locus-tag	class	description
HV311_RS00010	COG0592	DNA-directed DNA polymerase activity
HV311_RS00025	COG0561	phosphatase activity
HV311_RS00035	COG0823	Involved in the tonB-independent uptake of proteins
HV311_RS00040	COG5645	(Lipo)protein
HV311_RS00065	COG2149	membrane
HV311_RS00075	COG0641	radical SAM
HV311_RS00085	COG2610	gluconate transmembrane transporter activity
HV311_RS00090	COG0583	DNA-binding transcription factor activity
HV311_RS00100	COG2814	Major facilitator Superfamily
HV311_RS00120	COG0028	Belongs to the TPP enzyme family
HV311_RS00125	COG0440	acetolactate synthase activity
HV311_RS00130	COG1349	DNA-binding transcription factor activity
HV311_RS00145	COG0738	Major facilitator superfamily
HV311_RS00155	COG2197	response regulator
HV311_RS00185	COG3620	sequence-specific DNA binding
HV311_RS00195	COG2723	6-phospho-beta-galactosidase activity
HV311_RS00210	COG1464	Belongs to the NlpA lipoprotein family
HV311_RS00215	COG0697	spore germination
HV311_RS00225	COG0604	alcohol dehydrogenase
HV311_RS00230	COG0583	DNA-binding transcription factor activity
HV311_RS00250	COG2771	luxR family
HV311_RS00270	COG3210	domain, Protein
HV311_RS00270	COG3468	outer membrane autotransporter barrel domain protein
HV311_RS00330	COG2003	Belongs to the UPF0758 family
HV311_RS00355	COG2378	regulation of single-species biofilm formation
HV311_RS00365	COG3596	GTP binding
HV311_RS00390	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HV311_RS00415	COG0582	viral genome integration into host DNA
HV311_RS00425	COG2211	Major facilitator Superfamily
HV311_RS00430	COG1501	Belongs to the glycosyl hydrolase 31 family
HV311_RS00435	COG3711	transcriptional antiterminator
HV311_RS00440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS00440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS00440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS00445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS00450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS00450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS00460	COG0191	fructose-bisphosphate aldolase activity
HV311_RS00470	COG2982	Protein involved in outer membrane biogenesis
HV311_RS00475	COG2233	PERMEase
HV311_RS00480	COG0786	glutamate:sodium symporter activity
HV311_RS00485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HV311_RS00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV311_RS00495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV311_RS00515	COG2860	membrane
HV311_RS00530	COG1561	YicC-like family, N-terminal region
HV311_RS00555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HV311_RS00570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HV311_RS00585	COG1519	Transferase
HV311_RS00590	COG0859	PFAM glycosyl transferase family 9
HV311_RS00595	COG0438	transferase activity, transferring glycosyl groups
HV311_RS00600	COG0515	serine threonine protein kinase
HV311_RS00625	COG0859	PFAM glycosyl transferase family 9
HV311_RS00630	COG0859	PFAM glycosyl transferase family 9
HV311_RS00650	COG0156	8-amino-7-oxononanoate synthase activity
HV311_RS00665	COG1216	Glycosyl transferase, family 2
HV311_RS00670	COG2861	carbohydrate metabolic process
HV311_RS00675	COG4942	peptidase
HV311_RS00685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV311_RS00690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HV311_RS00710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HV311_RS00715	COG2271	Major facilitator Superfamily
HV311_RS00725	COG2186	Transcriptional regulator
HV311_RS00745	COG3722	fumarate hydratase activity
HV311_RS00755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS00755	COG2213	PTS system mannitol-specific
HV311_RS00765	COG1566	PFAM secretion protein HlyD family protein
HV311_RS00770	COG0625	glutathione transferase activity
HV311_RS00780	COG3276	selenocysteine insertion sequence binding
HV311_RS00785	COG1454	alcohol dehydrogenase
HV311_RS00790	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS00800	COG1566	PFAM secretion protein HlyD family protein
HV311_RS00805	COG0583	DNA-binding transcription factor activity
HV311_RS00810	COG3713	MltA-interacting MipA family protein
HV311_RS00820	COG0235	Class ii aldolase
HV311_RS00825	COG3623	hexulose-6-phosphate isomerase
HV311_RS00830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HV311_RS00835	COG1070	Carbohydrate kinase
HV311_RS00840	COG2271	Major facilitator Superfamily
HV311_RS00850	COG2731	YhcH YjgK YiaL family protein
HV311_RS00860	COG1414	Transcriptional regulator
HV311_RS00865	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS00870	COG3977	Valine--pyruvate aminotransferase
HV311_RS00875	COG0366	Alpha amylase catalytic
HV311_RS00880	COG2992	FlgJ-related protein
HV311_RS00885	COG1609	Transcriptional regulator
HV311_RS00885	COG2207	Transcriptional regulator
HV311_RS00890	COG4214	carbohydrate transport
HV311_RS00900	COG4213	ABC transporter substrate-binding protein
HV311_RS00910	COG1070	Carbohydrate kinase
HV311_RS00915	COG4682	membrane
HV311_RS00920	COG4682	membrane
HV311_RS00925	COG3274	enterobacterial common antigen metabolic process
HV311_RS00950	COG1278	Cold shock
HV311_RS00955	COG2944	sequence-specific DNA binding
HV311_RS00970	COG2814	Major facilitator Superfamily
HV311_RS00975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS00985	COG1609	Transcriptional regulator
HV311_RS00990	COG2885	chlorophyll binding
HV311_RS00995	COG0243	molybdopterin cofactor binding
HV311_RS01000	COG0456	acetyltransferase
HV311_RS01005	COG2818	Glycosylase
HV311_RS01010	COG5571	outer membrane autotransporter
HV311_RS01020	COG2223	nitrite transmembrane transporter activity
HV311_RS01045	COG0747	negative chemotaxis
HV311_RS01050	COG0601	transmembrane transport
HV311_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV311_RS01060	COG0444	Belongs to the ABC transporter superfamily
HV311_RS01065	COG4608	Belongs to the ABC transporter superfamily
HV311_RS01070	COG2204	response regulator
HV311_RS01075	COG0814	amino acid
HV311_RS01080	COG0626	cystathionine gamma-synthase activity
HV311_RS01090	COG2199	diguanylate cyclase activity
HV311_RS01090	COG2200	EAL domain
HV311_RS01105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS01110	COG2200	EAL domain
HV311_RS01115	COG2982	Protein involved in outer membrane biogenesis
HV311_RS01120	COG0477	Major facilitator Superfamily
HV311_RS01125	COG1295	ribonuclease BN
HV311_RS01130	COG0583	DNA-binding transcription factor activity
HV311_RS01140	COG2197	response regulator
HV311_RS01150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV311_RS01165	COG1858	cytochrome C peroxidase
HV311_RS01175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV311_RS01180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HV311_RS01185	COG0339	signal peptide processing
HV311_RS01200	COG1959	2 iron, 2 sulfur cluster binding
HV311_RS01210	COG0589	response to stress
HV311_RS01220	COG0306	phosphate transporter
HV311_RS01225	COG2081	HI0933 family
HV311_RS01230	COG2239	Acts as a magnesium transporter
HV311_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS01240	COG0842	Transport permease protein
HV311_RS01240	COG1129	ABC transporter
HV311_RS01245	COG0842	Transport permease protein
HV311_RS01260	COG3479	Phenolic acid decarboxylase
HV311_RS01265	COG2091	lysine biosynthetic process via aminoadipic acid
HV311_RS01270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV311_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS01285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV311_RS01310	COG1216	Glycosyl transferase, family 2
HV311_RS01330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HV311_RS01360	COG0628	permease
HV311_RS01365	COG0477	Major facilitator Superfamily
HV311_RS01375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HV311_RS01390	COG3714	YhhN family
HV311_RS01400	COG3776	membrane
HV311_RS01405	COG0742	ribosomal rna small subunit methyltransferase
HV311_RS01410	COG0552	protein localization to endoplasmic reticulum
HV311_RS01415	COG2884	Cell division ATP-binding protein ftsE
HV311_RS01420	COG2177	Part of the ABC transporter FtsEX involved in
HV311_RS01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV311_RS01435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV311_RS01460	COG0683	leucine binding
HV311_RS01470	COG0683	leucine binding
HV311_RS01480	COG4177	L-phenylalanine transmembrane transporter activity
HV311_RS01485	COG0411	ABC transporter
HV311_RS01490	COG0410	ABC transporter
HV311_RS01520	COG0584	glycerophosphoryl diester phosphodiesterase
HV311_RS01530	COG0405	Gamma-glutamyltransferase
HV311_RS01540	COG1247	-acetyltransferase
HV311_RS01545	COG0673	inositol 2-dehydrogenase activity
HV311_RS01550	COG1741	Belongs to the pirin family
HV311_RS01555	COG1609	Transcriptional regulator
HV311_RS01560	COG3265	gluconokinase activity
HV311_RS01565	COG2610	gluconate transmembrane transporter activity
HV311_RS01575	COG2095	MarC family integral membrane protein
HV311_RS01580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV311_RS01605	COG0058	SHG alpha-glucan phosphorylase activity
HV311_RS01610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV311_RS01625	COG1349	DNA-binding transcription factor activity
HV311_RS01635	COG0058	SHG alpha-glucan phosphorylase activity
HV311_RS01640	COG1640	4-alpha-glucanotransferase
HV311_RS01645	COG2610	gluconate transmembrane transporter activity
HV311_RS01655	COG1040	competence protein
HV311_RS01665	COG5464	transposase or invertase
HV311_RS01680	COG1918	ferrous iron import across plasma membrane
HV311_RS01685	COG2183	response to ionizing radiation
HV311_RS01690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV311_RS01710	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HV311_RS01720	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HV311_RS01725	COG1011	Hydrolase
HV311_RS01735	COG0494	nUDIX hydrolase
HV311_RS01740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HV311_RS01745	COG4972	Pilus assembly protein
HV311_RS01765	COG4796	Type ii and iii secretion system protein
HV311_RS01780	COG3266	domain, Protein
HV311_RS01785	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HV311_RS01790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HV311_RS01800	COG0180	Tryptophanyl-tRNA synthetase
HV311_RS01820	COG2146	nitrite reductase [NAD(P)H] activity
HV311_RS01825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HV311_RS01850	COG0512	Glutamine amidotransferase of anthranilate synthase
HV311_RS01855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HV311_RS01860	COG1289	transmembrane transporter activity
HV311_RS01870	COG1765	OsmC-like protein
HV311_RS01875	COG3954	Phosphoribulokinase
HV311_RS01885	COG0429	hydrolase of the alpha beta-hydrolase fold
HV311_RS01890	COG0488	(ABC) transporter
HV311_RS01905	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HV311_RS01910	COG1047	Peptidyl-prolyl cis-trans
HV311_RS01920	COG0545	Peptidyl-prolyl cis-trans isomerase
HV311_RS01925	COG2964	Protein conserved in bacteria
HV311_RS01985	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HV311_RS01990	COG3156	type II secretion system protein K
HV311_RS01995	COG4795	General secretion pathway protein
HV311_RS02000	COG2165	general secretion pathway protein
HV311_RS02005	COG2165	general secretion pathway protein
HV311_RS02010	COG2165	general secretion pathway protein
HV311_RS02015	COG1459	type II secretion system
HV311_RS02020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV311_RS02025	COG1450	Type ii and iii secretion system protein
HV311_RS02045	COG0051	transcription antitermination factor activity, RNA binding
HV311_RS02055	COG0088	Forms part of the polypeptide exit tunnel
HV311_RS02070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HV311_RS02145	COG0200	Binds to the 23S rRNA
HV311_RS02150	COG0201	protein transport
HV311_RS02165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HV311_RS02190	COG0789	Transcriptional regulator
HV311_RS02195	COG3036	rescue of stalled ribosome
HV311_RS02205	COG0569	domain protein
HV311_RS02225	COG0758	DNA mediated transformation
HV311_RS02235	COG0551	DNA topoisomerase type I activity
HV311_RS02255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV311_RS02295	COG1126	abc transporter atp-binding protein
HV311_RS02300	COG0765	amino acid transport
HV311_RS02305	COG4597	amino acid ABC transporter
HV311_RS02310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS02320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV311_RS02325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS02330	COG1309	transcriptional regulator
HV311_RS02340	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HV311_RS02360	COG4145	pantothenate transmembrane transporter activity
HV311_RS02365	COG3924	membrane
HV311_RS02370	COG0439	Biotin carboxylase
HV311_RS02375	COG0511	ligase activity, forming carbon-carbon bonds
HV311_RS02390	COG0604	alcohol dehydrogenase
HV311_RS02395	COG2199	diguanylate cyclase activity
HV311_RS02395	COG2200	EAL domain
HV311_RS02400	COG1077	Cell shape determining protein MreB Mrl
HV311_RS02405	COG1792	Involved in formation and maintenance of cell shape
HV311_RS02410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HV311_RS02425	COG3164	Protein of unknown function
HV311_RS02430	COG0312	modulator of DNA gyrase
HV311_RS02435	COG0583	DNA-binding transcription factor activity
HV311_RS02455	COG2732	(Barnase) inhibitor
HV311_RS02475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV311_RS02480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HV311_RS02485	COG3105	Protein conserved in bacteria
HV311_RS02490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HV311_RS02505	COG0625	glutathione transferase activity
HV311_RS02510	COG2969	positive regulation of protein catabolic process
HV311_RS02515	COG3069	C4-dicarboxylate transmembrane transporter activity
HV311_RS02545	COG2731	YhcH YjgK YiaL family protein
HV311_RS02550	COG0402	S-adenosylhomocysteine deaminase activity
HV311_RS02555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HV311_RS02560	COG0493	'glutamate synthase
HV311_RS02565	COG0069	glutamate synthase activity
HV311_RS02565	COG0070	glutamate synthase
HV311_RS02565	COG0067	glutamate synthase
HV311_RS02570	COG1242	4 iron, 4 sulfur cluster binding
HV311_RS02575	COG0784	Response regulator, receiver
HV311_RS02575	COG2198	Histidine kinase
HV311_RS02575	COG5002	protein histidine kinase activity
HV311_RS02580	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
HV311_RS02590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS02605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV311_RS02615	COG1137	ATPase activity
HV311_RS02620	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HV311_RS02625	COG3117	lipopolysaccharide transmembrane transporter activity
HV311_RS02630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HV311_RS02635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV311_RS02635	COG0517	IMP dehydrogenase activity
HV311_RS02640	COG0530	calcium, potassium:sodium antiporter activity
HV311_RS02645	COG1127	ABC transporter
HV311_RS02650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV311_RS02655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV311_RS02660	COG2854	intermembrane phospholipid transfer
HV311_RS02665	COG3113	response to antibiotic
HV311_RS02670	COG5007	Belongs to the BolA IbaG family
HV311_RS02680	COG3423	Transcriptional regulator
HV311_RS02685	COG0142	geranyltranstransferase activity
HV311_RS02690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HV311_RS02695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HV311_RS02700	COG0697	spore germination
HV311_RS02710	COG2027	D-alanyl-D-alanine carboxypeptidase
HV311_RS02720	COG1534	Rna-binding protein
HV311_RS02730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HV311_RS02735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HV311_RS02745	COG3069	C4-dicarboxylate transmembrane transporter activity
HV311_RS02750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV311_RS02755	COG0583	DNA-binding transcription factor activity
HV311_RS02760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HV311_RS02785	COG0195	Participates in both transcription termination and antitermination
HV311_RS02795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HV311_RS02825	COG0513	Belongs to the DEAD box helicase family
HV311_RS02830	COG0814	amino acid
HV311_RS02835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV311_RS02840	COG0826	peptidase U32
HV311_RS02845	COG0826	peptidase U32
