locus-tag	class	description
DDG61_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DDG61_RS00010	COG0592	DNA-directed DNA polymerase activity
DDG61_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DDG61_RS00025	COG0187	DNA topoisomerase II activity
DDG61_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDG61_RS00045	COG1366	Belongs to the anti-sigma-factor antagonist family
DDG61_RS00055	COG1191	sigma factor activity
DDG61_RS00105	COG1827	regulation of RNA biosynthetic process
DDG61_RS00110	COG0668	transmembrane transport
DDG61_RS00115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDG61_RS00120	COG0590	tRNA wobble adenosine to inosine editing
DDG61_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDG61_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DDG61_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDG61_RS00155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDG61_RS00395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DDG61_RS00400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDG61_RS00405	COG4463	regulation of RNA biosynthetic process
DDG61_RS00410	COG3880	PFAM UvrB UvrC protein
DDG61_RS00415	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DDG61_RS00420	COG0542	response to heat
DDG61_RS00425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DDG61_RS00430	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DDG61_RS00435	COG4956	integral membrane protein (PIN domain superfamily)
DDG61_RS00455	COG3507	Belongs to the glycosyl hydrolase 43 family
DDG61_RS00465	COG2390	Transcriptional regulator
DDG61_RS00470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DDG61_RS00475	COG0022	dehydrogenase e1 component
DDG61_RS00480	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDG61_RS00485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDG61_RS00490	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS00490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS00500	COG3414	Phosphotransferase system galactitol-specific IIB component
DDG61_RS00505	COG3775	system Galactitol-specific IIC component
DDG61_RS00520	COG0095	Lipoate-protein ligase
DDG61_RS00525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DDG61_RS00530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DDG61_RS00535	COG0442	prolyl-tRNA aminoacylation
DDG61_RS00540	COG0442	prolyl-tRNA aminoacylation
DDG61_RS00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDG61_RS00555	COG0215	cysteine-tRNA ligase activity
DDG61_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDG61_RS00575	COG3688	RNA-binding protein containing a PIN domain
DDG61_RS00585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDG61_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDG61_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
DDG61_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDG61_RS00610	COG0081	regulation of translation
DDG61_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DDG61_RS00620	COG0222	ribosome binding
DDG61_RS00630	COG0085	RNA polymerase activity
DDG61_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DDG61_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDG61_RS00645	COG0049	tRNA binding
DDG61_RS00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDG61_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDG61_RS00660	COG0051	transcription antitermination factor activity, RNA binding
DDG61_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDG61_RS00670	COG0088	Forms part of the polypeptide exit tunnel
DDG61_RS00675	COG0089	rRNA binding
DDG61_RS00680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DDG61_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDG61_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DDG61_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DDG61_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDG61_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
DDG61_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DDG61_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DDG61_RS00720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DDG61_RS00725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DDG61_RS00730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDG61_RS00735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DDG61_RS00740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DDG61_RS00745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DDG61_RS00750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDG61_RS00755	COG1841	ribosomal large subunit assembly
DDG61_RS00760	COG0200	Binds to the 23S rRNA
DDG61_RS00770	COG0563	adenylate kinase activity
DDG61_RS00775	COG0024	Methionine aminopeptidase
DDG61_RS00785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDG61_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDG61_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DDG61_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DDG61_RS00805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDG61_RS00810	COG0202	RNA polymerase activity
DDG61_RS00815	COG0203	ribosomal protein L17
DDG61_RS00820	COG1122	ATPase activity
DDG61_RS00825	COG1122	ATPase activity
DDG61_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DDG61_RS00835	COG0101	tRNA pseudouridine synthase activity
DDG61_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDG61_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDG61_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS01095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DDG61_RS01110	COG0280	phosphate acetyltransferase
DDG61_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDG61_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDG61_RS01155	COG2897	thiosulfate sulfurtransferase activity
DDG61_RS01165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDG61_RS01170	COG2385	sporulation resulting in formation of a cellular spore
DDG61_RS01180	COG1609	Transcriptional regulator
DDG61_RS01185	COG1077	Cell shape determining protein MreB Mrl
DDG61_RS01190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DDG61_RS01200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDG61_RS01205	COG3949	Membrane
DDG61_RS01210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDG61_RS01215	COG1040	competence protein
DDG61_RS01220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS01220	COG3711	transcriptional antiterminator
DDG61_RS01225	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDG61_RS01230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS01235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS01245	COG1446	asparaginase
DDG61_RS01250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS01255	COG3142	Participates in the control of copper homeostasis
DDG61_RS01260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DDG61_RS01265	COG0653	protein targeting
DDG61_RS01270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DDG61_RS01275	COG2183	response to ionizing radiation
DDG61_RS01280	COG1228	amidohydrolase
DDG61_RS01295	COG0802	atpase or kinase
DDG61_RS01300	COG1214	PFAM Peptidase M22, glycoprotease
DDG61_RS01305	COG0456	acetyltransferase
DDG61_RS01310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDG61_RS01350	COG1473	amidohydrolase
DDG61_RS01370	COG0534	Mate efflux family protein
DDG61_RS01375	COG0488	(ABC) transporter
DDG61_RS01380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DDG61_RS01390	COG2221	Nitrite and sulphite reductase 4Fe-4S
DDG61_RS01400	COG1151	hydroxylamine reductase activity
DDG61_RS01415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DDG61_RS01455	COG0540	Belongs to the ATCase OTCase family
DDG61_RS01460	COG0543	2 iron, 2 sulfur cluster binding
DDG61_RS01465	COG0167	dihydroorotate dehydrogenase activity
DDG61_RS01470	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DDG61_RS01480	COG0583	DNA-binding transcription factor activity
DDG61_RS01495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDG61_RS01500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DDG61_RS01505	COG0459	protein refolding
DDG61_RS01510	COG1691	(AIR) carboxylase
DDG61_RS01515	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DDG61_RS01520	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DDG61_RS01525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDG61_RS01525	COG0519	Catalyzes the synthesis of GMP from XMP
DDG61_RS01560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDG61_RS01565	COG2771	luxR family
DDG61_RS01565	COG2200	EAL domain
DDG61_RS01580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS01585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS01595	COG1011	Hydrolase
DDG61_RS01610	COG0778	Nitroreductase
DDG61_RS01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDG61_RS01620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDG61_RS01625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DDG61_RS01630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDG61_RS01635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDG61_RS01640	COG0138	bifunctional purine biosynthesis protein purh
DDG61_RS01645	COG0151	Belongs to the GarS family
DDG61_RS01650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDG61_RS01655	COG0741	lytic transglycosylase activity
DDG61_RS01660	COG1728	Protein conserved in bacteria
DDG61_RS01690	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DDG61_RS01695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DDG61_RS01710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DDG61_RS01720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DDG61_RS01725	COG0463	Glycosyl transferase, family 2
DDG61_RS01730	COG0560	Phosphoserine phosphatase
DDG61_RS01735	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DDG61_RS01750	COG4786	Flagellar basal body rod
DDG61_RS01760	COG1677	Flagellar hook-basal body complex protein FliE
DDG61_RS01765	COG1766	The M ring may be actively involved in energy transduction
DDG61_RS01770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DDG61_RS01780	COG1157	protein secretion by the type III secretion system
DDG61_RS01795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DDG61_RS01800	COG4786	Flagellar basal body rod
DDG61_RS01810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DDG61_RS01815	COG1360	Flagellar Motor Protein
DDG61_RS01830	COG1338	Plays a role in the flagellum-specific transport system
DDG61_RS01840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DDG61_RS01845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DDG61_RS01850	COG1419	protein localization to endoplasmic reticulum
DDG61_RS01860	COG1191	sigma factor activity
DDG61_RS01875	COG4786	Flagellar basal body rod
DDG61_RS01890	COG1776	CheC inhibitor of MCP methylation
DDG61_RS01890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DDG61_RS01905	COG1454	alcohol dehydrogenase
DDG61_RS01910	COG1533	DNA photolyase activity
DDG61_RS01925	COG1733	regulation of RNA biosynthetic process
DDG61_RS01940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDG61_RS01945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS01945	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS01950	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS01950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS01975	COG3716	PTS system mannose fructose sorbose family IID component
DDG61_RS01985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS01995	COG3620	sequence-specific DNA binding
DDG61_RS02005	COG1131	(ABC) transporter
DDG61_RS02025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DDG61_RS02030	COG1609	Transcriptional regulator
DDG61_RS02035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDG61_RS02040	COG1879	ABC-type sugar transport system periplasmic component
DDG61_RS02045	COG1129	ABC transporter
DDG61_RS02050	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDG61_RS02055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS02065	COG1473	amidohydrolase
DDG61_RS02110	COG2217	Heavy metal translocating P-type atpase
DDG61_RS02130	COG0586	Pfam SNARE associated Golgi protein
DDG61_RS02160	COG2205	protein histidine kinase activity
DDG61_RS02165	COG0745	RESPONSE REGULATOR receiver
DDG61_RS02190	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DDG61_RS02200	COG1122	ATPase activity
DDG61_RS02205	COG0210	DNA helicase
DDG61_RS02235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DDG61_RS02260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDG61_RS02265	COG1674	ftsk spoiiie
DDG61_RS02275	COG2946	Replication initiation factor
DDG61_RS02305	COG0791	NLP P60 protein
DDG61_RS02305	COG0741	lytic transglycosylase activity
DDG61_RS02375	COG1454	alcohol dehydrogenase
DDG61_RS02375	COG1012	belongs to the aldehyde dehydrogenase family
DDG61_RS02385	COG1136	(ABC) transporter
DDG61_RS02395	COG3290	protein histidine kinase activity
DDG61_RS02425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDG61_RS02430	COG2357	RelA SpoT domain protein
DDG61_RS02450	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DDG61_RS02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS02475	COG2190	(PTS) system
DDG61_RS02475	COG1263	PTS System
DDG61_RS02480	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS02485	COG3711	transcriptional antiterminator
DDG61_RS02490	COG0367	asparagine synthase
DDG61_RS02505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDG61_RS02530	COG1960	acyl-CoA dehydrogenase activity
