locus-tag	class	description
HV191_RS00010	COG0592	DNA-directed DNA polymerase activity
HV191_RS00025	COG0561	phosphatase activity
HV191_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
HV191_RS00040	COG5645	(Lipo)protein
HV191_RS00065	COG2188	Transcriptional regulator
HV191_RS00080	COG2207	Transcriptional regulator
HV191_RS00085	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV191_RS00090	COG3119	arylsulfatase activity
HV191_RS00095	COG2149	membrane
HV191_RS00105	COG0641	radical SAM
HV191_RS00115	COG2610	gluconate transmembrane transporter activity
HV191_RS00120	COG0583	DNA-binding transcription factor activity
HV191_RS00135	COG2801	Transposase and inactivated derivatives
HV191_RS00145	COG2814	Major facilitator Superfamily
HV191_RS00165	COG0028	Belongs to the TPP enzyme family
HV191_RS00170	COG0440	acetolactate synthase activity
HV191_RS00175	COG1349	DNA-binding transcription factor activity
HV191_RS00185	COG0738	Major facilitator superfamily
HV191_RS00195	COG2197	response regulator
HV191_RS00215	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS00280	COG1136	(ABC) transporter
HV191_RS00290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HV191_RS00305	COG0582	viral genome integration into host DNA
HV191_RS00315	COG2211	Major facilitator Superfamily
HV191_RS00320	COG1501	Belongs to the glycosyl hydrolase 31 family
HV191_RS00340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS00340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS00340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS00345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS00350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS00350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS00360	COG0191	fructose-bisphosphate aldolase activity
HV191_RS00370	COG2982	Protein involved in outer membrane biogenesis
HV191_RS00375	COG2233	PERMEase
HV191_RS00380	COG0786	glutamate:sodium symporter activity
HV191_RS00385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV191_RS00390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV191_RS00395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV191_RS00415	COG2860	membrane
HV191_RS00490	COG1561	YicC-like family, N-terminal region
HV191_RS00515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV191_RS00530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV191_RS00545	COG1519	Transferase
HV191_RS00550	COG0859	PFAM glycosyl transferase family 9
HV191_RS00555	COG0438	transferase activity, transferring glycosyl groups
HV191_RS00560	COG0515	serine threonine protein kinase
HV191_RS00585	COG0859	PFAM glycosyl transferase family 9
HV191_RS00590	COG0859	PFAM glycosyl transferase family 9
HV191_RS00610	COG0156	8-amino-7-oxononanoate synthase activity
HV191_RS00625	COG1216	Glycosyl transferase, family 2
HV191_RS00630	COG2861	carbohydrate metabolic process
HV191_RS00635	COG4942	peptidase
HV191_RS00645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV191_RS00650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV191_RS00670	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV191_RS00675	COG2271	Major facilitator Superfamily
HV191_RS00685	COG2186	Transcriptional regulator
HV191_RS00705	COG3722	fumarate hydratase activity
HV191_RS00715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS00715	COG2213	PTS system mannitol-specific
HV191_RS00725	COG1566	PFAM secretion protein HlyD family protein
HV191_RS00730	COG0625	glutathione transferase activity
HV191_RS00740	COG3276	selenocysteine insertion sequence binding
HV191_RS00745	COG1454	alcohol dehydrogenase
HV191_RS00750	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS00760	COG1566	PFAM secretion protein HlyD family protein
HV191_RS00765	COG0583	DNA-binding transcription factor activity
HV191_RS00770	COG3713	MltA-interacting MipA family protein
HV191_RS00780	COG0235	Class ii aldolase
HV191_RS00785	COG3623	hexulose-6-phosphate isomerase
HV191_RS00790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HV191_RS00795	COG1070	Carbohydrate kinase
HV191_RS00800	COG2271	Major facilitator Superfamily
HV191_RS00810	COG2731	YhcH YjgK YiaL family protein
HV191_RS00820	COG1414	Transcriptional regulator
HV191_RS00825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS00830	COG3977	Valine--pyruvate aminotransferase
HV191_RS00835	COG0366	Alpha amylase catalytic
HV191_RS00840	COG2992	FlgJ-related protein
HV191_RS00845	COG1609	Transcriptional regulator
HV191_RS00845	COG2207	Transcriptional regulator
HV191_RS00850	COG4214	carbohydrate transport
HV191_RS00860	COG4213	ABC transporter substrate-binding protein
HV191_RS00870	COG1070	Carbohydrate kinase
HV191_RS00875	COG4682	membrane
HV191_RS00880	COG4682	membrane
HV191_RS00885	COG3274	enterobacterial common antigen metabolic process
HV191_RS00910	COG1278	Cold shock
HV191_RS00915	COG2944	sequence-specific DNA binding
HV191_RS00930	COG2814	Major facilitator Superfamily
HV191_RS00935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS00945	COG1609	Transcriptional regulator
HV191_RS00950	COG2885	chlorophyll binding
HV191_RS00955	COG0243	molybdopterin cofactor binding
HV191_RS00960	COG0456	acetyltransferase
HV191_RS00965	COG2818	Glycosylase
HV191_RS00970	COG5571	outer membrane autotransporter
HV191_RS00975	COG2223	nitrite transmembrane transporter activity
HV191_RS01000	COG0747	negative chemotaxis
HV191_RS01005	COG0601	transmembrane transport
HV191_RS01010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV191_RS01015	COG0444	Belongs to the ABC transporter superfamily
HV191_RS01020	COG4608	Belongs to the ABC transporter superfamily
HV191_RS01025	COG2204	response regulator
HV191_RS01030	COG0814	amino acid
HV191_RS01035	COG0626	cystathionine gamma-synthase activity
HV191_RS01045	COG2200	EAL domain
HV191_RS01045	COG2199	diguanylate cyclase activity
HV191_RS01060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS01065	COG2200	EAL domain
HV191_RS01070	COG2982	Protein involved in outer membrane biogenesis
HV191_RS01075	COG0477	Major facilitator Superfamily
HV191_RS01080	COG1295	ribonuclease BN
HV191_RS01085	COG0583	DNA-binding transcription factor activity
HV191_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS01095	COG2197	response regulator
HV191_RS01105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV191_RS01120	COG1858	cytochrome C peroxidase
HV191_RS01125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV191_RS01130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV191_RS01135	COG0339	signal peptide processing
HV191_RS01150	COG0246	Mannitol dehydrogenase
HV191_RS01155	COG1349	DNA-binding transcription factor activity
HV191_RS01165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS01165	COG2213	PTS system mannitol-specific
HV191_RS01180	COG1959	2 iron, 2 sulfur cluster binding
HV191_RS01190	COG0589	response to stress
HV191_RS01200	COG0306	phosphate transporter
HV191_RS01205	COG2081	HI0933 family
HV191_RS01225	COG5642	Protein of unknown function (DUF2384)
HV191_RS01240	COG3621	Patatin-like phospholipase
HV191_RS01285	COG2239	Acts as a magnesium transporter
HV191_RS01290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS01295	COG1129	ABC transporter
HV191_RS01295	COG0842	Transport permease protein
HV191_RS01300	COG0842	Transport permease protein
HV191_RS01315	COG3479	Phenolic acid decarboxylase
HV191_RS01320	COG2091	lysine biosynthetic process via aminoadipic acid
HV191_RS01325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV191_RS01330	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS01340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV191_RS01365	COG1216	Glycosyl transferase, family 2
HV191_RS01385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HV191_RS01415	COG0628	permease
HV191_RS01420	COG0477	Major facilitator Superfamily
HV191_RS01430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV191_RS01445	COG3714	YhhN family
HV191_RS01455	COG3776	membrane
HV191_RS01460	COG0742	ribosomal rna small subunit methyltransferase
HV191_RS01465	COG0552	protein localization to endoplasmic reticulum
HV191_RS01470	COG2884	Cell division ATP-binding protein ftsE
HV191_RS01475	COG2177	Part of the ABC transporter FtsEX involved in
HV191_RS01495	COG0683	leucine binding
HV191_RS01505	COG4177	L-phenylalanine transmembrane transporter activity
HV191_RS01510	COG0411	ABC transporter
HV191_RS01515	COG0410	ABC transporter
HV191_RS01545	COG0584	glycerophosphoryl diester phosphodiesterase
HV191_RS01555	COG0405	Gamma-glutamyltransferase
HV191_RS01565	COG1247	-acetyltransferase
HV191_RS01570	COG0673	inositol 2-dehydrogenase activity
HV191_RS01575	COG1741	Belongs to the pirin family
HV191_RS01580	COG1609	Transcriptional regulator
HV191_RS01585	COG3265	gluconokinase activity
HV191_RS01590	COG2610	gluconate transmembrane transporter activity
HV191_RS01600	COG2095	MarC family integral membrane protein
HV191_RS01605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV191_RS01630	COG0058	SHG alpha-glucan phosphorylase activity
HV191_RS01635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV191_RS01650	COG1349	DNA-binding transcription factor activity
HV191_RS01660	COG0058	SHG alpha-glucan phosphorylase activity
HV191_RS01665	COG1640	4-alpha-glucanotransferase
HV191_RS01670	COG2610	gluconate transmembrane transporter activity
HV191_RS01680	COG1040	competence protein
HV191_RS01690	COG5464	transposase or invertase
HV191_RS01705	COG1918	ferrous iron import across plasma membrane
HV191_RS01710	COG2183	response to ionizing radiation
HV191_RS01715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV191_RS01720	COG0745	RESPONSE REGULATOR receiver
HV191_RS01735	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HV191_RS01745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV191_RS01750	COG1011	Hydrolase
HV191_RS01760	COG0494	nUDIX hydrolase
HV191_RS01765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV191_RS01770	COG4972	Pilus assembly protein
HV191_RS01790	COG4796	Type ii and iii secretion system protein
HV191_RS01805	COG3266	domain, Protein
HV191_RS01810	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV191_RS01815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV191_RS01825	COG0180	Tryptophanyl-tRNA synthetase
HV191_RS01845	COG2146	nitrite reductase [NAD(P)H] activity
HV191_RS01850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV191_RS01875	COG0512	Glutamine amidotransferase of anthranilate synthase
HV191_RS01880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV191_RS01885	COG1289	transmembrane transporter activity
HV191_RS01895	COG1765	OsmC-like protein
HV191_RS01900	COG3954	Phosphoribulokinase
HV191_RS01910	COG0429	hydrolase of the alpha beta-hydrolase fold
HV191_RS01915	COG0488	(ABC) transporter
HV191_RS01930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV191_RS01935	COG1047	Peptidyl-prolyl cis-trans
HV191_RS01945	COG0545	Peptidyl-prolyl cis-trans isomerase
HV191_RS01950	COG2964	Protein conserved in bacteria
HV191_RS02010	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HV191_RS02015	COG3156	type II secretion system protein K
HV191_RS02020	COG4795	General secretion pathway protein
HV191_RS02025	COG2165	general secretion pathway protein
HV191_RS02030	COG2165	general secretion pathway protein
HV191_RS02035	COG2165	general secretion pathway protein
HV191_RS02040	COG1459	type II secretion system
HV191_RS02045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV191_RS02050	COG1450	Type ii and iii secretion system protein
HV191_RS02070	COG0051	transcription antitermination factor activity, RNA binding
HV191_RS02080	COG0088	Forms part of the polypeptide exit tunnel
HV191_RS02095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV191_RS02170	COG0200	Binds to the 23S rRNA
HV191_RS02175	COG0201	protein transport
HV191_RS02190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV191_RS02215	COG0789	Transcriptional regulator
HV191_RS02220	COG3036	rescue of stalled ribosome
HV191_RS02230	COG0569	domain protein
HV191_RS02250	COG0758	DNA mediated transformation
HV191_RS02260	COG0551	DNA topoisomerase type I activity
HV191_RS02280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV191_RS02320	COG1126	abc transporter atp-binding protein
HV191_RS02325	COG0765	amino acid transport
HV191_RS02330	COG4597	amino acid ABC transporter
HV191_RS02335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV191_RS02345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV191_RS02350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS02370	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HV191_RS02375	COG0582	viral genome integration into host DNA
HV191_RS02390	COG3561	AntA/AntB antirepressor
HV191_RS02480	COG4626	Terminase
HV191_RS02480	COG1802	Transcriptional regulator
HV191_RS02505	COG4145	pantothenate transmembrane transporter activity
HV191_RS02510	COG3924	membrane
HV191_RS02515	COG0439	Biotin carboxylase
HV191_RS02520	COG0511	ligase activity, forming carbon-carbon bonds
HV191_RS02535	COG0604	alcohol dehydrogenase
HV191_RS02540	COG2199	diguanylate cyclase activity
HV191_RS02540	COG2200	EAL domain
HV191_RS02545	COG1077	Cell shape determining protein MreB Mrl
HV191_RS02550	COG1792	Involved in formation and maintenance of cell shape
HV191_RS02555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV191_RS02565	COG1530	ribonuclease E activity
HV191_RS02570	COG3164	Protein of unknown function
HV191_RS02575	COG0312	modulator of DNA gyrase
HV191_RS02580	COG0583	DNA-binding transcription factor activity
HV191_RS02600	COG2732	(Barnase) inhibitor
HV191_RS02620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV191_RS02625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV191_RS02630	COG3105	Protein conserved in bacteria
HV191_RS02635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV191_RS02650	COG0625	glutathione transferase activity
HV191_RS02655	COG2969	positive regulation of protein catabolic process
HV191_RS02660	COG3069	C4-dicarboxylate transmembrane transporter activity
HV191_RS02690	COG2731	YhcH YjgK YiaL family protein
HV191_RS02695	COG0402	S-adenosylhomocysteine deaminase activity
HV191_RS02700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV191_RS02705	COG0493	'glutamate synthase
HV191_RS02710	COG0070	glutamate synthase
HV191_RS02710	COG0069	glutamate synthase activity
HV191_RS02710	COG0067	glutamate synthase
HV191_RS02715	COG1242	4 iron, 4 sulfur cluster binding
HV191_RS02720	COG2198	Histidine kinase
HV191_RS02720	COG0784	Response regulator, receiver
HV191_RS02720	COG5002	protein histidine kinase activity
HV191_RS02725	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV191_RS02735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS02750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV191_RS02760	COG1137	ATPase activity
HV191_RS02765	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV191_RS02770	COG3117	lipopolysaccharide transmembrane transporter activity
HV191_RS02775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV191_RS02780	COG0517	IMP dehydrogenase activity
HV191_RS02780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV191_RS02785	COG0530	calcium, potassium:sodium antiporter activity
HV191_RS02790	COG1127	ABC transporter
HV191_RS02795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV191_RS02800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV191_RS02805	COG2854	intermembrane phospholipid transfer
HV191_RS02810	COG3113	response to antibiotic
HV191_RS02815	COG5007	Belongs to the BolA IbaG family
HV191_RS02825	COG3423	Transcriptional regulator
HV191_RS02830	COG0142	geranyltranstransferase activity
HV191_RS02835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HV191_RS02840	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HV191_RS02845	COG0697	spore germination
HV191_RS02855	COG2027	D-alanyl-D-alanine carboxypeptidase
HV191_RS02865	COG1534	Rna-binding protein
HV191_RS02875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV191_RS02880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV191_RS02890	COG3069	C4-dicarboxylate transmembrane transporter activity
