG2116	formate transmembrane transporter activity
E6P06_RS19845	COG0582	viral genome integration into host DNA
E6P06_RS20035	COG0840	transmembrane signaling receptor activity
E6P06_RS20045	COG3065	identical protein binding
E6P06_RS20050	COG2771	luxR family
E6P06_RS20055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E6P06_RS20060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS20080	COG3247	response to pH
E6P06_RS20095	COG0004	ammonium transporteR
E6P06_RS20110	COG0804	urea catabolic process
E6P06_RS20125	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E6P06_RS20130	COG0829	nickel cation binding
E6P06_RS20135	COG4413	Urea transporter
E6P06_RS20140	COG1285	pathogenesis
E6P06_RS20145	COG2197	response regulator
E6P06_RS20150	COG1917	Cupin 2, conserved barrel domain protein
E6P06_RS20150	COG4977	sequence-specific DNA binding
E6P06_RS20155	COG3122	Protein conserved in bacteria
E6P06_RS20175	COG3961	Belongs to the TPP enzyme family
E6P06_RS20180	COG0667	Aldo Keto reductase
E6P06_RS20195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E6P06_RS20210	COG3415	Transposase
E6P06_RS20215	COG3415	Transposase
E6P06_RS20245	COG0583	DNA-binding transcription factor activity
E6P06_RS20250	COG2211	Major facilitator Superfamily
E6P06_RS20255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E6P06_RS20265	COG0583	DNA-binding transcription factor activity
E6P06_RS20270	COG0385	Bile acid
E6P06_RS20275	COG3530	Putative quorum-sensing-regulated virulence factor
E6P06_RS20340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
E6P06_RS20345	COG4208	sulfate ABC transporter
E6P06_RS20350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
E6P06_RS20365	COG2837	iron assimilation
E6P06_RS20385	COG0860	N-Acetylmuramoyl-L-alanine amidase
E6P06_RS20395	COG2207	Transcriptional regulator
E6P06_RS20400	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
E6P06_RS20460	COG4812	Cobalamin adenosyltransferase
E6P06_RS20465	COG4766	ethanolamine catabolic process
E6P06_RS20485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E6P06_RS20490	COG5342	invasion associated locus B
E6P06_RS20500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6P06_RS20500	COG0493	'glutamate synthase
E6P06_RS20505	COG3850	Histidine kinase
E6P06_RS20510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6P06_RS20520	COG1393	Belongs to the ArsC family
E6P06_RS20535	COG0400	carboxylic ester hydrolase activity
E6P06_RS20545	COG2321	neutral zinc metallopeptidase
E6P06_RS20555	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
E6P06_RS20565	COG2716	regulation of RNA biosynthetic process
E6P06_RS20570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E6P06_RS20575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E6P06_RS20580	COG0700	Nucleoside recognition
E6P06_RS20585	COG3366	ferrous iron transmembrane transporter activity
E6P06_RS20590	COG0628	permease
E6P06_RS20595	COG4783	chaperone-mediated protein folding
E6P06_RS20600	COG1393	Belongs to the ArsC family
E6P06_RS20610	COG2233	PERMEase
E6P06_RS20620	COG2723	6-phospho-beta-galactosidase activity
E6P06_RS20630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E6P06_RS20640	COG0248	Ppx GppA phosphatase
E6P06_RS20645	COG2200	EAL domain
E6P06_RS20655	COG0668	transmembrane transport
E6P06_RS20665	COG3179	chitinase
E6P06_RS20680	COG3274	enterobacterial common antigen metabolic process
E6P06_RS20805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E6P06_RS20855	COG0516	GMP reductase activity
E6P06_RS20855	COG0517	IMP dehydrogenase activity
E6P06_RS20880	COG1645	bacterial-type flagellum-dependent swarming motility
E6P06_RS20905	COG2976	Protein conserved in bacteria
E6P06_RS20935	COG4953	penicillin-binding protein 1C
E6P06_RS20940	COG2373	Large extracellular alpha-helical protein
E6P06_RS20945	COG2897	thiosulfate sulfurtransferase activity
E6P06_RS20960	COG2975	iron-sulfur cluster assembly
E6P06_RS20965	COG0633	Ferredoxin
E6P06_RS20990	COG0822	iron-sulfur transferase activity
E6P06_RS20995	COG1104	cysteine desulfurase activity
E6P06_RS21015	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
E6P06_RS21020	COG3683	transport system, periplasmic component
E6P06_RS21030	COG1129	ABC transporter
E6P06_RS21035	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS21045	COG1069	ribulokinase activity
E6P06_RS21050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E6P06_RS21050	COG0517	IMP dehydrogenase activity
E6P06_RS21055	COG3711	transcriptional antiterminator
E6P06_RS21060	COG2814	Major facilitator Superfamily
E6P06_RS21070	COG0477	Major facilitator Superfamily
E6P06_RS21070	COG2814	Major facilitator Superfamily
E6P06_RS21075	COG0457	Tetratricopeptide repeat
E6P06_RS21080	COG1940	carbohydrate kinase activity
E6P06_RS21085	COG0583	DNA-binding transcription factor activity
E6P06_RS21090	COG4638	Rieske (2fe-2S)
E6P06_RS21120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
E6P06_RS21120	COG1017	nitric oxide dioxygenase activity
E6P06_RS21125	COG0347	Belongs to the P(II) protein family
E6P06_RS21130	COG2204	response regulator
E6P06_RS21135	COG3170	Tfp pilus assembly protein FimV
E6P06_RS21140	COG2205	protein histidine kinase activity