DDG61_RS02535	COG2086	electron transfer activity
DDG61_RS02540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDG61_RS02545	COG3829	transcription factor binding
DDG61_RS02550	COG0191	fructose-bisphosphate aldolase activity
DDG61_RS02625	COG3620	sequence-specific DNA binding
DDG61_RS02735	COG1484	DNA-dependent DNA replication
DDG61_RS02770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DDG61_RS02815	COG0358	DNA primase activity
DDG61_RS02865	COG0791	NLP P60 protein
DDG61_RS02865	COG1388	LysM domain
DDG61_RS02865	COG3103	Sh3 type 3 domain protein
DDG61_RS02880	COG0551	DNA topoisomerase type I activity
DDG61_RS02880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDG61_RS02935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDG61_RS02945	COG3901	Regulator of nitric oxide reductase transcription
DDG61_RS02945	COG0348	domain, Protein
DDG61_RS02955	COG1136	(ABC) transporter
DDG61_RS02970	COG5002	protein histidine kinase activity
DDG61_RS03000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DDG61_RS03015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDG61_RS03075	COG3829	transcription factor binding
DDG61_RS03080	COG3804	dihydrodipicolinate reductase
DDG61_RS03090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDG61_RS03100	COG5012	cobalamin binding
DDG61_RS03110	COG3457	Alanine racemase
DDG61_RS03115	COG1757	Na H antiporter
DDG61_RS03135	COG3973	AAA domain
DDG61_RS03140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDG61_RS03155	COG1136	(ABC) transporter
DDG61_RS03165	COG5002	protein histidine kinase activity
DDG61_RS03170	COG0745	RESPONSE REGULATOR receiver
DDG61_RS03175	COG1309	transcriptional regulator
DDG61_RS03190	COG1131	(ABC) transporter
DDG61_RS03205	COG1737	Transcriptional regulator
DDG61_RS03215	COG0561	phosphatase activity
DDG61_RS03220	COG0366	Alpha amylase catalytic
DDG61_RS03240	COG0768	penicillin binding
DDG61_RS03255	COG0655	NAD(P)H dehydrogenase (quinone) activity
DDG61_RS03285	COG1131	(ABC) transporter
DDG61_RS03305	COG5002	protein histidine kinase activity
DDG61_RS03315	COG1136	(ABC) transporter
DDG61_RS03320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDG61_RS03330	COG0745	RESPONSE REGULATOR receiver
DDG61_RS03335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDG61_RS03350	COG1063	alcohol dehydrogenase
DDG61_RS03360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS03370	COG3716	PTS system mannose fructose sorbose family IID component
DDG61_RS03390	COG1686	Belongs to the peptidase S11 family
DDG61_RS03395	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS03395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS03415	COG2205	protein histidine kinase activity
DDG61_RS03440	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDG61_RS03445	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DDG61_RS03470	COG2378	regulation of single-species biofilm formation
DDG61_RS03485	COG2201	protein-glutamate methylesterase activity
DDG61_RS03490	COG1776	CheC inhibitor of MCP methylation
DDG61_RS03495	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DDG61_RS03500	COG0835	chemotaxis
DDG61_RS03510	COG0840	transmembrane signaling receptor activity
DDG61_RS03515	COG2198	Histidine kinase
DDG61_RS03515	COG0643	Histidine kinase
DDG61_RS03520	COG0835	chemotaxis
DDG61_RS03530	COG2201	protein-glutamate methylesterase activity
DDG61_RS03580	COG2339	peptidase activity
DDG61_RS03585	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DDG61_RS03585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDG61_RS03590	COG0681	Belongs to the peptidase S26 family
DDG61_RS03605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDG61_RS03615	COG2066	Belongs to the glutaminase family
DDG61_RS03625	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DDG61_RS03645	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDG61_RS03650	COG1067	ATP-dependent peptidase activity
DDG61_RS03655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DDG61_RS03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DDG61_RS03670	COG1744	ABC transporter substrate-binding protein PnrA-like
DDG61_RS03695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDG61_RS03750	COG1309	transcriptional regulator
DDG61_RS03755	COG3848	Pyruvate phosphate dikinase
DDG61_RS03755	COG0574	Belongs to the PEP-utilizing enzyme family
DDG61_RS03770	COG3706	GGDEF domain
DDG61_RS03850	COG3969	phosphoadenosine phosphosulfate
DDG61_RS03855	COG1475	DNA binding
DDG61_RS03870	COG3546	catalase activity
DDG61_RS03885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDG61_RS03900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DDG61_RS03925	COG3279	Response regulator of the LytR AlgR family
DDG61_RS03930	COG0577	efflux transmembrane transporter activity
DDG61_RS03935	COG1136	(ABC) transporter
DDG61_RS03955	COG0789	Transcriptional regulator
DDG61_RS03955	COG4978	Transcriptional regulator
DDG61_RS04005	COG0305	Participates in initiation and elongation during chromosome replication
DDG61_RS04025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DDG61_RS04030	COG0534	Mate efflux family protein
DDG61_RS04040	COG4335	DNA alkylation repair
DDG61_RS04095	COG0745	RESPONSE REGULATOR receiver
DDG61_RS04100	COG2205	protein histidine kinase activity
DDG61_RS04105	COG1131	(ABC) transporter
DDG61_RS04115	COG3177	Filamentation induced by cAMP protein fic
DDG61_RS04120	COG1802	Transcriptional regulator
DDG61_RS04125	COG1506	peptidase
DDG61_RS04125	COG4946	Tricorn protease homolog
DDG61_RS04125	COG0823	Involved in the tonB-independent uptake of proteins
DDG61_RS04130	COG1506	peptidase
DDG61_RS04130	COG0823	Involved in the tonB-independent uptake of proteins
DDG61_RS04130	COG4946	Tricorn protease homolog
DDG61_RS04145	COG1737	Transcriptional regulator
DDG61_RS04150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS04155	COG0383	alpha-mannosidase activity
DDG61_RS04160	COG0366	Alpha amylase catalytic
DDG61_RS04200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DDG61_RS04210	COG1136	(ABC) transporter
DDG61_RS04215	COG1132	(ABC) transporter
DDG61_RS04220	COG2801	Transposase and inactivated derivatives
DDG61_RS04235	COG0038	chloride channel
DDG61_RS04340	COG2205	protein histidine kinase activity
DDG61_RS04380	COG1595	DNA-templated transcription, initiation
DDG61_RS04395	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DDG61_RS04430	COG2814	Major facilitator Superfamily
DDG61_RS04435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDG61_RS04440	COG1609	Transcriptional regulator
DDG61_RS04455	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDG61_RS04460	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DDG61_RS04505	COG0789	Transcriptional regulator
DDG61_RS04525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDG61_RS04530	COG0569	domain protein
DDG61_RS04535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDG61_RS04540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DDG61_RS04545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDG61_RS04545	COG0072	phenylalanine-tRNA ligase activity
DDG61_RS04560	COG0826	peptidase U32
DDG61_RS04570	COG1051	belongs to the nudix hydrolase family
DDG61_RS04580	COG3706	GGDEF domain
DDG61_RS04585	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDG61_RS04590	COG1193	negative regulation of DNA recombination
DDG61_RS04595	COG1683	Conserved Protein
DDG61_RS04600	COG0018	arginyl-trna synthetase
DDG61_RS04615	COG1032	radical SAM domain protein
DDG61_RS04625	COG0583	DNA-binding transcription factor activity
DDG61_RS04635	COG0280	phosphate acetyltransferase
DDG61_RS04640	COG1151	hydroxylamine reductase activity
DDG61_RS04650	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DDG61_RS04655	COG3404	Formiminotransferase-cyclodeaminase
DDG61_RS04660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DDG61_RS04670	COG0646	methionine synthase
DDG61_RS04670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DDG61_RS04675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDG61_RS04705	COG0509	glycine decarboxylation via glycine cleavage system
DDG61_RS04725	COG0095	Lipoate-protein ligase
DDG61_RS04745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDG61_RS04760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDG61_RS04760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DDG61_RS04770	COG3192	ethanolamine utilization protein
DDG61_RS04775	COG1349	DNA-binding transcription factor activity
DDG61_RS04785	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DDG61_RS04790	COG1360	Flagellar Motor Protein
DDG61_RS04810	COG0210	DNA helicase
DDG61_RS04815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDG61_RS04820	COG0765	amino acid transport
DDG61_RS04825	COG1126	abc transporter atp-binding protein
DDG61_RS04835	COG0301	tRNA thio-modification
DDG61_RS04845	COG0778	Nitroreductase
DDG61_RS04850	COG3300	MHYT domain
DDG61_RS04850	COG5001	Diguanylate cyclase
DDG61_RS04855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DDG61_RS04865	COG0530	calcium, potassium:sodium antiporter activity
DDG61_RS04870	COG0513	Belongs to the DEAD box helicase family
DDG61_RS04875	COG0243	molybdopterin cofactor binding
DDG61_RS04880	COG1366	Belongs to the anti-sigma-factor antagonist family
DDG61_RS04885	COG2172	sigma factor antagonist activity
DDG61_RS04890	COG1191	sigma factor activity
DDG61_RS04900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDG61_RS04925	COG1473	amidohydrolase
DDG61_RS04935	COG2226	methyltransferase
DDG61_RS04950	COG0295	cytidine deaminase activity
DDG61_RS04955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDG61_RS04965	COG0750	zinc metalloprotease
DDG61_RS04970	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS04975	COG0488	(ABC) transporter
DDG61_RS04990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDG61_RS05005	COG1739	Uncharacterized protein family UPF0029
DDG61_RS05015	COG0730	response to heat
DDG61_RS05020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDG61_RS05025	COG0217	transcriptional regulatory protein
DDG61_RS05030	COG1024	Enoyl-CoA hydratase
DDG61_RS05035	COG2610	gluconate transmembrane transporter activity
DDG61_RS05050	COG2086	electron transfer activity
DDG61_RS05055	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDG61_RS05100	COG2186	Transcriptional regulator
DDG61_RS05105	COG2814	Major facilitator Superfamily
DDG61_RS05110	COG2190	(PTS) system
DDG61_RS05110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS05110	COG1263	PTS System
DDG61_RS05115	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS05125	COG0745	RESPONSE REGULATOR receiver
DDG61_RS05130	COG5002	protein histidine kinase activity
DDG61_RS05150	COG1592	Rubrerythrin
DDG61_RS05160	COG2033	superoxide reductase activity
DDG61_RS05165	COG0069	glutamate synthase activity
DDG61_RS05185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDG61_RS05195	COG0473	3-isopropylmalate dehydrogenase activity
DDG61_RS05200	COG1846	Transcriptional regulator
DDG61_RS05225	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDG61_RS05230	COG0138	bifunctional purine biosynthesis protein purh
DDG61_RS05240	COG0438	transferase activity, transferring glycosyl groups
DDG61_RS05240	COG0297	glycogen (starch) synthase activity
DDG61_RS05255	COG3620	sequence-specific DNA binding
DDG61_RS05275	COG0582	viral genome integration into host DNA
DDG61_RS05315	COG0534	Mate efflux family protein
DDG61_RS05335	COG1473	amidohydrolase
DDG61_RS05340	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DDG61_RS05355	COG0601	transmembrane transport
DDG61_RS05360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDG61_RS05370	COG0444	Belongs to the ABC transporter superfamily
DDG61_RS05375	COG4608	Belongs to the ABC transporter superfamily
DDG61_RS05380	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS05380	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS05400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS05410	COG1486	melibiose metabolic process
DDG61_RS05420	COG1073	alpha beta
DDG61_RS05430	COG1910	domain protein
DDG61_RS05435	COG0725	ABC transporter, periplasmic molybdate-binding protein
DDG61_RS05440	COG4149	molybdate abc transporter
DDG61_RS05445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DDG61_RS05450	COG0110	maltose O-acetyltransferase activity
DDG61_RS05460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDG61_RS05465	COG4120	Belongs to the binding-protein-dependent transport system permease family
DDG61_RS05470	COG2984	ABC transporter substrate binding protein
DDG61_RS05485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DDG61_RS05485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DDG61_RS05500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDG61_RS05505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DDG61_RS05510	COG0297	glycogen (starch) synthase activity
DDG61_RS05515	COG0058	SHG alpha-glucan phosphorylase activity
DDG61_RS05525	COG1802	Transcriptional regulator
DDG61_RS05535	COG1982	Orn Lys Arg decarboxylase major
DDG61_RS05540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DDG61_RS05545	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DDG61_RS05550	COG0010	Belongs to the arginase family
DDG61_RS05585	COG4868	Belongs to the UPF0371 family
DDG61_RS05590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDG61_RS05600	COG1174	glycine betaine transport
DDG61_RS05605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDG61_RS05635	COG0534	Mate efflux family protein