HV191_RS02895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV191_RS02900	COG0583	DNA-binding transcription factor activity
HV191_RS02905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV191_RS02930	COG0195	Participates in both transcription termination and antitermination
HV191_RS02940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HV191_RS02970	COG0513	Belongs to the DEAD box helicase family
HV191_RS02975	COG0814	amino acid
HV191_RS02980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV191_RS02985	COG0826	peptidase U32
HV191_RS02990	COG0826	peptidase U32
HV191_RS02995	COG3154	lipid carrier protein
HV191_RS03000	COG3153	acetyltransferase
HV191_RS03015	COG0702	epimerase
HV191_RS03020	COG2823	Periplasmic or secreted lipoprotein
HV191_RS03035	COG3107	peptidoglycan biosynthetic process
HV191_RS03040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV191_RS03055	COG1063	alcohol dehydrogenase
HV191_RS03060	COG3775	system Galactitol-specific IIC component
HV191_RS03065	COG3414	Phosphotransferase system galactitol-specific IIB component
HV191_RS03070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS03085	COG2721	sulfolactate sulfo-lyase activity
HV191_RS03090	COG2271	Major facilitator Superfamily
HV191_RS03100	COG2084	Dehydrogenase
HV191_RS03105	COG1929	Belongs to the glycerate kinase type-1 family
HV191_RS03115	COG0583	DNA-binding transcription factor activity
HV191_RS03135	COG1882	Formate acetyltransferase
HV191_RS03140	COG0251	oxidation-reduction process
HV191_RS03145	COG1760	l-serine dehydratase
HV191_RS03150	COG0814	amino acid
HV191_RS03165	COG1741	Belongs to the pirin family
HV191_RS03170	COG0583	DNA-binding transcription factor activity
HV191_RS03175	COG3152	Membrane
HV191_RS03180	COG0435	Glutathione S-transferase
HV191_RS03185	COG2259	Doxx family
HV191_RS03195	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV191_RS03200	COG4575	ribosome binding
HV191_RS03205	COG1422	Protein of unknown function (DUF1090)
HV191_RS03215	COG0586	Pfam SNARE associated Golgi protein
HV191_RS03220	COG2186	Transcriptional regulator
HV191_RS03225	COG2271	Major facilitator Superfamily
HV191_RS03235	COG2721	sulfolactate sulfo-lyase activity
HV191_RS03255	COG0673	inositol 2-dehydrogenase activity
HV191_RS03260	COG1451	nucleotide metabolic process
HV191_RS03270	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV191_RS03270	COG1902	pentaerythritol trinitrate reductase activity
HV191_RS03285	COG1609	Transcriptional regulator
HV191_RS03295	COG1175	transmembrane transport
HV191_RS03300	COG0395	ABC-type sugar transport system, permease component
HV191_RS03305	COG0366	Alpha amylase catalytic
HV191_RS03310	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HV191_RS03325	COG3250	beta-galactosidase activity
HV191_RS03330	COG1609	Transcriptional regulator
HV191_RS03335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV191_RS03345	COG0840	transmembrane signaling receptor activity
HV191_RS03350	COG1695	Transcriptional regulator
HV191_RS03355	COG2375	cellular response to nickel ion
HV191_RS03365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV191_RS03445	COG0358	DNA primase activity
HV191_RS03450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV191_RS03455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HV191_RS03460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV191_RS03470	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HV191_RS03500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS03505	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS03520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV191_RS03535	COG4991	sh3 domain protein
HV191_RS03540	COG3025	triphosphatase activity
HV191_RS03605	COG3384	dioxygenase
HV191_RS03610	COG0754	glutathionylspermidine amidase activity
HV191_RS03620	COG1538	Outer membrane efflux protein
HV191_RS03625	COG0494	nUDIX hydrolase
HV191_RS03630	COG3151	Protein conserved in bacteria
HV191_RS03635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV191_RS03640	COG3150	esterase
HV191_RS03645	COG0187	DNA topoisomerase II activity
HV191_RS03650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV191_RS03655	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV191_RS03670	COG3111	PFAM Bacterial OB fold (BOF) protein
HV191_RS03690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HV191_RS03705	COG0656	L-ascorbic acid biosynthetic process
HV191_RS03710	COG1979	alcohol dehydrogenase
HV191_RS03715	COG2207	Transcriptional regulator
HV191_RS03720	COG0586	Pfam SNARE associated Golgi protein
HV191_RS03725	COG0626	cystathionine gamma-synthase activity
HV191_RS03735	COG0848	biopolymer transport protein
HV191_RS03755	COG0667	Aldo Keto reductase
HV191_RS03765	COG0840	transmembrane signaling receptor activity
HV191_RS03775	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HV191_RS03780	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS03785	COG5557	Pfam Polysulphide reductase, NrfD
HV191_RS03790	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HV191_RS03795	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV191_RS03800	COG1773	rubredoxin
HV191_RS03810	COG0298	carbon dioxide binding
HV191_RS03815	COG0625	glutathione transferase activity
HV191_RS03820	COG0243	molybdopterin cofactor binding
HV191_RS03825	COG0754	glutathionylspermidine amidase activity
HV191_RS03850	COG2885	chlorophyll binding
HV191_RS03920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV191_RS03945	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS03960	COG0840	transmembrane signaling receptor activity
HV191_RS04045	COG0210	DNA helicase
HV191_RS04055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HV191_RS04065	COG1811	Na channel or pump
HV191_RS04070	COG1982	Orn Lys Arg decarboxylase major
HV191_RS04075	COG2211	Major facilitator Superfamily
HV191_RS04090	COG1194	a g-specific adenine glycosylase
HV191_RS04100	COG3171	Protein conserved in bacteria
HV191_RS04110	COG0252	asparaginase activity
HV191_RS04120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV191_RS04135	COG0762	integral membrane protein
HV191_RS04140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV191_RS04160	COG2805	Type II/IV secretion system protein
HV191_RS04175	COG0189	ligase activity
HV191_RS04180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV191_RS04185	COG2356	endonuclease I
HV191_RS04190	COG3091	SprT-like family
HV191_RS04195	COG2814	Major facilitator Superfamily
HV191_RS04215	COG1166	arginine decarboxylase activity
HV191_RS04225	COG0501	Belongs to the peptidase M48B family
HV191_RS04230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV191_RS04240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS04245	COG2213	PTS system mannitol-specific
HV191_RS04250	COG1063	alcohol dehydrogenase
HV191_RS04255	COG1494	fructose-1,6-bisphosphatase
HV191_RS04265	COG1072	(Pantothenic acid kinase))
HV191_RS04280	COG0191	fructose-bisphosphate aldolase activity
HV191_RS04285	COG0549	Belongs to the carbamate kinase family
HV191_RS04290	COG2271	Major facilitator Superfamily
HV191_RS04295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV191_RS04300	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV191_RS04310	COG0583	DNA-binding transcription factor activity
HV191_RS04315	COG0668	transmembrane transport
HV191_RS04325	COG1279	arginine transmembrane transporter activity
HV191_RS04330	COG2968	Membrane
HV191_RS04335	COG0583	DNA-binding transcription factor activity
HV191_RS04340	COG0427	acetyl-CoA hydrolase
HV191_RS04345	COG1024	Enoyl-CoA hydratase
HV191_RS04350	COG1703	isobutyryl-CoA mutase activity
HV191_RS04355	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV191_RS04355	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV191_RS04370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV191_RS04375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV191_RS04395	COG0006	proline dipeptidase activity
HV191_RS04400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV191_RS04405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV191_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS04430	COG2723	6-phospho-beta-galactosidase activity
HV191_RS04435	COG1737	Transcriptional regulator
HV191_RS04445	COG1272	protein, Hemolysin III
HV191_RS04455	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV191_RS04480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV191_RS04500	COG4942	peptidase
HV191_RS04515	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV191_RS04535	COG3039	Transposase
HV191_RS04545	COG1682	transport, permease protein
HV191_RS04550	COG1134	teichoic acid transport
HV191_RS04560	COG4783	chaperone-mediated protein folding
HV191_RS04560	COG1560	Kdo2-lipid A biosynthetic process
HV191_RS04570	COG0457	Tetratricopeptide repeat
HV191_RS04575	COG1649	PFAM Uncharacterised BCR, COG1649
HV191_RS04575	COG0726	polysaccharide deacetylase
HV191_RS04580	COG1215	transferase activity, transferring glycosyl groups
HV191_RS04590	COG3592	Divergent 4Fe-4S mono-cluster
HV191_RS04595	COG2388	GCN5-related N-acetyl-transferase
HV191_RS04600	COG0583	DNA-binding transcription factor activity
HV191_RS04605	COG0666	response to abiotic stimulus
HV191_RS04615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV191_RS04620	COG1304	FMN binding
HV191_RS04630	COG0549	Belongs to the carbamate kinase family
HV191_RS04635	COG0402	S-adenosylhomocysteine deaminase activity
HV191_RS04650	COG0814	amino acid
HV191_RS04665	COG0183	Belongs to the thiolase family
HV191_RS04675	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS04685	COG1794	racemase activity, acting on amino acids and derivatives
HV191_RS04690	COG0583	DNA-binding transcription factor activity
HV191_RS04700	COG1609	Transcriptional regulator
HV191_RS04720	COG0667	Aldo Keto reductase
HV191_RS04730	COG0861	Integral membrane protein TerC family
HV191_RS04760	COG2165	general secretion pathway protein
HV191_RS04765	COG4795	General secretion pathway protein
HV191_RS04775	COG4967	type IV pilus modification protein PilV
HV191_RS04780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV191_RS04790	COG1074	ATP-dependent DNA helicase activity
HV191_RS04795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV191_RS04800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV191_RS04800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV191_RS04805	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV191_RS04825	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV191_RS04830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV191_RS04835	COG2166	iron-sulfur cluster assembly
HV191_RS04840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV191_RS04850	COG0583	DNA-binding transcription factor activity
HV191_RS04855	COG2363	Small membrane protein
HV191_RS04865	COG1349	DNA-binding transcription factor activity
HV191_RS04875	COG1070	Carbohydrate kinase
HV191_RS04885	COG1129	ABC transporter
HV191_RS04890	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS04910	COG0235	Class ii aldolase
HV191_RS04915	COG1454	alcohol dehydrogenase
HV191_RS04920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HV191_RS04925	COG1760	l-serine dehydratase
HV191_RS04930	COG0814	amino acid
HV191_RS04935	COG1611	Belongs to the LOG family
HV191_RS04950	COG3098	single-species biofilm formation
HV191_RS04955	COG0564	pseudouridine synthase activity
HV191_RS04960	COG0716	FMN binding
HV191_RS04965	COG2271	Major facilitator Superfamily
HV191_RS04970	COG4948	Mandelate Racemase Muconate Lactonizing
HV191_RS04975	COG4948	Mandelate Racemase Muconate Lactonizing
HV191_RS04980	COG1929	Belongs to the glycerate kinase type-1 family
HV191_RS04985	COG3850	Histidine kinase
HV191_RS04985	COG3437	response regulator, receiver
HV191_RS04985	COG4999	Histidine kinase
HV191_RS04985	COG2205	protein histidine kinase activity
HV191_RS04995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV191_RS05000	COG3956	TIGRFAM MazG family protein
HV191_RS05015	COG1737	Transcriptional regulator
HV191_RS05020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS05020	COG1263	PTS System
HV191_RS05020	COG2190	(PTS) system
HV191_RS05025	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HV191_RS05030	COG0602	queuosine metabolic process
HV191_RS05035	COG1070	Carbohydrate kinase
HV191_RS05040	COG2223	nitrite transmembrane transporter activity
HV191_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS05050	COG0277	FAD linked oxidase domain protein
HV191_RS05055	COG0477	Major facilitator Superfamily
HV191_RS05060	COG2086	electron transfer activity
HV191_RS05065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HV191_RS05070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HV191_RS05075	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HV191_RS05080	COG0644	oxidoreductase
HV191_RS05085	COG0720	synthase
HV191_RS05105	COG1203	CRISPR-associated helicase, Cas3
HV191_RS05120	COG1857	crispr-associated protein
HV191_RS05135	COG1518	maintenance of DNA repeat elements
HV191_RS05140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV191_RS05145	COG2234	aminopeptidase activity
HV191_RS05200	COG1388	LysM domain
HV191_RS05200	COG4942	peptidase
HV191_RS05240	COG2200	EAL domain
HV191_RS05245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV191_RS05250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV191_RS05255	COG1121	(ABC) transporter
HV191_RS05275	COG0309	Hydrogenase expression formation protein (HypE)
HV191_RS05280	COG0409	Hydrogenase expression formation protein
HV191_RS05285	COG0298	carbon dioxide binding
HV191_RS05290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV191_RS05305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS05310	COG0651	ATP synthesis coupled electron transport
HV191_RS05315	COG0650	Formate hydrogenlyase subunit 4
HV191_RS05320	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV191_RS05320	COG3261	NADH dehydrogenase
HV191_RS05325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV191_RS05330	COG3260	NADH ubiquinone oxidoreductase 20
HV191_RS05340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV191_RS05355	COG2723	6-phospho-beta-galactosidase activity
HV191_RS05360	COG1263	PTS System
HV191_RS05360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS05365	COG1609	Transcriptional regulator
HV191_RS05370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS05375	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV191_RS05395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV191_RS05395	COG0517	IMP dehydrogenase activity
HV191_RS05400	COG1349	DNA-binding transcription factor activity
HV191_RS05405	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS05420	COG3732	PTS system glucitol sorbitol-specific
HV191_RS05425	COG3730	PTS system glucitol sorbitol-specific
HV191_RS05430	COG2951	lytic endotransglycosylase activity
HV191_RS05435	COG1546	Belongs to the CinA family
HV191_RS05455	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV191_RS05485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV191_RS05490	COG1238	metal cluster binding
HV191_RS05505	COG2814	Major facilitator Superfamily
HV191_RS05510	COG1566	PFAM secretion protein HlyD family protein
HV191_RS05515	COG1846	Transcriptional regulator
HV191_RS05525	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV191_RS05530	COG2814	Major facilitator Superfamily
HV191_RS05540	COG4176	ABC-type proline glycine betaine transport system permease component
HV191_RS05570	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV191_RS05600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV191_RS05605	COG0640	Transcriptional regulator
HV191_RS05610	COG0401	homolog of Blt101
HV191_RS05615	COG1652	LysM domain
HV191_RS05620	COG1802	Transcriptional regulator
HV191_RS05625	COG1113	amino acid transport
HV191_RS05630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV191_RS05635	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS05640	COG0579	oxidoreductase
HV191_RS05655	COG3039	Transposase
HV191_RS05680	COG0297	glycogen (starch) synthase activity