E6P06_RS21160	COG0560	Phosphoserine phosphatase
E6P06_RS21165	COG1263	PTS System
E6P06_RS21165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS21170	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E6P06_RS21175	COG1737	Transcriptional regulator
E6P06_RS21180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6P06_RS21190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
E6P06_RS21210	COG0681	Belongs to the peptidase S26 family
E6P06_RS21220	COG3086	response to oxidative stress
E6P06_RS21225	COG3026	antisigma factor binding
E6P06_RS21230	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
E6P06_RS21235	COG1595	DNA-templated transcription, initiation
E6P06_RS21245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E6P06_RS21255	COG0513	Belongs to the DEAD box helicase family
E6P06_RS21280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6P06_RS21285	COG3118	belongs to the thioredoxin family
E6P06_RS21290	COG3148	PFAM DTW domain containing protein
E6P06_RS21300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E6P06_RS21305	COG5544	Lipoprotein
E6P06_RS21310	COG0477	Major facilitator Superfamily
E6P06_RS21335	COG0542	response to heat
E6P06_RS21350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
E6P06_RS21355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E6P06_RS21365	COG0077	Prephenate dehydratase
E6P06_RS21365	COG1605	Chorismate mutase
E6P06_RS21370	COG1605	Chorismate mutase
E6P06_RS21370	COG0287	Prephenate dehydrogenase
E6P06_RS21375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
E6P06_RS21390	COG2199	diguanylate cyclase activity
E6P06_RS21395	COG2885	chlorophyll binding
E6P06_RS21420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E6P06_RS21430	COG4137	Cytochrome C assembly protein
E6P06_RS21435	COG4536	flavin adenine dinucleotide binding
E6P06_RS21450	COG0497	DNA recombination
E6P06_RS21465	COG2867	negative regulation of translational initiation
E6P06_RS21490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS21545	COG0582	viral genome integration into host DNA
E6P06_RS21555	COG0582	viral genome integration into host DNA
E6P06_RS21565	COG1475	DNA binding
E6P06_RS21580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E6P06_RS21590	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E6P06_RS21700	COG3039	Transposase
E6P06_RS21705	COG1388	LysM domain
E6P06_RS21705	COG1470	cell adhesion involved in biofilm formation
E6P06_RS21715	COG3718	enzyme involved in inositol metabolism
E6P06_RS21725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS21750	COG0673	inositol 2-dehydrogenase activity
E6P06_RS21755	COG3962	Belongs to the TPP enzyme family
E6P06_RS21770	COG3065	identical protein binding
E6P06_RS21775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS21780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6P06_RS21800	COG2205	protein histidine kinase activity
E6P06_RS21800	COG2198	Histidine kinase
E6P06_RS21800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS21800	COG0784	Response regulator, receiver
E6P06_RS21820	COG2271	Major facilitator Superfamily
E6P06_RS21825	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
E6P06_RS21830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E6P06_RS21835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E6P06_RS21840	COG3829	transcription factor binding
E6P06_RS21875	COG0438	transferase activity, transferring glycosyl groups
E6P06_RS21875	COG0297	glycogen (starch) synthase activity
E6P06_RS21880	COG0438	transferase activity, transferring glycosyl groups
E6P06_RS21925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E6P06_RS21935	COG3121	Chaperone
E6P06_RS21940	COG3188	usher protein
E6P06_RS21975	COG2199	diguanylate cyclase activity
E6P06_RS22005	COG0579	oxidoreductase
E6P06_RS22010	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS22015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E6P06_RS22020	COG1113	amino acid transport
E6P06_RS22025	COG1802	Transcriptional regulator
E6P06_RS22030	COG1652	LysM domain
E6P06_RS22035	COG0401	homolog of Blt101
E6P06_RS22040	COG0640	Transcriptional regulator
E6P06_RS22045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E6P06_RS22075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E6P06_RS22105	COG4176	ABC-type proline glycine betaine transport system permease component
E6P06_RS22115	COG2814	Major facilitator Superfamily
E6P06_RS22120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
E6P06_RS22130	COG1846	Transcriptional regulator
E6P06_RS22135	COG1566	PFAM secretion protein HlyD family protein
E6P06_RS22140	COG2814	Major facilitator Superfamily
E6P06_RS22165	COG1238	metal cluster binding
E6P06_RS22170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6P06_RS22200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
E6P06_RS22220	COG1546	Belongs to the CinA family
E6P06_RS22225	COG2951	lytic endotransglycosylase activity
E6P06_RS22230	COG3730	PTS system glucitol sorbitol-specific
E6P06_RS22235	COG3732	PTS system glucitol sorbitol-specific
E6P06_RS22245	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS22250	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS22255	COG1349	DNA-binding transcription factor activity