DDG61_RS05640	COG0539	negative regulation of cytoplasmic translation
DDG61_RS05640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DDG61_RS05645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDG61_RS05655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDG61_RS05660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DDG61_RS05665	COG0066	3-isopropylmalate dehydratase activity
DDG61_RS05670	COG0473	3-isopropylmalate dehydrogenase activity
DDG61_RS05685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DDG61_RS05700	COG3447	MASE1 domain protein
DDG61_RS05700	COG5002	protein histidine kinase activity
DDG61_RS05700	COG5001	Diguanylate cyclase
DDG61_RS05725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDG61_RS05730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DDG61_RS05740	COG0281	malic enzyme
DDG61_RS05750	COG0745	RESPONSE REGULATOR receiver
DDG61_RS05755	COG5002	protein histidine kinase activity
DDG61_RS05760	COG1136	(ABC) transporter
DDG61_RS05760	COG0577	efflux transmembrane transporter activity
DDG61_RS05780	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DDG61_RS05785	COG0363	glucosamine-6-phosphate deaminase activity
DDG61_RS05800	COG5002	protein histidine kinase activity
DDG61_RS05805	COG5001	Diguanylate cyclase
DDG61_RS05815	COG0789	Transcriptional regulator
DDG61_RS05815	COG4978	Transcriptional regulator
DDG61_RS05825	COG1132	(ABC) transporter
DDG61_RS05845	COG2364	Membrane
DDG61_RS05855	COG3842	ATPase activity
DDG61_RS05860	COG1176	ABC-type spermidine putrescine transport system, permease component I
DDG61_RS05865	COG1177	transmembrane transport
DDG61_RS05870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DDG61_RS05880	COG5298	Protein conserved in bacteria
DDG61_RS05885	COG1215	transferase activity, transferring glycosyl groups
DDG61_RS05900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DDG61_RS05930	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS05935	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS05935	COG2247	cell wall binding repeat
DDG61_RS05945	COG0210	DNA helicase
DDG61_RS05955	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DDG61_RS05960	COG1074	ATP-dependent DNA helicase activity
DDG61_RS05965	COG0420	3'-5' exonuclease activity
DDG61_RS05970	COG0419	ATPase involved in DNA repair
DDG61_RS05975	COG4536	flavin adenine dinucleotide binding
DDG61_RS05985	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDG61_RS05995	COG0622	Phosphoesterase
DDG61_RS06000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDG61_RS06005	COG1131	(ABC) transporter
DDG61_RS06025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDG61_RS06030	COG1960	acyl-CoA dehydrogenase activity
DDG61_RS06035	COG2086	electron transfer activity
DDG61_RS06040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDG61_RS06055	COG0183	Belongs to the thiolase family
DDG61_RS06060	COG0564	pseudouridine synthase activity
DDG61_RS06070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDG61_RS06125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDG61_RS06130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS06135	COG4224	UPF0291 protein
DDG61_RS06140	COG1362	aminopeptidase activity
DDG61_RS06145	COG2188	Transcriptional regulator
DDG61_RS06165	COG3715	PTS system
DDG61_RS06170	COG3716	PTS system mannose fructose sorbose family IID component
DDG61_RS06175	COG0583	DNA-binding transcription factor activity
DDG61_RS06195	COG3414	Phosphotransferase system galactitol-specific IIB component
DDG61_RS06200	COG1132	(ABC) transporter
DDG61_RS06210	COG1473	amidohydrolase
DDG61_RS06225	COG3279	Response regulator of the LytR AlgR family
DDG61_RS06240	COG1882	Formate acetyltransferase
DDG61_RS06245	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DDG61_RS06250	COG1396	sequence-specific DNA binding
DDG61_RS06275	COG3708	Transcriptional regulator
DDG61_RS06275	COG2207	Transcriptional regulator
DDG61_RS06315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDG61_RS06315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDG61_RS06320	COG0237	dephospho-CoA kinase activity
DDG61_RS06345	COG0346	lactoylglutathione lyase activity
DDG61_RS06350	COG0791	NLP P60 protein
DDG61_RS06360	COG4656	Part of a membrane complex involved in electron transport
DDG61_RS06365	COG4658	electron transport chain
DDG61_RS06370	COG4659	FMN binding
DDG61_RS06375	COG4660	Part of a membrane complex involved in electron transport
DDG61_RS06380	COG4657	Part of a membrane complex involved in electron transport
DDG61_RS06385	COG1245	4Fe-4S binding domain
DDG61_RS06385	COG2878	Part of a membrane complex involved in electron transport
DDG61_RS06390	COG0424	maF-like protein
DDG61_RS06395	COG2003	Belongs to the UPF0758 family
DDG61_RS06400	COG1077	Cell shape determining protein MreB Mrl
DDG61_RS06420	COG0850	regulation of cytokinetic process
DDG61_RS06425	COG2894	cell division
DDG61_RS06430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DDG61_RS06435	COG0772	Belongs to the SEDS family
DDG61_RS06440	COG1803	Methylglyoxal synthase
DDG61_RS06450	COG0426	domain, Protein
DDG61_RS06470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DDG61_RS06480	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DDG61_RS06485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DDG61_RS06495	COG0460	homoserine dehydrogenase
DDG61_RS06505	COG3314	Sporulation integral membrane protein YlbJ
DDG61_RS06510	COG2186	Transcriptional regulator
DDG61_RS06515	COG3875	lactate racemase activity
DDG61_RS06520	COG2086	electron transfer activity
DDG61_RS06530	COG0277	FAD linked oxidase domain protein
DDG61_RS06535	COG1323	Belongs to the UPF0348 family
DDG61_RS06540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DDG61_RS06550	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DDG61_RS06560	COG0416	fatty acid biosynthetic process
DDG61_RS06565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DDG61_RS06575	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDG61_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
DDG61_RS06585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDG61_RS06590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DDG61_RS06595	COG3706	GGDEF domain
DDG61_RS06610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDG61_RS06625	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DDG61_RS06630	COG3854	ATPases associated with a variety of cellular activities
DDG61_RS06670	COG1302	Protein conserved in bacteria
DDG61_RS06675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDG61_RS06680	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDG61_RS06685	COG1570	exodeoxyribonuclease VII activity
DDG61_RS06700	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DDG61_RS06705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDG61_RS06710	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DDG61_RS06715	COG0497	DNA recombination
DDG61_RS06725	COG0456	acetyltransferase
DDG61_RS06730	COG0456	acetyltransferase
DDG61_RS06735	COG0750	zinc metalloprotease
DDG61_RS06755	COG0463	Glycosyl transferase, family 2
DDG61_RS06770	COG0494	nUDIX hydrolase
DDG61_RS06780	COG4974	Belongs to the 'phage' integrase family
DDG61_RS06785	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DDG61_RS06800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DDG61_RS06805	COG4122	O-methyltransferase activity
DDG61_RS06810	COG0826	peptidase U32
DDG61_RS06815	COG0768	penicillin binding
DDG61_RS06965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDG61_RS06975	COG0571	ribonuclease III activity
DDG61_RS06985	COG1196	nuclear chromosome segregation
DDG61_RS06990	COG0552	protein localization to endoplasmic reticulum
DDG61_RS07000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DDG61_RS07005	COG0228	four-way junction DNA binding
DDG61_RS07015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDG61_RS07020	COG0336	Belongs to the RNA methyltransferase TrmD family
DDG61_RS07025	COG0335	large ribosomal subunit rRNA binding
DDG61_RS07035	COG1114	Component of the transport system for branched-chain amino acids
DDG61_RS07050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDG61_RS07080	COG1131	(ABC) transporter
DDG61_RS07085	COG2197	response regulator
DDG61_RS07090	COG4585	Histidine kinase
DDG61_RS07095	COG0792	nuclease activity
DDG61_RS07100	COG0606	chelatase, subunit chli
DDG61_RS07105	COG0758	DNA mediated transformation
DDG61_RS07110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDG61_RS07120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DDG61_RS07130	COG1959	2 iron, 2 sulfur cluster binding
DDG61_RS07140	COG0822	iron-sulfur transferase activity
DDG61_RS07145	COG0482	sulfurtransferase activity
DDG61_RS07150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DDG61_RS07155	COG4472	Bacterial protein of unknown function (DUF965)
DDG61_RS07165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDG61_RS07170	COG3906	Belongs to the UPF0473 family
DDG61_RS07175	COG0735	belongs to the Fur family
DDG61_RS07185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DDG61_RS07195	COG1686	Belongs to the peptidase S11 family
DDG61_RS07205	COG1917	Cupin 2, conserved barrel domain protein
DDG61_RS07205	COG2207	Transcriptional regulator
DDG61_RS07210	COG1994	Peptidase M50
DDG61_RS07220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DDG61_RS07275	COG0779	Required for maturation of 30S ribosomal subunits
DDG61_RS07280	COG0195	Participates in both transcription termination and antitermination
DDG61_RS07285	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DDG61_RS07295	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DDG61_RS07305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DDG61_RS07310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDG61_RS07315	COG0196	riboflavin kinase activity
DDG61_RS07325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DDG61_RS07330	COG1307	EDD domain protein, DegV family
DDG61_RS07335	COG1185	polyribonucleotide nucleotidyltransferase activity
DDG61_RS07340	COG0726	polysaccharide deacetylase
DDG61_RS07345	COG0612	Peptidase, M16
DDG61_RS07350	COG1873	PFAM PRC-barrel domain
DDG61_RS07355	COG0527	aspartate kinase activity
DDG61_RS07360	COG0740	serine-type endopeptidase activity
DDG61_RS07370	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DDG61_RS07375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDG61_RS07385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DDG61_RS07390	COG1418	mRNA catabolic process
DDG61_RS07405	COG1968	undecaprenyl-diphosphatase activity
DDG61_RS07415	COG0114	fumarate hydratase activity
DDG61_RS07425	COG1263	PTS System
DDG61_RS07425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS07435	COG1486	melibiose metabolic process
DDG61_RS07440	COG0436	Aminotransferase
DDG61_RS07450	COG0708	Exodeoxyribonuclease III
DDG61_RS07465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDG61_RS07490	COG1131	(ABC) transporter
DDG61_RS07520	COG1278	Cold shock
DDG61_RS07530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDG61_RS07610	COG3299	homolog of phage Mu protein gp47
DDG61_RS07615	COG3778	Protein conserved in bacteria
DDG61_RS07660	COG1396	sequence-specific DNA binding
DDG61_RS07665	COG2814	Major facilitator Superfamily
DDG61_RS07675	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDG61_RS07680	COG3273	potassium ion transport
DDG61_RS07680	COG0471	metal ion transport
DDG61_RS07685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DDG61_RS07690	COG1914	H( )-stimulated, divalent metal cation uptake system
DDG61_RS07695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DDG61_RS07700	COG1984	allophanate hydrolase subunit 2
DDG61_RS07705	COG1396	sequence-specific DNA binding
DDG61_RS07710	COG4948	Mandelate Racemase Muconate Lactonizing
DDG61_RS07770	COG1619	proteins homologs of microcin C7 resistance protein MccF
DDG61_RS07785	COG0584	glycerophosphoryl diester phosphodiesterase
DDG61_RS07805	COG0488	(ABC) transporter
DDG61_RS07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS07820	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDG61_RS07825	COG1546	Belongs to the CinA family
DDG61_RS07825	COG1058	Belongs to the CinA family
DDG61_RS07840	COG3829	transcription factor binding
DDG61_RS07850	COG1242	4 iron, 4 sulfur cluster binding
DDG61_RS07885	COG2801	Transposase and inactivated derivatives
DDG61_RS07890	COG5001	Diguanylate cyclase
DDG61_RS07890	COG3447	MASE1 domain protein
DDG61_RS07890	COG5002	protein histidine kinase activity
DDG61_RS07895	COG2203	Gaf domain
DDG61_RS07895	COG2199	diguanylate cyclase activity
DDG61_RS07905	COG0789	Transcriptional regulator
DDG61_RS07905	COG4978	Transcriptional regulator
DDG61_RS07920	COG1285	pathogenesis
DDG61_RS07925	COG1335	isochorismatase
DDG61_RS07945	COG0726	polysaccharide deacetylase
DDG61_RS07960	COG0450	alkyl hydroperoxide reductase
DDG61_RS07975	COG2720	vancomycin resistance protein
DDG61_RS07980	COG3829	transcription factor binding
DDG61_RS07995	COG1346	cytolysis
DDG61_RS08000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDG61_RS08010	COG2340	Cysteine-rich secretory protein family
DDG61_RS08015	COG0726	polysaccharide deacetylase
DDG61_RS08020	COG0512	Glutamine amidotransferase of anthranilate synthase
DDG61_RS08025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DDG61_RS08040	COG0302	gtp cyclohydrolase