HV311_RS02850	COG3154	lipid carrier protein
HV311_RS02855	COG3153	acetyltransferase
HV311_RS02870	COG0702	epimerase
HV311_RS02875	COG2823	Periplasmic or secreted lipoprotein
HV311_RS02890	COG3107	peptidoglycan biosynthetic process
HV311_RS02895	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HV311_RS02910	COG1063	alcohol dehydrogenase
HV311_RS02915	COG3775	system Galactitol-specific IIC component
HV311_RS02920	COG3414	Phosphotransferase system galactitol-specific IIB component
HV311_RS02925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS02940	COG2721	sulfolactate sulfo-lyase activity
HV311_RS02945	COG2271	Major facilitator Superfamily
HV311_RS02955	COG2084	Dehydrogenase
HV311_RS02960	COG1929	Belongs to the glycerate kinase type-1 family
HV311_RS02970	COG0583	DNA-binding transcription factor activity
HV311_RS02980	COG3039	Transposase
HV311_RS03000	COG1882	Formate acetyltransferase
HV311_RS03005	COG0251	oxidation-reduction process
HV311_RS03010	COG1760	l-serine dehydratase
HV311_RS03015	COG0814	amino acid
HV311_RS03030	COG1741	Belongs to the pirin family
HV311_RS03035	COG0583	DNA-binding transcription factor activity
HV311_RS03040	COG3152	Membrane
HV311_RS03045	COG0435	Glutathione S-transferase
HV311_RS03050	COG2259	Doxx family
HV311_RS03060	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
HV311_RS03065	COG4575	ribosome binding
HV311_RS03070	COG1422	Protein of unknown function (DUF1090)
HV311_RS03080	COG0586	Pfam SNARE associated Golgi protein
HV311_RS03085	COG2186	Transcriptional regulator
HV311_RS03090	COG2271	Major facilitator Superfamily
HV311_RS03100	COG2721	sulfolactate sulfo-lyase activity
HV311_RS03120	COG0673	inositol 2-dehydrogenase activity
HV311_RS03125	COG1451	nucleotide metabolic process
HV311_RS03135	COG1902	pentaerythritol trinitrate reductase activity
HV311_RS03135	COG0446	pyridine nucleotide-disulphide oxidoreductase
HV311_RS03150	COG1609	Transcriptional regulator
HV311_RS03160	COG1175	transmembrane transport
HV311_RS03165	COG0395	ABC-type sugar transport system, permease component
HV311_RS03170	COG0366	Alpha amylase catalytic
HV311_RS03175	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HV311_RS03180	COG0531	amino acid
HV311_RS03185	COG2731	YhcH YjgK YiaL family protein
HV311_RS03190	COG3250	beta-galactosidase activity
HV311_RS03195	COG1609	Transcriptional regulator
HV311_RS03200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HV311_RS03210	COG0840	transmembrane signaling receptor activity
HV311_RS03215	COG1695	Transcriptional regulator
HV311_RS03220	COG2375	cellular response to nickel ion
HV311_RS03230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV311_RS03300	COG0582	viral genome integration into host DNA
HV311_RS03335	COG0358	DNA primase activity
HV311_RS03340	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HV311_RS03345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HV311_RS03350	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV311_RS03360	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HV311_RS03390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS03395	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS03410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV311_RS03425	COG4991	sh3 domain protein
HV311_RS03430	COG3025	triphosphatase activity
HV311_RS03485	COG3384	dioxygenase
HV311_RS03490	COG0754	glutathionylspermidine amidase activity
HV311_RS03505	COG0494	nUDIX hydrolase
HV311_RS03510	COG3151	Protein conserved in bacteria
HV311_RS03515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HV311_RS03520	COG3150	esterase
HV311_RS03525	COG0187	DNA topoisomerase II activity
HV311_RS03530	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HV311_RS03535	COG2249	NAD(P)H dehydrogenase (quinone) activity
HV311_RS03550	COG3111	PFAM Bacterial OB fold (BOF) protein
HV311_RS03570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HV311_RS03585	COG0656	L-ascorbic acid biosynthetic process
HV311_RS03590	COG1979	alcohol dehydrogenase
HV311_RS03595	COG2207	Transcriptional regulator
HV311_RS03600	COG0586	Pfam SNARE associated Golgi protein
HV311_RS03605	COG0626	cystathionine gamma-synthase activity
HV311_RS03615	COG0848	biopolymer transport protein
HV311_RS03635	COG0667	Aldo Keto reductase
HV311_RS03645	COG0840	transmembrane signaling receptor activity
HV311_RS03655	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
HV311_RS03660	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS03665	COG5557	Pfam Polysulphide reductase, NrfD
HV311_RS03670	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HV311_RS03675	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV311_RS03680	COG1773	rubredoxin
HV311_RS03690	COG0298	carbon dioxide binding
HV311_RS03695	COG0625	glutathione transferase activity
HV311_RS03700	COG0243	molybdopterin cofactor binding
HV311_RS03705	COG0754	glutathionylspermidine amidase activity
HV311_RS03725	COG1846	Transcriptional regulator
HV311_RS03840	COG0412	Dienelactone hydrolase
HV311_RS03855	COG1811	Na channel or pump
HV311_RS03860	COG1982	Orn Lys Arg decarboxylase major
HV311_RS03865	COG2211	Major facilitator Superfamily
HV311_RS03880	COG1194	a g-specific adenine glycosylase
HV311_RS03890	COG3171	Protein conserved in bacteria
HV311_RS03900	COG0252	asparaginase activity
HV311_RS03910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HV311_RS03915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HV311_RS03920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV311_RS03935	COG0762	integral membrane protein
HV311_RS03940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HV311_RS03945	COG2805	Type II/IV secretion system protein
HV311_RS03960	COG0189	ligase activity
HV311_RS03965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HV311_RS03970	COG2356	endonuclease I
HV311_RS03975	COG3091	SprT-like family
HV311_RS03980	COG2814	Major facilitator Superfamily
HV311_RS04000	COG1166	arginine decarboxylase activity
HV311_RS04015	COG0501	Belongs to the peptidase M48B family
HV311_RS04020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV311_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS04030	COG2213	PTS system mannitol-specific
HV311_RS04035	COG1063	alcohol dehydrogenase
HV311_RS04040	COG1494	fructose-1,6-bisphosphatase
HV311_RS04050	COG1072	(Pantothenic acid kinase))
HV311_RS04065	COG0191	fructose-bisphosphate aldolase activity
HV311_RS04070	COG0668	transmembrane transport
HV311_RS04080	COG1279	arginine transmembrane transporter activity
HV311_RS04085	COG2968	Membrane
HV311_RS04090	COG0583	DNA-binding transcription factor activity
HV311_RS04095	COG0427	acetyl-CoA hydrolase
HV311_RS04100	COG1024	Enoyl-CoA hydratase
HV311_RS04105	COG1703	isobutyryl-CoA mutase activity
HV311_RS04110	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV311_RS04110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV311_RS04125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HV311_RS04130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HV311_RS04150	COG0006	proline dipeptidase activity
HV311_RS04155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV311_RS04160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV311_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS04185	COG2723	6-phospho-beta-galactosidase activity
HV311_RS04190	COG1737	Transcriptional regulator
HV311_RS04200	COG1272	protein, Hemolysin III
HV311_RS04210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HV311_RS04235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HV311_RS04255	COG4942	peptidase
HV311_RS04270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV311_RS04275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV311_RS04280	COG0457	Tetratricopeptide repeat
HV311_RS04285	COG0438	transferase activity, transferring glycosyl groups
HV311_RS04290	COG1596	polysaccharide export
HV311_RS04295	COG1682	transport, permease protein
HV311_RS04300	COG1134	teichoic acid transport
HV311_RS04305	COG3524	carbohydrate:proton symporter activity
HV311_RS04310	COG4783	chaperone-mediated protein folding
HV311_RS04310	COG1560	Kdo2-lipid A biosynthetic process
HV311_RS04320	COG0457	Tetratricopeptide repeat
HV311_RS04325	COG1649	PFAM Uncharacterised BCR, COG1649
HV311_RS04325	COG0726	polysaccharide deacetylase
HV311_RS04330	COG1215	transferase activity, transferring glycosyl groups
HV311_RS04340	COG3592	Divergent 4Fe-4S mono-cluster
HV311_RS04345	COG2388	GCN5-related N-acetyl-transferase
HV311_RS04350	COG0583	DNA-binding transcription factor activity
HV311_RS04355	COG0666	response to abiotic stimulus
HV311_RS04365	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV311_RS04370	COG1304	FMN binding
HV311_RS04380	COG0549	Belongs to the carbamate kinase family
HV311_RS04385	COG0402	S-adenosylhomocysteine deaminase activity
HV311_RS04400	COG0814	amino acid
HV311_RS04415	COG0183	Belongs to the thiolase family
HV311_RS04425	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS04435	COG1794	racemase activity, acting on amino acids and derivatives
HV311_RS04440	COG0583	DNA-binding transcription factor activity
HV311_RS04450	COG1609	Transcriptional regulator
HV311_RS04470	COG0667	Aldo Keto reductase
HV311_RS04480	COG0861	Integral membrane protein TerC family
HV311_RS04510	COG2165	general secretion pathway protein
HV311_RS04515	COG4795	General secretion pathway protein
HV311_RS04525	COG4967	type IV pilus modification protein PilV
HV311_RS04530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HV311_RS04540	COG1074	ATP-dependent DNA helicase activity
HV311_RS04545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HV311_RS04550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HV311_RS04550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HV311_RS04555	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV311_RS04575	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HV311_RS04580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HV311_RS04585	COG2166	iron-sulfur cluster assembly
HV311_RS04590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HV311_RS04600	COG0583	DNA-binding transcription factor activity
HV311_RS04605	COG2363	Small membrane protein
HV311_RS04615	COG1349	DNA-binding transcription factor activity
HV311_RS04635	COG1129	ABC transporter
HV311_RS04640	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS04660	COG0235	Class ii aldolase
HV311_RS04665	COG1454	alcohol dehydrogenase
HV311_RS04675	COG1760	l-serine dehydratase
HV311_RS04680	COG0814	amino acid
HV311_RS04685	COG1611	Belongs to the LOG family
HV311_RS04700	COG3098	single-species biofilm formation
HV311_RS04705	COG0564	pseudouridine synthase activity
HV311_RS04710	COG0716	FMN binding
HV311_RS04715	COG2271	Major facilitator Superfamily
HV311_RS04720	COG4948	Mandelate Racemase Muconate Lactonizing
HV311_RS04725	COG4948	Mandelate Racemase Muconate Lactonizing
HV311_RS04730	COG1929	Belongs to the glycerate kinase type-1 family
HV311_RS04735	COG4999	Histidine kinase
HV311_RS04735	COG3850	Histidine kinase
HV311_RS04735	COG3437	response regulator, receiver
HV311_RS04735	COG2205	protein histidine kinase activity
HV311_RS04745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HV311_RS04750	COG3956	TIGRFAM MazG family protein
HV311_RS04800	COG3121	Chaperone
HV311_RS04820	COG0602	queuosine metabolic process
HV311_RS04825	COG1070	Carbohydrate kinase
HV311_RS04830	COG2223	nitrite transmembrane transporter activity
HV311_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS04840	COG0277	FAD linked oxidase domain protein
HV311_RS04845	COG0477	Major facilitator Superfamily
HV311_RS04850	COG2086	electron transfer activity
HV311_RS04855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HV311_RS04860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HV311_RS04865	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HV311_RS04870	COG0644	oxidoreductase
HV311_RS04875	COG0720	synthase
HV311_RS04895	COG1203	CRISPR-associated helicase, Cas3
HV311_RS04910	COG1857	crispr-associated protein
HV311_RS04925	COG1518	maintenance of DNA repeat elements
HV311_RS04930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV311_RS04935	COG2234	aminopeptidase activity
HV311_RS04990	COG4942	peptidase
HV311_RS04990	COG1388	LysM domain
HV311_RS05030	COG3188	usher protein
HV311_RS05060	COG2200	EAL domain
HV311_RS05065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV311_RS05070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV311_RS05075	COG1121	(ABC) transporter
HV311_RS05095	COG0309	Hydrogenase expression formation protein (HypE)
HV311_RS05100	COG0409	Hydrogenase expression formation protein
HV311_RS05105	COG0298	carbon dioxide binding
HV311_RS05110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HV311_RS05125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS05130	COG0651	ATP synthesis coupled electron transport
HV311_RS05135	COG0650	Formate hydrogenlyase subunit 4
HV311_RS05140	COG3261	NADH dehydrogenase
HV311_RS05140	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
HV311_RS05145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV311_RS05150	COG3260	NADH ubiquinone oxidoreductase 20
HV311_RS05160	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV311_RS05175	COG2723	6-phospho-beta-galactosidase activity
HV311_RS05180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS05180	COG1263	PTS System
HV311_RS05185	COG1609	Transcriptional regulator
HV311_RS05190	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS05195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
HV311_RS05215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV311_RS05215	COG0517	IMP dehydrogenase activity
HV311_RS05220	COG1349	DNA-binding transcription factor activity
HV311_RS05225	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS05240	COG3732	PTS system glucitol sorbitol-specific
HV311_RS05245	COG3730	PTS system glucitol sorbitol-specific
HV311_RS05250	COG2951	lytic endotransglycosylase activity
HV311_RS05255	COG1546	Belongs to the CinA family
HV311_RS05275	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HV311_RS05305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV311_RS05310	COG1238	metal cluster binding
HV311_RS05325	COG2814	Major facilitator Superfamily
HV311_RS05330	COG1566	PFAM secretion protein HlyD family protein
HV311_RS05335	COG1846	Transcriptional regulator
HV311_RS05345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV311_RS05350	COG2814	Major facilitator Superfamily
HV311_RS05360	COG4176	ABC-type proline glycine betaine transport system permease component
HV311_RS05375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HV311_RS05390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV311_RS05420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV311_RS05425	COG0640	Transcriptional regulator
HV311_RS05430	COG0401	homolog of Blt101
HV311_RS05435	COG1652	LysM domain
HV311_RS05440	COG1802	Transcriptional regulator
HV311_RS05445	COG1113	amino acid transport
HV311_RS05450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV311_RS05455	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS05460	COG0579	oxidoreductase
HV311_RS05510	COG3188	usher protein
HV311_RS05515	COG3121	Chaperone
HV311_RS05565	COG0438	transferase activity, transferring glycosyl groups
HV311_RS05570	COG0297	glycogen (starch) synthase activity
HV311_RS05570	COG0438	transferase activity, transferring glycosyl groups
HV311_RS05605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV311_RS05610	COG1757	Na H antiporter
HV311_RS05615	COG2169	Transcriptional regulator
HV311_RS05625	COG3829	transcription factor binding
HV311_RS05630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV311_RS05635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HV311_RS05640	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HV311_RS05645	COG2271	Major facilitator Superfamily
HV311_RS05650	COG2197	response regulator
HV311_RS05655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS05655	COG2198	Histidine kinase
HV311_RS05655	COG0784	Response regulator, receiver
HV311_RS05655	COG2205	protein histidine kinase activity
HV311_RS05675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV311_RS05680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS05685	COG3065	identical protein binding
HV311_RS05705	COG2200	EAL domain
HV311_RS05725	COG0582	viral genome integration into host DNA
HV311_RS05735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS05760	COG2867	negative regulation of translational initiation