E6P06_RS22260	COG0517	IMP dehydrogenase activity
E6P06_RS22260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
E6P06_RS22280	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
E6P06_RS22285	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6P06_RS22290	COG1609	Transcriptional regulator
E6P06_RS22295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS22295	COG1263	PTS System
E6P06_RS22300	COG2723	6-phospho-beta-galactosidase activity
E6P06_RS22310	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E6P06_RS22320	COG3260	NADH ubiquinone oxidoreductase 20
E6P06_RS22325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E6P06_RS22330	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
E6P06_RS22330	COG3261	NADH dehydrogenase
E6P06_RS22335	COG0650	Formate hydrogenlyase subunit 4
E6P06_RS22340	COG0651	ATP synthesis coupled electron transport
E6P06_RS22345	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6P06_RS22355	COG0375	protein maturation
E6P06_RS22360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E6P06_RS22365	COG0298	carbon dioxide binding
E6P06_RS22370	COG0409	Hydrogenase expression formation protein
E6P06_RS22375	COG0309	Hydrogenase expression formation protein (HypE)
E6P06_RS22395	COG3069	C4-dicarboxylate transmembrane transporter activity
E6P06_RS22400	COG1737	Transcriptional regulator
E6P06_RS22405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E6P06_RS22425	COG1121	(ABC) transporter
E6P06_RS22430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E6P06_RS22435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E6P06_RS22440	COG2200	EAL domain
E6P06_RS22475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
E6P06_RS22480	COG0163	prenyltransferase activity
E6P06_RS22495	COG1388	LysM domain
E6P06_RS22495	COG4942	peptidase
E6P06_RS22550	COG2234	aminopeptidase activity
E6P06_RS22575	COG0720	synthase
E6P06_RS22580	COG0602	queuosine metabolic process
E6P06_RS22585	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
E6P06_RS22590	COG2190	(PTS) system
E6P06_RS22590	COG1263	PTS System
E6P06_RS22590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS22595	COG1737	Transcriptional regulator
E6P06_RS22630	COG3956	TIGRFAM MazG family protein
E6P06_RS22635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E6P06_RS22645	COG2205	protein histidine kinase activity
E6P06_RS22645	COG3850	Histidine kinase
E6P06_RS22645	COG4999	Histidine kinase
E6P06_RS22645	COG3437	response regulator, receiver
E6P06_RS22650	COG1929	Belongs to the glycerate kinase type-1 family
E6P06_RS22660	COG2271	Major facilitator Superfamily
E6P06_RS22665	COG0716	FMN binding
E6P06_RS22670	COG0564	pseudouridine synthase activity
E6P06_RS22675	COG3098	single-species biofilm formation
E6P06_RS22690	COG1611	Belongs to the LOG family
E6P06_RS22695	COG0814	amino acid
E6P06_RS22700	COG1760	l-serine dehydratase
E6P06_RS22710	COG1454	alcohol dehydrogenase
E6P06_RS22715	COG0235	Class ii aldolase
E6P06_RS22725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
E6P06_RS22735	COG1172	Belongs to the binding-protein-dependent transport system permease family
E6P06_RS22740	COG1129	ABC transporter
E6P06_RS22750	COG1070	Carbohydrate kinase
E6P06_RS22760	COG1349	DNA-binding transcription factor activity
E6P06_RS22770	COG2363	Small membrane protein
E6P06_RS22775	COG0583	DNA-binding transcription factor activity
E6P06_RS22785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E6P06_RS22790	COG2166	iron-sulfur cluster assembly
E6P06_RS22795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E6P06_RS22800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
E6P06_RS22835	COG3188	usher protein
E6P06_RS22840	COG3121	Chaperone
E6P06_RS22865	COG0860	N-Acetylmuramoyl-L-alanine amidase
E6P06_RS22870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
E6P06_RS22870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E6P06_RS22875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E6P06_RS22880	COG1074	ATP-dependent DNA helicase activity
E6P06_RS22890	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
E6P06_RS22895	COG4967	type IV pilus modification protein PilV
E6P06_RS22905	COG4795	General secretion pathway protein
E6P06_RS22910	COG2165	general secretion pathway protein
E6P06_RS22940	COG0861	Integral membrane protein TerC family
E6P06_RS22950	COG0667	Aldo Keto reductase
E6P06_RS22975	COG1609	Transcriptional regulator
E6P06_RS22985	COG0583	DNA-binding transcription factor activity
E6P06_RS22990	COG1794	racemase activity, acting on amino acids and derivatives
E6P06_RS23000	COG2814	Major facilitator Superfamily
E6P06_RS23005	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS23015	COG0183	Belongs to the thiolase family
E6P06_RS23030	COG0814	amino acid
E6P06_RS23045	COG0402	S-adenosylhomocysteine deaminase activity
E6P06_RS23050	COG0549	Belongs to the carbamate kinase family
E6P06_RS23060	COG1304	FMN binding
E6P06_RS23065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E6P06_RS23075	COG0666	response to abiotic stimulus
E6P06_RS23080	COG0583	DNA-binding transcription factor activity
E6P06_RS23085	COG2388	GCN5-related N-acetyl-transferase
