locus-tag	class	description
JMW51_RS00015	COG1131	(ABC) transporter
JMW51_RS00035	COG0745	RESPONSE REGULATOR receiver
JMW51_RS00040	COG5002	protein histidine kinase activity
JMW51_RS00060	COG3973	AAA domain
JMW51_RS00070	COG1051	belongs to the nudix hydrolase family
JMW51_RS00085	COG1757	Na H antiporter
JMW51_RS00090	COG3457	Alanine racemase
JMW51_RS00120	COG3804	dihydrodipicolinate reductase
JMW51_RS00125	COG3829	transcription factor binding
JMW51_RS00135	COG0626	cystathionine gamma-synthase activity
JMW51_RS00155	COG3254	rhamnose metabolic process
JMW51_RS00170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW51_RS00180	COG0745	RESPONSE REGULATOR receiver
JMW51_RS00185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW51_RS00235	COG1187	pseudouridine synthase activity
JMW51_RS00245	COG0191	fructose-bisphosphate aldolase activity
JMW51_RS00250	COG3829	transcription factor binding
JMW51_RS00255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW51_RS00260	COG2086	electron transfer activity
JMW51_RS00265	COG1960	acyl-CoA dehydrogenase activity
JMW51_RS00290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMW51_RS00305	COG0367	asparagine synthase
JMW51_RS00310	COG3711	transcriptional antiterminator
JMW51_RS00315	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS00320	COG1263	PTS System
JMW51_RS00320	COG2190	(PTS) system
JMW51_RS00320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS00345	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JMW51_RS00365	COG2357	RelA SpoT domain protein
JMW51_RS00370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMW51_RS00430	COG2226	methyltransferase
JMW51_RS00450	COG1136	(ABC) transporter
JMW51_RS00460	COG1012	belongs to the aldehyde dehydrogenase family
JMW51_RS00460	COG1454	alcohol dehydrogenase
JMW51_RS00475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JMW51_RS00485	COG1362	aminopeptidase activity
JMW51_RS00490	COG0210	DNA helicase
JMW51_RS00495	COG1122	ATPase activity
JMW51_RS00505	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
JMW51_RS00525	COG0586	Pfam SNARE associated Golgi protein
JMW51_RS00545	COG2217	Heavy metal translocating P-type atpase
JMW51_RS00585	COG1473	amidohydrolase
JMW51_RS00595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW51_RS00600	COG1172	Belongs to the binding-protein-dependent transport system permease family
JMW51_RS00605	COG1129	ABC transporter
JMW51_RS00610	COG1879	ABC-type sugar transport system periplasmic component
JMW51_RS00615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMW51_RS00625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JMW51_RS00645	COG1131	(ABC) transporter
JMW51_RS00665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW51_RS00675	COG3716	PTS system mannose fructose sorbose family IID component
JMW51_RS00700	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS00700	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS00705	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS00705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS00710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW51_RS00725	COG1733	regulation of RNA biosynthetic process
JMW51_RS00740	COG1533	DNA photolyase activity
JMW51_RS00745	COG1454	alcohol dehydrogenase
JMW51_RS00790	COG1215	transferase activity, transferring glycosyl groups
JMW51_RS00800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JMW51_RS00810	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JMW51_RS00825	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JMW51_RS00830	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JMW51_RS00865	COG0741	lytic transglycosylase activity
JMW51_RS00870	COG1088	dTDP-glucose 4,6-dehydratase activity
JMW51_RS00880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JMW51_RS00895	COG0138	bifunctional purine biosynthesis protein purh
JMW51_RS00900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JMW51_RS00905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JMW51_RS00910	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JMW51_RS00915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JMW51_RS00920	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JMW51_RS00925	COG0778	Nitroreductase
JMW51_RS00940	COG1011	Hydrolase
JMW51_RS00950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS00955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS00970	COG2200	EAL domain
JMW51_RS00970	COG2771	luxR family
JMW51_RS00975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMW51_RS01030	COG0519	Catalyzes the synthesis of GMP from XMP
JMW51_RS01030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JMW51_RS01035	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JMW51_RS01040	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JMW51_RS01045	COG1691	(AIR) carboxylase
JMW51_RS01050	COG0459	protein refolding
JMW51_RS01055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JMW51_RS01060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMW51_RS01075	COG0583	DNA-binding transcription factor activity
JMW51_RS01085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JMW51_RS01090	COG0167	dihydroorotate dehydrogenase activity
JMW51_RS01095	COG0543	2 iron, 2 sulfur cluster binding
JMW51_RS01100	COG0540	Belongs to the ATCase OTCase family
JMW51_RS01140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JMW51_RS01155	COG1151	hydroxylamine reductase activity
JMW51_RS01165	COG2221	Nitrite and sulphite reductase 4Fe-4S
JMW51_RS01175	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JMW51_RS01180	COG0488	(ABC) transporter
JMW51_RS01185	COG0534	Mate efflux family protein
JMW51_RS01215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMW51_RS01225	COG1882	Formate acetyltransferase
JMW51_RS01230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMW51_RS01235	COG0456	acetyltransferase
JMW51_RS01240	COG1214	PFAM Peptidase M22, glycoprotease
JMW51_RS01245	COG0802	atpase or kinase
JMW51_RS01260	COG1228	amidohydrolase
JMW51_RS01265	COG2183	response to ionizing radiation
JMW51_RS01275	COG0653	protein targeting
JMW51_RS01280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMW51_RS01290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW51_RS01295	COG1446	asparaginase
JMW51_RS01305	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS01310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS01315	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW51_RS01320	COG3711	transcriptional antiterminator
JMW51_RS01320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS01325	COG1040	competence protein
JMW51_RS01330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JMW51_RS01335	COG3949	Membrane
JMW51_RS01340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JMW51_RS01350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JMW51_RS01355	COG1077	Cell shape determining protein MreB Mrl
JMW51_RS01360	COG1609	Transcriptional regulator
JMW51_RS01370	COG2385	sporulation resulting in formation of a cellular spore
JMW51_RS01375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMW51_RS01385	COG2897	thiosulfate sulfurtransferase activity
JMW51_RS01390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JMW51_RS01395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW51_RS01430	COG0280	phosphate acetyltransferase
JMW51_RS01440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JMW51_RS01685	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS01690	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JMW51_RS01695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JMW51_RS01700	COG0101	tRNA pseudouridine synthase activity
JMW51_RS01705	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JMW51_RS01710	COG1122	ATPase activity
JMW51_RS01715	COG1122	ATPase activity
JMW51_RS01720	COG0203	ribosomal protein L17
JMW51_RS01725	COG0202	RNA polymerase activity
JMW51_RS01730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JMW51_RS01735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JMW51_RS01740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JMW51_RS01745	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JMW51_RS01750	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JMW51_RS01760	COG0024	Methionine aminopeptidase
JMW51_RS01765	COG0563	adenylate kinase activity
JMW51_RS01775	COG0200	Binds to the 23S rRNA
JMW51_RS01780	COG1841	ribosomal large subunit assembly
JMW51_RS01785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JMW51_RS01790	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JMW51_RS01795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JMW51_RS01800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JMW51_RS01805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMW51_RS01810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JMW51_RS01815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JMW51_RS01820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JMW51_RS01825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JMW51_RS01830	COG0255	Belongs to the universal ribosomal protein uL29 family
JMW51_RS01835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JMW51_RS01840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JMW51_RS01845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JMW51_RS01850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JMW51_RS01855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JMW51_RS01860	COG0089	rRNA binding
JMW51_RS01865	COG0088	Forms part of the polypeptide exit tunnel
JMW51_RS01870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JMW51_RS01875	COG0051	transcription antitermination factor activity, RNA binding
JMW51_RS01880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMW51_RS01885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMW51_RS01890	COG0049	tRNA binding
JMW51_RS01895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JMW51_RS01900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMW51_RS01905	COG0085	RNA polymerase activity
JMW51_RS01915	COG0222	ribosome binding
JMW51_RS01920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JMW51_RS01925	COG0081	regulation of translation
JMW51_RS01930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JMW51_RS01935	COG0250	Participates in transcription elongation, termination and antitermination
JMW51_RS01945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JMW51_RS01950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMW51_RS01960	COG3688	RNA-binding protein containing a PIN domain
JMW51_RS01965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMW51_RS01980	COG0215	cysteine-tRNA ligase activity
JMW51_RS01990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMW51_RS01995	COG0442	prolyl-tRNA aminoacylation
JMW51_RS02000	COG0442	prolyl-tRNA aminoacylation
JMW51_RS02005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JMW51_RS02010	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JMW51_RS02015	COG0095	Lipoate-protein ligase
JMW51_RS02030	COG3775	system Galactitol-specific IIC component
JMW51_RS02035	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW51_RS02045	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS02045	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS02050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMW51_RS02055	COG0508	dehydrogenase complex catalyzes the overall conversion of
JMW51_RS02060	COG0022	dehydrogenase e1 component
JMW51_RS02065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JMW51_RS02070	COG2390	Transcriptional regulator
JMW51_RS02080	COG0745	RESPONSE REGULATOR receiver
JMW51_RS02085	COG2205	protein histidine kinase activity
JMW51_RS02095	COG3507	Belongs to the glycosyl hydrolase 43 family
JMW51_RS02115	COG4956	integral membrane protein (PIN domain superfamily)
JMW51_RS02120	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JMW51_RS02125	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JMW51_RS02130	COG0542	response to heat
JMW51_RS02135	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JMW51_RS02140	COG3880	PFAM UvrB UvrC protein
JMW51_RS02145	COG4463	regulation of RNA biosynthetic process
JMW51_RS02150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMW51_RS02155	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JMW51_RS02395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW51_RS02405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JMW51_RS02410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JMW51_RS02415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JMW51_RS02430	COG0590	tRNA wobble adenosine to inosine editing
JMW51_RS02435	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMW51_RS02440	COG0668	transmembrane transport
JMW51_RS02445	COG1827	regulation of RNA biosynthetic process
JMW51_RS02495	COG1191	sigma factor activity
JMW51_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
