locus-tag	class	description
JMW47_RS00035	COG0288	reversible hydration of carbon dioxide
JMW47_RS00050	COG1132	(ABC) transporter
JMW47_RS00075	COG0628	permease
JMW47_RS00080	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JMW47_RS00085	COG1309	transcriptional regulator
JMW47_RS00100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW47_RS00130	COG1528	Iron-storage protein
JMW47_RS00150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW47_RS00170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW47_RS00175	COG1554	hydrolase, family 65, central catalytic
JMW47_RS00180	COG1705	Flagellar rod assembly protein muramidase FlgJ
JMW47_RS00205	COG0596	Alpha beta hydrolase
JMW47_RS00210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JMW47_RS00215	COG0243	molybdopterin cofactor binding
JMW47_RS00220	COG0437	4 iron, 4 sulfur cluster binding
JMW47_RS00225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMW47_RS00250	COG1126	abc transporter atp-binding protein
JMW47_RS00255	COG1301	dicarboxylic acid transport
JMW47_RS00275	COG1151	hydroxylamine reductase activity
JMW47_RS00285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMW47_RS00285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMW47_RS00300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMW47_RS00340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JMW47_RS00345	COG1160	GTP binding
JMW47_RS00355	COG1363	Peptidase, m42
JMW47_RS00375	COG2720	vancomycin resistance protein
JMW47_RS00390	COG1193	negative regulation of DNA recombination
JMW47_RS00410	COG1686	Belongs to the peptidase S11 family
JMW47_RS00415	COG0052	Belongs to the universal ribosomal protein uS2 family
JMW47_RS00420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JMW47_RS00425	COG0528	UMP kinase activity
JMW47_RS00430	COG0233	cytoplasmic translational termination
JMW47_RS00445	COG4589	Belongs to the CDS family
JMW47_RS00505	COG1518	maintenance of DNA repeat elements
JMW47_RS00510	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JMW47_RS00520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JMW47_RS00525	COG0750	zinc metalloprotease
JMW47_RS00530	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JMW47_RS00550	COG1247	-acetyltransferase
JMW47_RS00595	COG0492	ferredoxin-NADP+ reductase activity
JMW47_RS00600	COG1217	gtp-binding protein TYPA
JMW47_RS00615	COG2217	Heavy metal translocating P-type atpase
JMW47_RS00620	COG0745	RESPONSE REGULATOR receiver
JMW47_RS00625	COG5002	protein histidine kinase activity
JMW47_RS00635	COG1349	DNA-binding transcription factor activity
JMW47_RS00640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMW47_RS00650	COG0534	Mate efflux family protein
JMW47_RS00655	COG2252	PERMEase
JMW47_RS00665	COG1131	(ABC) transporter
JMW47_RS00700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW47_RS00700	COG2080	2 iron, 2 sulfur cluster binding
JMW47_RS00710	COG4708	membrane
JMW47_RS00725	COG1401	restriction endodeoxyribonuclease activity
JMW47_RS00735	COG3829	transcription factor binding
JMW47_RS00760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW47_RS00785	COG0402	S-adenosylhomocysteine deaminase activity
JMW47_RS00805	COG0402	S-adenosylhomocysteine deaminase activity
JMW47_RS00810	COG0167	dihydroorotate dehydrogenase activity
JMW47_RS00820	COG2233	PERMEase
JMW47_RS00830	COG2080	2 iron, 2 sulfur cluster binding
JMW47_RS00830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW47_RS00840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMW47_RS00855	COG0488	(ABC) transporter
JMW47_RS00865	COG0582	viral genome integration into host DNA
JMW47_RS00895	COG1597	lipid kinase activity
JMW47_RS00900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMW47_RS00925	COG0527	aspartate kinase activity
JMW47_RS00930	COG0019	diaminopimelate decarboxylase activity
JMW47_RS00940	COG0628	permease
JMW47_RS00945	COG1187	pseudouridine synthase activity
JMW47_RS00950	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JMW47_RS00955	COG1737	Transcriptional regulator
JMW47_RS00975	COG3655	Transcriptional regulator
JMW47_RS01000	COG1309	transcriptional regulator
JMW47_RS01010	COG0456	acetyltransferase
JMW47_RS01020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JMW47_RS01025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JMW47_RS01030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JMW47_RS01035	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JMW47_RS01045	COG1794	racemase activity, acting on amino acids and derivatives
JMW47_RS01070	COG1725	Transcriptional regulator
JMW47_RS01090	COG2814	Major facilitator Superfamily
JMW47_RS01095	COG2207	Transcriptional regulator
JMW47_RS01125	COG0129	dihydroxy-acid dehydratase activity
JMW47_RS01140	COG1404	Belongs to the peptidase S8 family
JMW47_RS01155	COG0789	Transcriptional regulator
JMW47_RS01160	COG1321	iron dependent repressor
JMW47_RS01165	COG2207	Transcriptional regulator
JMW47_RS01170	COG0730	response to heat
JMW47_RS01295	COG2247	cell wall binding repeat
JMW47_RS01295	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS01300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW47_RS01310	COG0494	nUDIX hydrolase
JMW47_RS01315	COG0384	phenazine biosynthesis protein PhzF
JMW47_RS01320	COG1733	regulation of RNA biosynthetic process
JMW47_RS01345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW47_RS01350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JMW47_RS01355	COG1116	anion transmembrane transporter activity
JMW47_RS01360	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMW47_RS01365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JMW47_RS01370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JMW47_RS01375	COG1923	regulation of RNA biosynthetic process
JMW47_RS01380	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JMW47_RS01385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW47_RS01400	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
JMW47_RS01405	COG1811	Na channel or pump
JMW47_RS01435	COG2264	protein methyltransferase activity
JMW47_RS01445	COG0577	efflux transmembrane transporter activity
JMW47_RS01445	COG1136	(ABC) transporter
JMW47_RS01450	COG5002	protein histidine kinase activity
JMW47_RS01455	COG0745	RESPONSE REGULATOR receiver
JMW47_RS01465	COG0745	RESPONSE REGULATOR receiver
JMW47_RS01470	COG2205	protein histidine kinase activity
JMW47_RS01475	COG1136	(ABC) transporter
JMW47_RS01475	COG0577	efflux transmembrane transporter activity
JMW47_RS01495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMW47_RS01500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW47_RS01505	COG2205	protein histidine kinase activity
JMW47_RS01515	COG1136	(ABC) transporter
JMW47_RS01525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JMW47_RS01545	COG0511	ligase activity, forming carbon-carbon bonds
JMW47_RS01550	COG0439	Biotin carboxylase
JMW47_RS01555	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JMW47_RS01560	COG0825	malonyl-CoA metabolic process
JMW47_RS01565	COG2359	stage V sporulation protein S
JMW47_RS01580	COG4974	Belongs to the 'phage' integrase family
JMW47_RS01585	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JMW47_RS01605	COG1116	anion transmembrane transporter activity
JMW47_RS01625	COG4766	ethanolamine catabolic process
JMW47_RS01630	COG3192	ethanolamine utilization protein
JMW47_RS01640	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
JMW47_RS01650	COG4869	propanediol catabolic process
JMW47_RS01665	COG1012	belongs to the aldehyde dehydrogenase family
JMW47_RS01665	COG1454	alcohol dehydrogenase
JMW47_RS01680	COG4302	ethanolamine ammonia-lyase activity
JMW47_RS01685	COG4303	Ethanolamine ammonia lyase large subunit
JMW47_RS01690	COG4819	ethanolamine utilization protein
JMW47_RS01730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW47_RS01800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JMW47_RS01805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMW47_RS01820	COG3328	transposase activity
JMW47_RS01835	COG2315	Protein conserved in bacteria
JMW47_RS01845	COG3843	relaxase mobilization nuclease domain protein
JMW47_RS01855	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JMW47_RS01875	COG3843	relaxase mobilization nuclease domain protein
JMW47_RS01895	COG0551	DNA topoisomerase type I activity
JMW47_RS01895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMW47_RS01995	COG0358	DNA primase activity
JMW47_RS02040	COG0596	Alpha beta hydrolase
JMW47_RS02075	COG4509	Sortase family
JMW47_RS02080	COG0488	(ABC) transporter
JMW47_RS02090	COG2003	Belongs to the UPF0758 family
JMW47_RS02135	COG0791	NLP P60 protein
JMW47_RS02135	COG1388	LysM domain
JMW47_RS02170	COG1484	DNA-dependent DNA replication
JMW47_RS02205	COG1475	DNA binding
JMW47_RS02210	COG1192	Involved in chromosome partitioning
JMW47_RS02220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMW47_RS02260	COG2131	deaminase
JMW47_RS02290	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
JMW47_RS02295	COG2226	methyltransferase
JMW47_RS02300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JMW47_RS02320	COG5001	Diguanylate cyclase
JMW47_RS02320	COG5002	protein histidine kinase activity
JMW47_RS02330	COG0287	Prephenate dehydrogenase
JMW47_RS02340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JMW47_RS02345	COG0077	Prephenate dehydratase
JMW47_RS02345	COG1605	Chorismate mutase
JMW47_RS02350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JMW47_RS02355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JMW47_RS02360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JMW47_RS02365	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JMW47_RS02370	COG0598	Magnesium transport protein CorA
JMW47_RS02380	COG2205	protein histidine kinase activity
JMW47_RS02385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMW47_RS02390	COG1846	Transcriptional regulator
JMW47_RS02395	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JMW47_RS02410	COG3022	response to hydroperoxide
JMW47_RS02415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JMW47_RS02430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JMW47_RS02435	COG0204	Acyl-transferase
JMW47_RS02440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JMW47_RS02445	COG2081	HI0933 family
JMW47_RS02450	COG0406	alpha-ribazole phosphatase activity
JMW47_RS02480	COG2814	Major facilitator Superfamily
JMW47_RS02490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMW47_RS02495	COG1621	beta-fructofuranosidase activity
JMW47_RS02505	COG1609	Transcriptional regulator
JMW47_RS02515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW47_RS02530	COG0583	DNA-binding transcription factor activity
JMW47_RS02535	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMW47_RS02560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JMW47_RS02575	COG2323	membrane
JMW47_RS02585	COG0789	Transcriptional regulator
JMW47_RS02595	COG0137	argininosuccinate synthase activity
JMW47_RS02605	COG5002	protein histidine kinase activity
JMW47_RS02605	COG3850	Histidine kinase
JMW47_RS02620	COG0116	Belongs to the methyltransferase superfamily
JMW47_RS02625	COG1606	tRNA processing
JMW47_RS02635	COG1393	Belongs to the ArsC family
JMW47_RS02645	COG0765	amino acid transport
JMW47_RS02650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMW47_RS02695	COG0494	nUDIX hydrolase
JMW47_RS02705	COG3326	Membrane
JMW47_RS02740	COG0242	peptide deformylase activity
JMW47_RS02765	COG1309	transcriptional regulator
JMW47_RS02780	COG1924	4 iron, 4 sulfur cluster binding
JMW47_RS02785	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
JMW47_RS02815	COG0786	glutamate:sodium symporter activity
JMW47_RS02850	COG2204	response regulator
JMW47_RS02855	COG5002	protein histidine kinase activity
JMW47_RS02860	COG2610	gluconate transmembrane transporter activity
JMW47_RS02865	COG1917	Cupin 2, conserved barrel domain protein
JMW47_RS02865	COG1396	sequence-specific DNA binding
JMW47_RS02870	COG1011	Hydrolase
JMW47_RS02880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JMW47_RS02885	COG5012	cobalamin binding
JMW47_RS02940	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JMW47_RS02945	COG2207	Transcriptional regulator
JMW47_RS02950	COG1283	sodium-dependent phosphate transmembrane transporter activity
JMW47_RS03025	COG0315	cyclic pyranopterin monophosphate synthase activity
JMW47_RS03035	COG0521	Mo-molybdopterin cofactor biosynthetic process
JMW47_RS03040	COG0393	Putative heavy-metal-binding
JMW47_RS03060	COG1288	antiporter activity
JMW47_RS03075	COG2022	thiamine diphosphate biosynthetic process
JMW47_RS03090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JMW47_RS03095	COG0514	ATP-dependent DNA helicase (RecQ)
JMW47_RS03110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMW47_RS03110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMW47_RS03125	COG1115	amino acid carrier protein
JMW47_RS03155	COG3118	belongs to the thioredoxin family