E6P06_RS23090	COG3592	Divergent 4Fe-4S mono-cluster
E6P06_RS23100	COG1215	transferase activity, transferring glycosyl groups
E6P06_RS23105	COG1649	PFAM Uncharacterised BCR, COG1649
E6P06_RS23105	COG0726	polysaccharide deacetylase
E6P06_RS23110	COG0457	Tetratricopeptide repeat
E6P06_RS23125	COG4942	peptidase
E6P06_RS23145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E6P06_RS23170	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
E6P06_RS23180	COG1272	protein, Hemolysin III
E6P06_RS23190	COG1737	Transcriptional regulator
E6P06_RS23195	COG2723	6-phospho-beta-galactosidase activity
E6P06_RS23200	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS23220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6P06_RS23225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E6P06_RS23230	COG0006	proline dipeptidase activity
E6P06_RS23250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E6P06_RS23255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E6P06_RS23270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E6P06_RS23270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E6P06_RS23275	COG1703	isobutyryl-CoA mutase activity
E6P06_RS23280	COG1024	Enoyl-CoA hydratase
E6P06_RS23285	COG0427	acetyl-CoA hydrolase
E6P06_RS23290	COG0583	DNA-binding transcription factor activity
E6P06_RS23295	COG2968	Membrane
E6P06_RS23300	COG1279	arginine transmembrane transporter activity
E6P06_RS23305	COG0668	transmembrane transport
E6P06_RS23310	COG0191	fructose-bisphosphate aldolase activity
E6P06_RS23340	COG1122	ATPase activity
E6P06_RS23350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E6P06_RS23360	COG0501	Belongs to the peptidase M48B family
E6P06_RS23370	COG1166	arginine decarboxylase activity
E6P06_RS23385	COG2814	Major facilitator Superfamily
E6P06_RS23390	COG3091	SprT-like family
E6P06_RS23395	COG2356	endonuclease I
E6P06_RS23400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E6P06_RS23405	COG0189	ligase activity
E6P06_RS23420	COG2805	Type II/IV secretion system protein
E6P06_RS23425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E6P06_RS23430	COG0762	integral membrane protein
E6P06_RS23445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E6P06_RS23450	COG0252	asparaginase activity
E6P06_RS23460	COG3171	Protein conserved in bacteria
E6P06_RS23470	COG1194	a g-specific adenine glycosylase
E6P06_RS23485	COG2211	Major facilitator Superfamily
E6P06_RS23490	COG1982	Orn Lys Arg decarboxylase major
E6P06_RS23495	COG1811	Na channel or pump
E6P06_RS23530	COG3039	Transposase
E6P06_RS23540	COG0366	Alpha amylase catalytic
E6P06_RS23545	COG2190	(PTS) system
E6P06_RS23545	COG1263	PTS System
E6P06_RS23545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS23575	COG0754	glutathionylspermidine amidase activity
E6P06_RS23580	COG0243	molybdopterin cofactor binding
E6P06_RS23585	COG0625	glutathione transferase activity
E6P06_RS23590	COG0298	carbon dioxide binding
E6P06_RS23600	COG1773	rubredoxin
E6P06_RS23605	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E6P06_RS23610	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
E6P06_RS23615	COG5557	Pfam Polysulphide reductase, NrfD
E6P06_RS23620	COG0437	4 iron, 4 sulfur cluster binding
E6P06_RS23625	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
E6P06_RS23635	COG0840	transmembrane signaling receptor activity
E6P06_RS23645	COG0667	Aldo Keto reductase
E6P06_RS23665	COG0848	biopolymer transport protein
E6P06_RS23675	COG0626	cystathionine gamma-synthase activity
E6P06_RS23680	COG0586	Pfam SNARE associated Golgi protein
E6P06_RS23685	COG2207	Transcriptional regulator
E6P06_RS23690	COG1979	alcohol dehydrogenase
E6P06_RS23695	COG0656	L-ascorbic acid biosynthetic process
E6P06_RS23700	COG0471	metal ion transport
E6P06_RS23715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E6P06_RS23735	COG3111	PFAM Bacterial OB fold (BOF) protein
E6P06_RS23750	COG2249	NAD(P)H dehydrogenase (quinone) activity
E6P06_RS23755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
E6P06_RS23760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E6P06_RS23765	COG2211	Major facilitator Superfamily
E6P06_RS23775	COG1917	Cupin 2, conserved barrel domain protein
E6P06_RS23775	COG4977	sequence-specific DNA binding
E6P06_RS23780	COG0187	DNA topoisomerase II activity
E6P06_RS23785	COG3150	esterase
E6P06_RS23790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E6P06_RS23800	COG0494	nUDIX hydrolase
E6P06_RS23815	COG0754	glutathionylspermidine amidase activity
E6P06_RS23820	COG3384	dioxygenase
E6P06_RS23860	COG1585	Membrane protein implicated in regulation of membrane protease activity
E6P06_RS23865	COG2268	Band 7 protein
E6P06_RS23880	COG3025	triphosphatase activity
E6P06_RS23885	COG4991	sh3 domain protein
E6P06_RS23900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E6P06_RS23915	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS23920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E6P06_RS23950	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
E6P06_RS23960	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
E6P06_RS23965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