HV311_RS05775	COG0497	DNA recombination
HV311_RS05790	COG4536	flavin adenine dinucleotide binding
HV311_RS05795	COG4137	Cytochrome C assembly protein
HV311_RS05800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HV311_RS05825	COG2885	chlorophyll binding
HV311_RS05830	COG2199	diguanylate cyclase activity
HV311_RS05845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV311_RS05850	COG1605	Chorismate mutase
HV311_RS05850	COG0287	Prephenate dehydrogenase
HV311_RS05855	COG1605	Chorismate mutase
HV311_RS05855	COG0077	Prephenate dehydratase
HV311_RS05865	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HV311_RS05870	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV311_RS05885	COG0542	response to heat
HV311_RS05910	COG0477	Major facilitator Superfamily
HV311_RS05915	COG5544	Lipoprotein
HV311_RS05920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV311_RS05930	COG3148	PFAM DTW domain containing protein
HV311_RS05935	COG3118	belongs to the thioredoxin family
HV311_RS05940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV311_RS05955	COG0513	Belongs to the DEAD box helicase family
HV311_RS05965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HV311_RS05975	COG1595	DNA-templated transcription, initiation
HV311_RS05985	COG3026	antisigma factor binding
HV311_RS05990	COG3086	response to oxidative stress
HV311_RS06000	COG0681	Belongs to the peptidase S26 family
HV311_RS06020	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HV311_RS06030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS06080	COG5532	Uncharacterized conserved protein (DUF2303)
HV311_RS06095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HV311_RS06120	COG4626	Terminase
HV311_RS06120	COG1802	Transcriptional regulator
HV311_RS06125	COG4725	Belongs to the MT-A70-like family
HV311_RS06130	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HV311_RS06140	COG1403	HNH endonuclease
HV311_RS06175	COG3179	chitinase
HV311_RS06205	COG0740	serine-type endopeptidase activity
HV311_RS06245	COG1196	nuclear chromosome segregation
HV311_RS06310	COG1737	Transcriptional regulator
HV311_RS06315	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HV311_RS06320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS06320	COG1263	PTS System
HV311_RS06325	COG0560	Phosphoserine phosphatase
HV311_RS06345	COG2205	protein histidine kinase activity
HV311_RS06350	COG3170	Tfp pilus assembly protein FimV
HV311_RS06355	COG2204	response regulator
HV311_RS06360	COG0347	Belongs to the P(II) protein family
HV311_RS06365	COG1017	nitric oxide dioxygenase activity
HV311_RS06365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV311_RS06375	COG1940	carbohydrate kinase activity
HV311_RS06380	COG0457	Tetratricopeptide repeat
HV311_RS06385	COG1879	ABC-type sugar transport system periplasmic component
HV311_RS06390	COG1129	ABC transporter
HV311_RS06395	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS06400	COG1063	alcohol dehydrogenase
HV311_RS06405	COG2017	converts alpha-aldose to the beta-anomer
HV311_RS06430	COG4638	Rieske (2fe-2S)
HV311_RS06435	COG0583	DNA-binding transcription factor activity
HV311_RS06440	COG3539	Fimbrial protein
HV311_RS06445	COG3188	usher protein
HV311_RS06460	COG2814	Major facilitator Superfamily
HV311_RS06465	COG3711	transcriptional antiterminator
HV311_RS06470	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV311_RS06470	COG0517	IMP dehydrogenase activity
HV311_RS06475	COG1069	ribulokinase activity
HV311_RS06485	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS06490	COG1129	ABC transporter
HV311_RS06500	COG3683	transport system, periplasmic component
HV311_RS06505	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
HV311_RS06530	COG0822	iron-sulfur transferase activity
HV311_RS06550	COG0633	Ferredoxin
HV311_RS06555	COG2975	iron-sulfur cluster assembly
HV311_RS06570	COG1737	Transcriptional regulator
HV311_RS06580	COG1263	PTS System
HV311_RS06580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS06580	COG2190	(PTS) system
HV311_RS06585	COG2897	thiosulfate sulfurtransferase activity
HV311_RS06590	COG2373	Large extracellular alpha-helical protein
HV311_RS06595	COG4953	penicillin-binding protein 1C
HV311_RS06625	COG2976	Protein conserved in bacteria
HV311_RS06650	COG1645	bacterial-type flagellum-dependent swarming motility
HV311_RS06660	COG0517	IMP dehydrogenase activity
HV311_RS06660	COG0516	GMP reductase activity
HV311_RS06695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HV311_RS06705	COG2723	6-phospho-beta-galactosidase activity
HV311_RS06715	COG2233	PERMEase
HV311_RS06725	COG1393	Belongs to the ArsC family
HV311_RS06730	COG4783	chaperone-mediated protein folding
HV311_RS06735	COG0628	permease
HV311_RS06740	COG3366	ferrous iron transmembrane transporter activity
HV311_RS06745	COG0700	Nucleoside recognition
HV311_RS06750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV311_RS06755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HV311_RS06760	COG2716	regulation of RNA biosynthetic process
HV311_RS06770	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HV311_RS06780	COG2321	neutral zinc metallopeptidase
HV311_RS06790	COG0400	carboxylic ester hydrolase activity
HV311_RS06805	COG1393	Belongs to the ArsC family
HV311_RS06815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV311_RS06820	COG3850	Histidine kinase
HV311_RS06825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS06825	COG0493	'glutamate synthase
HV311_RS06835	COG5342	invasion associated locus B
HV311_RS06840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV311_RS06870	COG4766	ethanolamine catabolic process
HV311_RS06875	COG4812	Cobalamin adenosyltransferase
HV311_RS06935	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HV311_RS06940	COG2207	Transcriptional regulator
HV311_RS06950	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV311_RS06970	COG2837	iron assimilation
HV311_RS06975	COG0165	Argininosuccinate lyase
HV311_RS06980	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV311_RS06985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV311_RS06990	COG2186	Transcriptional regulator
HV311_RS07000	COG4150	thiosulfate binding
HV311_RS07005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HV311_RS07010	COG4208	sulfate ABC transporter
HV311_RS07015	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HV311_RS07080	COG3530	Putative quorum-sensing-regulated virulence factor
HV311_RS07085	COG0385	Bile acid
HV311_RS07090	COG0583	DNA-binding transcription factor activity
HV311_RS07120	COG3415	Transposase
HV311_RS07125	COG3415	Transposase
HV311_RS07140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV311_RS07155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV311_RS07160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV311_RS07165	COG1263	PTS System
HV311_RS07165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS07175	COG0667	Aldo Keto reductase
HV311_RS07180	COG3961	Belongs to the TPP enzyme family
HV311_RS07195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS07200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS07205	COG0006	proline dipeptidase activity
HV311_RS07210	COG1363	Peptidase, m42
HV311_RS07225	COG2207	Transcriptional regulator
HV311_RS07230	COG3279	Response regulator of the LytR AlgR family
HV311_RS07235	COG3275	phosphorelay sensor kinase activity
HV311_RS07240	COG0436	Aminotransferase
HV311_RS07255	COG1560	Kdo2-lipid A biosynthetic process
HV311_RS07285	COG3122	Protein conserved in bacteria
HV311_RS07290	COG0840	transmembrane signaling receptor activity
HV311_RS07315	COG2116	formate transmembrane transporter activity
HV311_RS07325	COG2067	long-chain fatty acid transport protein
HV311_RS07330	COG3691	Protein conserved in bacteria
HV311_RS07345	COG2062	phosphohistidine phosphatase, SixA
HV311_RS07370	COG0730	response to heat
HV311_RS07375	COG3101	peptidyl-lysine hydroxylation
HV311_RS07390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV311_RS07430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HV311_RS07440	COG0586	Pfam SNARE associated Golgi protein
HV311_RS07450	COG0285	dihydrofolate synthase activity
HV311_RS07455	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
HV311_RS07460	COG1286	toxin biosynthetic process
HV311_RS07465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HV311_RS07470	COG0163	prenyltransferase activity
HV311_RS07500	COG4598	ABC transporter
HV311_RS07505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV311_RS07510	COG1090	epimerase
HV311_RS07515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HV311_RS07520	COG0625	glutathione transferase activity
HV311_RS07525	COG0625	glutathione transferase activity
HV311_RS07530	COG0622	Phosphoesterase
HV311_RS07540	COG1288	antiporter activity
HV311_RS07565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV311_RS07570	COG0490	domain, Protein
HV311_RS07570	COG0471	metal ion transport
HV311_RS07580	COG0436	Aminotransferase
HV311_RS07590	COG0583	DNA-binding transcription factor activity
HV311_RS07610	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
HV311_RS07635	COG0839	Belongs to the complex I subunit 6 family
HV311_RS07645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HV311_RS07650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV311_RS07660	COG0784	Response regulator, receiver
HV311_RS07660	COG0835	chemotaxis
HV311_RS07670	COG2153	protein acetylation
HV311_RS07675	COG4575	ribosome binding
HV311_RS07680	COG1169	isochorismate synthase
HV311_RS07765	COG1414	Transcriptional regulator
HV311_RS07775	COG2271	Major facilitator Superfamily
HV311_RS07795	COG0247	lactate metabolic process
HV311_RS07805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HV311_RS07810	COG2271	Major facilitator Superfamily
HV311_RS07815	COG0584	glycerophosphoryl diester phosphodiesterase
HV311_RS07820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV311_RS07845	COG0183	Belongs to the thiolase family
HV311_RS07850	COG2031	fatty acid transporter
HV311_RS07855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV311_RS07860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV311_RS07865	COG2204	response regulator
HV311_RS07870	COG3852	Histidine kinase
HV311_RS07885	COG2198	Histidine kinase
HV311_RS07885	COG0642	Histidine kinase
HV311_RS07895	COG1477	protein flavinylation
HV311_RS07900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HV311_RS07900	COG2169	Transcriptional regulator
HV311_RS07905	COG3145	DNA-N1-methyladenine dioxygenase activity
HV311_RS07910	COG4615	Cyclic peptide transporter
HV311_RS07915	COG2239	Acts as a magnesium transporter
HV311_RS07920	COG0659	secondary active sulfate transmembrane transporter activity
HV311_RS07935	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS07935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HV311_RS07940	COG3062	negative regulation of establishment of protein localization
HV311_RS07950	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS07955	COG0348	domain, Protein
HV311_RS07960	COG3043	anaerobic respiration
HV311_RS07965	COG3005	denitrification pathway
HV311_RS07970	COG4133	protoheme IX ABC transporter activity
HV311_RS07980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV311_RS07985	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HV311_RS07995	COG1138	Cytochrome C-type biogenesis protein
HV311_RS08000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV311_RS08005	COG4235	cytochrome complex assembly
HV311_RS08005	COG3088	subunit of a heme lyase
HV311_RS08010	COG2197	response regulator
HV311_RS08020	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS08060	COG1061	Type III restriction enzyme res subunit
HV311_RS08065	COG1187	pseudouridine synthase activity
HV311_RS08070	COG2814	Major facilitator Superfamily
HV311_RS08080	COG4172	Belongs to the ABC transporter superfamily
HV311_RS08085	COG4239	(ABC) transporter, permease
HV311_RS08090	COG4174	ABC transporter (Permease)
HV311_RS08095	COG4166	transmembrane transport
HV311_RS08100	COG2200	EAL domain
HV311_RS08105	COG0791	NLP P60 protein
HV311_RS08110	COG0671	phosphoesterase, PA-phosphatase related
HV311_RS08115	COG0523	cobalamin synthesis protein
HV311_RS08120	COG0246	Mannitol dehydrogenase
HV311_RS08125	COG1312	Catalyzes the dehydration of D-mannonate
HV311_RS08130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV311_RS08135	COG3005	denitrification pathway
HV311_RS08145	COG3381	protein complex oligomerization
HV311_RS08170	COG1105	Belongs to the carbohydrate kinase PfkB family
HV311_RS08175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS08175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS08175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HV311_RS08180	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV311_RS08190	COG0583	DNA-binding transcription factor activity
HV311_RS08195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS08200	COG2313	pseudouridylate synthase activity
HV311_RS08205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV311_RS08210	COG1522	sequence-specific DNA binding
HV311_RS08210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS08220	COG2855	membrane
HV311_RS08225	COG0583	DNA-binding transcription factor activity
HV311_RS08230	COG0833	amino acid
HV311_RS08255	COG2311	Membrane
HV311_RS08270	COG1129	ABC transporter
HV311_RS08285	COG0493	'glutamate synthase
HV311_RS08295	COG2949	membrane
HV311_RS08305	COG1346	cytolysis
HV311_RS08320	COG2271	Major facilitator Superfamily
HV311_RS08335	COG0625	glutathione transferase activity
HV311_RS08340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV311_RS08345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV311_RS08360	COG0586	Pfam SNARE associated Golgi protein
HV311_RS08370	COG1686	Belongs to the peptidase S11 family
HV311_RS08375	COG0277	FAD linked oxidase domain protein
HV311_RS08380	COG1472	Belongs to the glycosyl hydrolase 3 family
HV311_RS08385	COG1732	Glycine betaine
HV311_RS08390	COG1174	glycine betaine transport
HV311_RS08395	COG1125	glycine betaine transport
HV311_RS08400	COG1174	glycine betaine transport
HV311_RS08410	COG0789	Transcriptional regulator
HV311_RS08415	COG3275	phosphorelay sensor kinase activity
HV311_RS08425	COG4807	Protein conserved in bacteria
HV311_RS08430	COG4808	Protein conserved in bacteria
HV311_RS08455	COG3121	Chaperone
HV311_RS08460	COG3188	usher protein
HV311_RS08470	COG5455	response to cobalt ion
HV311_RS08480	COG0351	phosphomethylpyrimidine kinase
HV311_RS08485	COG2188	Transcriptional regulator
HV311_RS08490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS08495	COG1397	ADP-ribosylglycohydrolase
HV311_RS08500	COG2211	Major facilitator Superfamily
HV311_RS08505	COG1830	Aldolase
HV311_RS08515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS08520	COG4160	amino acid transport
HV311_RS08525	COG4215	(ABC) transporter
HV311_RS08530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS08535	COG1126	abc transporter atp-binding protein
HV311_RS08550	COG3023	N-Acetylmuramoyl-L-alanine amidase
HV311_RS08555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV311_RS08560	COG0702	epimerase
HV311_RS08565	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
HV311_RS08570	COG0028	Belongs to the TPP enzyme family
HV311_RS08580	COG4529	Protein conserved in bacteria
HV311_RS08585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV311_RS08595	COG2431	L-lysine efflux transmembrane transporter activity
HV311_RS08605	COG3593	DNA synthesis involved in DNA repair
HV311_RS08610	COG2990	Protein conserved in bacteria
HV311_RS08615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS08625	COG1278	Cold shock
HV311_RS08635	COG0542	response to heat
HV311_RS08640	COG0826	peptidase U32
HV311_RS08650	COG0745	RESPONSE REGULATOR receiver
HV311_RS08655	COG2205	protein histidine kinase activity
HV311_RS08700	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HV311_RS08705	COG5002	protein histidine kinase activity
HV311_RS08705	COG5001	Diguanylate cyclase
HV311_RS08705	COG3447	MASE1 domain protein
HV311_RS08720	COG2982	Protein involved in outer membrane biogenesis
HV311_RS08725	COG1253	flavin adenine dinucleotide binding
HV311_RS08745	COG0463	Glycosyl transferase, family 2
HV311_RS08750	COG1045	serine acetyltransferase
HV311_RS08755	COG0438	transferase activity, transferring glycosyl groups
HV311_RS08765	COG1216	Glycosyl transferase, family 2
HV311_RS08770	COG0110	maltose O-acetyltransferase activity
HV311_RS08775	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HV311_RS08780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV311_RS08785	COG1051	belongs to the nudix hydrolase family
HV311_RS08790	COG0297	glycogen (starch) synthase activity
HV311_RS08795	COG0662	Cupin 2, conserved barrel domain protein
HV311_RS08795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HV311_RS08800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HV311_RS08805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HV311_RS08810	COG2244	polysaccharide biosynthetic process
HV311_RS08815	COG2327	Polysaccharide pyruvyl transferase
HV311_RS08845	COG1091	dTDP-4-dehydrorhamnose reductase activity
HV311_RS08870	COG1216	Glycosyl transferase, family 2
HV311_RS08870	COG0438	transferase activity, transferring glycosyl groups
HV311_RS08940	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HV311_RS08970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HV311_RS08975	COG0583	DNA-binding transcription factor activity
HV311_RS08985	COG0531	amino acid
HV311_RS08990	COG2925	Exonuclease
HV311_RS09020	COG1289	transmembrane transporter activity
HV311_RS09055	COG4656	Part of a membrane complex involved in electron transport
HV311_RS09065	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS09075	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HV311_RS09245	COG1376	ErfK ybiS ycfS ynhG family protein
HV311_RS09255	COG1178	ABC-type Fe3 transport system permease component
HV311_RS09260	COG1840	ABC-type Fe3 transport system, periplasmic component
HV311_RS09270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HV311_RS09330	COG4227	nucleotidyltransferase activity
HV311_RS09360	COG3504	Conjugal transfer protein
HV311_RS09365	COG3736	Type IV secretory pathway, component VirB8
HV311_RS09390	COG3451	type IV secretory pathway VirB4
HV311_RS09410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV311_RS09425	COG2207	Transcriptional regulator
HV311_RS09440	COG1566	PFAM secretion protein HlyD family protein
HV311_RS09445	COG4977	sequence-specific DNA binding
HV311_RS09455	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS09510	COG1609	Transcriptional regulator
HV311_RS09520	COG2223	nitrite transmembrane transporter activity
HV311_RS09550	COG1737	Transcriptional regulator
HV311_RS09565	COG0582	viral genome integration into host DNA
HV311_RS09600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV311_RS09605	COG1418	mRNA catabolic process
HV311_RS09610	COG0270	DNA (cytosine-5-)-methyltransferase activity
HV311_RS09615	COG3727	T/G mismatch-specific endonuclease activity
HV311_RS09620	COG0697	spore germination
HV311_RS09625	COG2354	Protein conserved in bacteria
HV311_RS09630	COG5475	Uncharacterized small protein (DUF2158)
HV311_RS09690	COG2882	bacterial-type flagellum organization
HV311_RS09720	COG0425	Belongs to the sulfur carrier protein TusA family
HV311_RS09735	COG0366	Alpha amylase catalytic
HV311_RS09775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS09785	COG0765	amino acid transport
HV311_RS09790	COG1126	abc transporter atp-binding protein
HV311_RS09795	COG2197	response regulator
HV311_RS09805	COG2197	response regulator
HV311_RS09840	COG1278	Cold shock
HV311_RS09850	COG0431	NADPH-dependent FMN reductase
HV311_RS09855	COG0640	Transcriptional regulator
HV311_RS09885	COG1305	Transglutaminase-like
HV311_RS09895	COG2608	mercury ion transmembrane transporter activity
HV311_RS09900	COG3012	SEC-C Motif Domain Protein
HV311_RS09900	COG3318	Belongs to the UPF0149 family
HV311_RS09905	COG0814	amino acid
HV311_RS09915	COG1528	Iron-storage protein
HV311_RS09930	COG0477	Major facilitator Superfamily
HV311_RS09940	COG1528	Iron-storage protein
HV311_RS09950	COG1879	ABC-type sugar transport system periplasmic component
HV311_RS09955	COG1129	ABC transporter
HV311_RS09960	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS10005	COG0835	chemotaxis
HV311_RS10010	COG1301	dicarboxylic acid transport
HV311_RS10020	COG0840	transmembrane signaling receptor activity
HV311_RS10035	COG0745	RESPONSE REGULATOR receiver
HV311_RS10050	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HV311_RS10075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HV311_RS10090	COG3102	Protein conserved in bacteria
HV311_RS10110	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HV311_RS10115	COG1801	Protein of unknown function DUF72
HV311_RS10120	COG1335	isochorismatase
HV311_RS10130	COG0494	nUDIX hydrolase
HV311_RS10150	COG2255	four-way junction helicase activity
HV311_RS10155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HV311_RS10175	COG1187	pseudouridine synthase activity
HV311_RS10180	COG0538	isocitrate dehydrogenase activity
HV311_RS10185	COG2814	Major facilitator Superfamily
HV311_RS10190	COG1414	Transcriptional regulator
HV311_RS10220	COG0768	penicillin binding
HV311_RS10225	COG2226	methyltransferase
HV311_RS10240	COG3716	PTS system mannose fructose sorbose family IID component
HV311_RS10245	COG3715	PTS system
HV311_RS10250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS10250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS10255	COG1253	flavin adenine dinucleotide binding
HV311_RS10260	COG2200	EAL domain
HV311_RS10265	COG1760	l-serine dehydratase
HV311_RS10285	COG0251	oxidation-reduction process
HV311_RS10290	COG1199	ATP-dependent helicase activity
HV311_RS10295	COG1214	PFAM Peptidase M22, glycoprotease
HV311_RS10300	COG3065	identical protein binding
HV311_RS10305	COG0318	PFAM AMP-dependent synthetase and ligase
HV311_RS10310	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HV311_RS10315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HV311_RS10320	COG4638	Rieske (2fe-2S)
HV311_RS10325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV311_RS10330	COG0473	3-isopropylmalate dehydrogenase activity
HV311_RS10335	COG0583	DNA-binding transcription factor activity
HV311_RS10345	COG2894	cell division
HV311_RS10360	COG0179	Fumarylacetoacetate (FAA) hydrolase
HV311_RS10385	COG0629	single-stranded DNA binding
HV311_RS10455	COG2719	SpoVR family
HV311_RS10465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HV311_RS10475	COG1619	proteins homologs of microcin C7 resistance protein MccF
HV311_RS10500	COG0157	Belongs to the NadC ModD family
HV311_RS10505	COG0500	methyltransferase
HV311_RS10510	COG1120	ATPase activity
HV311_RS10515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS10520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV311_RS10535	COG1461	Dihydroxyacetone kinase
HV311_RS10540	COG2376	Dihydroxyacetone kinase
HV311_RS10545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HV311_RS10570	COG0789	Transcriptional regulator
HV311_RS10575	COG2200	EAL domain
HV311_RS10605	COG0702	epimerase
HV311_RS10615	COG0667	Aldo Keto reductase
HV311_RS10620	COG0656	L-ascorbic acid biosynthetic process
HV311_RS10630	COG3039	Transposase
HV311_RS10665	COG5002	protein histidine kinase activity
HV311_RS10690	COG0583	DNA-binding transcription factor activity
HV311_RS10695	COG2954	triphosphatase activity
HV311_RS10705	COG0471	metal ion transport
HV311_RS10720	COG0582	viral genome integration into host DNA
HV311_RS10725	COG1414	Transcriptional regulator
HV311_RS10745	COG0800	Aldolase
HV311_RS10750	COG3734	2-keto-3-deoxy-galactonokinase
HV311_RS10755	COG1414	Transcriptional regulator
HV311_RS10760	COG1454	alcohol dehydrogenase
HV311_RS10775	COG0012	GTP binding
HV311_RS10790	COG0527	aspartate kinase activity
HV311_RS10795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV311_RS10800	COG0076	glutamate decarboxylase activity
HV311_RS10805	COG0659	secondary active sulfate transmembrane transporter activity
HV311_RS10835	COG2890	protein-(glutamine-N5) methyltransferase activity
HV311_RS10840	COG3094	Invasion gene expression up-regulator, SirB
HV311_RS10855	COG0387	Pfam Sodium calcium exchanger
HV311_RS10860	COG4572	Cation transport regulator
HV311_RS10865	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HV311_RS10875	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HV311_RS10880	COG4932	domain protein
HV311_RS10885	COG2197	response regulator
HV311_RS10890	COG3850	Histidine kinase
HV311_RS10895	COG2223	nitrite transmembrane transporter activity
HV311_RS10900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV311_RS10905	COG1140	nitrate reductase beta subunit
HV311_RS10910	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV311_RS10915	COG2181	nitrate reductase activity
HV311_RS10940	COG0788	formyltetrahydrofolate deformylase activity
HV311_RS10950	COG1752	Esterase of the alpha-beta hydrolase superfamily
HV311_RS10955	COG0745	RESPONSE REGULATOR receiver
HV311_RS10960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HV311_RS10975	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS10975	COG1454	alcohol dehydrogenase
HV311_RS10980	COG2095	MarC family integral membrane protein
HV311_RS11000	COG0444	Belongs to the ABC transporter superfamily
HV311_RS11010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV311_RS11030	COG2350	Protein conserved in bacteria
HV311_RS11055	COG3047	cAMP biosynthetic process
HV311_RS11065	COG3706	GGDEF domain
HV311_RS11105	COG0009	L-threonylcarbamoyladenylate synthase
HV311_RS11110	COG1187	pseudouridine synthase activity
HV311_RS11120	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS11125	COG0616	signal peptide processing
HV311_RS11140	COG0583	DNA-binding transcription factor activity
HV311_RS11155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HV311_RS11165	COG0671	phosphoesterase, PA-phosphatase related
HV311_RS11170	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
HV311_RS11175	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HV311_RS11185	COG0023	Translation Initiation Factor
HV311_RS11195	COG1349	DNA-binding transcription factor activity
HV311_RS11205	COG5001	Diguanylate cyclase
HV311_RS11215	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV311_RS11215	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV311_RS11220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HV311_RS11235	COG4172	Belongs to the ABC transporter superfamily
HV311_RS11240	COG4171	peptide transport system, permease
HV311_RS11265	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HV311_RS11270	COG1842	Phage shock protein A
HV311_RS11280	COG1983	PspC domain protein
HV311_RS11290	COG0366	Alpha amylase catalytic
HV311_RS11295	COG1653	transport
HV311_RS11300	COG1175	transmembrane transport
HV311_RS11305	COG0395	ABC-type sugar transport system, permease component
HV311_RS11310	COG1063	alcohol dehydrogenase
HV311_RS11315	COG1082	Xylose isomerase domain protein TIM barrel
HV311_RS11320	COG0673	inositol 2-dehydrogenase activity
HV311_RS11325	COG1554	hydrolase, family 65, central catalytic
HV311_RS11330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV311_RS11345	COG1609	Transcriptional regulator
HV311_RS11350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HV311_RS11355	COG3106	COG3106 Predicted ATPase
HV311_RS11370	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HV311_RS11375	COG4948	Mandelate Racemase Muconate Lactonizing
HV311_RS11380	COG2866	Carboxypeptidase
HV311_RS11385	COG4166	transmembrane transport
HV311_RS11390	COG1349	DNA-binding transcription factor activity
HV311_RS11395	COG0346	lactoylglutathione lyase activity
HV311_RS11410	COG0668	transmembrane transport
HV311_RS11415	COG3182	Iron-regulated membrane protein
HV311_RS11435	COG2840	Smr protein MutS2
HV311_RS11440	COG3706	GGDEF domain
HV311_RS11450	COG0840	transmembrane signaling receptor activity
HV311_RS11465	COG0513	Belongs to the DEAD box helicase family
HV311_RS11500	COG0589	response to stress
HV311_RS11515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV311_RS11520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HV311_RS11520	COG0674	pyruvate-flavodoxin oxidoreductase activity
HV311_RS11520	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HV311_RS11520	COG1013	pyruvate-flavodoxin oxidoreductase activity
HV311_RS11525	COG3042	response to heat
HV311_RS11530	COG3187	Heat shock protein
HV311_RS11535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HV311_RS11540	COG2911	Protein conserved in bacteria
HV311_RS11550	COG3784	Protein of unknown function (DUF1318)
HV311_RS11565	COG1643	Atp-dependent helicase
HV311_RS11570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV311_RS11575	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS11580	COG3038	cytochrome b561
HV311_RS11585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV311_RS11590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV311_RS11675	COG0840	transmembrane signaling receptor activity
HV311_RS11680	COG0583	DNA-binding transcription factor activity
HV311_RS11685	COG1227	inorganic diphosphatase activity
HV311_RS11690	COG5383	Protein conserved in bacteria
HV311_RS11700	COG2841	Protein conserved in bacteria
HV311_RS11705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV311_RS11710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HV311_RS11715	COG1275	C4-dicarboxylate transporter malic acid transport protein
HV311_RS11720	COG0500	methyltransferase
HV311_RS11740	COG3135	benzoate transporter
HV311_RS11745	COG1396	sequence-specific DNA binding
HV311_RS11750	COG0826	peptidase U32
HV311_RS11765	COG1294	oxidase, subunit
HV311_RS11770	COG1271	oxidase subunit
HV311_RS11775	COG1724	mRNA binding
HV311_RS11780	COG1598	PFAM Uncharacterised protein family UPF0150
HV311_RS11785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV311_RS11790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV311_RS11795	COG3842	ATPase activity
HV311_RS11800	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV311_RS11805	COG1177	transmembrane transport
HV311_RS11815	COG2814	Major facilitator Superfamily
HV311_RS11850	COG0747	negative chemotaxis
HV311_RS11860	COG3238	Protein conserved in bacteria
HV311_RS11865	COG1247	-acetyltransferase
HV311_RS11875	COG2130	NADP-dependent
HV311_RS11880	COG4772	TonB-dependent receptor
HV311_RS11900	COG0840	transmembrane signaling receptor activity
HV311_RS11905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV311_RS11910	COG1473	amidohydrolase
HV311_RS11915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HV311_RS11920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
HV311_RS11935	COG1126	abc transporter atp-binding protein
HV311_RS11940	COG0625	glutathione transferase activity
HV311_RS11945	COG2271	Major facilitator Superfamily
HV311_RS11955	COG1609	Transcriptional regulator
HV311_RS11965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HV311_RS11970	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HV311_RS11975	COG0384	phenazine biosynthesis protein PhzF
HV311_RS11980	COG2181	nitrate reductase activity
HV311_RS11985	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HV311_RS11990	COG1140	nitrate reductase beta subunit
HV311_RS11995	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HV311_RS12000	COG2223	nitrite transmembrane transporter activity
HV311_RS12040	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS12045	COG2864	formate dehydrogenase
HV311_RS12050	COG0488	(ABC) transporter
HV311_RS12065	COG1764	response to oxidative stress
HV311_RS12070	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS12075	COG2610	gluconate transmembrane transporter activity
HV311_RS12080	COG1250	3-hydroxyacyl-CoA dehydrogenase
HV311_RS12090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HV311_RS12095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HV311_RS12105	COG4608	Belongs to the ABC transporter superfamily
HV311_RS12110	COG0444	Belongs to the ABC transporter superfamily
HV311_RS12115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV311_RS12120	COG0601	transmembrane transport
HV311_RS12125	COG0747	negative chemotaxis
HV311_RS12130	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HV311_RS12145	COG0840	transmembrane signaling receptor activity
HV311_RS12150	COG1649	PFAM Uncharacterised BCR, COG1649
HV311_RS12155	COG4628	conserved protein (DUF2132)
HV311_RS12295	COG1783	phage Terminase large subunit
HV311_RS12390	COG3772	lysozyme
HV311_RS12400	COG2801	Transposase and inactivated derivatives
HV311_RS12420	COG3781	membrane
HV311_RS12445	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS12450	COG0583	DNA-binding transcription factor activity
HV311_RS12465	COG1846	Transcriptional regulator
HV311_RS12480	COG0697	spore germination
HV311_RS12485	COG2814	Major facilitator Superfamily
HV311_RS12490	COG0410	ABC transporter
HV311_RS12495	COG1129	ABC transporter
HV311_RS12520	COG0339	signal peptide processing
HV311_RS12525	COG4221	oxidoreductase activity
HV311_RS12530	COG1802	Transcriptional regulator
HV311_RS12540	COG0246	Mannitol dehydrogenase
HV311_RS12545	COG0477	Major facilitator Superfamily
HV311_RS12550	COG1063	alcohol dehydrogenase
HV311_RS12555	COG4948	Mandelate Racemase Muconate Lactonizing
HV311_RS12570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV311_RS12585	COG0243	molybdopterin cofactor binding
HV311_RS12590	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS12595	COG3302	dmso reductase anchor subunit
HV311_RS12600	COG3381	protein complex oligomerization
HV311_RS12610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV311_RS12615	COG1940	carbohydrate kinase activity
HV311_RS12620	COG0583	DNA-binding transcription factor activity
HV311_RS12625	COG2814	Major facilitator Superfamily
HV311_RS12635	COG5002	protein histidine kinase activity
HV311_RS12640	COG0745	RESPONSE REGULATOR receiver
HV311_RS12655	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HV311_RS12665	COG3591	Belongs to the peptidase S1B family
HV311_RS12680	COG0628	permease
HV311_RS12685	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HV311_RS12690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HV311_RS12700	COG0531	amino acid
HV311_RS12710	COG3136	membrane protein required for alginate biosynthesis
HV311_RS12715	COG0745	RESPONSE REGULATOR receiver
HV311_RS12720	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HV311_RS12730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV311_RS12740	COG2205	protein histidine kinase activity
HV311_RS12755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS12755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS12760	COG1482	cell wall glycoprotein biosynthetic process
HV311_RS12765	COG5339	Protein conserved in bacteria
HV311_RS12770	COG1609	Transcriptional regulator
HV311_RS12775	COG1263	PTS System
HV311_RS12775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS12780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HV311_RS12790	COG0673	inositol 2-dehydrogenase activity
HV311_RS12840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HV311_RS12850	COG0625	glutathione transferase activity
HV311_RS12855	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
HV311_RS12870	COG3895	Periplasmic Protein
HV311_RS12895	COG1566	PFAM secretion protein HlyD family protein
HV311_RS12910	COG4989	oxidoreductase activity
HV311_RS12915	COG3313	Fe-S protein
HV311_RS12920	COG1309	transcriptional regulator
HV311_RS12925	COG1902	pentaerythritol trinitrate reductase activity
HV311_RS12930	COG0346	lactoylglutathione lyase activity
HV311_RS12940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV311_RS12945	COG0791	NLP P60 protein
HV311_RS12950	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HV311_RS12955	COG2814	Major facilitator Superfamily
HV311_RS12970	COG0583	DNA-binding transcription factor activity
HV311_RS12975	COG2814	Major facilitator Superfamily
HV311_RS12980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HV311_RS12985	COG0307	riboflavin synthase, alpha
HV311_RS12995	COG0564	pseudouridine synthase activity
HV311_RS13010	COG0251	oxidation-reduction process
HV311_RS13035	COG5001	Diguanylate cyclase
HV311_RS13035	COG3300	MHYT domain
HV311_RS13040	COG3272	Protein of unknown function (DUF1722)
HV311_RS13045	COG0628	permease
HV311_RS13080	COG0582	viral genome integration into host DNA
HV311_RS13085	COG0583	DNA-binding transcription factor activity
HV311_RS13090	COG0477	Major facilitator Superfamily
HV311_RS13105	COG1942	4-Oxalocrotonate Tautomerase
HV311_RS13115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HV311_RS13125	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS13140	COG1074	ATP-dependent DNA helicase activity
HV311_RS13145	COG1196	nuclear chromosome segregation
HV311_RS13150	COG3039	Transposase
HV311_RS13160	COG0456	acetyltransferase
HV311_RS13165	COG0251	oxidation-reduction process
HV311_RS13180	COG1114	Component of the transport system for branched-chain amino acids
HV311_RS13210	COG4977	sequence-specific DNA binding
HV311_RS13220	COG0386	Belongs to the glutathione peroxidase family
HV311_RS13240	COG1120	ATPase activity
HV311_RS13245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS13250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV311_RS13255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HV311_RS13270	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HV311_RS13280	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS13295	COG1113	amino acid transport
HV311_RS13305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS13315	COG0765	amino acid transport
HV311_RS13320	COG0765	amino acid transport
HV311_RS13330	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HV311_RS13335	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS13345	COG2414	aldehyde ferredoxin oxidoreductase
HV311_RS13350	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS13385	COG1464	Belongs to the NlpA lipoprotein family
HV311_RS13390	COG2011	ABC-type metal ion transport system permease component
HV311_RS13410	COG1376	ErfK ybiS ycfS ynhG family protein
HV311_RS13425	COG0719	Fe-S assembly protein
HV311_RS13430	COG0396	ATPase activity
HV311_RS13435	COG0719	Fe-S assembly protein
HV311_RS13440	COG0316	Belongs to the HesB IscA family
HV311_RS13460	COG2050	protein possibly involved in aromatic compounds catabolism
HV311_RS13465	COG0277	FAD linked oxidase domain protein
HV311_RS13465	COG0247	lactate metabolic process
HV311_RS13470	COG0628	permease
HV311_RS13485	COG0738	Major facilitator superfamily
HV311_RS13490	COG2271	Major facilitator Superfamily
HV311_RS13505	COG4670	ketone body catabolic process
HV311_RS13510	COG1960	acyl-CoA dehydrogenase activity
HV311_RS13515	COG1917	Cupin 2, conserved barrel domain protein
HV311_RS13515	COG2207	Transcriptional regulator
HV311_RS13520	COG2086	electron transfer activity
HV311_RS13525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HV311_RS13530	COG0644	oxidoreductase
HV311_RS13535	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HV311_RS13540	COG0318	PFAM AMP-dependent synthetase and ligase
HV311_RS13545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV311_RS13545	COG0574	Belongs to the PEP-utilizing enzyme family
HV311_RS13555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV311_RS13560	COG4256	Hemin uptake protein
HV311_RS13565	COG4771	TonB-dependent receptor
HV311_RS13570	COG3720	iron ion transport
HV311_RS13575	COG4558	Periplasmic binding protein
HV311_RS13580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS13600	COG0791	NLP P60 protein
HV311_RS13610	COG0386	Belongs to the glutathione peroxidase family
HV311_RS13625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS13640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HV311_RS13670	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HV311_RS13690	COG3137	Salt-induced outer membrane protein
HV311_RS13695	COG1105	Belongs to the carbohydrate kinase PfkB family
HV311_RS13700	COG3001	Fructosamine kinase
HV311_RS13710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV311_RS13720	COG1988	membrane-bound metal-dependent
HV311_RS13725	COG1823	symporter activity
HV311_RS13735	COG0753	catalase activity
HV311_RS13745	COG1486	melibiose metabolic process
HV311_RS13750	COG2169	Transcriptional regulator
HV311_RS13750	COG1917	Cupin 2, conserved barrel domain protein
HV311_RS13755	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV311_RS13760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV311_RS13765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV311_RS13770	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV311_RS13780	COG0322	excinuclease ABC activity
HV311_RS13790	COG3678	ATP-independent chaperone mediated protein folding
HV311_RS13820	COG0708	Exodeoxyribonuclease III
HV311_RS13825	COG0398	Pfam SNARE associated Golgi protein
HV311_RS13830	COG0398	Pfam SNARE associated Golgi protein
HV311_RS13835	COG4134	Bacterial extracellular solute-binding protein
HV311_RS13840	COG4135	transport system, permease component
HV311_RS13845	COG4136	ATPase activity
HV311_RS13850	COG2897	thiosulfate sulfurtransferase activity
HV311_RS13855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HV311_RS13860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HV311_RS13865	COG0494	nUDIX hydrolase
HV311_RS13880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV311_RS13890	COG0778	Nitroreductase
HV311_RS13895	COG0616	signal peptide processing
HV311_RS13900	COG0252	asparaginase activity
HV311_RS13905	COG1335	isochorismatase
HV311_RS13920	COG3139	Protein of unknown function (DUF1315)
HV311_RS13940	COG0656	L-ascorbic acid biosynthetic process
HV311_RS13955	COG3713	MltA-interacting MipA family protein
HV311_RS13960	COG2766	serine protein kinase
HV311_RS13970	COG0110	maltose O-acetyltransferase activity
HV311_RS13980	COG2226	methyltransferase
HV311_RS13985	COG2199	diguanylate cyclase activity
HV311_RS13990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV311_RS14000	COG2207	Transcriptional regulator
HV311_RS14005	COG2807	transmembrane transport
HV311_RS14010	COG0504	CTP synthase activity
HV311_RS14015	COG3189	MarR family transcriptional regulator
HV311_RS14020	COG3042	response to heat
HV311_RS14025	COG2203	Gaf domain
HV311_RS14025	COG2199	diguanylate cyclase activity
HV311_RS14040	COG2261	transglycosylase associated protein
HV311_RS14045	COG3383	formate dehydrogenase (NAD+) activity
HV311_RS14060	COG3615	Tellurite resistance protein tehB
HV311_RS14070	COG3443	Belongs to the bacterial solute-binding protein 9 family
HV311_RS14085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HV311_RS14090	COG0601	transmembrane transport
HV311_RS14095	COG0747	negative chemotaxis
HV311_RS14100	COG4771	TonB-dependent receptor
HV311_RS14120	COG1956	GAF domain-containing protein
HV311_RS14125	COG2995	paraquat-inducible protein a
HV311_RS14130	COG3008	intermembrane lipid transfer
HV311_RS14225	COG4386	tail sheath protein
HV311_RS14265	COG0616	signal peptide processing
HV311_RS14310	COG3772	lysozyme
HV311_RS14325	COG0484	heat shock protein binding
HV311_RS14400	COG1484	DNA-dependent DNA replication
HV311_RS14455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV311_RS14455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV311_RS14475	COG0582	viral genome integration into host DNA
HV311_RS14485	COG1276	copper resistance
HV311_RS14490	COG2372	response to copper ion
HV311_RS14500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV311_RS14505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV311_RS14510	COG1770	oligopeptidase
HV311_RS14515	COG2979	Protein of unknown function (DUF533)
HV311_RS14525	COG3141	response to X-ray
HV311_RS14535	COG0800	Aldolase
HV311_RS14540	COG0129	dihydroxy-acid dehydratase activity
HV311_RS14545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HV311_RS14550	COG1737	Transcriptional regulator
HV311_RS14560	COG1560	Kdo2-lipid A biosynthetic process
HV311_RS14565	COG0739	heme binding
HV311_RS14570	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HV311_RS14580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HV311_RS14595	COG2850	peptidyl-arginine hydroxylation
HV311_RS14620	COG3459	Glycosyltransferase 36 associated
HV311_RS14645	COG1289	transmembrane transporter activity
HV311_RS14660	COG1278	Cold shock
HV311_RS14675	COG1177	transmembrane transport
HV311_RS14685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HV311_RS14695	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV311_RS14700	COG1136	(ABC) transporter
HV311_RS14705	COG4591	ABC-type transport system involved in lipoprotein release permease component
HV311_RS14710	COG4763	Acyl-transferase
HV311_RS14715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HV311_RS14720	COG1376	ErfK ybiS ycfS ynhG family protein
HV311_RS14720	COG1388	LysM domain
HV311_RS14730	COG1309	transcriptional regulator
HV311_RS14740	COG3134	Outer membrane lipoprotein
HV311_RS14745	COG1252	NADH dehydrogenase
HV311_RS14770	COG5633	Lipoprotein
HV311_RS14775	COG0537	adenosine 5'-monophosphoramidase activity
HV311_RS14780	COG4773	Receptor
HV311_RS14790	COG0534	Mate efflux family protein
HV311_RS14800	COG0583	DNA-binding transcription factor activity
HV311_RS14820	COG0582	viral genome integration into host DNA
HV311_RS14920	COG0456	acetyltransferase
HV311_RS15025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV311_RS15145	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS15150	COG2814	Major facilitator Superfamily
HV311_RS15155	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV311_RS15160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HV311_RS15165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV311_RS15170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HV311_RS15175	COG2188	Transcriptional regulator
HV311_RS15180	COG1064	alcohol dehydrogenase
HV311_RS15185	COG1882	Formate acetyltransferase
HV311_RS15195	COG3716	PTS system mannose fructose sorbose family IID component
HV311_RS15200	COG3715	PTS system
HV311_RS15215	COG0561	phosphatase activity
HV311_RS15225	COG1024	Enoyl-CoA hydratase
HV311_RS15240	COG2188	Transcriptional regulator
HV311_RS15245	COG0561	phosphatase activity
HV311_RS15250	COG3423	Transcriptional regulator
HV311_RS15260	COG0477	Major facilitator Superfamily
HV311_RS15265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HV311_RS15270	COG0006	proline dipeptidase activity
HV311_RS15280	COG0084	hydrolase, TatD family'
HV311_RS15285	COG0470	DNA polymerase III
HV311_RS15295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HV311_RS15300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV311_RS15315	COG3188	usher protein
HV311_RS15320	COG3539	Fimbrial protein
HV311_RS15325	COG3539	Fimbrial protein
HV311_RS15335	COG3121	Chaperone
HV311_RS15340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HV311_RS15375	COG1399	metal-binding, possibly nucleic acid-binding protein
HV311_RS15385	COG0564	pseudouridine synthase activity
HV311_RS15390	COG1530	ribonuclease E activity
HV311_RS15420	COG4786	Flagellar basal body rod
HV311_RS15425	COG4787	bacterial-type flagellum-dependent cell motility
HV311_RS15440	COG1558	bacterial-type flagellum-dependent cell motility
HV311_RS15480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HV311_RS15520	COG3038	cytochrome b561
HV311_RS15535	COG1560	Kdo2-lipid A biosynthetic process
HV311_RS15550	COG5645	(Lipo)protein
HV311_RS15570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV311_RS15625	COG3381	protein complex oligomerization
HV311_RS15650	COG1702	phosphate starvation-inducible protein PhoH
HV311_RS15675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HV311_RS15680	COG0506	proline dehydrogenase activity
HV311_RS15680	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV311_RS15680	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV311_RS15685	COG3755	Protein conserved in bacteria
HV311_RS15690	COG1309	transcriptional regulator
HV311_RS15700	COG3729	General stress protein
HV311_RS15720	COG0640	Transcriptional regulator
HV311_RS15730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HV311_RS15735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HV311_RS15735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV311_RS15785	COG0813	purine-nucleoside phosphorylase activity
HV311_RS15810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS15815	COG1120	ATPase activity
HV311_RS15830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HV311_RS15830	COG2857	Cytochrome c1
HV311_RS15870	COG4166	transmembrane transport
HV311_RS15875	COG0670	Belongs to the BI1 family
HV311_RS15915	COG2920	part of a sulfur-relay system
HV311_RS15940	COG1832	CoA-binding protein
HV311_RS15955	COG0210	DNA helicase
HV311_RS15960	COG3304	Inner membrane component domain
HV311_RS15965	COG1289	transmembrane transporter activity
HV311_RS15970	COG3070	regulator of competence-specific genes
HV311_RS15990	COG1067	ATP-dependent peptidase activity
HV311_RS16000	COG3130	regulation of translation
HV311_RS16005	COG3009	Protein conserved in bacteria
HV311_RS16010	COG3008	intermembrane lipid transfer
HV311_RS16010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HV311_RS16015	COG2995	paraquat-inducible protein a
HV311_RS16020	COG0488	(ABC) transporter
HV311_RS16030	COG3217	Mosc domain protein beta barrel domain protein
HV311_RS16030	COG0633	Ferredoxin
HV311_RS16045	COG0431	NADPH-dependent FMN reductase
HV311_RS16050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HV311_RS16060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV311_RS16070	COG0308	aminopeptidase N
HV311_RS16090	COG1448	Aminotransferase
HV311_RS16095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HV311_RS16100	COG3108	Peptidase M15
HV311_RS16105	COG2989	Protein conserved in bacteria
HV311_RS16115	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
HV311_RS16125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HV311_RS16130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HV311_RS16135	COG3173	Aminoglycoside phosphotransferase
HV311_RS16150	COG3214	Protein conserved in bacteria
HV311_RS16165	COG2333	competence protein COMEC
HV311_RS16165	COG0658	competence protein
HV311_RS16170	COG0776	regulation of translation
HV311_RS16175	COG0539	negative regulation of cytoplasmic translation
HV311_RS16195	COG2323	membrane
HV311_RS16200	COG1944	ATP diphosphatase activity
HV311_RS16205	COG2116	formate transmembrane transporter activity
HV311_RS16210	COG1882	Formate acetyltransferase
HV311_RS16215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV311_RS16235	COG3959	Transketolase, thiamine diphosphate binding domain
HV311_RS16240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HV311_RS16245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS16255	COG1335	isochorismatase
HV311_RS16260	COG3302	dmso reductase anchor subunit
HV311_RS16265	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS16270	COG0243	molybdopterin cofactor binding
HV311_RS16280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HV311_RS16300	COG0492	ferredoxin-NADP+ reductase activity
HV311_RS16305	COG4988	ABC transporter
HV311_RS16310	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HV311_RS16325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HV311_RS16330	COG0583	DNA-binding transcription factor activity
HV311_RS16340	COG1335	isochorismatase
HV311_RS16350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HV311_RS16360	COG1177	transmembrane transport
HV311_RS16365	COG1176	ABC-type spermidine putrescine transport system, permease component I
HV311_RS16370	COG3842	ATPase activity
HV311_RS16375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HV311_RS16420	COG3226	Transcriptional regulator
HV311_RS16425	COG0738	Major facilitator superfamily
HV311_RS16430	COG0561	phosphatase activity
HV311_RS16440	COG2814	Major facilitator Superfamily
HV311_RS16445	COG0671	phosphoesterase, PA-phosphatase related
HV311_RS16450	COG1349	DNA-binding transcription factor activity
HV311_RS16455	COG1686	Belongs to the peptidase S11 family
HV311_RS16460	COG0625	glutathione transferase activity
HV311_RS16465	COG2133	pyrroloquinoline quinone binding
HV311_RS16555	COG1446	asparaginase
HV311_RS16565	COG0303	'Molybdopterin
HV311_RS16570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV311_RS16575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HV311_RS16580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV311_RS16585	COG1882	Formate acetyltransferase
HV311_RS16590	COG0561	phosphatase activity
HV311_RS16605	COG0488	(ABC) transporter
HV311_RS16610	COG1376	ErfK ybiS ycfS ynhG family protein
HV311_RS16615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HV311_RS16630	COG2194	sulfuric ester hydrolase activity
HV311_RS16635	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HV311_RS16650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HV311_RS16655	COG0765	amino acid transport
HV311_RS16660	COG1126	abc transporter atp-binding protein
HV311_RS16665	COG0668	transmembrane transport
HV311_RS16680	COG4774	siderophore transport
HV311_RS16690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HV311_RS16700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
HV311_RS16705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HV311_RS16715	COG0513	Belongs to the DEAD box helicase family
HV311_RS16720	COG1309	transcriptional regulator
HV311_RS16730	COG1131	(ABC) transporter
HV311_RS16735	COG0842	Transport permease protein
HV311_RS16740	COG0842	Transport permease protein
HV311_RS16750	COG3568	Endonuclease Exonuclease Phosphatase
HV311_RS16755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HV311_RS16760	COG0392	lysyltransferase activity
HV311_RS16765	COG0670	Belongs to the BI1 family
HV311_RS16770	COG0314	molybdopterin synthase activity
HV311_RS16775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HV311_RS16785	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV311_RS16800	COG1757	Na H antiporter
HV311_RS16805	COG0626	cystathionine gamma-synthase activity
HV311_RS16820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HV311_RS16865	COG1881	PFAM PEBP family protein
HV311_RS16895	COG4677	pectinesterase activity
HV311_RS16900	COG2165	general secretion pathway protein
HV311_RS16915	COG4796	Type ii and iii secretion system protein
HV311_RS16935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV311_RS16940	COG1459	type II secretion system
HV311_RS16945	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HV311_RS16950	COG0741	lytic transglycosylase activity
HV311_RS16950	COG0739	heme binding
HV311_RS16950	COG1196	nuclear chromosome segregation
HV311_RS16965	COG0561	phosphatase activity
HV311_RS16975	COG4149	molybdate abc transporter
HV311_RS16980	COG0725	ABC transporter, periplasmic molybdate-binding protein
HV311_RS16990	COG2005	Transcriptional regulator
HV311_RS16990	COG3585	molybdate ion transport
HV311_RS16995	COG1119	ATPase activity
HV311_RS17000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HV311_RS17005	COG1085	galactose-1-phosphate uridylyltransferase
HV311_RS17015	COG2017	converts alpha-aldose to the beta-anomer
HV311_RS17025	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HV311_RS17035	COG1230	cation diffusion facilitator family transporter
HV311_RS17040	COG3201	nicotinamide mononucleotide transporter
HV311_RS17075	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HV311_RS17080	COG2885	chlorophyll binding
HV311_RS17090	COG3064	Membrane
HV311_RS17095	COG0848	biopolymer transport protein
HV311_RS17100	COG0811	peptide transport
HV311_RS17105	COG0824	Thioesterase
HV311_RS17110	COG3790	cyd operon protein YbgE
HV311_RS17115	COG4890	Cyd operon protein YbgT
HV311_RS17120	COG1294	oxidase, subunit
HV311_RS17125	COG1271	oxidase subunit
HV311_RS17130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HV311_RS17140	COG4865	methylaspartate mutase activity
HV311_RS17145	COG3799	methylaspartate ammonia-lyase activity
HV311_RS17160	COG1301	dicarboxylic acid transport
HV311_RS17170	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS17170	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS17180	COG0583	DNA-binding transcription factor activity
HV311_RS17185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HV311_RS17185	COG1648	precorrin-2 dehydrogenase activity
HV311_RS17195	COG3395	kinase activity
HV311_RS17200	COG0235	Class ii aldolase
HV311_RS17205	COG1349	DNA-binding transcription factor activity
HV311_RS17210	COG3622	Belongs to the hyi family
HV311_RS17215	COG3246	L-lysine catabolic process to acetate
HV311_RS17235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HV311_RS17245	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV311_RS17250	COG0567	Dehydrogenase, E1 component
HV311_RS17255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV311_RS17260	COG1053	succinate dehydrogenase
HV311_RS17265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HV311_RS17270	COG2009	succinate dehydrogenase
HV311_RS17280	COG3180	Ammonia monooxygenase
HV311_RS17310	COG1984	allophanate hydrolase subunit 2
HV311_RS17315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HV311_RS17330	COG5464	transposase or invertase
HV311_RS17365	COG2205	protein histidine kinase activity
HV311_RS17370	COG0745	RESPONSE REGULATOR receiver
HV311_RS17380	COG1982	Orn Lys Arg decarboxylase major
HV311_RS17385	COG0531	amino acid
HV311_RS17390	COG0033	Phosphoglucomutase
HV311_RS17395	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
HV311_RS17400	COG0596	Alpha beta hydrolase
HV311_RS17410	COG0716	FMN binding
HV311_RS17420	COG0735	belongs to the Fur family
HV311_RS17425	COG0583	DNA-binding transcription factor activity
HV311_RS17430	COG1053	succinate dehydrogenase
HV311_RS17455	COG1609	Transcriptional regulator
HV311_RS17465	COG1653	transport
HV311_RS17475	COG1263	PTS System
HV311_RS17475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS17475	COG2190	(PTS) system
HV311_RS17485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HV311_RS17490	COG1940	carbohydrate kinase activity
HV311_RS17490	COG1846	Transcriptional regulator
HV311_RS17495	COG0647	UMP catabolic process
HV311_RS17500	COG0367	asparagine synthase
HV311_RS17540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HV311_RS17550	COG1702	phosphate starvation-inducible protein PhoH
HV311_RS17555	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HV311_RS17575	COG0765	amino acid transport
HV311_RS17580	COG0765	amino acid transport
HV311_RS17585	COG1126	abc transporter atp-binding protein
HV311_RS17595	COG2888	peptidyl-tyrosine sulfation
HV311_RS17610	COG1466	dna polymerase III delta subunit
HV311_RS17630	COG0799	negative regulation of ribosome biogenesis
HV311_RS17640	COG0768	penicillin binding
HV311_RS17645	COG0772	Belongs to the SEDS family
HV311_RS17650	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV311_RS17655	COG1686	Belongs to the peptidase S11 family
HV311_RS17680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV311_RS17700	COG3069	C4-dicarboxylate transmembrane transporter activity
HV311_RS17705	COG4565	transcriptional regulatory protein
HV311_RS17710	COG3290	protein histidine kinase activity
HV311_RS17715	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HV311_RS17725	COG2301	Belongs to the HpcH HpaI aldolase family
HV311_RS17730	COG3051	citrate lyase alpha subunit
HV311_RS17745	COG0471	metal ion transport
HV311_RS17750	COG3719	Belongs to the RNase T2 family
HV311_RS17765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HV311_RS17775	COG3634	alkyl hydroperoxide reductase activity
HV311_RS17785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HV311_RS17790	COG0583	DNA-binding transcription factor activity
HV311_RS17795	COG3969	phosphoadenosine phosphosulfate
HV311_RS17800	COG1475	DNA binding
HV311_RS17805	COG0436	Aminotransferase
HV311_RS17810	COG0371	Dehydrogenase
HV311_RS17815	COG2879	small protein
HV311_RS17820	COG1966	Carbon starvation protein
HV311_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS17835	COG1535	isochorismatase
HV311_RS17835	COG3433	isochorismatase activity
HV311_RS17840	COG1021	2,3-dihydroxybenzoate-AMP ligase
HV311_RS17845	COG1169	isochorismate synthase
HV311_RS17850	COG4592	Periplasmic binding protein
HV311_RS17860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS17865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS17870	COG1120	ATPase activity
HV311_RS17875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HV311_RS17875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HV311_RS17880	COG3251	PFAM MbtH domain protein
HV311_RS17885	COG2382	esterase
HV311_RS17890	COG4771	TonB-dependent receptor
HV311_RS17930	COG2315	Protein conserved in bacteria
HV311_RS17940	COG0668	transmembrane transport
HV311_RS17960	COG2211	Major facilitator Superfamily
HV311_RS17965	COG1113	amino acid transport
HV311_RS17985	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS17995	COG5001	Diguanylate cyclase
HV311_RS17995	COG3300	MHYT domain
HV311_RS18010	COG3059	membrane
HV311_RS18020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV311_RS18025	COG2207	Transcriptional regulator
HV311_RS18030	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV311_RS18035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS18040	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS18045	COG1538	Outer membrane efflux protein
HV311_RS18050	COG0745	RESPONSE REGULATOR receiver
HV311_RS18055	COG5002	protein histidine kinase activity
HV311_RS18075	COG0321	lipoyl(octanoyl) transferase activity
HV311_RS18075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV311_RS18085	COG3005	denitrification pathway
HV311_RS18105	COG3005	denitrification pathway
HV311_RS18110	COG0745	RESPONSE REGULATOR receiver
HV311_RS18115	COG1879	ABC-type sugar transport system periplasmic component
HV311_RS18125	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS18195	COG2501	S4 domain
HV311_RS18200	COG1988	membrane-bound metal-dependent
HV311_RS18210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HV311_RS18220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HV311_RS18225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HV311_RS18235	COG2011	ABC-type metal ion transport system permease component
HV311_RS18245	COG1464	Belongs to the NlpA lipoprotein family
HV311_RS18265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HV311_RS18270	COG4181	ATPase activity
HV311_RS18275	COG2755	lipolytic protein G-D-S-L family
HV311_RS18280	COG0300	oxidoreductase activity
HV311_RS18285	COG3118	belongs to the thioredoxin family
HV311_RS18290	COG0390	transport system, permease component
HV311_RS18295	COG4619	ABC transporter
HV311_RS18300	COG0330	HflC and HflK could
HV311_RS18305	COG1585	Membrane protein implicated in regulation of membrane protease activity
HV311_RS18325	COG4771	TonB-dependent receptor
HV311_RS18330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV311_RS18340	COG3721	Heme iron utilization protein
HV311_RS18350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HV311_RS18365	COG3735	TraB family
HV311_RS18370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV311_RS18380	COG2223	nitrite transmembrane transporter activity
HV311_RS18385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HV311_RS18385	COG4651	solute:proton antiporter activity
HV311_RS18390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS18435	COG2832	Protein of unknown function (DUF454)
HV311_RS18440	COG3923	Primosomal replication protein n
HV311_RS18450	COG1196	nuclear chromosome segregation
HV311_RS18450	COG3264	Mechanosensitive ion channel
HV311_RS18455	COG1309	transcriptional regulator
HV311_RS18460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HV311_RS18465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV311_RS18480	COG0110	maltose O-acetyltransferase activity
HV311_RS18500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV311_RS18505	COG5507	3-demethylubiquinone-9 3-methyltransferase
HV311_RS18510	COG2364	Membrane
HV311_RS18515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV311_RS18535	COG3695	enzyme binding
HV311_RS18540	COG3126	Type III secretion system lipoprotein chaperone (YscW)
HV311_RS18545	COG1946	Acyl-CoA thioesterase
HV311_RS18550	COG0004	ammonium transporteR
HV311_RS18555	COG0347	Belongs to the P(II) protein family
HV311_RS18560	COG1132	(ABC) transporter
HV311_RS18565	COG1132	(ABC) transporter
HV311_RS18570	COG1522	sequence-specific DNA binding
HV311_RS18585	COG4533	DNA binding
HV311_RS18595	COG0824	Thioesterase
HV311_RS18600	COG1555	photosystem II stabilization
HV311_RS18605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV311_RS18610	COG0776	regulation of translation
HV311_RS18615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HV311_RS18635	COG0271	Belongs to the BolA IbaG family
HV311_RS18640	COG3056	Lipoprotein
HV311_RS18645	COG2223	nitrite transmembrane transporter activity
HV311_RS18650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HV311_RS18655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HV311_RS18660	COG1845	cytochrome c oxidase, subunit III
HV311_RS18665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HV311_RS18690	COG2814	Major facilitator Superfamily
HV311_RS18710	COG3302	dmso reductase anchor subunit
HV311_RS18715	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS18720	COG0243	molybdopterin cofactor binding
HV311_RS18740	COG0142	geranyltranstransferase activity
HV311_RS18750	COG0667	Aldo Keto reductase
HV311_RS18755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HV311_RS18760	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HV311_RS18775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV311_RS18775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HV311_RS18785	COG4238	major outer membrane lipoprotein
HV311_RS18790	COG3248	Nucleoside-binding outer membrane protein
HV311_RS18805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV311_RS18810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HV311_RS18815	COG1862	Preprotein translocase
HV311_RS18825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HV311_RS18835	COG0450	alkyl hydroperoxide reductase
HV311_RS18850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HV311_RS18860	COG1335	isochorismatase
HV311_RS18865	COG0583	DNA-binding transcription factor activity
HV311_RS18870	COG0366	Alpha amylase catalytic
HV311_RS18885	COG5002	protein histidine kinase activity
HV311_RS18895	COG0420	3'-5' exonuclease activity
HV311_RS18900	COG0419	ATPase involved in DNA repair
HV311_RS18905	COG2814	Major facilitator Superfamily
HV311_RS18910	COG1940	carbohydrate kinase activity
HV311_RS18925	COG4126	flavin adenine dinucleotide binding
HV311_RS18945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HV311_RS18950	COG3706	GGDEF domain
HV311_RS18960	COG1785	Belongs to the alkaline phosphatase family
HV311_RS18975	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV311_RS18995	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HV311_RS19000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HV311_RS19005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV311_RS19010	COG3468	outer membrane autotransporter barrel domain protein
HV311_RS19015	COG0113	porphobilinogen synthase activity
HV311_RS19020	COG2175	clavaminate synthase activity
HV311_RS19025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HV311_RS19030	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HV311_RS19035	COG4521	taurine ABC transporter
HV311_RS19050	COG2271	Major facilitator Superfamily
HV311_RS19055	COG1840	ABC-type Fe3 transport system, periplasmic component
HV311_RS19065	COG3842	ATPase activity
HV311_RS19070	COG2040	homocysteine
HV311_RS19075	COG0833	amino acid
HV311_RS19080	COG2814	Major facilitator Superfamily
HV311_RS19115	COG1414	Transcriptional regulator
HV311_RS19185	COG3210	domain, Protein
HV311_RS19205	COG1609	Transcriptional regulator
HV311_RS19230	COG2079	MmgE PrpD family protein
HV311_RS19235	COG0372	Belongs to the citrate synthase family
HV311_RS19245	COG3829	transcription factor binding
HV311_RS19255	COG1280	lysine exporter protein (LysE YggA)
HV311_RS19260	COG3706	GGDEF domain
HV311_RS19265	COG0348	domain, Protein
HV311_RS19285	COG0840	transmembrane signaling receptor activity
HV311_RS19300	COG3069	C4-dicarboxylate transmembrane transporter activity
HV311_RS19305	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV311_RS19315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HV311_RS19320	COG0693	protein deglycase activity
HV311_RS19325	COG0531	amino acid
HV311_RS19330	COG0174	glutamine synthetase
HV311_RS19335	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HV311_RS19340	COG1917	Cupin 2, conserved barrel domain protein
HV311_RS19340	COG1396	sequence-specific DNA binding
HV311_RS19345	COG1012	belongs to the aldehyde dehydrogenase family
HV311_RS19350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HV311_RS19365	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
HV311_RS19370	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HV311_RS19375	COG1999	signal sequence binding
HV311_RS19380	COG1773	rubredoxin
HV311_RS19385	COG1271	oxidase subunit
HV311_RS19390	COG1294	oxidase, subunit
HV311_RS19410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HV311_RS19420	COG0732	type I restriction modification DNA specificity domain
HV311_RS19425	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HV311_RS19445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HV311_RS19460	COG0582	viral genome integration into host DNA
HV311_RS19495	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS19505	COG3344	reverse transcriptase
HV311_RS19545	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS19560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HV311_RS19580	COG2003	Belongs to the UPF0758 family
HV311_RS19710	COG0494	nUDIX hydrolase
HV311_RS19750	COG3772	lysozyme
HV311_RS19830	COG0305	Participates in initiation and elongation during chromosome replication
HV311_RS19885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV311_RS19920	COG0863	Belongs to the N(4) N(6)-methyltransferase family
HV311_RS19935	COG0582	viral genome integration into host DNA
HV311_RS19950	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV311_RS19995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HV311_RS20005	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HV311_RS20030	COG2195	Cleaves the N-terminal amino acid of tripeptides
HV311_RS20050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HV311_RS20055	COG1191	sigma factor activity
HV311_RS20080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HV311_RS20105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HV311_RS20110	COG4786	Flagellar basal body rod
HV311_RS20110	COG1256	bacterial-type flagellum assembly
HV311_RS20130	COG4786	Flagellar basal body rod
HV311_RS20135	COG4787	bacterial-type flagellum-dependent cell motility
HV311_RS20150	COG1558	bacterial-type flagellum-dependent cell motility
HV311_RS20195	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HV311_RS20215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HV311_RS20225	COG1677	Flagellar hook-basal body complex protein FliE
HV311_RS20250	COG1987	bacterial-type flagellum assembly
HV311_RS20255	COG1684	flagellar biosynthetic protein fliR
HV311_RS20270	COG0791	NLP P60 protein
HV311_RS20275	COG3034	peptidoglycan biosynthetic process
HV311_RS20280	COG0121	glutamine amidotransferase
HV311_RS20290	COG1960	acyl-CoA dehydrogenase activity
HV311_RS20295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HV311_RS20305	COG2200	EAL domain
HV311_RS20320	COG3539	Fimbrial protein
HV311_RS20330	COG3121	Chaperone
HV311_RS20335	COG3188	usher protein
HV311_RS20345	COG3539	Fimbrial protein
HV311_RS20365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HV311_RS20375	COG2226	methyltransferase
HV311_RS20385	COG1388	LysM domain
HV311_RS20385	COG0741	lytic transglycosylase activity
HV311_RS20390	COG2226	methyltransferase
HV311_RS20400	COG2814	Major facilitator Superfamily
HV311_RS20405	COG0583	DNA-binding transcription factor activity
HV311_RS20440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HV311_RS20450	COG2011	ABC-type metal ion transport system permease component
HV311_RS20455	COG1464	Belongs to the NlpA lipoprotein family
HV311_RS20465	COG1720	tRNA m6t6A37 methyltransferase activity
HV311_RS20475	COG0791	NLP P60 protein
HV311_RS20480	COG3015	lipoprotein NlpE involved in copper resistance
HV311_RS20485	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HV311_RS20500	COG4568	rho-dependent transcription termination
HV311_RS20510	COG0346	lactoylglutathione lyase activity
HV311_RS20515	COG1982	Orn Lys Arg decarboxylase major
HV311_RS20550	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HV311_RS20555	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
HV311_RS20570	COG0575	Belongs to the CDS family
HV311_RS20580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HV311_RS20625	COG3835	regulator
HV311_RS20650	COG2860	membrane
HV311_RS20675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HV311_RS20680	COG1120	ATPase activity
HV311_RS20685	COG4774	siderophore transport
HV311_RS20690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HV311_RS20695	COG1643	Atp-dependent helicase
HV311_RS20700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HV311_RS20720	COG0617	tRNA 3'-terminal CCA addition
HV311_RS20725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HV311_RS20745	COG0726	polysaccharide deacetylase
HV311_RS20750	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS20755	COG0842	Transport permease protein
HV311_RS20760	COG1131	(ABC) transporter
HV311_RS20765	COG0288	reversible hydration of carbon dioxide
HV311_RS20770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HV311_RS20775	COG4993	Dehydrogenase
HV311_RS20795	COG1609	Transcriptional regulator
HV311_RS20800	COG2814	Major facilitator Superfamily
HV311_RS20835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HV311_RS20840	COG0508	dehydrogenase complex catalyzes the overall conversion of
HV311_RS20845	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HV311_RS20860	COG2211	Major facilitator Superfamily
HV311_RS20865	COG3940	Belongs to the glycosyl hydrolase 43 family
HV311_RS20870	COG3725	Membrane protein required for beta-lactamase induction
HV311_RS20885	COG4969	Belongs to the N-Me-Phe pilin family
HV311_RS20890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HV311_RS20895	COG1459	type II secretion system
HV311_RS20905	COG0237	dephospho-CoA kinase activity
HV311_RS20920	COG0494	nUDIX hydrolase
HV311_RS20940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HV311_RS20945	COG0849	cell division
HV311_RS20955	COG1181	Belongs to the D-alanine--D-alanine ligase family
HV311_RS20970	COG0772	Belongs to the SEDS family
HV311_RS20975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HV311_RS20985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HV311_RS20990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HV311_RS20995	COG0768	penicillin binding
HV311_RS21025	COG0028	Belongs to the TPP enzyme family
HV311_RS21060	COG2814	Major facilitator Superfamily
HV311_RS21080	COG1178	ABC-type Fe3 transport system permease component
HV311_RS21090	COG0586	Pfam SNARE associated Golgi protein
HV311_RS21110	COG0235	Class ii aldolase
HV311_RS21120	COG0417	DNA replication proofreading
HV311_RS21130	COG0564	pseudouridine synthase activity
HV311_RS21190	COG2271	Major facilitator Superfamily
HV311_RS21200	COG0644	oxidoreductase
HV311_RS21250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HV311_RS21255	COG0505	Belongs to the CarA family
HV311_RS21265	COG1609	Transcriptional regulator
HV311_RS21280	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS21280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS21285	COG3715	PTS system
HV311_RS21290	COG3716	PTS system mannose fructose sorbose family IID component
HV311_RS21305	COG2140	Oxalate decarboxylase
HV311_RS21320	COG1047	Peptidyl-prolyl cis-trans
HV311_RS21335	COG0196	riboflavin kinase activity
HV311_RS21345	COG0583	DNA-binding transcription factor activity
HV311_RS21380	COG0641	radical SAM
HV311_RS21385	COG3119	arylsulfatase activity
HV311_RS21420	COG0443	Heat shock 70 kDa protein
HV311_RS21425	COG1584	GPR1 FUN34 yaaH family protein
HV311_RS21435	COG0521	Mo-molybdopterin cofactor biosynthetic process
HV311_RS21445	COG1115	amino acid carrier protein
HV311_RS21455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HV311_RS21465	COG0460	homoserine dehydrogenase
HV311_RS21465	COG0527	aspartate kinase activity
HV311_RS21475	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
HV311_RS21485	COG0745	RESPONSE REGULATOR receiver
HV311_RS21490	COG4452	Inner membrane protein CreD
HV311_RS21495	COG2205	protein histidine kinase activity
HV311_RS21500	COG0745	RESPONSE REGULATOR receiver
HV311_RS21505	COG3045	CreA protein
HV311_RS21510	COG3708	Transcriptional regulator
HV311_RS21510	COG2207	Transcriptional regulator
HV311_RS21530	COG0741	lytic transglycosylase activity
HV311_RS21535	COG0488	(ABC) transporter
HV311_RS21550	COG0560	Phosphoserine phosphatase
HV311_RS21555	COG3726	membrane protein affecting hemolysin expression
HV311_RS21585	COG1328	CTP reductase activity
HV311_RS21590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV311_RS21595	COG0084	hydrolase, TatD family'
HV311_RS21600	COG4667	esterase of the alpha-beta hydrolase superfamily
HV311_RS21605	COG5487	UPF0391 membrane protein
HV311_RS21610	COG2823	Periplasmic or secreted lipoprotein
HV311_RS21620	COG1011	Hydrolase
HV311_RS21625	COG0456	acetyltransferase
HV311_RS21630	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
HV311_RS21660	COG3706	GGDEF domain
HV311_RS21665	COG4114	ferric iron reductase
HV311_RS21670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV311_RS21675	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HV311_RS21680	COG2197	response regulator
HV311_RS21685	COG2197	response regulator
HV311_RS21690	COG2966	Psort location CytoplasmicMembrane, score
HV311_RS21705	COG1484	DNA-dependent DNA replication
HV311_RS21725	COG1063	alcohol dehydrogenase
HV311_RS21730	COG1802	Transcriptional regulator
HV311_RS21735	COG2271	Major facilitator Superfamily
HV311_RS21745	COG0840	transmembrane signaling receptor activity
HV311_RS21750	COG1966	Carbon starvation protein
HV311_RS21755	COG2879	small protein
HV311_RS21760	COG0523	cobalamin synthesis protein
HV311_RS21780	COG1715	Restriction endonuclease
HV311_RS21815	COG1566	PFAM secretion protein HlyD family protein
HV311_RS21825	COG5457	Domain of unknown function (DUF1127)
HV311_RS21830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HV311_RS21835	COG5464	transposase or invertase
HV311_RS21835	COG5464	transposase or invertase
HV311_RS21840	COG1917	Cupin 2, conserved barrel domain protein
HV311_RS21840	COG2207	Transcriptional regulator
HV311_RS21855	COG0626	cystathionine gamma-synthase activity
HV311_RS21860	COG1301	dicarboxylic acid transport
HV311_RS21865	COG0583	DNA-binding transcription factor activity
HV311_RS21870	COG2733	membrane
HV311_RS21875	COG0477	Major facilitator Superfamily
HV311_RS21885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HV311_RS21895	COG2186	Transcriptional regulator
HV311_RS21900	COG0246	Mannitol dehydrogenase
HV311_RS21910	COG2610	gluconate transmembrane transporter activity
HV311_RS21915	COG1556	Lactate utilization protein
HV311_RS21920	COG1139	Iron-sulfur cluster binding protein
HV311_RS21925	COG0247	lactate metabolic process
HV311_RS21930	COG1620	l-lactate permease
HV311_RS21990	COG0326	Molecular chaperone. Has ATPase activity
HV311_RS22015	COG2003	Belongs to the UPF0758 family
HV311_RS22040	COG2378	regulation of single-species biofilm formation
HV311_RS22050	COG3596	GTP binding
HV311_RS22095	COG0720	synthase
HV311_RS22130	COG0514	ATP-dependent DNA helicase (RecQ)
HV311_RS22155	COG0582	viral genome integration into host DNA
HV311_RS22165	COG1064	alcohol dehydrogenase
HV311_RS22170	COG3265	gluconokinase activity
HV311_RS22175	COG1063	alcohol dehydrogenase
HV311_RS22180	COG1028	Short-chain dehydrogenase reductase Sdr
HV311_RS22185	COG2610	gluconate transmembrane transporter activity
HV311_RS22190	COG1609	Transcriptional regulator
HV311_RS22195	COG0433	COG0433 Predicted ATPase
HV311_RS22200	COG0795	lipopolysaccharide-transporting ATPase activity
HV311_RS22205	COG0795	lipopolysaccharide-transporting ATPase activity
HV311_RS22215	COG2927	DNA polymerase III (CHI subunit)
HV311_RS22220	COG0525	valine-tRNA ligase activity
HV311_RS22250	COG2731	YhcH YjgK YiaL family protein
HV311_RS22265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HV311_RS22270	COG1288	antiporter activity
HV311_RS22275	COG1438	arginine binding
HV311_RS22325	COG1263	PTS System
HV311_RS22325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HV311_RS22330	COG0366	Alpha amylase catalytic
HV311_RS22340	COG0602	queuosine metabolic process
HV311_RS22345	COG3711	transcriptional antiterminator
HV311_RS22345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS22360	COG3964	amidohydrolase
HV311_RS22395	COG0312	modulator of DNA gyrase
HV311_RS22405	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HV311_RS22410	COG0363	glucosamine-6-phosphate deaminase activity
HV311_RS22415	COG1486	melibiose metabolic process
HV311_RS22420	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HV311_RS22420	COG0517	IMP dehydrogenase activity
HV311_RS22425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HV311_RS22435	COG0840	transmembrane signaling receptor activity
HV311_RS22440	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS22445	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS22450	COG1129	ABC transporter
HV311_RS22455	COG1879	ABC-type sugar transport system periplasmic component
HV311_RS22465	COG3391	amine dehydrogenase activity
HV311_RS22470	COG4771	TonB-dependent receptor
HV311_RS22475	COG2105	PFAM AIG2 family protein
HV311_RS22480	COG2911	Protein conserved in bacteria
HV311_RS22485	COG0729	surface antigen
HV311_RS22495	COG1253	flavin adenine dinucleotide binding
HV311_RS22505	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
HV311_RS22510	COG1218	3'(2'),5'-bisphosphate nucleotidase
HV311_RS22520	COG1733	regulation of RNA biosynthetic process
HV311_RS22525	COG0702	epimerase
HV311_RS22535	COG0697	spore germination
HV311_RS22540	COG0840	transmembrane signaling receptor activity
HV311_RS22550	COG1113	amino acid transport
HV311_RS22555	COG0545	Peptidyl-prolyl cis-trans isomerase
HV311_RS22560	COG3061	Opacity-associated protein A
HV311_RS22575	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HV311_RS22590	COG0730	response to heat
HV311_RS22640	COG1073	alpha beta
HV311_RS22645	COG3650	response to hydrogen peroxide
HV311_RS22655	COG1960	acyl-CoA dehydrogenase activity
HV311_RS22660	COG0754	glutathionylspermidine amidase activity
HV311_RS22665	COG5463	Belongs to the UPF0441 family
HV311_RS22670	COG3766	membrane
HV311_RS22685	COG1842	Phage shock protein A
HV311_RS22690	COG3789	protein conserved in bacteria
HV311_RS22695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HV311_RS22700	COG0557	exoribonuclease II activity
HV311_RS22715	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
HV311_RS22720	COG0330	HflC and HflK could
HV311_RS22725	COG0330	HflC and HflK could
HV311_RS22730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HV311_RS22735	COG1923	regulation of RNA biosynthetic process
HV311_RS22750	COG0860	N-Acetylmuramoyl-L-alanine amidase
HV311_RS22755	COG0802	atpase or kinase
HV311_RS22760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HV311_RS22760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HV311_RS22765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HV311_RS22800	COG1511	domain protein
HV311_RS22800	COG3264	Mechanosensitive ion channel
HV311_RS22825	COG1053	succinate dehydrogenase
HV311_RS22830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HV311_RS22885	COG1509	lysine 2,3-aminomutase activity
HV311_RS22910	COG0531	amino acid
HV311_RS22915	COG3030	protein affecting phage T7 exclusion by the F plasmid
HV311_RS22920	COG1027	Aspartate ammonia-lyase
HV311_RS22925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV311_RS22940	COG1309	transcriptional regulator
HV311_RS22970	COG3290	protein histidine kinase activity
HV311_RS22975	COG4565	transcriptional regulatory protein
HV311_RS22985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
HV311_RS22990	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS22990	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HV311_RS22995	COG3647	Membrane
HV311_RS23005	COG2211	Major facilitator Superfamily
HV311_RS23015	COG2169	Transcriptional regulator
HV311_RS23020	COG1982	Orn Lys Arg decarboxylase major
HV311_RS23025	COG2207	Transcriptional regulator
HV311_RS23030	COG0531	amino acid
HV311_RS23075	COG2824	Alkylphosphonate utilization operon protein PhnA
HV311_RS23080	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HV311_RS23085	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HV311_RS23090	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
HV311_RS23095	COG3639	organic phosphonate transmembrane transporter activity
HV311_RS23100	COG2188	Transcriptional regulator
HV311_RS23105	COG3624	Phosphonate C-P lyase system protein PhnG
HV311_RS23110	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
HV311_RS23115	COG3626	phosphonate metabolism
HV311_RS23120	COG3627	carbon phosphorus lyase activity
HV311_RS23125	COG4107	phosphonate C-P lyase system protein PhnK
HV311_RS23130	COG4778	phosphonate C-P lyase system protein PhnL
HV311_RS23135	COG3454	Phosphonate metabolism
HV311_RS23140	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
HV311_RS23145	COG0456	acetyltransferase
HV311_RS23150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HV311_RS23165	COG1129	ABC transporter
HV311_RS23170	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS23205	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
HV311_RS23210	COG1301	dicarboxylic acid transport
HV311_RS23215	COG4235	cytochrome complex assembly
HV311_RS23220	COG3088	subunit of a heme lyase
HV311_RS23225	COG1138	Cytochrome C-type biogenesis protein
HV311_RS23230	COG3301	Polysulphide reductase, NrfD
HV311_RS23235	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS23240	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HV311_RS23255	COG3162	membrane
HV311_RS23265	COG1346	cytolysis
HV311_RS23270	COG1380	Effector of murein hydrolase LrgA
HV311_RS23275	COG0583	DNA-binding transcription factor activity
HV311_RS23280	COG0025	NhaP-type Na H and K H
HV311_RS23285	COG2252	PERMEase
HV311_RS23290	COG0789	Transcriptional regulator
HV311_RS23300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HV311_RS23310	COG0629	single-stranded DNA binding
HV311_RS23315	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HV311_RS23320	COG2315	Protein conserved in bacteria
HV311_RS23325	COG3700	Belongs to the class B bacterial acid phosphatase family
HV311_RS23330	COG1448	Aminotransferase
HV311_RS23340	COG0305	Participates in initiation and elongation during chromosome replication
HV311_RS23355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HV311_RS23365	COG0735	belongs to the Fur family
HV311_RS23370	COG3237	CsbD-like
HV311_RS23375	COG0534	Mate efflux family protein
HV311_RS23385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HV311_RS23420	COG2182	Extracellular solute-binding protein
HV311_RS23435	COG3223	Belongs to the PsiE family
HV311_RS23440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HV311_RS23445	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HV311_RS23470	COG0527	aspartate kinase activity
HV311_RS23485	COG1187	pseudouridine synthase activity
HV311_RS23490	COG4977	sequence-specific DNA binding
HV311_RS23510	COG1410	methionine synthase
HV311_RS23510	COG0646	methionine synthase
HV311_RS23530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HV311_RS23560	COG0151	Belongs to the GarS family
HV311_RS23570	COG4191	Histidine kinase
HV311_RS23625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HV311_RS23630	COG2104	thiamine diphosphate biosynthetic process
HV311_RS23645	COG1278	Cold shock
HV311_RS23655	COG1447	Phosphotransferase system cellobiose-specific component IIA
HV311_RS23690	COG0250	Participates in transcription elongation, termination and antitermination
HV311_RS23735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HV311_RS23795	COG0583	DNA-binding transcription factor activity
HV311_RS23800	COG3979	chitinase
HV311_RS23835	COG2207	Transcriptional regulator
HV311_RS23840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS23845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HV311_RS23850	COG1882	Formate acetyltransferase
HV311_RS23855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS23860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS23865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HV311_RS23865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS23865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS23875	COG0371	Dehydrogenase
HV311_RS23885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HV311_RS23890	COG0583	DNA-binding transcription factor activity
HV311_RS23900	COG0737	Belongs to the 5'-nucleotidase family
HV311_RS23910	COG0527	aspartate kinase activity
HV311_RS23910	COG0460	homoserine dehydrogenase
HV311_RS23915	COG0626	cystathionine gamma-synthase activity
HV311_RS23925	COG2211	Major facilitator Superfamily
HV311_RS23940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HV311_RS23945	COG1609	Transcriptional regulator
HV311_RS23950	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HV311_RS23965	COG1575	Belongs to the MenA family. Type 1 subfamily
HV311_RS23985	COG3074	FtsZ-dependent cytokinesis
HV311_RS23990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HV311_RS24000	COG1494	fructose-1,6-bisphosphatase
HV311_RS24010	COG3152	Membrane
HV311_RS24035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HV311_RS24050	COG3678	ATP-independent chaperone mediated protein folding
HV311_RS24055	COG0745	RESPONSE REGULATOR receiver
HV311_RS24060	COG2205	protein histidine kinase activity
HV311_RS24065	COG2271	Major facilitator Superfamily
HV311_RS24070	COG1082	Xylose isomerase domain protein TIM barrel
HV311_RS24075	COG2188	Transcriptional regulator
HV311_RS24080	COG2258	MOSC domain
HV311_RS24085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HV311_RS24135	COG1454	alcohol dehydrogenase
HV311_RS24155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HV311_RS24165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS24170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS24170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HV311_RS24175	COG1363	Peptidase, m42
HV311_RS24180	COG3711	transcriptional antiterminator
HV311_RS24180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HV311_RS24200	COG0437	4 iron, 4 sulfur cluster binding
HV311_RS24205	COG2864	formate dehydrogenase
HV311_RS24220	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HV311_RS24230	COG3609	addiction module antidote protein, CC2985 family
HV311_RS24240	COG0456	acetyltransferase
HV311_RS24245	COG1490	D-aminoacyl-tRNA deacylase activity
HV311_RS24255	COG1011	Hydrolase
HV311_RS24260	COG1349	DNA-binding transcription factor activity
HV311_RS24265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS24275	COG3684	Belongs to the aldolase LacD family
HV311_RS24285	COG2017	converts alpha-aldose to the beta-anomer
HV311_RS24290	COG1501	Belongs to the glycosyl hydrolase 31 family
HV311_RS24320	COG3852	Histidine kinase
HV311_RS24325	COG2204	response regulator
HV311_RS24335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HV311_RS24360	COG0204	Acyl-transferase
HV311_RS24375	COG3084	Protein conserved in bacteria
HV311_RS24380	COG0746	molybdenum cofactor guanylyltransferase activity
HV311_RS24385	COG1763	Mo-molybdopterin cofactor biosynthetic process
HV311_RS24425	COG1739	Uncharacterized protein family UPF0029
HV311_RS24445	COG1609	Transcriptional regulator
HV311_RS24450	COG1940	carbohydrate kinase activity
HV311_RS24460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HV311_RS24475	COG0805	protein transport
HV311_RS24520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HV311_RS24525	COG0583	DNA-binding transcription factor activity
HV311_RS24530	COG0697	spore germination
HV311_RS24535	COG0561	phosphatase activity
HV311_RS24540	COG2267	carboxylic ester hydrolase activity
HV311_RS24545	COG1280	lysine exporter protein (LysE YggA)
HV311_RS24550	COG1280	lysine exporter protein (LysE YggA)
HV311_RS24585	COG1011	Hydrolase
HV311_RS24630	COG2959	enzyme of heme biosynthesis
HV311_RS24635	COG3071	HemY protein
HV311_RS24680	COG2244	polysaccharide biosynthetic process
HV311_RS24685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HV311_RS24690	COG0456	acetyltransferase
HV311_RS24695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HV311_RS24710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HV311_RS24715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HV311_RS24725	COG3118	belongs to the thioredoxin family
HV311_RS24745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HV311_RS24765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HV311_RS24775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HV311_RS24780	COG3978	acetolactate synthase activity
HV311_RS24800	COG3085	chromosome segregation
HV311_RS24840	COG2186	Transcriptional regulator
HV311_RS24845	COG0477	Major facilitator Superfamily
HV311_RS24850	COG1609	Transcriptional regulator
HV311_RS24855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HV311_RS24860	COG1879	ABC-type sugar transport system periplasmic component
HV311_RS24865	COG1172	Belongs to the binding-protein-dependent transport system permease family
HV311_RS24875	COG1869	D-ribose catabolic process
HV311_RS24900	COG1522	sequence-specific DNA binding
HV311_RS24905	COG0716	FMN binding
HV311_RS24920	COG3312	ion transport
HV311_RS24945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HV311_RS24955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HV311_RS24960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HV311_RS24975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HV311_RS24980	COG0573	inorganic phosphate transmembrane transporter activity
HV311_RS24985	COG0581	inorganic phosphate transmembrane transporter activity
HV311_RS24995	COG0704	Plays a role in the regulation of phosphate uptake
HV311_RS25000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HV311_RS25005	COG2252	PERMEase
HV311_RS25010	COG0431	NADPH-dependent FMN reductase
HV311_RS25015	COG2091	lysine biosynthetic process via aminoadipic acid
HV311_RS25050	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HV311_RS25155	COG0058	SHG alpha-glucan phosphorylase activity
HV311_RS25160	COG0033	Phosphoglucomutase
HV311_RS25230	COG3039	Transposase
HV311_RS25240	COG1528	Iron-storage protein
HV311_RS25250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV311_RS25290	COG0789	Transcriptional regulator
HV311_RS25305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HV311_RS25315	COG0589	response to stress
HV311_RS25335	COG4644	lycopene metabolic process
HV311_RS25350	COG3385	transposase activity
HV311_RS25365	COG1484	DNA-dependent DNA replication
HV311_RS25370	COG3547	Transposase (IS116 IS110 IS902 family)
HV311_RS25385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV311_RS25390	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HV311_RS25395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV311_RS25415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV311_RS25430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HV311_RS25470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HV311_RS25475	COG1127	ABC transporter
HV311_RS25530	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS25540	COG3344	reverse transcriptase
HV311_RS25560	COG2801	Transposase and inactivated derivatives
HV311_RS25570	COG2801	Transposase and inactivated derivatives
HV311_RS25580	COG2801	Transposase and inactivated derivatives
HV311_RS25590	COG2801	Transposase and inactivated derivatives
HV311_RS25645	COG1802	Transcriptional regulator
HV311_RS25700	COG2974	May be involved in recombination
HV311_RS25850	COG3423	Transcriptional regulator
HV311_RS25865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HV311_RS25870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HV311_RS25895	COG0789	Transcriptional regulator
HV311_RS25905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HV311_RS25910	COG1522	sequence-specific DNA binding
HV311_RS25970	COG2948	multi-organism process
HV311_RS25980	COG0583	DNA-binding transcription factor activity
HV311_RS25985	COG1846	Transcriptional regulator
HV311_RS26005	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HV311_RS26020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HV311_RS26030	COG0583	DNA-binding transcription factor activity
HV311_RS26050	COG0625	glutathione transferase activity
HV311_RS26160	COG0210	DNA helicase
HV311_RS26505	COG1199	ATP-dependent helicase activity
HV311_RS26645	COG5654	RES domain protein
HV311_RS26650	COG5642	Protein of unknown function (DUF2384)
HV311_RS26700	COG1192	Involved in chromosome partitioning
HV311_RS26750	COG4372	Transposase
HV311_RS26755	COG3436	PFAM IS66 Orf2 family protein
HV311_RS26775	COG0305	Participates in initiation and elongation during chromosome replication
HV311_RS26895	COG3692	DNA binding
HV311_RS26905	COG1192	Involved in chromosome partitioning
HV311_RS26955	COG0653	protein targeting
HV311_RS26965	COG4644	lycopene metabolic process
HV311_RS27005	COG0058	SHG alpha-glucan phosphorylase activity
HV311_RS27010	COG0033	Phosphoglucomutase
HV311_RS27020	COG3344	reverse transcriptase
HV311_RS27030	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS27080	COG0625	glutathione transferase activity
HV311_RS27115	COG1192	Involved in chromosome partitioning
HV311_RS27125	COG2894	cell division
HV311_RS27160	COG0484	heat shock protein binding
HV311_RS27305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HV311_RS27345	COG3609	addiction module antidote protein, CC2985 family
HV311_RS27390	COG2801	Transposase and inactivated derivatives
HV311_RS27505	COG4644	lycopene metabolic process
HV311_RS27560	COG2026	Addiction module toxin, RelE StbE family
HV311_RS27565	COG3077	Addiction module antitoxin, RelB DinJ family
HV311_RS27575	COG2826	transposase and inactivated derivatives, IS30 family
HV311_RS27600	COG2801	Transposase and inactivated derivatives
HV311_RS27620	COG2801	Transposase and inactivated derivatives
HV311_RS27775	COG1285	pathogenesis
HV311_RS27785	COG1349	DNA-binding transcription factor activity
HV311_RS27790	COG3395	kinase activity
HV311_RS27795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HV311_RS27800	COG2610	gluconate transmembrane transporter activity