DDG61_RS08045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DDG61_RS08050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DDG61_RS08055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DDG61_RS08060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DDG61_RS08065	COG0358	DNA primase activity
DDG61_RS08070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDG61_RS08075	COG2384	SAM-dependent methyltransferase
DDG61_RS08080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDG61_RS08085	COG0655	NAD(P)H dehydrogenase (quinone) activity
DDG61_RS08105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS08115	COG0745	RESPONSE REGULATOR receiver
DDG61_RS08120	COG3850	Histidine kinase
DDG61_RS08120	COG5002	protein histidine kinase activity
DDG61_RS08125	COG0577	efflux transmembrane transporter activity
DDG61_RS08125	COG1136	(ABC) transporter
DDG61_RS08155	COG1132	(ABC) transporter
DDG61_RS08160	COG1132	(ABC) transporter
DDG61_RS08165	COG1592	Rubrerythrin
DDG61_RS08165	COG1773	rubredoxin
DDG61_RS08175	COG0412	Dienelactone hydrolase
DDG61_RS08210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDG61_RS08245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DDG61_RS08250	COG2011	ABC-type metal ion transport system permease component
DDG61_RS08260	COG5002	protein histidine kinase activity
DDG61_RS08265	COG2094	Belongs to the DNA glycosylase MPG family
DDG61_RS08270	COG1396	sequence-specific DNA binding
DDG61_RS08275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDG61_RS08280	COG4086	secreted protein
DDG61_RS08300	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDG61_RS08310	COG1131	(ABC) transporter
DDG61_RS08320	COG0534	Mate efflux family protein
DDG61_RS08335	COG3901	Regulator of nitric oxide reductase transcription
DDG61_RS08335	COG0348	domain, Protein
DDG61_RS08360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DDG61_RS08365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DDG61_RS08375	COG5001	Diguanylate cyclase
DDG61_RS08385	COG4978	Transcriptional regulator
DDG61_RS08385	COG0789	Transcriptional regulator
DDG61_RS08390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DDG61_RS08410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDG61_RS08415	COG0726	polysaccharide deacetylase
DDG61_RS08425	COG1592	Rubrerythrin
DDG61_RS08425	COG1773	rubredoxin
DDG61_RS08430	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDG61_RS08435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DDG61_RS08440	COG0577	efflux transmembrane transporter activity
DDG61_RS08445	COG1136	(ABC) transporter
DDG61_RS08455	COG2205	protein histidine kinase activity
DDG61_RS08460	COG0745	RESPONSE REGULATOR receiver
DDG61_RS08465	COG1136	(ABC) transporter
DDG61_RS08470	COG0577	efflux transmembrane transporter activity
DDG61_RS08475	COG0405	Gamma-glutamyltransferase
DDG61_RS08490	COG0493	'glutamate synthase
DDG61_RS08490	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDG61_RS08500	COG1136	(ABC) transporter
DDG61_RS08505	COG0577	efflux transmembrane transporter activity
DDG61_RS08545	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DDG61_RS08550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DDG61_RS08555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDG61_RS08560	COG0131	Imidazoleglycerol-phosphate dehydratase
DDG61_RS08565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDG61_RS08570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DDG61_RS08575	COG0107	imidazoleglycerol-phosphate synthase activity
DDG61_RS08580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DDG61_RS08580	COG0140	phosphoribosyl-ATP diphosphatase activity
DDG61_RS08585	COG0531	amino acid
DDG61_RS08600	COG1595	DNA-templated transcription, initiation
DDG61_RS08615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DDG61_RS08630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DDG61_RS08635	COG0028	Belongs to the TPP enzyme family
DDG61_RS08640	COG0582	viral genome integration into host DNA
DDG61_RS08670	COG3617	BRO family, N-terminal domain
DDG61_RS08685	COG1476	TRANSCRIPTIONal
DDG61_RS08765	COG5484	DNA packaging
DDG61_RS08775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDG61_RS08885	COG4193	domain, Protein
DDG61_RS08895	COG3628	GPW Gp25 family protein
DDG61_RS08900	COG3299	homolog of phage Mu protein gp47
DDG61_RS08945	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS08945	COG1388	LysM domain
DDG61_RS08960	COG3546	catalase activity
DDG61_RS08965	COG1331	Highly conserved protein containing a thioredoxin domain
DDG61_RS08975	COG2267	carboxylic ester hydrolase activity
DDG61_RS08980	COG1136	(ABC) transporter
DDG61_RS09010	COG0454	-acetyltransferase
DDG61_RS09025	COG0456	acetyltransferase
DDG61_RS09065	COG1388	LysM domain
DDG61_RS09065	COG3584	3D domain protein
DDG61_RS09075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDG61_RS09080	COG1295	ribonuclease BN
DDG61_RS09085	COG5002	protein histidine kinase activity
DDG61_RS09090	COG0460	homoserine dehydrogenase
DDG61_RS09100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DDG61_RS09105	COG2267	carboxylic ester hydrolase activity
DDG61_RS09110	COG5566	PFAM Mor transcription activator
DDG61_RS09120	COG2971	BadF BadG BcrA BcrD
DDG61_RS09130	COG1129	ABC transporter
DDG61_RS09135	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDG61_RS09145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDG61_RS09155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DDG61_RS09160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DDG61_RS09165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DDG61_RS09170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DDG61_RS09175	COG1045	serine acetyltransferase
DDG61_RS09180	COG1141	Ferredoxin
DDG61_RS09200	COG0352	thiamine-phosphate diphosphorylase activity
DDG61_RS09200	COG0351	phosphomethylpyrimidine kinase
DDG61_RS09205	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DDG61_RS09210	COG0352	thiamine-phosphate diphosphorylase activity
DDG61_RS09215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS09235	COG1725	Transcriptional regulator
DDG61_RS09265	COG0402	S-adenosylhomocysteine deaminase activity
DDG61_RS09275	COG4555	ABC transporter
DDG61_RS09280	COG1668	transmembrane transport
DDG61_RS09285	COG5001	Diguanylate cyclase
DDG61_RS09285	COG3300	MHYT domain
DDG61_RS09290	COG1725	Transcriptional regulator
DDG61_RS09295	COG1131	(ABC) transporter
DDG61_RS09310	COG0668	transmembrane transport
DDG61_RS09320	COG0426	domain, Protein
DDG61_RS09340	COG0367	asparagine synthase
DDG61_RS09345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDG61_RS09360	COG2310	stress, protein
DDG61_RS09375	COG3853	Toxic anion resistance protein (TelA)
DDG61_RS09405	COG5505	Protein of unknown function (DUF819)
DDG61_RS09415	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDG61_RS09420	COG4605	iron ion homeostasis
DDG61_RS09425	COG4604	ABC transporter, ATP-binding protein
DDG61_RS09430	COG4607	ABC-type enterochelin transport system periplasmic component
DDG61_RS09435	COG5001	Diguanylate cyclase
DDG61_RS09435	COG4251	negative regulation of phosphorylation
DDG61_RS09435	COG3706	GGDEF domain
DDG61_RS09435	COG2203	Gaf domain
DDG61_RS09450	COG0095	Lipoate-protein ligase
DDG61_RS09455	COG1757	Na H antiporter
DDG61_RS09470	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DDG61_RS09475	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DDG61_RS09480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDG61_RS09485	COG3123	guanosine phosphorylase activity
DDG61_RS09490	COG0402	S-adenosylhomocysteine deaminase activity
DDG61_RS09505	COG1396	sequence-specific DNA binding
DDG61_RS09515	COG0584	glycerophosphoryl diester phosphodiesterase
DDG61_RS09520	COG0110	maltose O-acetyltransferase activity
DDG61_RS09535	COG1131	(ABC) transporter
DDG61_RS09545	COG0745	RESPONSE REGULATOR receiver
DDG61_RS09550	COG2205	protein histidine kinase activity
DDG61_RS09570	COG1733	regulation of RNA biosynthetic process
DDG61_RS09575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DDG61_RS09605	COG1309	transcriptional regulator
DDG61_RS09640	COG0745	RESPONSE REGULATOR receiver
DDG61_RS09645	COG5002	protein histidine kinase activity
DDG61_RS09650	COG3118	belongs to the thioredoxin family
DDG61_RS09680	COG1115	amino acid carrier protein
DDG61_RS09690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDG61_RS09690	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DDG61_RS09705	COG0514	ATP-dependent DNA helicase (RecQ)
DDG61_RS09710	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DDG61_RS09725	COG2022	thiamine diphosphate biosynthetic process
DDG61_RS09730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DDG61_RS09740	COG1288	antiporter activity
DDG61_RS09760	COG0393	Putative heavy-metal-binding
DDG61_RS09765	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDG61_RS09775	COG0315	cyclic pyranopterin monophosphate synthase activity
DDG61_RS09850	COG1283	sodium-dependent phosphate transmembrane transporter activity
DDG61_RS09875	COG5012	cobalamin binding
DDG61_RS09880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DDG61_RS09890	COG1011	Hydrolase
DDG61_RS09895	COG1396	sequence-specific DNA binding
DDG61_RS09895	COG1917	Cupin 2, conserved barrel domain protein
DDG61_RS09900	COG2610	gluconate transmembrane transporter activity
DDG61_RS09905	COG5002	protein histidine kinase activity
DDG61_RS09910	COG2204	response regulator
DDG61_RS09950	COG0786	glutamate:sodium symporter activity
DDG61_RS09965	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DDG61_RS09970	COG1924	4 iron, 4 sulfur cluster binding
DDG61_RS09975	COG2247	cell wall binding repeat
DDG61_RS09975	COG2385	sporulation resulting in formation of a cellular spore
DDG61_RS09985	COG1309	transcriptional regulator
DDG61_RS10010	COG0242	peptide deformylase activity
DDG61_RS10050	COG3326	Membrane
DDG61_RS10065	COG0494	nUDIX hydrolase
DDG61_RS10115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DDG61_RS10120	COG0765	amino acid transport
DDG61_RS10130	COG1393	Belongs to the ArsC family
DDG61_RS10140	COG1606	tRNA processing
DDG61_RS10145	COG0116	Belongs to the methyltransferase superfamily
DDG61_RS10160	COG5002	protein histidine kinase activity
DDG61_RS10160	COG3850	Histidine kinase
DDG61_RS10170	COG0137	argininosuccinate synthase activity
DDG61_RS10180	COG0789	Transcriptional regulator
DDG61_RS10190	COG2323	membrane
DDG61_RS10205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DDG61_RS10230	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDG61_RS10235	COG0583	DNA-binding transcription factor activity
DDG61_RS10250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDG61_RS10265	COG1609	Transcriptional regulator
DDG61_RS10275	COG1621	beta-fructofuranosidase activity
DDG61_RS10280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDG61_RS10295	COG2814	Major facilitator Superfamily
DDG61_RS10325	COG0406	alpha-ribazole phosphatase activity
DDG61_RS10330	COG2081	HI0933 family
DDG61_RS10335	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DDG61_RS10340	COG0204	Acyl-transferase
DDG61_RS10345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DDG61_RS10370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DDG61_RS10375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DDG61_RS10380	COG3022	response to hydroperoxide
DDG61_RS10395	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DDG61_RS10400	COG1846	Transcriptional regulator
DDG61_RS10405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDG61_RS10410	COG2205	protein histidine kinase activity
DDG61_RS10420	COG0598	Magnesium transport protein CorA
DDG61_RS10430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DDG61_RS10440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDG61_RS10445	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DDG61_RS10450	COG0077	Prephenate dehydratase
DDG61_RS10450	COG1605	Chorismate mutase
DDG61_RS10455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DDG61_RS10465	COG0287	Prephenate dehydrogenase
DDG61_RS10475	COG3706	GGDEF domain
DDG61_RS10510	COG3708	Transcriptional regulator
DDG61_RS10510	COG2207	Transcriptional regulator
DDG61_RS10550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDG61_RS10555	COG2226	methyltransferase
DDG61_RS10560	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DDG61_RS10590	COG2131	deaminase
DDG61_RS10620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDG61_RS10670	COG4303	Ethanolamine ammonia lyase large subunit
DDG61_RS10675	COG4302	ethanolamine ammonia-lyase activity
DDG61_RS10690	COG1012	belongs to the aldehyde dehydrogenase family
DDG61_RS10690	COG1454	alcohol dehydrogenase
DDG61_RS10705	COG4869	propanediol catabolic process
DDG61_RS10715	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
DDG61_RS10725	COG3192	ethanolamine utilization protein
DDG61_RS10730	COG4766	ethanolamine catabolic process
DDG61_RS10735	COG2207	Transcriptional regulator
DDG61_RS10755	COG1473	amidohydrolase
DDG61_RS10760	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DDG61_RS10765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDG61_RS10770	COG1116	anion transmembrane transporter activity
DDG61_RS10790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDG61_RS10795	COG4974	Belongs to the 'phage' integrase family
DDG61_RS10810	COG2359	stage V sporulation protein S
DDG61_RS10815	COG0825	malonyl-CoA metabolic process
DDG61_RS10820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DDG61_RS10825	COG0439	Biotin carboxylase