E6P06_RS23970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E6P06_RS23975	COG0358	DNA primase activity
E6P06_RS23985	COG3391	amine dehydrogenase activity
E6P06_RS23990	COG4771	TonB-dependent receptor
E6P06_RS24070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
E6P06_RS24080	COG2375	cellular response to nickel ion
E6P06_RS24085	COG1695	Transcriptional regulator
E6P06_RS24090	COG0840	transmembrane signaling receptor activity
E6P06_RS24100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E6P06_RS24105	COG1609	Transcriptional regulator
E6P06_RS24110	COG3250	beta-galactosidase activity
E6P06_RS24115	COG2731	YhcH YjgK YiaL family protein
E6P06_RS24120	COG0531	amino acid
E6P06_RS24130	COG3408	Glycogen debranching enzyme
E6P06_RS24130	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
E6P06_RS24135	COG1902	pentaerythritol trinitrate reductase activity
E6P06_RS24135	COG0446	pyridine nucleotide-disulphide oxidoreductase
E6P06_RS24145	COG1451	nucleotide metabolic process
E6P06_RS24150	COG0673	inositol 2-dehydrogenase activity
E6P06_RS24170	COG2721	sulfolactate sulfo-lyase activity
E6P06_RS24180	COG2271	Major facilitator Superfamily
E6P06_RS24185	COG2186	Transcriptional regulator
E6P06_RS24190	COG0586	Pfam SNARE associated Golgi protein
E6P06_RS24200	COG1422	Protein of unknown function (DUF1090)
E6P06_RS24205	COG4575	ribosome binding
E6P06_RS24210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
E6P06_RS24220	COG2259	Doxx family
E6P06_RS24225	COG0435	Glutathione S-transferase
E6P06_RS24235	COG3152	Membrane
E6P06_RS24240	COG0583	DNA-binding transcription factor activity
E6P06_RS24245	COG1741	Belongs to the pirin family
E6P06_RS24260	COG0814	amino acid
E6P06_RS24265	COG1760	l-serine dehydratase
E6P06_RS24270	COG0251	oxidation-reduction process
E6P06_RS24275	COG1882	Formate acetyltransferase
E6P06_RS24295	COG0583	DNA-binding transcription factor activity
E6P06_RS24305	COG1929	Belongs to the glycerate kinase type-1 family
E6P06_RS24310	COG2084	Dehydrogenase
E6P06_RS24320	COG2271	Major facilitator Superfamily
E6P06_RS24330	COG2721	sulfolactate sulfo-lyase activity
E6P06_RS24340	COG1175	transmembrane transport
E6P06_RS24345	COG0395	ABC-type sugar transport system, permease component
E6P06_RS24350	COG3842	ATPase activity
E6P06_RS24355	COG0673	inositol 2-dehydrogenase activity
E6P06_RS24360	COG1940	carbohydrate kinase activity
E6P06_RS24365	COG1349	DNA-binding transcription factor activity
E6P06_RS24370	COG1349	DNA-binding transcription factor activity
E6P06_RS24380	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS24390	COG3716	PTS system mannose fructose sorbose family IID component
E6P06_RS24395	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS24400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E6P06_RS24405	COG2222	sugar isomerase
E6P06_RS24415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS24420	COG3715	PTS system
E6P06_RS24425	COG3716	PTS system mannose fructose sorbose family IID component
E6P06_RS24430	COG0363	glucosamine-6-phosphate deaminase activity
E6P06_RS24440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E6P06_RS24460	COG2823	Periplasmic or secreted lipoprotein
E6P06_RS24465	COG0702	epimerase
E6P06_RS24480	COG3153	acetyltransferase
E6P06_RS24485	COG3154	lipid carrier protein
E6P06_RS24490	COG0826	peptidase U32
E6P06_RS24495	COG0826	peptidase U32
E6P06_RS24500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E6P06_RS24505	COG0814	amino acid
E6P06_RS24510	COG0513	Belongs to the DEAD box helicase family
E6P06_RS24540	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E6P06_RS24550	COG0195	Participates in both transcription termination and antitermination
E6P06_RS24575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E6P06_RS24580	COG0583	DNA-binding transcription factor activity
E6P06_RS24585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E6P06_RS24590	COG3069	C4-dicarboxylate transmembrane transporter activity
E6P06_RS24600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E6P06_RS24605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E6P06_RS24615	COG1534	Rna-binding protein
E6P06_RS24630	COG2027	D-alanyl-D-alanine carboxypeptidase
E6P06_RS24640	COG0697	spore germination
E6P06_RS24645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E6P06_RS24650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E6P06_RS24655	COG0142	geranyltranstransferase activity
E6P06_RS24660	COG3423	Transcriptional regulator
E6P06_RS24670	COG5007	Belongs to the BolA IbaG family
E6P06_RS24675	COG3113	response to antibiotic
E6P06_RS24680	COG2854	intermembrane phospholipid transfer
E6P06_RS24685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
E6P06_RS24690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E6P06_RS24695	COG1127	ABC transporter
E6P06_RS24700	COG0530	calcium, potassium:sodium antiporter activity
E6P06_RS24710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E6P06_RS24715	COG3117	lipopolysaccharide transmembrane transporter activity
E6P06_RS24720	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
E6P06_RS24725	COG1137	ATPase activity