HV191_RS05680	COG0438	transferase activity, transferring glycosyl groups
HV191_RS05710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV191_RS05745	COG2378	regulation of single-species biofilm formation
HV191_RS05755	COG3596	GTP binding
HV191_RS05765	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS05775	COG3344	reverse transcriptase
HV191_RS05785	COG3039	Transposase
HV191_RS05790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV191_RS05840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV191_RS05850	COG0542	response to heat
HV191_RS05855	COG0071	Belongs to the small heat shock protein (HSP20) family
HV191_RS05885	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS05905	COG4983	Phage plasmid primase, P4 family domain protein
HV191_RS05910	COG3311	Transcriptional regulator
HV191_RS05920	COG0582	viral genome integration into host DNA
HV191_RS05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS05955	COG2867	negative regulation of translational initiation
HV191_RS05970	COG0497	DNA recombination
HV191_RS05985	COG4536	flavin adenine dinucleotide binding
HV191_RS05990	COG4137	Cytochrome C assembly protein
HV191_RS05995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV191_RS06020	COG2885	chlorophyll binding
HV191_RS06025	COG2199	diguanylate cyclase activity
HV191_RS06040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV191_RS06045	COG1605	Chorismate mutase
HV191_RS06045	COG0287	Prephenate dehydrogenase
HV191_RS06050	COG0077	Prephenate dehydratase
HV191_RS06050	COG1605	Chorismate mutase
HV191_RS06060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV191_RS06065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV191_RS06080	COG0542	response to heat
HV191_RS06110	COG0477	Major facilitator Superfamily
HV191_RS06115	COG5544	Lipoprotein
HV191_RS06120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV191_RS06135	COG3118	belongs to the thioredoxin family
HV191_RS06140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV191_RS06155	COG0513	Belongs to the DEAD box helicase family
HV191_RS06165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV191_RS06175	COG1595	DNA-templated transcription, initiation
HV191_RS06185	COG3026	antisigma factor binding
HV191_RS06190	COG3086	response to oxidative stress
HV191_RS06200	COG0681	Belongs to the peptidase S26 family
HV191_RS06220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV191_RS06230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS06235	COG1737	Transcriptional regulator
HV191_RS06240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV191_RS06245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS06245	COG1263	PTS System
HV191_RS06250	COG0560	Phosphoserine phosphatase
HV191_RS06270	COG2205	protein histidine kinase activity
HV191_RS06275	COG3170	Tfp pilus assembly protein FimV
HV191_RS06280	COG2204	response regulator
HV191_RS06285	COG0347	Belongs to the P(II) protein family
HV191_RS06290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV191_RS06290	COG1017	nitric oxide dioxygenase activity
HV191_RS06300	COG1940	carbohydrate kinase activity
HV191_RS06305	COG0457	Tetratricopeptide repeat
HV191_RS06310	COG1879	ABC-type sugar transport system periplasmic component
HV191_RS06315	COG1129	ABC transporter
HV191_RS06320	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS06325	COG1063	alcohol dehydrogenase
HV191_RS06330	COG2017	converts alpha-aldose to the beta-anomer
HV191_RS06355	COG4638	Rieske (2fe-2S)
HV191_RS06360	COG0583	DNA-binding transcription factor activity
HV191_RS06365	COG3539	Fimbrial protein
HV191_RS06370	COG3188	usher protein
HV191_RS06375	COG3121	Chaperone
HV191_RS06380	COG3539	Fimbrial protein
HV191_RS06385	COG2814	Major facilitator Superfamily
HV191_RS06390	COG3711	transcriptional antiterminator
HV191_RS06395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV191_RS06395	COG0517	IMP dehydrogenase activity
HV191_RS06400	COG1069	ribulokinase activity
HV191_RS06410	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS06415	COG1129	ABC transporter
HV191_RS06425	COG3683	transport system, periplasmic component
HV191_RS06430	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV191_RS06455	COG0822	iron-sulfur transferase activity
HV191_RS06475	COG0633	Ferredoxin
HV191_RS06480	COG2975	iron-sulfur cluster assembly
HV191_RS06495	COG2897	thiosulfate sulfurtransferase activity
HV191_RS06500	COG2373	Large extracellular alpha-helical protein
HV191_RS06505	COG4953	penicillin-binding protein 1C
HV191_RS06535	COG2976	Protein conserved in bacteria
HV191_RS06550	COG3104	oligopeptide transport
HV191_RS06560	COG1645	bacterial-type flagellum-dependent swarming motility
HV191_RS06565	COG1570	exodeoxyribonuclease VII activity
HV191_RS06570	COG0517	IMP dehydrogenase activity
HV191_RS06570	COG0516	GMP reductase activity
HV191_RS06585	COG2200	EAL domain
HV191_RS06600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV191_RS06610	COG2723	6-phospho-beta-galactosidase activity
HV191_RS06620	COG2233	PERMEase
HV191_RS06630	COG1393	Belongs to the ArsC family
HV191_RS06635	COG4783	chaperone-mediated protein folding
HV191_RS06640	COG0628	permease
HV191_RS06645	COG3366	ferrous iron transmembrane transporter activity
HV191_RS06650	COG0700	Nucleoside recognition
HV191_RS06655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV191_RS06660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV191_RS06665	COG2716	regulation of RNA biosynthetic process
HV191_RS06675	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV191_RS06685	COG2321	neutral zinc metallopeptidase
HV191_RS06695	COG0400	carboxylic ester hydrolase activity
HV191_RS06710	COG1393	Belongs to the ArsC family
HV191_RS06720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV191_RS06725	COG3850	Histidine kinase
HV191_RS06730	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS06730	COG0493	'glutamate synthase
HV191_RS06740	COG5342	invasion associated locus B
HV191_RS06745	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV191_RS06765	COG4766	ethanolamine catabolic process
HV191_RS06770	COG4812	Cobalamin adenosyltransferase
HV191_RS06835	COG2207	Transcriptional regulator
HV191_RS06845	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV191_RS06865	COG2837	iron assimilation
HV191_RS06870	COG0165	Argininosuccinate lyase
HV191_RS06880	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV191_RS06885	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV191_RS06890	COG2186	Transcriptional regulator
HV191_RS06900	COG4150	thiosulfate binding
HV191_RS06905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV191_RS06910	COG4208	sulfate ABC transporter
HV191_RS06915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV191_RS06980	COG3530	Putative quorum-sensing-regulated virulence factor
HV191_RS06985	COG0385	Bile acid
HV191_RS06990	COG0583	DNA-binding transcription factor activity
HV191_RS07025	COG3415	Transposase
HV191_RS07030	COG3415	Transposase
HV191_RS07045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV191_RS07060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV191_RS07065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV191_RS07070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS07070	COG1263	PTS System
HV191_RS07080	COG0667	Aldo Keto reductase
HV191_RS07085	COG3961	Belongs to the TPP enzyme family
HV191_RS07105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS07110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS07115	COG0006	proline dipeptidase activity
HV191_RS07120	COG1363	Peptidase, m42
HV191_RS07135	COG2207	Transcriptional regulator
HV191_RS07140	COG3279	Response regulator of the LytR AlgR family
HV191_RS07145	COG3275	phosphorelay sensor kinase activity
HV191_RS07150	COG0436	Aminotransferase
HV191_RS07165	COG1560	Kdo2-lipid A biosynthetic process
HV191_RS07195	COG3122	Protein conserved in bacteria
HV191_RS07200	COG0840	transmembrane signaling receptor activity
HV191_RS07205	COG1446	asparaginase
HV191_RS07260	COG0582	viral genome integration into host DNA
HV191_RS07270	COG0582	viral genome integration into host DNA
HV191_RS07400	COG3179	chitinase
HV191_RS07425	COG1802	Transcriptional regulator
HV191_RS07425	COG4626	Terminase
HV191_RS07435	COG4695	Portal protein
HV191_RS07545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV191_RS07560	COG2116	formate transmembrane transporter activity
HV191_RS07570	COG2067	long-chain fatty acid transport protein
HV191_RS07575	COG3691	Protein conserved in bacteria
HV191_RS07590	COG2062	phosphohistidine phosphatase, SixA
HV191_RS07615	COG0730	response to heat
HV191_RS07620	COG3101	peptidyl-lysine hydroxylation
HV191_RS07635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV191_RS07680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV191_RS07690	COG0586	Pfam SNARE associated Golgi protein
HV191_RS07700	COG0285	dihydrofolate synthase activity
HV191_RS07705	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV191_RS07710	COG1286	toxin biosynthetic process
HV191_RS07715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV191_RS07720	COG0163	prenyltransferase activity
HV191_RS07730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV191_RS07745	COG4598	ABC transporter
HV191_RS07750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV191_RS07755	COG1090	epimerase
HV191_RS07760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV191_RS07765	COG0625	glutathione transferase activity
HV191_RS07770	COG0625	glutathione transferase activity
HV191_RS07775	COG0622	Phosphoesterase
HV191_RS07785	COG1288	antiporter activity
HV191_RS07810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV191_RS07815	COG0490	domain, Protein
HV191_RS07815	COG0471	metal ion transport
HV191_RS07825	COG0436	Aminotransferase
HV191_RS07830	COG0583	DNA-binding transcription factor activity
HV191_RS07850	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HV191_RS07875	COG0839	Belongs to the complex I subunit 6 family
HV191_RS07885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV191_RS07890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV191_RS07900	COG0784	Response regulator, receiver
HV191_RS07900	COG0835	chemotaxis
HV191_RS07910	COG2153	protein acetylation
HV191_RS07915	COG4575	ribosome binding
HV191_RS07920	COG1169	isochorismate synthase
HV191_RS08005	COG1414	Transcriptional regulator
HV191_RS08015	COG2271	Major facilitator Superfamily
HV191_RS08035	COG0247	lactate metabolic process
HV191_RS08045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV191_RS08055	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS08065	COG0584	glycerophosphoryl diester phosphodiesterase
HV191_RS08070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV191_RS08095	COG0183	Belongs to the thiolase family
HV191_RS08100	COG2031	fatty acid transporter
HV191_RS08105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV191_RS08110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV191_RS08115	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS08120	COG2204	response regulator
HV191_RS08125	COG3852	Histidine kinase
HV191_RS08140	COG2198	Histidine kinase
HV191_RS08140	COG0642	Histidine kinase
HV191_RS08150	COG1477	protein flavinylation
HV191_RS08155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV191_RS08155	COG2169	Transcriptional regulator
HV191_RS08160	COG3145	DNA-N1-methyladenine dioxygenase activity
HV191_RS08165	COG4615	Cyclic peptide transporter
HV191_RS08170	COG2239	Acts as a magnesium transporter
HV191_RS08175	COG0659	secondary active sulfate transmembrane transporter activity
HV191_RS08190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS08190	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV191_RS08195	COG3062	negative regulation of establishment of protein localization
HV191_RS08205	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS08210	COG0348	domain, Protein
HV191_RS08215	COG3043	anaerobic respiration
HV191_RS08220	COG3005	denitrification pathway
HV191_RS08225	COG4133	protoheme IX ABC transporter activity
HV191_RS08235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV191_RS08240	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV191_RS08250	COG1138	Cytochrome C-type biogenesis protein
HV191_RS08255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV191_RS08260	COG3088	subunit of a heme lyase
HV191_RS08260	COG4235	cytochrome complex assembly
HV191_RS08265	COG2197	response regulator
HV191_RS08295	COG1061	Type III restriction enzyme res subunit
HV191_RS08300	COG1187	pseudouridine synthase activity
HV191_RS08305	COG2814	Major facilitator Superfamily
HV191_RS08315	COG4172	Belongs to the ABC transporter superfamily
HV191_RS08320	COG4239	(ABC) transporter, permease
HV191_RS08325	COG4174	ABC transporter (Permease)
HV191_RS08330	COG4166	transmembrane transport
HV191_RS08335	COG2200	EAL domain
HV191_RS08340	COG0791	NLP P60 protein
HV191_RS08345	COG0671	phosphoesterase, PA-phosphatase related
HV191_RS08350	COG0523	cobalamin synthesis protein
HV191_RS08355	COG0246	Mannitol dehydrogenase
HV191_RS08360	COG1312	Catalyzes the dehydration of D-mannonate
HV191_RS08365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV191_RS08370	COG3005	denitrification pathway
HV191_RS08380	COG3381	protein complex oligomerization
HV191_RS08405	COG1105	Belongs to the carbohydrate kinase PfkB family
HV191_RS08410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV191_RS08410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS08410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS08415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV191_RS08425	COG0583	DNA-binding transcription factor activity
HV191_RS08430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS08435	COG2313	pseudouridylate synthase activity
HV191_RS08440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV191_RS08445	COG1522	sequence-specific DNA binding
HV191_RS08445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS08455	COG2855	membrane
HV191_RS08460	COG0583	DNA-binding transcription factor activity
HV191_RS08465	COG0833	amino acid
HV191_RS08470	COG4771	TonB-dependent receptor
HV191_RS08485	COG2311	Membrane
HV191_RS08500	COG1129	ABC transporter
HV191_RS08515	COG0493	'glutamate synthase
HV191_RS08525	COG2949	membrane
HV191_RS08535	COG1346	cytolysis
HV191_RS08550	COG2271	Major facilitator Superfamily
HV191_RS08565	COG0625	glutathione transferase activity
HV191_RS08570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV191_RS08575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV191_RS08580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV191_RS08590	COG0586	Pfam SNARE associated Golgi protein
HV191_RS08600	COG1686	Belongs to the peptidase S11 family
HV191_RS08605	COG0277	FAD linked oxidase domain protein
HV191_RS08610	COG1472	Belongs to the glycosyl hydrolase 3 family
HV191_RS08615	COG1732	Glycine betaine
HV191_RS08620	COG1174	glycine betaine transport
HV191_RS08625	COG1125	glycine betaine transport
HV191_RS08630	COG1174	glycine betaine transport
HV191_RS08640	COG0789	Transcriptional regulator
HV191_RS08645	COG3275	phosphorelay sensor kinase activity
HV191_RS08655	COG4807	Protein conserved in bacteria
HV191_RS08660	COG4808	Protein conserved in bacteria
HV191_RS08675	COG3039	Transposase
HV191_RS08680	COG3121	Chaperone
HV191_RS08685	COG3188	usher protein
HV191_RS08695	COG5455	response to cobalt ion
HV191_RS08775	COG0351	phosphomethylpyrimidine kinase
HV191_RS08780	COG2188	Transcriptional regulator
HV191_RS08785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS08790	COG1397	ADP-ribosylglycohydrolase
HV191_RS08795	COG2211	Major facilitator Superfamily
HV191_RS08800	COG1830	Aldolase
HV191_RS08810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV191_RS08815	COG4160	amino acid transport
HV191_RS08820	COG4215	(ABC) transporter
HV191_RS08825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV191_RS08830	COG1126	abc transporter atp-binding protein
HV191_RS08845	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV191_RS08850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV191_RS08855	COG0702	epimerase