JMW51_RS02520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMW51_RS02525	COG0187	DNA topoisomerase II activity
JMW51_RS02530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JMW51_RS02540	COG0592	DNA-directed DNA polymerase activity
JMW51_RS02545	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JMW51_RS02550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JMW51_RS02555	COG0594	ribonuclease P activity
JMW51_RS02560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JMW51_RS02565	COG0706	membrane insertase activity
JMW51_RS02570	COG1847	R3H domain protein
JMW51_RS02575	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JMW51_RS02580	COG0445	tRNA wobble uridine modification
JMW51_RS02585	COG0357	Ribosomal RNA small subunit methyltransferase G
JMW51_RS02590	COG1475	DNA binding
JMW51_RS02595	COG1192	Involved in chromosome partitioning
JMW51_RS02600	COG1475	DNA binding
JMW51_RS02605	COG1104	cysteine desulfurase activity
JMW51_RS02620	COG0425	Belongs to the sulfur carrier protein TusA family
JMW51_RS02635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS02640	COG0360	Binds together with S18 to 16S ribosomal RNA
JMW51_RS02645	COG0629	single-stranded DNA binding
JMW51_RS02650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JMW51_RS02665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JMW51_RS02670	COG0359	binds to the 23S rRNA
JMW51_RS02675	COG0305	Participates in initiation and elongation during chromosome replication
JMW51_RS02685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JMW51_RS02710	COG1484	DNA-dependent DNA replication
JMW51_RS02725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JMW51_RS02730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS02735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JMW51_RS02740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS02745	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW51_RS02750	COG2188	Transcriptional regulator
JMW51_RS02755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS02765	COG3964	amidohydrolase
JMW51_RS02780	COG1522	sequence-specific DNA binding
JMW51_RS02780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMW51_RS02785	COG0583	DNA-binding transcription factor activity
JMW51_RS02815	COG1335	isochorismatase
JMW51_RS02835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JMW51_RS02835	COG0517	IMP dehydrogenase activity
JMW51_RS02840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW51_RS02855	COG1473	amidohydrolase
JMW51_RS02865	COG3447	MASE1 domain protein
JMW51_RS02865	COG5001	Diguanylate cyclase
JMW51_RS02865	COG5002	protein histidine kinase activity
JMW51_RS02875	COG1136	(ABC) transporter
JMW51_RS02875	COG0577	efflux transmembrane transporter activity
JMW51_RS02880	COG2824	Alkylphosphonate utilization operon protein PhnA
JMW51_RS02885	COG1357	PFAM Pentapeptide repeats (8 copies)
JMW51_RS02895	COG0519	Catalyzes the synthesis of GMP from XMP
JMW51_RS02905	COG5504	Zn-dependent protease
JMW51_RS02910	COG3263	regulation of cellular component size
JMW51_RS02915	COG4978	Transcriptional regulator
JMW51_RS02915	COG0789	Transcriptional regulator
JMW51_RS02930	COG0534	Mate efflux family protein
JMW51_RS02935	COG0346	lactoylglutathione lyase activity
JMW51_RS02945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JMW51_RS02955	COG3964	amidohydrolase
JMW51_RS02960	COG1141	Ferredoxin
JMW51_RS02975	COG1408	metallophosphoesterase
JMW51_RS02980	COG0037	tRNA processing
JMW51_RS02985	COG1876	peptidase activity
JMW51_RS03000	COG1854	S-ribosylhomocysteine lyase activity
JMW51_RS03010	COG0646	methionine synthase
JMW51_RS03010	COG1410	methionine synthase
JMW51_RS03030	COG0284	orotidine-5'-phosphate decarboxylase activity
JMW51_RS03040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JMW51_RS03050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JMW51_RS03065	COG1695	Transcriptional regulator
JMW51_RS03075	COG2205	protein histidine kinase activity
JMW51_RS03080	COG1136	(ABC) transporter
JMW51_RS03080	COG0577	efflux transmembrane transporter activity
JMW51_RS03090	COG0789	Transcriptional regulator
JMW51_RS03090	COG4978	Transcriptional regulator
JMW51_RS03095	COG0564	pseudouridine synthase activity
JMW51_RS03120	COG0626	cystathionine gamma-synthase activity
JMW51_RS03125	COG2223	nitrite transmembrane transporter activity
JMW51_RS03150	COG0653	protein targeting
JMW51_RS03180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JMW51_RS03185	COG1802	Transcriptional regulator
JMW51_RS03200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JMW51_RS03210	COG0037	tRNA processing
JMW51_RS03215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMW51_RS03225	COG3191	aminopeptidase activity
JMW51_RS03235	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JMW51_RS03245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JMW51_RS03250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JMW51_RS03275	COG2155	Conserved Protein
JMW51_RS03280	COG1982	Orn Lys Arg decarboxylase major
JMW51_RS03290	COG0470	DNA polymerase III
JMW51_RS03295	COG1774	PSP1 C-terminal conserved region
JMW51_RS03300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JMW51_RS03305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JMW51_RS03310	COG0617	tRNA 3'-terminal CCA addition
JMW51_RS03315	COG1522	sequence-specific DNA binding
JMW51_RS03320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JMW51_RS03330	COG0700	Nucleoside recognition
JMW51_RS03335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW51_RS03335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW51_RS03340	COG0084	hydrolase, TatD family'
JMW51_RS03350	COG0613	PHP domain protein
JMW51_RS03355	COG3842	ATPase activity
JMW51_RS03370	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMW51_RS03375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JMW51_RS03385	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW51_RS03390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMW51_RS03400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JMW51_RS03405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMW51_RS03410	COG2088	sporulation resulting in formation of a cellular spore
JMW51_RS03415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JMW51_RS03430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMW51_RS03480	COG0193	aminoacyl-tRNA hydrolase activity
JMW51_RS03485	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JMW51_RS03490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMW51_RS03495	COG2002	toxin-antitoxin pair type II binding
JMW51_RS03500	COG2244	polysaccharide biosynthetic process
JMW51_RS03505	COG3956	TIGRFAM MazG family protein
JMW51_RS03515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JMW51_RS03535	COG0248	Ppx GppA phosphatase
JMW51_RS03540	COG2208	phosphoserine phosphatase activity
JMW51_RS03550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JMW51_RS03555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JMW51_RS03560	COG0254	rRNA binding
JMW51_RS03565	COG3872	metal-dependent enzyme
JMW51_RS03570	COG2890	protein-(glutamine-N5) methyltransferase activity
JMW51_RS03575	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JMW51_RS03585	COG0009	L-threonylcarbamoyladenylate synthase
JMW51_RS03590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMW51_RS03595	COG0698	ribose 5-phosphate isomerase
JMW51_RS03600	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JMW51_RS03605	COG3608	succinylglutamate desuccinylase aspartoacylase
JMW51_RS03605	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JMW51_RS03630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMW51_RS03635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JMW51_RS03640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMW51_RS03645	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JMW51_RS03650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JMW51_RS03655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JMW51_RS03660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JMW51_RS03665	COG0736	holo-[acyl-carrier-protein] synthase activity
JMW51_RS03670	COG0516	GMP reductase activity
JMW51_RS03670	COG0517	IMP dehydrogenase activity
JMW51_RS03690	COG2337	Toxic component of a toxin-antitoxin (TA) module
JMW51_RS03695	COG3959	Transketolase, thiamine diphosphate binding domain
JMW51_RS03700	COG3958	Transketolase
JMW51_RS03705	COG3949	Membrane
JMW51_RS03715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JMW51_RS03720	COG0793	Belongs to the peptidase S41A family
JMW51_RS03720	COG3409	Peptidoglycan-binding domain 1 protein
JMW51_RS03730	COG2188	Transcriptional regulator
JMW51_RS03740	COG0673	inositol 2-dehydrogenase activity
JMW51_RS03745	COG2222	sugar isomerase
JMW51_RS03750	COG0191	fructose-bisphosphate aldolase activity
JMW51_RS03755	COG3711	transcriptional antiterminator
JMW51_RS03760	COG1363	Peptidase, m42
JMW51_RS03765	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW51_RS03770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS03785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW51_RS03800	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JMW51_RS03810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JMW51_RS03820	COG1492	cobalamin metabolic process
JMW51_RS03825	COG1797	cobyrinic acid a,c-diamide synthase activity
JMW51_RS03835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW51_RS03850	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JMW51_RS03890	COG0181	hydroxymethylbilane synthase activity
JMW51_RS03900	COG0113	porphobilinogen synthase activity
JMW51_RS03905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JMW51_RS03905	COG1648	precorrin-2 dehydrogenase activity
JMW51_RS03925	COG3842	ATPase activity
JMW51_RS03930	COG1175	transmembrane transport
JMW51_RS03940	COG1653	transport
JMW51_RS03950	COG0556	nucleotide-excision repair
JMW51_RS03960	COG0322	excinuclease ABC activity
JMW51_RS03990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMW51_RS03995	COG2116	formate transmembrane transporter activity
JMW51_RS04000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JMW51_RS04010	COG1660	Displays ATPase and GTPase activities
JMW51_RS04025	COG1481	regulation of sporulation
JMW51_RS04035	COG0205	6-phosphofructokinase activity
JMW51_RS04045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JMW51_RS04120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMW51_RS04120	COG0551	DNA topoisomerase type I activity
JMW51_RS04145	COG5290	Psort location Cytoplasmic, score
JMW51_RS04160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMW51_RS04165	COG0348	domain, Protein
JMW51_RS04165	COG3901	Regulator of nitric oxide reductase transcription
JMW51_RS04175	COG1136	(ABC) transporter
JMW51_RS04190	COG5002	protein histidine kinase activity
JMW51_RS04240	COG2199	diguanylate cyclase activity
JMW51_RS04245	COG4555	ABC transporter
JMW51_RS04265	COG0745	RESPONSE REGULATOR receiver
JMW51_RS04270	COG0488	(ABC) transporter
JMW51_RS04285	COG1733	regulation of RNA biosynthetic process
JMW51_RS04290	COG0778	Nitroreductase
JMW51_RS04300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS04315	COG0463	Glycosyl transferase, family 2
JMW51_RS04315	COG0457	Tetratricopeptide repeat
JMW51_RS04365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JMW51_RS04370	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW51_RS04380	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW51_RS04380	COG0493	'glutamate synthase
JMW51_RS04400	COG2946	Replication initiation factor
JMW51_RS04455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JMW51_RS04470	COG0544	peptidyl-prolyl cis-trans isomerase activity
JMW51_RS04475	COG0740	serine-type endopeptidase activity
JMW51_RS04480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JMW51_RS04485	COG2059	Chromate
JMW51_RS04495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JMW51_RS04500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JMW51_RS04505	COG2814	Major facilitator Superfamily
JMW51_RS04520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMW51_RS04525	COG1459	type II secretion system
JMW51_RS04550	COG3012	SEC-C Motif Domain Protein
JMW51_RS04550	COG1405	negative regulation of cell septum assembly
JMW51_RS04565	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JMW51_RS04575	COG0166	Belongs to the GPI family
JMW51_RS04580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMW51_RS04595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMW51_RS04605	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS04605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS04610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS04610	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS04615	COG3715	PTS system
JMW51_RS04620	COG3716	PTS system mannose fructose sorbose family IID component
JMW51_RS04625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JMW51_RS04650	COG1285	pathogenesis
JMW51_RS04655	COG1164	Oligoendopeptidase f
JMW51_RS04660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JMW51_RS04665	COG0745	RESPONSE REGULATOR receiver
JMW51_RS04680	COG0573	inorganic phosphate transmembrane transporter activity
JMW51_RS04685	COG0581	inorganic phosphate transmembrane transporter activity
JMW51_RS04690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JMW51_RS04695	COG0704	Plays a role in the regulation of phosphate uptake
JMW51_RS04710	COG0726	polysaccharide deacetylase
JMW51_RS04715	COG0525	valine-tRNA ligase activity
JMW51_RS04720	COG3279	Response regulator of the LytR AlgR family
JMW51_RS04730	COG0285	dihydrofolate synthase activity
JMW51_RS04755	COG0726	polysaccharide deacetylase
JMW51_RS04760	COG4656	Part of a membrane complex involved in electron transport
JMW51_RS04775	COG5275	peptidyl-tyrosine sulfation
JMW51_RS04775	COG0252	asparaginase activity
JMW51_RS04790	COG5275	peptidyl-tyrosine sulfation
JMW51_RS04790	COG0252	asparaginase activity
JMW51_RS04795	COG5275	peptidyl-tyrosine sulfation
JMW51_RS04795	COG0252	asparaginase activity
JMW51_RS04820	COG2226	methyltransferase
JMW51_RS04830	COG3829	transcription factor binding
JMW51_RS04835	COG3681	Belongs to the UPF0597 family
JMW51_RS04840	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JMW51_RS04850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JMW51_RS04860	COG2171	N-acyltransferase activity
JMW51_RS04865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JMW51_RS04870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW51_RS04875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JMW51_RS04880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW51_RS04885	COG1760	l-serine dehydratase
JMW51_RS04890	COG1473	amidohydrolase
JMW51_RS04900	COG2226	methyltransferase
JMW51_RS04905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JMW51_RS04915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMW51_RS04920	COG1732	Glycine betaine
JMW51_RS04955	COG0534	Mate efflux family protein
JMW51_RS04965	COG0778	Nitroreductase
JMW51_RS04975	COG0706	membrane insertase activity
JMW51_RS04980	COG0745	RESPONSE REGULATOR receiver
JMW51_RS04985	COG2770	Histidine kinase
JMW51_RS04985	COG2205	protein histidine kinase activity
JMW51_RS05010	COG0789	Transcriptional regulator
JMW51_RS05020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMW51_RS05045	COG0577	efflux transmembrane transporter activity
JMW51_RS05050	COG1136	(ABC) transporter
JMW51_RS05055	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS05055	COG2247	cell wall binding repeat
JMW51_RS05075	COG0789	Transcriptional regulator
JMW51_RS05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JMW51_RS05090	COG0251	oxidation-reduction process
JMW51_RS05095	COG3829	transcription factor binding
JMW51_RS05110	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JMW51_RS05115	COG0402	S-adenosylhomocysteine deaminase activity
JMW51_RS05125	COG0167	dihydroorotate dehydrogenase activity
JMW51_RS05135	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW51_RS05140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JMW51_RS05145	COG2390	Transcriptional regulator
JMW51_RS05155	COG0126	phosphoglycerate kinase activity
JMW51_RS05160	COG0149	triose-phosphate isomerase activity
JMW51_RS05165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JMW51_RS05170	COG0148	phosphopyruvate hydratase activity
JMW51_RS05200	COG1881	PFAM PEBP family protein
JMW51_RS05215	COG0557	exoribonuclease II activity
JMW51_RS05245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JMW51_RS05300	COG0693	protein deglycase activity
JMW51_RS05320	COG3711	transcriptional antiterminator
JMW51_RS05325	COG1263	PTS System
JMW51_RS05325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05325	COG2190	(PTS) system
JMW51_RS05330	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS05335	COG1840	ABC-type Fe3 transport system, periplasmic component
JMW51_RS05345	COG3842	ATPase activity
JMW51_RS05350	COG1178	ABC-type Fe3 transport system permease component
JMW51_RS05355	COG0191	fructose-bisphosphate aldolase activity
JMW51_RS05360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05365	COG3711	transcriptional antiterminator
JMW51_RS05370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05380	COG3711	transcriptional antiterminator
JMW51_RS05385	COG1263	PTS System
JMW51_RS05385	COG2190	(PTS) system
JMW51_RS05385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05390	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS05400	COG0640	Transcriptional regulator
JMW51_RS05410	COG1695	Transcriptional regulator
JMW51_RS05415	COG2223	nitrite transmembrane transporter activity
JMW51_RS05425	COG3620	sequence-specific DNA binding
JMW51_RS05430	COG1819	glycosyl
JMW51_RS05455	COG1136	(ABC) transporter
JMW51_RS05465	COG1263	PTS System
JMW51_RS05465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05465	COG2190	(PTS) system
JMW51_RS05470	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS05475	COG0778	Nitroreductase
JMW51_RS05480	COG1959	2 iron, 2 sulfur cluster binding
JMW51_RS05500	COG0205	6-phosphofructokinase activity
JMW51_RS05505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMW51_RS05510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW51_RS05515	COG3711	transcriptional antiterminator
JMW51_RS05515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMW51_RS05525	COG1454	alcohol dehydrogenase
JMW51_RS05530	COG0561	phosphatase activity
JMW51_RS05535	COG2190	(PTS) system
JMW51_RS05540	COG0745	RESPONSE REGULATOR receiver
JMW51_RS05555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JMW51_RS05570	COG1136	(ABC) transporter
JMW51_RS05575	COG1132	(ABC) transporter
JMW51_RS05585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW51_RS05590	COG1263	PTS System
JMW51_RS05590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05595	COG1288	antiporter activity
JMW51_RS05605	COG3711	transcriptional antiterminator
JMW51_RS05610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05610	COG2190	(PTS) system
JMW51_RS05610	COG1263	PTS System
JMW51_RS05615	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS05620	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS05630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JMW51_RS05640	COG0366	Alpha amylase catalytic
JMW51_RS05645	COG2188	Transcriptional regulator
JMW51_RS05650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05650	COG1263	PTS System
JMW51_RS05650	COG2190	(PTS) system
JMW51_RS05655	COG3394	polysaccharide catabolic process
JMW51_RS05675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05680	COG0191	fructose-bisphosphate aldolase activity
JMW51_RS05685	COG0366	Alpha amylase catalytic
JMW51_RS05715	COG3716	PTS system mannose fructose sorbose family IID component
JMW51_RS05720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05730	COG1940	carbohydrate kinase activity
JMW51_RS05735	COG1070	Carbohydrate kinase
JMW51_RS05755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS05755	COG1263	PTS System
JMW51_RS05770	COG2190	(PTS) system
JMW51_RS05780	COG1136	(ABC) transporter
JMW51_RS05795	COG0642	Histidine kinase
JMW51_RS05800	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JMW51_RS05815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS05825	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JMW51_RS05830	COG2971	BadF BadG BcrA BcrD
JMW51_RS05845	COG1737	Transcriptional regulator
JMW51_RS05860	COG2267	carboxylic ester hydrolase activity
JMW51_RS05880	COG0542	response to heat
JMW51_RS05900	COG0384	phenazine biosynthesis protein PhzF
JMW51_RS05910	COG3118	belongs to the thioredoxin family
JMW51_RS05915	COG0492	ferredoxin-NADP+ reductase activity
JMW51_RS05925	COG5002	protein histidine kinase activity
JMW51_RS05945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMW51_RS05965	COG4975	Glucose uptake
JMW51_RS05970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05970	COG3711	transcriptional antiterminator
JMW51_RS05975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS05975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS05990	COG0383	alpha-mannosidase activity
JMW51_RS05995	COG1733	regulation of RNA biosynthetic process
JMW51_RS06000	COG0785	Cytochrome C biogenesis protein
JMW51_RS06005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMW51_RS06015	COG1376	ErfK ybiS ycfS ynhG family protein
JMW51_RS06020	COG1454	alcohol dehydrogenase
JMW51_RS06045	COG0179	Fumarylacetoacetate (FAA) hydrolase
JMW51_RS06050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW51_RS06060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW51_RS06065	COG1120	ATPase activity
JMW51_RS06075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMW51_RS06080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMW51_RS06100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW51_RS06115	COG0745	RESPONSE REGULATOR receiver
JMW51_RS06120	COG2205	protein histidine kinase activity
JMW51_RS06125	COG1968	undecaprenyl-diphosphatase activity
JMW51_RS06130	COG1136	(ABC) transporter
JMW51_RS06135	COG0577	efflux transmembrane transporter activity
JMW51_RS06165	COG1203	CRISPR-associated helicase, Cas3
JMW51_RS06180	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JMW51_RS06200	COG1268	BioY protein
JMW51_RS06210	COG0318	PFAM AMP-dependent synthetase and ligase
JMW51_RS06220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMW51_RS06230	COG1012	belongs to the aldehyde dehydrogenase family
JMW51_RS06230	COG1454	alcohol dehydrogenase
JMW51_RS06235	COG3300	MHYT domain
JMW51_RS06235	COG5001	Diguanylate cyclase
JMW51_RS06260	COG1269	ATP hydrolysis coupled proton transport
JMW51_RS06265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMW51_RS06270	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
JMW51_RS06285	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
JMW51_RS06290	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
JMW51_RS06295	COG1394	ATPase activity, coupled to movement of substances
JMW51_RS06300	COG1840	ABC-type Fe3 transport system, periplasmic component
JMW51_RS06305	COG3842	ATPase activity
JMW51_RS06310	COG1178	ABC-type Fe3 transport system permease component
JMW51_RS06315	COG2188	Transcriptional regulator
JMW51_RS06325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS06325	COG1263	PTS System
JMW51_RS06330	COG0366	Alpha amylase catalytic
JMW51_RS06335	COG2188	Transcriptional regulator
JMW51_RS06345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS06350	COG1486	melibiose metabolic process
JMW51_RS06355	COG3394	polysaccharide catabolic process
JMW51_RS06360	COG1447	Phosphotransferase system cellobiose-specific component IIA
JMW51_RS06375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW51_RS06380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW51_RS06385	COG1120	ATPase activity
JMW51_RS06425	COG0312	modulator of DNA gyrase
JMW51_RS06430	COG0312	modulator of DNA gyrase
JMW51_RS06440	COG2267	carboxylic ester hydrolase activity
JMW51_RS06445	COG3829	transcription factor binding
JMW51_RS06445	COG3290	protein histidine kinase activity
JMW51_RS06465	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
JMW51_RS06470	COG1253	flavin adenine dinucleotide binding
JMW51_RS06475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW51_RS06485	COG0673	inositol 2-dehydrogenase activity
JMW51_RS06495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JMW51_RS06500	COG1696	Membrane protein involved in D-alanine export
JMW51_RS06505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMW51_RS06510	COG1349	DNA-binding transcription factor activity
JMW51_RS06515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW51_RS06515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JMW51_RS06520	COG1664	Polymer-forming cytoskeletal
JMW51_RS06530	COG0789	Transcriptional regulator
JMW51_RS06535	COG1592	Rubrerythrin
JMW51_RS06545	COG0604	alcohol dehydrogenase
JMW51_RS06560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMW51_RS06575	COG3949	Membrane
JMW51_RS06580	COG1473	amidohydrolase
JMW51_RS06585	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JMW51_RS06590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMW51_RS06600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMW51_RS06615	COG0697	spore germination
JMW51_RS06620	COG0436	Aminotransferase
JMW51_RS06655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JMW51_RS06665	COG1132	(ABC) transporter
JMW51_RS06685	COG2084	Dehydrogenase
JMW51_RS06690	COG2610	gluconate transmembrane transporter activity
JMW51_RS06725	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JMW51_RS06730	COG0632	four-way junction helicase activity
JMW51_RS06735	COG2255	four-way junction helicase activity
JMW51_RS06740	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JMW51_RS06750	COG0343	queuine tRNA-ribosyltransferase activity
JMW51_RS06770	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS06770	COG2247	cell wall binding repeat
JMW51_RS06795	COG0653	protein targeting
JMW51_RS06810	COG2247	cell wall binding repeat
JMW51_RS06810	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS06815	COG2246	polysaccharide biosynthetic process
JMW51_RS06825	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS06825	COG2247	cell wall binding repeat
JMW51_RS06835	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS06840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JMW51_RS06845	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS06845	COG2247	cell wall binding repeat
JMW51_RS06850	COG0728	peptidoglycan biosynthetic process
JMW51_RS06855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW51_RS06875	COG1216	Glycosyl transferase, family 2
JMW51_RS06880	COG1215	transferase activity, transferring glycosyl groups
JMW51_RS06880	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMW51_RS06885	COG1215	transferase activity, transferring glycosyl groups
JMW51_RS06895	COG1215	transferase activity, transferring glycosyl groups
JMW51_RS06900	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JMW51_RS06905	COG0438	transferase activity, transferring glycosyl groups
JMW51_RS06915	COG0791	NLP P60 protein
JMW51_RS06920	COG1649	PFAM Uncharacterised BCR, COG1649
JMW51_RS06925	COG1316	TRANSCRIPTIONal
JMW51_RS06930	COG1316	TRANSCRIPTIONal
JMW51_RS06935	COG0561	phosphatase activity
JMW51_RS06945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JMW51_RS06950	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS06975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS07020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JMW51_RS07020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JMW51_RS07025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMW51_RS07030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JMW51_RS07035	COG1490	D-aminoacyl-tRNA deacylase activity
JMW51_RS07040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMW51_RS07045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JMW51_RS07050	COG0124	histidyl-tRNA synthetase
JMW51_RS07055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JMW51_RS07065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JMW51_RS07070	COG0583	DNA-binding transcription factor activity
JMW51_RS07075	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS07075	COG2247	cell wall binding repeat
JMW51_RS07085	COG1757	Na H antiporter
JMW51_RS07090	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW51_RS07120	COG1937	Protein conserved in bacteria
JMW51_RS07140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMW51_RS07145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW51_RS07160	COG0745	RESPONSE REGULATOR receiver
JMW51_RS07165	COG0642	Histidine kinase
JMW51_RS07165	COG5002	protein histidine kinase activity
JMW51_RS07170	COG3069	C4-dicarboxylate transmembrane transporter activity
JMW51_RS07175	COG0726	polysaccharide deacetylase
JMW51_RS07195	COG4509	Sortase family
JMW51_RS07220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JMW51_RS07225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JMW51_RS07230	COG1376	ErfK ybiS ycfS ynhG family protein
JMW51_RS07240	COG0583	DNA-binding transcription factor activity
JMW51_RS07260	COG2271	Major facilitator Superfamily
JMW51_RS07270	COG0402	S-adenosylhomocysteine deaminase activity
JMW51_RS07275	COG2252	PERMEase
JMW51_RS07310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW51_RS07315	COG2502	aspartate--ammonia ligase
JMW51_RS07330	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS07330	COG1388	LysM domain
JMW51_RS07365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW51_RS07375	COG0671	phosphoesterase, PA-phosphatase related
JMW51_RS07380	COG2081	HI0933 family
JMW51_RS07415	COG4869	propanediol catabolic process
JMW51_RS07425	COG2340	Cysteine-rich secretory protein family
JMW51_RS07430	COG2610	gluconate transmembrane transporter activity
JMW51_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
JMW51_RS07445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JMW51_RS07450	COG0183	Belongs to the thiolase family
JMW51_RS07455	COG0583	DNA-binding transcription factor activity
JMW51_RS07460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMW51_RS07465	COG0601	transmembrane transport
JMW51_RS07475	COG0444	Belongs to the ABC transporter superfamily
JMW51_RS07480	COG4608	Belongs to the ABC transporter superfamily
JMW51_RS07485	COG0025	NhaP-type Na H and K H
JMW51_RS07490	COG3711	transcriptional antiterminator
JMW51_RS07495	COG1263	PTS System
JMW51_RS07495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS07495	COG2190	(PTS) system
JMW51_RS07505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMW51_RS07510	COG5001	Diguanylate cyclase
JMW51_RS07510	COG3300	MHYT domain
JMW51_RS07515	COG0012	GTP binding
JMW51_RS07525	COG0612	Peptidase, M16
JMW51_RS07530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JMW51_RS07535	COG0275	rRNA processing
JMW51_RS07545	COG0768	penicillin binding
JMW51_RS07550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JMW51_RS07555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMW51_RS07560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMW51_RS07565	COG0772	Belongs to the SEDS family
JMW51_RS07570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW51_RS07590	COG3856	small basic protein
JMW51_RS07595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JMW51_RS07610	COG1191	sigma factor activity
JMW51_RS07615	COG1191	sigma factor activity
JMW51_RS07620	COG1873	PFAM PRC-barrel domain
JMW51_RS07625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JMW51_RS07635	COG0745	RESPONSE REGULATOR receiver
JMW51_RS07640	COG5002	protein histidine kinase activity
JMW51_RS07665	COG1160	GTP binding
JMW51_RS07670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JMW51_RS07675	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JMW51_RS07695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JMW51_RS07705	COG3830	Belongs to the UPF0237 family
JMW51_RS07725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JMW51_RS07730	COG1799	cell septum assembly
JMW51_RS07740	COG2302	S4 RNA-binding domain
JMW51_RS07750	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JMW51_RS07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW51_RS07770	COG1307	EDD domain protein, DegV family
JMW51_RS07775	COG0006	proline dipeptidase activity
JMW51_RS07780	COG0531	amino acid
JMW51_RS07785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JMW51_RS07810	COG3275	phosphorelay sensor kinase activity
JMW51_RS07815	COG3279	Response regulator of the LytR AlgR family
JMW51_RS07820	COG1966	Carbon starvation protein
JMW51_RS07825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JMW51_RS07835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JMW51_RS07840	COG0564	pseudouridine synthase activity
JMW51_RS07845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JMW51_RS07855	COG0488	(ABC) transporter
JMW51_RS07860	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JMW51_RS07870	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JMW51_RS07875	COG1561	YicC-like family, N-terminal region
JMW51_RS07880	COG0194	GDP metabolic process
JMW51_RS07885	COG1758	RNA polymerase activity
JMW51_RS07890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMW51_RS07895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JMW51_RS07900	COG0242	peptide deformylase activity
JMW51_RS07905	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JMW51_RS07915	COG2738	Putative neutral zinc metallopeptidase
JMW51_RS07920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMW51_RS07920	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMW51_RS07925	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JMW51_RS07935	COG2815	serine threonine protein kinase
JMW51_RS07935	COG0515	serine threonine protein kinase
JMW51_RS07940	COG1028	Short-chain dehydrogenase reductase Sdr
JMW51_RS07945	COG1162	GTPase activity
JMW51_RS07950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMW51_RS07955	COG1564	THIamine pyrophosphokinase
JMW51_RS07975	COG5002	protein histidine kinase activity
JMW51_RS07980	COG0383	alpha-mannosidase activity
JMW51_RS07985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS07990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS07990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS07990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS07995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS07995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS07995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS08000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS08000	COG3711	transcriptional antiterminator
JMW51_RS08005	COG0789	Transcriptional regulator
JMW51_RS08020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JMW51_RS08025	COG1302	Protein conserved in bacteria
JMW51_RS08030	COG1461	Dihydroxyacetone kinase
JMW51_RS08035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JMW51_RS08040	COG0742	ribosomal rna small subunit methyltransferase
JMW51_RS08065	COG0395	ABC-type sugar transport system, permease component
JMW51_RS08085	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JMW51_RS08085	COG4124	Belongs to the glycosyl hydrolase 26 family
JMW51_RS08110	COG1823	symporter activity
JMW51_RS08115	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMW51_RS08120	COG1234	tRNA 3'-trailer cleavage
JMW51_RS08130	COG0737	Belongs to the 5'-nucleotidase family
JMW51_RS08135	COG0745	RESPONSE REGULATOR receiver
JMW51_RS08145	COG0577	efflux transmembrane transporter activity
JMW51_RS08145	COG1136	(ABC) transporter
JMW51_RS08190	COG1309	transcriptional regulator
JMW51_RS08195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JMW51_RS08200	COG2137	regulation of response to DNA damage stimulus
JMW51_RS08205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JMW51_RS08210	COG1713	HD superfamily hydrolase involved in NAD metabolism
JMW51_RS08215	COG0799	negative regulation of ribosome biogenesis
JMW51_RS08220	COG0495	leucyl-tRNA aminoacylation
JMW51_RS08260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JMW51_RS08265	COG0251	oxidation-reduction process
JMW51_RS08270	COG2190	(PTS) system
JMW51_RS08270	COG1263	PTS System
JMW51_RS08270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS08275	COG3711	transcriptional antiterminator
JMW51_RS08280	COG1263	PTS System
JMW51_RS08280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS08300	COG2814	Major facilitator Superfamily
JMW51_RS08305	COG1309	transcriptional regulator
JMW51_RS08310	COG1876	peptidase activity
JMW51_RS08315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW51_RS08320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW51_RS08325	COG0561	phosphatase activity
JMW51_RS08330	COG0165	Argininosuccinate lyase
JMW51_RS08340	COG1686	Belongs to the peptidase S11 family
JMW51_RS08365	COG5002	protein histidine kinase activity
JMW51_RS08370	COG1482	cell wall glycoprotein biosynthetic process
JMW51_RS08375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW51_RS08380	COG3711	transcriptional antiterminator
JMW51_RS08380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS08390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS08395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS08400	COG0006	proline dipeptidase activity
JMW51_RS08405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JMW51_RS08410	COG1396	sequence-specific DNA binding
JMW51_RS08430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JMW51_RS08435	COG3584	3D domain protein
JMW51_RS08435	COG1388	LysM domain
JMW51_RS08445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JMW51_RS08450	COG2333	competence protein COMEC
JMW51_RS08450	COG0658	competence protein
JMW51_RS08465	COG2333	competence protein COMEC
JMW51_RS08465	COG0658	competence protein
JMW51_RS08475	COG0268	Binds directly to 16S ribosomal RNA
JMW51_RS08500	COG0481	GTPase activity
JMW51_RS08505	COG0617	tRNA 3'-terminal CCA addition
JMW51_RS08510	COG0531	amino acid
JMW51_RS08515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JMW51_RS08520	COG1420	regulation of RNA biosynthetic process
JMW51_RS08525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JMW51_RS08530	COG0443	Heat shock 70 kDa protein
JMW51_RS08535	COG0484	heat shock protein binding
JMW51_RS08545	COG0477	Major facilitator Superfamily
JMW51_RS08550	COG2508	Transcriptional regulator
JMW51_RS08555	COG3842	ATPase activity
JMW51_RS08590	COG2264	protein methyltransferase activity
JMW51_RS08595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JMW51_RS08600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW51_RS08605	COG0537	adenosine 5'-monophosphoramidase activity
JMW51_RS08610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JMW51_RS08615	COG1610	YqeY-like protein
JMW51_RS08620	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JMW51_RS08625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMW51_RS08640	COG1702	phosphate starvation-inducible protein PhoH
JMW51_RS08645	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JMW51_RS08650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JMW51_RS08655	COG0295	cytidine deaminase activity
JMW51_RS08660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JMW51_RS08665	COG2239	Acts as a magnesium transporter
JMW51_RS08675	COG1381	Involved in DNA repair and RecF pathway recombination
JMW51_RS08685	COG0752	glycyl-tRNA synthetase alpha subunit
JMW51_RS08690	COG0751	glycine-tRNA ligase activity
JMW51_RS08700	COG1414	Transcriptional regulator
JMW51_RS08710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JMW51_RS08710	COG0674	pyruvate-flavodoxin oxidoreductase activity
JMW51_RS08730	COG0280	phosphate acetyltransferase
JMW51_RS08735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS08740	COG2223	nitrite transmembrane transporter activity
JMW51_RS08745	COG1115	amino acid carrier protein
JMW51_RS08755	COG1288	antiporter activity
JMW51_RS08765	COG2207	Transcriptional regulator
JMW51_RS08775	COG3732	PTS system glucitol sorbitol-specific
JMW51_RS08780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS08780	COG3711	transcriptional antiterminator
JMW51_RS08800	COG0517	IMP dehydrogenase activity
JMW51_RS08805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JMW51_RS08810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JMW51_RS08810	COG0574	Belongs to the PEP-utilizing enzyme family
JMW51_RS08840	COG0551	DNA topoisomerase type I activity
JMW51_RS08840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMW51_RS08850	COG1388	LysM domain
JMW51_RS08850	COG3103	Sh3 type 3 domain protein
JMW51_RS08850	COG0791	NLP P60 protein
JMW51_RS08855	COG3546	catalase activity
JMW51_RS08870	COG0037	tRNA processing
JMW51_RS08890	COG2176	DNA-directed DNA polymerase activity
JMW51_RS08895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JMW51_RS08900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW51_RS08900	COG0072	phenylalanine-tRNA ligase activity
JMW51_RS08960	COG2203	Gaf domain
JMW51_RS08960	COG2199	diguanylate cyclase activity
JMW51_RS08965	COG2199	diguanylate cyclase activity
JMW51_RS08990	COG3426	butyrate kinase activity
JMW51_RS08995	COG2364	Membrane
JMW51_RS09005	COG0628	permease
JMW51_RS09020	COG1966	Carbon starvation protein
JMW51_RS09025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JMW51_RS09035	COG0157	Belongs to the NadC ModD family
JMW51_RS09075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW51_RS09080	COG1116	anion transmembrane transporter activity
JMW51_RS09095	COG0561	phosphatase activity
JMW51_RS09115	COG3118	belongs to the thioredoxin family
JMW51_RS09145	COG0006	proline dipeptidase activity
JMW51_RS09155	COG0583	DNA-binding transcription factor activity
JMW51_RS09160	COG2985	domain, Protein
JMW51_RS09160	COG2985	domain, Protein
JMW51_RS09160	COG0490	domain, Protein
JMW51_RS09160	COG0490	domain, Protein
JMW51_RS09165	COG0427	acetyl-CoA hydrolase
JMW51_RS09170	COG1012	belongs to the aldehyde dehydrogenase family
JMW51_RS09185	COG0427	acetyl-CoA hydrolase
JMW51_RS09190	COG1454	alcohol dehydrogenase
JMW51_RS09200	COG3853	Toxic anion resistance protein (TelA)
JMW51_RS09205	COG0516	GMP reductase activity
JMW51_RS09205	COG0517	IMP dehydrogenase activity
JMW51_RS09215	COG3711	transcriptional antiterminator
JMW51_RS09220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS09225	COG0246	Mannitol dehydrogenase
JMW51_RS09230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMW51_RS09235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMW51_RS09240	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS09240	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS09250	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW51_RS09255	COG3775	system Galactitol-specific IIC component
JMW51_RS09260	COG1063	alcohol dehydrogenase
JMW51_RS09270	COG3959	Transketolase, thiamine diphosphate binding domain
JMW51_RS09275	COG3958	Transketolase
JMW51_RS09280	COG0698	ribose 5-phosphate isomerase
JMW51_RS09285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMW51_RS09290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW51_RS09340	COG3620	sequence-specific DNA binding
JMW51_RS09390	COG5002	protein histidine kinase activity
JMW51_RS09400	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JMW51_RS09405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS09425	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS09425	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS09430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS09430	COG2213	PTS system mannitol-specific
JMW51_RS09435	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW51_RS09440	COG3775	system Galactitol-specific IIC component
JMW51_RS09445	COG1063	alcohol dehydrogenase
JMW51_RS09450	COG0235	Class ii aldolase
JMW51_RS09455	COG0235	Class ii aldolase
JMW51_RS09460	COG1115	amino acid carrier protein
JMW51_RS09480	COG2365	Tyrosine phosphatase family
JMW51_RS09485	COG3711	transcriptional antiterminator
JMW51_RS09485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS09490	COG1105	Belongs to the carbohydrate kinase PfkB family
JMW51_RS09495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMW51_RS09495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS09495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMW51_RS09505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JMW51_RS09505	COG0723	plastoquinol--plastocyanin reductase activity
JMW51_RS09520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMW51_RS09525	COG3104	oligopeptide transport
JMW51_RS09530	COG0006	proline dipeptidase activity
JMW51_RS09535	COG3104	oligopeptide transport
JMW51_RS09540	COG0662	Cupin 2, conserved barrel domain protein
JMW51_RS09570	COG1509	lysine 2,3-aminomutase activity
JMW51_RS09585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMW51_RS09595	COG1404	Belongs to the peptidase S8 family
JMW51_RS09610	COG0017	Asparaginyl-tRNA synthetase
JMW51_RS09615	COG2203	Gaf domain
JMW51_RS09615	COG3706	GGDEF domain
JMW51_RS09615	COG4251	negative regulation of phosphorylation
JMW51_RS09615	COG5001	Diguanylate cyclase
JMW51_RS09630	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
JMW51_RS09635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMW51_RS09640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMW51_RS09700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW51_RS09710	COG0710	3-dehydroquinate dehydratase activity
JMW51_RS09730	COG0288	reversible hydration of carbon dioxide
JMW51_RS09745	COG1132	(ABC) transporter
JMW51_RS09750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMW51_RS09765	COG1012	belongs to the aldehyde dehydrogenase family
JMW51_RS09770	COG0628	permease
JMW51_RS09775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JMW51_RS09780	COG1309	transcriptional regulator
JMW51_RS09795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW51_RS09805	COG0674	pyruvate-flavodoxin oxidoreductase activity
JMW51_RS09805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JMW51_RS09825	COG1528	Iron-storage protein
JMW51_RS09845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW51_RS09865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW51_RS09870	COG1554	hydrolase, family 65, central catalytic
JMW51_RS09875	COG1705	Flagellar rod assembly protein muramidase FlgJ
JMW51_RS09900	COG0596	Alpha beta hydrolase
JMW51_RS09905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JMW51_RS09910	COG0243	molybdopterin cofactor binding
JMW51_RS09915	COG0437	4 iron, 4 sulfur cluster binding
JMW51_RS09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMW51_RS09945	COG1126	abc transporter atp-binding protein
JMW51_RS09950	COG1301	dicarboxylic acid transport
JMW51_RS09970	COG1151	hydroxylamine reductase activity
JMW51_RS09980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMW51_RS09980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMW51_RS09995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMW51_RS10035	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JMW51_RS10040	COG1160	GTP binding
JMW51_RS10050	COG1363	Peptidase, m42
JMW51_RS10070	COG2720	vancomycin resistance protein
JMW51_RS10085	COG1193	negative regulation of DNA recombination
JMW51_RS10105	COG1686	Belongs to the peptidase S11 family
JMW51_RS10110	COG0052	Belongs to the universal ribosomal protein uS2 family
JMW51_RS10115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JMW51_RS10120	COG0528	UMP kinase activity
JMW51_RS10125	COG0233	cytoplasmic translational termination
JMW51_RS10140	COG4589	Belongs to the CDS family
JMW51_RS10195	COG1518	maintenance of DNA repeat elements
JMW51_RS10200	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JMW51_RS10210	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JMW51_RS10215	COG0750	zinc metalloprotease
JMW51_RS10220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JMW51_RS10240	COG1247	-acetyltransferase
JMW51_RS10285	COG0492	ferredoxin-NADP+ reductase activity
JMW51_RS10290	COG1217	gtp-binding protein TYPA
JMW51_RS10305	COG2217	Heavy metal translocating P-type atpase
JMW51_RS10310	COG0745	RESPONSE REGULATOR receiver
JMW51_RS10315	COG5002	protein histidine kinase activity
JMW51_RS10325	COG1349	DNA-binding transcription factor activity
JMW51_RS10330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMW51_RS10340	COG0534	Mate efflux family protein
JMW51_RS10345	COG2252	PERMEase
JMW51_RS10355	COG1131	(ABC) transporter
JMW51_RS10390	COG2080	2 iron, 2 sulfur cluster binding
JMW51_RS10390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW51_RS10400	COG4708	membrane
JMW51_RS10415	COG1401	restriction endodeoxyribonuclease activity
JMW51_RS10425	COG3829	transcription factor binding
JMW51_RS10450	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW51_RS10475	COG0402	S-adenosylhomocysteine deaminase activity
JMW51_RS10495	COG0402	S-adenosylhomocysteine deaminase activity
JMW51_RS10500	COG0167	dihydroorotate dehydrogenase activity
JMW51_RS10510	COG2233	PERMEase
JMW51_RS10520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JMW51_RS10520	COG2080	2 iron, 2 sulfur cluster binding
JMW51_RS10530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMW51_RS10545	COG0488	(ABC) transporter
JMW51_RS10555	COG0582	viral genome integration into host DNA
JMW51_RS10585	COG1597	lipid kinase activity
JMW51_RS10590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMW51_RS10615	COG0527	aspartate kinase activity
JMW51_RS10620	COG0019	diaminopimelate decarboxylase activity
JMW51_RS10630	COG0628	permease
JMW51_RS10635	COG1187	pseudouridine synthase activity
JMW51_RS10640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JMW51_RS10645	COG1737	Transcriptional regulator
JMW51_RS10665	COG3655	Transcriptional regulator
JMW51_RS10680	COG1309	transcriptional regulator
JMW51_RS10690	COG0456	acetyltransferase
JMW51_RS10700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JMW51_RS10705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JMW51_RS10710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JMW51_RS10715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JMW51_RS10725	COG1794	racemase activity, acting on amino acids and derivatives
JMW51_RS10750	COG1725	Transcriptional regulator
JMW51_RS10770	COG2814	Major facilitator Superfamily
JMW51_RS10775	COG2207	Transcriptional regulator
JMW51_RS10805	COG0129	dihydroxy-acid dehydratase activity
JMW51_RS10820	COG1404	Belongs to the peptidase S8 family
JMW51_RS10835	COG0789	Transcriptional regulator
JMW51_RS10840	COG1321	iron dependent repressor
JMW51_RS10845	COG2207	Transcriptional regulator
JMW51_RS10850	COG0730	response to heat
JMW51_RS10970	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS10970	COG2247	cell wall binding repeat
JMW51_RS10975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW51_RS10985	COG0494	nUDIX hydrolase
JMW51_RS10990	COG0384	phenazine biosynthesis protein PhzF
JMW51_RS10995	COG1733	regulation of RNA biosynthetic process
JMW51_RS11020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW51_RS11025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JMW51_RS11030	COG1116	anion transmembrane transporter activity
JMW51_RS11035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMW51_RS11040	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JMW51_RS11045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JMW51_RS11050	COG1923	regulation of RNA biosynthetic process
JMW51_RS11055	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JMW51_RS11060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMW51_RS11075	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
JMW51_RS11080	COG1811	Na channel or pump
JMW51_RS11110	COG2264	protein methyltransferase activity
JMW51_RS11120	COG1136	(ABC) transporter
JMW51_RS11120	COG0577	efflux transmembrane transporter activity
JMW51_RS11125	COG5002	protein histidine kinase activity
JMW51_RS11130	COG0745	RESPONSE REGULATOR receiver
JMW51_RS11140	COG0745	RESPONSE REGULATOR receiver
JMW51_RS11145	COG2205	protein histidine kinase activity
JMW51_RS11150	COG1136	(ABC) transporter
JMW51_RS11150	COG0577	efflux transmembrane transporter activity
JMW51_RS11170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMW51_RS11175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW51_RS11180	COG2205	protein histidine kinase activity
JMW51_RS11190	COG1136	(ABC) transporter
JMW51_RS11200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JMW51_RS11220	COG0511	ligase activity, forming carbon-carbon bonds
JMW51_RS11225	COG0439	Biotin carboxylase
JMW51_RS11230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JMW51_RS11235	COG0825	malonyl-CoA metabolic process
JMW51_RS11240	COG2359	stage V sporulation protein S
JMW51_RS11255	COG4974	Belongs to the 'phage' integrase family
JMW51_RS11260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JMW51_RS11280	COG1116	anion transmembrane transporter activity
JMW51_RS11300	COG4766	ethanolamine catabolic process
JMW51_RS11305	COG3192	ethanolamine utilization protein
JMW51_RS11315	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
JMW51_RS11325	COG4869	propanediol catabolic process
JMW51_RS11340	COG1012	belongs to the aldehyde dehydrogenase family
JMW51_RS11340	COG1454	alcohol dehydrogenase
JMW51_RS11355	COG4302	ethanolamine ammonia-lyase activity
JMW51_RS11360	COG4303	Ethanolamine ammonia lyase large subunit
JMW51_RS11365	COG4819	ethanolamine utilization protein
JMW51_RS11405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW51_RS11415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMW51_RS11450	COG2131	deaminase
JMW51_RS11480	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
JMW51_RS11485	COG2226	methyltransferase
JMW51_RS11490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JMW51_RS11510	COG5001	Diguanylate cyclase
JMW51_RS11510	COG5002	protein histidine kinase activity
JMW51_RS11520	COG0287	Prephenate dehydrogenase
JMW51_RS11530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JMW51_RS11535	COG1605	Chorismate mutase
JMW51_RS11535	COG0077	Prephenate dehydratase
JMW51_RS11540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JMW51_RS11545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JMW51_RS11550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JMW51_RS11555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JMW51_RS11560	COG0598	Magnesium transport protein CorA
JMW51_RS11570	COG2205	protein histidine kinase activity
JMW51_RS11575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMW51_RS11580	COG1846	Transcriptional regulator
JMW51_RS11585	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JMW51_RS11600	COG3022	response to hydroperoxide
JMW51_RS11605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JMW51_RS11620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JMW51_RS11625	COG0204	Acyl-transferase
JMW51_RS11630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JMW51_RS11635	COG2081	HI0933 family
JMW51_RS11640	COG0406	alpha-ribazole phosphatase activity
JMW51_RS11670	COG2814	Major facilitator Superfamily
JMW51_RS11680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMW51_RS11685	COG1621	beta-fructofuranosidase activity
JMW51_RS11695	COG1609	Transcriptional regulator
JMW51_RS11705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW51_RS11720	COG0583	DNA-binding transcription factor activity
JMW51_RS11725	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMW51_RS11750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JMW51_RS11765	COG2323	membrane
JMW51_RS11775	COG0789	Transcriptional regulator
JMW51_RS11785	COG0137	argininosuccinate synthase activity
JMW51_RS11795	COG5002	protein histidine kinase activity
JMW51_RS11795	COG3850	Histidine kinase
JMW51_RS11810	COG0116	Belongs to the methyltransferase superfamily
JMW51_RS11815	COG1606	tRNA processing
JMW51_RS11825	COG1393	Belongs to the ArsC family
JMW51_RS11835	COG0765	amino acid transport
JMW51_RS11840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMW51_RS11885	COG0494	nUDIX hydrolase
JMW51_RS11895	COG3326	Membrane
JMW51_RS11930	COG0242	peptide deformylase activity
JMW51_RS11955	COG1309	transcriptional regulator
JMW51_RS11970	COG1924	4 iron, 4 sulfur cluster binding
JMW51_RS11975	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
JMW51_RS12005	COG0786	glutamate:sodium symporter activity
JMW51_RS12040	COG2204	response regulator
JMW51_RS12045	COG5002	protein histidine kinase activity
JMW51_RS12050	COG2610	gluconate transmembrane transporter activity
JMW51_RS12055	COG1917	Cupin 2, conserved barrel domain protein
JMW51_RS12055	COG1396	sequence-specific DNA binding
JMW51_RS12060	COG1011	Hydrolase
JMW51_RS12070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JMW51_RS12075	COG5012	cobalamin binding
JMW51_RS12130	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
JMW51_RS12135	COG2207	Transcriptional regulator
JMW51_RS12140	COG1283	sodium-dependent phosphate transmembrane transporter activity
JMW51_RS12215	COG0315	cyclic pyranopterin monophosphate synthase activity
JMW51_RS12225	COG0521	Mo-molybdopterin cofactor biosynthetic process
JMW51_RS12230	COG0393	Putative heavy-metal-binding
JMW51_RS12250	COG1288	antiporter activity
JMW51_RS12265	COG2022	thiamine diphosphate biosynthetic process
JMW51_RS12280	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JMW51_RS12285	COG0514	ATP-dependent DNA helicase (RecQ)
JMW51_RS12300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMW51_RS12300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMW51_RS12315	COG1115	amino acid carrier protein
JMW51_RS12345	COG3118	belongs to the thioredoxin family
JMW51_RS12350	COG5002	protein histidine kinase activity
JMW51_RS12355	COG0745	RESPONSE REGULATOR receiver
JMW51_RS12390	COG1309	transcriptional regulator
JMW51_RS12415	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JMW51_RS12420	COG1733	regulation of RNA biosynthetic process
JMW51_RS12435	COG2205	protein histidine kinase activity
JMW51_RS12440	COG0745	RESPONSE REGULATOR receiver
JMW51_RS12450	COG1131	(ABC) transporter
JMW51_RS12465	COG0584	glycerophosphoryl diester phosphodiesterase
JMW51_RS12475	COG1396	sequence-specific DNA binding
JMW51_RS12505	COG3123	guanosine phosphorylase activity
JMW51_RS12510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JMW51_RS12515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JMW51_RS12520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JMW51_RS12530	COG1757	Na H antiporter
JMW51_RS12535	COG0095	Lipoate-protein ligase
JMW51_RS12550	COG3706	GGDEF domain
JMW51_RS12550	COG2203	Gaf domain
JMW51_RS12550	COG5001	Diguanylate cyclase
JMW51_RS12550	COG4251	negative regulation of phosphorylation
JMW51_RS12555	COG4607	ABC-type enterochelin transport system periplasmic component
JMW51_RS12560	COG4604	ABC transporter, ATP-binding protein
JMW51_RS12565	COG4605	iron ion homeostasis
JMW51_RS12570	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMW51_RS12580	COG5505	Protein of unknown function (DUF819)
JMW51_RS12610	COG3853	Toxic anion resistance protein (TelA)
JMW51_RS12625	COG2310	stress, protein
JMW51_RS12640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMW51_RS12645	COG0367	asparagine synthase
JMW51_RS12665	COG0426	domain, Protein
JMW51_RS12675	COG0668	transmembrane transport
JMW51_RS12690	COG1131	(ABC) transporter
JMW51_RS12695	COG1725	Transcriptional regulator
JMW51_RS12700	COG5001	Diguanylate cyclase
JMW51_RS12700	COG3300	MHYT domain
JMW51_RS12705	COG1668	transmembrane transport
JMW51_RS12710	COG4555	ABC transporter
JMW51_RS12720	COG0402	S-adenosylhomocysteine deaminase activity
JMW51_RS12745	COG1131	(ABC) transporter
JMW51_RS12750	COG1725	Transcriptional regulator
JMW51_RS12770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS12775	COG0352	thiamine-phosphate diphosphorylase activity
JMW51_RS12780	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JMW51_RS12785	COG0351	phosphomethylpyrimidine kinase
JMW51_RS12800	COG0024	Methionine aminopeptidase
JMW51_RS12810	COG1045	serine acetyltransferase
JMW51_RS12815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JMW51_RS12820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JMW51_RS12825	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JMW51_RS12830	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JMW51_RS12840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW51_RS12860	COG0596	Alpha beta hydrolase
JMW51_RS12865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JMW51_RS12875	COG0460	homoserine dehydrogenase
JMW51_RS12880	COG5002	protein histidine kinase activity
JMW51_RS12885	COG1295	ribonuclease BN
JMW51_RS12890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMW51_RS12900	COG1388	LysM domain
JMW51_RS12900	COG3584	3D domain protein
JMW51_RS12920	COG1136	(ABC) transporter
JMW51_RS12925	COG2267	carboxylic ester hydrolase activity
JMW51_RS12935	COG1331	Highly conserved protein containing a thioredoxin domain
JMW51_RS12940	COG3546	catalase activity
JMW51_RS12945	COG0028	Belongs to the TPP enzyme family
JMW51_RS12950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JMW51_RS12965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JMW51_RS12980	COG1595	DNA-templated transcription, initiation
JMW51_RS12995	COG0531	amino acid
JMW51_RS13000	COG0140	phosphoribosyl-ATP diphosphatase activity
JMW51_RS13000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JMW51_RS13005	COG0107	imidazoleglycerol-phosphate synthase activity
JMW51_RS13010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JMW51_RS13015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JMW51_RS13020	COG0131	Imidazoleglycerol-phosphate dehydratase
JMW51_RS13025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMW51_RS13030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JMW51_RS13035	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JMW51_RS13075	COG0577	efflux transmembrane transporter activity
JMW51_RS13080	COG1136	(ABC) transporter
JMW51_RS13090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW51_RS13090	COG0493	'glutamate synthase
JMW51_RS13105	COG0405	Gamma-glutamyltransferase
JMW51_RS13110	COG0577	efflux transmembrane transporter activity
JMW51_RS13115	COG1136	(ABC) transporter
JMW51_RS13120	COG0745	RESPONSE REGULATOR receiver
JMW51_RS13125	COG2205	protein histidine kinase activity
JMW51_RS13135	COG0577	efflux transmembrane transporter activity
JMW51_RS13135	COG1136	(ABC) transporter
JMW51_RS13140	COG0577	efflux transmembrane transporter activity
JMW51_RS13145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JMW51_RS13150	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
JMW51_RS13155	COG1592	Rubrerythrin
JMW51_RS13155	COG1773	rubredoxin
JMW51_RS13165	COG0726	polysaccharide deacetylase
JMW51_RS13170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JMW51_RS13190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JMW51_RS13195	COG4978	Transcriptional regulator
JMW51_RS13195	COG0789	Transcriptional regulator
JMW51_RS13200	COG5001	Diguanylate cyclase
JMW51_RS13210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JMW51_RS13215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JMW51_RS13240	COG3901	Regulator of nitric oxide reductase transcription
JMW51_RS13240	COG0348	domain, Protein
JMW51_RS13250	COG0534	Mate efflux family protein
JMW51_RS13260	COG1131	(ABC) transporter
JMW51_RS13270	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JMW51_RS13285	COG0701	Predicted permease
JMW51_RS13290	COG0523	cobalamin synthesis protein
JMW51_RS13295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMW51_RS13300	COG1121	(ABC) transporter
JMW51_RS13305	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMW51_RS13325	COG4086	secreted protein
JMW51_RS13330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMW51_RS13335	COG1396	sequence-specific DNA binding
JMW51_RS13340	COG2094	Belongs to the DNA glycosylase MPG family
JMW51_RS13345	COG5002	protein histidine kinase activity
JMW51_RS13350	COG1464	Belongs to the NlpA lipoprotein family
JMW51_RS13355	COG2011	ABC-type metal ion transport system permease component
JMW51_RS13360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JMW51_RS13395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JMW51_RS13430	COG0412	Dienelactone hydrolase
JMW51_RS13435	COG1592	Rubrerythrin
JMW51_RS13435	COG1773	rubredoxin
JMW51_RS13440	COG1132	(ABC) transporter
JMW51_RS13445	COG1132	(ABC) transporter
JMW51_RS13475	COG0577	efflux transmembrane transporter activity
JMW51_RS13475	COG1136	(ABC) transporter
JMW51_RS13480	COG5002	protein histidine kinase activity
JMW51_RS13480	COG3850	Histidine kinase
JMW51_RS13485	COG0745	RESPONSE REGULATOR receiver
JMW51_RS13495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS13515	COG0655	NAD(P)H dehydrogenase (quinone) activity
JMW51_RS13520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JMW51_RS13525	COG2384	SAM-dependent methyltransferase
JMW51_RS13530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JMW51_RS13535	COG0358	DNA primase activity
JMW51_RS13540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JMW51_RS13545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JMW51_RS13550	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JMW51_RS13555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JMW51_RS13560	COG0302	gtp cyclohydrolase
JMW51_RS13570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JMW51_RS13575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JMW51_RS13580	COG0512	Glutamine amidotransferase of anthranilate synthase
JMW51_RS13585	COG0726	polysaccharide deacetylase
JMW51_RS13590	COG2340	Cysteine-rich secretory protein family
JMW51_RS13600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMW51_RS13605	COG1346	cytolysis
JMW51_RS13620	COG3829	transcription factor binding
JMW51_RS13625	COG2720	vancomycin resistance protein
JMW51_RS13640	COG0450	alkyl hydroperoxide reductase
JMW51_RS13655	COG0726	polysaccharide deacetylase
JMW51_RS13665	COG1285	pathogenesis
JMW51_RS13675	COG4978	Transcriptional regulator
JMW51_RS13675	COG0789	Transcriptional regulator
JMW51_RS13685	COG2199	diguanylate cyclase activity
JMW51_RS13685	COG2203	Gaf domain
JMW51_RS13690	COG3447	MASE1 domain protein
JMW51_RS13690	COG5001	Diguanylate cyclase
JMW51_RS13690	COG5002	protein histidine kinase activity
JMW51_RS13695	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JMW51_RS13720	COG1242	4 iron, 4 sulfur cluster binding
JMW51_RS13730	COG3829	transcription factor binding
JMW51_RS13745	COG1058	Belongs to the CinA family
JMW51_RS13745	COG1546	Belongs to the CinA family
JMW51_RS13750	COG1181	Belongs to the D-alanine--D-alanine ligase family
JMW51_RS13755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS13795	COG0584	glycerophosphoryl diester phosphodiesterase
JMW51_RS13810	COG1619	proteins homologs of microcin C7 resistance protein MccF
JMW51_RS13815	COG1473	amidohydrolase
JMW51_RS13860	COG4948	Mandelate Racemase Muconate Lactonizing
JMW51_RS13865	COG1396	sequence-specific DNA binding
JMW51_RS13870	COG1984	allophanate hydrolase subunit 2
JMW51_RS13875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JMW51_RS13880	COG1914	H( )-stimulated, divalent metal cation uptake system
JMW51_RS13885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JMW51_RS13890	COG3273	potassium ion transport
JMW51_RS13890	COG0471	metal ion transport
JMW51_RS13895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JMW51_RS13905	COG2814	Major facilitator Superfamily
JMW51_RS13910	COG1396	sequence-specific DNA binding
JMW51_RS13925	COG1396	sequence-specific DNA binding
JMW51_RS13955	COG3778	Protein conserved in bacteria
JMW51_RS13960	COG3299	homolog of phage Mu protein gp47
JMW51_RS14030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMW51_RS14040	COG1278	Cold shock
JMW51_RS14070	COG1131	(ABC) transporter
JMW51_RS14095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMW51_RS14110	COG0708	Exodeoxyribonuclease III
JMW51_RS14120	COG0436	Aminotransferase
JMW51_RS14130	COG0114	fumarate hydratase activity
JMW51_RS14140	COG1968	undecaprenyl-diphosphatase activity
JMW51_RS14165	COG5001	Diguanylate cyclase
JMW51_RS14170	COG1418	mRNA catabolic process
JMW51_RS14175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JMW51_RS14185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMW51_RS14190	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
JMW51_RS14200	COG0740	serine-type endopeptidase activity
JMW51_RS14205	COG0527	aspartate kinase activity
JMW51_RS14210	COG1873	PFAM PRC-barrel domain
JMW51_RS14215	COG0612	Peptidase, M16
JMW51_RS14220	COG0726	polysaccharide deacetylase
JMW51_RS14225	COG1185	polyribonucleotide nucleotidyltransferase activity
JMW51_RS14230	COG1307	EDD domain protein, DegV family
JMW51_RS14235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JMW51_RS14240	COG0196	riboflavin kinase activity
JMW51_RS14245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JMW51_RS14250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JMW51_RS14260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JMW51_RS14270	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JMW51_RS14275	COG0195	Participates in both transcription termination and antitermination
JMW51_RS14280	COG0779	Required for maturation of 30S ribosomal subunits
JMW51_RS14335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JMW51_RS14345	COG1994	Peptidase M50
JMW51_RS14350	COG2207	Transcriptional regulator
JMW51_RS14350	COG1917	Cupin 2, conserved barrel domain protein
JMW51_RS14360	COG1686	Belongs to the peptidase S11 family
JMW51_RS14370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMW51_RS14380	COG0735	belongs to the Fur family
JMW51_RS14385	COG3906	Belongs to the UPF0473 family
JMW51_RS14390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JMW51_RS14400	COG4472	Bacterial protein of unknown function (DUF965)
JMW51_RS14405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMW51_RS14410	COG0482	sulfurtransferase activity
JMW51_RS14415	COG0822	iron-sulfur transferase activity
JMW51_RS14425	COG1959	2 iron, 2 sulfur cluster binding
JMW51_RS14435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JMW51_RS14445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMW51_RS14450	COG0758	DNA mediated transformation
JMW51_RS14455	COG0606	chelatase, subunit chli
JMW51_RS14460	COG0792	nuclease activity
JMW51_RS14465	COG4585	Histidine kinase
JMW51_RS14470	COG2197	response regulator
JMW51_RS14475	COG1131	(ABC) transporter
JMW51_RS14505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMW51_RS14520	COG1114	Component of the transport system for branched-chain amino acids
JMW51_RS14530	COG0335	large ribosomal subunit rRNA binding
JMW51_RS14535	COG0336	Belongs to the RNA methyltransferase TrmD family
JMW51_RS14540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JMW51_RS14550	COG0228	four-way junction DNA binding
JMW51_RS14555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JMW51_RS14565	COG0552	protein localization to endoplasmic reticulum
JMW51_RS14570	COG1196	nuclear chromosome segregation
JMW51_RS14580	COG0571	ribonuclease III activity
JMW51_RS14590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JMW51_RS14685	COG0768	penicillin binding
JMW51_RS14690	COG0826	peptidase U32
JMW51_RS14695	COG4122	O-methyltransferase activity
JMW51_RS14700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JMW51_RS14715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JMW51_RS14720	COG4974	Belongs to the 'phage' integrase family
JMW51_RS14730	COG0494	nUDIX hydrolase
JMW51_RS14765	COG0750	zinc metalloprotease
JMW51_RS14770	COG0456	acetyltransferase
JMW51_RS14775	COG0456	acetyltransferase
JMW51_RS14785	COG0497	DNA recombination
JMW51_RS14790	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JMW51_RS14795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JMW51_RS14800	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JMW51_RS14810	COG1722	exodeoxyribonuclease VII activity
JMW51_RS14815	COG1570	exodeoxyribonuclease VII activity
JMW51_RS14820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMW51_RS14825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMW51_RS14830	COG1302	Protein conserved in bacteria
JMW51_RS14870	COG3854	ATPases associated with a variety of cellular activities
JMW51_RS14875	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JMW51_RS14890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JMW51_RS14905	COG3706	GGDEF domain
JMW51_RS14910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JMW51_RS14915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMW51_RS14920	COG1028	Short-chain dehydrogenase reductase Sdr
JMW51_RS14925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JMW51_RS14935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMW51_RS14940	COG0416	fatty acid biosynthetic process
JMW51_RS14950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JMW51_RS14960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JMW51_RS14965	COG1323	Belongs to the UPF0348 family
JMW51_RS14970	COG0277	FAD linked oxidase domain protein
JMW51_RS14975	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW51_RS14980	COG2086	electron transfer activity
JMW51_RS14985	COG3875	lactate racemase activity
JMW51_RS14990	COG2186	Transcriptional regulator
JMW51_RS14995	COG3314	Sporulation integral membrane protein YlbJ
JMW51_RS15005	COG0460	homoserine dehydrogenase
JMW51_RS15015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JMW51_RS15020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JMW51_RS15030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JMW51_RS15035	COG1530	ribonuclease E activity
JMW51_RS15050	COG0426	domain, Protein
JMW51_RS15065	COG1695	Transcriptional regulator
JMW51_RS15070	COG1803	Methylglyoxal synthase
JMW51_RS15075	COG0772	Belongs to the SEDS family
JMW51_RS15080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JMW51_RS15085	COG2894	cell division
JMW51_RS15090	COG0850	regulation of cytokinetic process
JMW51_RS15110	COG1077	Cell shape determining protein MreB Mrl
JMW51_RS15115	COG2003	Belongs to the UPF0758 family
JMW51_RS15120	COG0424	maF-like protein
JMW51_RS15125	COG2878	Part of a membrane complex involved in electron transport
JMW51_RS15125	COG1245	4Fe-4S binding domain
JMW51_RS15130	COG4657	Part of a membrane complex involved in electron transport
JMW51_RS15135	COG4660	Part of a membrane complex involved in electron transport
JMW51_RS15140	COG4659	FMN binding
JMW51_RS15145	COG4658	electron transport chain
JMW51_RS15150	COG4656	Part of a membrane complex involved in electron transport
JMW51_RS15160	COG0791	NLP P60 protein
JMW51_RS15165	COG0346	lactoylglutathione lyase activity
JMW51_RS15190	COG0237	dephospho-CoA kinase activity
JMW51_RS15195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMW51_RS15195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMW51_RS15230	COG3708	Transcriptional regulator
JMW51_RS15230	COG2207	Transcriptional regulator
JMW51_RS15255	COG1396	sequence-specific DNA binding
JMW51_RS15260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMW51_RS15265	COG1882	Formate acetyltransferase
JMW51_RS15280	COG3279	Response regulator of the LytR AlgR family
JMW51_RS15295	COG1473	amidohydrolase
JMW51_RS15305	COG1132	(ABC) transporter
JMW51_RS15310	COG3414	Phosphotransferase system galactitol-specific IIB component
JMW51_RS15330	COG0583	DNA-binding transcription factor activity
JMW51_RS15335	COG3716	PTS system mannose fructose sorbose family IID component
JMW51_RS15340	COG3715	PTS system
JMW51_RS15360	COG2188	Transcriptional regulator
JMW51_RS15365	COG1362	aminopeptidase activity
JMW51_RS15370	COG4224	UPF0291 protein
JMW51_RS15375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS15380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW51_RS15435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMW51_RS15445	COG0564	pseudouridine synthase activity
JMW51_RS15450	COG0183	Belongs to the thiolase family
JMW51_RS15465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW51_RS15470	COG2086	electron transfer activity
JMW51_RS15475	COG1960	acyl-CoA dehydrogenase activity
JMW51_RS15480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMW51_RS15495	COG1131	(ABC) transporter
JMW51_RS15500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JMW51_RS15505	COG0622	Phosphoesterase
JMW51_RS15515	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW51_RS15525	COG4536	flavin adenine dinucleotide binding
JMW51_RS15530	COG0419	ATPase involved in DNA repair
JMW51_RS15535	COG0420	3'-5' exonuclease activity
JMW51_RS15540	COG1074	ATP-dependent DNA helicase activity
JMW51_RS15545	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JMW51_RS15555	COG1074	ATP-dependent DNA helicase activity
JMW51_RS15565	COG2247	cell wall binding repeat
JMW51_RS15565	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS15570	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS15600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JMW51_RS15615	COG1215	transferase activity, transferring glycosyl groups
JMW51_RS15620	COG5298	Protein conserved in bacteria
JMW51_RS15630	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JMW51_RS15635	COG1177	transmembrane transport
JMW51_RS15640	COG1176	ABC-type spermidine putrescine transport system, permease component I
JMW51_RS15645	COG3842	ATPase activity
JMW51_RS15655	COG2364	Membrane
JMW51_RS15675	COG1132	(ABC) transporter
JMW51_RS15685	COG4978	Transcriptional regulator
JMW51_RS15685	COG0789	Transcriptional regulator
JMW51_RS15695	COG5001	Diguanylate cyclase
JMW51_RS15700	COG5002	protein histidine kinase activity
JMW51_RS15715	COG0363	glucosamine-6-phosphate deaminase activity
JMW51_RS15720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JMW51_RS15740	COG0577	efflux transmembrane transporter activity
JMW51_RS15740	COG1136	(ABC) transporter
JMW51_RS15745	COG5002	protein histidine kinase activity
JMW51_RS15750	COG0745	RESPONSE REGULATOR receiver
JMW51_RS15765	COG0281	malic enzyme
JMW51_RS15775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JMW51_RS15780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMW51_RS15805	COG5001	Diguanylate cyclase
JMW51_RS15805	COG3447	MASE1 domain protein
JMW51_RS15805	COG5002	protein histidine kinase activity
JMW51_RS15815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMW51_RS15830	COG0473	3-isopropylmalate dehydrogenase activity
JMW51_RS15835	COG0066	3-isopropylmalate dehydratase activity
JMW51_RS15840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JMW51_RS15845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JMW51_RS15855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW51_RS15860	COG0539	negative regulation of cytoplasmic translation
JMW51_RS15860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JMW51_RS15865	COG0534	Mate efflux family protein
JMW51_RS15895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMW51_RS15900	COG1174	glycine betaine transport
JMW51_RS15910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMW51_RS15915	COG4868	Belongs to the UPF0371 family
JMW51_RS15950	COG0010	Belongs to the arginase family
JMW51_RS15955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JMW51_RS15960	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JMW51_RS15965	COG1982	Orn Lys Arg decarboxylase major
JMW51_RS15970	COG1802	Transcriptional regulator
JMW51_RS15980	COG0058	SHG alpha-glucan phosphorylase activity
JMW51_RS15985	COG0297	glycogen (starch) synthase activity
JMW51_RS15990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JMW51_RS15995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JMW51_RS16010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JMW51_RS16010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JMW51_RS16015	COG4120	Belongs to the binding-protein-dependent transport system permease family
JMW51_RS16025	COG2984	ABC transporter substrate binding protein
JMW51_RS16030	COG4120	Belongs to the binding-protein-dependent transport system permease family
JMW51_RS16045	COG0110	maltose O-acetyltransferase activity
JMW51_RS16050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JMW51_RS16055	COG4149	molybdate abc transporter
JMW51_RS16060	COG0725	ABC transporter, periplasmic molybdate-binding protein
JMW51_RS16065	COG1910	domain protein
JMW51_RS16075	COG1073	alpha beta
JMW51_RS16085	COG1486	melibiose metabolic process
JMW51_RS16095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMW51_RS16110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS16110	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS16115	COG4608	Belongs to the ABC transporter superfamily
JMW51_RS16120	COG0444	Belongs to the ABC transporter superfamily
JMW51_RS16130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMW51_RS16135	COG0601	transmembrane transport
JMW51_RS16150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JMW51_RS16190	COG0297	glycogen (starch) synthase activity
JMW51_RS16190	COG0438	transferase activity, transferring glycosyl groups
JMW51_RS16200	COG0138	bifunctional purine biosynthesis protein purh
JMW51_RS16205	COG0179	Fumarylacetoacetate (FAA) hydrolase
JMW51_RS16230	COG1846	Transcriptional regulator
JMW51_RS16235	COG0473	3-isopropylmalate dehydrogenase activity
JMW51_RS16245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JMW51_RS16285	COG0069	glutamate synthase activity
JMW51_RS16290	COG2033	superoxide reductase activity
JMW51_RS16300	COG1592	Rubrerythrin
JMW51_RS16320	COG5002	protein histidine kinase activity
JMW51_RS16325	COG0745	RESPONSE REGULATOR receiver
JMW51_RS16335	COG2723	6-phospho-beta-galactosidase activity
JMW51_RS16340	COG1263	PTS System
JMW51_RS16340	COG2190	(PTS) system
JMW51_RS16340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS16345	COG2814	Major facilitator Superfamily
JMW51_RS16350	COG2186	Transcriptional regulator
JMW51_RS16390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JMW51_RS16395	COG2086	electron transfer activity
JMW51_RS16410	COG2610	gluconate transmembrane transporter activity
JMW51_RS16415	COG1024	Enoyl-CoA hydratase
JMW51_RS16420	COG0217	transcriptional regulatory protein
JMW51_RS16425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JMW51_RS16430	COG0730	response to heat
JMW51_RS16440	COG1739	Uncharacterized protein family UPF0029
JMW51_RS16455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMW51_RS16470	COG0488	(ABC) transporter
JMW51_RS16475	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMW51_RS16480	COG0750	zinc metalloprotease
JMW51_RS16490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMW51_RS16500	COG1473	amidohydrolase
JMW51_RS16525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMW51_RS16535	COG1191	sigma factor activity
JMW51_RS16540	COG2172	sigma factor antagonist activity
JMW51_RS16545	COG1366	Belongs to the anti-sigma-factor antagonist family
JMW51_RS16550	COG0243	molybdopterin cofactor binding
JMW51_RS16555	COG1028	Short-chain dehydrogenase reductase Sdr
JMW51_RS16585	COG0513	Belongs to the DEAD box helicase family
JMW51_RS16590	COG0530	calcium, potassium:sodium antiporter activity
JMW51_RS16600	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JMW51_RS16605	COG0778	Nitroreductase
JMW51_RS16615	COG0301	tRNA thio-modification
JMW51_RS16625	COG1126	abc transporter atp-binding protein
JMW51_RS16630	COG0765	amino acid transport
JMW51_RS16635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMW51_RS16640	COG0210	DNA helicase
JMW51_RS16660	COG1360	Flagellar Motor Protein
JMW51_RS16665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JMW51_RS16675	COG1349	DNA-binding transcription factor activity
JMW51_RS16680	COG3192	ethanolamine utilization protein
JMW51_RS16690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JMW51_RS16690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMW51_RS16705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMW51_RS16725	COG0095	Lipoate-protein ligase
JMW51_RS16745	COG0509	glycine decarboxylation via glycine cleavage system
JMW51_RS16775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMW51_RS16780	COG0646	methionine synthase
JMW51_RS16780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JMW51_RS16790	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JMW51_RS16795	COG3404	Formiminotransferase-cyclodeaminase
JMW51_RS16800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JMW51_RS16810	COG1151	hydroxylamine reductase activity
JMW51_RS16815	COG0280	phosphate acetyltransferase
JMW51_RS16820	COG0110	maltose O-acetyltransferase activity
JMW51_RS16825	COG0583	DNA-binding transcription factor activity
JMW51_RS16850	COG0018	arginyl-trna synthetase
JMW51_RS16855	COG1683	Conserved Protein
JMW51_RS16860	COG1193	negative regulation of DNA recombination
JMW51_RS16865	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW51_RS16870	COG3706	GGDEF domain
JMW51_RS16880	COG1051	belongs to the nudix hydrolase family
JMW51_RS16890	COG0826	peptidase U32
JMW51_RS16910	COG0072	phenylalanine-tRNA ligase activity
JMW51_RS16910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMW51_RS16915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JMW51_RS16920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMW51_RS16925	COG0569	domain protein
JMW51_RS16930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JMW51_RS16950	COG0789	Transcriptional regulator
JMW51_RS16995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JMW51_RS17000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JMW51_RS17005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JMW51_RS17015	COG1595	DNA-templated transcription, initiation
JMW51_RS17050	COG2205	protein histidine kinase activity
JMW51_RS17050	COG0745	RESPONSE REGULATOR receiver
JMW51_RS17050	COG3292	Two component regulator propeller
JMW51_RS17055	COG0745	RESPONSE REGULATOR receiver
JMW51_RS17135	COG0038	chloride channel
JMW51_RS17155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMW51_RS17165	COG4946	Tricorn protease homolog
JMW51_RS17165	COG1506	peptidase
JMW51_RS17165	COG0823	Involved in the tonB-independent uptake of proteins
JMW51_RS17170	COG4946	Tricorn protease homolog
JMW51_RS17170	COG1506	peptidase
JMW51_RS17170	COG0823	Involved in the tonB-independent uptake of proteins
JMW51_RS17175	COG1802	Transcriptional regulator
JMW51_RS17180	COG1131	(ABC) transporter
JMW51_RS17235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JMW51_RS17255	COG0305	Participates in initiation and elongation during chromosome replication
JMW51_RS17295	COG4978	Transcriptional regulator
JMW51_RS17295	COG0789	Transcriptional regulator
JMW51_RS17330	COG0456	acetyltransferase
JMW51_RS17330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JMW51_RS17345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JMW51_RS17355	COG3546	catalase activity
JMW51_RS17370	COG1475	DNA binding
JMW51_RS17375	COG3969	phosphoadenosine phosphosulfate
JMW51_RS17415	COG2199	diguanylate cyclase activity
JMW51_RS17420	COG1716	ATPase activity
JMW51_RS17420	COG5001	Diguanylate cyclase
JMW51_RS17425	COG0574	Belongs to the PEP-utilizing enzyme family
JMW51_RS17425	COG3848	Pyruvate phosphate dikinase
JMW51_RS17430	COG1309	transcriptional regulator
JMW51_RS17475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMW51_RS17480	COG4399	Belongs to the UPF0754 family
JMW51_RS17480	COG4399	Belongs to the UPF0754 family
JMW51_RS17510	COG1744	ABC transporter substrate-binding protein PnrA-like
JMW51_RS17520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JMW51_RS17525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JMW51_RS17530	COG1067	ATP-dependent peptidase activity
JMW51_RS17535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMW51_RS17550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JMW51_RS17560	COG2066	Belongs to the glutaminase family
JMW51_RS17565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMW51_RS17580	COG0681	Belongs to the peptidase S26 family
JMW51_RS17585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMW51_RS17585	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JMW51_RS17590	COG2339	peptidase activity
JMW51_RS17640	COG2201	protein-glutamate methylesterase activity
JMW51_RS17650	COG0835	chemotaxis
JMW51_RS17655	COG0643	Histidine kinase
JMW51_RS17655	COG2198	Histidine kinase
JMW51_RS17660	COG0840	transmembrane signaling receptor activity
JMW51_RS17670	COG0835	chemotaxis
JMW51_RS17675	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JMW51_RS17680	COG1776	CheC inhibitor of MCP methylation
JMW51_RS17685	COG2201	protein-glutamate methylesterase activity
JMW51_RS17695	COG2378	regulation of single-species biofilm formation
JMW51_RS17715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JMW51_RS17720	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMW51_RS17745	COG2205	protein histidine kinase activity
JMW51_RS17765	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JMW51_RS17765	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JMW51_RS17770	COG1686	Belongs to the peptidase S11 family
JMW51_RS17780	COG5002	protein histidine kinase activity
JMW51_RS17790	COG3716	PTS system mannose fructose sorbose family IID component
JMW51_RS17800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMW51_RS17810	COG1063	alcohol dehydrogenase
JMW51_RS17825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JMW51_RS17830	COG0745	RESPONSE REGULATOR receiver
JMW51_RS17835	COG5002	protein histidine kinase activity
JMW51_RS17840	COG1136	(ABC) transporter
JMW51_RS17845	COG0577	efflux transmembrane transporter activity
JMW51_RS17845	COG1136	(ABC) transporter
JMW51_RS17850	COG5002	protein histidine kinase activity
JMW51_RS17855	COG0745	RESPONSE REGULATOR receiver
JMW51_RS17870	COG1131	(ABC) transporter
JMW51_RS17895	COG0768	penicillin binding
JMW51_RS17975	COG1595	DNA-templated transcription, initiation
JMW51_RS18045	COG1131	(ABC) transporter
JMW51_RS18065	COG0745	RESPONSE REGULATOR receiver
JMW51_RS18070	COG5002	protein histidine kinase activity
JMW51_RS18080	COG1136	(ABC) transporter
JMW51_RS18090	COG3973	AAA domain
JMW51_RS18100	COG1051	belongs to the nudix hydrolase family
JMW51_RS18115	COG1757	Na H antiporter
JMW51_RS18120	COG3457	Alanine racemase
JMW51_RS18130	COG5012	cobalamin binding