E6P06_RS24735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E6P06_RS24750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS24760	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
E6P06_RS24765	COG2198	Histidine kinase
E6P06_RS24765	COG0784	Response regulator, receiver
E6P06_RS24765	COG5002	protein histidine kinase activity
E6P06_RS24770	COG1242	4 iron, 4 sulfur cluster binding
E6P06_RS24775	COG0069	glutamate synthase activity
E6P06_RS24775	COG0067	glutamate synthase
E6P06_RS24775	COG0070	glutamate synthase
E6P06_RS24780	COG0493	'glutamate synthase
E6P06_RS24785	COG4804	nuclease activity
E6P06_RS24790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
E6P06_RS24795	COG0402	S-adenosylhomocysteine deaminase activity
E6P06_RS24800	COG2731	YhcH YjgK YiaL family protein
E6P06_RS24825	COG3069	C4-dicarboxylate transmembrane transporter activity
E6P06_RS24830	COG2969	positive regulation of protein catabolic process
E6P06_RS24835	COG0625	glutathione transferase activity
E6P06_RS24850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
E6P06_RS24855	COG3105	Protein conserved in bacteria
E6P06_RS24860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6P06_RS24865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E6P06_RS24890	COG2732	(Barnase) inhibitor
E6P06_RS24910	COG0583	DNA-binding transcription factor activity
E6P06_RS24915	COG0312	modulator of DNA gyrase
E6P06_RS24920	COG3164	Protein of unknown function
E6P06_RS24935	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
E6P06_RS24940	COG1792	Involved in formation and maintenance of cell shape
E6P06_RS24945	COG1077	Cell shape determining protein MreB Mrl
E6P06_RS24950	COG2200	EAL domain
E6P06_RS24950	COG2199	diguanylate cyclase activity
E6P06_RS24955	COG0604	alcohol dehydrogenase
E6P06_RS24970	COG0511	ligase activity, forming carbon-carbon bonds
E6P06_RS24975	COG0439	Biotin carboxylase
E6P06_RS24980	COG3924	membrane
E6P06_RS24985	COG4145	pantothenate transmembrane transporter activity
E6P06_RS25015	COG1309	transcriptional regulator
E6P06_RS25020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS25025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E6P06_RS25035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E6P06_RS25040	COG4597	amino acid ABC transporter
E6P06_RS25045	COG0765	amino acid transport
E6P06_RS25050	COG1126	abc transporter atp-binding protein
E6P06_RS25090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E6P06_RS25100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E6P06_RS25110	COG0551	DNA topoisomerase type I activity
E6P06_RS25120	COG0758	DNA mediated transformation
E6P06_RS25140	COG0569	domain protein
E6P06_RS25150	COG3036	rescue of stalled ribosome
E6P06_RS25155	COG0789	Transcriptional regulator
E6P06_RS25180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E6P06_RS25195	COG0201	protein transport
E6P06_RS25200	COG0200	Binds to the 23S rRNA
E6P06_RS25275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E6P06_RS25290	COG0088	Forms part of the polypeptide exit tunnel
E6P06_RS25300	COG0051	transcription antitermination factor activity, RNA binding
E6P06_RS25330	COG0049	tRNA binding
E6P06_RS25355	COG2964	Protein conserved in bacteria
E6P06_RS25360	COG0545	Peptidyl-prolyl cis-trans isomerase
E6P06_RS25370	COG1047	Peptidyl-prolyl cis-trans
E6P06_RS25375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
E6P06_RS25390	COG0488	(ABC) transporter
E6P06_RS25400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E6P06_RS25410	COG0429	hydrolase of the alpha beta-hydrolase fold
E6P06_RS25420	COG3954	Phosphoribulokinase
E6P06_RS25425	COG1765	OsmC-like protein
E6P06_RS25435	COG1289	transmembrane transporter activity
E6P06_RS25440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E6P06_RS25445	COG0512	Glutamine amidotransferase of anthranilate synthase
E6P06_RS25470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E6P06_RS25475	COG2146	nitrite reductase [NAD(P)H] activity
E6P06_RS25500	COG0626	cystathionine gamma-synthase activity
E6P06_RS25515	COG1735	metal-dependent hydrolase with the TIM-barrel fold
E6P06_RS25520	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E6P06_RS25525	COG3457	Alanine racemase
E6P06_RS25535	COG2188	Transcriptional regulator
E6P06_RS25540	COG0180	Tryptophanyl-tRNA synthetase
E6P06_RS25550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E6P06_RS25555	COG0338	D12 class N6 adenine-specific DNA methyltransferase
E6P06_RS25560	COG3266	domain, Protein
E6P06_RS25575	COG4796	Type ii and iii secretion system protein
E6P06_RS25590	COG3166	PFAM Fimbrial assembly family protein
E6P06_RS25595	COG4972	Pilus assembly protein
E6P06_RS25600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E6P06_RS25605	COG0494	nUDIX hydrolase
E6P06_RS25615	COG1011	Hydrolase
E6P06_RS25620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E6P06_RS25630	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
E6P06_RS25660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E6P06_RS25665	COG2183	response to ionizing radiation
E6P06_RS25670	COG1918	ferrous iron import across plasma membrane
E6P06_RS25685	COG5464	transposase or invertase
E6P06_RS25695	COG1040	competence protein
E6P06_RS25705	COG2610	gluconate transmembrane transporter activity