DDG61_RS10830	COG0511	ligase activity, forming carbon-carbon bonds
DDG61_RS10850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDG61_RS10875	COG1136	(ABC) transporter
DDG61_RS10885	COG2205	protein histidine kinase activity
DDG61_RS10890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDG61_RS10895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DDG61_RS10915	COG1136	(ABC) transporter
DDG61_RS10915	COG0577	efflux transmembrane transporter activity
DDG61_RS10920	COG2205	protein histidine kinase activity
DDG61_RS10925	COG0745	RESPONSE REGULATOR receiver
DDG61_RS10935	COG0745	RESPONSE REGULATOR receiver
DDG61_RS10940	COG5002	protein histidine kinase activity
DDG61_RS10945	COG1136	(ABC) transporter
DDG61_RS10945	COG0577	efflux transmembrane transporter activity
DDG61_RS10980	COG1811	Na channel or pump
DDG61_RS10985	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DDG61_RS11000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS11005	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DDG61_RS11010	COG1923	regulation of RNA biosynthetic process
DDG61_RS11015	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DDG61_RS11020	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DDG61_RS11025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DDG61_RS11030	COG1116	anion transmembrane transporter activity
DDG61_RS11035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDG61_RS11040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDG61_RS11055	COG1733	regulation of RNA biosynthetic process
DDG61_RS11060	COG0384	phenazine biosynthesis protein PhzF
DDG61_RS11065	COG0494	nUDIX hydrolase
DDG61_RS11075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDG61_RS11080	COG2247	cell wall binding repeat
DDG61_RS11080	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS11145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DDG61_RS11170	COG0730	response to heat
DDG61_RS11175	COG2207	Transcriptional regulator
DDG61_RS11180	COG0789	Transcriptional regulator
DDG61_RS11195	COG1404	Belongs to the peptidase S8 family
DDG61_RS11215	COG0129	dihydroxy-acid dehydratase activity
DDG61_RS11245	COG2207	Transcriptional regulator
DDG61_RS11250	COG2814	Major facilitator Superfamily
DDG61_RS11270	COG1725	Transcriptional regulator
DDG61_RS11295	COG1794	racemase activity, acting on amino acids and derivatives
DDG61_RS11305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDG61_RS11310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DDG61_RS11315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DDG61_RS11320	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DDG61_RS11330	COG0456	acetyltransferase
DDG61_RS11340	COG1309	transcriptional regulator
DDG61_RS11360	COG3655	Transcriptional regulator
DDG61_RS11375	COG0745	RESPONSE REGULATOR receiver
DDG61_RS11380	COG1737	Transcriptional regulator
DDG61_RS11385	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DDG61_RS11390	COG1187	pseudouridine synthase activity
DDG61_RS11395	COG0628	permease
DDG61_RS11405	COG0019	diaminopimelate decarboxylase activity
DDG61_RS11410	COG0527	aspartate kinase activity
DDG61_RS11440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDG61_RS11445	COG1597	lipid kinase activity
DDG61_RS11475	COG0582	viral genome integration into host DNA
DDG61_RS11485	COG0488	(ABC) transporter
DDG61_RS11500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDG61_RS11510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDG61_RS11510	COG2080	2 iron, 2 sulfur cluster binding
DDG61_RS11520	COG2233	PERMEase
DDG61_RS11535	COG0167	dihydroorotate dehydrogenase activity
DDG61_RS11540	COG0402	S-adenosylhomocysteine deaminase activity
DDG61_RS11560	COG0402	S-adenosylhomocysteine deaminase activity
DDG61_RS11585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDG61_RS11610	COG3829	transcription factor binding
DDG61_RS11620	COG1401	restriction endodeoxyribonuclease activity
DDG61_RS11635	COG4708	membrane
DDG61_RS11645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDG61_RS11645	COG2080	2 iron, 2 sulfur cluster binding
DDG61_RS11680	COG1131	(ABC) transporter
DDG61_RS11690	COG2252	PERMEase
DDG61_RS11695	COG0534	Mate efflux family protein
DDG61_RS11705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDG61_RS11710	COG1349	DNA-binding transcription factor activity
DDG61_RS11720	COG5002	protein histidine kinase activity
DDG61_RS11725	COG0745	RESPONSE REGULATOR receiver
DDG61_RS11730	COG2217	Heavy metal translocating P-type atpase
DDG61_RS11745	COG1217	gtp-binding protein TYPA
DDG61_RS11750	COG0492	ferredoxin-NADP+ reductase activity
DDG61_RS11790	COG1247	-acetyltransferase
DDG61_RS11815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DDG61_RS11820	COG0750	zinc metalloprotease
DDG61_RS11825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DDG61_RS11850	COG4589	Belongs to the CDS family
DDG61_RS11865	COG0233	cytoplasmic translational termination
DDG61_RS11870	COG0528	UMP kinase activity
DDG61_RS11875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DDG61_RS11880	COG0052	Belongs to the universal ribosomal protein uS2 family
DDG61_RS11885	COG1686	Belongs to the peptidase S11 family
DDG61_RS11900	COG1971	Probably functions as a manganese efflux pump
DDG61_RS11905	COG1193	negative regulation of DNA recombination
DDG61_RS11920	COG2720	vancomycin resistance protein
DDG61_RS11940	COG1363	Peptidase, m42
DDG61_RS11950	COG1160	GTP binding
DDG61_RS11955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DDG61_RS12005	COG0039	L-malate dehydrogenase activity
DDG61_RS12015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDG61_RS12015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDG61_RS12025	COG1151	hydroxylamine reductase activity
DDG61_RS12045	COG0437	4 iron, 4 sulfur cluster binding
DDG61_RS12060	COG2945	thiolester hydrolase activity
DDG61_RS12060	COG0596	Alpha beta hydrolase
DDG61_RS12090	COG1705	Flagellar rod assembly protein muramidase FlgJ
DDG61_RS12095	COG1554	hydrolase, family 65, central catalytic
DDG61_RS12100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDG61_RS12110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DDG61_RS12120	COG2247	cell wall binding repeat
DDG61_RS12120	COG2385	sporulation resulting in formation of a cellular spore
DDG61_RS12130	COG1528	Iron-storage protein
DDG61_RS12150	COG0674	pyruvate-flavodoxin oxidoreductase activity
DDG61_RS12150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DDG61_RS12160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDG61_RS12175	COG1309	transcriptional regulator
DDG61_RS12185	COG0628	permease
DDG61_RS12190	COG1012	belongs to the aldehyde dehydrogenase family
DDG61_RS12205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDG61_RS12230	COG0288	reversible hydration of carbon dioxide
DDG61_RS12250	COG0710	3-dehydroquinate dehydratase activity
DDG61_RS12265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDG61_RS12325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDG61_RS12330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDG61_RS12335	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DDG61_RS12350	COG2203	Gaf domain
DDG61_RS12350	COG3706	GGDEF domain
DDG61_RS12350	COG4251	negative regulation of phosphorylation
DDG61_RS12350	COG5001	Diguanylate cyclase
DDG61_RS12355	COG0017	Asparaginyl-tRNA synthetase
DDG61_RS12365	COG1404	Belongs to the peptidase S8 family
DDG61_RS12370	COG1404	Belongs to the peptidase S8 family
DDG61_RS12380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDG61_RS12395	COG1509	lysine 2,3-aminomutase activity
DDG61_RS12400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS12405	COG1794	racemase activity, acting on amino acids and derivatives
DDG61_RS12425	COG0662	Cupin 2, conserved barrel domain protein
DDG61_RS12430	COG3104	oligopeptide transport
DDG61_RS12435	COG0006	proline dipeptidase activity
DDG61_RS12440	COG3104	oligopeptide transport
DDG61_RS12445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDG61_RS12460	COG0723	plastoquinol--plastocyanin reductase activity
DDG61_RS12460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DDG61_RS12465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS12465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS12465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS12470	COG1105	Belongs to the carbohydrate kinase PfkB family
DDG61_RS12475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS12475	COG3711	transcriptional antiterminator
DDG61_RS12480	COG2365	Tyrosine phosphatase family
DDG61_RS12500	COG1115	amino acid carrier protein
DDG61_RS12505	COG0235	Class ii aldolase
DDG61_RS12510	COG0235	Class ii aldolase
DDG61_RS12515	COG1063	alcohol dehydrogenase
DDG61_RS12520	COG3775	system Galactitol-specific IIC component
DDG61_RS12525	COG3414	Phosphotransferase system galactitol-specific IIB component
DDG61_RS12530	COG2213	PTS system mannitol-specific
DDG61_RS12530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS12535	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS12535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS12545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS12550	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DDG61_RS12560	COG5002	protein histidine kinase activity
DDG61_RS12605	COG2267	carboxylic ester hydrolase activity
DDG61_RS12650	COG3299	homolog of phage Mu protein gp47
DDG61_RS12670	COG0582	viral genome integration into host DNA
DDG61_RS12695	COG3620	sequence-specific DNA binding
DDG61_RS12720	COG3842	ATPase activity
DDG61_RS12740	COG2205	protein histidine kinase activity
DDG61_RS12745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDG61_RS12750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDG61_RS12755	COG0698	ribose 5-phosphate isomerase
DDG61_RS12760	COG3958	Transketolase
DDG61_RS12765	COG3959	Transketolase, thiamine diphosphate binding domain
DDG61_RS12780	COG3775	system Galactitol-specific IIC component
DDG61_RS12785	COG3414	Phosphotransferase system galactitol-specific IIB component
DDG61_RS12795	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DDG61_RS12795	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DDG61_RS12800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDG61_RS12805	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDG61_RS12810	COG0246	Mannitol dehydrogenase
DDG61_RS12820	COG3711	transcriptional antiterminator
DDG61_RS12830	COG0516	GMP reductase activity
DDG61_RS12830	COG0517	IMP dehydrogenase activity
DDG61_RS12835	COG3853	Toxic anion resistance protein (TelA)
DDG61_RS12845	COG1454	alcohol dehydrogenase
DDG61_RS12850	COG0427	acetyl-CoA hydrolase
DDG61_RS12865	COG1012	belongs to the aldehyde dehydrogenase family
DDG61_RS12870	COG0427	acetyl-CoA hydrolase
DDG61_RS12875	COG2985	domain, Protein
DDG61_RS12875	COG0490	domain, Protein
DDG61_RS12875	COG0490	domain, Protein
DDG61_RS12875	COG2985	domain, Protein
DDG61_RS12880	COG0583	DNA-binding transcription factor activity
DDG61_RS12890	COG0006	proline dipeptidase activity
DDG61_RS12920	COG3118	belongs to the thioredoxin family
DDG61_RS12955	COG1116	anion transmembrane transporter activity
DDG61_RS12965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDG61_RS13005	COG0157	Belongs to the NadC ModD family
DDG61_RS13015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DDG61_RS13020	COG1966	Carbon starvation protein
DDG61_RS13035	COG0628	permease
DDG61_RS13045	COG2364	Membrane
DDG61_RS13050	COG3426	butyrate kinase activity
DDG61_RS13075	COG2199	diguanylate cyclase activity
DDG61_RS13080	COG2203	Gaf domain
DDG61_RS13080	COG2199	diguanylate cyclase activity
DDG61_RS13120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDG61_RS13120	COG0072	phenylalanine-tRNA ligase activity
DDG61_RS13125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DDG61_RS13130	COG2176	DNA-directed DNA polymerase activity
DDG61_RS13150	COG0037	tRNA processing
DDG61_RS13165	COG3546	catalase activity
DDG61_RS13170	COG0791	NLP P60 protein
DDG61_RS13170	COG1388	LysM domain
DDG61_RS13170	COG3103	Sh3 type 3 domain protein
DDG61_RS13180	COG0551	DNA topoisomerase type I activity
DDG61_RS13180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDG61_RS13210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDG61_RS13210	COG0574	Belongs to the PEP-utilizing enzyme family
DDG61_RS13215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DDG61_RS13220	COG0517	IMP dehydrogenase activity
DDG61_RS13240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS13240	COG3711	transcriptional antiterminator
DDG61_RS13245	COG3732	PTS system glucitol sorbitol-specific
DDG61_RS13255	COG2207	Transcriptional regulator
DDG61_RS13270	COG1115	amino acid carrier protein
DDG61_RS13275	COG2223	nitrite transmembrane transporter activity
DDG61_RS13280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS13285	COG0280	phosphate acetyltransferase
DDG61_RS13305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DDG61_RS13305	COG0674	pyruvate-flavodoxin oxidoreductase activity
DDG61_RS13315	COG1414	Transcriptional regulator
DDG61_RS13325	COG0751	glycine-tRNA ligase activity
DDG61_RS13330	COG0752	glycyl-tRNA synthetase alpha subunit
DDG61_RS13340	COG1381	Involved in DNA repair and RecF pathway recombination
DDG61_RS13350	COG2239	Acts as a magnesium transporter
DDG61_RS13355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDG61_RS13360	COG0295	cytidine deaminase activity
DDG61_RS13365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DDG61_RS13370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DDG61_RS13375	COG1702	phosphate starvation-inducible protein PhoH
DDG61_RS13395	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DDG61_RS13400	COG1610	YqeY-like protein
DDG61_RS13405	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DDG61_RS13410	COG0537	adenosine 5'-monophosphoramidase activity
DDG61_RS13415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDG61_RS13420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DDG61_RS13425	COG2264	protein methyltransferase activity
DDG61_RS13465	COG3842	ATPase activity
DDG61_RS13470	COG2508	Transcriptional regulator
DDG61_RS13475	COG0477	Major facilitator Superfamily
DDG61_RS13490	COG0484	heat shock protein binding
DDG61_RS13495	COG0443	Heat shock 70 kDa protein
DDG61_RS13500	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DDG61_RS13505	COG1420	regulation of RNA biosynthetic process
DDG61_RS13510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDG61_RS13515	COG0531	amino acid
DDG61_RS13520	COG0617	tRNA 3'-terminal CCA addition
DDG61_RS13525	COG0481	GTPase activity
DDG61_RS13560	COG0268	Binds directly to 16S ribosomal RNA
DDG61_RS13570	COG2333	competence protein COMEC
DDG61_RS13570	COG0658	competence protein
DDG61_RS13590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DDG61_RS13595	COG3584	3D domain protein
DDG61_RS13595	COG1388	LysM domain
DDG61_RS13600	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDG61_RS13615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDG61_RS13620	COG0006	proline dipeptidase activity
DDG61_RS13625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS13630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS13640	COG3711	transcriptional antiterminator
DDG61_RS13640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS13645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS13650	COG1482	cell wall glycoprotein biosynthetic process
DDG61_RS13655	COG5002	protein histidine kinase activity
DDG61_RS13675	COG1555	photosystem II stabilization
DDG61_RS13680	COG1686	Belongs to the peptidase S11 family
DDG61_RS13690	COG0165	Argininosuccinate lyase
DDG61_RS13695	COG0561	phosphatase activity
DDG61_RS13700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDG61_RS13705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDG61_RS13710	COG1876	peptidase activity
DDG61_RS13715	COG1309	transcriptional regulator
DDG61_RS13720	COG2814	Major facilitator Superfamily
DDG61_RS13730	COG4977	sequence-specific DNA binding
DDG61_RS13740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS13740	COG1263	PTS System
DDG61_RS13745	COG3711	transcriptional antiterminator
DDG61_RS13750	COG1263	PTS System
DDG61_RS13750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS13750	COG2190	(PTS) system
DDG61_RS13755	COG0251	oxidation-reduction process
DDG61_RS13760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DDG61_RS13855	COG0495	leucyl-tRNA aminoacylation
DDG61_RS13860	COG0799	negative regulation of ribosome biogenesis
DDG61_RS13865	COG1713	HD superfamily hydrolase involved in NAD metabolism
DDG61_RS13870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DDG61_RS13875	COG2137	regulation of response to DNA damage stimulus
DDG61_RS13880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDG61_RS13885	COG1309	transcriptional regulator
DDG61_RS13910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DDG61_RS13920	COG0577	efflux transmembrane transporter activity
DDG61_RS13920	COG1136	(ABC) transporter
DDG61_RS13930	COG0745	RESPONSE REGULATOR receiver
DDG61_RS13935	COG0737	Belongs to the 5'-nucleotidase family
DDG61_RS13945	COG1234	tRNA 3'-trailer cleavage
DDG61_RS13950	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDG61_RS13955	COG1823	symporter activity
DDG61_RS13980	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DDG61_RS13980	COG4124	Belongs to the glycosyl hydrolase 26 family
DDG61_RS13990	COG0395	ABC-type sugar transport system, permease component
DDG61_RS14010	COG4821	SIS domain
DDG61_RS14040	COG0742	ribosomal rna small subunit methyltransferase
DDG61_RS14045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DDG61_RS14050	COG1461	Dihydroxyacetone kinase
DDG61_RS14055	COG1302	Protein conserved in bacteria
DDG61_RS14060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDG61_RS14075	COG0789	Transcriptional regulator
DDG61_RS14080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS14080	COG3711	transcriptional antiterminator
DDG61_RS14090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS14090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS14090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS14095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS14100	COG0383	alpha-mannosidase activity
DDG61_RS14125	COG1564	THIamine pyrophosphokinase
DDG61_RS14130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDG61_RS14135	COG1162	GTPase activity
DDG61_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
DDG61_RS14145	COG2815	serine threonine protein kinase
DDG61_RS14145	COG0515	serine threonine protein kinase
DDG61_RS14155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDG61_RS14160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DDG61_RS14160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDG61_RS14165	COG2738	Putative neutral zinc metallopeptidase
DDG61_RS14175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DDG61_RS14180	COG0242	peptide deformylase activity
DDG61_RS14185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDG61_RS14190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDG61_RS14195	COG1758	RNA polymerase activity
DDG61_RS14200	COG0194	GDP metabolic process
DDG61_RS14205	COG1561	YicC-like family, N-terminal region
DDG61_RS14210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DDG61_RS14220	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DDG61_RS14225	COG0488	(ABC) transporter
DDG61_RS14235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DDG61_RS14240	COG0564	pseudouridine synthase activity
DDG61_RS14245	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DDG61_RS14255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DDG61_RS14265	COG2801	Transposase and inactivated derivatives
DDG61_RS14270	COG1966	Carbon starvation protein
DDG61_RS14275	COG3279	Response regulator of the LytR AlgR family
DDG61_RS14280	COG3275	phosphorelay sensor kinase activity
DDG61_RS14285	COG0180	Tryptophanyl-tRNA synthetase
DDG61_RS14290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDG61_RS14295	COG0531	amino acid
DDG61_RS14300	COG0006	proline dipeptidase activity
DDG61_RS14305	COG1307	EDD domain protein, DegV family
DDG61_RS14320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDG61_RS14325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDG61_RS14345	COG1799	cell septum assembly
DDG61_RS14350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DDG61_RS14370	COG3830	Belongs to the UPF0237 family
DDG61_RS14380	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DDG61_RS14385	COG2271	Major facilitator Superfamily
DDG61_RS14390	COG0531	amino acid
DDG61_RS14395	COG0006	proline dipeptidase activity
DDG61_RS14405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDG61_RS14410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DDG61_RS14415	COG1160	GTP binding
DDG61_RS14440	COG5002	protein histidine kinase activity
DDG61_RS14445	COG0745	RESPONSE REGULATOR receiver
DDG61_RS14455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDG61_RS14460	COG1873	PFAM PRC-barrel domain
DDG61_RS14465	COG1191	sigma factor activity
DDG61_RS14470	COG1191	sigma factor activity
DDG61_RS14485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DDG61_RS14490	COG3856	small basic protein
DDG61_RS14510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDG61_RS14515	COG0772	Belongs to the SEDS family
DDG61_RS14520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DDG61_RS14525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDG61_RS14530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDG61_RS14535	COG0768	penicillin binding
DDG61_RS14545	COG0275	rRNA processing
DDG61_RS14550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DDG61_RS14555	COG0612	Peptidase, M16
DDG61_RS14565	COG0012	GTP binding
DDG61_RS14580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDG61_RS14590	COG1263	PTS System
DDG61_RS14590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS14590	COG2190	(PTS) system
DDG61_RS14595	COG3711	transcriptional antiterminator
DDG61_RS14600	COG0025	NhaP-type Na H and K H
DDG61_RS14605	COG4608	Belongs to the ABC transporter superfamily
DDG61_RS14610	COG0444	Belongs to the ABC transporter superfamily
DDG61_RS14620	COG0601	transmembrane transport
DDG61_RS14625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDG61_RS14630	COG0583	DNA-binding transcription factor activity
DDG61_RS14635	COG0183	Belongs to the thiolase family
DDG61_RS14640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DDG61_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
DDG61_RS14655	COG2610	gluconate transmembrane transporter activity
DDG61_RS14660	COG2340	Cysteine-rich secretory protein family
DDG61_RS14675	COG4869	propanediol catabolic process
DDG61_RS14710	COG2081	HI0933 family
DDG61_RS14715	COG0671	phosphoesterase, PA-phosphatase related
DDG61_RS14725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDG61_RS14740	COG2502	aspartate--ammonia ligase
DDG61_RS14745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDG61_RS14750	COG1473	amidohydrolase
DDG61_RS14760	COG3366	ferrous iron transmembrane transporter activity
DDG61_RS14785	COG2252	PERMEase
DDG61_RS14790	COG0402	S-adenosylhomocysteine deaminase activity
DDG61_RS14800	COG2271	Major facilitator Superfamily
DDG61_RS14820	COG0583	DNA-binding transcription factor activity
DDG61_RS14830	COG1376	ErfK ybiS ycfS ynhG family protein
DDG61_RS14835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDG61_RS14840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDG61_RS14865	COG4509	Sortase family
DDG61_RS14890	COG3069	C4-dicarboxylate transmembrane transporter activity
DDG61_RS14895	COG0642	Histidine kinase
DDG61_RS14895	COG5002	protein histidine kinase activity
DDG61_RS14900	COG0745	RESPONSE REGULATOR receiver
DDG61_RS14915	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDG61_RS14920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDG61_RS14940	COG1937	Protein conserved in bacteria
DDG61_RS14955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDG61_RS14960	COG1757	Na H antiporter
DDG61_RS14970	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS14970	COG2247	cell wall binding repeat
DDG61_RS14975	COG0583	DNA-binding transcription factor activity
DDG61_RS14980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DDG61_RS14990	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DDG61_RS14995	COG0124	histidyl-tRNA synthetase
DDG61_RS15000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DDG61_RS15010	COG1490	D-aminoacyl-tRNA deacylase activity
DDG61_RS15015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDG61_RS15020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDG61_RS15025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DDG61_RS15025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DDG61_RS15070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS15095	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS15100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDG61_RS15115	COG1316	TRANSCRIPTIONal
DDG61_RS15120	COG1316	TRANSCRIPTIONal
DDG61_RS15125	COG1649	PFAM Uncharacterised BCR, COG1649
DDG61_RS15130	COG0791	NLP P60 protein
DDG61_RS15140	COG0438	transferase activity, transferring glycosyl groups
DDG61_RS15145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DDG61_RS15150	COG1215	transferase activity, transferring glycosyl groups
DDG61_RS15160	COG1215	transferase activity, transferring glycosyl groups
DDG61_RS15165	COG1215	transferase activity, transferring glycosyl groups
DDG61_RS15165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DDG61_RS15170	COG1216	Glycosyl transferase, family 2
DDG61_RS15190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDG61_RS15195	COG0728	peptidoglycan biosynthetic process
DDG61_RS15200	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS15200	COG2247	cell wall binding repeat
DDG61_RS15205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DDG61_RS15210	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS15225	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS15225	COG2247	cell wall binding repeat
DDG61_RS15235	COG2246	polysaccharide biosynthetic process
DDG61_RS15240	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS15240	COG2247	cell wall binding repeat
DDG61_RS15255	COG0653	protein targeting
DDG61_RS15290	COG2247	cell wall binding repeat
DDG61_RS15290	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS15310	COG0343	queuine tRNA-ribosyltransferase activity
DDG61_RS15320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DDG61_RS15325	COG2255	four-way junction helicase activity
DDG61_RS15330	COG0632	four-way junction helicase activity
DDG61_RS15335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DDG61_RS15360	COG2610	gluconate transmembrane transporter activity
DDG61_RS15365	COG2084	Dehydrogenase
DDG61_RS15385	COG1132	(ABC) transporter
DDG61_RS15405	COG0700	Nucleoside recognition
DDG61_RS15410	COG3366	ferrous iron transmembrane transporter activity
DDG61_RS15415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS15445	COG0436	Aminotransferase
DDG61_RS15450	COG0697	spore germination
DDG61_RS15465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDG61_RS15470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS15475	COG0076	glutamate decarboxylase activity
DDG61_RS15485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDG61_RS15490	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DDG61_RS15495	COG1473	amidohydrolase
DDG61_RS15500	COG3949	Membrane
DDG61_RS15515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDG61_RS15530	COG0604	alcohol dehydrogenase
DDG61_RS15540	COG1592	Rubrerythrin
DDG61_RS15545	COG0789	Transcriptional regulator
DDG61_RS15555	COG1664	Polymer-forming cytoskeletal
DDG61_RS15560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDG61_RS15560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DDG61_RS15565	COG1349	DNA-binding transcription factor activity
DDG61_RS15570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DDG61_RS15575	COG1696	Membrane protein involved in D-alanine export
DDG61_RS15580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DDG61_RS15590	COG0673	inositol 2-dehydrogenase activity
DDG61_RS15600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDG61_RS15605	COG1253	flavin adenine dinucleotide binding
DDG61_RS15610	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DDG61_RS15630	COG3829	transcription factor binding
DDG61_RS15630	COG3290	protein histidine kinase activity
DDG61_RS15635	COG2267	carboxylic ester hydrolase activity
DDG61_RS15645	COG0312	modulator of DNA gyrase
DDG61_RS15650	COG0312	modulator of DNA gyrase
DDG61_RS15675	COG2721	sulfolactate sulfo-lyase activity
DDG61_RS15680	COG5001	Diguanylate cyclase
DDG61_RS15680	COG4251	negative regulation of phosphorylation
DDG61_RS15680	COG2203	Gaf domain
DDG61_RS15680	COG3706	GGDEF domain
DDG61_RS15690	COG1120	ATPase activity
DDG61_RS15695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDG61_RS15700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDG61_RS15715	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDG61_RS15720	COG3394	polysaccharide catabolic process
DDG61_RS15725	COG1486	melibiose metabolic process
DDG61_RS15730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS15740	COG2188	Transcriptional regulator
DDG61_RS15745	COG0534	Mate efflux family protein
DDG61_RS15750	COG2199	diguanylate cyclase activity
DDG61_RS15760	COG3842	ATPase activity
DDG61_RS15765	COG1840	ABC-type Fe3 transport system, periplasmic component
DDG61_RS15770	COG1394	ATPase activity, coupled to movement of substances
DDG61_RS15775	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DDG61_RS15780	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DDG61_RS15795	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DDG61_RS15800	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDG61_RS15805	COG1269	ATP hydrolysis coupled proton transport
DDG61_RS15830	COG5001	Diguanylate cyclase
DDG61_RS15830	COG3300	MHYT domain
DDG61_RS15835	COG1012	belongs to the aldehyde dehydrogenase family
DDG61_RS15835	COG1454	alcohol dehydrogenase
DDG61_RS15845	COG2801	Transposase and inactivated derivatives
DDG61_RS15855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DDG61_RS15865	COG0318	PFAM AMP-dependent synthetase and ligase
DDG61_RS15870	COG0183	Belongs to the thiolase family
DDG61_RS15910	COG0577	efflux transmembrane transporter activity
DDG61_RS15915	COG1136	(ABC) transporter
DDG61_RS15920	COG1968	undecaprenyl-diphosphatase activity
DDG61_RS15925	COG2205	protein histidine kinase activity
DDG61_RS15930	COG0745	RESPONSE REGULATOR receiver
DDG61_RS15945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDG61_RS15960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDG61_RS15965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDG61_RS15975	COG1120	ATPase activity
DDG61_RS15980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDG61_RS15990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDG61_RS15995	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDG61_RS16000	COG2721	sulfolactate sulfo-lyase activity
DDG61_RS16020	COG1454	alcohol dehydrogenase
DDG61_RS16025	COG1376	ErfK ybiS ycfS ynhG family protein
DDG61_RS16040	COG2801	Transposase and inactivated derivatives
DDG61_RS16045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDG61_RS16050	COG0785	Cytochrome C biogenesis protein
DDG61_RS16055	COG1733	regulation of RNA biosynthetic process
DDG61_RS16075	COG0383	alpha-mannosidase activity
DDG61_RS16080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16095	COG3711	transcriptional antiterminator
DDG61_RS16095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16100	COG4975	Glucose uptake
DDG61_RS16130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DDG61_RS16145	COG0517	IMP dehydrogenase activity
DDG61_RS16145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DDG61_RS16150	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDG61_RS16155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16155	COG1263	PTS System
DDG61_RS16160	COG3711	transcriptional antiterminator
DDG61_RS16165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DDG61_RS16170	COG3118	belongs to the thioredoxin family
DDG61_RS16180	COG0384	phenazine biosynthesis protein PhzF
DDG61_RS16200	COG0542	response to heat
DDG61_RS16210	COG2267	carboxylic ester hydrolase activity
DDG61_RS16225	COG1737	Transcriptional regulator
DDG61_RS16245	COG2971	BadF BadG BcrA BcrD
DDG61_RS16250	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DDG61_RS16260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS16275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DDG61_RS16280	COG0642	Histidine kinase
DDG61_RS16295	COG1136	(ABC) transporter
DDG61_RS16305	COG2190	(PTS) system
DDG61_RS16320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16320	COG1263	PTS System
DDG61_RS16335	COG2115	Belongs to the xylose isomerase family
DDG61_RS16340	COG1070	Carbohydrate kinase
DDG61_RS16355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16360	COG3716	PTS system mannose fructose sorbose family IID component
DDG61_RS16390	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DDG61_RS16415	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DDG61_RS16420	COG0191	fructose-bisphosphate aldolase activity
DDG61_RS16425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16440	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS16450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS16460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16460	COG2213	PTS system mannitol-specific
DDG61_RS16465	COG1929	Belongs to the glycerate kinase type-1 family
DDG61_RS16470	COG0383	alpha-mannosidase activity
DDG61_RS16475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16485	COG3394	polysaccharide catabolic process
DDG61_RS16490	COG2190	(PTS) system
DDG61_RS16490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16490	COG1263	PTS System
DDG61_RS16495	COG2188	Transcriptional regulator
DDG61_RS16500	COG0366	Alpha amylase catalytic
DDG61_RS16510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DDG61_RS16525	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS16530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16530	COG2190	(PTS) system
DDG61_RS16530	COG1263	PTS System
DDG61_RS16535	COG3711	transcriptional antiterminator
DDG61_RS16545	COG1288	antiporter activity
DDG61_RS16550	COG1263	PTS System
DDG61_RS16550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDG61_RS16565	COG0561	phosphatase activity
DDG61_RS16570	COG1454	alcohol dehydrogenase
DDG61_RS16575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDG61_RS16580	COG3711	transcriptional antiterminator
DDG61_RS16580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DDG61_RS16590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDG61_RS16595	COG0205	6-phosphofructokinase activity
DDG61_RS16605	COG1473	amidohydrolase
DDG61_RS16610	COG1473	amidohydrolase
DDG61_RS16620	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS16625	COG2190	(PTS) system
DDG61_RS16625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16625	COG1263	PTS System
DDG61_RS16640	COG1819	glycosyl
DDG61_RS16645	COG3620	sequence-specific DNA binding
DDG61_RS16655	COG2223	nitrite transmembrane transporter activity
DDG61_RS16660	COG1695	Transcriptional regulator
DDG61_RS16670	COG0640	Transcriptional regulator
DDG61_RS16680	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS16685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16685	COG2190	(PTS) system
DDG61_RS16685	COG1263	PTS System
DDG61_RS16690	COG3711	transcriptional antiterminator
DDG61_RS16695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16695	COG1263	PTS System
DDG61_RS16700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DDG61_RS16710	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS16720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16725	COG3711	transcriptional antiterminator
DDG61_RS16730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS16730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DDG61_RS16735	COG0191	fructose-bisphosphate aldolase activity
DDG61_RS16740	COG2723	6-phospho-beta-galactosidase activity
DDG61_RS16745	COG2190	(PTS) system
DDG61_RS16745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS16745	COG1263	PTS System
DDG61_RS16750	COG3711	transcriptional antiterminator
DDG61_RS16775	COG0693	protein deglycase activity
DDG61_RS16790	COG4509	Sortase family
DDG61_RS16800	COG1136	(ABC) transporter
DDG61_RS16930	COG2003	Belongs to the UPF0758 family
DDG61_RS16965	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DDG61_RS16975	COG1388	LysM domain
DDG61_RS16975	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS17020	COG3299	homolog of phage Mu protein gp47
DDG61_RS17035	COG0791	NLP P60 protein
DDG61_RS17040	COG1652	LysM domain
DDG61_RS17090	COG0740	serine-type endopeptidase activity
DDG61_RS17150	COG0305	Participates in initiation and elongation during chromosome replication
DDG61_RS17175	COG1396	sequence-specific DNA binding
DDG61_RS17190	COG0582	viral genome integration into host DNA
DDG61_RS17200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DDG61_RS17225	COG1131	(ABC) transporter
DDG61_RS17235	COG0557	exoribonuclease II activity
DDG61_RS17250	COG1881	PFAM PEBP family protein
DDG61_RS17280	COG0148	phosphopyruvate hydratase activity
DDG61_RS17285	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DDG61_RS17290	COG0149	triose-phosphate isomerase activity
DDG61_RS17295	COG0126	phosphoglycerate kinase activity
DDG61_RS17305	COG2390	Transcriptional regulator
DDG61_RS17310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DDG61_RS17315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DDG61_RS17325	COG0167	dihydroorotate dehydrogenase activity
DDG61_RS17335	COG0402	S-adenosylhomocysteine deaminase activity
DDG61_RS17340	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DDG61_RS17360	COG3829	transcription factor binding
DDG61_RS17365	COG0251	oxidation-reduction process
DDG61_RS17380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DDG61_RS17385	COG0789	Transcriptional regulator
DDG61_RS17395	COG0860	N-Acetylmuramoyl-L-alanine amidase
DDG61_RS17395	COG2247	cell wall binding repeat
DDG61_RS17400	COG1136	(ABC) transporter
DDG61_RS17405	COG0577	efflux transmembrane transporter activity
DDG61_RS17410	COG4585	Histidine kinase
DDG61_RS17425	COG2207	Transcriptional regulator
DDG61_RS17430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDG61_RS17440	COG0789	Transcriptional regulator
DDG61_RS17465	COG2770	Histidine kinase
DDG61_RS17465	COG2205	protein histidine kinase activity
DDG61_RS17470	COG0745	RESPONSE REGULATOR receiver
DDG61_RS17475	COG0706	membrane insertase activity
DDG61_RS17485	COG0778	Nitroreductase
DDG61_RS17495	COG0534	Mate efflux family protein
DDG61_RS17525	COG2207	Transcriptional regulator
DDG61_RS17535	COG1732	Glycine betaine
DDG61_RS17540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDG61_RS17550	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DDG61_RS17555	COG2226	methyltransferase
DDG61_RS17565	COG1473	amidohydrolase
DDG61_RS17570	COG1760	l-serine dehydratase
DDG61_RS17580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DDG61_RS17585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDG61_RS17590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDG61_RS17595	COG2171	N-acyltransferase activity
DDG61_RS17605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDG61_RS17615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DDG61_RS17620	COG3681	Belongs to the UPF0597 family
DDG61_RS17630	COG3829	transcription factor binding
DDG61_RS17635	COG2226	methyltransferase
DDG61_RS17660	COG5275	peptidyl-tyrosine sulfation
DDG61_RS17660	COG0252	asparaginase activity
DDG61_RS17665	COG0252	asparaginase activity
DDG61_RS17665	COG5275	peptidyl-tyrosine sulfation
DDG61_RS17680	COG5275	peptidyl-tyrosine sulfation
DDG61_RS17680	COG0252	asparaginase activity
DDG61_RS17700	COG4656	Part of a membrane complex involved in electron transport
DDG61_RS17710	COG0726	polysaccharide deacetylase
DDG61_RS17735	COG0285	dihydrofolate synthase activity
DDG61_RS17745	COG3279	Response regulator of the LytR AlgR family
DDG61_RS17750	COG0525	valine-tRNA ligase activity
DDG61_RS17760	COG0726	polysaccharide deacetylase
DDG61_RS17775	COG0704	Plays a role in the regulation of phosphate uptake
DDG61_RS17780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDG61_RS17785	COG0581	inorganic phosphate transmembrane transporter activity
DDG61_RS17790	COG0573	inorganic phosphate transmembrane transporter activity
DDG61_RS17800	COG1131	(ABC) transporter
DDG61_RS17825	COG0745	RESPONSE REGULATOR receiver
DDG61_RS17830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DDG61_RS17835	COG1164	Oligoendopeptidase f
DDG61_RS17840	COG1285	pathogenesis
DDG61_RS17865	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DDG61_RS17870	COG3716	PTS system mannose fructose sorbose family IID component
DDG61_RS17875	COG3715	PTS system
DDG61_RS17880	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS17880	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS17885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDG61_RS17885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDG61_RS17895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDG61_RS17910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDG61_RS17915	COG0166	Belongs to the GPI family
DDG61_RS17925	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DDG61_RS17940	COG3012	SEC-C Motif Domain Protein
DDG61_RS17940	COG1405	negative regulation of cell septum assembly
DDG61_RS17965	COG1459	type II secretion system
DDG61_RS17970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDG61_RS17985	COG2814	Major facilitator Superfamily
DDG61_RS17990	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DDG61_RS17995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DDG61_RS18005	COG2059	Chromate
DDG61_RS18010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDG61_RS18015	COG0740	serine-type endopeptidase activity
DDG61_RS18020	COG0544	peptidyl-prolyl cis-trans isomerase activity
DDG61_RS18035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDG61_RS18055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDG61_RS18055	COG0493	'glutamate synthase
DDG61_RS18065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DDG61_RS18075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DDG61_RS18125	COG0463	Glycosyl transferase, family 2
DDG61_RS18125	COG0457	Tetratricopeptide repeat
DDG61_RS18140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS18150	COG0778	Nitroreductase
DDG61_RS18155	COG1733	regulation of RNA biosynthetic process
DDG61_RS18160	COG0693	protein deglycase activity
DDG61_RS18165	COG1522	sequence-specific DNA binding
DDG61_RS18170	COG0488	(ABC) transporter
DDG61_RS18175	COG0745	RESPONSE REGULATOR receiver
DDG61_RS18195	COG4555	ABC transporter
DDG61_RS18200	COG2199	diguanylate cyclase activity
DDG61_RS18250	COG0205	6-phosphofructokinase activity
DDG61_RS18260	COG1481	regulation of sporulation
DDG61_RS18275	COG1660	Displays ATPase and GTPase activities
DDG61_RS18285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDG61_RS18290	COG2116	formate transmembrane transporter activity
DDG61_RS18295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDG61_RS18325	COG0322	excinuclease ABC activity
DDG61_RS18335	COG0556	nucleotide-excision repair
DDG61_RS18345	COG1653	transport
DDG61_RS18355	COG1175	transmembrane transport
DDG61_RS18360	COG3842	ATPase activity
DDG61_RS18380	COG1648	precorrin-2 dehydrogenase activity
DDG61_RS18380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DDG61_RS18385	COG0113	porphobilinogen synthase activity
DDG61_RS18395	COG0181	hydroxymethylbilane synthase activity
DDG61_RS18405	COG2099	Precorrin-6x reductase
DDG61_RS18435	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DDG61_RS18450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDG61_RS18460	COG1797	cobyrinic acid a,c-diamide synthase activity
DDG61_RS18465	COG1492	cobalamin metabolic process
DDG61_RS18475	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DDG61_RS18480	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
DDG61_RS18485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DDG61_RS18505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDG61_RS18520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS18525	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDG61_RS18530	COG1363	Peptidase, m42
DDG61_RS18535	COG3711	transcriptional antiterminator
DDG61_RS18540	COG0191	fructose-bisphosphate aldolase activity
DDG61_RS18545	COG2222	sugar isomerase
DDG61_RS18550	COG0673	inositol 2-dehydrogenase activity
DDG61_RS18560	COG2188	Transcriptional regulator
DDG61_RS18585	COG0793	Belongs to the peptidase S41A family
DDG61_RS18585	COG3409	Peptidoglycan-binding domain 1 protein
DDG61_RS18590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DDG61_RS18600	COG3949	Membrane
DDG61_RS18605	COG3958	Transketolase
DDG61_RS18610	COG3959	Transketolase, thiamine diphosphate binding domain
DDG61_RS18615	COG2337	Toxic component of a toxin-antitoxin (TA) module
DDG61_RS18635	COG0516	GMP reductase activity
DDG61_RS18635	COG0517	IMP dehydrogenase activity
DDG61_RS18640	COG0736	holo-[acyl-carrier-protein] synthase activity
DDG61_RS18645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DDG61_RS18650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDG61_RS18655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDG61_RS18660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDG61_RS18665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDG61_RS18670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDG61_RS18675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDG61_RS18705	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DDG61_RS18705	COG3608	succinylglutamate desuccinylase aspartoacylase
DDG61_RS18710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDG61_RS18715	COG0698	ribose 5-phosphate isomerase
DDG61_RS18720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DDG61_RS18725	COG0009	L-threonylcarbamoyladenylate synthase
DDG61_RS18735	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DDG61_RS18740	COG2890	protein-(glutamine-N5) methyltransferase activity
DDG61_RS18745	COG3872	metal-dependent enzyme
DDG61_RS18750	COG0254	rRNA binding
DDG61_RS18755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DDG61_RS18760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DDG61_RS18770	COG2208	phosphoserine phosphatase activity
DDG61_RS18775	COG0248	Ppx GppA phosphatase
DDG61_RS18795	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DDG61_RS18805	COG3956	TIGRFAM MazG family protein
DDG61_RS18810	COG2244	polysaccharide biosynthetic process
DDG61_RS18815	COG2002	toxin-antitoxin pair type II binding
DDG61_RS18820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DDG61_RS18825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DDG61_RS18830	COG0193	aminoacyl-tRNA hydrolase activity
DDG61_RS18880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DDG61_RS18895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DDG61_RS18900	COG2088	sporulation resulting in formation of a cellular spore
DDG61_RS18905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDG61_RS18910	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDG61_RS18920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDG61_RS18925	COG2195	Cleaves the N-terminal amino acid of tripeptides
DDG61_RS18935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDG61_RS18940	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DDG61_RS18945	COG1840	ABC-type Fe3 transport system, periplasmic component
DDG61_RS18950	COG1840	ABC-type Fe3 transport system, periplasmic component
DDG61_RS18960	COG3842	ATPase activity
DDG61_RS18965	COG0613	PHP domain protein
DDG61_RS18970	COG3454	Phosphonate metabolism
DDG61_RS18975	COG4778	phosphonate C-P lyase system protein PhnL
DDG61_RS18980	COG4107	phosphonate C-P lyase system protein PhnK
DDG61_RS18985	COG3627	carbon phosphorus lyase activity
DDG61_RS19005	COG0084	hydrolase, TatD family'
DDG61_RS19010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDG61_RS19010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDG61_RS19015	COG0700	Nucleoside recognition
DDG61_RS19025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DDG61_RS19030	COG1522	sequence-specific DNA binding
DDG61_RS19035	COG0617	tRNA 3'-terminal CCA addition
DDG61_RS19040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DDG61_RS19045	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DDG61_RS19050	COG1774	PSP1 C-terminal conserved region
DDG61_RS19055	COG0470	DNA polymerase III
DDG61_RS19060	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDG61_RS19065	COG1982	Orn Lys Arg decarboxylase major
DDG61_RS19070	COG2155	Conserved Protein
DDG61_RS19095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDG61_RS19100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDG61_RS19110	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DDG61_RS19120	COG3191	aminopeptidase activity
DDG61_RS19130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDG61_RS19145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDG61_RS19160	COG1802	Transcriptional regulator
DDG61_RS19165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDG61_RS19195	COG0653	protein targeting
DDG61_RS19225	COG2271	Major facilitator Superfamily
DDG61_RS19230	COG0626	cystathionine gamma-synthase activity
DDG61_RS19255	COG0564	pseudouridine synthase activity
DDG61_RS19260	COG4978	Transcriptional regulator
DDG61_RS19260	COG0789	Transcriptional regulator
DDG61_RS19270	COG1136	(ABC) transporter
DDG61_RS19270	COG0577	efflux transmembrane transporter activity
DDG61_RS19275	COG5002	protein histidine kinase activity
DDG61_RS19285	COG1695	Transcriptional regulator
DDG61_RS19310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDG61_RS19320	COG0284	orotidine-5'-phosphate decarboxylase activity
DDG61_RS19340	COG1410	methionine synthase
DDG61_RS19340	COG0646	methionine synthase
DDG61_RS19350	COG1854	S-ribosylhomocysteine lyase activity
DDG61_RS19365	COG1876	peptidase activity
DDG61_RS19370	COG0037	tRNA processing
DDG61_RS19375	COG1408	metallophosphoesterase
DDG61_RS19390	COG1141	Ferredoxin
DDG61_RS19395	COG3964	amidohydrolase
DDG61_RS19405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DDG61_RS19415	COG0346	lactoylglutathione lyase activity
DDG61_RS19420	COG0534	Mate efflux family protein
DDG61_RS19435	COG4978	Transcriptional regulator
DDG61_RS19435	COG0789	Transcriptional regulator
DDG61_RS19445	COG5504	Zn-dependent protease
DDG61_RS19455	COG0519	Catalyzes the synthesis of GMP from XMP
DDG61_RS19465	COG1357	PFAM Pentapeptide repeats (8 copies)
DDG61_RS19470	COG2824	Alkylphosphonate utilization operon protein PhnA
DDG61_RS19485	COG0352	thiamine-phosphate diphosphorylase activity
DDG61_RS19490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDG61_RS19495	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DDG61_RS19495	COG0517	IMP dehydrogenase activity
DDG61_RS19515	COG1335	isochorismatase
DDG61_RS19525	COG0789	Transcriptional regulator
DDG61_RS19555	COG0583	DNA-binding transcription factor activity
DDG61_RS19560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDG61_RS19560	COG1522	sequence-specific DNA binding
DDG61_RS19575	COG3964	amidohydrolase
DDG61_RS19585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS19590	COG2188	Transcriptional regulator
DDG61_RS19595	COG1447	Phosphotransferase system cellobiose-specific component IIA
DDG61_RS19600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS19605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DDG61_RS19610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DDG61_RS19615	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DDG61_RS19630	COG1484	DNA-dependent DNA replication
DDG61_RS19655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DDG61_RS19665	COG0305	Participates in initiation and elongation during chromosome replication
DDG61_RS19670	COG0359	binds to the 23S rRNA
DDG61_RS19675	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DDG61_RS19690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDG61_RS19695	COG0629	single-stranded DNA binding
DDG61_RS19700	COG0360	Binds together with S18 to 16S ribosomal RNA
DDG61_RS19705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS19720	COG0425	Belongs to the sulfur carrier protein TusA family
DDG61_RS19735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DDG61_RS19750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDG61_RS19755	COG0583	DNA-binding transcription factor activity
DDG61_RS19765	COG1104	cysteine desulfurase activity
DDG61_RS19770	COG1475	DNA binding
DDG61_RS19775	COG1192	Involved in chromosome partitioning
DDG61_RS19780	COG1475	DNA binding
DDG61_RS19785	COG0357	Ribosomal RNA small subunit methyltransferase G
DDG61_RS19790	COG0445	tRNA wobble uridine modification
DDG61_RS19795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DDG61_RS19800	COG1847	R3H domain protein
DDG61_RS19805	COG0706	membrane insertase activity
DDG61_RS19810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DDG61_RS19815	COG0594	ribonuclease P activity
DDG61_RS19820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DDG61_RS19830	COG1704	LemA family
DDG61_RS19845	COG0629	single-stranded DNA binding
DDG61_RS19985	COG0270	DNA (cytosine-5-)-methyltransferase activity
DDG61_RS20150	COG0582	viral genome integration into host DNA