JMW47_RS03160	COG5002	protein histidine kinase activity
JMW47_RS03165	COG0745	RESPONSE REGULATOR receiver
JMW47_RS03200	COG1309	transcriptional regulator
JMW47_RS03225	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JMW47_RS03230	COG1733	regulation of RNA biosynthetic process
JMW47_RS03245	COG2205	protein histidine kinase activity
JMW47_RS03250	COG0745	RESPONSE REGULATOR receiver
JMW47_RS03260	COG1131	(ABC) transporter
JMW47_RS03275	COG0584	glycerophosphoryl diester phosphodiesterase
JMW47_RS03285	COG1396	sequence-specific DNA binding
JMW47_RS03315	COG3123	guanosine phosphorylase activity
JMW47_RS03320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW47_RS03325	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JMW47_RS03330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JMW47_RS03340	COG1757	Na H antiporter
JMW47_RS03345	COG0095	Lipoate-protein ligase
JMW47_RS03360	COG5001	Diguanylate cyclase
JMW47_RS03360	COG4251	negative regulation of phosphorylation
JMW47_RS03360	COG3706	GGDEF domain
JMW47_RS03360	COG2203	Gaf domain
JMW47_RS03365	COG4607	ABC-type enterochelin transport system periplasmic component
JMW47_RS03370	COG4604	ABC transporter, ATP-binding protein
JMW47_RS03375	COG4605	iron ion homeostasis
JMW47_RS03380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW47_RS03390	COG5505	Protein of unknown function (DUF819)
JMW47_RS03420	COG3853	Toxic anion resistance protein (TelA)
JMW47_RS03435	COG2310	stress, protein
JMW47_RS03450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMW47_RS03455	COG0367	asparagine synthase
JMW47_RS03475	COG0426	domain, Protein
JMW47_RS03485	COG0668	transmembrane transport
JMW47_RS03500	COG1131	(ABC) transporter
JMW47_RS03505	COG1725	Transcriptional regulator
JMW47_RS03510	COG5001	Diguanylate cyclase
JMW47_RS03510	COG3300	MHYT domain
JMW47_RS03515	COG1668	transmembrane transport
JMW47_RS03520	COG4555	ABC transporter
JMW47_RS03530	COG0402	S-adenosylhomocysteine deaminase activity
JMW47_RS03555	COG1131	(ABC) transporter
JMW47_RS03560	COG1725	Transcriptional regulator
JMW47_RS03580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS03585	COG0352	thiamine-phosphate diphosphorylase activity
JMW47_RS03590	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JMW47_RS03595	COG0351	phosphomethylpyrimidine kinase
JMW47_RS03610	COG0024	Methionine aminopeptidase
JMW47_RS03620	COG1045	serine acetyltransferase
JMW47_RS03625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JMW47_RS03630	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JMW47_RS03635	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JMW47_RS03640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JMW47_RS03650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW47_RS03670	COG0596	Alpha beta hydrolase
JMW47_RS03675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JMW47_RS03685	COG0460	homoserine dehydrogenase
JMW47_RS03690	COG5002	protein histidine kinase activity
JMW47_RS03695	COG1295	ribonuclease BN
JMW47_RS03700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW47_RS03710	COG1388	LysM domain
JMW47_RS03710	COG3584	3D domain protein
JMW47_RS03730	COG1136	(ABC) transporter
JMW47_RS03735	COG2267	carboxylic ester hydrolase activity
JMW47_RS03745	COG1331	Highly conserved protein containing a thioredoxin domain
JMW47_RS03750	COG3546	catalase activity
JMW47_RS03755	COG0028	Belongs to the TPP enzyme family
JMW47_RS03760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JMW47_RS03775	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JMW47_RS03790	COG1595	DNA-templated transcription, initiation
JMW47_RS03805	COG0531	amino acid
JMW47_RS03810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JMW47_RS03810	COG0140	phosphoribosyl-ATP diphosphatase activity
JMW47_RS03815	COG0107	imidazoleglycerol-phosphate synthase activity
JMW47_RS03820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JMW47_RS03825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JMW47_RS03830	COG0131	Imidazoleglycerol-phosphate dehydratase
JMW47_RS03835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW47_RS03840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JMW47_RS03845	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JMW47_RS03885	COG0577	efflux transmembrane transporter activity
JMW47_RS03890	COG1136	(ABC) transporter
JMW47_RS03900	COG0493	'glutamate synthase
JMW47_RS03900	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW47_RS03915	COG0405	Gamma-glutamyltransferase
JMW47_RS03920	COG0577	efflux transmembrane transporter activity
JMW47_RS03925	COG1136	(ABC) transporter
JMW47_RS03930	COG0745	RESPONSE REGULATOR receiver
JMW47_RS03935	COG2205	protein histidine kinase activity
JMW47_RS03945	COG0577	efflux transmembrane transporter activity
JMW47_RS03945	COG1136	(ABC) transporter
JMW47_RS03950	COG0577	efflux transmembrane transporter activity
JMW47_RS03955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JMW47_RS03960	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW47_RS03965	COG1592	Rubrerythrin
JMW47_RS03965	COG1773	rubredoxin
JMW47_RS03975	COG0726	polysaccharide deacetylase
JMW47_RS03980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JMW47_RS04000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JMW47_RS04005	COG4978	Transcriptional regulator
JMW47_RS04005	COG0789	Transcriptional regulator
JMW47_RS04010	COG5001	Diguanylate cyclase
JMW47_RS04020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JMW47_RS04025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JMW47_RS04050	COG0348	domain, Protein
JMW47_RS04050	COG3901	Regulator of nitric oxide reductase transcription
JMW47_RS04065	COG0534	Mate efflux family protein
JMW47_RS04075	COG1131	(ABC) transporter
JMW47_RS04085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JMW47_RS04100	COG0701	Predicted permease
JMW47_RS04105	COG0523	cobalamin synthesis protein
JMW47_RS04110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMW47_RS04115	COG1121	(ABC) transporter
JMW47_RS04120	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMW47_RS04140	COG4086	secreted protein
JMW47_RS04145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMW47_RS04150	COG1396	sequence-specific DNA binding
JMW47_RS04155	COG2094	Belongs to the DNA glycosylase MPG family
JMW47_RS04160	COG5002	protein histidine kinase activity
JMW47_RS04165	COG1464	Belongs to the NlpA lipoprotein family
JMW47_RS04170	COG2011	ABC-type metal ion transport system permease component
JMW47_RS04175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JMW47_RS04210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW47_RS04245	COG0412	Dienelactone hydrolase
JMW47_RS04250	COG1773	rubredoxin
JMW47_RS04250	COG1592	Rubrerythrin
JMW47_RS04255	COG1132	(ABC) transporter
JMW47_RS04260	COG1132	(ABC) transporter
JMW47_RS04290	COG1136	(ABC) transporter
JMW47_RS04290	COG0577	efflux transmembrane transporter activity
JMW47_RS04295	COG5002	protein histidine kinase activity
JMW47_RS04295	COG3850	Histidine kinase
JMW47_RS04300	COG0745	RESPONSE REGULATOR receiver
JMW47_RS04310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS04330	COG0655	NAD(P)H dehydrogenase (quinone) activity
JMW47_RS04335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JMW47_RS04340	COG2384	SAM-dependent methyltransferase
JMW47_RS04345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JMW47_RS04350	COG0358	DNA primase activity
JMW47_RS04355	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JMW47_RS04360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JMW47_RS04365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JMW47_RS04370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JMW47_RS04375	COG0302	gtp cyclohydrolase
JMW47_RS04385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JMW47_RS04390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JMW47_RS04395	COG0512	Glutamine amidotransferase of anthranilate synthase
JMW47_RS04400	COG0726	polysaccharide deacetylase
JMW47_RS04405	COG2340	Cysteine-rich secretory protein family
JMW47_RS04415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW47_RS04420	COG1346	cytolysis
JMW47_RS04435	COG3829	transcription factor binding
JMW47_RS04440	COG2720	vancomycin resistance protein
JMW47_RS04455	COG0450	alkyl hydroperoxide reductase
JMW47_RS04470	COG0726	polysaccharide deacetylase
JMW47_RS04480	COG1285	pathogenesis
JMW47_RS04490	COG0789	Transcriptional regulator
JMW47_RS04490	COG4978	Transcriptional regulator
JMW47_RS04500	COG2199	diguanylate cyclase activity
JMW47_RS04500	COG2203	Gaf domain
JMW47_RS04505	COG5002	protein histidine kinase activity
JMW47_RS04505	COG3447	MASE1 domain protein
JMW47_RS04505	COG5001	Diguanylate cyclase
JMW47_RS04510	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JMW47_RS04535	COG1242	4 iron, 4 sulfur cluster binding
JMW47_RS04545	COG3829	transcription factor binding
JMW47_RS04560	COG1546	Belongs to the CinA family
JMW47_RS04560	COG1058	Belongs to the CinA family
JMW47_RS04565	COG1181	Belongs to the D-alanine--D-alanine ligase family
JMW47_RS04570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS04610	COG0584	glycerophosphoryl diester phosphodiesterase
JMW47_RS04625	COG1619	proteins homologs of microcin C7 resistance protein MccF
JMW47_RS04630	COG1473	amidohydrolase
JMW47_RS04675	COG4948	Mandelate Racemase Muconate Lactonizing
JMW47_RS04680	COG1396	sequence-specific DNA binding
JMW47_RS04685	COG1984	allophanate hydrolase subunit 2
JMW47_RS04690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JMW47_RS04695	COG1914	H( )-stimulated, divalent metal cation uptake system
JMW47_RS04700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JMW47_RS04705	COG0471	metal ion transport
JMW47_RS04705	COG3273	potassium ion transport
JMW47_RS04710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JMW47_RS04720	COG2814	Major facilitator Superfamily
JMW47_RS04725	COG1396	sequence-specific DNA binding
JMW47_RS04740	COG1396	sequence-specific DNA binding
JMW47_RS04770	COG3778	Protein conserved in bacteria
JMW47_RS04775	COG3299	homolog of phage Mu protein gp47
JMW47_RS04845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMW47_RS04855	COG1278	Cold shock
JMW47_RS04885	COG1131	(ABC) transporter
JMW47_RS04910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW47_RS04925	COG0708	Exodeoxyribonuclease III
JMW47_RS04935	COG0436	Aminotransferase
JMW47_RS04945	COG0114	fumarate hydratase activity
JMW47_RS04955	COG1968	undecaprenyl-diphosphatase activity
JMW47_RS04980	COG5001	Diguanylate cyclase
JMW47_RS04985	COG1418	mRNA catabolic process
JMW47_RS04990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JMW47_RS05000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW47_RS05005	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JMW47_RS05015	COG0740	serine-type endopeptidase activity
JMW47_RS05020	COG0527	aspartate kinase activity
JMW47_RS05025	COG1873	PFAM PRC-barrel domain
JMW47_RS05030	COG0612	Peptidase, M16
JMW47_RS05035	COG0726	polysaccharide deacetylase
JMW47_RS05040	COG1185	polyribonucleotide nucleotidyltransferase activity
JMW47_RS05045	COG1307	EDD domain protein, DegV family
JMW47_RS05050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JMW47_RS05055	COG0196	riboflavin kinase activity
JMW47_RS05060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JMW47_RS05065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JMW47_RS05075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JMW47_RS05085	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JMW47_RS05090	COG0195	Participates in both transcription termination and antitermination
JMW47_RS05095	COG0779	Required for maturation of 30S ribosomal subunits
JMW47_RS05150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JMW47_RS05160	COG1994	Peptidase M50
JMW47_RS05165	COG1917	Cupin 2, conserved barrel domain protein
JMW47_RS05165	COG2207	Transcriptional regulator
JMW47_RS05175	COG1686	Belongs to the peptidase S11 family
JMW47_RS05185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMW47_RS05195	COG0735	belongs to the Fur family
JMW47_RS05200	COG3906	Belongs to the UPF0473 family
JMW47_RS05205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JMW47_RS05215	COG4472	Bacterial protein of unknown function (DUF965)
JMW47_RS05220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMW47_RS05225	COG0482	sulfurtransferase activity
JMW47_RS05230	COG0822	iron-sulfur transferase activity
JMW47_RS05240	COG1959	2 iron, 2 sulfur cluster binding
JMW47_RS05250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JMW47_RS05260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMW47_RS05265	COG0758	DNA mediated transformation
JMW47_RS05270	COG0606	chelatase, subunit chli
JMW47_RS05275	COG0792	nuclease activity
JMW47_RS05280	COG4585	Histidine kinase
JMW47_RS05285	COG2197	response regulator
JMW47_RS05290	COG1131	(ABC) transporter
JMW47_RS05320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMW47_RS05335	COG1114	Component of the transport system for branched-chain amino acids
JMW47_RS05345	COG0335	large ribosomal subunit rRNA binding
JMW47_RS05350	COG0336	Belongs to the RNA methyltransferase TrmD family
JMW47_RS05355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JMW47_RS05365	COG0228	four-way junction DNA binding
JMW47_RS05370	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JMW47_RS05380	COG0552	protein localization to endoplasmic reticulum
JMW47_RS05385	COG1196	nuclear chromosome segregation
JMW47_RS05395	COG0571	ribonuclease III activity
JMW47_RS05405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JMW47_RS05500	COG0768	penicillin binding
JMW47_RS05505	COG0826	peptidase U32
JMW47_RS05510	COG4122	O-methyltransferase activity
JMW47_RS05515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JMW47_RS05530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JMW47_RS05535	COG4974	Belongs to the 'phage' integrase family
JMW47_RS05545	COG0494	nUDIX hydrolase
JMW47_RS05580	COG0750	zinc metalloprotease
JMW47_RS05585	COG0456	acetyltransferase
JMW47_RS05590	COG0456	acetyltransferase
JMW47_RS05600	COG0497	DNA recombination
JMW47_RS05605	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JMW47_RS05610	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JMW47_RS05615	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JMW47_RS05625	COG1722	exodeoxyribonuclease VII activity
JMW47_RS05630	COG1570	exodeoxyribonuclease VII activity
JMW47_RS05635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMW47_RS05640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMW47_RS05645	COG1302	Protein conserved in bacteria
JMW47_RS05685	COG3854	ATPases associated with a variety of cellular activities
JMW47_RS05690	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JMW47_RS05705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JMW47_RS05720	COG3706	GGDEF domain
JMW47_RS05725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JMW47_RS05730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMW47_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
JMW47_RS05740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JMW47_RS05750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMW47_RS05755	COG0416	fatty acid biosynthetic process
JMW47_RS05765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JMW47_RS05775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JMW47_RS05780	COG1323	Belongs to the UPF0348 family
JMW47_RS05785	COG0277	FAD linked oxidase domain protein
JMW47_RS05790	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW47_RS05795	COG2086	electron transfer activity
JMW47_RS05800	COG3875	lactate racemase activity
JMW47_RS05805	COG2186	Transcriptional regulator
JMW47_RS05810	COG3314	Sporulation integral membrane protein YlbJ
JMW47_RS05820	COG0460	homoserine dehydrogenase
JMW47_RS05830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JMW47_RS05835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JMW47_RS05845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JMW47_RS05850	COG1530	ribonuclease E activity
JMW47_RS05865	COG0426	domain, Protein
JMW47_RS05880	COG1695	Transcriptional regulator
JMW47_RS05885	COG1803	Methylglyoxal synthase
JMW47_RS05890	COG0772	Belongs to the SEDS family
JMW47_RS05895	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JMW47_RS05900	COG2894	cell division
JMW47_RS05905	COG0850	regulation of cytokinetic process
JMW47_RS05925	COG1077	Cell shape determining protein MreB Mrl
JMW47_RS05930	COG2003	Belongs to the UPF0758 family
JMW47_RS05935	COG0424	maF-like protein
JMW47_RS05940	COG1245	4Fe-4S binding domain
JMW47_RS05940	COG2878	Part of a membrane complex involved in electron transport
JMW47_RS05945	COG4657	Part of a membrane complex involved in electron transport
JMW47_RS05950	COG4660	Part of a membrane complex involved in electron transport
JMW47_RS05955	COG4659	FMN binding
JMW47_RS05960	COG4658	electron transport chain
JMW47_RS05965	COG4656	Part of a membrane complex involved in electron transport
JMW47_RS05975	COG0791	NLP P60 protein
JMW47_RS05980	COG0346	lactoylglutathione lyase activity
JMW47_RS06005	COG0237	dephospho-CoA kinase activity
JMW47_RS06010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMW47_RS06010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMW47_RS06045	COG3708	Transcriptional regulator
JMW47_RS06045	COG2207	Transcriptional regulator
JMW47_RS06070	COG1396	sequence-specific DNA binding
JMW47_RS06075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMW47_RS06080	COG1882	Formate acetyltransferase
JMW47_RS06095	COG3279	Response regulator of the LytR AlgR family
JMW47_RS06110	COG1473	amidohydrolase
JMW47_RS06120	COG1132	(ABC) transporter
JMW47_RS06125	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW47_RS06145	COG0583	DNA-binding transcription factor activity
JMW47_RS06150	COG3716	PTS system mannose fructose sorbose family IID component
JMW47_RS06155	COG3715	PTS system
JMW47_RS06175	COG2188	Transcriptional regulator
JMW47_RS06180	COG1362	aminopeptidase activity
JMW47_RS06185	COG4224	UPF0291 protein
JMW47_RS06190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS06195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW47_RS06250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMW47_RS06260	COG0564	pseudouridine synthase activity
JMW47_RS06265	COG0183	Belongs to the thiolase family
JMW47_RS06280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW47_RS06285	COG2086	electron transfer activity
JMW47_RS06290	COG1960	acyl-CoA dehydrogenase activity
JMW47_RS06295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMW47_RS06310	COG1131	(ABC) transporter
JMW47_RS06315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JMW47_RS06320	COG0622	Phosphoesterase
JMW47_RS06330	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW47_RS06340	COG4536	flavin adenine dinucleotide binding
JMW47_RS06345	COG0419	ATPase involved in DNA repair
JMW47_RS06350	COG0420	3'-5' exonuclease activity
JMW47_RS06355	COG1074	ATP-dependent DNA helicase activity
JMW47_RS06360	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JMW47_RS06370	COG1074	ATP-dependent DNA helicase activity
JMW47_RS06380	COG2247	cell wall binding repeat
JMW47_RS06380	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS06385	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS06415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JMW47_RS06430	COG1215	transferase activity, transferring glycosyl groups
JMW47_RS06435	COG5298	Protein conserved in bacteria
JMW47_RS06445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JMW47_RS06450	COG1177	transmembrane transport
JMW47_RS06455	COG1176	ABC-type spermidine putrescine transport system, permease component I
JMW47_RS06460	COG3842	ATPase activity
JMW47_RS06470	COG2364	Membrane
JMW47_RS06490	COG1132	(ABC) transporter
JMW47_RS06500	COG4978	Transcriptional regulator
JMW47_RS06500	COG0789	Transcriptional regulator
JMW47_RS06510	COG5001	Diguanylate cyclase
JMW47_RS06515	COG5002	protein histidine kinase activity
JMW47_RS06530	COG0363	glucosamine-6-phosphate deaminase activity
JMW47_RS06535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JMW47_RS06555	COG0577	efflux transmembrane transporter activity
JMW47_RS06555	COG1136	(ABC) transporter
JMW47_RS06560	COG5002	protein histidine kinase activity
JMW47_RS06565	COG0745	RESPONSE REGULATOR receiver
JMW47_RS06580	COG0281	malic enzyme
JMW47_RS06590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JMW47_RS06595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMW47_RS06620	COG5001	Diguanylate cyclase
JMW47_RS06620	COG3447	MASE1 domain protein
JMW47_RS06620	COG5002	protein histidine kinase activity
JMW47_RS06630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMW47_RS06645	COG0473	3-isopropylmalate dehydrogenase activity
JMW47_RS06650	COG0066	3-isopropylmalate dehydratase activity
JMW47_RS06655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JMW47_RS06660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JMW47_RS06670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW47_RS06675	COG0539	negative regulation of cytoplasmic translation
JMW47_RS06675	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JMW47_RS06680	COG0534	Mate efflux family protein
JMW47_RS06710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMW47_RS06715	COG1174	glycine betaine transport
JMW47_RS06725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMW47_RS06730	COG4868	Belongs to the UPF0371 family
JMW47_RS06765	COG0010	Belongs to the arginase family
JMW47_RS06770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JMW47_RS06775	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JMW47_RS06780	COG1982	Orn Lys Arg decarboxylase major
JMW47_RS06785	COG1802	Transcriptional regulator
JMW47_RS06795	COG0058	SHG alpha-glucan phosphorylase activity
JMW47_RS06800	COG0297	glycogen (starch) synthase activity
JMW47_RS06805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JMW47_RS06810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JMW47_RS06825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JMW47_RS06825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JMW47_RS06830	COG4120	Belongs to the binding-protein-dependent transport system permease family
JMW47_RS06840	COG2984	ABC transporter substrate binding protein
JMW47_RS06845	COG4120	Belongs to the binding-protein-dependent transport system permease family
JMW47_RS06860	COG0110	maltose O-acetyltransferase activity
JMW47_RS06865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JMW47_RS06870	COG4149	molybdate abc transporter
JMW47_RS06875	COG0725	ABC transporter, periplasmic molybdate-binding protein
JMW47_RS06880	COG1910	domain protein
JMW47_RS06890	COG1073	alpha beta
JMW47_RS06900	COG1486	melibiose metabolic process
JMW47_RS06910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS06925	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS06925	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS06930	COG4608	Belongs to the ABC transporter superfamily
JMW47_RS06935	COG0444	Belongs to the ABC transporter superfamily
JMW47_RS06945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMW47_RS06950	COG0601	transmembrane transport
JMW47_RS06965	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JMW47_RS07005	COG0438	transferase activity, transferring glycosyl groups
JMW47_RS07005	COG0297	glycogen (starch) synthase activity
JMW47_RS07015	COG0138	bifunctional purine biosynthesis protein purh
JMW47_RS07020	COG0179	Fumarylacetoacetate (FAA) hydrolase
JMW47_RS07045	COG1846	Transcriptional regulator
JMW47_RS07050	COG0473	3-isopropylmalate dehydrogenase activity
JMW47_RS07060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JMW47_RS07100	COG0069	glutamate synthase activity
JMW47_RS07105	COG2033	superoxide reductase activity
JMW47_RS07115	COG1592	Rubrerythrin
JMW47_RS07135	COG5002	protein histidine kinase activity
JMW47_RS07140	COG0745	RESPONSE REGULATOR receiver
JMW47_RS07150	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS07155	COG2190	(PTS) system
JMW47_RS07155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS07155	COG1263	PTS System
JMW47_RS07160	COG2814	Major facilitator Superfamily
JMW47_RS07165	COG2186	Transcriptional regulator
JMW47_RS07205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW47_RS07210	COG2086	electron transfer activity
JMW47_RS07225	COG2610	gluconate transmembrane transporter activity
JMW47_RS07230	COG1024	Enoyl-CoA hydratase
JMW47_RS07235	COG0217	transcriptional regulatory protein
JMW47_RS07240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JMW47_RS07245	COG0730	response to heat
JMW47_RS07255	COG1739	Uncharacterized protein family UPF0029
JMW47_RS07270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMW47_RS07285	COG0488	(ABC) transporter
JMW47_RS07290	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS07295	COG0750	zinc metalloprotease
JMW47_RS07305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMW47_RS07315	COG1473	amidohydrolase
JMW47_RS07340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMW47_RS07350	COG1191	sigma factor activity
JMW47_RS07355	COG2172	sigma factor antagonist activity
JMW47_RS07360	COG1366	Belongs to the anti-sigma-factor antagonist family
JMW47_RS07365	COG0243	molybdopterin cofactor binding
JMW47_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
JMW47_RS07400	COG0513	Belongs to the DEAD box helicase family
JMW47_RS07405	COG0530	calcium, potassium:sodium antiporter activity
JMW47_RS07415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMW47_RS07420	COG0778	Nitroreductase
JMW47_RS07430	COG0301	tRNA thio-modification
JMW47_RS07440	COG1126	abc transporter atp-binding protein
JMW47_RS07445	COG0765	amino acid transport
JMW47_RS07450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMW47_RS07455	COG0210	DNA helicase
JMW47_RS07475	COG1360	Flagellar Motor Protein
JMW47_RS07480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JMW47_RS07490	COG1349	DNA-binding transcription factor activity
JMW47_RS07495	COG3192	ethanolamine utilization protein
JMW47_RS07505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW47_RS07505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JMW47_RS07520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW47_RS07540	COG0095	Lipoate-protein ligase
JMW47_RS07560	COG0509	glycine decarboxylation via glycine cleavage system
JMW47_RS07590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMW47_RS07595	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JMW47_RS07595	COG0646	methionine synthase
JMW47_RS07605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JMW47_RS07610	COG3404	Formiminotransferase-cyclodeaminase
JMW47_RS07615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JMW47_RS07625	COG1151	hydroxylamine reductase activity
JMW47_RS07630	COG0280	phosphate acetyltransferase
JMW47_RS07635	COG0110	maltose O-acetyltransferase activity
JMW47_RS07640	COG0583	DNA-binding transcription factor activity
JMW47_RS07665	COG0018	arginyl-trna synthetase
JMW47_RS07670	COG1683	Conserved Protein
JMW47_RS07675	COG1193	negative regulation of DNA recombination
JMW47_RS07680	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW47_RS07685	COG3706	GGDEF domain
JMW47_RS07695	COG1051	belongs to the nudix hydrolase family
JMW47_RS07705	COG0826	peptidase U32
JMW47_RS07725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW47_RS07725	COG0072	phenylalanine-tRNA ligase activity
JMW47_RS07730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JMW47_RS07735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMW47_RS07740	COG0569	domain protein
JMW47_RS07745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JMW47_RS07765	COG0789	Transcriptional regulator
JMW47_RS07810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JMW47_RS07815	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JMW47_RS07820	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JMW47_RS07830	COG1595	DNA-templated transcription, initiation
JMW47_RS07865	COG2205	protein histidine kinase activity
JMW47_RS07865	COG0745	RESPONSE REGULATOR receiver
JMW47_RS07865	COG3292	Two component regulator propeller
JMW47_RS07870	COG0745	RESPONSE REGULATOR receiver
JMW47_RS07955	COG0038	chloride channel
JMW47_RS07975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS07985	COG0823	Involved in the tonB-independent uptake of proteins
JMW47_RS07985	COG4946	Tricorn protease homolog
JMW47_RS07985	COG1506	peptidase
JMW47_RS07990	COG1506	peptidase
JMW47_RS07990	COG4946	Tricorn protease homolog
JMW47_RS07990	COG0823	Involved in the tonB-independent uptake of proteins
JMW47_RS07995	COG1802	Transcriptional regulator
JMW47_RS08000	COG1131	(ABC) transporter
JMW47_RS08055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JMW47_RS08075	COG0305	Participates in initiation and elongation during chromosome replication
JMW47_RS08115	COG0789	Transcriptional regulator
JMW47_RS08115	COG4978	Transcriptional regulator
JMW47_RS08150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JMW47_RS08150	COG0456	acetyltransferase
JMW47_RS08165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JMW47_RS08175	COG3546	catalase activity
JMW47_RS08190	COG1475	DNA binding
JMW47_RS08195	COG3969	phosphoadenosine phosphosulfate
JMW47_RS08240	COG2199	diguanylate cyclase activity
JMW47_RS08245	COG5001	Diguanylate cyclase
JMW47_RS08245	COG1716	ATPase activity
JMW47_RS08250	COG0574	Belongs to the PEP-utilizing enzyme family
JMW47_RS08250	COG3848	Pyruvate phosphate dikinase
JMW47_RS08255	COG1309	transcriptional regulator
JMW47_RS08300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMW47_RS08305	COG4399	Belongs to the UPF0754 family
JMW47_RS08305	COG4399	Belongs to the UPF0754 family
JMW47_RS08335	COG1744	ABC transporter substrate-binding protein PnrA-like
JMW47_RS08345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JMW47_RS08350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JMW47_RS08355	COG1067	ATP-dependent peptidase activity
JMW47_RS08360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMW47_RS08375	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JMW47_RS08385	COG2066	Belongs to the glutaminase family
JMW47_RS08390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMW47_RS08405	COG0681	Belongs to the peptidase S26 family
JMW47_RS08410	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JMW47_RS08410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMW47_RS08415	COG2339	peptidase activity
JMW47_RS08465	COG2201	protein-glutamate methylesterase activity
JMW47_RS08475	COG0835	chemotaxis
JMW47_RS08480	COG0643	Histidine kinase
JMW47_RS08480	COG2198	Histidine kinase
JMW47_RS08485	COG0840	transmembrane signaling receptor activity
JMW47_RS08495	COG0835	chemotaxis
JMW47_RS08500	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JMW47_RS08505	COG1776	CheC inhibitor of MCP methylation
JMW47_RS08510	COG2201	protein-glutamate methylesterase activity
JMW47_RS08520	COG2378	regulation of single-species biofilm formation
JMW47_RS08540	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JMW47_RS08545	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW47_RS08570	COG2205	protein histidine kinase activity
JMW47_RS08590	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS08590	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS08595	COG1686	Belongs to the peptidase S11 family
JMW47_RS08605	COG5002	protein histidine kinase activity
JMW47_RS08615	COG3716	PTS system mannose fructose sorbose family IID component
JMW47_RS08625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS08635	COG1063	alcohol dehydrogenase
JMW47_RS08650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JMW47_RS08655	COG0745	RESPONSE REGULATOR receiver
JMW47_RS08660	COG5002	protein histidine kinase activity
JMW47_RS08665	COG1136	(ABC) transporter
JMW47_RS08670	COG1136	(ABC) transporter
JMW47_RS08670	COG0577	efflux transmembrane transporter activity
JMW47_RS08675	COG5002	protein histidine kinase activity
JMW47_RS08680	COG0745	RESPONSE REGULATOR receiver
JMW47_RS08695	COG1131	(ABC) transporter
JMW47_RS08720	COG0768	penicillin binding
JMW47_RS08800	COG1595	DNA-templated transcription, initiation
JMW47_RS08870	COG1131	(ABC) transporter
JMW47_RS08890	COG0745	RESPONSE REGULATOR receiver
JMW47_RS08895	COG5002	protein histidine kinase activity
JMW47_RS08905	COG1136	(ABC) transporter
JMW47_RS08915	COG3973	AAA domain
JMW47_RS08925	COG1051	belongs to the nudix hydrolase family
JMW47_RS08940	COG1757	Na H antiporter
JMW47_RS08945	COG3457	Alanine racemase
JMW47_RS08955	COG5012	cobalamin binding
JMW47_RS08965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JMW47_RS08975	COG3804	dihydrodipicolinate reductase
JMW47_RS08980	COG3829	transcription factor binding
JMW47_RS08990	COG0626	cystathionine gamma-synthase activity
JMW47_RS09010	COG3254	rhamnose metabolic process
JMW47_RS09025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW47_RS09035	COG0745	RESPONSE REGULATOR receiver
JMW47_RS09040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW47_RS09095	COG1187	pseudouridine synthase activity
JMW47_RS09105	COG0191	fructose-bisphosphate aldolase activity
JMW47_RS09110	COG3829	transcription factor binding
JMW47_RS09115	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW47_RS09120	COG2086	electron transfer activity
JMW47_RS09125	COG1960	acyl-CoA dehydrogenase activity
JMW47_RS09150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMW47_RS09165	COG0367	asparagine synthase
JMW47_RS09170	COG3711	transcriptional antiterminator
JMW47_RS09175	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS09180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS09180	COG1263	PTS System
JMW47_RS09180	COG2190	(PTS) system
JMW47_RS09205	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JMW47_RS09225	COG2357	RelA SpoT domain protein
JMW47_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMW47_RS09260	COG1136	(ABC) transporter
JMW47_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
JMW47_RS09270	COG1454	alcohol dehydrogenase
JMW47_RS09285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JMW47_RS09295	COG1362	aminopeptidase activity
JMW47_RS09300	COG0210	DNA helicase
JMW47_RS09305	COG1122	ATPase activity
JMW47_RS09315	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
JMW47_RS09335	COG0586	Pfam SNARE associated Golgi protein
JMW47_RS09355	COG2217	Heavy metal translocating P-type atpase
JMW47_RS09395	COG1473	amidohydrolase
JMW47_RS09405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW47_RS09410	COG1172	Belongs to the binding-protein-dependent transport system permease family
JMW47_RS09415	COG1129	ABC transporter
JMW47_RS09420	COG1879	ABC-type sugar transport system periplasmic component
JMW47_RS09425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMW47_RS09435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JMW47_RS09455	COG1131	(ABC) transporter
JMW47_RS09475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW47_RS09485	COG3716	PTS system mannose fructose sorbose family IID component
JMW47_RS09510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS09510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS09515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS09515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS09520	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW47_RS09535	COG1733	regulation of RNA biosynthetic process
JMW47_RS09550	COG1533	DNA photolyase activity
JMW47_RS09555	COG1454	alcohol dehydrogenase
JMW47_RS09600	COG1215	transferase activity, transferring glycosyl groups
JMW47_RS09610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JMW47_RS09620	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JMW47_RS09635	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JMW47_RS09640	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JMW47_RS09675	COG0741	lytic transglycosylase activity
JMW47_RS09680	COG1088	dTDP-glucose 4,6-dehydratase activity
JMW47_RS09690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JMW47_RS09705	COG0138	bifunctional purine biosynthesis protein purh
JMW47_RS09710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JMW47_RS09715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JMW47_RS09720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JMW47_RS09725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JMW47_RS09730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JMW47_RS09735	COG0778	Nitroreductase
JMW47_RS09750	COG1011	Hydrolase
JMW47_RS09760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS09765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS09780	COG2771	luxR family
JMW47_RS09780	COG2200	EAL domain
JMW47_RS09785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMW47_RS09840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JMW47_RS09840	COG0519	Catalyzes the synthesis of GMP from XMP
JMW47_RS09845	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JMW47_RS09850	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JMW47_RS09855	COG1691	(AIR) carboxylase
JMW47_RS09860	COG0459	protein refolding
JMW47_RS09865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JMW47_RS09870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMW47_RS09885	COG0583	DNA-binding transcription factor activity
JMW47_RS09895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JMW47_RS09900	COG0167	dihydroorotate dehydrogenase activity
JMW47_RS09905	COG0543	2 iron, 2 sulfur cluster binding
JMW47_RS09910	COG0540	Belongs to the ATCase OTCase family
JMW47_RS09950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JMW47_RS09965	COG1151	hydroxylamine reductase activity
JMW47_RS09975	COG2221	Nitrite and sulphite reductase 4Fe-4S
JMW47_RS09985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JMW47_RS09990	COG0488	(ABC) transporter
JMW47_RS09995	COG0534	Mate efflux family protein
JMW47_RS10025	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMW47_RS10035	COG1882	Formate acetyltransferase
JMW47_RS10040	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMW47_RS10045	COG0456	acetyltransferase
JMW47_RS10050	COG1214	PFAM Peptidase M22, glycoprotease
JMW47_RS10055	COG0802	atpase or kinase
JMW47_RS10070	COG1228	amidohydrolase
JMW47_RS10075	COG2183	response to ionizing radiation
JMW47_RS10085	COG0653	protein targeting
JMW47_RS10090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMW47_RS10100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW47_RS10105	COG1446	asparaginase
JMW47_RS10115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS10120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS10125	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW47_RS10130	COG3711	transcriptional antiterminator
JMW47_RS10130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS10135	COG1040	competence protein
JMW47_RS10140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JMW47_RS10145	COG3949	Membrane
JMW47_RS10150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JMW47_RS10160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JMW47_RS10165	COG1077	Cell shape determining protein MreB Mrl
JMW47_RS10170	COG1609	Transcriptional regulator
JMW47_RS10180	COG2385	sporulation resulting in formation of a cellular spore
JMW47_RS10185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMW47_RS10195	COG2897	thiosulfate sulfurtransferase activity
JMW47_RS10200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JMW47_RS10205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW47_RS10240	COG0280	phosphate acetyltransferase
JMW47_RS10250	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JMW47_RS10495	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS10500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JMW47_RS10505	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JMW47_RS10510	COG0101	tRNA pseudouridine synthase activity
JMW47_RS10515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JMW47_RS10520	COG1122	ATPase activity
JMW47_RS10525	COG1122	ATPase activity
JMW47_RS10530	COG0203	ribosomal protein L17
JMW47_RS10535	COG0202	RNA polymerase activity
JMW47_RS10540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JMW47_RS10545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JMW47_RS10550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JMW47_RS10555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JMW47_RS10560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JMW47_RS10570	COG0024	Methionine aminopeptidase
JMW47_RS10575	COG0563	adenylate kinase activity
JMW47_RS10585	COG0200	Binds to the 23S rRNA
JMW47_RS10590	COG1841	ribosomal large subunit assembly
JMW47_RS10595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JMW47_RS10600	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JMW47_RS10605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JMW47_RS10610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JMW47_RS10615	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMW47_RS10620	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JMW47_RS10625	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JMW47_RS10630	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JMW47_RS10635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JMW47_RS10640	COG0255	Belongs to the universal ribosomal protein uL29 family
JMW47_RS10645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JMW47_RS10650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JMW47_RS10655	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JMW47_RS10660	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JMW47_RS10665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JMW47_RS10670	COG0089	rRNA binding
JMW47_RS10675	COG0088	Forms part of the polypeptide exit tunnel
JMW47_RS10680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JMW47_RS10685	COG0051	transcription antitermination factor activity, RNA binding
JMW47_RS10690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMW47_RS10695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMW47_RS10700	COG0049	tRNA binding
JMW47_RS10705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JMW47_RS10710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMW47_RS10715	COG0085	RNA polymerase activity
JMW47_RS10725	COG0222	ribosome binding
JMW47_RS10730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JMW47_RS10735	COG0081	regulation of translation
JMW47_RS10740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JMW47_RS10745	COG0250	Participates in transcription elongation, termination and antitermination
JMW47_RS10755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JMW47_RS10760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMW47_RS10770	COG3688	RNA-binding protein containing a PIN domain
JMW47_RS10775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMW47_RS10790	COG0215	cysteine-tRNA ligase activity
JMW47_RS10800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMW47_RS10805	COG0442	prolyl-tRNA aminoacylation
JMW47_RS10810	COG0442	prolyl-tRNA aminoacylation
JMW47_RS10815	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JMW47_RS10820	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JMW47_RS10825	COG0095	Lipoate-protein ligase
JMW47_RS10840	COG3775	system Galactitol-specific IIC component
JMW47_RS10845	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW47_RS10855	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS10855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS10860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMW47_RS10865	COG0508	dehydrogenase complex catalyzes the overall conversion of
JMW47_RS10870	COG0022	dehydrogenase e1 component
JMW47_RS10875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JMW47_RS10880	COG2390	Transcriptional regulator
JMW47_RS10890	COG0745	RESPONSE REGULATOR receiver
JMW47_RS10895	COG2205	protein histidine kinase activity
JMW47_RS10905	COG3507	Belongs to the glycosyl hydrolase 43 family
JMW47_RS10925	COG4956	integral membrane protein (PIN domain superfamily)
JMW47_RS10930	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JMW47_RS10935	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JMW47_RS10940	COG0542	response to heat
JMW47_RS10945	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JMW47_RS10950	COG3880	PFAM UvrB UvrC protein
JMW47_RS10955	COG4463	regulation of RNA biosynthetic process
JMW47_RS10960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMW47_RS10965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JMW47_RS11205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW47_RS11215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JMW47_RS11220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JMW47_RS11225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JMW47_RS11240	COG0590	tRNA wobble adenosine to inosine editing
JMW47_RS11245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMW47_RS11250	COG0668	transmembrane transport
JMW47_RS11255	COG1827	regulation of RNA biosynthetic process
JMW47_RS11305	COG1191	sigma factor activity
JMW47_RS11315	COG1366	Belongs to the anti-sigma-factor antagonist family
JMW47_RS11330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMW47_RS11335	COG0187	DNA topoisomerase II activity
JMW47_RS11340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JMW47_RS11350	COG0592	DNA-directed DNA polymerase activity
JMW47_RS11355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JMW47_RS11360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JMW47_RS11365	COG0594	ribonuclease P activity
JMW47_RS11370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JMW47_RS11375	COG0706	membrane insertase activity
JMW47_RS11380	COG1847	R3H domain protein
JMW47_RS11385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JMW47_RS11390	COG0445	tRNA wobble uridine modification
JMW47_RS11395	COG0357	Ribosomal RNA small subunit methyltransferase G
JMW47_RS11400	COG1475	DNA binding
JMW47_RS11405	COG1192	Involved in chromosome partitioning
JMW47_RS11410	COG1475	DNA binding
JMW47_RS11415	COG1104	cysteine desulfurase activity
JMW47_RS11430	COG0425	Belongs to the sulfur carrier protein TusA family
JMW47_RS11445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS11450	COG0360	Binds together with S18 to 16S ribosomal RNA
JMW47_RS11455	COG0629	single-stranded DNA binding
JMW47_RS11460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JMW47_RS11475	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JMW47_RS11480	COG0359	binds to the 23S rRNA
JMW47_RS11485	COG0305	Participates in initiation and elongation during chromosome replication
JMW47_RS11495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JMW47_RS11520	COG1484	DNA-dependent DNA replication
JMW47_RS11535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JMW47_RS11540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS11545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JMW47_RS11550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS11555	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW47_RS11560	COG2188	Transcriptional regulator
JMW47_RS11565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS11575	COG3964	amidohydrolase
JMW47_RS11590	COG1522	sequence-specific DNA binding
JMW47_RS11590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMW47_RS11595	COG0583	DNA-binding transcription factor activity
JMW47_RS11625	COG1335	isochorismatase
JMW47_RS11645	COG0517	IMP dehydrogenase activity
JMW47_RS11645	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JMW47_RS11650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW47_RS11665	COG1473	amidohydrolase
JMW47_RS11675	COG5002	protein histidine kinase activity
JMW47_RS11675	COG3447	MASE1 domain protein
JMW47_RS11675	COG5001	Diguanylate cyclase
JMW47_RS11685	COG1136	(ABC) transporter
JMW47_RS11685	COG0577	efflux transmembrane transporter activity
JMW47_RS11690	COG2824	Alkylphosphonate utilization operon protein PhnA
JMW47_RS11695	COG1357	PFAM Pentapeptide repeats (8 copies)
JMW47_RS11705	COG0519	Catalyzes the synthesis of GMP from XMP
JMW47_RS11715	COG5504	Zn-dependent protease
JMW47_RS11720	COG3263	regulation of cellular component size
JMW47_RS11725	COG0789	Transcriptional regulator
JMW47_RS11725	COG4978	Transcriptional regulator
JMW47_RS11740	COG0534	Mate efflux family protein
JMW47_RS11745	COG0346	lactoylglutathione lyase activity
JMW47_RS11755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JMW47_RS11765	COG3964	amidohydrolase
JMW47_RS11770	COG1141	Ferredoxin
JMW47_RS11785	COG1408	metallophosphoesterase
JMW47_RS11790	COG0037	tRNA processing
JMW47_RS11795	COG1876	peptidase activity
JMW47_RS11810	COG1854	S-ribosylhomocysteine lyase activity
JMW47_RS11820	COG0646	methionine synthase
JMW47_RS11820	COG1410	methionine synthase
JMW47_RS11840	COG0284	orotidine-5'-phosphate decarboxylase activity
JMW47_RS11850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JMW47_RS11860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JMW47_RS11875	COG1695	Transcriptional regulator
JMW47_RS11890	COG2205	protein histidine kinase activity
JMW47_RS11895	COG0577	efflux transmembrane transporter activity
JMW47_RS11895	COG1136	(ABC) transporter
JMW47_RS11905	COG4978	Transcriptional regulator
JMW47_RS11905	COG0789	Transcriptional regulator
JMW47_RS11910	COG0564	pseudouridine synthase activity
JMW47_RS11935	COG0626	cystathionine gamma-synthase activity
JMW47_RS11940	COG2223	nitrite transmembrane transporter activity
JMW47_RS11965	COG0653	protein targeting
JMW47_RS11995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JMW47_RS12000	COG1802	Transcriptional regulator
JMW47_RS12015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JMW47_RS12025	COG0037	tRNA processing
JMW47_RS12030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMW47_RS12040	COG3191	aminopeptidase activity
JMW47_RS12050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JMW47_RS12060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JMW47_RS12065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JMW47_RS12090	COG2155	Conserved Protein
JMW47_RS12095	COG1982	Orn Lys Arg decarboxylase major
JMW47_RS12105	COG0470	DNA polymerase III
JMW47_RS12110	COG1774	PSP1 C-terminal conserved region
JMW47_RS12115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JMW47_RS12120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JMW47_RS12125	COG0617	tRNA 3'-terminal CCA addition
JMW47_RS12130	COG1522	sequence-specific DNA binding
JMW47_RS12135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JMW47_RS12145	COG0700	Nucleoside recognition
JMW47_RS12150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW47_RS12150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW47_RS12155	COG0084	hydrolase, TatD family'
JMW47_RS12165	COG0613	PHP domain protein
JMW47_RS12170	COG3842	ATPase activity
JMW47_RS12185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMW47_RS12190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JMW47_RS12200	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW47_RS12205	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMW47_RS12215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JMW47_RS12220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMW47_RS12225	COG2088	sporulation resulting in formation of a cellular spore
JMW47_RS12230	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JMW47_RS12245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMW47_RS12295	COG0193	aminoacyl-tRNA hydrolase activity
JMW47_RS12300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JMW47_RS12305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMW47_RS12310	COG2002	toxin-antitoxin pair type II binding
JMW47_RS12315	COG2244	polysaccharide biosynthetic process
JMW47_RS12320	COG3956	TIGRFAM MazG family protein
JMW47_RS12330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JMW47_RS12350	COG0248	Ppx GppA phosphatase
JMW47_RS12355	COG2208	phosphoserine phosphatase activity
JMW47_RS12365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JMW47_RS12370	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JMW47_RS12375	COG0254	rRNA binding
JMW47_RS12380	COG3872	metal-dependent enzyme
JMW47_RS12385	COG2890	protein-(glutamine-N5) methyltransferase activity
JMW47_RS12390	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JMW47_RS12400	COG0009	L-threonylcarbamoyladenylate synthase
JMW47_RS12405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMW47_RS12410	COG0698	ribose 5-phosphate isomerase
JMW47_RS12415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JMW47_RS12420	COG3608	succinylglutamate desuccinylase aspartoacylase
JMW47_RS12420	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JMW47_RS12445	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMW47_RS12450	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JMW47_RS12455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMW47_RS12460	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JMW47_RS12465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JMW47_RS12470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JMW47_RS12475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JMW47_RS12480	COG0736	holo-[acyl-carrier-protein] synthase activity
JMW47_RS12485	COG0516	GMP reductase activity
JMW47_RS12485	COG0517	IMP dehydrogenase activity
JMW47_RS12505	COG2337	Toxic component of a toxin-antitoxin (TA) module
JMW47_RS12510	COG3959	Transketolase, thiamine diphosphate binding domain
JMW47_RS12515	COG3958	Transketolase
JMW47_RS12520	COG3949	Membrane
JMW47_RS12530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JMW47_RS12535	COG3409	Peptidoglycan-binding domain 1 protein
JMW47_RS12535	COG0793	Belongs to the peptidase S41A family
JMW47_RS12545	COG2188	Transcriptional regulator
JMW47_RS12555	COG0673	inositol 2-dehydrogenase activity
JMW47_RS12560	COG2222	sugar isomerase
JMW47_RS12565	COG0191	fructose-bisphosphate aldolase activity
JMW47_RS12570	COG3711	transcriptional antiterminator
JMW47_RS12575	COG1363	Peptidase, m42
JMW47_RS12580	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW47_RS12585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS12600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW47_RS12615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JMW47_RS12625	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JMW47_RS12635	COG1492	cobalamin metabolic process
JMW47_RS12640	COG1797	cobyrinic acid a,c-diamide synthase activity
JMW47_RS12650	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW47_RS12665	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JMW47_RS12705	COG0181	hydroxymethylbilane synthase activity
JMW47_RS12715	COG0113	porphobilinogen synthase activity
JMW47_RS12720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JMW47_RS12720	COG1648	precorrin-2 dehydrogenase activity
JMW47_RS12740	COG3842	ATPase activity
JMW47_RS12745	COG1175	transmembrane transport
JMW47_RS12755	COG1653	transport
JMW47_RS12765	COG0556	nucleotide-excision repair
JMW47_RS12775	COG0322	excinuclease ABC activity
JMW47_RS12805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMW47_RS12810	COG2116	formate transmembrane transporter activity
JMW47_RS12815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JMW47_RS12825	COG1660	Displays ATPase and GTPase activities
JMW47_RS12840	COG1481	regulation of sporulation
JMW47_RS12850	COG0205	6-phosphofructokinase activity
JMW47_RS12895	COG2199	diguanylate cyclase activity
JMW47_RS12900	COG4555	ABC transporter
JMW47_RS12920	COG0745	RESPONSE REGULATOR receiver
JMW47_RS12925	COG0488	(ABC) transporter
JMW47_RS12940	COG1733	regulation of RNA biosynthetic process
JMW47_RS12945	COG0778	Nitroreductase
JMW47_RS12955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS12970	COG0463	Glycosyl transferase, family 2
JMW47_RS12970	COG0457	Tetratricopeptide repeat
JMW47_RS13020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JMW47_RS13025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW47_RS13035	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW47_RS13035	COG0493	'glutamate synthase
JMW47_RS13055	COG2946	Replication initiation factor
JMW47_RS13110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JMW47_RS13125	COG0544	peptidyl-prolyl cis-trans isomerase activity
JMW47_RS13130	COG0740	serine-type endopeptidase activity
JMW47_RS13135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JMW47_RS13140	COG2059	Chromate
JMW47_RS13150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JMW47_RS13155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JMW47_RS13160	COG2814	Major facilitator Superfamily
JMW47_RS13175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMW47_RS13180	COG1459	type II secretion system
JMW47_RS13205	COG3012	SEC-C Motif Domain Protein
JMW47_RS13205	COG1405	negative regulation of cell septum assembly
JMW47_RS13220	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JMW47_RS13230	COG0166	Belongs to the GPI family
JMW47_RS13235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMW47_RS13250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMW47_RS13260	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS13260	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS13265	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS13265	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS13270	COG3715	PTS system
JMW47_RS13275	COG3716	PTS system mannose fructose sorbose family IID component
JMW47_RS13280	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JMW47_RS13305	COG1285	pathogenesis
JMW47_RS13310	COG1164	Oligoendopeptidase f
JMW47_RS13315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JMW47_RS13320	COG0745	RESPONSE REGULATOR receiver
JMW47_RS13335	COG0573	inorganic phosphate transmembrane transporter activity
JMW47_RS13340	COG0581	inorganic phosphate transmembrane transporter activity
JMW47_RS13345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JMW47_RS13350	COG0704	Plays a role in the regulation of phosphate uptake
JMW47_RS13365	COG0726	polysaccharide deacetylase
JMW47_RS13370	COG0525	valine-tRNA ligase activity
JMW47_RS13375	COG3279	Response regulator of the LytR AlgR family
JMW47_RS13385	COG0285	dihydrofolate synthase activity
JMW47_RS13410	COG0726	polysaccharide deacetylase
JMW47_RS13415	COG4656	Part of a membrane complex involved in electron transport
JMW47_RS13430	COG5275	peptidyl-tyrosine sulfation
JMW47_RS13430	COG0252	asparaginase activity
JMW47_RS13445	COG5275	peptidyl-tyrosine sulfation
JMW47_RS13445	COG0252	asparaginase activity
JMW47_RS13450	COG0252	asparaginase activity
JMW47_RS13450	COG5275	peptidyl-tyrosine sulfation
JMW47_RS13475	COG2226	methyltransferase
JMW47_RS13485	COG3829	transcription factor binding
JMW47_RS13490	COG3681	Belongs to the UPF0597 family
JMW47_RS13495	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JMW47_RS13505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JMW47_RS13515	COG2171	N-acyltransferase activity
JMW47_RS13520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JMW47_RS13525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW47_RS13530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JMW47_RS13535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW47_RS13540	COG1760	l-serine dehydratase
JMW47_RS13545	COG1473	amidohydrolase
JMW47_RS13555	COG2226	methyltransferase
JMW47_RS13560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JMW47_RS13570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMW47_RS13575	COG1732	Glycine betaine
JMW47_RS13610	COG0534	Mate efflux family protein
JMW47_RS13620	COG0778	Nitroreductase
JMW47_RS13630	COG0706	membrane insertase activity
JMW47_RS13635	COG0745	RESPONSE REGULATOR receiver
JMW47_RS13640	COG2205	protein histidine kinase activity
JMW47_RS13640	COG2770	Histidine kinase
JMW47_RS13665	COG0789	Transcriptional regulator
JMW47_RS13675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMW47_RS13700	COG0577	efflux transmembrane transporter activity
JMW47_RS13705	COG1136	(ABC) transporter
JMW47_RS13710	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS13710	COG2247	cell wall binding repeat
JMW47_RS13730	COG0789	Transcriptional regulator
JMW47_RS13735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JMW47_RS13745	COG0251	oxidation-reduction process
JMW47_RS13750	COG3829	transcription factor binding
JMW47_RS13765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JMW47_RS13770	COG0402	S-adenosylhomocysteine deaminase activity
JMW47_RS13780	COG0167	dihydroorotate dehydrogenase activity
JMW47_RS13790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW47_RS13795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JMW47_RS13800	COG2390	Transcriptional regulator
JMW47_RS13810	COG0126	phosphoglycerate kinase activity
JMW47_RS13815	COG0149	triose-phosphate isomerase activity
JMW47_RS13820	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JMW47_RS13825	COG0148	phosphopyruvate hydratase activity
JMW47_RS13855	COG1881	PFAM PEBP family protein
JMW47_RS13870	COG0557	exoribonuclease II activity
JMW47_RS13900	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JMW47_RS13955	COG0693	protein deglycase activity
JMW47_RS13975	COG3711	transcriptional antiterminator
JMW47_RS13980	COG2190	(PTS) system
JMW47_RS13980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS13980	COG1263	PTS System
JMW47_RS13985	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS13990	COG1840	ABC-type Fe3 transport system, periplasmic component
JMW47_RS14000	COG3842	ATPase activity
JMW47_RS14005	COG1178	ABC-type Fe3 transport system permease component
JMW47_RS14010	COG0191	fructose-bisphosphate aldolase activity
JMW47_RS14015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14020	COG3711	transcriptional antiterminator
JMW47_RS14025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14035	COG3711	transcriptional antiterminator
JMW47_RS14040	COG2190	(PTS) system
JMW47_RS14040	COG1263	PTS System
JMW47_RS14040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14045	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS14055	COG0640	Transcriptional regulator
JMW47_RS14065	COG1695	Transcriptional regulator
JMW47_RS14070	COG2223	nitrite transmembrane transporter activity
JMW47_RS14080	COG3620	sequence-specific DNA binding
JMW47_RS14085	COG1819	glycosyl
JMW47_RS14110	COG1136	(ABC) transporter
JMW47_RS14120	COG1263	PTS System
JMW47_RS14120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14120	COG2190	(PTS) system
JMW47_RS14125	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS14130	COG0778	Nitroreductase
JMW47_RS14135	COG1959	2 iron, 2 sulfur cluster binding
JMW47_RS14155	COG0205	6-phosphofructokinase activity
JMW47_RS14160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMW47_RS14165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW47_RS14170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14170	COG3711	transcriptional antiterminator
JMW47_RS14175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMW47_RS14180	COG1454	alcohol dehydrogenase
JMW47_RS14185	COG0561	phosphatase activity
JMW47_RS14190	COG2190	(PTS) system
JMW47_RS14195	COG0745	RESPONSE REGULATOR receiver
JMW47_RS14210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JMW47_RS14225	COG1136	(ABC) transporter
JMW47_RS14230	COG1132	(ABC) transporter
JMW47_RS14240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW47_RS14245	COG1263	PTS System
JMW47_RS14245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14250	COG1288	antiporter activity
JMW47_RS14260	COG3711	transcriptional antiterminator
JMW47_RS14265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14265	COG1263	PTS System
JMW47_RS14265	COG2190	(PTS) system
JMW47_RS14270	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS14275	COG2723	6-phospho-beta-galactosidase activity
JMW47_RS14285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JMW47_RS14295	COG0366	Alpha amylase catalytic
JMW47_RS14300	COG2188	Transcriptional regulator
JMW47_RS14305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14305	COG1263	PTS System
JMW47_RS14305	COG2190	(PTS) system
JMW47_RS14310	COG3394	polysaccharide catabolic process
JMW47_RS14330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14335	COG0191	fructose-bisphosphate aldolase activity
JMW47_RS14340	COG0366	Alpha amylase catalytic
JMW47_RS14370	COG3716	PTS system mannose fructose sorbose family IID component
JMW47_RS14375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14385	COG1940	carbohydrate kinase activity
JMW47_RS14390	COG1070	Carbohydrate kinase
JMW47_RS14410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14410	COG1263	PTS System
JMW47_RS14425	COG2190	(PTS) system
JMW47_RS14435	COG1136	(ABC) transporter
JMW47_RS14450	COG0642	Histidine kinase
JMW47_RS14455	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JMW47_RS14470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS14480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JMW47_RS14485	COG2971	BadF BadG BcrA BcrD
JMW47_RS14500	COG1737	Transcriptional regulator
JMW47_RS14515	COG2267	carboxylic ester hydrolase activity
JMW47_RS14535	COG0542	response to heat
JMW47_RS14555	COG0384	phenazine biosynthesis protein PhzF
JMW47_RS14565	COG3118	belongs to the thioredoxin family
JMW47_RS14570	COG0492	ferredoxin-NADP+ reductase activity
JMW47_RS14580	COG5002	protein histidine kinase activity
JMW47_RS14600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMW47_RS14620	COG4975	Glucose uptake
JMW47_RS14625	COG3711	transcriptional antiterminator
JMW47_RS14625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS14635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS14645	COG0383	alpha-mannosidase activity
JMW47_RS14650	COG1733	regulation of RNA biosynthetic process
JMW47_RS14655	COG0785	Cytochrome C biogenesis protein
JMW47_RS14660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMW47_RS14670	COG1376	ErfK ybiS ycfS ynhG family protein
JMW47_RS14675	COG1454	alcohol dehydrogenase
JMW47_RS14700	COG0179	Fumarylacetoacetate (FAA) hydrolase
JMW47_RS14705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW47_RS14715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW47_RS14720	COG1120	ATPase activity
JMW47_RS14730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMW47_RS14735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMW47_RS14755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW47_RS14770	COG0745	RESPONSE REGULATOR receiver
JMW47_RS14775	COG2205	protein histidine kinase activity
JMW47_RS14780	COG1968	undecaprenyl-diphosphatase activity
JMW47_RS14785	COG1136	(ABC) transporter
JMW47_RS14790	COG0577	efflux transmembrane transporter activity
JMW47_RS14820	COG1203	CRISPR-associated helicase, Cas3
JMW47_RS14835	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JMW47_RS14855	COG1268	BioY protein
JMW47_RS14865	COG0318	PFAM AMP-dependent synthetase and ligase
JMW47_RS14875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMW47_RS14885	COG1454	alcohol dehydrogenase
JMW47_RS14885	COG1012	belongs to the aldehyde dehydrogenase family
JMW47_RS14890	COG5001	Diguanylate cyclase
JMW47_RS14890	COG3300	MHYT domain
JMW47_RS14915	COG1269	ATP hydrolysis coupled proton transport
JMW47_RS14920	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMW47_RS14925	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
JMW47_RS14940	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
JMW47_RS14945	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
JMW47_RS14950	COG1394	ATPase activity, coupled to movement of substances
JMW47_RS14955	COG1840	ABC-type Fe3 transport system, periplasmic component
JMW47_RS14960	COG3842	ATPase activity
JMW47_RS14965	COG1178	ABC-type Fe3 transport system permease component
JMW47_RS14970	COG2188	Transcriptional regulator
JMW47_RS14980	COG1263	PTS System
JMW47_RS14980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS14985	COG0366	Alpha amylase catalytic
JMW47_RS14990	COG2188	Transcriptional regulator
JMW47_RS15000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW47_RS15005	COG1486	melibiose metabolic process
JMW47_RS15010	COG3394	polysaccharide catabolic process
JMW47_RS15015	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW47_RS15030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW47_RS15035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW47_RS15040	COG1120	ATPase activity
JMW47_RS15080	COG0312	modulator of DNA gyrase
JMW47_RS15085	COG0312	modulator of DNA gyrase
JMW47_RS15095	COG2267	carboxylic ester hydrolase activity
JMW47_RS15100	COG3829	transcription factor binding
JMW47_RS15100	COG3290	protein histidine kinase activity
JMW47_RS15120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JMW47_RS15125	COG1253	flavin adenine dinucleotide binding
JMW47_RS15130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW47_RS15140	COG0673	inositol 2-dehydrogenase activity
JMW47_RS15150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JMW47_RS15155	COG1696	Membrane protein involved in D-alanine export
JMW47_RS15160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMW47_RS15165	COG1349	DNA-binding transcription factor activity
JMW47_RS15170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JMW47_RS15170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW47_RS15175	COG1664	Polymer-forming cytoskeletal
JMW47_RS15185	COG0789	Transcriptional regulator
JMW47_RS15190	COG1592	Rubrerythrin
JMW47_RS15200	COG0604	alcohol dehydrogenase
JMW47_RS15215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMW47_RS15230	COG3949	Membrane
JMW47_RS15235	COG1473	amidohydrolase
JMW47_RS15240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JMW47_RS15245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMW47_RS15255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMW47_RS15270	COG0697	spore germination
JMW47_RS15275	COG0436	Aminotransferase
JMW47_RS15310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JMW47_RS15320	COG1132	(ABC) transporter
JMW47_RS15340	COG2084	Dehydrogenase
JMW47_RS15345	COG2610	gluconate transmembrane transporter activity
JMW47_RS15380	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JMW47_RS15385	COG0632	four-way junction helicase activity
JMW47_RS15390	COG2255	four-way junction helicase activity
JMW47_RS15395	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JMW47_RS15405	COG0343	queuine tRNA-ribosyltransferase activity
JMW47_RS15425	COG2247	cell wall binding repeat
JMW47_RS15425	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15450	COG0653	protein targeting
JMW47_RS15465	COG2247	cell wall binding repeat
JMW47_RS15465	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15470	COG2246	polysaccharide biosynthetic process
JMW47_RS15480	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15480	COG2247	cell wall binding repeat
JMW47_RS15490	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JMW47_RS15500	COG2247	cell wall binding repeat
JMW47_RS15500	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15505	COG0728	peptidoglycan biosynthetic process
JMW47_RS15510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW47_RS15530	COG1216	Glycosyl transferase, family 2
JMW47_RS15535	COG1215	transferase activity, transferring glycosyl groups
JMW47_RS15535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMW47_RS15540	COG1215	transferase activity, transferring glycosyl groups
JMW47_RS15550	COG1215	transferase activity, transferring glycosyl groups
JMW47_RS15555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JMW47_RS15560	COG0438	transferase activity, transferring glycosyl groups
JMW47_RS15570	COG0791	NLP P60 protein
JMW47_RS15575	COG1649	PFAM Uncharacterised BCR, COG1649
JMW47_RS15580	COG1316	TRANSCRIPTIONal
JMW47_RS15585	COG1316	TRANSCRIPTIONal
JMW47_RS15590	COG0561	phosphatase activity
JMW47_RS15600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JMW47_RS15605	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS15675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JMW47_RS15675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JMW47_RS15680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMW47_RS15685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JMW47_RS15690	COG1490	D-aminoacyl-tRNA deacylase activity
JMW47_RS15695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMW47_RS15700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JMW47_RS15705	COG0124	histidyl-tRNA synthetase
JMW47_RS15710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JMW47_RS15720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JMW47_RS15725	COG0583	DNA-binding transcription factor activity
JMW47_RS15730	COG2247	cell wall binding repeat
JMW47_RS15730	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS15740	COG1757	Na H antiporter
JMW47_RS15745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW47_RS15775	COG1937	Protein conserved in bacteria
JMW47_RS15795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMW47_RS15800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW47_RS15815	COG0745	RESPONSE REGULATOR receiver
JMW47_RS15820	COG0642	Histidine kinase
JMW47_RS15820	COG5002	protein histidine kinase activity
JMW47_RS15825	COG3069	C4-dicarboxylate transmembrane transporter activity
JMW47_RS15830	COG0726	polysaccharide deacetylase
JMW47_RS15850	COG4509	Sortase family
JMW47_RS15875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JMW47_RS15880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JMW47_RS15885	COG1376	ErfK ybiS ycfS ynhG family protein
JMW47_RS15895	COG0583	DNA-binding transcription factor activity
JMW47_RS15915	COG2271	Major facilitator Superfamily
JMW47_RS15925	COG0402	S-adenosylhomocysteine deaminase activity
JMW47_RS15930	COG2252	PERMEase
JMW47_RS15965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW47_RS15970	COG2502	aspartate--ammonia ligase
JMW47_RS15990	COG1388	LysM domain
JMW47_RS15990	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW47_RS16025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW47_RS16035	COG0671	phosphoesterase, PA-phosphatase related
JMW47_RS16040	COG2081	HI0933 family
JMW47_RS16075	COG4869	propanediol catabolic process
JMW47_RS16085	COG2340	Cysteine-rich secretory protein family
JMW47_RS16090	COG2610	gluconate transmembrane transporter activity
JMW47_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
JMW47_RS16105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JMW47_RS16110	COG0183	Belongs to the thiolase family
JMW47_RS16115	COG0583	DNA-binding transcription factor activity
JMW47_RS16120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMW47_RS16125	COG0601	transmembrane transport
JMW47_RS16135	COG0444	Belongs to the ABC transporter superfamily
JMW47_RS16140	COG4608	Belongs to the ABC transporter superfamily
JMW47_RS16145	COG0025	NhaP-type Na H and K H
JMW47_RS16150	COG3711	transcriptional antiterminator
JMW47_RS16155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS16155	COG2190	(PTS) system
JMW47_RS16155	COG1263	PTS System
JMW47_RS16165	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMW47_RS16170	COG3300	MHYT domain
JMW47_RS16170	COG5001	Diguanylate cyclase
JMW47_RS16175	COG0012	GTP binding
JMW47_RS16185	COG0612	Peptidase, M16
JMW47_RS16190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JMW47_RS16195	COG0275	rRNA processing
JMW47_RS16205	COG0768	penicillin binding
JMW47_RS16210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JMW47_RS16215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMW47_RS16220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMW47_RS16225	COG0772	Belongs to the SEDS family
JMW47_RS16230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW47_RS16250	COG3856	small basic protein
JMW47_RS16255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JMW47_RS16270	COG1191	sigma factor activity
JMW47_RS16275	COG1191	sigma factor activity
JMW47_RS16280	COG1873	PFAM PRC-barrel domain
JMW47_RS16285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JMW47_RS16295	COG0745	RESPONSE REGULATOR receiver
JMW47_RS16300	COG5002	protein histidine kinase activity
JMW47_RS16325	COG1160	GTP binding
JMW47_RS16330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JMW47_RS16335	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JMW47_RS16355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JMW47_RS16365	COG3830	Belongs to the UPF0237 family
JMW47_RS16385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JMW47_RS16390	COG1799	cell septum assembly
JMW47_RS16400	COG2302	S4 RNA-binding domain
JMW47_RS16410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JMW47_RS16415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW47_RS16430	COG1307	EDD domain protein, DegV family
JMW47_RS16435	COG0006	proline dipeptidase activity
JMW47_RS16440	COG0531	amino acid
JMW47_RS16445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JMW47_RS16470	COG3275	phosphorelay sensor kinase activity
JMW47_RS16475	COG3279	Response regulator of the LytR AlgR family
JMW47_RS16480	COG1966	Carbon starvation protein
JMW47_RS16485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JMW47_RS16495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JMW47_RS16500	COG0564	pseudouridine synthase activity
JMW47_RS16505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JMW47_RS16515	COG0488	(ABC) transporter
JMW47_RS16520	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JMW47_RS16530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JMW47_RS16535	COG1561	YicC-like family, N-terminal region
JMW47_RS16540	COG0194	GDP metabolic process
JMW47_RS16545	COG1758	RNA polymerase activity
JMW47_RS16550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMW47_RS16555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JMW47_RS16560	COG0242	peptide deformylase activity
JMW47_RS16565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JMW47_RS16575	COG2738	Putative neutral zinc metallopeptidase
JMW47_RS16580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMW47_RS16580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMW47_RS16585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JMW47_RS16595	COG2815	serine threonine protein kinase
JMW47_RS16595	COG0515	serine threonine protein kinase
JMW47_RS16600	COG1028	Short-chain dehydrogenase reductase Sdr
JMW47_RS16605	COG1162	GTPase activity
JMW47_RS16610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMW47_RS16615	COG1564	THIamine pyrophosphokinase
JMW47_RS16635	COG5002	protein histidine kinase activity
JMW47_RS16640	COG0383	alpha-mannosidase activity
JMW47_RS16645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS16650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS16650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS16650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS16655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS16655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS16655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS16660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS16660	COG3711	transcriptional antiterminator
JMW47_RS16665	COG0789	Transcriptional regulator
JMW47_RS16680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JMW47_RS16685	COG1302	Protein conserved in bacteria
JMW47_RS16690	COG1461	Dihydroxyacetone kinase
JMW47_RS16695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JMW47_RS16700	COG0742	ribosomal rna small subunit methyltransferase
JMW47_RS16725	COG0395	ABC-type sugar transport system, permease component
JMW47_RS16745	COG4124	Belongs to the glycosyl hydrolase 26 family
JMW47_RS16745	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JMW47_RS16770	COG1823	symporter activity
JMW47_RS16775	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMW47_RS16780	COG1234	tRNA 3'-trailer cleavage
JMW47_RS16790	COG0737	Belongs to the 5'-nucleotidase family
JMW47_RS16795	COG0745	RESPONSE REGULATOR receiver
JMW47_RS16805	COG1136	(ABC) transporter
JMW47_RS16805	COG0577	efflux transmembrane transporter activity
JMW47_RS16850	COG1309	transcriptional regulator
JMW47_RS16855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JMW47_RS16860	COG2137	regulation of response to DNA damage stimulus
JMW47_RS16865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JMW47_RS16870	COG1713	HD superfamily hydrolase involved in NAD metabolism
JMW47_RS16875	COG0799	negative regulation of ribosome biogenesis
JMW47_RS16880	COG0495	leucyl-tRNA aminoacylation
JMW47_RS16920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JMW47_RS16925	COG0251	oxidation-reduction process
JMW47_RS16930	COG1263	PTS System
JMW47_RS16930	COG2190	(PTS) system
JMW47_RS16930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS16935	COG3711	transcriptional antiterminator
JMW47_RS16940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW47_RS16940	COG1263	PTS System
JMW47_RS16960	COG2814	Major facilitator Superfamily
JMW47_RS16965	COG1309	transcriptional regulator
JMW47_RS16970	COG1876	peptidase activity
JMW47_RS16975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW47_RS16980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW47_RS16985	COG0561	phosphatase activity
JMW47_RS16990	COG0165	Argininosuccinate lyase
JMW47_RS17000	COG1686	Belongs to the peptidase S11 family
JMW47_RS17025	COG5002	protein histidine kinase activity
JMW47_RS17030	COG1482	cell wall glycoprotein biosynthetic process
JMW47_RS17035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW47_RS17040	COG3711	transcriptional antiterminator
JMW47_RS17040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS17050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS17055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS17060	COG0006	proline dipeptidase activity
JMW47_RS17065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW47_RS17070	COG1396	sequence-specific DNA binding
JMW47_RS17090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JMW47_RS17095	COG1388	LysM domain
JMW47_RS17095	COG3584	3D domain protein
JMW47_RS17105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JMW47_RS17110	COG2333	competence protein COMEC
JMW47_RS17110	COG0658	competence protein
JMW47_RS17125	COG2333	competence protein COMEC
JMW47_RS17125	COG0658	competence protein
JMW47_RS17135	COG0268	Binds directly to 16S ribosomal RNA
JMW47_RS17160	COG0481	GTPase activity
JMW47_RS17165	COG0617	tRNA 3'-terminal CCA addition
JMW47_RS17170	COG0531	amino acid
JMW47_RS17175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JMW47_RS17180	COG1420	regulation of RNA biosynthetic process
JMW47_RS17185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JMW47_RS17190	COG0443	Heat shock 70 kDa protein
JMW47_RS17195	COG0484	heat shock protein binding
JMW47_RS17205	COG0477	Major facilitator Superfamily
JMW47_RS17210	COG2508	Transcriptional regulator
JMW47_RS17215	COG3842	ATPase activity
JMW47_RS17250	COG2264	protein methyltransferase activity
JMW47_RS17255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JMW47_RS17260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW47_RS17265	COG0537	adenosine 5'-monophosphoramidase activity
JMW47_RS17270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JMW47_RS17275	COG1610	YqeY-like protein
JMW47_RS17280	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JMW47_RS17285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMW47_RS17300	COG1702	phosphate starvation-inducible protein PhoH
JMW47_RS17305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JMW47_RS17310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JMW47_RS17315	COG0295	cytidine deaminase activity
JMW47_RS17320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JMW47_RS17325	COG2239	Acts as a magnesium transporter
JMW47_RS17335	COG1381	Involved in DNA repair and RecF pathway recombination
JMW47_RS17345	COG0752	glycyl-tRNA synthetase alpha subunit
JMW47_RS17350	COG0751	glycine-tRNA ligase activity
JMW47_RS17360	COG1414	Transcriptional regulator
JMW47_RS17370	COG0674	pyruvate-flavodoxin oxidoreductase activity
JMW47_RS17370	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JMW47_RS17390	COG0280	phosphate acetyltransferase
JMW47_RS17395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS17400	COG2223	nitrite transmembrane transporter activity
JMW47_RS17405	COG1115	amino acid carrier protein
JMW47_RS17415	COG1288	antiporter activity
JMW47_RS17425	COG2207	Transcriptional regulator
JMW47_RS17435	COG3732	PTS system glucitol sorbitol-specific
JMW47_RS17440	COG3711	transcriptional antiterminator
JMW47_RS17440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS17460	COG0517	IMP dehydrogenase activity
JMW47_RS17465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JMW47_RS17470	COG0574	Belongs to the PEP-utilizing enzyme family
JMW47_RS17470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JMW47_RS17500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMW47_RS17500	COG0551	DNA topoisomerase type I activity
JMW47_RS17510	COG0791	NLP P60 protein
JMW47_RS17510	COG3103	Sh3 type 3 domain protein
JMW47_RS17510	COG1388	LysM domain
JMW47_RS17515	COG3546	catalase activity
JMW47_RS17530	COG0037	tRNA processing
JMW47_RS17550	COG2176	DNA-directed DNA polymerase activity
JMW47_RS17555	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JMW47_RS17560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW47_RS17560	COG0072	phenylalanine-tRNA ligase activity
JMW47_RS17620	COG2203	Gaf domain
JMW47_RS17620	COG2199	diguanylate cyclase activity
JMW47_RS17625	COG2199	diguanylate cyclase activity
JMW47_RS17650	COG3426	butyrate kinase activity
JMW47_RS17655	COG2364	Membrane
JMW47_RS17665	COG0628	permease
JMW47_RS17680	COG1966	Carbon starvation protein
JMW47_RS17685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JMW47_RS17695	COG0157	Belongs to the NadC ModD family
JMW47_RS17735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW47_RS17745	COG1116	anion transmembrane transporter activity
JMW47_RS17760	COG0561	phosphatase activity
JMW47_RS17780	COG3118	belongs to the thioredoxin family
JMW47_RS17810	COG0006	proline dipeptidase activity
JMW47_RS17820	COG0583	DNA-binding transcription factor activity
JMW47_RS17825	COG2985	domain, Protein
JMW47_RS17825	COG2985	domain, Protein
JMW47_RS17825	COG0490	domain, Protein
JMW47_RS17825	COG0490	domain, Protein
JMW47_RS17830	COG0427	acetyl-CoA hydrolase
JMW47_RS17835	COG1012	belongs to the aldehyde dehydrogenase family
JMW47_RS17850	COG0427	acetyl-CoA hydrolase
JMW47_RS17855	COG1454	alcohol dehydrogenase
JMW47_RS17865	COG3853	Toxic anion resistance protein (TelA)
JMW47_RS17870	COG0517	IMP dehydrogenase activity
JMW47_RS17870	COG0516	GMP reductase activity
JMW47_RS17880	COG3711	transcriptional antiterminator
JMW47_RS17885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS17890	COG0246	Mannitol dehydrogenase
JMW47_RS17895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMW47_RS17900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMW47_RS17905	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS17905	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS17915	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW47_RS17920	COG3775	system Galactitol-specific IIC component
JMW47_RS17925	COG1063	alcohol dehydrogenase
JMW47_RS17935	COG3959	Transketolase, thiamine diphosphate binding domain
JMW47_RS17940	COG3958	Transketolase
JMW47_RS17945	COG0698	ribose 5-phosphate isomerase
JMW47_RS17950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMW47_RS17955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW47_RS18005	COG3620	sequence-specific DNA binding
JMW47_RS18060	COG5002	protein histidine kinase activity
JMW47_RS18070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JMW47_RS18075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW47_RS18095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW47_RS18095	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW47_RS18100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS18100	COG2213	PTS system mannitol-specific
JMW47_RS18105	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW47_RS18110	COG3775	system Galactitol-specific IIC component
JMW47_RS18115	COG1063	alcohol dehydrogenase
JMW47_RS18120	COG0235	Class ii aldolase
JMW47_RS18125	COG0235	Class ii aldolase
JMW47_RS18130	COG1115	amino acid carrier protein
JMW47_RS18150	COG2365	Tyrosine phosphatase family
JMW47_RS18155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS18155	COG3711	transcriptional antiterminator
JMW47_RS18160	COG1105	Belongs to the carbohydrate kinase PfkB family
JMW47_RS18165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS18165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW47_RS18165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW47_RS18175	COG0723	plastoquinol--plastocyanin reductase activity
JMW47_RS18175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JMW47_RS18190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMW47_RS18195	COG3104	oligopeptide transport
JMW47_RS18200	COG0006	proline dipeptidase activity
JMW47_RS18205	COG3104	oligopeptide transport
JMW47_RS18210	COG0662	Cupin 2, conserved barrel domain protein
JMW47_RS18240	COG1509	lysine 2,3-aminomutase activity
JMW47_RS18255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMW47_RS18265	COG1404	Belongs to the peptidase S8 family
JMW47_RS18280	COG0017	Asparaginyl-tRNA synthetase
JMW47_RS18285	COG2203	Gaf domain
JMW47_RS18285	COG5001	Diguanylate cyclase
JMW47_RS18285	COG4251	negative regulation of phosphorylation
JMW47_RS18285	COG3706	GGDEF domain
JMW47_RS18300	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JMW47_RS18305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW47_RS18310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMW47_RS18370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW47_RS18380	COG0710	3-dehydroquinate dehydratase activity
JMW47_RS18400	COG0288	reversible hydration of carbon dioxide
JMW47_RS18420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMW47_RS18435	COG1012	belongs to the aldehyde dehydrogenase family
JMW47_RS18440	COG0628	permease
JMW47_RS18445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JMW47_RS18450	COG1309	transcriptional regulator
JMW47_RS18465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW47_RS18475	COG0674	pyruvate-flavodoxin oxidoreductase activity
JMW47_RS18475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JMW47_RS18495	COG1528	Iron-storage protein
JMW47_RS18515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family