E6P06_RS25710	COG1640	4-alpha-glucanotransferase
E6P06_RS25715	COG0058	SHG alpha-glucan phosphorylase activity
E6P06_RS25725	COG1349	DNA-binding transcription factor activity
E6P06_RS25740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E6P06_RS25745	COG0058	SHG alpha-glucan phosphorylase activity
E6P06_RS25770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E6P06_RS25775	COG2095	MarC family integral membrane protein
E6P06_RS25795	COG2610	gluconate transmembrane transporter activity
E6P06_RS25800	COG3265	gluconokinase activity
E6P06_RS25805	COG1609	Transcriptional regulator
E6P06_RS25810	COG1741	Belongs to the pirin family
E6P06_RS25815	COG0673	inositol 2-dehydrogenase activity
E6P06_RS25820	COG1247	-acetyltransferase
E6P06_RS25840	COG3157	Type VI secretion system effector, Hcp
E6P06_RS25850	COG0405	Gamma-glutamyltransferase
E6P06_RS25860	COG0584	glycerophosphoryl diester phosphodiesterase
E6P06_RS25895	COG0411	ABC transporter
E6P06_RS25900	COG4177	L-phenylalanine transmembrane transporter activity
E6P06_RS25910	COG0683	leucine binding
E6P06_RS25930	COG2177	Part of the ABC transporter FtsEX involved in
E6P06_RS25935	COG2884	Cell division ATP-binding protein ftsE
E6P06_RS25940	COG0552	protein localization to endoplasmic reticulum
E6P06_RS25945	COG0742	ribosomal rna small subunit methyltransferase
E6P06_RS25950	COG3776	membrane
E6P06_RS25975	COG3714	YhhN family
E6P06_RS25990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
E6P06_RS26000	COG0477	Major facilitator Superfamily
E6P06_RS26005	COG0628	permease
E6P06_RS26010	COG2091	lysine biosynthetic process via aminoadipic acid
E6P06_RS26030	COG0842	Transport permease protein
E6P06_RS26035	COG1129	ABC transporter
E6P06_RS26035	COG0842	Transport permease protein
E6P06_RS26040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS26045	COG2239	Acts as a magnesium transporter
E6P06_RS26055	COG2205	protein histidine kinase activity
E6P06_RS26060	COG0745	RESPONSE REGULATOR receiver
E6P06_RS26065	COG1276	copper resistance
E6P06_RS26070	COG2372	response to copper ion
E6P06_RS26075	COG3667	copper resistance
E6P06_RS26080	COG2132	Multicopper oxidase
E6P06_RS26090	COG0739	heme binding
E6P06_RS26120	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E6P06_RS26195	COG2081	HI0933 family
E6P06_RS26200	COG0306	phosphate transporter
E6P06_RS26210	COG0589	response to stress
E6P06_RS26220	COG1959	2 iron, 2 sulfur cluster binding
E6P06_RS26235	COG0339	signal peptide processing
E6P06_RS26240	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
E6P06_RS26245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E6P06_RS26255	COG1858	cytochrome C peroxidase
E6P06_RS26270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E6P06_RS26280	COG2197	response regulator
E6P06_RS26285	COG2200	EAL domain
E6P06_RS26295	COG1028	Short-chain dehydrogenase reductase Sdr
E6P06_RS26300	COG0583	DNA-binding transcription factor activity
E6P06_RS26305	COG1295	ribonuclease BN
E6P06_RS26310	COG0477	Major facilitator Superfamily
E6P06_RS26315	COG2982	Protein involved in outer membrane biogenesis
E6P06_RS26320	COG2200	EAL domain
E6P06_RS26325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS26340	COG2199	diguanylate cyclase activity
E6P06_RS26340	COG2200	EAL domain
E6P06_RS26350	COG0626	cystathionine gamma-synthase activity
E6P06_RS26355	COG0814	amino acid
E6P06_RS26360	COG2204	response regulator
E6P06_RS26365	COG4608	Belongs to the ABC transporter superfamily
E6P06_RS26370	COG0444	Belongs to the ABC transporter superfamily
E6P06_RS26375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E6P06_RS26380	COG0601	transmembrane transport
E6P06_RS26390	COG0747	negative chemotaxis
E6P06_RS26430	COG2223	nitrite transmembrane transporter activity
E6P06_RS26435	COG5571	outer membrane autotransporter
E6P06_RS26440	COG2818	Glycosylase
E6P06_RS26445	COG0456	acetyltransferase
E6P06_RS26450	COG0243	molybdopterin cofactor binding
E6P06_RS26455	COG2885	chlorophyll binding
E6P06_RS26460	COG1609	Transcriptional regulator
E6P06_RS26470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E6P06_RS26495	COG2944	sequence-specific DNA binding
E6P06_RS26500	COG1278	Cold shock
E6P06_RS26525	COG3274	enterobacterial common antigen metabolic process
E6P06_RS26530	COG4682	membrane
E6P06_RS26535	COG1070	Carbohydrate kinase
E6P06_RS26545	COG2207	Transcriptional regulator
E6P06_RS26545	COG1609	Transcriptional regulator
E6P06_RS26550	COG2992	FlgJ-related protein
E6P06_RS26555	COG0366	Alpha amylase catalytic
E6P06_RS26560	COG3977	Valine--pyruvate aminotransferase
E6P06_RS26565	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
E6P06_RS26570	COG1414	Transcriptional regulator
E6P06_RS26580	COG2731	YhcH YjgK YiaL family protein
E6P06_RS26590	COG2271	Major facilitator Superfamily
E6P06_RS26595	COG1070	Carbohydrate kinase
E6P06_RS26600	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
E6P06_RS26605	COG3623	hexulose-6-phosphate isomerase
E6P06_RS26610	COG0235	Class ii aldolase
E6P06_RS26615	COG4977	sequence-specific DNA binding
E6P06_RS26615	COG1917	Cupin 2, conserved barrel domain protein
E6P06_RS26620	COG2211	Major facilitator Superfamily
