locus-tag	class	description
DSM105001_RS00010	COG0592	DNA-directed DNA polymerase activity
DSM105001_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DSM105001_RS00025	COG0187	DNA topoisomerase II activity
DSM105001_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DSM105001_RS00045	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM105001_RS00055	COG1191	sigma factor activity
DSM105001_RS00105	COG1827	regulation of RNA biosynthetic process
DSM105001_RS00110	COG0668	transmembrane transport
DSM105001_RS00115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSM105001_RS00120	COG0590	tRNA wobble adenosine to inosine editing
DSM105001_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DSM105001_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DSM105001_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DSM105001_RS00155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM105001_RS00395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DSM105001_RS00400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSM105001_RS00405	COG4463	regulation of RNA biosynthetic process
DSM105001_RS00410	COG3880	PFAM UvrB UvrC protein
DSM105001_RS00415	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DSM105001_RS00420	COG0542	response to heat
DSM105001_RS00425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DSM105001_RS00430	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DSM105001_RS00435	COG4956	integral membrane protein (PIN domain superfamily)
DSM105001_RS00455	COG3507	Belongs to the glycosyl hydrolase 43 family
DSM105001_RS00465	COG2390	Transcriptional regulator
DSM105001_RS00470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DSM105001_RS00475	COG0022	dehydrogenase e1 component
DSM105001_RS00480	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSM105001_RS00485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM105001_RS00490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS00490	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS00500	COG3414	Phosphotransferase system galactitol-specific IIB component
DSM105001_RS00505	COG3775	system Galactitol-specific IIC component
DSM105001_RS00520	COG0095	Lipoate-protein ligase
DSM105001_RS00525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DSM105001_RS00530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DSM105001_RS00535	COG0442	prolyl-tRNA aminoacylation
DSM105001_RS00540	COG0442	prolyl-tRNA aminoacylation
DSM105001_RS00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM105001_RS00555	COG0215	cysteine-tRNA ligase activity
DSM105001_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM105001_RS00575	COG3688	RNA-binding protein containing a PIN domain
DSM105001_RS00585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSM105001_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DSM105001_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
DSM105001_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSM105001_RS00610	COG0081	regulation of translation
DSM105001_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DSM105001_RS00620	COG0222	ribosome binding
DSM105001_RS00630	COG0085	RNA polymerase activity
DSM105001_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSM105001_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DSM105001_RS00645	COG0049	tRNA binding
DSM105001_RS00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSM105001_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSM105001_RS00660	COG0051	transcription antitermination factor activity, RNA binding
DSM105001_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DSM105001_RS00670	COG0088	Forms part of the polypeptide exit tunnel
DSM105001_RS00675	COG0089	rRNA binding
DSM105001_RS00680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSM105001_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSM105001_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DSM105001_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DSM105001_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DSM105001_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
DSM105001_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSM105001_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DSM105001_RS00720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DSM105001_RS00725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSM105001_RS00730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DSM105001_RS00735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DSM105001_RS00740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSM105001_RS00745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DSM105001_RS00750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSM105001_RS00755	COG1841	ribosomal large subunit assembly
DSM105001_RS00760	COG0200	Binds to the 23S rRNA
DSM105001_RS00770	COG0563	adenylate kinase activity
DSM105001_RS00775	COG0024	Methionine aminopeptidase
DSM105001_RS00785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DSM105001_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DSM105001_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSM105001_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSM105001_RS00805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSM105001_RS00810	COG0202	RNA polymerase activity
DSM105001_RS00815	COG0203	ribosomal protein L17
DSM105001_RS00820	COG1122	ATPase activity
DSM105001_RS00825	COG1122	ATPase activity
DSM105001_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DSM105001_RS00835	COG0101	tRNA pseudouridine synthase activity
DSM105001_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSM105001_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DSM105001_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS01095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DSM105001_RS01105	COG0280	phosphate acetyltransferase
DSM105001_RS01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM105001_RS01145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSM105001_RS01150	COG2897	thiosulfate sulfurtransferase activity
DSM105001_RS01160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DSM105001_RS01165	COG2385	sporulation resulting in formation of a cellular spore
DSM105001_RS01175	COG1609	Transcriptional regulator
DSM105001_RS01180	COG1077	Cell shape determining protein MreB Mrl
DSM105001_RS01185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DSM105001_RS01195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DSM105001_RS01200	COG3949	Membrane
DSM105001_RS01205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DSM105001_RS01210	COG1040	competence protein
DSM105001_RS01215	COG3711	transcriptional antiterminator
DSM105001_RS01215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS01220	COG1447	Phosphotransferase system cellobiose-specific component IIA
DSM105001_RS01225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS01230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS01240	COG1446	asparaginase
DSM105001_RS01245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS01250	COG3142	Participates in the control of copper homeostasis
DSM105001_RS01255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DSM105001_RS01260	COG0653	protein targeting
DSM105001_RS01270	COG2183	response to ionizing radiation
DSM105001_RS01275	COG1228	amidohydrolase
DSM105001_RS01290	COG0802	atpase or kinase
DSM105001_RS01295	COG1214	PFAM Peptidase M22, glycoprotease
DSM105001_RS01300	COG0456	acetyltransferase
DSM105001_RS01305	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSM105001_RS01320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSM105001_RS01340	COG3279	Response regulator of the LytR AlgR family
DSM105001_RS01380	COG1473	amidohydrolase
DSM105001_RS01395	COG0534	Mate efflux family protein
DSM105001_RS01400	COG0488	(ABC) transporter
DSM105001_RS01405	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DSM105001_RS01415	COG2221	Nitrite and sulphite reductase 4Fe-4S
DSM105001_RS01425	COG1151	hydroxylamine reductase activity
DSM105001_RS01440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DSM105001_RS01470	COG0540	Belongs to the ATCase OTCase family
DSM105001_RS01475	COG0543	2 iron, 2 sulfur cluster binding
DSM105001_RS01480	COG0167	dihydroorotate dehydrogenase activity
DSM105001_RS01485	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSM105001_RS01495	COG0583	DNA-binding transcription factor activity
DSM105001_RS01510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM105001_RS01515	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DSM105001_RS01520	COG0459	protein refolding
DSM105001_RS01525	COG1691	(AIR) carboxylase
DSM105001_RS01530	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DSM105001_RS01535	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DSM105001_RS01540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSM105001_RS01540	COG0519	Catalyzes the synthesis of GMP from XMP
DSM105001_RS01565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSM105001_RS01570	COG2200	EAL domain
DSM105001_RS01570	COG2771	luxR family
DSM105001_RS01585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS01590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS01600	COG1011	Hydrolase
DSM105001_RS01625	COG0778	Nitroreductase
DSM105001_RS01630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DSM105001_RS01635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DSM105001_RS01640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSM105001_RS01645	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSM105001_RS01650	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DSM105001_RS01655	COG0138	bifunctional purine biosynthesis protein purh
DSM105001_RS01660	COG0151	Belongs to the GarS family
DSM105001_RS01665	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSM105001_RS01675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DSM105001_RS01690	COG0741	lytic transglycosylase activity
DSM105001_RS01725	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DSM105001_RS01730	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DSM105001_RS01745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DSM105001_RS01755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DSM105001_RS01765	COG0463	Glycosyl transferase, family 2
DSM105001_RS01800	COG4786	Flagellar basal body rod
DSM105001_RS01810	COG1677	Flagellar hook-basal body complex protein FliE
DSM105001_RS01815	COG1766	The M ring may be actively involved in energy transduction
DSM105001_RS01820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSM105001_RS01830	COG1157	protein secretion by the type III secretion system
DSM105001_RS01845	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DSM105001_RS01850	COG4786	Flagellar basal body rod
DSM105001_RS01860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSM105001_RS01865	COG1360	Flagellar Motor Protein
DSM105001_RS01880	COG1338	Plays a role in the flagellum-specific transport system
DSM105001_RS01890	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSM105001_RS01895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DSM105001_RS01900	COG1419	protein localization to endoplasmic reticulum
DSM105001_RS01910	COG1191	sigma factor activity
DSM105001_RS01925	COG4786	Flagellar basal body rod
DSM105001_RS01940	COG1776	CheC inhibitor of MCP methylation
DSM105001_RS01940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DSM105001_RS01955	COG1454	alcohol dehydrogenase
DSM105001_RS01960	COG1533	DNA photolyase activity
DSM105001_RS01975	COG1733	regulation of RNA biosynthetic process
DSM105001_RS01995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DSM105001_RS02000	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS02000	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS02005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS02005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS02030	COG3716	PTS system mannose fructose sorbose family IID component
DSM105001_RS02040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS02050	COG3620	sequence-specific DNA binding
DSM105001_RS02060	COG1131	(ABC) transporter
DSM105001_RS02080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DSM105001_RS02085	COG1609	Transcriptional regulator
DSM105001_RS02090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM105001_RS02095	COG1879	ABC-type sugar transport system periplasmic component
DSM105001_RS02100	COG1129	ABC transporter
DSM105001_RS02105	COG1172	Belongs to the binding-protein-dependent transport system permease family
DSM105001_RS02110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS02120	COG1473	amidohydrolase
DSM105001_RS02160	COG2217	Heavy metal translocating P-type atpase
DSM105001_RS02180	COG0586	Pfam SNARE associated Golgi protein
DSM105001_RS02200	COG2205	protein histidine kinase activity
DSM105001_RS02205	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS02240	COG1122	ATPase activity
DSM105001_RS02245	COG0210	DNA helicase
DSM105001_RS02250	COG1362	aminopeptidase activity
DSM105001_RS02260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DSM105001_RS02275	COG1454	alcohol dehydrogenase
DSM105001_RS02275	COG1012	belongs to the aldehyde dehydrogenase family
DSM105001_RS02285	COG1136	(ABC) transporter
DSM105001_RS02295	COG3290	protein histidine kinase activity
DSM105001_RS02325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM105001_RS02330	COG2357	RelA SpoT domain protein
DSM105001_RS02350	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DSM105001_RS02375	COG2190	(PTS) system
DSM105001_RS02375	COG1263	PTS System
DSM105001_RS02375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS02380	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS02385	COG3711	transcriptional antiterminator
DSM105001_RS02390	COG0367	asparagine synthase
DSM105001_RS02405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM105001_RS02430	COG1960	acyl-CoA dehydrogenase activity
DSM105001_RS02435	COG2086	electron transfer activity
DSM105001_RS02440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSM105001_RS02445	COG3829	transcription factor binding
DSM105001_RS02450	COG0191	fructose-bisphosphate aldolase activity
DSM105001_RS02460	COG1187	pseudouridine synthase activity
DSM105001_RS02490	COG1674	ftsk spoiiie
DSM105001_RS02495	COG2946	Replication initiation factor
DSM105001_RS02590	COG3620	sequence-specific DNA binding
DSM105001_RS02595	COG1131	(ABC) transporter
DSM105001_RS02640	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSM105001_RS02665	COG3829	transcription factor binding
DSM105001_RS02670	COG3804	dihydrodipicolinate reductase
DSM105001_RS02680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DSM105001_RS02690	COG5012	cobalamin binding
DSM105001_RS02700	COG3457	Alanine racemase
DSM105001_RS02705	COG1757	Na H antiporter
DSM105001_RS02725	COG3973	AAA domain
DSM105001_RS02735	COG1136	(ABC) transporter
DSM105001_RS02745	COG5002	protein histidine kinase activity
DSM105001_RS02750	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS02755	COG1309	transcriptional regulator
DSM105001_RS02765	COG1737	Transcriptional regulator
DSM105001_RS02775	COG0561	phosphatase activity
DSM105001_RS02780	COG0366	Alpha amylase catalytic
DSM105001_RS02785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS02785	COG2190	(PTS) system
DSM105001_RS02785	COG1263	PTS System
DSM105001_RS02800	COG0655	NAD(P)H dehydrogenase (quinone) activity
DSM105001_RS02830	COG1131	(ABC) transporter
DSM105001_RS02850	COG5002	protein histidine kinase activity
DSM105001_RS02855	COG0577	efflux transmembrane transporter activity
DSM105001_RS02855	COG1136	(ABC) transporter
DSM105001_RS02860	COG1136	(ABC) transporter
DSM105001_RS02865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DSM105001_RS02875	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS02880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSM105001_RS02895	COG1063	alcohol dehydrogenase
DSM105001_RS02905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS02915	COG3716	PTS system mannose fructose sorbose family IID component
DSM105001_RS02935	COG3279	Response regulator of the LytR AlgR family
DSM105001_RS02950	COG0535	radical SAM domain protein
DSM105001_RS02955	COG0641	radical SAM
DSM105001_RS02980	COG1136	(ABC) transporter
DSM105001_RS02990	COG1686	Belongs to the peptidase S11 family
DSM105001_RS02995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS02995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS03015	COG2205	protein histidine kinase activity
DSM105001_RS03040	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSM105001_RS03045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DSM105001_RS03070	COG2378	regulation of single-species biofilm formation
DSM105001_RS03080	COG2201	protein-glutamate methylesterase activity
DSM105001_RS03085	COG1776	CheC inhibitor of MCP methylation
DSM105001_RS03090	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DSM105001_RS03095	COG0835	chemotaxis
DSM105001_RS03105	COG0840	transmembrane signaling receptor activity
DSM105001_RS03110	COG0643	Histidine kinase
DSM105001_RS03110	COG2198	Histidine kinase
DSM105001_RS03115	COG0835	chemotaxis
DSM105001_RS03125	COG2201	protein-glutamate methylesterase activity
DSM105001_RS03175	COG2339	peptidase activity
DSM105001_RS03180	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DSM105001_RS03180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSM105001_RS03185	COG0681	Belongs to the peptidase S26 family
DSM105001_RS03200	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSM105001_RS03205	COG2066	Belongs to the glutaminase family
DSM105001_RS03215	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DSM105001_RS03230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSM105001_RS03235	COG1067	ATP-dependent peptidase activity
DSM105001_RS03240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSM105001_RS03245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DSM105001_RS03255	COG1744	ABC transporter substrate-binding protein PnrA-like
DSM105001_RS03280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSM105001_RS03320	COG1309	transcriptional regulator
DSM105001_RS03325	COG3848	Pyruvate phosphate dikinase
DSM105001_RS03325	COG0574	Belongs to the PEP-utilizing enzyme family
DSM105001_RS03335	COG3706	GGDEF domain
DSM105001_RS03395	COG3969	phosphoadenosine phosphosulfate
DSM105001_RS03400	COG1475	DNA binding
DSM105001_RS03415	COG3546	catalase activity
DSM105001_RS03420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DSM105001_RS03440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DSM105001_RS03475	COG3279	Response regulator of the LytR AlgR family
DSM105001_RS03480	COG0577	efflux transmembrane transporter activity
DSM105001_RS03485	COG1136	(ABC) transporter
DSM105001_RS03500	COG4978	Transcriptional regulator
DSM105001_RS03500	COG0789	Transcriptional regulator
DSM105001_RS03540	COG0305	Participates in initiation and elongation during chromosome replication
DSM105001_RS03560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DSM105001_RS03565	COG0534	Mate efflux family protein
DSM105001_RS03580	COG4335	DNA alkylation repair
DSM105001_RS03635	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS03640	COG2205	protein histidine kinase activity
DSM105001_RS03645	COG1131	(ABC) transporter
DSM105001_RS03660	COG1802	Transcriptional regulator
DSM105001_RS03665	COG1506	peptidase
DSM105001_RS03665	COG4946	Tricorn protease homolog
DSM105001_RS03665	COG0823	Involved in the tonB-independent uptake of proteins
DSM105001_RS03670	COG0823	Involved in the tonB-independent uptake of proteins
DSM105001_RS03670	COG4946	Tricorn protease homolog
DSM105001_RS03670	COG1506	peptidase
DSM105001_RS03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS03700	COG0038	chloride channel
DSM105001_RS03775	COG2205	protein histidine kinase activity
DSM105001_RS03810	COG1595	DNA-templated transcription, initiation
DSM105001_RS03825	COG2814	Major facilitator Superfamily
DSM105001_RS03830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSM105001_RS03835	COG1609	Transcriptional regulator
DSM105001_RS03850	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DSM105001_RS03855	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DSM105001_RS03890	COG0789	Transcriptional regulator
DSM105001_RS03910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DSM105001_RS03915	COG0569	domain protein
DSM105001_RS03920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DSM105001_RS03925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DSM105001_RS03930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM105001_RS03930	COG0072	phenylalanine-tRNA ligase activity
DSM105001_RS03945	COG0826	peptidase U32
DSM105001_RS03955	COG1051	belongs to the nudix hydrolase family
DSM105001_RS03965	COG3706	GGDEF domain
DSM105001_RS03970	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSM105001_RS03975	COG1193	negative regulation of DNA recombination
DSM105001_RS03980	COG1683	Conserved Protein
DSM105001_RS03985	COG0018	arginyl-trna synthetase
DSM105001_RS04000	COG1032	radical SAM domain protein
DSM105001_RS04010	COG0583	DNA-binding transcription factor activity
DSM105001_RS04015	COG0110	maltose O-acetyltransferase activity
DSM105001_RS04020	COG0280	phosphate acetyltransferase
DSM105001_RS04025	COG1151	hydroxylamine reductase activity
DSM105001_RS04035	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DSM105001_RS04040	COG3404	Formiminotransferase-cyclodeaminase
DSM105001_RS04045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSM105001_RS04055	COG0646	methionine synthase
DSM105001_RS04055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSM105001_RS04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM105001_RS04090	COG0509	glycine decarboxylation via glycine cleavage system
DSM105001_RS04110	COG0095	Lipoate-protein ligase
DSM105001_RS04130	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DSM105001_RS04145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM105001_RS04145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSM105001_RS04155	COG3192	ethanolamine utilization protein
DSM105001_RS04160	COG1349	DNA-binding transcription factor activity
DSM105001_RS04170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DSM105001_RS04175	COG1360	Flagellar Motor Protein
DSM105001_RS04195	COG0210	DNA helicase
DSM105001_RS04200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM105001_RS04205	COG0765	amino acid transport
DSM105001_RS04210	COG1126	abc transporter atp-binding protein
DSM105001_RS04220	COG0301	tRNA thio-modification
DSM105001_RS04230	COG0778	Nitroreductase
DSM105001_RS04235	COG5001	Diguanylate cyclase
DSM105001_RS04235	COG3300	MHYT domain
DSM105001_RS04240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSM105001_RS04250	COG0530	calcium, potassium:sodium antiporter activity
DSM105001_RS04255	COG0513	Belongs to the DEAD box helicase family
DSM105001_RS04275	COG3732	PTS system glucitol sorbitol-specific
DSM105001_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
DSM105001_RS04295	COG0243	molybdopterin cofactor binding
DSM105001_RS04300	COG1366	Belongs to the anti-sigma-factor antagonist family
DSM105001_RS04305	COG2172	sigma factor antagonist activity
DSM105001_RS04310	COG1191	sigma factor activity
DSM105001_RS04320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSM105001_RS04345	COG1473	amidohydrolase
DSM105001_RS04355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DSM105001_RS04365	COG0750	zinc metalloprotease
DSM105001_RS04370	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS04375	COG0488	(ABC) transporter
DSM105001_RS04390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSM105001_RS04405	COG1739	Uncharacterized protein family UPF0029
DSM105001_RS04415	COG0730	response to heat
DSM105001_RS04420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSM105001_RS04425	COG0217	transcriptional regulatory protein
DSM105001_RS04430	COG1609	Transcriptional regulator
DSM105001_RS04435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM105001_RS04450	COG1024	Enoyl-CoA hydratase
DSM105001_RS04455	COG2610	gluconate transmembrane transporter activity
DSM105001_RS04470	COG2086	electron transfer activity
DSM105001_RS04475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSM105001_RS04515	COG2186	Transcriptional regulator
DSM105001_RS04520	COG2814	Major facilitator Superfamily
DSM105001_RS04525	COG1263	PTS System
DSM105001_RS04525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS04525	COG2190	(PTS) system
DSM105001_RS04530	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS04540	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS04545	COG2205	protein histidine kinase activity
DSM105001_RS04565	COG1592	Rubrerythrin
DSM105001_RS04575	COG2033	superoxide reductase activity
DSM105001_RS04580	COG0069	glutamate synthase activity
DSM105001_RS04600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM105001_RS04610	COG0473	3-isopropylmalate dehydrogenase activity
DSM105001_RS04615	COG1846	Transcriptional regulator
DSM105001_RS04640	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSM105001_RS04645	COG0138	bifunctional purine biosynthesis protein purh
DSM105001_RS04655	COG0438	transferase activity, transferring glycosyl groups
DSM105001_RS04655	COG0297	glycogen (starch) synthase activity
DSM105001_RS04685	COG1473	amidohydrolase
DSM105001_RS04690	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DSM105001_RS04705	COG0601	transmembrane transport
DSM105001_RS04710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM105001_RS04720	COG0444	Belongs to the ABC transporter superfamily
DSM105001_RS04725	COG4608	Belongs to the ABC transporter superfamily
DSM105001_RS04730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS04730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS04745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS04755	COG1486	melibiose metabolic process
DSM105001_RS04765	COG1073	alpha beta
DSM105001_RS04775	COG1910	domain protein
DSM105001_RS04780	COG0725	ABC transporter, periplasmic molybdate-binding protein
DSM105001_RS04785	COG4149	molybdate abc transporter
DSM105001_RS04790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSM105001_RS04795	COG0110	maltose O-acetyltransferase activity
DSM105001_RS04805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DSM105001_RS04810	COG4120	Belongs to the binding-protein-dependent transport system permease family
DSM105001_RS04815	COG2984	ABC transporter substrate binding protein
DSM105001_RS04825	COG4120	Belongs to the binding-protein-dependent transport system permease family
DSM105001_RS04830	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSM105001_RS04830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSM105001_RS04845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DSM105001_RS04850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DSM105001_RS04855	COG0297	glycogen (starch) synthase activity
DSM105001_RS04860	COG0058	SHG alpha-glucan phosphorylase activity
DSM105001_RS04870	COG1802	Transcriptional regulator
DSM105001_RS04875	COG1982	Orn Lys Arg decarboxylase major
DSM105001_RS04880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DSM105001_RS04885	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DSM105001_RS04890	COG0010	Belongs to the arginase family
DSM105001_RS04925	COG4868	Belongs to the UPF0371 family
DSM105001_RS04930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSM105001_RS04940	COG1174	glycine betaine transport
DSM105001_RS04945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSM105001_RS04975	COG0534	Mate efflux family protein
DSM105001_RS04980	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSM105001_RS04980	COG0539	negative regulation of cytoplasmic translation
DSM105001_RS04985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DSM105001_RS04995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSM105001_RS05000	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSM105001_RS05005	COG0066	3-isopropylmalate dehydratase activity
DSM105001_RS05010	COG0473	3-isopropylmalate dehydrogenase activity
DSM105001_RS05025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSM105001_RS05035	COG5002	protein histidine kinase activity
DSM105001_RS05035	COG5001	Diguanylate cyclase
DSM105001_RS05035	COG3447	MASE1 domain protein
DSM105001_RS05060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DSM105001_RS05065	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DSM105001_RS05075	COG0281	malic enzyme
DSM105001_RS05100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DSM105001_RS05105	COG0363	glucosamine-6-phosphate deaminase activity
DSM105001_RS05120	COG5002	protein histidine kinase activity
DSM105001_RS05125	COG5001	Diguanylate cyclase
DSM105001_RS05130	COG4978	Transcriptional regulator
DSM105001_RS05130	COG0789	Transcriptional regulator
DSM105001_RS05140	COG1132	(ABC) transporter
DSM105001_RS05160	COG2364	Membrane
DSM105001_RS05170	COG3842	ATPase activity
DSM105001_RS05175	COG1176	ABC-type spermidine putrescine transport system, permease component I
DSM105001_RS05180	COG1177	transmembrane transport
DSM105001_RS05185	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DSM105001_RS05195	COG5298	Protein conserved in bacteria
DSM105001_RS05200	COG1215	transferase activity, transferring glycosyl groups
DSM105001_RS05215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DSM105001_RS05245	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS05250	COG2247	cell wall binding repeat
DSM105001_RS05250	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS05260	COG0210	DNA helicase
DSM105001_RS05270	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DSM105001_RS05275	COG1074	ATP-dependent DNA helicase activity
DSM105001_RS05280	COG0420	3'-5' exonuclease activity
DSM105001_RS05285	COG0419	ATPase involved in DNA repair
DSM105001_RS05290	COG4536	flavin adenine dinucleotide binding
DSM105001_RS05300	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSM105001_RS05310	COG0622	Phosphoesterase
DSM105001_RS05315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSM105001_RS05320	COG1131	(ABC) transporter
DSM105001_RS05335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DSM105001_RS05340	COG1960	acyl-CoA dehydrogenase activity
DSM105001_RS05345	COG2086	electron transfer activity
DSM105001_RS05350	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSM105001_RS05365	COG0183	Belongs to the thiolase family
DSM105001_RS05370	COG0564	pseudouridine synthase activity
DSM105001_RS05380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSM105001_RS05435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DSM105001_RS05440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS05445	COG4224	UPF0291 protein
DSM105001_RS05450	COG1362	aminopeptidase activity
DSM105001_RS05455	COG2188	Transcriptional regulator
DSM105001_RS05480	COG1396	sequence-specific DNA binding
DSM105001_RS05490	COG3645	SOS response
DSM105001_RS05490	COG3646	Phage regulatory protein
DSM105001_RS05510	COG3617	BRO family, N-terminal domain
DSM105001_RS05520	COG1476	TRANSCRIPTIONal
DSM105001_RS05605	COG0270	DNA (cytosine-5-)-methyltransferase activity
DSM105001_RS05625	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DSM105001_RS05630	COG3561	AntA/AntB antirepressor
DSM105001_RS05650	COG5484	DNA packaging
DSM105001_RS05760	COG3617	BRO family, N-terminal domain
DSM105001_RS05900	COG3715	PTS system
DSM105001_RS05905	COG3716	PTS system mannose fructose sorbose family IID component
DSM105001_RS05910	COG0583	DNA-binding transcription factor activity
DSM105001_RS05930	COG3414	Phosphotransferase system galactitol-specific IIB component
DSM105001_RS05935	COG1132	(ABC) transporter
DSM105001_RS05945	COG1473	amidohydrolase
DSM105001_RS05960	COG3279	Response regulator of the LytR AlgR family
DSM105001_RS05975	COG1882	Formate acetyltransferase
DSM105001_RS05980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DSM105001_RS05985	COG1396	sequence-specific DNA binding
DSM105001_RS06010	COG3708	Transcriptional regulator
DSM105001_RS06010	COG2207	Transcriptional regulator
DSM105001_RS06030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM105001_RS06030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSM105001_RS06035	COG0237	dephospho-CoA kinase activity
DSM105001_RS06060	COG0346	lactoylglutathione lyase activity
DSM105001_RS06065	COG0791	NLP P60 protein
DSM105001_RS06075	COG4656	Part of a membrane complex involved in electron transport
DSM105001_RS06080	COG4658	electron transport chain
DSM105001_RS06085	COG4659	FMN binding
DSM105001_RS06090	COG4660	Part of a membrane complex involved in electron transport
DSM105001_RS06095	COG4657	Part of a membrane complex involved in electron transport
DSM105001_RS06100	COG1245	4Fe-4S binding domain
DSM105001_RS06100	COG2878	Part of a membrane complex involved in electron transport
DSM105001_RS06105	COG0424	maF-like protein
DSM105001_RS06110	COG2003	Belongs to the UPF0758 family
DSM105001_RS06115	COG1077	Cell shape determining protein MreB Mrl
DSM105001_RS06135	COG0850	regulation of cytokinetic process
DSM105001_RS06140	COG2894	cell division
DSM105001_RS06145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DSM105001_RS06150	COG0772	Belongs to the SEDS family
DSM105001_RS06155	COG1803	Methylglyoxal synthase
DSM105001_RS06160	COG1695	Transcriptional regulator
DSM105001_RS06175	COG0426	domain, Protein
DSM105001_RS06195	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DSM105001_RS06205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DSM105001_RS06210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSM105001_RS06220	COG0460	homoserine dehydrogenase
DSM105001_RS06230	COG3314	Sporulation integral membrane protein YlbJ
DSM105001_RS06235	COG2186	Transcriptional regulator
DSM105001_RS06240	COG3875	lactate racemase activity
DSM105001_RS06245	COG2086	electron transfer activity
DSM105001_RS06250	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSM105001_RS06255	COG0277	FAD linked oxidase domain protein
DSM105001_RS06260	COG1323	Belongs to the UPF0348 family
DSM105001_RS06265	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DSM105001_RS06275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DSM105001_RS06285	COG0416	fatty acid biosynthetic process
DSM105001_RS06290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DSM105001_RS06300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DSM105001_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
DSM105001_RS06310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSM105001_RS06315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DSM105001_RS06320	COG3706	GGDEF domain
DSM105001_RS06335	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSM105001_RS06350	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DSM105001_RS06355	COG3854	ATPases associated with a variety of cellular activities
DSM105001_RS06395	COG1302	Protein conserved in bacteria
DSM105001_RS06400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM105001_RS06405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSM105001_RS06410	COG1570	exodeoxyribonuclease VII activity
DSM105001_RS06425	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DSM105001_RS06430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DSM105001_RS06435	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DSM105001_RS06440	COG0497	DNA recombination
DSM105001_RS06450	COG0456	acetyltransferase
DSM105001_RS06455	COG0456	acetyltransferase
DSM105001_RS06460	COG0750	zinc metalloprotease
DSM105001_RS06480	COG0463	Glycosyl transferase, family 2
DSM105001_RS06495	COG0494	nUDIX hydrolase
DSM105001_RS06505	COG4974	Belongs to the 'phage' integrase family
DSM105001_RS06510	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DSM105001_RS06515	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DSM105001_RS06525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DSM105001_RS06530	COG4122	O-methyltransferase activity
DSM105001_RS06535	COG0826	peptidase U32
DSM105001_RS06540	COG0768	penicillin binding
DSM105001_RS06570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DSM105001_RS06580	COG0571	ribonuclease III activity
DSM105001_RS06590	COG1196	nuclear chromosome segregation
DSM105001_RS06595	COG0552	protein localization to endoplasmic reticulum
DSM105001_RS06605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSM105001_RS06610	COG0228	four-way junction DNA binding
DSM105001_RS06620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DSM105001_RS06625	COG0336	Belongs to the RNA methyltransferase TrmD family
DSM105001_RS06630	COG0335	large ribosomal subunit rRNA binding
DSM105001_RS06640	COG1114	Component of the transport system for branched-chain amino acids
DSM105001_RS06655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSM105001_RS06685	COG1131	(ABC) transporter
DSM105001_RS06690	COG2197	response regulator
DSM105001_RS06695	COG4585	Histidine kinase
DSM105001_RS06700	COG0792	nuclease activity
DSM105001_RS06705	COG0606	chelatase, subunit chli
DSM105001_RS06710	COG0758	DNA mediated transformation
DSM105001_RS06715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSM105001_RS06725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DSM105001_RS06735	COG1959	2 iron, 2 sulfur cluster binding
DSM105001_RS06745	COG0822	iron-sulfur transferase activity
DSM105001_RS06750	COG0482	sulfurtransferase activity
DSM105001_RS06755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSM105001_RS06760	COG4472	Bacterial protein of unknown function (DUF965)
DSM105001_RS06770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DSM105001_RS06775	COG3906	Belongs to the UPF0473 family
DSM105001_RS06780	COG0735	belongs to the Fur family
DSM105001_RS06790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DSM105001_RS06800	COG1686	Belongs to the peptidase S11 family
DSM105001_RS06810	COG2207	Transcriptional regulator
DSM105001_RS06810	COG1917	Cupin 2, conserved barrel domain protein
DSM105001_RS06815	COG1994	Peptidase M50
DSM105001_RS06825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DSM105001_RS06880	COG0779	Required for maturation of 30S ribosomal subunits
DSM105001_RS06885	COG0195	Participates in both transcription termination and antitermination
DSM105001_RS06890	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DSM105001_RS06900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSM105001_RS06925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSM105001_RS06930	COG0196	riboflavin kinase activity
DSM105001_RS06935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DSM105001_RS06940	COG1307	EDD domain protein, DegV family
DSM105001_RS06945	COG1185	polyribonucleotide nucleotidyltransferase activity
DSM105001_RS06950	COG0726	polysaccharide deacetylase
DSM105001_RS06955	COG0612	Peptidase, M16
DSM105001_RS06960	COG1873	PFAM PRC-barrel domain
DSM105001_RS06965	COG0527	aspartate kinase activity
DSM105001_RS06970	COG0740	serine-type endopeptidase activity
DSM105001_RS06980	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DSM105001_RS06985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM105001_RS06995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DSM105001_RS07000	COG1418	mRNA catabolic process
DSM105001_RS07015	COG1968	undecaprenyl-diphosphatase activity
DSM105001_RS07025	COG0114	fumarate hydratase activity
DSM105001_RS07035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS07035	COG1263	PTS System
DSM105001_RS07045	COG1486	melibiose metabolic process
DSM105001_RS07050	COG0436	Aminotransferase
DSM105001_RS07060	COG0708	Exodeoxyribonuclease III
DSM105001_RS07075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM105001_RS07100	COG1131	(ABC) transporter
DSM105001_RS07130	COG1278	Cold shock
DSM105001_RS07140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM105001_RS07215	COG3299	homolog of phage Mu protein gp47
DSM105001_RS07220	COG3778	Protein conserved in bacteria
DSM105001_RS07265	COG1396	sequence-specific DNA binding
DSM105001_RS07270	COG2814	Major facilitator Superfamily
DSM105001_RS07280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DSM105001_RS07285	COG0471	metal ion transport
DSM105001_RS07285	COG3273	potassium ion transport
DSM105001_RS07290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DSM105001_RS07295	COG1914	H( )-stimulated, divalent metal cation uptake system
DSM105001_RS07300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DSM105001_RS07305	COG1984	allophanate hydrolase subunit 2
DSM105001_RS07310	COG1396	sequence-specific DNA binding
DSM105001_RS07315	COG4948	Mandelate Racemase Muconate Lactonizing
DSM105001_RS07360	COG1473	amidohydrolase
DSM105001_RS07365	COG1619	proteins homologs of microcin C7 resistance protein MccF
DSM105001_RS07380	COG0584	glycerophosphoryl diester phosphodiesterase
DSM105001_RS07400	COG0488	(ABC) transporter
DSM105001_RS07410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS07415	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSM105001_RS07420	COG1546	Belongs to the CinA family
DSM105001_RS07420	COG1058	Belongs to the CinA family
DSM105001_RS07435	COG3829	transcription factor binding
DSM105001_RS07445	COG1242	4 iron, 4 sulfur cluster binding
DSM105001_RS07485	COG5001	Diguanylate cyclase
DSM105001_RS07485	COG5002	protein histidine kinase activity
DSM105001_RS07485	COG3447	MASE1 domain protein
DSM105001_RS07490	COG2199	diguanylate cyclase activity
DSM105001_RS07490	COG2203	Gaf domain
DSM105001_RS07500	COG4978	Transcriptional regulator
DSM105001_RS07500	COG0789	Transcriptional regulator
DSM105001_RS07515	COG1285	pathogenesis
DSM105001_RS07520	COG1335	isochorismatase
DSM105001_RS07535	COG0726	polysaccharide deacetylase
DSM105001_RS07550	COG0450	alkyl hydroperoxide reductase
DSM105001_RS07565	COG2720	vancomycin resistance protein
DSM105001_RS07570	COG3829	transcription factor binding
DSM105001_RS07585	COG1346	cytolysis
DSM105001_RS07590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSM105001_RS07600	COG2340	Cysteine-rich secretory protein family
DSM105001_RS07605	COG0726	polysaccharide deacetylase
DSM105001_RS07610	COG0512	Glutamine amidotransferase of anthranilate synthase
DSM105001_RS07615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DSM105001_RS07620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSM105001_RS07630	COG0302	gtp cyclohydrolase
DSM105001_RS07635	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSM105001_RS07640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DSM105001_RS07645	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DSM105001_RS07650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DSM105001_RS07655	COG0358	DNA primase activity
DSM105001_RS07660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DSM105001_RS07665	COG2384	SAM-dependent methyltransferase
DSM105001_RS07670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DSM105001_RS07675	COG0655	NAD(P)H dehydrogenase (quinone) activity
DSM105001_RS07695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS07710	COG5002	protein histidine kinase activity
DSM105001_RS07710	COG3850	Histidine kinase
DSM105001_RS07715	COG1136	(ABC) transporter
DSM105001_RS07715	COG0577	efflux transmembrane transporter activity
DSM105001_RS07745	COG1132	(ABC) transporter
DSM105001_RS07750	COG1132	(ABC) transporter
DSM105001_RS07755	COG1773	rubredoxin
DSM105001_RS07755	COG1592	Rubrerythrin
DSM105001_RS07760	COG0412	Dienelactone hydrolase
DSM105001_RS07795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM105001_RS07830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DSM105001_RS07835	COG2011	ABC-type metal ion transport system permease component
DSM105001_RS07845	COG5002	protein histidine kinase activity
DSM105001_RS07850	COG2094	Belongs to the DNA glycosylase MPG family
DSM105001_RS07855	COG1396	sequence-specific DNA binding
DSM105001_RS07860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DSM105001_RS07865	COG4086	secreted protein
DSM105001_RS07880	COG0728	peptidoglycan biosynthetic process
DSM105001_RS07895	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DSM105001_RS07905	COG1131	(ABC) transporter
DSM105001_RS07915	COG0534	Mate efflux family protein
DSM105001_RS07930	COG0348	domain, Protein
DSM105001_RS07930	COG3901	Regulator of nitric oxide reductase transcription
DSM105001_RS07955	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DSM105001_RS07960	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSM105001_RS07970	COG5001	Diguanylate cyclase
DSM105001_RS07980	COG4978	Transcriptional regulator
DSM105001_RS07980	COG0789	Transcriptional regulator
DSM105001_RS07985	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DSM105001_RS08005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DSM105001_RS08010	COG0726	polysaccharide deacetylase
DSM105001_RS08020	COG1773	rubredoxin
DSM105001_RS08020	COG1592	Rubrerythrin
DSM105001_RS08025	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSM105001_RS08030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DSM105001_RS08035	COG0577	efflux transmembrane transporter activity
DSM105001_RS08040	COG0577	efflux transmembrane transporter activity
DSM105001_RS08040	COG1136	(ABC) transporter
DSM105001_RS08050	COG2205	protein histidine kinase activity
DSM105001_RS08055	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS08060	COG1136	(ABC) transporter
DSM105001_RS08065	COG0577	efflux transmembrane transporter activity
DSM105001_RS08070	COG0405	Gamma-glutamyltransferase
DSM105001_RS08085	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSM105001_RS08085	COG0493	'glutamate synthase
DSM105001_RS08095	COG1136	(ABC) transporter
DSM105001_RS08100	COG0577	efflux transmembrane transporter activity
DSM105001_RS08140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DSM105001_RS08145	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DSM105001_RS08150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM105001_RS08155	COG0131	Imidazoleglycerol-phosphate dehydratase
DSM105001_RS08160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DSM105001_RS08165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DSM105001_RS08170	COG0107	imidazoleglycerol-phosphate synthase activity
DSM105001_RS08175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DSM105001_RS08175	COG0140	phosphoribosyl-ATP diphosphatase activity
DSM105001_RS08180	COG0531	amino acid
DSM105001_RS08195	COG1595	DNA-templated transcription, initiation
DSM105001_RS08210	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DSM105001_RS08225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DSM105001_RS08230	COG0028	Belongs to the TPP enzyme family
DSM105001_RS08235	COG0582	viral genome integration into host DNA
DSM105001_RS08250	COG3620	sequence-specific DNA binding
DSM105001_RS08255	COG1396	sequence-specific DNA binding
DSM105001_RS08285	COG1396	sequence-specific DNA binding
DSM105001_RS08295	COG3646	Phage regulatory protein
DSM105001_RS08295	COG3645	SOS response
DSM105001_RS08345	COG0629	single-stranded DNA binding
DSM105001_RS08395	COG5484	DNA packaging
DSM105001_RS08405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM105001_RS08535	COG4193	domain, Protein
DSM105001_RS08545	COG3628	GPW Gp25 family protein
DSM105001_RS08550	COG3299	homolog of phage Mu protein gp47
DSM105001_RS08600	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS08600	COG1388	LysM domain
DSM105001_RS08620	COG3546	catalase activity
DSM105001_RS08625	COG1331	Highly conserved protein containing a thioredoxin domain
DSM105001_RS08635	COG2267	carboxylic ester hydrolase activity
DSM105001_RS08650	COG3584	3D domain protein
DSM105001_RS08650	COG1388	LysM domain
DSM105001_RS08660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM105001_RS08665	COG1295	ribonuclease BN
DSM105001_RS08670	COG5002	protein histidine kinase activity
DSM105001_RS08675	COG0460	homoserine dehydrogenase
DSM105001_RS08685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DSM105001_RS08690	COG2267	carboxylic ester hydrolase activity
DSM105001_RS08695	COG5566	PFAM Mor transcription activator
DSM105001_RS08705	COG2971	BadF BadG BcrA BcrD
DSM105001_RS08715	COG1129	ABC transporter
DSM105001_RS08720	COG1172	Belongs to the binding-protein-dependent transport system permease family
DSM105001_RS08730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSM105001_RS08740	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DSM105001_RS08745	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DSM105001_RS08750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DSM105001_RS08755	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DSM105001_RS08760	COG1045	serine acetyltransferase
DSM105001_RS08765	COG1141	Ferredoxin
DSM105001_RS08785	COG0351	phosphomethylpyrimidine kinase
DSM105001_RS08790	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DSM105001_RS08795	COG0352	thiamine-phosphate diphosphorylase activity
DSM105001_RS08800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS08820	COG1725	Transcriptional regulator
DSM105001_RS08850	COG0402	S-adenosylhomocysteine deaminase activity
DSM105001_RS08860	COG4555	ABC transporter
DSM105001_RS08865	COG1668	transmembrane transport
DSM105001_RS08870	COG5001	Diguanylate cyclase
DSM105001_RS08870	COG3300	MHYT domain
DSM105001_RS08875	COG1725	Transcriptional regulator
DSM105001_RS08880	COG1131	(ABC) transporter
DSM105001_RS08895	COG0668	transmembrane transport
DSM105001_RS08905	COG0426	domain, Protein
DSM105001_RS08920	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSM105001_RS08925	COG1876	peptidase activity
DSM105001_RS08950	COG0367	asparagine synthase
DSM105001_RS08955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM105001_RS08970	COG2310	stress, protein
DSM105001_RS08985	COG3853	Toxic anion resistance protein (TelA)
DSM105001_RS09015	COG5505	Protein of unknown function (DUF819)
DSM105001_RS09025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSM105001_RS09030	COG4605	iron ion homeostasis
DSM105001_RS09035	COG4604	ABC transporter, ATP-binding protein
DSM105001_RS09040	COG4607	ABC-type enterochelin transport system periplasmic component
DSM105001_RS09045	COG3706	GGDEF domain
DSM105001_RS09045	COG2203	Gaf domain
DSM105001_RS09045	COG5001	Diguanylate cyclase
DSM105001_RS09045	COG4251	negative regulation of phosphorylation
DSM105001_RS09060	COG0095	Lipoate-protein ligase
DSM105001_RS09065	COG1757	Na H antiporter
DSM105001_RS09080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSM105001_RS09085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSM105001_RS09090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSM105001_RS09095	COG3123	guanosine phosphorylase activity
DSM105001_RS09115	COG0402	S-adenosylhomocysteine deaminase activity
DSM105001_RS09125	COG1396	sequence-specific DNA binding
DSM105001_RS09135	COG0584	glycerophosphoryl diester phosphodiesterase
DSM105001_RS09155	COG1131	(ABC) transporter
DSM105001_RS09165	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS09170	COG2205	protein histidine kinase activity
DSM105001_RS09185	COG1733	regulation of RNA biosynthetic process
DSM105001_RS09190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DSM105001_RS09215	COG1309	transcriptional regulator
DSM105001_RS09250	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS09255	COG5002	protein histidine kinase activity
DSM105001_RS09260	COG3118	belongs to the thioredoxin family
DSM105001_RS09290	COG1115	amino acid carrier protein
DSM105001_RS09300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS09300	COG1263	PTS System
DSM105001_RS09300	COG2190	(PTS) system
DSM105001_RS09305	COG0363	glucosamine-6-phosphate deaminase activity
DSM105001_RS09310	COG0436	Aminotransferase
DSM105001_RS09335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM105001_RS09335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSM105001_RS09350	COG0514	ATP-dependent DNA helicase (RecQ)
DSM105001_RS09355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSM105001_RS09370	COG2022	thiamine diphosphate biosynthetic process
DSM105001_RS09375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DSM105001_RS09385	COG1288	antiporter activity
DSM105001_RS09405	COG0393	Putative heavy-metal-binding
DSM105001_RS09410	COG0521	Mo-molybdopterin cofactor biosynthetic process
DSM105001_RS09420	COG0315	cyclic pyranopterin monophosphate synthase activity
DSM105001_RS09500	COG1283	sodium-dependent phosphate transmembrane transporter activity
DSM105001_RS09525	COG5012	cobalamin binding
DSM105001_RS09530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DSM105001_RS09540	COG1011	Hydrolase
DSM105001_RS09545	COG1396	sequence-specific DNA binding
DSM105001_RS09545	COG1917	Cupin 2, conserved barrel domain protein
DSM105001_RS09550	COG2610	gluconate transmembrane transporter activity
DSM105001_RS09555	COG5002	protein histidine kinase activity
DSM105001_RS09560	COG2204	response regulator
DSM105001_RS09600	COG0786	glutamate:sodium symporter activity
DSM105001_RS09615	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DSM105001_RS09620	COG1924	4 iron, 4 sulfur cluster binding
DSM105001_RS09625	COG2247	cell wall binding repeat
DSM105001_RS09625	COG2385	sporulation resulting in formation of a cellular spore
DSM105001_RS09635	COG1309	transcriptional regulator
DSM105001_RS09660	COG0242	peptide deformylase activity
DSM105001_RS09695	COG3326	Membrane
DSM105001_RS09705	COG0494	nUDIX hydrolase
DSM105001_RS09750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM105001_RS09755	COG0765	amino acid transport
DSM105001_RS09765	COG1393	Belongs to the ArsC family
DSM105001_RS09775	COG1606	tRNA processing
DSM105001_RS09780	COG0116	Belongs to the methyltransferase superfamily
DSM105001_RS09795	COG3850	Histidine kinase
DSM105001_RS09795	COG5002	protein histidine kinase activity
DSM105001_RS09805	COG0137	argininosuccinate synthase activity
DSM105001_RS09815	COG0789	Transcriptional regulator
DSM105001_RS09825	COG2323	membrane
DSM105001_RS09840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSM105001_RS09865	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSM105001_RS09870	COG0583	DNA-binding transcription factor activity
DSM105001_RS09885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSM105001_RS09900	COG1609	Transcriptional regulator
DSM105001_RS09910	COG1621	beta-fructofuranosidase activity
DSM105001_RS09915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM105001_RS09930	COG2814	Major facilitator Superfamily
DSM105001_RS09960	COG0406	alpha-ribazole phosphatase activity
DSM105001_RS09965	COG2081	HI0933 family
DSM105001_RS09970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DSM105001_RS09975	COG0204	Acyl-transferase
DSM105001_RS09980	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DSM105001_RS10000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DSM105001_RS10005	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSM105001_RS10010	COG3022	response to hydroperoxide
DSM105001_RS10025	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DSM105001_RS10030	COG1846	Transcriptional regulator
DSM105001_RS10035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM105001_RS10040	COG2205	protein histidine kinase activity
DSM105001_RS10050	COG0598	Magnesium transport protein CorA
DSM105001_RS10060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DSM105001_RS10065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DSM105001_RS10070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSM105001_RS10075	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSM105001_RS10080	COG0077	Prephenate dehydratase
DSM105001_RS10080	COG1605	Chorismate mutase
DSM105001_RS10085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSM105001_RS10095	COG0287	Prephenate dehydrogenase
DSM105001_RS10105	COG3706	GGDEF domain
DSM105001_RS10130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM105001_RS10135	COG2226	methyltransferase
DSM105001_RS10140	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DSM105001_RS10170	COG2131	deaminase
DSM105001_RS10210	COG1720	tRNA m6t6A37 methyltransferase activity
DSM105001_RS10220	COG3708	Transcriptional regulator
DSM105001_RS10220	COG2207	Transcriptional regulator
DSM105001_RS10325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM105001_RS10370	COG4303	Ethanolamine ammonia lyase large subunit
DSM105001_RS10375	COG4302	ethanolamine ammonia-lyase activity
DSM105001_RS10390	COG1454	alcohol dehydrogenase
DSM105001_RS10390	COG1012	belongs to the aldehyde dehydrogenase family
DSM105001_RS10405	COG4869	propanediol catabolic process
DSM105001_RS10415	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
DSM105001_RS10425	COG3192	ethanolamine utilization protein
DSM105001_RS10430	COG4766	ethanolamine catabolic process
DSM105001_RS10440	COG1473	amidohydrolase
DSM105001_RS10445	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DSM105001_RS10450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSM105001_RS10455	COG1116	anion transmembrane transporter activity
DSM105001_RS10475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DSM105001_RS10480	COG4974	Belongs to the 'phage' integrase family
DSM105001_RS10495	COG2359	stage V sporulation protein S
DSM105001_RS10500	COG0825	malonyl-CoA metabolic process
DSM105001_RS10505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DSM105001_RS10510	COG0439	Biotin carboxylase
DSM105001_RS10515	COG0511	ligase activity, forming carbon-carbon bonds
DSM105001_RS10535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DSM105001_RS10560	COG1136	(ABC) transporter
DSM105001_RS10570	COG2205	protein histidine kinase activity
DSM105001_RS10575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSM105001_RS10580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM105001_RS10600	COG1136	(ABC) transporter
DSM105001_RS10605	COG2205	protein histidine kinase activity
DSM105001_RS10610	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS10620	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS10625	COG5002	protein histidine kinase activity
DSM105001_RS10630	COG1136	(ABC) transporter
DSM105001_RS10630	COG0577	efflux transmembrane transporter activity
DSM105001_RS10665	COG1811	Na channel or pump
DSM105001_RS10670	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
DSM105001_RS10685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS10690	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DSM105001_RS10695	COG1923	regulation of RNA biosynthetic process
DSM105001_RS10700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSM105001_RS10705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSM105001_RS10710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSM105001_RS10715	COG1116	anion transmembrane transporter activity
DSM105001_RS10720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DSM105001_RS10725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM105001_RS10740	COG1733	regulation of RNA biosynthetic process
DSM105001_RS10750	COG0494	nUDIX hydrolase
DSM105001_RS10760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM105001_RS10765	COG2247	cell wall binding repeat
DSM105001_RS10765	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS10820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DSM105001_RS10840	COG0730	response to heat
DSM105001_RS10845	COG2207	Transcriptional regulator
DSM105001_RS10850	COG0596	Alpha beta hydrolase
DSM105001_RS10855	COG1309	transcriptional regulator
DSM105001_RS10870	COG1404	Belongs to the peptidase S8 family
DSM105001_RS10885	COG0129	dihydroxy-acid dehydratase activity
DSM105001_RS10915	COG2207	Transcriptional regulator
DSM105001_RS10920	COG2814	Major facilitator Superfamily
DSM105001_RS10940	COG1725	Transcriptional regulator
DSM105001_RS10965	COG1794	racemase activity, acting on amino acids and derivatives
DSM105001_RS10975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSM105001_RS10980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSM105001_RS10985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DSM105001_RS10990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DSM105001_RS11000	COG0456	acetyltransferase
DSM105001_RS11010	COG1309	transcriptional regulator
DSM105001_RS11025	COG3655	Transcriptional regulator
DSM105001_RS11040	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS11045	COG1737	Transcriptional regulator
DSM105001_RS11050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DSM105001_RS11055	COG1187	pseudouridine synthase activity
DSM105001_RS11060	COG0628	permease
DSM105001_RS11070	COG0019	diaminopimelate decarboxylase activity
DSM105001_RS11075	COG0527	aspartate kinase activity
DSM105001_RS11100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSM105001_RS11105	COG1597	lipid kinase activity
DSM105001_RS11135	COG0582	viral genome integration into host DNA
DSM105001_RS11145	COG0488	(ABC) transporter
DSM105001_RS11160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSM105001_RS11170	COG2080	2 iron, 2 sulfur cluster binding
DSM105001_RS11170	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM105001_RS11180	COG2233	PERMEase
DSM105001_RS11190	COG0167	dihydroorotate dehydrogenase activity
DSM105001_RS11195	COG0402	S-adenosylhomocysteine deaminase activity
DSM105001_RS11215	COG0402	S-adenosylhomocysteine deaminase activity
DSM105001_RS11240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM105001_RS11265	COG3829	transcription factor binding
DSM105001_RS11275	COG1401	restriction endodeoxyribonuclease activity
DSM105001_RS11290	COG4708	membrane
DSM105001_RS11300	COG2080	2 iron, 2 sulfur cluster binding
DSM105001_RS11300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM105001_RS11335	COG1131	(ABC) transporter
DSM105001_RS11345	COG2252	PERMEase
DSM105001_RS11350	COG0534	Mate efflux family protein
DSM105001_RS11360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DSM105001_RS11365	COG1349	DNA-binding transcription factor activity
DSM105001_RS11375	COG5002	protein histidine kinase activity
DSM105001_RS11380	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS11385	COG2217	Heavy metal translocating P-type atpase
DSM105001_RS11400	COG1217	gtp-binding protein TYPA
DSM105001_RS11405	COG0492	ferredoxin-NADP+ reductase activity
DSM105001_RS11450	COG1247	-acetyltransferase
DSM105001_RS11470	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DSM105001_RS11475	COG0750	zinc metalloprotease
DSM105001_RS11480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DSM105001_RS11500	COG4589	Belongs to the CDS family
DSM105001_RS11515	COG0233	cytoplasmic translational termination
DSM105001_RS11520	COG0528	UMP kinase activity
DSM105001_RS11525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DSM105001_RS11530	COG0052	Belongs to the universal ribosomal protein uS2 family
DSM105001_RS11535	COG1686	Belongs to the peptidase S11 family
DSM105001_RS11550	COG1971	Probably functions as a manganese efflux pump
DSM105001_RS11555	COG1193	negative regulation of DNA recombination
DSM105001_RS11570	COG2720	vancomycin resistance protein
DSM105001_RS11590	COG1363	Peptidase, m42
DSM105001_RS11600	COG1160	GTP binding
DSM105001_RS11605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DSM105001_RS11655	COG0039	L-malate dehydrogenase activity
DSM105001_RS11665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM105001_RS11665	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSM105001_RS11675	COG1151	hydroxylamine reductase activity
DSM105001_RS11695	COG1126	abc transporter atp-binding protein
DSM105001_RS11720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSM105001_RS11725	COG0437	4 iron, 4 sulfur cluster binding
DSM105001_RS11735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSM105001_RS11740	COG0596	Alpha beta hydrolase
DSM105001_RS11750	COG0513	Belongs to the DEAD box helicase family
DSM105001_RS11770	COG1705	Flagellar rod assembly protein muramidase FlgJ
DSM105001_RS11775	COG1554	hydrolase, family 65, central catalytic
DSM105001_RS11780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSM105001_RS11790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DSM105001_RS11800	COG2247	cell wall binding repeat
DSM105001_RS11800	COG2385	sporulation resulting in formation of a cellular spore
DSM105001_RS11810	COG1528	Iron-storage protein
DSM105001_RS11830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSM105001_RS11830	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSM105001_RS11840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM105001_RS11855	COG1309	transcriptional regulator
DSM105001_RS11865	COG0628	permease
DSM105001_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
DSM105001_RS11885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSM105001_RS11905	COG0288	reversible hydration of carbon dioxide
DSM105001_RS11925	COG0710	3-dehydroquinate dehydratase activity
DSM105001_RS11930	COG0582	viral genome integration into host DNA
DSM105001_RS11955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSM105001_RS11985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM105001_RS12040	COG1674	ftsk spoiiie
DSM105001_RS12045	COG2946	Replication initiation factor
DSM105001_RS12140	COG1733	regulation of RNA biosynthetic process
DSM105001_RS12145	COG1335	isochorismatase
DSM105001_RS12150	COG1733	regulation of RNA biosynthetic process
DSM105001_RS12165	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS12230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DSM105001_RS12235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM105001_RS12240	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DSM105001_RS12255	COG2203	Gaf domain
DSM105001_RS12255	COG5001	Diguanylate cyclase
DSM105001_RS12255	COG4251	negative regulation of phosphorylation
DSM105001_RS12255	COG3706	GGDEF domain
DSM105001_RS12260	COG0017	Asparaginyl-tRNA synthetase
DSM105001_RS12270	COG1404	Belongs to the peptidase S8 family
DSM105001_RS12275	COG1404	Belongs to the peptidase S8 family
DSM105001_RS12285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM105001_RS12300	COG1509	lysine 2,3-aminomutase activity
DSM105001_RS12305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS12310	COG1794	racemase activity, acting on amino acids and derivatives
DSM105001_RS12330	COG0662	Cupin 2, conserved barrel domain protein
DSM105001_RS12335	COG3104	oligopeptide transport
DSM105001_RS12340	COG0006	proline dipeptidase activity
DSM105001_RS12345	COG3104	oligopeptide transport
DSM105001_RS12350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM105001_RS12365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DSM105001_RS12365	COG0723	plastoquinol--plastocyanin reductase activity
DSM105001_RS12375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS12375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS12375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS12380	COG1105	Belongs to the carbohydrate kinase PfkB family
DSM105001_RS12385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS12385	COG3711	transcriptional antiterminator
DSM105001_RS12390	COG2365	Tyrosine phosphatase family
DSM105001_RS12410	COG1115	amino acid carrier protein
DSM105001_RS12415	COG0235	Class ii aldolase
DSM105001_RS12420	COG0235	Class ii aldolase
DSM105001_RS12425	COG1063	alcohol dehydrogenase
DSM105001_RS12430	COG3775	system Galactitol-specific IIC component
DSM105001_RS12435	COG3414	Phosphotransferase system galactitol-specific IIB component
DSM105001_RS12440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS12440	COG2213	PTS system mannitol-specific
DSM105001_RS12445	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS12445	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS12455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS12460	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DSM105001_RS12470	COG5002	protein histidine kinase activity
DSM105001_RS12580	COG3620	sequence-specific DNA binding
DSM105001_RS12605	COG3842	ATPase activity
DSM105001_RS12625	COG2205	protein histidine kinase activity
DSM105001_RS12630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM105001_RS12635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSM105001_RS12640	COG0698	ribose 5-phosphate isomerase
DSM105001_RS12645	COG3958	Transketolase
DSM105001_RS12650	COG3959	Transketolase, thiamine diphosphate binding domain
DSM105001_RS12665	COG3775	system Galactitol-specific IIC component
DSM105001_RS12670	COG3414	Phosphotransferase system galactitol-specific IIB component
DSM105001_RS12680	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DSM105001_RS12680	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DSM105001_RS12685	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DSM105001_RS12690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DSM105001_RS12695	COG0246	Mannitol dehydrogenase
DSM105001_RS12700	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS12705	COG3711	transcriptional antiterminator
DSM105001_RS12715	COG0516	GMP reductase activity
DSM105001_RS12715	COG0517	IMP dehydrogenase activity
DSM105001_RS12725	COG2801	Transposase and inactivated derivatives
DSM105001_RS12730	COG3853	Toxic anion resistance protein (TelA)
DSM105001_RS12740	COG1454	alcohol dehydrogenase
DSM105001_RS12745	COG0427	acetyl-CoA hydrolase
DSM105001_RS12760	COG1012	belongs to the aldehyde dehydrogenase family
DSM105001_RS12765	COG0427	acetyl-CoA hydrolase
DSM105001_RS12770	COG0490	domain, Protein
DSM105001_RS12770	COG2985	domain, Protein
DSM105001_RS12770	COG2985	domain, Protein
DSM105001_RS12770	COG0490	domain, Protein
DSM105001_RS12775	COG0583	DNA-binding transcription factor activity
DSM105001_RS12785	COG0006	proline dipeptidase activity
DSM105001_RS12815	COG3118	belongs to the thioredoxin family
DSM105001_RS12835	COG0561	phosphatase activity
DSM105001_RS12850	COG1116	anion transmembrane transporter activity
DSM105001_RS12855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM105001_RS12895	COG0157	Belongs to the NadC ModD family
DSM105001_RS12905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DSM105001_RS12910	COG1966	Carbon starvation protein
DSM105001_RS12925	COG0628	permease
DSM105001_RS12935	COG2364	Membrane
DSM105001_RS12940	COG3426	butyrate kinase activity
DSM105001_RS12965	COG2199	diguanylate cyclase activity
DSM105001_RS12970	COG2199	diguanylate cyclase activity
DSM105001_RS12970	COG2203	Gaf domain
DSM105001_RS13010	COG0072	phenylalanine-tRNA ligase activity
DSM105001_RS13010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM105001_RS13015	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DSM105001_RS13020	COG2176	DNA-directed DNA polymerase activity
DSM105001_RS13040	COG0037	tRNA processing
DSM105001_RS13055	COG3546	catalase activity
DSM105001_RS13060	COG1388	LysM domain
DSM105001_RS13060	COG3103	Sh3 type 3 domain protein
DSM105001_RS13060	COG0791	NLP P60 protein
DSM105001_RS13070	COG0551	DNA topoisomerase type I activity
DSM105001_RS13070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSM105001_RS13100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSM105001_RS13100	COG0574	Belongs to the PEP-utilizing enzyme family
DSM105001_RS13105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DSM105001_RS13110	COG0517	IMP dehydrogenase activity
DSM105001_RS13130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS13130	COG3711	transcriptional antiterminator
DSM105001_RS13135	COG3732	PTS system glucitol sorbitol-specific
DSM105001_RS13145	COG2207	Transcriptional regulator
DSM105001_RS13160	COG1115	amino acid carrier protein
DSM105001_RS13165	COG2223	nitrite transmembrane transporter activity
DSM105001_RS13170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS13175	COG0280	phosphate acetyltransferase
DSM105001_RS13195	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSM105001_RS13195	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSM105001_RS13205	COG1414	Transcriptional regulator
DSM105001_RS13215	COG0751	glycine-tRNA ligase activity
DSM105001_RS13220	COG0752	glycyl-tRNA synthetase alpha subunit
DSM105001_RS13230	COG1381	Involved in DNA repair and RecF pathway recombination
DSM105001_RS13240	COG2239	Acts as a magnesium transporter
DSM105001_RS13245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DSM105001_RS13250	COG0295	cytidine deaminase activity
DSM105001_RS13255	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DSM105001_RS13260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DSM105001_RS13265	COG1702	phosphate starvation-inducible protein PhoH
DSM105001_RS13285	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DSM105001_RS13290	COG1610	YqeY-like protein
DSM105001_RS13295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DSM105001_RS13300	COG0537	adenosine 5'-monophosphoramidase activity
DSM105001_RS13305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSM105001_RS13310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DSM105001_RS13315	COG2264	protein methyltransferase activity
DSM105001_RS13350	COG3842	ATPase activity
DSM105001_RS13355	COG2508	Transcriptional regulator
DSM105001_RS13360	COG0477	Major facilitator Superfamily
DSM105001_RS13370	COG0484	heat shock protein binding
DSM105001_RS13375	COG0443	Heat shock 70 kDa protein
DSM105001_RS13380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSM105001_RS13385	COG1420	regulation of RNA biosynthetic process
DSM105001_RS13390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSM105001_RS13395	COG0531	amino acid
DSM105001_RS13400	COG0617	tRNA 3'-terminal CCA addition
DSM105001_RS13405	COG0481	GTPase activity
DSM105001_RS13435	COG0268	Binds directly to 16S ribosomal RNA
DSM105001_RS13445	COG0658	competence protein
DSM105001_RS13445	COG2333	competence protein COMEC
DSM105001_RS13465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DSM105001_RS13475	COG3584	3D domain protein
DSM105001_RS13475	COG1388	LysM domain
DSM105001_RS13480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DSM105001_RS13495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSM105001_RS13500	COG0006	proline dipeptidase activity
DSM105001_RS13505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS13510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS13520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS13520	COG3711	transcriptional antiterminator
DSM105001_RS13525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS13530	COG1482	cell wall glycoprotein biosynthetic process
DSM105001_RS13535	COG5002	protein histidine kinase activity
DSM105001_RS13555	COG1596	polysaccharide export
DSM105001_RS13555	COG1555	photosystem II stabilization
DSM105001_RS13560	COG1686	Belongs to the peptidase S11 family
DSM105001_RS13570	COG0165	Argininosuccinate lyase
DSM105001_RS13575	COG0561	phosphatase activity
DSM105001_RS13580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM105001_RS13585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSM105001_RS13590	COG1876	peptidase activity
DSM105001_RS13595	COG1309	transcriptional regulator
DSM105001_RS13600	COG2814	Major facilitator Superfamily
DSM105001_RS13610	COG4977	sequence-specific DNA binding
DSM105001_RS13620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS13620	COG1263	PTS System
DSM105001_RS13625	COG3711	transcriptional antiterminator
DSM105001_RS13630	COG1263	PTS System
DSM105001_RS13630	COG2190	(PTS) system
DSM105001_RS13630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS13635	COG0251	oxidation-reduction process
DSM105001_RS13640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSM105001_RS13680	COG0582	viral genome integration into host DNA
DSM105001_RS13690	COG0495	leucyl-tRNA aminoacylation
DSM105001_RS13695	COG0799	negative regulation of ribosome biogenesis
DSM105001_RS13700	COG1713	HD superfamily hydrolase involved in NAD metabolism
DSM105001_RS13705	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DSM105001_RS13710	COG2137	regulation of response to DNA damage stimulus
DSM105001_RS13715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DSM105001_RS13735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM105001_RS13745	COG1136	(ABC) transporter
DSM105001_RS13745	COG0577	efflux transmembrane transporter activity
DSM105001_RS13755	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS13760	COG0737	Belongs to the 5'-nucleotidase family
DSM105001_RS13770	COG1234	tRNA 3'-trailer cleavage
DSM105001_RS13775	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSM105001_RS13780	COG1823	symporter activity
DSM105001_RS13805	COG4124	Belongs to the glycosyl hydrolase 26 family
DSM105001_RS13805	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DSM105001_RS13815	COG0395	ABC-type sugar transport system, permease component
DSM105001_RS13830	COG4821	SIS domain
DSM105001_RS13870	COG0742	ribosomal rna small subunit methyltransferase
DSM105001_RS13875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DSM105001_RS13880	COG1461	Dihydroxyacetone kinase
DSM105001_RS13885	COG1302	Protein conserved in bacteria
DSM105001_RS13890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DSM105001_RS13905	COG0789	Transcriptional regulator
DSM105001_RS13910	COG3711	transcriptional antiterminator
DSM105001_RS13910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS13915	COG3711	transcriptional antiterminator
DSM105001_RS13915	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS13920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS13925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS13930	COG0383	alpha-mannosidase activity
DSM105001_RS13955	COG1564	THIamine pyrophosphokinase
DSM105001_RS13960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSM105001_RS13965	COG1162	GTPase activity
DSM105001_RS13970	COG1028	Short-chain dehydrogenase reductase Sdr
DSM105001_RS13975	COG0515	serine threonine protein kinase
DSM105001_RS13975	COG2815	serine threonine protein kinase
DSM105001_RS13985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DSM105001_RS13990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSM105001_RS13990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSM105001_RS13995	COG2738	Putative neutral zinc metallopeptidase
DSM105001_RS14005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DSM105001_RS14010	COG0242	peptide deformylase activity
DSM105001_RS14015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DSM105001_RS14020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSM105001_RS14025	COG1758	RNA polymerase activity
DSM105001_RS14030	COG0194	GDP metabolic process
DSM105001_RS14035	COG1561	YicC-like family, N-terminal region
DSM105001_RS14040	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DSM105001_RS14050	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DSM105001_RS14055	COG0488	(ABC) transporter
DSM105001_RS14065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DSM105001_RS14070	COG0564	pseudouridine synthase activity
DSM105001_RS14075	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DSM105001_RS14085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DSM105001_RS14090	COG1966	Carbon starvation protein
DSM105001_RS14095	COG3279	Response regulator of the LytR AlgR family
DSM105001_RS14100	COG3275	phosphorelay sensor kinase activity
DSM105001_RS14125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DSM105001_RS14130	COG0531	amino acid
DSM105001_RS14135	COG0006	proline dipeptidase activity
DSM105001_RS14140	COG1307	EDD domain protein, DegV family
DSM105001_RS14155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSM105001_RS14160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSM105001_RS14170	COG2302	S4 RNA-binding domain
DSM105001_RS14180	COG1799	cell septum assembly
DSM105001_RS14185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DSM105001_RS14205	COG3830	Belongs to the UPF0237 family
DSM105001_RS14215	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DSM105001_RS14220	COG2271	Major facilitator Superfamily
DSM105001_RS14225	COG0531	amino acid
DSM105001_RS14230	COG0006	proline dipeptidase activity
DSM105001_RS14240	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSM105001_RS14245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DSM105001_RS14250	COG1160	GTP binding
DSM105001_RS14275	COG5002	protein histidine kinase activity
DSM105001_RS14280	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS14290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DSM105001_RS14295	COG1873	PFAM PRC-barrel domain
DSM105001_RS14300	COG1191	sigma factor activity
DSM105001_RS14305	COG1191	sigma factor activity
DSM105001_RS14320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DSM105001_RS14325	COG3856	small basic protein
DSM105001_RS14345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM105001_RS14350	COG0772	Belongs to the SEDS family
DSM105001_RS14355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DSM105001_RS14360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DSM105001_RS14365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DSM105001_RS14370	COG0768	penicillin binding
DSM105001_RS14380	COG0275	rRNA processing
DSM105001_RS14385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DSM105001_RS14390	COG0612	Peptidase, M16
DSM105001_RS14400	COG0012	GTP binding
DSM105001_RS14410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DSM105001_RS14420	COG2190	(PTS) system
DSM105001_RS14420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS14420	COG1263	PTS System
DSM105001_RS14425	COG3711	transcriptional antiterminator
DSM105001_RS14430	COG0025	NhaP-type Na H and K H
DSM105001_RS14435	COG4608	Belongs to the ABC transporter superfamily
DSM105001_RS14440	COG0444	Belongs to the ABC transporter superfamily
DSM105001_RS14450	COG0601	transmembrane transport
DSM105001_RS14455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DSM105001_RS14460	COG0583	DNA-binding transcription factor activity
DSM105001_RS14465	COG0183	Belongs to the thiolase family
DSM105001_RS14470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DSM105001_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
DSM105001_RS14485	COG2610	gluconate transmembrane transporter activity
DSM105001_RS14490	COG2340	Cysteine-rich secretory protein family
DSM105001_RS14500	COG4869	propanediol catabolic process
DSM105001_RS14535	COG2081	HI0933 family
DSM105001_RS14540	COG0671	phosphoesterase, PA-phosphatase related
DSM105001_RS14550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM105001_RS14565	COG2502	aspartate--ammonia ligase
DSM105001_RS14570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSM105001_RS14575	COG1473	amidohydrolase
DSM105001_RS14585	COG3366	ferrous iron transmembrane transporter activity
DSM105001_RS14610	COG2252	PERMEase
DSM105001_RS14615	COG0402	S-adenosylhomocysteine deaminase activity
DSM105001_RS14625	COG2271	Major facilitator Superfamily
DSM105001_RS14645	COG0583	DNA-binding transcription factor activity
DSM105001_RS14655	COG1376	ErfK ybiS ycfS ynhG family protein
DSM105001_RS14660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DSM105001_RS14665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSM105001_RS14690	COG4509	Sortase family
DSM105001_RS14710	COG0726	polysaccharide deacetylase
DSM105001_RS14715	COG3069	C4-dicarboxylate transmembrane transporter activity
DSM105001_RS14720	COG0642	Histidine kinase
DSM105001_RS14720	COG5002	protein histidine kinase activity
DSM105001_RS14725	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS14740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DSM105001_RS14745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM105001_RS14765	COG1937	Protein conserved in bacteria
DSM105001_RS14780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSM105001_RS14785	COG1757	Na H antiporter
DSM105001_RS14795	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS14795	COG2247	cell wall binding repeat
DSM105001_RS14800	COG0583	DNA-binding transcription factor activity
DSM105001_RS14805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSM105001_RS14815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DSM105001_RS14820	COG0124	histidyl-tRNA synthetase
DSM105001_RS14825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DSM105001_RS14830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSM105001_RS14835	COG1490	D-aminoacyl-tRNA deacylase activity
DSM105001_RS14840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DSM105001_RS14845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DSM105001_RS14850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DSM105001_RS14850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DSM105001_RS14890	COG5001	Diguanylate cyclase
DSM105001_RS14895	COG3706	GGDEF domain
DSM105001_RS14905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS14930	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS14935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSM105001_RS14945	COG0561	phosphatase activity
DSM105001_RS14950	COG1316	TRANSCRIPTIONal
DSM105001_RS14955	COG1316	TRANSCRIPTIONal
DSM105001_RS14960	COG1649	PFAM Uncharacterised BCR, COG1649
DSM105001_RS14975	COG0438	transferase activity, transferring glycosyl groups
DSM105001_RS14980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DSM105001_RS14985	COG1215	transferase activity, transferring glycosyl groups
DSM105001_RS14995	COG1215	transferase activity, transferring glycosyl groups
DSM105001_RS15000	COG1215	transferase activity, transferring glycosyl groups
DSM105001_RS15000	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DSM105001_RS15005	COG1216	Glycosyl transferase, family 2
DSM105001_RS15025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSM105001_RS15030	COG0728	peptidoglycan biosynthetic process
DSM105001_RS15035	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS15035	COG2247	cell wall binding repeat
DSM105001_RS15040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DSM105001_RS15045	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS15055	COG2247	cell wall binding repeat
DSM105001_RS15055	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS15065	COG2246	polysaccharide biosynthetic process
DSM105001_RS15070	COG2247	cell wall binding repeat
DSM105001_RS15070	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS15085	COG0653	protein targeting
DSM105001_RS15120	COG2247	cell wall binding repeat
DSM105001_RS15120	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS15140	COG0343	queuine tRNA-ribosyltransferase activity
DSM105001_RS15150	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DSM105001_RS15155	COG2255	four-way junction helicase activity
DSM105001_RS15160	COG0632	four-way junction helicase activity
DSM105001_RS15165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DSM105001_RS15190	COG2610	gluconate transmembrane transporter activity
DSM105001_RS15195	COG2084	Dehydrogenase
DSM105001_RS15215	COG1132	(ABC) transporter
DSM105001_RS15235	COG0700	Nucleoside recognition
DSM105001_RS15240	COG3366	ferrous iron transmembrane transporter activity
DSM105001_RS15245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS15260	COG1902	pentaerythritol trinitrate reductase activity
DSM105001_RS15270	COG0436	Aminotransferase
DSM105001_RS15275	COG0697	spore germination
DSM105001_RS15290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSM105001_RS15305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSM105001_RS15310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DSM105001_RS15315	COG1473	amidohydrolase
DSM105001_RS15320	COG3949	Membrane
DSM105001_RS15335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSM105001_RS15350	COG0604	alcohol dehydrogenase
DSM105001_RS15360	COG1592	Rubrerythrin
DSM105001_RS15365	COG0789	Transcriptional regulator
DSM105001_RS15375	COG1664	Polymer-forming cytoskeletal
DSM105001_RS15380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSM105001_RS15380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSM105001_RS15385	COG1349	DNA-binding transcription factor activity
DSM105001_RS15390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DSM105001_RS15395	COG1696	Membrane protein involved in D-alanine export
DSM105001_RS15400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DSM105001_RS15410	COG0673	inositol 2-dehydrogenase activity
DSM105001_RS15420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSM105001_RS15425	COG1253	flavin adenine dinucleotide binding
DSM105001_RS15430	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DSM105001_RS15450	COG3290	protein histidine kinase activity
DSM105001_RS15450	COG3829	transcription factor binding
DSM105001_RS15455	COG2267	carboxylic ester hydrolase activity
DSM105001_RS15465	COG0312	modulator of DNA gyrase
DSM105001_RS15470	COG0312	modulator of DNA gyrase
DSM105001_RS15495	COG2721	sulfolactate sulfo-lyase activity
DSM105001_RS15510	COG1120	ATPase activity
DSM105001_RS15515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSM105001_RS15520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSM105001_RS15535	COG1447	Phosphotransferase system cellobiose-specific component IIA
DSM105001_RS15540	COG3394	polysaccharide catabolic process
DSM105001_RS15545	COG1486	melibiose metabolic process
DSM105001_RS15550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS15560	COG2188	Transcriptional regulator
DSM105001_RS15565	COG0534	Mate efflux family protein
DSM105001_RS15570	COG2199	diguanylate cyclase activity
DSM105001_RS15575	COG1178	ABC-type Fe3 transport system permease component
DSM105001_RS15580	COG3842	ATPase activity
DSM105001_RS15585	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM105001_RS15590	COG1394	ATPase activity, coupled to movement of substances
DSM105001_RS15595	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DSM105001_RS15600	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DSM105001_RS15615	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DSM105001_RS15620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM105001_RS15625	COG1269	ATP hydrolysis coupled proton transport
DSM105001_RS15650	COG5001	Diguanylate cyclase
DSM105001_RS15650	COG3300	MHYT domain
DSM105001_RS15655	COG1454	alcohol dehydrogenase
DSM105001_RS15655	COG1012	belongs to the aldehyde dehydrogenase family
DSM105001_RS15665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSM105001_RS15675	COG0318	PFAM AMP-dependent synthetase and ligase
DSM105001_RS15680	COG0183	Belongs to the thiolase family
DSM105001_RS15685	COG1268	BioY protein
DSM105001_RS15700	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DSM105001_RS15715	COG1203	CRISPR-associated helicase, Cas3
DSM105001_RS15745	COG0577	efflux transmembrane transporter activity
DSM105001_RS15750	COG1136	(ABC) transporter
DSM105001_RS15755	COG1968	undecaprenyl-diphosphatase activity
DSM105001_RS15760	COG2205	protein histidine kinase activity
DSM105001_RS15765	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS15780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSM105001_RS15795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSM105001_RS15800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSM105001_RS15810	COG1120	ATPase activity
DSM105001_RS15815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DSM105001_RS15825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM105001_RS15830	COG0179	Fumarylacetoacetate (FAA) hydrolase
DSM105001_RS15855	COG1454	alcohol dehydrogenase
DSM105001_RS15860	COG1376	ErfK ybiS ycfS ynhG family protein
DSM105001_RS15870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSM105001_RS15875	COG0785	Cytochrome C biogenesis protein
DSM105001_RS15880	COG1733	regulation of RNA biosynthetic process
DSM105001_RS15885	COG0383	alpha-mannosidase activity
DSM105001_RS15890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS15895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS15900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS15900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS15900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS15905	COG3711	transcriptional antiterminator
DSM105001_RS15905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS15910	COG4975	Glucose uptake
DSM105001_RS15945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSM105001_RS15960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSM105001_RS15960	COG0517	IMP dehydrogenase activity
DSM105001_RS15965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSM105001_RS15970	COG1263	PTS System
DSM105001_RS15970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS15975	COG3711	transcriptional antiterminator
DSM105001_RS15980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DSM105001_RS15985	COG3118	belongs to the thioredoxin family
DSM105001_RS15995	COG0384	phenazine biosynthesis protein PhzF
DSM105001_RS16015	COG0542	response to heat
DSM105001_RS16025	COG2267	carboxylic ester hydrolase activity
DSM105001_RS16040	COG1737	Transcriptional regulator
DSM105001_RS16045	COG2971	BadF BadG BcrA BcrD
DSM105001_RS16050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DSM105001_RS16060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS16075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DSM105001_RS16080	COG0642	Histidine kinase
DSM105001_RS16095	COG1136	(ABC) transporter
DSM105001_RS16105	COG2190	(PTS) system
DSM105001_RS16120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16120	COG1263	PTS System
DSM105001_RS16135	COG2115	Belongs to the xylose isomerase family
DSM105001_RS16140	COG1070	Carbohydrate kinase
DSM105001_RS16155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16155	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS16160	COG3716	PTS system mannose fructose sorbose family IID component
DSM105001_RS16190	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DSM105001_RS16215	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DSM105001_RS16220	COG0191	fructose-bisphosphate aldolase activity
DSM105001_RS16225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS16240	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS16250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS16265	COG1929	Belongs to the glycerate kinase type-1 family
DSM105001_RS16270	COG0383	alpha-mannosidase activity
DSM105001_RS16275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS16275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16285	COG3394	polysaccharide catabolic process
DSM105001_RS16290	COG1263	PTS System
DSM105001_RS16290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16290	COG2190	(PTS) system
DSM105001_RS16295	COG2188	Transcriptional regulator
DSM105001_RS16300	COG0366	Alpha amylase catalytic
DSM105001_RS16310	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DSM105001_RS16320	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS16325	COG2190	(PTS) system
DSM105001_RS16325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16325	COG1263	PTS System
DSM105001_RS16330	COG3711	transcriptional antiterminator
DSM105001_RS16340	COG1288	antiporter activity
DSM105001_RS16345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16345	COG1263	PTS System
DSM105001_RS16350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSM105001_RS16360	COG0561	phosphatase activity
DSM105001_RS16365	COG1454	alcohol dehydrogenase
DSM105001_RS16370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DSM105001_RS16375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS16375	COG3711	transcriptional antiterminator
DSM105001_RS16380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DSM105001_RS16385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSM105001_RS16390	COG0205	6-phosphofructokinase activity
DSM105001_RS16400	COG1473	amidohydrolase
DSM105001_RS16405	COG1473	amidohydrolase
DSM105001_RS16415	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS16420	COG1263	PTS System
DSM105001_RS16420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16420	COG2190	(PTS) system
DSM105001_RS16435	COG1819	glycosyl
DSM105001_RS16440	COG3620	sequence-specific DNA binding
DSM105001_RS16450	COG0640	Transcriptional regulator
DSM105001_RS16460	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS16465	COG1263	PTS System
DSM105001_RS16465	COG2190	(PTS) system
DSM105001_RS16465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16470	COG3711	transcriptional antiterminator
DSM105001_RS16475	COG1263	PTS System
DSM105001_RS16475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSM105001_RS16490	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS16500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS16500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16505	COG3711	transcriptional antiterminator
DSM105001_RS16510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS16510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DSM105001_RS16515	COG0191	fructose-bisphosphate aldolase activity
DSM105001_RS16520	COG2723	6-phospho-beta-galactosidase activity
DSM105001_RS16525	COG2190	(PTS) system
DSM105001_RS16525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS16525	COG1263	PTS System
DSM105001_RS16530	COG3711	transcriptional antiterminator
DSM105001_RS16550	COG0693	protein deglycase activity
DSM105001_RS16565	COG4509	Sortase family
DSM105001_RS16605	COG3620	sequence-specific DNA binding
DSM105001_RS16625	COG0582	viral genome integration into host DNA
DSM105001_RS16650	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DSM105001_RS16675	COG1131	(ABC) transporter
DSM105001_RS16685	COG0557	exoribonuclease II activity
DSM105001_RS16700	COG1881	PFAM PEBP family protein
DSM105001_RS16725	COG0148	phosphopyruvate hydratase activity
DSM105001_RS16730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DSM105001_RS16735	COG0149	triose-phosphate isomerase activity
DSM105001_RS16740	COG0126	phosphoglycerate kinase activity
DSM105001_RS16750	COG2390	Transcriptional regulator
DSM105001_RS16755	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DSM105001_RS16760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DSM105001_RS16770	COG0167	dihydroorotate dehydrogenase activity
DSM105001_RS16780	COG0402	S-adenosylhomocysteine deaminase activity
DSM105001_RS16785	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DSM105001_RS16805	COG3829	transcription factor binding
DSM105001_RS16810	COG0251	oxidation-reduction process
DSM105001_RS16820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DSM105001_RS16825	COG0789	Transcriptional regulator
DSM105001_RS16835	COG2247	cell wall binding repeat
DSM105001_RS16835	COG0860	N-Acetylmuramoyl-L-alanine amidase
DSM105001_RS16845	COG2207	Transcriptional regulator
DSM105001_RS16850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSM105001_RS16860	COG0789	Transcriptional regulator
DSM105001_RS16885	COG2205	protein histidine kinase activity
DSM105001_RS16885	COG2770	Histidine kinase
DSM105001_RS16890	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS16895	COG0706	membrane insertase activity
DSM105001_RS16905	COG0778	Nitroreductase
DSM105001_RS16915	COG0534	Mate efflux family protein
DSM105001_RS16940	COG2226	methyltransferase
DSM105001_RS16960	COG1732	Glycine betaine
DSM105001_RS16965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DSM105001_RS16975	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DSM105001_RS16980	COG2226	methyltransferase
DSM105001_RS16990	COG1473	amidohydrolase
DSM105001_RS16995	COG1760	l-serine dehydratase
DSM105001_RS17005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DSM105001_RS17010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM105001_RS17015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DSM105001_RS17020	COG2171	N-acyltransferase activity
DSM105001_RS17030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DSM105001_RS17040	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DSM105001_RS17045	COG3681	Belongs to the UPF0597 family
DSM105001_RS17050	COG3829	transcription factor binding
DSM105001_RS17060	COG2226	methyltransferase
DSM105001_RS17085	COG5275	peptidyl-tyrosine sulfation
DSM105001_RS17085	COG0252	asparaginase activity
DSM105001_RS17090	COG5275	peptidyl-tyrosine sulfation
DSM105001_RS17090	COG0252	asparaginase activity
DSM105001_RS17105	COG5275	peptidyl-tyrosine sulfation
DSM105001_RS17105	COG0252	asparaginase activity
DSM105001_RS17120	COG4656	Part of a membrane complex involved in electron transport
DSM105001_RS17125	COG0726	polysaccharide deacetylase
DSM105001_RS17150	COG0285	dihydrofolate synthase activity
DSM105001_RS17160	COG3279	Response regulator of the LytR AlgR family
DSM105001_RS17165	COG0525	valine-tRNA ligase activity
DSM105001_RS17170	COG0726	polysaccharide deacetylase
DSM105001_RS17185	COG0704	Plays a role in the regulation of phosphate uptake
DSM105001_RS17190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DSM105001_RS17195	COG0581	inorganic phosphate transmembrane transporter activity
DSM105001_RS17200	COG0573	inorganic phosphate transmembrane transporter activity
DSM105001_RS17220	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS17225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DSM105001_RS17230	COG1164	Oligoendopeptidase f
DSM105001_RS17235	COG1285	pathogenesis
DSM105001_RS17260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DSM105001_RS17265	COG3716	PTS system mannose fructose sorbose family IID component
DSM105001_RS17270	COG3715	PTS system
DSM105001_RS17275	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS17275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS17280	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DSM105001_RS17280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DSM105001_RS17290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DSM105001_RS17305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DSM105001_RS17310	COG0166	Belongs to the GPI family
DSM105001_RS17320	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DSM105001_RS17335	COG3012	SEC-C Motif Domain Protein
DSM105001_RS17335	COG1405	negative regulation of cell septum assembly
DSM105001_RS17360	COG1459	type II secretion system
DSM105001_RS17365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM105001_RS17380	COG2814	Major facilitator Superfamily
DSM105001_RS17385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSM105001_RS17390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSM105001_RS17400	COG2059	Chromate
DSM105001_RS17405	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DSM105001_RS17410	COG0740	serine-type endopeptidase activity
DSM105001_RS17415	COG0544	peptidyl-prolyl cis-trans isomerase activity
DSM105001_RS17430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSM105001_RS17450	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSM105001_RS17450	COG0493	'glutamate synthase
DSM105001_RS17460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSM105001_RS17470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DSM105001_RS17520	COG0463	Glycosyl transferase, family 2
DSM105001_RS17520	COG0457	Tetratricopeptide repeat
DSM105001_RS17535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS17545	COG0778	Nitroreductase
DSM105001_RS17550	COG1733	regulation of RNA biosynthetic process
DSM105001_RS17555	COG0693	protein deglycase activity
DSM105001_RS17560	COG1522	sequence-specific DNA binding
DSM105001_RS17565	COG0488	(ABC) transporter
DSM105001_RS17570	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS17590	COG4555	ABC transporter
DSM105001_RS17595	COG5001	Diguanylate cyclase
DSM105001_RS17630	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DSM105001_RS17660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSM105001_RS17675	COG0745	RESPONSE REGULATOR receiver
DSM105001_RS17680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSM105001_RS17760	COG2946	Replication initiation factor
DSM105001_RS17765	COG1674	ftsk spoiiie
DSM105001_RS17800	COG0205	6-phosphofructokinase activity
DSM105001_RS17810	COG1481	regulation of sporulation
DSM105001_RS17825	COG1660	Displays ATPase and GTPase activities
DSM105001_RS17835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DSM105001_RS17840	COG2116	formate transmembrane transporter activity
DSM105001_RS17845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DSM105001_RS17875	COG0322	excinuclease ABC activity
DSM105001_RS17885	COG0556	nucleotide-excision repair
DSM105001_RS17895	COG1653	transport
DSM105001_RS17905	COG1175	transmembrane transport
DSM105001_RS17910	COG3842	ATPase activity
DSM105001_RS17930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DSM105001_RS17930	COG1648	precorrin-2 dehydrogenase activity
DSM105001_RS17935	COG0113	porphobilinogen synthase activity
DSM105001_RS17945	COG0181	hydroxymethylbilane synthase activity
DSM105001_RS17955	COG2099	Precorrin-6x reductase
DSM105001_RS17985	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DSM105001_RS18000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DSM105001_RS18010	COG1797	cobyrinic acid a,c-diamide synthase activity
DSM105001_RS18015	COG1492	cobalamin metabolic process
DSM105001_RS18020	COG0406	alpha-ribazole phosphatase activity
DSM105001_RS18025	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DSM105001_RS18030	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
DSM105001_RS18035	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DSM105001_RS18050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSM105001_RS18065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS18070	COG1447	Phosphotransferase system cellobiose-specific component IIA
DSM105001_RS18075	COG1363	Peptidase, m42
DSM105001_RS18080	COG3711	transcriptional antiterminator
DSM105001_RS18085	COG0191	fructose-bisphosphate aldolase activity
DSM105001_RS18090	COG2222	sugar isomerase
DSM105001_RS18105	COG2188	Transcriptional regulator
DSM105001_RS18120	COG0793	Belongs to the peptidase S41A family
DSM105001_RS18120	COG3409	Peptidoglycan-binding domain 1 protein
DSM105001_RS18125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DSM105001_RS18135	COG3949	Membrane
DSM105001_RS18140	COG3958	Transketolase
DSM105001_RS18145	COG3959	Transketolase, thiamine diphosphate binding domain
DSM105001_RS18150	COG2337	Toxic component of a toxin-antitoxin (TA) module
DSM105001_RS18170	COG0517	IMP dehydrogenase activity
DSM105001_RS18170	COG0516	GMP reductase activity
DSM105001_RS18175	COG0736	holo-[acyl-carrier-protein] synthase activity
DSM105001_RS18180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DSM105001_RS18185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DSM105001_RS18190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DSM105001_RS18195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DSM105001_RS18200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM105001_RS18205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DSM105001_RS18210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DSM105001_RS18235	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DSM105001_RS18235	COG3608	succinylglutamate desuccinylase aspartoacylase
DSM105001_RS18240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DSM105001_RS18245	COG0698	ribose 5-phosphate isomerase
DSM105001_RS18255	COG0009	L-threonylcarbamoyladenylate synthase
DSM105001_RS18265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DSM105001_RS18270	COG2890	protein-(glutamine-N5) methyltransferase activity
DSM105001_RS18275	COG3872	metal-dependent enzyme
DSM105001_RS18280	COG0254	rRNA binding
DSM105001_RS18285	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DSM105001_RS18290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DSM105001_RS18300	COG2208	phosphoserine phosphatase activity
DSM105001_RS18305	COG0248	Ppx GppA phosphatase
DSM105001_RS18325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DSM105001_RS18335	COG3956	TIGRFAM MazG family protein
DSM105001_RS18340	COG2244	polysaccharide biosynthetic process
DSM105001_RS18345	COG2002	toxin-antitoxin pair type II binding
DSM105001_RS18350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSM105001_RS18355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DSM105001_RS18360	COG0193	aminoacyl-tRNA hydrolase activity
DSM105001_RS18410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DSM105001_RS18425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DSM105001_RS18430	COG2088	sporulation resulting in formation of a cellular spore
DSM105001_RS18435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DSM105001_RS18440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DSM105001_RS18450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DSM105001_RS18455	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSM105001_RS18465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSM105001_RS18470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DSM105001_RS18475	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM105001_RS18485	COG1840	ABC-type Fe3 transport system, periplasmic component
DSM105001_RS18495	COG3842	ATPase activity
DSM105001_RS18500	COG0613	PHP domain protein
DSM105001_RS18505	COG3454	Phosphonate metabolism
DSM105001_RS18510	COG4778	phosphonate C-P lyase system protein PhnL
DSM105001_RS18515	COG4107	phosphonate C-P lyase system protein PhnK
DSM105001_RS18520	COG3627	carbon phosphorus lyase activity
DSM105001_RS18540	COG0084	hydrolase, TatD family'
DSM105001_RS18545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM105001_RS18545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSM105001_RS18550	COG0700	Nucleoside recognition
DSM105001_RS18560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DSM105001_RS18565	COG1522	sequence-specific DNA binding
DSM105001_RS18570	COG0617	tRNA 3'-terminal CCA addition
DSM105001_RS18575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DSM105001_RS18580	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DSM105001_RS18585	COG1774	PSP1 C-terminal conserved region
DSM105001_RS18590	COG0470	DNA polymerase III
DSM105001_RS18595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSM105001_RS18600	COG1982	Orn Lys Arg decarboxylase major
DSM105001_RS18605	COG2155	Conserved Protein
DSM105001_RS18630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DSM105001_RS18635	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DSM105001_RS18645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DSM105001_RS18655	COG3191	aminopeptidase activity
DSM105001_RS18665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSM105001_RS18670	COG0037	tRNA processing
DSM105001_RS18680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DSM105001_RS18695	COG1802	Transcriptional regulator
DSM105001_RS18700	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DSM105001_RS18730	COG0653	protein targeting
DSM105001_RS18755	COG2271	Major facilitator Superfamily
DSM105001_RS18760	COG0626	cystathionine gamma-synthase activity
DSM105001_RS18785	COG0564	pseudouridine synthase activity
DSM105001_RS18790	COG4978	Transcriptional regulator
DSM105001_RS18790	COG0789	Transcriptional regulator
DSM105001_RS18800	COG1136	(ABC) transporter
DSM105001_RS18800	COG0577	efflux transmembrane transporter activity
DSM105001_RS18805	COG5002	protein histidine kinase activity
DSM105001_RS18825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DSM105001_RS18835	COG0284	orotidine-5'-phosphate decarboxylase activity
DSM105001_RS18855	COG0646	methionine synthase
DSM105001_RS18855	COG1410	methionine synthase
DSM105001_RS18865	COG1854	S-ribosylhomocysteine lyase activity
DSM105001_RS18880	COG1876	peptidase activity
DSM105001_RS18885	COG0037	tRNA processing
DSM105001_RS18890	COG1408	metallophosphoesterase
DSM105001_RS18905	COG1141	Ferredoxin
DSM105001_RS18910	COG3964	amidohydrolase
DSM105001_RS18920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DSM105001_RS18930	COG0346	lactoylglutathione lyase activity
DSM105001_RS18935	COG0534	Mate efflux family protein
DSM105001_RS18950	COG0789	Transcriptional regulator
DSM105001_RS18950	COG4978	Transcriptional regulator
DSM105001_RS18960	COG5504	Zn-dependent protease
DSM105001_RS18970	COG0519	Catalyzes the synthesis of GMP from XMP
DSM105001_RS18980	COG1357	PFAM Pentapeptide repeats (8 copies)
DSM105001_RS18985	COG2824	Alkylphosphonate utilization operon protein PhnA
DSM105001_RS18990	COG1136	(ABC) transporter
DSM105001_RS18990	COG0577	efflux transmembrane transporter activity
DSM105001_RS19000	COG3447	MASE1 domain protein
DSM105001_RS19000	COG5001	Diguanylate cyclase
DSM105001_RS19000	COG5002	protein histidine kinase activity
DSM105001_RS19005	COG0352	thiamine-phosphate diphosphorylase activity
DSM105001_RS19010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DSM105001_RS19015	COG0517	IMP dehydrogenase activity
DSM105001_RS19015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSM105001_RS19035	COG1335	isochorismatase
DSM105001_RS19045	COG0789	Transcriptional regulator
DSM105001_RS19075	COG0583	DNA-binding transcription factor activity
DSM105001_RS19080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSM105001_RS19080	COG1522	sequence-specific DNA binding
DSM105001_RS19095	COG3964	amidohydrolase
DSM105001_RS19105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS19110	COG2188	Transcriptional regulator
DSM105001_RS19115	COG1447	Phosphotransferase system cellobiose-specific component IIA
DSM105001_RS19120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS19125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DSM105001_RS19130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DSM105001_RS19135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DSM105001_RS19150	COG1484	DNA-dependent DNA replication
DSM105001_RS19175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSM105001_RS19185	COG0305	Participates in initiation and elongation during chromosome replication
DSM105001_RS19190	COG0359	binds to the 23S rRNA
DSM105001_RS19195	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DSM105001_RS19210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DSM105001_RS19215	COG0629	single-stranded DNA binding
DSM105001_RS19220	COG0360	Binds together with S18 to 16S ribosomal RNA
DSM105001_RS19225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DSM105001_RS19240	COG0425	Belongs to the sulfur carrier protein TusA family
DSM105001_RS19255	COG1104	cysteine desulfurase activity
DSM105001_RS19260	COG1475	DNA binding
DSM105001_RS19265	COG1192	Involved in chromosome partitioning
DSM105001_RS19270	COG1475	DNA binding
DSM105001_RS19275	COG0357	Ribosomal RNA small subunit methyltransferase G
DSM105001_RS19280	COG0445	tRNA wobble uridine modification
DSM105001_RS19285	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DSM105001_RS19290	COG1847	R3H domain protein
DSM105001_RS19295	COG0706	membrane insertase activity
DSM105001_RS19300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DSM105001_RS19305	COG0594	ribonuclease P activity
DSM105001_RS19310	COG0230	Belongs to the bacterial ribosomal protein bL34 family