HV191_RS08860	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV191_RS08865	COG0028	Belongs to the TPP enzyme family
HV191_RS08875	COG4529	Protein conserved in bacteria
HV191_RS08880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV191_RS08890	COG2431	L-lysine efflux transmembrane transporter activity
HV191_RS08900	COG3593	DNA synthesis involved in DNA repair
HV191_RS08905	COG2990	Protein conserved in bacteria
HV191_RS08910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS08920	COG1278	Cold shock
HV191_RS08930	COG0542	response to heat
HV191_RS08940	COG0745	RESPONSE REGULATOR receiver
HV191_RS08945	COG2205	protein histidine kinase activity
HV191_RS08975	COG0443	Heat shock 70 kDa protein
HV191_RS08980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV191_RS08985	COG5002	protein histidine kinase activity
HV191_RS08985	COG3447	MASE1 domain protein
HV191_RS08985	COG5001	Diguanylate cyclase
HV191_RS09000	COG2982	Protein involved in outer membrane biogenesis
HV191_RS09005	COG1253	flavin adenine dinucleotide binding
HV191_RS09025	COG0463	Glycosyl transferase, family 2
HV191_RS09030	COG1045	serine acetyltransferase
HV191_RS09035	COG0438	transferase activity, transferring glycosyl groups
HV191_RS09045	COG1216	Glycosyl transferase, family 2
HV191_RS09050	COG0110	maltose O-acetyltransferase activity
HV191_RS09055	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HV191_RS09060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV191_RS09065	COG1051	belongs to the nudix hydrolase family
HV191_RS09070	COG0297	glycogen (starch) synthase activity
HV191_RS09075	COG0662	Cupin 2, conserved barrel domain protein
HV191_RS09075	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HV191_RS09080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HV191_RS09085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV191_RS09090	COG2244	polysaccharide biosynthetic process
HV191_RS09095	COG2327	Polysaccharide pyruvyl transferase
HV191_RS09135	COG0438	transferase activity, transferring glycosyl groups
HV191_RS09145	COG2801	Transposase and inactivated derivatives
HV191_RS09160	COG0500	methyltransferase
HV191_RS09170	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HV191_RS09180	COG3039	Transposase
HV191_RS09215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV191_RS09235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV191_RS09265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV191_RS09270	COG0583	DNA-binding transcription factor activity
HV191_RS09280	COG0531	amino acid
HV191_RS09285	COG2925	Exonuclease
HV191_RS09315	COG1289	transmembrane transporter activity
HV191_RS09350	COG4656	Part of a membrane complex involved in electron transport
HV191_RS09360	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS09540	COG1376	ErfK ybiS ycfS ynhG family protein
HV191_RS09550	COG1178	ABC-type Fe3 transport system permease component
HV191_RS09555	COG1840	ABC-type Fe3 transport system, periplasmic component
HV191_RS09595	COG1418	mRNA catabolic process
HV191_RS09600	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV191_RS09605	COG3727	T/G mismatch-specific endonuclease activity
HV191_RS09610	COG0697	spore germination
HV191_RS09615	COG2354	Protein conserved in bacteria
HV191_RS09620	COG5475	Uncharacterized small protein (DUF2158)
HV191_RS09680	COG2882	bacterial-type flagellum organization
HV191_RS09710	COG0425	Belongs to the sulfur carrier protein TusA family
HV191_RS09725	COG0366	Alpha amylase catalytic
HV191_RS09770	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HV191_RS09785	COG2197	response regulator
HV191_RS09795	COG2197	response regulator
HV191_RS09855	COG3039	Transposase
HV191_RS09865	COG1528	Iron-storage protein
HV191_RS09875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV191_RS09915	COG0789	Transcriptional regulator
HV191_RS09930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV191_RS09940	COG0589	response to stress
HV191_RS09960	COG4644	lycopene metabolic process
HV191_RS09990	COG0058	SHG alpha-glucan phosphorylase activity
HV191_RS09995	COG0033	Phosphoglucomutase
HV191_RS10035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV191_RS10110	COG0625	glutathione transferase activity
HV191_RS10115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV191_RS10125	COG0583	DNA-binding transcription factor activity
HV191_RS10135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV191_RS10150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HV191_RS10170	COG1846	Transcriptional regulator
HV191_RS10175	COG0583	DNA-binding transcription factor activity
HV191_RS10185	COG2948	multi-organism process
HV191_RS10230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV191_RS10250	COG0789	Transcriptional regulator
HV191_RS10290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV191_RS10305	COG1342	Belongs to the UPF0251 family
HV191_RS10320	COG0783	Belongs to the Dps family
HV191_RS10325	COG0640	Transcriptional regulator
HV191_RS10330	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV191_RS10355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV191_RS10360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV191_RS10375	COG3423	Transcriptional regulator
HV191_RS10535	COG2974	May be involved in recombination
HV191_RS10590	COG1802	Transcriptional regulator
HV191_RS10645	COG2801	Transposase and inactivated derivatives
HV191_RS10655	COG2801	Transposase and inactivated derivatives
HV191_RS10680	COG3344	reverse transcriptase
HV191_RS10695	COG1278	Cold shock
HV191_RS10715	COG3459	Glycosyltransferase 36 associated
HV191_RS10740	COG2850	peptidyl-arginine hydroxylation
HV191_RS10765	COG0582	viral genome integration into host DNA
HV191_RS10775	COG0582	viral genome integration into host DNA
HV191_RS10800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV191_RS10810	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV191_RS10815	COG0739	heme binding
HV191_RS10820	COG1560	Kdo2-lipid A biosynthetic process
HV191_RS10830	COG1737	Transcriptional regulator
HV191_RS10835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV191_RS10840	COG0129	dihydroxy-acid dehydratase activity
HV191_RS10845	COG0800	Aldolase
HV191_RS10855	COG3141	response to X-ray
HV191_RS10865	COG2979	Protein of unknown function (DUF533)
HV191_RS10870	COG1770	oligopeptidase
HV191_RS10875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV191_RS10880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV191_RS10890	COG2372	response to copper ion
HV191_RS10895	COG1276	copper resistance
HV191_RS10905	COG0582	viral genome integration into host DNA
HV191_RS10935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV191_RS10995	COG1484	DNA-dependent DNA replication
HV191_RS11180	COG1196	nuclear chromosome segregation
HV191_RS11255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV191_RS11260	COG2135	peptidase activity
HV191_RS11290	COG3008	intermembrane lipid transfer
HV191_RS11295	COG2995	paraquat-inducible protein a
HV191_RS11300	COG1956	GAF domain-containing protein
HV191_RS11320	COG4771	TonB-dependent receptor
HV191_RS11325	COG0747	negative chemotaxis
HV191_RS11330	COG0601	transmembrane transport
HV191_RS11335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV191_RS11350	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV191_RS11360	COG3615	Tellurite resistance protein tehB
HV191_RS11375	COG3383	formate dehydrogenase (NAD+) activity
HV191_RS11380	COG2261	transglycosylase associated protein
HV191_RS11395	COG2203	Gaf domain
HV191_RS11395	COG2199	diguanylate cyclase activity
HV191_RS11400	COG3042	response to heat
HV191_RS11405	COG3189	MarR family transcriptional regulator
HV191_RS11410	COG0504	CTP synthase activity
HV191_RS11415	COG2807	transmembrane transport
HV191_RS11420	COG2207	Transcriptional regulator
HV191_RS11430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV191_RS11435	COG2199	diguanylate cyclase activity
HV191_RS11440	COG2226	methyltransferase
HV191_RS11450	COG0110	maltose O-acetyltransferase activity
HV191_RS11460	COG2766	serine protein kinase
HV191_RS11465	COG3713	MltA-interacting MipA family protein
HV191_RS11480	COG0656	L-ascorbic acid biosynthetic process
HV191_RS11500	COG3139	Protein of unknown function (DUF1315)
HV191_RS11515	COG1335	isochorismatase
HV191_RS11520	COG0252	asparaginase activity
HV191_RS11525	COG0616	signal peptide processing
HV191_RS11530	COG0778	Nitroreductase
HV191_RS11540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV191_RS11555	COG0494	nUDIX hydrolase
HV191_RS11560	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV191_RS11565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV191_RS11570	COG2897	thiosulfate sulfurtransferase activity
HV191_RS11575	COG4136	ATPase activity
HV191_RS11580	COG4135	transport system, permease component
HV191_RS11585	COG4134	Bacterial extracellular solute-binding protein
HV191_RS11590	COG0398	Pfam SNARE associated Golgi protein
HV191_RS11595	COG0398	Pfam SNARE associated Golgi protein
HV191_RS11600	COG0708	Exodeoxyribonuclease III
HV191_RS11630	COG3678	ATP-independent chaperone mediated protein folding
HV191_RS11640	COG0322	excinuclease ABC activity
HV191_RS11650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV191_RS11655	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV191_RS11660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV191_RS11665	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV191_RS11670	COG1917	Cupin 2, conserved barrel domain protein
HV191_RS11670	COG2169	Transcriptional regulator
HV191_RS11675	COG1486	melibiose metabolic process
HV191_RS11685	COG0753	catalase activity
HV191_RS11700	COG1988	membrane-bound metal-dependent
HV191_RS11710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV191_RS11720	COG3001	Fructosamine kinase
HV191_RS11725	COG1105	Belongs to the carbohydrate kinase PfkB family
HV191_RS11730	COG3137	Salt-induced outer membrane protein
HV191_RS11750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HV191_RS11780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV191_RS11795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS11810	COG0386	Belongs to the glutathione peroxidase family
HV191_RS11820	COG0791	NLP P60 protein
HV191_RS11840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV191_RS11845	COG4558	Periplasmic binding protein
HV191_RS11850	COG3720	iron ion transport
HV191_RS11855	COG4771	TonB-dependent receptor
HV191_RS11860	COG4256	Hemin uptake protein
HV191_RS11865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV191_RS11875	COG0574	Belongs to the PEP-utilizing enzyme family
HV191_RS11875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV191_RS11880	COG0318	PFAM AMP-dependent synthetase and ligase
HV191_RS11885	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HV191_RS11890	COG0644	oxidoreductase
HV191_RS11895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HV191_RS11900	COG2086	electron transfer activity
HV191_RS11905	COG2207	Transcriptional regulator
HV191_RS11905	COG1917	Cupin 2, conserved barrel domain protein
HV191_RS11910	COG1960	acyl-CoA dehydrogenase activity
HV191_RS11915	COG4670	ketone body catabolic process
HV191_RS11930	COG2271	Major facilitator Superfamily
HV191_RS11935	COG0738	Major facilitator superfamily
HV191_RS11950	COG0628	permease
HV191_RS11955	COG0247	lactate metabolic process
HV191_RS11955	COG0277	FAD linked oxidase domain protein
HV191_RS11960	COG2050	protein possibly involved in aromatic compounds catabolism
HV191_RS11990	COG0316	Belongs to the HesB IscA family
HV191_RS11995	COG0719	Fe-S assembly protein
HV191_RS12000	COG0396	ATPase activity
HV191_RS12005	COG0719	Fe-S assembly protein
HV191_RS12020	COG1376	ErfK ybiS ycfS ynhG family protein
HV191_RS12040	COG2011	ABC-type metal ion transport system permease component
HV191_RS12045	COG1464	Belongs to the NlpA lipoprotein family
HV191_RS12080	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS12085	COG2414	aldehyde ferredoxin oxidoreductase
HV191_RS12095	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS12100	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HV191_RS12110	COG0765	amino acid transport
HV191_RS12115	COG0765	amino acid transport
HV191_RS12125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV191_RS12135	COG1113	amino acid transport
HV191_RS12150	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS12160	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HV191_RS12175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV191_RS12210	COG0386	Belongs to the glutathione peroxidase family
HV191_RS12220	COG4977	sequence-specific DNA binding
HV191_RS12260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HV191_RS12270	COG1942	4-Oxalocrotonate Tautomerase
HV191_RS12285	COG0477	Major facilitator Superfamily
HV191_RS12290	COG0583	DNA-binding transcription factor activity
HV191_RS12300	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS12320	COG0628	permease
HV191_RS12325	COG3272	Protein of unknown function (DUF1722)
HV191_RS12330	COG5001	Diguanylate cyclase
HV191_RS12330	COG3300	MHYT domain
HV191_RS12355	COG0251	oxidation-reduction process
HV191_RS12370	COG0564	pseudouridine synthase activity
HV191_RS12380	COG0307	riboflavin synthase, alpha
HV191_RS12390	COG2814	Major facilitator Superfamily
HV191_RS12395	COG0583	DNA-binding transcription factor activity
HV191_RS12410	COG2814	Major facilitator Superfamily
HV191_RS12415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV191_RS12420	COG0791	NLP P60 protein
HV191_RS12425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV191_RS12435	COG0346	lactoylglutathione lyase activity
HV191_RS12440	COG1902	pentaerythritol trinitrate reductase activity
HV191_RS12445	COG1309	transcriptional regulator
HV191_RS12450	COG3313	Fe-S protein
HV191_RS12455	COG4989	oxidoreductase activity
HV191_RS12470	COG1566	PFAM secretion protein HlyD family protein
HV191_RS12495	COG3895	Periplasmic Protein
HV191_RS12510	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HV191_RS12515	COG0625	glutathione transferase activity
HV191_RS12525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV191_RS12575	COG0673	inositol 2-dehydrogenase activity
HV191_RS12585	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV191_RS12590	COG1263	PTS System
HV191_RS12590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS12595	COG1609	Transcriptional regulator
HV191_RS12600	COG5339	Protein conserved in bacteria
HV191_RS12605	COG1482	cell wall glycoprotein biosynthetic process
HV191_RS12610	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS12610	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS12625	COG2205	protein histidine kinase activity
HV191_RS12635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV191_RS12645	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV191_RS12650	COG0745	RESPONSE REGULATOR receiver
HV191_RS12655	COG3136	membrane protein required for alginate biosynthesis
HV191_RS12665	COG0531	amino acid
HV191_RS12675	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV191_RS12680	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV191_RS12685	COG2814	Major facilitator Superfamily
HV191_RS12690	COG0628	permease
HV191_RS12705	COG3591	Belongs to the peptidase S1B family
HV191_RS12715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV191_RS12730	COG0745	RESPONSE REGULATOR receiver
HV191_RS12735	COG5002	protein histidine kinase activity
HV191_RS12745	COG2814	Major facilitator Superfamily
HV191_RS12750	COG0583	DNA-binding transcription factor activity
HV191_RS12755	COG1940	carbohydrate kinase activity
HV191_RS12760	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV191_RS12770	COG3381	protein complex oligomerization
HV191_RS12775	COG3302	dmso reductase anchor subunit
HV191_RS12780	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS12785	COG0243	molybdopterin cofactor binding
HV191_RS12800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV191_RS12815	COG4948	Mandelate Racemase Muconate Lactonizing
HV191_RS12820	COG1063	alcohol dehydrogenase
HV191_RS12825	COG0477	Major facilitator Superfamily
HV191_RS12830	COG0246	Mannitol dehydrogenase
HV191_RS12840	COG1802	Transcriptional regulator
HV191_RS12845	COG4221	oxidoreductase activity
HV191_RS12850	COG0339	signal peptide processing
HV191_RS12875	COG1129	ABC transporter
HV191_RS12880	COG0410	ABC transporter
HV191_RS12885	COG2814	Major facilitator Superfamily
HV191_RS12890	COG0697	spore germination
HV191_RS12905	COG1846	Transcriptional regulator
HV191_RS12920	COG0583	DNA-binding transcription factor activity
HV191_RS12925	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS12950	COG3781	membrane
HV191_RS12970	COG2801	Transposase and inactivated derivatives
HV191_RS12980	COG2801	Transposase and inactivated derivatives
HV191_RS12990	COG2801	Transposase and inactivated derivatives
HV191_RS13000	COG4628	conserved protein (DUF2132)
HV191_RS13010	COG0840	transmembrane signaling receptor activity
HV191_RS13025	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HV191_RS13030	COG0747	negative chemotaxis
HV191_RS13035	COG0601	transmembrane transport
HV191_RS13040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV191_RS13045	COG0444	Belongs to the ABC transporter superfamily
HV191_RS13050	COG4608	Belongs to the ABC transporter superfamily
HV191_RS13060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV191_RS13065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV191_RS13075	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV191_RS13075	COG0824	Thioesterase
HV191_RS13080	COG2610	gluconate transmembrane transporter activity
HV191_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS13090	COG1764	response to oxidative stress
HV191_RS13110	COG2864	formate dehydrogenase
HV191_RS13115	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS13130	COG3039	Transposase
HV191_RS13160	COG2223	nitrite transmembrane transporter activity
HV191_RS13165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV191_RS13170	COG1140	nitrate reductase beta subunit
HV191_RS13175	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV191_RS13180	COG2181	nitrate reductase activity
HV191_RS13185	COG0384	phenazine biosynthesis protein PhzF
HV191_RS13190	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV191_RS13195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV191_RS13205	COG1609	Transcriptional regulator
HV191_RS13215	COG2271	Major facilitator Superfamily
HV191_RS13220	COG0625	glutathione transferase activity
HV191_RS13225	COG1126	abc transporter atp-binding protein
HV191_RS13245	COG1473	amidohydrolase
HV191_RS13250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV191_RS13255	COG0840	transmembrane signaling receptor activity
HV191_RS13275	COG4772	TonB-dependent receptor
HV191_RS13280	COG2130	NADP-dependent
HV191_RS13290	COG1247	-acetyltransferase
HV191_RS13295	COG3238	Protein conserved in bacteria
HV191_RS13305	COG0747	negative chemotaxis
HV191_RS13340	COG2814	Major facilitator Superfamily
HV191_RS13350	COG1177	transmembrane transport
HV191_RS13355	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV191_RS13360	COG3842	ATPase activity
HV191_RS13365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV191_RS13370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV191_RS13375	COG1598	PFAM Uncharacterised protein family UPF0150
HV191_RS13380	COG1724	mRNA binding
HV191_RS13385	COG1271	oxidase subunit
HV191_RS13390	COG1294	oxidase, subunit
HV191_RS13405	COG0826	peptidase U32
HV191_RS13410	COG1396	sequence-specific DNA binding
HV191_RS13415	COG3135	benzoate transporter
HV191_RS13425	COG0697	spore germination
HV191_RS13435	COG0500	methyltransferase
HV191_RS13445	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV191_RS13450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV191_RS13455	COG2841	Protein conserved in bacteria
HV191_RS13465	COG5383	Protein conserved in bacteria
HV191_RS13470	COG1227	inorganic diphosphatase activity
HV191_RS13475	COG0583	DNA-binding transcription factor activity
HV191_RS13480	COG0840	transmembrane signaling receptor activity
HV191_RS13500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV191_RS13505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV191_RS13510	COG3038	cytochrome b561
HV191_RS13515	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS13520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV191_RS13525	COG1643	Atp-dependent helicase
HV191_RS13545	COG0671	phosphoesterase, PA-phosphatase related
HV191_RS13545	COG2453	phosphatase
HV191_RS13550	COG2267	carboxylic ester hydrolase activity
HV191_RS13560	COG4589	Belongs to the CDS family
HV191_RS13565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV191_RS13570	COG3784	Protein of unknown function (DUF1318)
HV191_RS13585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV191_RS13590	COG3187	Heat shock protein
HV191_RS13595	COG3042	response to heat
HV191_RS13600	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV191_RS13600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV191_RS13600	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV191_RS13600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV191_RS13605	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV191_RS13615	COG0589	response to stress
HV191_RS13625	COG0513	Belongs to the DEAD box helicase family
HV191_RS13640	COG0840	transmembrane signaling receptor activity
HV191_RS13650	COG3706	GGDEF domain
HV191_RS13655	COG2840	Smr protein MutS2
HV191_RS13675	COG3182	Iron-regulated membrane protein
HV191_RS13680	COG0668	transmembrane transport
HV191_RS13695	COG0346	lactoylglutathione lyase activity
HV191_RS13700	COG1349	DNA-binding transcription factor activity
HV191_RS13705	COG4166	transmembrane transport
HV191_RS13710	COG2866	Carboxypeptidase
HV191_RS13715	COG4948	Mandelate Racemase Muconate Lactonizing
HV191_RS13720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV191_RS13735	COG3106	COG3106 Predicted ATPase
HV191_RS13740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV191_RS13745	COG1609	Transcriptional regulator
HV191_RS13760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV191_RS13765	COG1554	hydrolase, family 65, central catalytic
HV191_RS13770	COG0673	inositol 2-dehydrogenase activity
HV191_RS13775	COG1082	Xylose isomerase domain protein TIM barrel
HV191_RS13780	COG1063	alcohol dehydrogenase
HV191_RS13785	COG0395	ABC-type sugar transport system, permease component
HV191_RS13790	COG1175	transmembrane transport
HV191_RS13795	COG1653	transport
HV191_RS13800	COG0366	Alpha amylase catalytic
HV191_RS13810	COG1983	PspC domain protein
HV191_RS13820	COG1842	Phage shock protein A
HV191_RS13825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV191_RS13830	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS13845	COG4171	peptide transport system, permease
HV191_RS13850	COG4172	Belongs to the ABC transporter superfamily
HV191_RS13870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV191_RS13875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV191_RS13875	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV191_RS13885	COG5001	Diguanylate cyclase
HV191_RS13895	COG1349	DNA-binding transcription factor activity
HV191_RS13905	COG0023	Translation Initiation Factor
HV191_RS13915	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV191_RS13920	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV191_RS13925	COG0671	phosphoesterase, PA-phosphatase related
HV191_RS13935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV191_RS13950	COG0583	DNA-binding transcription factor activity
HV191_RS13965	COG0616	signal peptide processing
HV191_RS13970	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS13980	COG1187	pseudouridine synthase activity
HV191_RS13985	COG0009	L-threonylcarbamoyladenylate synthase
HV191_RS13990	COG0613	PHP domain protein
HV191_RS14025	COG3706	GGDEF domain
HV191_RS14035	COG3047	cAMP biosynthetic process
HV191_RS14060	COG2350	Protein conserved in bacteria
HV191_RS14080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV191_RS14090	COG0444	Belongs to the ABC transporter superfamily
HV191_RS14110	COG2095	MarC family integral membrane protein
HV191_RS14115	COG1454	alcohol dehydrogenase
HV191_RS14115	COG1012	belongs to the aldehyde dehydrogenase family
HV191_RS14120	COG1435	thymidine kinase activity
HV191_RS14125	COG3039	Transposase
HV191_RS14135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV191_RS14140	COG0745	RESPONSE REGULATOR receiver
HV191_RS14145	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV191_RS14155	COG0788	formyltetrahydrofolate deformylase activity
HV191_RS14170	COG2181	nitrate reductase activity
HV191_RS14175	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV191_RS14180	COG1140	nitrate reductase beta subunit
HV191_RS14185	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV191_RS14190	COG2223	nitrite transmembrane transporter activity
HV191_RS14195	COG3850	Histidine kinase
HV191_RS14200	COG2197	response regulator
HV191_RS14205	COG4932	domain protein
HV191_RS14210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV191_RS14220	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV191_RS14225	COG4572	Cation transport regulator
HV191_RS14230	COG0387	Pfam Sodium calcium exchanger
HV191_RS14250	COG2890	protein-(glutamine-N5) methyltransferase activity
HV191_RS14280	COG0659	secondary active sulfate transmembrane transporter activity
HV191_RS14285	COG0076	glutamate decarboxylase activity
HV191_RS14290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV191_RS14295	COG0527	aspartate kinase activity
HV191_RS14310	COG0012	GTP binding
HV191_RS14315	COG0582	viral genome integration into host DNA
HV191_RS14380	COG4974	Belongs to the 'phage' integrase family
HV191_RS14390	COG2003	Belongs to the UPF0758 family
HV191_RS14405	COG1396	sequence-specific DNA binding
HV191_RS14465	COG5002	protein histidine kinase activity
HV191_RS14505	COG2149	membrane
HV191_RS14510	COG1737	Transcriptional regulator
HV191_RS14525	COG2190	(PTS) system
HV191_RS14525	COG1263	PTS System
HV191_RS14525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS14530	COG0641	radical SAM
HV191_RS14535	COG0656	L-ascorbic acid biosynthetic process
HV191_RS14540	COG0667	Aldo Keto reductase
HV191_RS14550	COG0702	epimerase
HV191_RS14580	COG2200	EAL domain
HV191_RS14585	COG0789	Transcriptional regulator
HV191_RS14610	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV191_RS14615	COG2376	Dihydroxyacetone kinase
HV191_RS14620	COG1461	Dihydroxyacetone kinase
HV191_RS14645	COG1120	ATPase activity
HV191_RS14650	COG0500	methyltransferase
HV191_RS14655	COG0157	Belongs to the NadC ModD family
HV191_RS14680	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV191_RS14690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV191_RS14700	COG2719	SpoVR family
HV191_RS14730	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV191_RS14745	COG2894	cell division
HV191_RS14755	COG0583	DNA-binding transcription factor activity
HV191_RS14760	COG0473	3-isopropylmalate dehydrogenase activity
HV191_RS14765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV191_RS14770	COG4638	Rieske (2fe-2S)
HV191_RS14775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV191_RS14780	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV191_RS14785	COG0318	PFAM AMP-dependent synthetase and ligase
HV191_RS14790	COG3065	identical protein binding
HV191_RS14795	COG1214	PFAM Peptidase M22, glycoprotease
HV191_RS14800	COG1199	ATP-dependent helicase activity
HV191_RS14805	COG0251	oxidation-reduction process
HV191_RS14825	COG1760	l-serine dehydratase
HV191_RS14830	COG2200	EAL domain
HV191_RS14835	COG1253	flavin adenine dinucleotide binding
HV191_RS14840	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS14840	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS14845	COG3715	PTS system
HV191_RS14850	COG3716	PTS system mannose fructose sorbose family IID component
HV191_RS14865	COG2226	methyltransferase
HV191_RS14870	COG0768	penicillin binding
HV191_RS14900	COG1414	Transcriptional regulator
HV191_RS14905	COG2814	Major facilitator Superfamily
HV191_RS14910	COG0538	isocitrate dehydrogenase activity
HV191_RS14915	COG1187	pseudouridine synthase activity
HV191_RS14935	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV191_RS14940	COG2255	four-way junction helicase activity
HV191_RS14960	COG0494	nUDIX hydrolase
HV191_RS14970	COG1335	isochorismatase
HV191_RS14975	COG1801	Protein of unknown function DUF72
HV191_RS14980	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV191_RS15000	COG3102	Protein conserved in bacteria
HV191_RS15015	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV191_RS15040	COG3250	beta-galactosidase activity
HV191_RS15045	COG2814	Major facilitator Superfamily
HV191_RS15050	COG4977	sequence-specific DNA binding
HV191_RS15060	COG0745	RESPONSE REGULATOR receiver
HV191_RS15075	COG0840	transmembrane signaling receptor activity
HV191_RS15085	COG1301	dicarboxylic acid transport
HV191_RS15090	COG0835	chemotaxis
HV191_RS15135	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS15140	COG1129	ABC transporter
HV191_RS15145	COG1879	ABC-type sugar transport system periplasmic component
HV191_RS15155	COG1528	Iron-storage protein
HV191_RS15165	COG0477	Major facilitator Superfamily
HV191_RS15180	COG1528	Iron-storage protein
HV191_RS15190	COG0814	amino acid
HV191_RS15195	COG3012	SEC-C Motif Domain Protein
HV191_RS15195	COG3318	Belongs to the UPF0149 family
HV191_RS15200	COG2608	mercury ion transmembrane transporter activity
HV191_RS15210	COG1305	Transglutaminase-like
HV191_RS15240	COG0640	Transcriptional regulator
HV191_RS15245	COG0431	NADPH-dependent FMN reductase
HV191_RS15275	COG1289	transmembrane transporter activity
HV191_RS15290	COG1278	Cold shock
HV191_RS15305	COG1177	transmembrane transport
HV191_RS15315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV191_RS15325	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV191_RS15330	COG1136	(ABC) transporter
HV191_RS15335	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV191_RS15340	COG4763	Acyl-transferase
HV191_RS15345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV191_RS15350	COG1376	ErfK ybiS ycfS ynhG family protein
HV191_RS15350	COG1388	LysM domain
HV191_RS15360	COG1309	transcriptional regulator
HV191_RS15370	COG3134	Outer membrane lipoprotein
HV191_RS15375	COG1252	NADH dehydrogenase
HV191_RS15400	COG5633	Lipoprotein
HV191_RS15405	COG0537	adenosine 5'-monophosphoramidase activity
HV191_RS15410	COG4773	Receptor
HV191_RS15420	COG0534	Mate efflux family protein
HV191_RS15430	COG0582	viral genome integration into host DNA
HV191_RS15455	COG3423	Transcriptional regulator
HV191_RS15475	COG3039	Transposase
HV191_RS15490	COG0583	DNA-binding transcription factor activity
HV191_RS15510	COG0477	Major facilitator Superfamily
HV191_RS15515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV191_RS15520	COG0006	proline dipeptidase activity
HV191_RS15530	COG0084	hydrolase, TatD family'
HV191_RS15535	COG0470	DNA polymerase III
HV191_RS15545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV191_RS15550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV191_RS15555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV191_RS15590	COG1399	metal-binding, possibly nucleic acid-binding protein
HV191_RS15600	COG0564	pseudouridine synthase activity
HV191_RS15605	COG1530	ribonuclease E activity
HV191_RS15635	COG4786	Flagellar basal body rod
HV191_RS15640	COG4787	bacterial-type flagellum-dependent cell motility
HV191_RS15655	COG1558	bacterial-type flagellum-dependent cell motility
HV191_RS15695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV191_RS15740	COG3038	cytochrome b561
HV191_RS15755	COG1560	Kdo2-lipid A biosynthetic process
HV191_RS15770	COG5645	(Lipo)protein
HV191_RS15790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV191_RS15845	COG3381	protein complex oligomerization
HV191_RS15870	COG1702	phosphate starvation-inducible protein PhoH
HV191_RS15895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV191_RS15900	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV191_RS15900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV191_RS15900	COG0506	proline dehydrogenase activity
HV191_RS15905	COG3755	Protein conserved in bacteria
HV191_RS15910	COG1309	transcriptional regulator
HV191_RS15920	COG3729	General stress protein
HV191_RS15940	COG0640	Transcriptional regulator
HV191_RS15950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV191_RS15955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV191_RS15955	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HV191_RS16005	COG0813	purine-nucleoside phosphorylase activity
HV191_RS16025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV191_RS16030	COG1120	ATPase activity
HV191_RS16045	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HV191_RS16045	COG2857	Cytochrome c1
HV191_RS16060	COG4166	transmembrane transport
HV191_RS16065	COG0670	Belongs to the BI1 family
HV191_RS16105	COG2920	part of a sulfur-relay system
HV191_RS16125	COG1832	CoA-binding protein
HV191_RS16140	COG0210	DNA helicase
HV191_RS16145	COG3304	Inner membrane component domain
HV191_RS16150	COG1289	transmembrane transporter activity
HV191_RS16155	COG3070	regulator of competence-specific genes
HV191_RS16175	COG1067	ATP-dependent peptidase activity
HV191_RS16185	COG3130	regulation of translation
HV191_RS16190	COG3009	Protein conserved in bacteria
HV191_RS16195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV191_RS16195	COG3008	intermembrane lipid transfer
HV191_RS16200	COG2995	paraquat-inducible protein a
HV191_RS16205	COG0488	(ABC) transporter
HV191_RS16215	COG3217	Mosc domain protein beta barrel domain protein
HV191_RS16215	COG0633	Ferredoxin
HV191_RS16230	COG0431	NADPH-dependent FMN reductase
HV191_RS16235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV191_RS16245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV191_RS16255	COG0308	aminopeptidase N
HV191_RS16275	COG1448	Aminotransferase
HV191_RS16280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV191_RS16285	COG3108	Peptidase M15
HV191_RS16290	COG2989	Protein conserved in bacteria
HV191_RS16300	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV191_RS16310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV191_RS16315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV191_RS16320	COG3173	Aminoglycoside phosphotransferase
HV191_RS16335	COG3214	Protein conserved in bacteria
HV191_RS16350	COG2333	competence protein COMEC
HV191_RS16350	COG0658	competence protein
HV191_RS16355	COG0776	regulation of translation
HV191_RS16360	COG0539	negative regulation of cytoplasmic translation
HV191_RS16380	COG2323	membrane
HV191_RS16385	COG1944	ATP diphosphatase activity
HV191_RS16390	COG2116	formate transmembrane transporter activity
HV191_RS16395	COG1882	Formate acetyltransferase
HV191_RS16400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV191_RS16425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV191_RS16430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS16440	COG1335	isochorismatase
HV191_RS16445	COG3302	dmso reductase anchor subunit
HV191_RS16450	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS16455	COG0243	molybdopterin cofactor binding
HV191_RS16465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV191_RS16475	COG1674	ftsk spoiiie
HV191_RS16475	COG1178	ABC-type Fe3 transport system permease component
HV191_RS16485	COG0492	ferredoxin-NADP+ reductase activity
HV191_RS16490	COG4988	ABC transporter
HV191_RS16495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV191_RS16510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV191_RS16515	COG0583	DNA-binding transcription factor activity
HV191_RS16525	COG1335	isochorismatase
HV191_RS16540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HV191_RS16550	COG1177	transmembrane transport
HV191_RS16555	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV191_RS16560	COG3842	ATPase activity
HV191_RS16565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV191_RS16605	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS16610	COG3226	Transcriptional regulator
HV191_RS16615	COG0738	Major facilitator superfamily
HV191_RS16620	COG0561	phosphatase activity
HV191_RS16630	COG2814	Major facilitator Superfamily
HV191_RS16635	COG0671	phosphoesterase, PA-phosphatase related
HV191_RS16640	COG1349	DNA-binding transcription factor activity
HV191_RS16645	COG1686	Belongs to the peptidase S11 family
HV191_RS16650	COG0625	glutathione transferase activity
HV191_RS16655	COG2133	pyrroloquinoline quinone binding
HV191_RS16690	COG1446	asparaginase
HV191_RS16700	COG0303	'Molybdopterin
HV191_RS16705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV191_RS16710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV191_RS16715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV191_RS16720	COG1882	Formate acetyltransferase
HV191_RS16725	COG0561	phosphatase activity
HV191_RS16735	COG0488	(ABC) transporter
HV191_RS16740	COG1376	ErfK ybiS ycfS ynhG family protein
HV191_RS16745	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV191_RS16760	COG2194	sulfuric ester hydrolase activity
HV191_RS16765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV191_RS16780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV191_RS16785	COG0765	amino acid transport
HV191_RS16790	COG1126	abc transporter atp-binding protein
HV191_RS16795	COG0668	transmembrane transport
HV191_RS16810	COG4774	siderophore transport
HV191_RS16820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV191_RS16830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV191_RS16835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV191_RS16845	COG0513	Belongs to the DEAD box helicase family
HV191_RS16850	COG1309	transcriptional regulator
HV191_RS16860	COG1131	(ABC) transporter
HV191_RS16865	COG0842	Transport permease protein
HV191_RS16870	COG0842	Transport permease protein
HV191_RS16880	COG3568	Endonuclease Exonuclease Phosphatase
HV191_RS16885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV191_RS16890	COG0392	lysyltransferase activity
HV191_RS16895	COG0670	Belongs to the BI1 family
HV191_RS16900	COG0314	molybdopterin synthase activity
HV191_RS16905	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV191_RS16915	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV191_RS16930	COG1757	Na H antiporter
HV191_RS16935	COG0626	cystathionine gamma-synthase activity
HV191_RS16950	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV191_RS16990	COG1881	PFAM PEBP family protein
HV191_RS17020	COG4677	pectinesterase activity
HV191_RS17035	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS17045	COG4796	Type ii and iii secretion system protein
HV191_RS17065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV191_RS17070	COG1459	type II secretion system
HV191_RS17080	COG1196	nuclear chromosome segregation
HV191_RS17080	COG0741	lytic transglycosylase activity
HV191_RS17080	COG0739	heme binding
HV191_RS17095	COG0561	phosphatase activity
HV191_RS17105	COG4149	molybdate abc transporter
HV191_RS17110	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV191_RS17120	COG2005	Transcriptional regulator
HV191_RS17120	COG3585	molybdate ion transport
HV191_RS17125	COG1119	ATPase activity
HV191_RS17130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HV191_RS17135	COG1085	galactose-1-phosphate uridylyltransferase
HV191_RS17145	COG2017	converts alpha-aldose to the beta-anomer
HV191_RS17155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV191_RS17165	COG1230	cation diffusion facilitator family transporter
HV191_RS17170	COG3201	nicotinamide mononucleotide transporter
HV191_RS17205	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV191_RS17210	COG2885	chlorophyll binding
HV191_RS17220	COG3064	Membrane
HV191_RS17225	COG0848	biopolymer transport protein
HV191_RS17230	COG0811	peptide transport
HV191_RS17235	COG0824	Thioesterase
HV191_RS17240	COG3790	cyd operon protein YbgE
HV191_RS17245	COG4890	Cyd operon protein YbgT
HV191_RS17250	COG1294	oxidase, subunit
HV191_RS17255	COG1271	oxidase subunit
HV191_RS17260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV191_RS17270	COG4865	methylaspartate mutase activity
HV191_RS17275	COG3799	methylaspartate ammonia-lyase activity
HV191_RS17290	COG1301	dicarboxylic acid transport
HV191_RS17300	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS17300	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS17310	COG0583	DNA-binding transcription factor activity
HV191_RS17315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HV191_RS17315	COG1648	precorrin-2 dehydrogenase activity
HV191_RS17335	COG3395	kinase activity
HV191_RS17340	COG0235	Class ii aldolase
HV191_RS17345	COG1349	DNA-binding transcription factor activity
HV191_RS17350	COG3622	Belongs to the hyi family
HV191_RS17355	COG3246	L-lysine catabolic process to acetate
HV191_RS17375	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV191_RS17385	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV191_RS17390	COG0567	Dehydrogenase, E1 component
HV191_RS17395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV191_RS17400	COG1053	succinate dehydrogenase
HV191_RS17405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV191_RS17410	COG2009	succinate dehydrogenase
HV191_RS17420	COG3180	Ammonia monooxygenase
HV191_RS17450	COG1984	allophanate hydrolase subunit 2
HV191_RS17455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV191_RS17470	COG5464	transposase or invertase
HV191_RS17505	COG2205	protein histidine kinase activity
HV191_RS17510	COG0745	RESPONSE REGULATOR receiver
HV191_RS17520	COG1982	Orn Lys Arg decarboxylase major
HV191_RS17525	COG0531	amino acid
HV191_RS17530	COG0033	Phosphoglucomutase
HV191_RS17535	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HV191_RS17540	COG0596	Alpha beta hydrolase
HV191_RS17550	COG0716	FMN binding
HV191_RS17560	COG0735	belongs to the Fur family
HV191_RS17570	COG2801	Transposase and inactivated derivatives
HV191_RS17575	COG0583	DNA-binding transcription factor activity
HV191_RS17580	COG1053	succinate dehydrogenase
HV191_RS17605	COG1609	Transcriptional regulator
HV191_RS17615	COG1653	transport
HV191_RS17625	COG2190	(PTS) system
HV191_RS17625	COG1263	PTS System
HV191_RS17625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS17635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV191_RS17640	COG1940	carbohydrate kinase activity
HV191_RS17640	COG1846	Transcriptional regulator
HV191_RS17645	COG0647	UMP catabolic process
HV191_RS17650	COG0367	asparagine synthase
HV191_RS17690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV191_RS17700	COG1702	phosphate starvation-inducible protein PhoH
HV191_RS17705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV191_RS17725	COG0765	amino acid transport
HV191_RS17730	COG0765	amino acid transport
HV191_RS17735	COG1126	abc transporter atp-binding protein
HV191_RS17745	COG3039	Transposase
HV191_RS17760	COG2888	peptidyl-tyrosine sulfation
HV191_RS17775	COG1466	dna polymerase III delta subunit
HV191_RS17795	COG0799	negative regulation of ribosome biogenesis
HV191_RS17805	COG0768	penicillin binding
HV191_RS17810	COG0772	Belongs to the SEDS family
HV191_RS17815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV191_RS17820	COG1686	Belongs to the peptidase S11 family
HV191_RS17845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV191_RS17865	COG3069	C4-dicarboxylate transmembrane transporter activity
HV191_RS17870	COG4565	transcriptional regulatory protein
HV191_RS17875	COG3290	protein histidine kinase activity
HV191_RS17880	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HV191_RS17890	COG2301	Belongs to the HpcH HpaI aldolase family
HV191_RS17895	COG3051	citrate lyase alpha subunit
HV191_RS17910	COG0471	metal ion transport
HV191_RS17915	COG3719	Belongs to the RNase T2 family
HV191_RS17930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV191_RS17960	COG3634	alkyl hydroperoxide reductase activity
HV191_RS17970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV191_RS17975	COG0583	DNA-binding transcription factor activity
HV191_RS17980	COG3969	phosphoadenosine phosphosulfate
HV191_RS17985	COG1475	DNA binding
HV191_RS17990	COG0436	Aminotransferase
HV191_RS17995	COG0371	Dehydrogenase
HV191_RS18000	COG2879	small protein
HV191_RS18005	COG1966	Carbon starvation protein
HV191_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS18020	COG1535	isochorismatase
HV191_RS18020	COG3433	isochorismatase activity
HV191_RS18025	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV191_RS18030	COG1169	isochorismate synthase
HV191_RS18035	COG4592	Periplasmic binding protein
HV191_RS18045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV191_RS18050	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV191_RS18055	COG1120	ATPase activity
HV191_RS18060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV191_RS18060	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV191_RS18065	COG3251	PFAM MbtH domain protein
HV191_RS18070	COG2382	esterase
HV191_RS18075	COG4771	TonB-dependent receptor
HV191_RS18085	COG1879	ABC-type sugar transport system periplasmic component
HV191_RS18095	COG1129	ABC transporter
HV191_RS18100	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS18105	COG2390	Transcriptional regulator
HV191_RS18110	COG3959	Transketolase, thiamine diphosphate binding domain
HV191_RS18115	COG3958	Transketolase
HV191_RS18125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HV191_RS18160	COG2315	Protein conserved in bacteria
HV191_RS18170	COG0668	transmembrane transport
HV191_RS18190	COG2211	Major facilitator Superfamily
HV191_RS18195	COG1113	amino acid transport
HV191_RS18225	COG5001	Diguanylate cyclase
HV191_RS18225	COG3300	MHYT domain
HV191_RS18240	COG3059	membrane
HV191_RS18250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV191_RS18255	COG2207	Transcriptional regulator
HV191_RS18260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV191_RS18265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS18270	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS18275	COG1538	Outer membrane efflux protein
HV191_RS18280	COG0745	RESPONSE REGULATOR receiver
HV191_RS18285	COG5002	protein histidine kinase activity
HV191_RS18305	COG3039	Transposase
HV191_RS18380	COG2501	S4 domain
HV191_RS18385	COG1988	membrane-bound metal-dependent
HV191_RS18395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV191_RS18405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV191_RS18410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV191_RS18420	COG2011	ABC-type metal ion transport system permease component
HV191_RS18430	COG1464	Belongs to the NlpA lipoprotein family
HV191_RS18440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV191_RS18445	COG4181	ATPase activity
HV191_RS18450	COG2755	lipolytic protein G-D-S-L family
HV191_RS18455	COG0300	oxidoreductase activity
HV191_RS18460	COG3118	belongs to the thioredoxin family
HV191_RS18465	COG0390	transport system, permease component
HV191_RS18470	COG4619	ABC transporter
HV191_RS18475	COG0330	HflC and HflK could
HV191_RS18480	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV191_RS18500	COG4771	TonB-dependent receptor
HV191_RS18505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV191_RS18515	COG3721	Heme iron utilization protein
HV191_RS18525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV191_RS18540	COG3735	TraB family
HV191_RS18545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV191_RS18555	COG2223	nitrite transmembrane transporter activity
HV191_RS18560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV191_RS18560	COG4651	solute:proton antiporter activity
HV191_RS18565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS18610	COG2832	Protein of unknown function (DUF454)
HV191_RS18615	COG3923	Primosomal replication protein n
HV191_RS18625	COG3264	Mechanosensitive ion channel
HV191_RS18625	COG1196	nuclear chromosome segregation
HV191_RS18630	COG1309	transcriptional regulator
HV191_RS18635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV191_RS18640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV191_RS18655	COG0110	maltose O-acetyltransferase activity
HV191_RS18675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV191_RS18680	COG5507	3-demethylubiquinone-9 3-methyltransferase
HV191_RS18685	COG2364	Membrane
HV191_RS18690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV191_RS18710	COG3695	enzyme binding
HV191_RS18715	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV191_RS18720	COG1946	Acyl-CoA thioesterase
HV191_RS18725	COG0004	ammonium transporteR
HV191_RS18730	COG0347	Belongs to the P(II) protein family
HV191_RS18735	COG1132	(ABC) transporter
HV191_RS18740	COG1132	(ABC) transporter
HV191_RS18745	COG1522	sequence-specific DNA binding
HV191_RS18760	COG4533	DNA binding
HV191_RS18770	COG0824	Thioesterase
HV191_RS18775	COG1555	photosystem II stabilization
HV191_RS18780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV191_RS18785	COG0776	regulation of translation
HV191_RS18790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV191_RS18810	COG0271	Belongs to the BolA IbaG family
HV191_RS18815	COG3056	Lipoprotein
HV191_RS18820	COG2223	nitrite transmembrane transporter activity
HV191_RS18825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV191_RS18830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV191_RS18835	COG1845	cytochrome c oxidase, subunit III
HV191_RS18840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV191_RS18865	COG2814	Major facilitator Superfamily
HV191_RS18900	COG0142	geranyltranstransferase activity
HV191_RS18910	COG0667	Aldo Keto reductase
HV191_RS18915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV191_RS18920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV191_RS18935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV191_RS18935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV191_RS18945	COG4238	major outer membrane lipoprotein
HV191_RS18965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV191_RS18970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV191_RS18975	COG1862	Preprotein translocase
HV191_RS18985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HV191_RS18995	COG0450	alkyl hydroperoxide reductase
HV191_RS19010	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HV191_RS19020	COG1335	isochorismatase
HV191_RS19025	COG0583	DNA-binding transcription factor activity
HV191_RS19030	COG0366	Alpha amylase catalytic
HV191_RS19045	COG5002	protein histidine kinase activity
HV191_RS19055	COG0420	3'-5' exonuclease activity
HV191_RS19060	COG0419	ATPase involved in DNA repair
HV191_RS19065	COG2814	Major facilitator Superfamily
HV191_RS19070	COG1940	carbohydrate kinase activity
HV191_RS19085	COG4126	flavin adenine dinucleotide binding
HV191_RS19105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV191_RS19110	COG3706	GGDEF domain
HV191_RS19120	COG1785	Belongs to the alkaline phosphatase family
HV191_RS19135	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV191_RS19155	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV191_RS19160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV191_RS19165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV191_RS19170	COG3468	outer membrane autotransporter barrel domain protein
HV191_RS19175	COG0113	porphobilinogen synthase activity
HV191_RS19180	COG2175	clavaminate synthase activity
HV191_RS19185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV191_RS19190	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV191_RS19195	COG4521	taurine ABC transporter
HV191_RS19210	COG2271	Major facilitator Superfamily
HV191_RS19215	COG1840	ABC-type Fe3 transport system, periplasmic component
HV191_RS19225	COG3842	ATPase activity
HV191_RS19230	COG2040	homocysteine
HV191_RS19235	COG0833	amino acid
HV191_RS19240	COG2814	Major facilitator Superfamily
HV191_RS19275	COG1414	Transcriptional regulator
HV191_RS19310	COG3210	domain, Protein
HV191_RS19325	COG1609	Transcriptional regulator
HV191_RS19345	COG3039	Transposase
HV191_RS19385	COG3344	reverse transcriptase
HV191_RS19395	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS19410	COG0840	transmembrane signaling receptor activity
HV191_RS19460	COG1294	oxidase, subunit
HV191_RS19485	COG3596	GTP binding
HV191_RS19495	COG2378	regulation of single-species biofilm formation
HV191_RS19505	COG2378	regulation of single-species biofilm formation
HV191_RS19525	COG2003	Belongs to the UPF0758 family
HV191_RS19560	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV191_RS19605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV191_RS19615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HV191_RS19640	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV191_RS19660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HV191_RS19665	COG1191	sigma factor activity
HV191_RS19690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HV191_RS19715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HV191_RS19720	COG4786	Flagellar basal body rod
HV191_RS19720	COG1256	bacterial-type flagellum assembly
HV191_RS19740	COG4786	Flagellar basal body rod
HV191_RS19745	COG4787	bacterial-type flagellum-dependent cell motility
HV191_RS19760	COG1558	bacterial-type flagellum-dependent cell motility
HV191_RS19795	COG0463	Glycosyl transferase, family 2
HV191_RS19795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HV191_RS19810	COG0110	maltose O-acetyltransferase activity
HV191_RS19815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HV191_RS19835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HV191_RS19845	COG1677	Flagellar hook-basal body complex protein FliE
HV191_RS19870	COG1987	bacterial-type flagellum assembly
HV191_RS19875	COG1684	flagellar biosynthetic protein fliR
HV191_RS19890	COG0791	NLP P60 protein
HV191_RS19895	COG3034	peptidoglycan biosynthetic process
HV191_RS19900	COG0121	glutamine amidotransferase
HV191_RS19910	COG1960	acyl-CoA dehydrogenase activity
HV191_RS19915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV191_RS19925	COG2200	EAL domain
HV191_RS19940	COG3539	Fimbrial protein
HV191_RS19945	COG3539	Fimbrial protein
HV191_RS19950	COG3121	Chaperone
HV191_RS19955	COG3188	usher protein
HV191_RS19965	COG3539	Fimbrial protein
HV191_RS19985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV191_RS19995	COG2226	methyltransferase
HV191_RS20005	COG0741	lytic transglycosylase activity
HV191_RS20005	COG1388	LysM domain
HV191_RS20010	COG2226	methyltransferase
HV191_RS20020	COG2814	Major facilitator Superfamily
HV191_RS20025	COG0583	DNA-binding transcription factor activity
HV191_RS20060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV191_RS20070	COG2011	ABC-type metal ion transport system permease component
HV191_RS20075	COG1464	Belongs to the NlpA lipoprotein family
HV191_RS20085	COG1720	tRNA m6t6A37 methyltransferase activity
HV191_RS20095	COG0791	NLP P60 protein
HV191_RS20100	COG3015	lipoprotein NlpE involved in copper resistance
HV191_RS20105	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV191_RS20120	COG4568	rho-dependent transcription termination
HV191_RS20130	COG0346	lactoylglutathione lyase activity
HV191_RS20170	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV191_RS20175	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV191_RS20190	COG0575	Belongs to the CDS family
HV191_RS20200	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV191_RS20245	COG3835	regulator
HV191_RS20270	COG2860	membrane
HV191_RS20295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV191_RS20300	COG1120	ATPase activity
HV191_RS20305	COG4774	siderophore transport
HV191_RS20310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV191_RS20315	COG1643	Atp-dependent helicase
HV191_RS20320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV191_RS20340	COG0617	tRNA 3'-terminal CCA addition
HV191_RS20345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV191_RS20365	COG0726	polysaccharide deacetylase
HV191_RS20370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS20375	COG0842	Transport permease protein
HV191_RS20380	COG1131	(ABC) transporter
HV191_RS20385	COG0288	reversible hydration of carbon dioxide
HV191_RS20390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HV191_RS20395	COG4993	Dehydrogenase
HV191_RS20430	COG3064	Membrane
HV191_RS20445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV191_RS20450	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV191_RS20455	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV191_RS20470	COG2211	Major facilitator Superfamily
HV191_RS20475	COG3940	Belongs to the glycosyl hydrolase 43 family
HV191_RS20480	COG3725	Membrane protein required for beta-lactamase induction
HV191_RS20495	COG4969	Belongs to the N-Me-Phe pilin family
HV191_RS20500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV191_RS20505	COG1459	type II secretion system
HV191_RS20515	COG0237	dephospho-CoA kinase activity
HV191_RS20530	COG0494	nUDIX hydrolase
HV191_RS20550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV191_RS20555	COG0849	cell division
HV191_RS20565	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV191_RS20580	COG0772	Belongs to the SEDS family
HV191_RS20585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HV191_RS20595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV191_RS20600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HV191_RS20605	COG0768	penicillin binding
HV191_RS20635	COG0028	Belongs to the TPP enzyme family
HV191_RS20680	COG2814	Major facilitator Superfamily
HV191_RS20700	COG1178	ABC-type Fe3 transport system permease component
HV191_RS20710	COG0586	Pfam SNARE associated Golgi protein
HV191_RS20730	COG0235	Class ii aldolase
HV191_RS20740	COG0417	DNA replication proofreading
HV191_RS20750	COG0564	pseudouridine synthase activity
HV191_RS20810	COG2271	Major facilitator Superfamily
HV191_RS20820	COG0644	oxidoreductase
HV191_RS20870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HV191_RS20875	COG0505	Belongs to the CarA family
HV191_RS20885	COG1609	Transcriptional regulator
HV191_RS20900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS20900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS20905	COG3715	PTS system
HV191_RS20910	COG3716	PTS system mannose fructose sorbose family IID component
HV191_RS20920	COG2140	Oxalate decarboxylase
HV191_RS20935	COG1047	Peptidyl-prolyl cis-trans
HV191_RS20950	COG0196	riboflavin kinase activity
HV191_RS20970	COG0583	DNA-binding transcription factor activity
HV191_RS20985	COG0443	Heat shock 70 kDa protein
HV191_RS20990	COG1584	GPR1 FUN34 yaaH family protein
HV191_RS21000	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV191_RS21010	COG1115	amino acid carrier protein
HV191_RS21020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV191_RS21030	COG0527	aspartate kinase activity
HV191_RS21030	COG0460	homoserine dehydrogenase
HV191_RS21040	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV191_RS21050	COG0745	RESPONSE REGULATOR receiver
HV191_RS21055	COG4452	Inner membrane protein CreD
HV191_RS21060	COG2205	protein histidine kinase activity
HV191_RS21065	COG0745	RESPONSE REGULATOR receiver
HV191_RS21070	COG3045	CreA protein
HV191_RS21075	COG3708	Transcriptional regulator
HV191_RS21075	COG2207	Transcriptional regulator
HV191_RS21095	COG0741	lytic transglycosylase activity
HV191_RS21100	COG0488	(ABC) transporter
HV191_RS21115	COG0560	Phosphoserine phosphatase
HV191_RS21120	COG3726	membrane protein affecting hemolysin expression
HV191_RS21150	COG1328	CTP reductase activity
HV191_RS21155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV191_RS21160	COG0084	hydrolase, TatD family'
HV191_RS21165	COG4667	esterase of the alpha-beta hydrolase superfamily
HV191_RS21170	COG5487	UPF0391 membrane protein
HV191_RS21175	COG2823	Periplasmic or secreted lipoprotein
HV191_RS21185	COG1011	Hydrolase
HV191_RS21190	COG0456	acetyltransferase
HV191_RS21195	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV191_RS21225	COG3706	GGDEF domain
HV191_RS21230	COG4114	ferric iron reductase
HV191_RS21235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV191_RS21240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV191_RS21245	COG2197	response regulator
HV191_RS21250	COG2197	response regulator
HV191_RS21255	COG2966	Psort location CytoplasmicMembrane, score
HV191_RS21270	COG1484	DNA-dependent DNA replication
HV191_RS21290	COG1063	alcohol dehydrogenase
HV191_RS21295	COG1802	Transcriptional regulator
HV191_RS21300	COG2271	Major facilitator Superfamily
HV191_RS21310	COG0840	transmembrane signaling receptor activity
HV191_RS21315	COG1966	Carbon starvation protein
HV191_RS21320	COG2879	small protein
HV191_RS21325	COG0523	cobalamin synthesis protein
HV191_RS21355	COG1715	Restriction endonuclease
HV191_RS21390	COG1566	PFAM secretion protein HlyD family protein
HV191_RS21400	COG5457	Domain of unknown function (DUF1127)
HV191_RS21405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV191_RS21410	COG5464	transposase or invertase
HV191_RS21410	COG5464	transposase or invertase
HV191_RS21415	COG2207	Transcriptional regulator
HV191_RS21415	COG1917	Cupin 2, conserved barrel domain protein
HV191_RS21430	COG0626	cystathionine gamma-synthase activity
HV191_RS21435	COG1301	dicarboxylic acid transport
HV191_RS21440	COG0583	DNA-binding transcription factor activity
HV191_RS21445	COG2733	membrane
HV191_RS21450	COG0477	Major facilitator Superfamily
HV191_RS21460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV191_RS21470	COG2186	Transcriptional regulator
HV191_RS21475	COG0246	Mannitol dehydrogenase
HV191_RS21485	COG2610	gluconate transmembrane transporter activity
HV191_RS21490	COG1556	Lactate utilization protein
HV191_RS21495	COG1139	Iron-sulfur cluster binding protein
HV191_RS21500	COG0247	lactate metabolic process
HV191_RS21505	COG1620	l-lactate permease
HV191_RS21590	COG1196	nuclear chromosome segregation
HV191_RS21595	COG0582	viral genome integration into host DNA
HV191_RS21605	COG1064	alcohol dehydrogenase
HV191_RS21610	COG3265	gluconokinase activity
HV191_RS21615	COG1063	alcohol dehydrogenase
HV191_RS21620	COG1028	Short-chain dehydrogenase reductase Sdr
HV191_RS21625	COG2610	gluconate transmembrane transporter activity
HV191_RS21630	COG1609	Transcriptional regulator
HV191_RS21635	COG0433	COG0433 Predicted ATPase
HV191_RS21640	COG0795	lipopolysaccharide-transporting ATPase activity
HV191_RS21645	COG0795	lipopolysaccharide-transporting ATPase activity
HV191_RS21655	COG2927	DNA polymerase III (CHI subunit)
HV191_RS21660	COG0525	valine-tRNA ligase activity
HV191_RS21695	COG2731	YhcH YjgK YiaL family protein
HV191_RS21710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HV191_RS21715	COG1288	antiporter activity
HV191_RS21720	COG1438	arginine binding
HV191_RS21770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS21770	COG1263	PTS System
HV191_RS21775	COG0366	Alpha amylase catalytic
HV191_RS21795	COG3501	Rhs element vgr protein
HV191_RS21800	COG2026	Addiction module toxin, RelE StbE family
HV191_RS21880	COG3711	transcriptional antiterminator
HV191_RS21880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS21895	COG3964	amidohydrolase
HV191_RS21930	COG0312	modulator of DNA gyrase
HV191_RS21940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV191_RS21950	COG1486	melibiose metabolic process
HV191_RS21955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV191_RS21955	COG0517	IMP dehydrogenase activity
HV191_RS21960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV191_RS21970	COG0840	transmembrane signaling receptor activity
HV191_RS21975	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS21980	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS21985	COG1129	ABC transporter
HV191_RS21990	COG1879	ABC-type sugar transport system periplasmic component
HV191_RS22000	COG3391	amine dehydrogenase activity
HV191_RS22005	COG4771	TonB-dependent receptor
HV191_RS22010	COG2105	PFAM AIG2 family protein
HV191_RS22015	COG2911	Protein conserved in bacteria
HV191_RS22020	COG0729	surface antigen
HV191_RS22030	COG1253	flavin adenine dinucleotide binding
HV191_RS22040	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV191_RS22045	COG1218	3'(2'),5'-bisphosphate nucleotidase
HV191_RS22055	COG1733	regulation of RNA biosynthetic process
HV191_RS22060	COG0702	epimerase
HV191_RS22070	COG0697	spore germination
HV191_RS22075	COG0840	transmembrane signaling receptor activity
HV191_RS22085	COG1113	amino acid transport
HV191_RS22090	COG0545	Peptidyl-prolyl cis-trans isomerase
HV191_RS22095	COG3061	Opacity-associated protein A
HV191_RS22110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV191_RS22125	COG0730	response to heat
HV191_RS22175	COG1073	alpha beta
HV191_RS22180	COG3650	response to hydrogen peroxide
HV191_RS22190	COG1960	acyl-CoA dehydrogenase activity
HV191_RS22195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV191_RS22200	COG0557	exoribonuclease II activity
HV191_RS22215	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV191_RS22220	COG0330	HflC and HflK could
HV191_RS22225	COG0330	HflC and HflK could
HV191_RS22230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV191_RS22235	COG1923	regulation of RNA biosynthetic process
HV191_RS22250	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV191_RS22255	COG0802	atpase or kinase
HV191_RS22260	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV191_RS22260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV191_RS22265	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV191_RS22300	COG1511	domain protein
HV191_RS22300	COG3264	Mechanosensitive ion channel
HV191_RS22325	COG1053	succinate dehydrogenase
HV191_RS22330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV191_RS22385	COG1509	lysine 2,3-aminomutase activity
HV191_RS22410	COG0531	amino acid
HV191_RS22415	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV191_RS22420	COG1027	Aspartate ammonia-lyase
HV191_RS22425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV191_RS22440	COG1309	transcriptional regulator
HV191_RS22450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HV191_RS22460	COG0210	DNA helicase
HV191_RS22535	COG2223	nitrite transmembrane transporter activity
HV191_RS22545	COG1609	Transcriptional regulator
HV191_RS22750	COG0629	single-stranded DNA binding
HV191_RS22760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV191_RS22840	COG3039	Transposase
HV191_RS22860	COG4974	Belongs to the 'phage' integrase family
HV191_RS22905	COG3596	GTP binding
HV191_RS22995	COG3290	protein histidine kinase activity
HV191_RS23000	COG4565	transcriptional regulatory protein
HV191_RS23010	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV191_RS23015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS23015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV191_RS23020	COG3647	Membrane
HV191_RS23030	COG2211	Major facilitator Superfamily
HV191_RS23035	COG1486	melibiose metabolic process
HV191_RS23040	COG2169	Transcriptional regulator
HV191_RS23045	COG1982	Orn Lys Arg decarboxylase major
HV191_RS23050	COG2207	Transcriptional regulator
HV191_RS23055	COG0531	amino acid
HV191_RS23100	COG2824	Alkylphosphonate utilization operon protein PhnA
HV191_RS23105	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV191_RS23110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HV191_RS23115	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV191_RS23120	COG3639	organic phosphonate transmembrane transporter activity
HV191_RS23125	COG2188	Transcriptional regulator
HV191_RS23130	COG3624	Phosphonate C-P lyase system protein PhnG
HV191_RS23135	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV191_RS23140	COG3626	phosphonate metabolism
HV191_RS23145	COG3627	carbon phosphorus lyase activity
HV191_RS23150	COG4107	phosphonate C-P lyase system protein PhnK
HV191_RS23155	COG4778	phosphonate C-P lyase system protein PhnL
HV191_RS23160	COG3454	Phosphonate metabolism
HV191_RS23165	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV191_RS23170	COG0456	acetyltransferase
HV191_RS23175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV191_RS23195	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS23205	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS23255	COG0745	RESPONSE REGULATOR receiver
HV191_RS23265	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV191_RS23270	COG1301	dicarboxylic acid transport
HV191_RS23275	COG4235	cytochrome complex assembly
HV191_RS23280	COG3088	subunit of a heme lyase
HV191_RS23300	COG3301	Polysulphide reductase, NrfD
HV191_RS23305	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS23310	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HV191_RS23320	COG2801	Transposase and inactivated derivatives
HV191_RS23360	COG1127	ABC transporter
HV191_RS23365	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV191_RS23380	COG2841	Protein conserved in bacteria
HV191_RS23395	COG0753	catalase activity
HV191_RS23445	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HV191_RS23460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV191_RS23470	COG0583	DNA-binding transcription factor activity
HV191_RS23480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV191_RS23485	COG0625	glutathione transferase activity
HV191_RS23520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV191_RS23540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV191_RS23545	COG5433	transposase activity
HV191_RS23555	COG0456	acetyltransferase
HV191_RS23605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV191_RS23880	COG0629	single-stranded DNA binding
HV191_RS23960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV191_RS24015	COG0058	SHG alpha-glucan phosphorylase activity
HV191_RS24020	COG0033	Phosphoglucomutase
HV191_RS24030	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS24095	COG2801	Transposase and inactivated derivatives
HV191_RS24110	COG3162	membrane
HV191_RS24120	COG1346	cytolysis
HV191_RS24125	COG1380	Effector of murein hydrolase LrgA
HV191_RS24130	COG0583	DNA-binding transcription factor activity
HV191_RS24135	COG0025	NhaP-type Na H and K H
HV191_RS24140	COG2252	PERMEase
HV191_RS24145	COG0789	Transcriptional regulator
HV191_RS24155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV191_RS24165	COG0629	single-stranded DNA binding
HV191_RS24170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HV191_RS24175	COG2315	Protein conserved in bacteria
HV191_RS24180	COG3700	Belongs to the class B bacterial acid phosphatase family
HV191_RS24185	COG1448	Aminotransferase
HV191_RS24195	COG0305	Participates in initiation and elongation during chromosome replication
HV191_RS24210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV191_RS24220	COG0735	belongs to the Fur family
HV191_RS24225	COG3237	CsbD-like
HV191_RS24230	COG0534	Mate efflux family protein
HV191_RS24240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV191_RS24275	COG2182	Extracellular solute-binding protein
HV191_RS24290	COG3223	Belongs to the PsiE family
HV191_RS24295	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV191_RS24300	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV191_RS24325	COG0527	aspartate kinase activity
HV191_RS24340	COG1187	pseudouridine synthase activity
HV191_RS24345	COG4977	sequence-specific DNA binding
HV191_RS24365	COG1410	methionine synthase
HV191_RS24365	COG0646	methionine synthase
HV191_RS24385	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV191_RS24420	COG0151	Belongs to the GarS family
HV191_RS24430	COG4191	Histidine kinase
HV191_RS24485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV191_RS24490	COG2104	thiamine diphosphate biosynthetic process
HV191_RS24505	COG1278	Cold shock
HV191_RS24515	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV191_RS24550	COG0250	Participates in transcription elongation, termination and antitermination
HV191_RS24595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV191_RS24655	COG0583	DNA-binding transcription factor activity
HV191_RS24660	COG3979	chitinase
HV191_RS24695	COG2207	Transcriptional regulator
HV191_RS24700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS24705	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV191_RS24710	COG1882	Formate acetyltransferase
HV191_RS24715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS24720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS24725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS24725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS24725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV191_RS24735	COG0371	Dehydrogenase
HV191_RS24745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HV191_RS24750	COG0583	DNA-binding transcription factor activity
HV191_RS24760	COG0737	Belongs to the 5'-nucleotidase family
HV191_RS24770	COG0527	aspartate kinase activity
HV191_RS24770	COG0460	homoserine dehydrogenase
HV191_RS24775	COG0626	cystathionine gamma-synthase activity
HV191_RS24785	COG2211	Major facilitator Superfamily
HV191_RS24800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV191_RS24805	COG1609	Transcriptional regulator
HV191_RS24810	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV191_RS24825	COG1575	Belongs to the MenA family. Type 1 subfamily
HV191_RS24840	COG0582	viral genome integration into host DNA
HV191_RS24860	COG3074	FtsZ-dependent cytokinesis
HV191_RS24865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV191_RS24875	COG1494	fructose-1,6-bisphosphatase
HV191_RS24885	COG3152	Membrane
HV191_RS24910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HV191_RS24970	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HV191_RS25060	COG4695	Portal protein
HV191_RS25085	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV191_RS25120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HV191_RS25125	COG3678	ATP-independent chaperone mediated protein folding
HV191_RS25130	COG0745	RESPONSE REGULATOR receiver
HV191_RS25135	COG2205	protein histidine kinase activity
HV191_RS25140	COG2271	Major facilitator Superfamily
HV191_RS25145	COG1082	Xylose isomerase domain protein TIM barrel
HV191_RS25150	COG2188	Transcriptional regulator
HV191_RS25155	COG2258	MOSC domain
HV191_RS25160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV191_RS25205	COG1454	alcohol dehydrogenase
HV191_RS25220	COG3039	Transposase
HV191_RS25230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV191_RS25240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS25245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS25245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV191_RS25250	COG1363	Peptidase, m42
HV191_RS25255	COG3711	transcriptional antiterminator
HV191_RS25255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV191_RS25275	COG0437	4 iron, 4 sulfur cluster binding
HV191_RS25280	COG2864	formate dehydrogenase
HV191_RS25295	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV191_RS25300	COG0657	acetylesterase activity
HV191_RS25305	COG3609	addiction module antidote protein, CC2985 family
HV191_RS25315	COG0456	acetyltransferase
HV191_RS25320	COG1490	D-aminoacyl-tRNA deacylase activity
HV191_RS25345	COG1349	DNA-binding transcription factor activity
HV191_RS25350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS25360	COG3684	Belongs to the aldolase LacD family
HV191_RS25370	COG2017	converts alpha-aldose to the beta-anomer
HV191_RS25375	COG1501	Belongs to the glycosyl hydrolase 31 family
HV191_RS25405	COG3852	Histidine kinase
HV191_RS25410	COG2204	response regulator
HV191_RS25420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV191_RS25445	COG0204	Acyl-transferase
HV191_RS25460	COG3084	Protein conserved in bacteria
HV191_RS25465	COG0746	molybdenum cofactor guanylyltransferase activity
HV191_RS25470	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV191_RS25510	COG1739	Uncharacterized protein family UPF0029
HV191_RS25530	COG1609	Transcriptional regulator
HV191_RS25535	COG1940	carbohydrate kinase activity
HV191_RS25545	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV191_RS25560	COG0805	protein transport
HV191_RS25605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV191_RS25610	COG0583	DNA-binding transcription factor activity
HV191_RS25615	COG0697	spore germination
HV191_RS25620	COG0561	phosphatase activity
HV191_RS25625	COG2267	carboxylic ester hydrolase activity
HV191_RS25630	COG1280	lysine exporter protein (LysE YggA)
HV191_RS25635	COG1280	lysine exporter protein (LysE YggA)
HV191_RS25670	COG1011	Hydrolase
HV191_RS25715	COG2959	enzyme of heme biosynthesis
HV191_RS25720	COG3071	HemY protein
HV191_RS25765	COG2244	polysaccharide biosynthetic process
HV191_RS25770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV191_RS25775	COG0456	acetyltransferase
HV191_RS25780	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HV191_RS25785	COG1088	dTDP-glucose 4,6-dehydratase activity
HV191_RS25790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV191_RS25805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV191_RS25810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV191_RS25820	COG3118	belongs to the thioredoxin family
HV191_RS25840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV191_RS25860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV191_RS25870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV191_RS25875	COG3978	acetolactate synthase activity
HV191_RS25895	COG3085	chromosome segregation
HV191_RS25935	COG2186	Transcriptional regulator
HV191_RS25940	COG0477	Major facilitator Superfamily
HV191_RS25945	COG1609	Transcriptional regulator
HV191_RS25950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV191_RS25955	COG1879	ABC-type sugar transport system periplasmic component
HV191_RS25960	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS25970	COG1869	D-ribose catabolic process
HV191_RS25995	COG1522	sequence-specific DNA binding
HV191_RS26000	COG0716	FMN binding
HV191_RS26015	COG3312	ion transport
HV191_RS26040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HV191_RS26050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HV191_RS26055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HV191_RS26070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV191_RS26075	COG0573	inorganic phosphate transmembrane transporter activity
HV191_RS26080	COG0581	inorganic phosphate transmembrane transporter activity
HV191_RS26090	COG0704	Plays a role in the regulation of phosphate uptake
HV191_RS26095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV191_RS26100	COG2252	PERMEase
HV191_RS26105	COG0431	NADPH-dependent FMN reductase
HV191_RS26110	COG2091	lysine biosynthetic process via aminoadipic acid
HV191_RS26145	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HV191_RS26165	COG0235	Class ii aldolase
HV191_RS26170	COG1349	DNA-binding transcription factor activity
HV191_RS26180	COG1129	ABC transporter
HV191_RS26185	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS26190	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV191_RS26195	COG3623	hexulose-6-phosphate isomerase
HV191_RS26200	COG1070	Carbohydrate kinase
HV191_RS26210	COG3039	Transposase
HV191_RS26215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV191_RS26220	COG0698	ribose 5-phosphate isomerase
HV191_RS26225	COG2190	(PTS) system
HV191_RS26225	COG1263	PTS System
HV191_RS26225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV191_RS26230	COG1737	Transcriptional regulator
HV191_RS26280	COG1528	Iron-storage protein
HV191_RS26290	COG3039	Transposase
HV191_RS26315	COG1136	(ABC) transporter
HV191_RS26330	COG1309	transcriptional regulator
HV191_RS26360	COG0589	response to stress
HV191_RS26365	COG0659	secondary active sulfate transmembrane transporter activity
HV191_RS26400	COG3039	Transposase
HV191_RS26410	COG3344	reverse transcriptase
HV191_RS26420	COG2826	transposase and inactivated derivatives, IS30 family
HV191_RS26450	COG1121	(ABC) transporter
HV191_RS26485	COG2135	peptidase activity
HV191_RS26540	COG0629	single-stranded DNA binding
HV191_RS26700	COG3436	PFAM IS66 Orf2 family protein
HV191_RS26705	COG2433	Pfam Transposase IS66