E6P06_RS26630	COG3713	MltA-interacting MipA family protein
E6P06_RS26635	COG0583	DNA-binding transcription factor activity
E6P06_RS26640	COG1566	PFAM secretion protein HlyD family protein
E6P06_RS26650	COG1012	belongs to the aldehyde dehydrogenase family
E6P06_RS26655	COG1454	alcohol dehydrogenase
E6P06_RS26660	COG3276	selenocysteine insertion sequence binding
E6P06_RS26670	COG0625	glutathione transferase activity
E6P06_RS26675	COG1566	PFAM secretion protein HlyD family protein
E6P06_RS26690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS26690	COG2213	PTS system mannitol-specific
E6P06_RS26700	COG3722	fumarate hydratase activity
E6P06_RS26720	COG2186	Transcriptional regulator
E6P06_RS26730	COG2271	Major facilitator Superfamily
E6P06_RS26735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E6P06_RS26740	COG1045	serine acetyltransferase
E6P06_RS26755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
E6P06_RS26760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E6P06_RS26770	COG4942	peptidase
E6P06_RS26775	COG2861	carbohydrate metabolic process
E6P06_RS26780	COG1216	Glycosyl transferase, family 2
E6P06_RS26790	COG0156	8-amino-7-oxononanoate synthase activity
E6P06_RS26800	COG0859	PFAM glycosyl transferase family 9
E6P06_RS26810	COG3307	-O-antigen
E6P06_RS26815	COG3306	glycosyltransferase involved in LPS biosynthesis
E6P06_RS26820	COG1442	glycosyl transferase family 8
E6P06_RS26835	COG0515	serine threonine protein kinase
E6P06_RS26840	COG0438	transferase activity, transferring glycosyl groups
E6P06_RS26845	COG0859	PFAM glycosyl transferase family 9
E6P06_RS26850	COG1519	Transferase
E6P06_RS26865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E6P06_RS26880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E6P06_RS26905	COG1561	YicC-like family, N-terminal region
E6P06_RS26910	COG2860	membrane
E6P06_RS26930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E6P06_RS26935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E6P06_RS26940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E6P06_RS26945	COG0786	glutamate:sodium symporter activity
E6P06_RS26950	COG2233	PERMEase
E6P06_RS26955	COG2982	Protein involved in outer membrane biogenesis
E6P06_RS26965	COG0191	fructose-bisphosphate aldolase activity
E6P06_RS26975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS26975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS26980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS26985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS26985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E6P06_RS26985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS26990	COG3711	transcriptional antiterminator
E6P06_RS26995	COG1501	Belongs to the glycosyl hydrolase 31 family
E6P06_RS27000	COG2211	Major facilitator Superfamily
E6P06_RS27040	COG2771	luxR family
E6P06_RS27060	COG2197	response regulator
E6P06_RS27090	COG0583	DNA-binding transcription factor activity
E6P06_RS27095	COG0604	alcohol dehydrogenase
E6P06_RS27105	COG0697	spore germination
E6P06_RS27110	COG1464	Belongs to the NlpA lipoprotein family
E6P06_RS27115	COG5464	transposase or invertase
E6P06_RS27130	COG3716	PTS system mannose fructose sorbose family IID component
E6P06_RS27135	COG3715	PTS system
E6P06_RS27140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
E6P06_RS27140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E6P06_RS27165	COG2723	6-phospho-beta-galactosidase activity
E6P06_RS27175	COG3620	sequence-specific DNA binding
E6P06_RS27205	COG2197	response regulator
E6P06_RS27215	COG0738	Major facilitator superfamily
E6P06_RS27225	COG1349	DNA-binding transcription factor activity
E6P06_RS27230	COG0440	acetolactate synthase activity
E6P06_RS27235	COG0028	Belongs to the TPP enzyme family
E6P06_RS27255	COG2814	Major facilitator Superfamily
E6P06_RS27265	COG0583	DNA-binding transcription factor activity
E6P06_RS27270	COG2610	gluconate transmembrane transporter activity
E6P06_RS27280	COG0641	radical SAM
E6P06_RS27290	COG2149	membrane
E6P06_RS27295	COG3119	arylsulfatase activity
E6P06_RS27300	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E6P06_RS27305	COG2207	Transcriptional regulator
E6P06_RS27345	COG5645	(Lipo)protein
E6P06_RS27350	COG0823	Involved in the tonB-independent uptake of proteins
E6P06_RS27360	COG0561	phosphatase activity
E6P06_RS27375	COG0592	DNA-directed DNA polymerase activity
E6P06_RS27385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E6P06_RS27420	COG2091	lysine biosynthetic process via aminoadipic acid
E6P06_RS27425	COG0431	NADPH-dependent FMN reductase
E6P06_RS27430	COG2252	PERMEase
E6P06_RS27435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E6P06_RS27440	COG0704	Plays a role in the regulation of phosphate uptake
E6P06_RS27450	COG0581	inorganic phosphate transmembrane transporter activity
E6P06_RS27455	COG0573	inorganic phosphate transmembrane transporter activity
E6P06_RS27460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E6P06_RS27475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E6P06_RS27480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E6P06_RS27490	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit