locus-tag	class	description
CDIF29627_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDIF29627_RS00010	COG0592	DNA-directed DNA polymerase activity
CDIF29627_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDIF29627_RS00025	COG0187	DNA topoisomerase II activity
CDIF29627_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDIF29627_RS00045	COG1366	Belongs to the anti-sigma-factor antagonist family
CDIF29627_RS00055	COG1191	sigma factor activity
CDIF29627_RS00105	COG1827	regulation of RNA biosynthetic process
CDIF29627_RS00110	COG0668	transmembrane transport
CDIF29627_RS00115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDIF29627_RS00120	COG0590	tRNA wobble adenosine to inosine editing
CDIF29627_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDIF29627_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDIF29627_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDIF29627_RS00155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29627_RS00395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDIF29627_RS00400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDIF29627_RS00405	COG4463	regulation of RNA biosynthetic process
CDIF29627_RS00410	COG3880	PFAM UvrB UvrC protein
CDIF29627_RS00415	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CDIF29627_RS00420	COG0542	response to heat
CDIF29627_RS00425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDIF29627_RS00430	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CDIF29627_RS00435	COG4956	integral membrane protein (PIN domain superfamily)
CDIF29627_RS00455	COG3507	Belongs to the glycosyl hydrolase 43 family
CDIF29627_RS00465	COG2390	Transcriptional regulator
CDIF29627_RS00470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDIF29627_RS00475	COG0022	dehydrogenase e1 component
CDIF29627_RS00480	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDIF29627_RS00485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDIF29627_RS00490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS00490	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS00500	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29627_RS00505	COG3775	system Galactitol-specific IIC component
CDIF29627_RS00520	COG0095	Lipoate-protein ligase
CDIF29627_RS00525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDIF29627_RS00530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDIF29627_RS00535	COG0442	prolyl-tRNA aminoacylation
CDIF29627_RS00540	COG0442	prolyl-tRNA aminoacylation
CDIF29627_RS00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDIF29627_RS00555	COG0215	cysteine-tRNA ligase activity
CDIF29627_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDIF29627_RS00575	COG3688	RNA-binding protein containing a PIN domain
CDIF29627_RS00585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDIF29627_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDIF29627_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
CDIF29627_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDIF29627_RS00610	COG0081	regulation of translation
CDIF29627_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDIF29627_RS00620	COG0222	ribosome binding
CDIF29627_RS00630	COG0085	RNA polymerase activity
CDIF29627_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDIF29627_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDIF29627_RS00645	COG0049	tRNA binding
CDIF29627_RS00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDIF29627_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDIF29627_RS00660	COG0051	transcription antitermination factor activity, RNA binding
CDIF29627_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDIF29627_RS00670	COG0088	Forms part of the polypeptide exit tunnel
CDIF29627_RS00675	COG0089	rRNA binding
CDIF29627_RS00680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDIF29627_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDIF29627_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDIF29627_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDIF29627_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDIF29627_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
CDIF29627_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDIF29627_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDIF29627_RS00720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDIF29627_RS00725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDIF29627_RS00730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDIF29627_RS00735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDIF29627_RS00740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDIF29627_RS00745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDIF29627_RS00750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDIF29627_RS00755	COG1841	ribosomal large subunit assembly
CDIF29627_RS00760	COG0200	Binds to the 23S rRNA
CDIF29627_RS00770	COG0563	adenylate kinase activity
CDIF29627_RS00775	COG0024	Methionine aminopeptidase
CDIF29627_RS00785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDIF29627_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDIF29627_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDIF29627_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDIF29627_RS00805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDIF29627_RS00810	COG0202	RNA polymerase activity
CDIF29627_RS00815	COG0203	ribosomal protein L17
CDIF29627_RS00820	COG1122	ATPase activity
CDIF29627_RS00825	COG1122	ATPase activity
CDIF29627_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDIF29627_RS00835	COG0101	tRNA pseudouridine synthase activity
CDIF29627_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDIF29627_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDIF29627_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS01095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDIF29627_RS01110	COG0280	phosphate acetyltransferase
CDIF29627_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29627_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDIF29627_RS01155	COG2897	thiosulfate sulfurtransferase activity
CDIF29627_RS01165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDIF29627_RS01170	COG2385	sporulation resulting in formation of a cellular spore
CDIF29627_RS01180	COG1609	Transcriptional regulator
CDIF29627_RS01185	COG1077	Cell shape determining protein MreB Mrl
CDIF29627_RS01190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDIF29627_RS01200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDIF29627_RS01205	COG3949	Membrane
CDIF29627_RS01210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDIF29627_RS01215	COG1040	competence protein
CDIF29627_RS01220	COG3711	transcriptional antiterminator
CDIF29627_RS01220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS01225	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29627_RS01230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS01235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS01245	COG1446	asparaginase
CDIF29627_RS01250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS01255	COG3142	Participates in the control of copper homeostasis
CDIF29627_RS01260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDIF29627_RS01265	COG0653	protein targeting
CDIF29627_RS01270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDIF29627_RS01275	COG2183	response to ionizing radiation
CDIF29627_RS01280	COG1228	amidohydrolase
CDIF29627_RS01295	COG0802	atpase or kinase
CDIF29627_RS01300	COG1214	PFAM Peptidase M22, glycoprotease
CDIF29627_RS01305	COG0456	acetyltransferase
CDIF29627_RS01310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDIF29627_RS01350	COG1473	amidohydrolase
CDIF29627_RS01370	COG0534	Mate efflux family protein
CDIF29627_RS01375	COG0488	(ABC) transporter
CDIF29627_RS01380	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDIF29627_RS01390	COG2221	Nitrite and sulphite reductase 4Fe-4S
CDIF29627_RS01400	COG1151	hydroxylamine reductase activity
CDIF29627_RS01415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDIF29627_RS01455	COG0540	Belongs to the ATCase OTCase family
CDIF29627_RS01460	COG0543	2 iron, 2 sulfur cluster binding
CDIF29627_RS01465	COG0167	dihydroorotate dehydrogenase activity
CDIF29627_RS01470	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDIF29627_RS01480	COG0583	DNA-binding transcription factor activity
CDIF29627_RS01495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDIF29627_RS01500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDIF29627_RS01505	COG0459	protein refolding
CDIF29627_RS01510	COG1691	(AIR) carboxylase
CDIF29627_RS01515	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDIF29627_RS01520	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDIF29627_RS01525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDIF29627_RS01525	COG0519	Catalyzes the synthesis of GMP from XMP
CDIF29627_RS01560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29627_RS01565	COG2771	luxR family
CDIF29627_RS01565	COG2200	EAL domain
CDIF29627_RS01580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS01585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS01595	COG1011	Hydrolase
CDIF29627_RS01610	COG0778	Nitroreductase
CDIF29627_RS01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDIF29627_RS01620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDIF29627_RS01625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDIF29627_RS01630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDIF29627_RS01635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDIF29627_RS01640	COG0138	bifunctional purine biosynthesis protein purh
CDIF29627_RS01645	COG0151	Belongs to the GarS family
CDIF29627_RS01650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDIF29627_RS01655	COG0741	lytic transglycosylase activity
CDIF29627_RS01660	COG1728	Protein conserved in bacteria
CDIF29627_RS01690	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CDIF29627_RS01695	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDIF29627_RS01710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDIF29627_RS01720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDIF29627_RS01725	COG0463	Glycosyl transferase, family 2
CDIF29627_RS01730	COG0560	Phosphoserine phosphatase
CDIF29627_RS01735	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CDIF29627_RS01750	COG4786	Flagellar basal body rod
CDIF29627_RS01760	COG1677	Flagellar hook-basal body complex protein FliE
CDIF29627_RS01765	COG1766	The M ring may be actively involved in energy transduction
CDIF29627_RS01770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDIF29627_RS01780	COG1157	protein secretion by the type III secretion system
CDIF29627_RS01795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDIF29627_RS01800	COG4786	Flagellar basal body rod
CDIF29627_RS01810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDIF29627_RS01815	COG1360	Flagellar Motor Protein
CDIF29627_RS01830	COG1338	Plays a role in the flagellum-specific transport system
CDIF29627_RS01840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDIF29627_RS01845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDIF29627_RS01850	COG1419	protein localization to endoplasmic reticulum
CDIF29627_RS01860	COG1191	sigma factor activity
CDIF29627_RS01875	COG4786	Flagellar basal body rod
CDIF29627_RS01890	COG1776	CheC inhibitor of MCP methylation
CDIF29627_RS01890	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDIF29627_RS01905	COG1454	alcohol dehydrogenase
CDIF29627_RS01910	COG1533	DNA photolyase activity
CDIF29627_RS01925	COG1733	regulation of RNA biosynthetic process
CDIF29627_RS01940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29627_RS01945	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS01945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS01950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS01950	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS01975	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29627_RS01985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS01995	COG3620	sequence-specific DNA binding
CDIF29627_RS02005	COG1131	(ABC) transporter
CDIF29627_RS02025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDIF29627_RS02030	COG1609	Transcriptional regulator
CDIF29627_RS02035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDIF29627_RS02040	COG1879	ABC-type sugar transport system periplasmic component
CDIF29627_RS02045	COG1129	ABC transporter
CDIF29627_RS02050	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDIF29627_RS02055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS02065	COG1473	amidohydrolase
CDIF29627_RS02110	COG2217	Heavy metal translocating P-type atpase
CDIF29627_RS02130	COG0586	Pfam SNARE associated Golgi protein
CDIF29627_RS02160	COG2205	protein histidine kinase activity
CDIF29627_RS02165	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS02190	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CDIF29627_RS02200	COG1122	ATPase activity
CDIF29627_RS02205	COG0210	DNA helicase
CDIF29627_RS02235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDIF29627_RS02250	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29627_RS02250	COG1454	alcohol dehydrogenase
CDIF29627_RS02260	COG1136	(ABC) transporter
CDIF29627_RS02270	COG3290	protein histidine kinase activity
CDIF29627_RS02300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDIF29627_RS02305	COG2357	RelA SpoT domain protein
CDIF29627_RS02325	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CDIF29627_RS02350	COG1263	PTS System
CDIF29627_RS02350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS02350	COG2190	(PTS) system
CDIF29627_RS02355	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS02360	COG3711	transcriptional antiterminator
CDIF29627_RS02365	COG0367	asparagine synthase
CDIF29627_RS02380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDIF29627_RS02405	COG1960	acyl-CoA dehydrogenase activity
CDIF29627_RS02410	COG2086	electron transfer activity
CDIF29627_RS02415	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29627_RS02420	COG3829	transcription factor binding
CDIF29627_RS02425	COG0191	fructose-bisphosphate aldolase activity
CDIF29627_RS02525	COG1388	LysM domain
CDIF29627_RS02525	COG0791	NLP P60 protein
CDIF29627_RS02525	COG3103	Sh3 type 3 domain protein
CDIF29627_RS02540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDIF29627_RS02540	COG0551	DNA topoisomerase type I activity
CDIF29627_RS02595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDIF29627_RS02605	COG3901	Regulator of nitric oxide reductase transcription
CDIF29627_RS02605	COG0348	domain, Protein
CDIF29627_RS02615	COG1136	(ABC) transporter
CDIF29627_RS02630	COG5002	protein histidine kinase activity
CDIF29627_RS02660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDIF29627_RS02675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDIF29627_RS02735	COG3829	transcription factor binding
CDIF29627_RS02740	COG3804	dihydrodipicolinate reductase
CDIF29627_RS02750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDIF29627_RS02760	COG5012	cobalamin binding
CDIF29627_RS02770	COG3457	Alanine racemase
CDIF29627_RS02775	COG1757	Na H antiporter
CDIF29627_RS02795	COG3973	AAA domain
CDIF29627_RS02800	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29627_RS02815	COG1136	(ABC) transporter
CDIF29627_RS02825	COG5002	protein histidine kinase activity
CDIF29627_RS02830	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS02835	COG1309	transcriptional regulator
CDIF29627_RS02850	COG1131	(ABC) transporter
CDIF29627_RS02865	COG1737	Transcriptional regulator
CDIF29627_RS02875	COG0561	phosphatase activity
CDIF29627_RS02880	COG0366	Alpha amylase catalytic
CDIF29627_RS02900	COG0768	penicillin binding
CDIF29627_RS02915	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDIF29627_RS02945	COG1131	(ABC) transporter
CDIF29627_RS02965	COG5002	protein histidine kinase activity
CDIF29627_RS02975	COG1136	(ABC) transporter
CDIF29627_RS02980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDIF29627_RS02990	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS03070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDIF29627_RS03085	COG1063	alcohol dehydrogenase
CDIF29627_RS03095	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS03105	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29627_RS03125	COG1686	Belongs to the peptidase S11 family
CDIF29627_RS03130	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS03130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS03150	COG2205	protein histidine kinase activity
CDIF29627_RS03175	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29627_RS03180	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDIF29627_RS03205	COG2378	regulation of single-species biofilm formation
CDIF29627_RS03220	COG2201	protein-glutamate methylesterase activity
CDIF29627_RS03225	COG1776	CheC inhibitor of MCP methylation
CDIF29627_RS03230	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDIF29627_RS03235	COG0835	chemotaxis
CDIF29627_RS03245	COG0840	transmembrane signaling receptor activity
CDIF29627_RS03250	COG0643	Histidine kinase
CDIF29627_RS03250	COG2198	Histidine kinase
CDIF29627_RS03255	COG0835	chemotaxis
CDIF29627_RS03265	COG2201	protein-glutamate methylesterase activity
CDIF29627_RS03315	COG2339	peptidase activity
CDIF29627_RS03320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDIF29627_RS03320	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CDIF29627_RS03325	COG0681	Belongs to the peptidase S26 family
CDIF29627_RS03340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDIF29627_RS03350	COG2066	Belongs to the glutaminase family
CDIF29627_RS03360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDIF29627_RS03380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDIF29627_RS03385	COG1067	ATP-dependent peptidase activity
CDIF29627_RS03390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDIF29627_RS03395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDIF29627_RS03405	COG1744	ABC transporter substrate-binding protein PnrA-like
CDIF29627_RS03430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDIF29627_RS03485	COG1309	transcriptional regulator
CDIF29627_RS03490	COG3848	Pyruvate phosphate dikinase
CDIF29627_RS03490	COG0574	Belongs to the PEP-utilizing enzyme family
CDIF29627_RS03505	COG3706	GGDEF domain
CDIF29627_RS03585	COG3969	phosphoadenosine phosphosulfate
CDIF29627_RS03590	COG1475	DNA binding
CDIF29627_RS03605	COG3546	catalase activity
CDIF29627_RS03620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDIF29627_RS03635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDIF29627_RS03660	COG3279	Response regulator of the LytR AlgR family
CDIF29627_RS03665	COG0577	efflux transmembrane transporter activity
CDIF29627_RS03670	COG1136	(ABC) transporter
CDIF29627_RS03690	COG0789	Transcriptional regulator
CDIF29627_RS03690	COG4978	Transcriptional regulator
CDIF29627_RS03740	COG0305	Participates in initiation and elongation during chromosome replication
CDIF29627_RS03760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDIF29627_RS03765	COG0534	Mate efflux family protein
CDIF29627_RS03775	COG4335	DNA alkylation repair
CDIF29627_RS03830	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS03835	COG2205	protein histidine kinase activity
CDIF29627_RS03840	COG1131	(ABC) transporter
CDIF29627_RS03850	COG3177	Filamentation induced by cAMP protein fic
CDIF29627_RS03855	COG1802	Transcriptional regulator
CDIF29627_RS03860	COG0823	Involved in the tonB-independent uptake of proteins
CDIF29627_RS03860	COG1506	peptidase
CDIF29627_RS03860	COG4946	Tricorn protease homolog
CDIF29627_RS03865	COG4946	Tricorn protease homolog
CDIF29627_RS03865	COG1506	peptidase
CDIF29627_RS03865	COG0823	Involved in the tonB-independent uptake of proteins
CDIF29627_RS03880	COG1737	Transcriptional regulator
CDIF29627_RS03885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS03890	COG0383	alpha-mannosidase activity
CDIF29627_RS03895	COG0366	Alpha amylase catalytic
CDIF29627_RS03935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDIF29627_RS03945	COG1136	(ABC) transporter
CDIF29627_RS03950	COG1132	(ABC) transporter
CDIF29627_RS03955	COG2801	Transposase and inactivated derivatives
CDIF29627_RS03970	COG0038	chloride channel
CDIF29627_RS04075	COG2205	protein histidine kinase activity
CDIF29627_RS04115	COG1595	DNA-templated transcription, initiation
CDIF29627_RS04130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDIF29627_RS04165	COG2814	Major facilitator Superfamily
CDIF29627_RS04170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDIF29627_RS04175	COG1609	Transcriptional regulator
CDIF29627_RS04190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDIF29627_RS04195	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDIF29627_RS04240	COG0789	Transcriptional regulator
CDIF29627_RS04260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDIF29627_RS04265	COG0569	domain protein
CDIF29627_RS04270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDIF29627_RS04275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDIF29627_RS04280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29627_RS04280	COG0072	phenylalanine-tRNA ligase activity
CDIF29627_RS04295	COG0826	peptidase U32
CDIF29627_RS04305	COG1051	belongs to the nudix hydrolase family
CDIF29627_RS04315	COG3706	GGDEF domain
CDIF29627_RS04320	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29627_RS04325	COG1193	negative regulation of DNA recombination
CDIF29627_RS04330	COG1683	Conserved Protein
CDIF29627_RS04335	COG0018	arginyl-trna synthetase
CDIF29627_RS04350	COG1032	radical SAM domain protein
CDIF29627_RS04360	COG0583	DNA-binding transcription factor activity
CDIF29627_RS04370	COG0280	phosphate acetyltransferase
CDIF29627_RS04375	COG1151	hydroxylamine reductase activity
CDIF29627_RS04385	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDIF29627_RS04390	COG3404	Formiminotransferase-cyclodeaminase
CDIF29627_RS04395	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDIF29627_RS04405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDIF29627_RS04405	COG0646	methionine synthase
CDIF29627_RS04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDIF29627_RS04440	COG0509	glycine decarboxylation via glycine cleavage system
CDIF29627_RS04460	COG0095	Lipoate-protein ligase
CDIF29627_RS04480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29627_RS04495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDIF29627_RS04495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29627_RS04505	COG3192	ethanolamine utilization protein
CDIF29627_RS04510	COG1349	DNA-binding transcription factor activity
CDIF29627_RS04520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDIF29627_RS04525	COG1360	Flagellar Motor Protein
CDIF29627_RS04545	COG0210	DNA helicase
CDIF29627_RS04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDIF29627_RS04555	COG0765	amino acid transport
CDIF29627_RS04560	COG1126	abc transporter atp-binding protein
CDIF29627_RS04570	COG0301	tRNA thio-modification
CDIF29627_RS04580	COG0778	Nitroreductase
CDIF29627_RS04585	COG5001	Diguanylate cyclase
CDIF29627_RS04585	COG3300	MHYT domain
CDIF29627_RS04590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDIF29627_RS04600	COG0530	calcium, potassium:sodium antiporter activity
CDIF29627_RS04605	COG0513	Belongs to the DEAD box helicase family
CDIF29627_RS04610	COG0243	molybdopterin cofactor binding
CDIF29627_RS04615	COG1366	Belongs to the anti-sigma-factor antagonist family
CDIF29627_RS04620	COG2172	sigma factor antagonist activity
CDIF29627_RS04625	COG1191	sigma factor activity
CDIF29627_RS04635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDIF29627_RS04660	COG1473	amidohydrolase
CDIF29627_RS04670	COG2226	methyltransferase
CDIF29627_RS04685	COG0295	cytidine deaminase activity
CDIF29627_RS04690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDIF29627_RS04700	COG0750	zinc metalloprotease
CDIF29627_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS04710	COG0488	(ABC) transporter
CDIF29627_RS04725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDIF29627_RS04740	COG1739	Uncharacterized protein family UPF0029
CDIF29627_RS04750	COG0730	response to heat
CDIF29627_RS04755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDIF29627_RS04760	COG0217	transcriptional regulatory protein
CDIF29627_RS04765	COG1024	Enoyl-CoA hydratase
CDIF29627_RS04770	COG2610	gluconate transmembrane transporter activity
CDIF29627_RS04785	COG2086	electron transfer activity
CDIF29627_RS04790	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29627_RS04820	COG3300	MHYT domain
CDIF29627_RS04820	COG5001	Diguanylate cyclase
CDIF29627_RS04835	COG2186	Transcriptional regulator
CDIF29627_RS04840	COG2814	Major facilitator Superfamily
CDIF29627_RS04845	COG1263	PTS System
CDIF29627_RS04845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS04845	COG2190	(PTS) system
CDIF29627_RS04850	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS04860	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS04865	COG5002	protein histidine kinase activity
CDIF29627_RS04885	COG1592	Rubrerythrin
CDIF29627_RS04895	COG2033	superoxide reductase activity
CDIF29627_RS04900	COG0069	glutamate synthase activity
CDIF29627_RS04920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDIF29627_RS04930	COG0473	3-isopropylmalate dehydrogenase activity
CDIF29627_RS04935	COG1846	Transcriptional regulator
CDIF29627_RS04960	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDIF29627_RS04965	COG0138	bifunctional purine biosynthesis protein purh
CDIF29627_RS04975	COG0297	glycogen (starch) synthase activity
CDIF29627_RS04975	COG0438	transferase activity, transferring glycosyl groups
CDIF29627_RS04990	COG3620	sequence-specific DNA binding
CDIF29627_RS05020	COG1473	amidohydrolase
CDIF29627_RS05025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDIF29627_RS05040	COG0601	transmembrane transport
CDIF29627_RS05045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDIF29627_RS05055	COG0444	Belongs to the ABC transporter superfamily
CDIF29627_RS05060	COG4608	Belongs to the ABC transporter superfamily
CDIF29627_RS05065	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS05065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS05080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS05090	COG1486	melibiose metabolic process
CDIF29627_RS05100	COG1073	alpha beta
CDIF29627_RS05110	COG1910	domain protein
CDIF29627_RS05115	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDIF29627_RS05120	COG4149	molybdate abc transporter
CDIF29627_RS05125	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDIF29627_RS05130	COG0110	maltose O-acetyltransferase activity
CDIF29627_RS05140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDIF29627_RS05145	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDIF29627_RS05150	COG2984	ABC transporter substrate binding protein
CDIF29627_RS05160	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDIF29627_RS05165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDIF29627_RS05165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDIF29627_RS05180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDIF29627_RS05185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDIF29627_RS05190	COG0297	glycogen (starch) synthase activity
CDIF29627_RS05195	COG0058	SHG alpha-glucan phosphorylase activity
CDIF29627_RS05205	COG1802	Transcriptional regulator
CDIF29627_RS05215	COG1982	Orn Lys Arg decarboxylase major
CDIF29627_RS05220	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDIF29627_RS05225	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDIF29627_RS05230	COG0010	Belongs to the arginase family
CDIF29627_RS05265	COG4868	Belongs to the UPF0371 family
CDIF29627_RS05270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDIF29627_RS05280	COG1174	glycine betaine transport
CDIF29627_RS05285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDIF29627_RS05315	COG0534	Mate efflux family protein
CDIF29627_RS05320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDIF29627_RS05320	COG0539	negative regulation of cytoplasmic translation
CDIF29627_RS05325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29627_RS05335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDIF29627_RS05340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDIF29627_RS05345	COG0066	3-isopropylmalate dehydratase activity
CDIF29627_RS05350	COG0473	3-isopropylmalate dehydrogenase activity
CDIF29627_RS05365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDIF29627_RS05380	COG5001	Diguanylate cyclase
CDIF29627_RS05380	COG5002	protein histidine kinase activity
CDIF29627_RS05380	COG3447	MASE1 domain protein
CDIF29627_RS05405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDIF29627_RS05410	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDIF29627_RS05420	COG0281	malic enzyme
CDIF29627_RS05430	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS05435	COG5002	protein histidine kinase activity
CDIF29627_RS05440	COG1136	(ABC) transporter
CDIF29627_RS05440	COG0577	efflux transmembrane transporter activity
CDIF29627_RS05460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDIF29627_RS05465	COG0363	glucosamine-6-phosphate deaminase activity
CDIF29627_RS05480	COG5002	protein histidine kinase activity
CDIF29627_RS05485	COG5001	Diguanylate cyclase
CDIF29627_RS05495	COG0789	Transcriptional regulator
CDIF29627_RS05495	COG4978	Transcriptional regulator
CDIF29627_RS05505	COG1132	(ABC) transporter
CDIF29627_RS05525	COG2364	Membrane
CDIF29627_RS05535	COG3842	ATPase activity
CDIF29627_RS05540	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDIF29627_RS05545	COG1177	transmembrane transport
CDIF29627_RS05550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDIF29627_RS05560	COG5298	Protein conserved in bacteria
CDIF29627_RS05565	COG1215	transferase activity, transferring glycosyl groups
CDIF29627_RS05580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDIF29627_RS05610	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS05615	COG2247	cell wall binding repeat
CDIF29627_RS05615	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS05625	COG0210	DNA helicase
CDIF29627_RS05635	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CDIF29627_RS05640	COG1074	ATP-dependent DNA helicase activity
CDIF29627_RS05645	COG0420	3'-5' exonuclease activity
CDIF29627_RS05650	COG0419	ATPase involved in DNA repair
CDIF29627_RS05655	COG4536	flavin adenine dinucleotide binding
CDIF29627_RS05665	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29627_RS05675	COG0622	Phosphoesterase
CDIF29627_RS05680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDIF29627_RS05685	COG1131	(ABC) transporter
CDIF29627_RS05705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDIF29627_RS05710	COG1960	acyl-CoA dehydrogenase activity
CDIF29627_RS05715	COG2086	electron transfer activity
CDIF29627_RS05720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29627_RS05735	COG0183	Belongs to the thiolase family
CDIF29627_RS05740	COG0564	pseudouridine synthase activity
CDIF29627_RS05750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDIF29627_RS05805	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29627_RS05810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS05815	COG4224	UPF0291 protein
CDIF29627_RS05820	COG1362	aminopeptidase activity
CDIF29627_RS05825	COG2188	Transcriptional regulator
CDIF29627_RS05845	COG3715	PTS system
CDIF29627_RS05850	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29627_RS05855	COG0583	DNA-binding transcription factor activity
CDIF29627_RS05875	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29627_RS05880	COG1132	(ABC) transporter
CDIF29627_RS05890	COG1473	amidohydrolase
CDIF29627_RS05905	COG3279	Response regulator of the LytR AlgR family
CDIF29627_RS05920	COG1882	Formate acetyltransferase
CDIF29627_RS05925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDIF29627_RS05930	COG1396	sequence-specific DNA binding
CDIF29627_RS05955	COG3708	Transcriptional regulator
CDIF29627_RS05955	COG2207	Transcriptional regulator
CDIF29627_RS05995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDIF29627_RS05995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDIF29627_RS06000	COG0237	dephospho-CoA kinase activity
CDIF29627_RS06025	COG0346	lactoylglutathione lyase activity
CDIF29627_RS06030	COG0791	NLP P60 protein
CDIF29627_RS06040	COG4656	Part of a membrane complex involved in electron transport
CDIF29627_RS06045	COG4658	electron transport chain
CDIF29627_RS06050	COG4659	FMN binding
CDIF29627_RS06055	COG4660	Part of a membrane complex involved in electron transport
CDIF29627_RS06060	COG4657	Part of a membrane complex involved in electron transport
CDIF29627_RS06065	COG2878	Part of a membrane complex involved in electron transport
CDIF29627_RS06065	COG1245	4Fe-4S binding domain
CDIF29627_RS06070	COG0424	maF-like protein
CDIF29627_RS06075	COG2003	Belongs to the UPF0758 family
CDIF29627_RS06080	COG1077	Cell shape determining protein MreB Mrl
CDIF29627_RS06100	COG0850	regulation of cytokinetic process
CDIF29627_RS06105	COG2894	cell division
CDIF29627_RS06110	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDIF29627_RS06115	COG0772	Belongs to the SEDS family
CDIF29627_RS06120	COG1803	Methylglyoxal synthase
CDIF29627_RS06130	COG0426	domain, Protein
CDIF29627_RS06150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDIF29627_RS06160	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDIF29627_RS06165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDIF29627_RS06175	COG0460	homoserine dehydrogenase
CDIF29627_RS06185	COG3314	Sporulation integral membrane protein YlbJ
CDIF29627_RS06190	COG2186	Transcriptional regulator
CDIF29627_RS06195	COG3875	lactate racemase activity
CDIF29627_RS06200	COG2086	electron transfer activity
CDIF29627_RS06210	COG0277	FAD linked oxidase domain protein
CDIF29627_RS06215	COG1323	Belongs to the UPF0348 family
CDIF29627_RS06220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDIF29627_RS06230	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDIF29627_RS06240	COG0416	fatty acid biosynthetic process
CDIF29627_RS06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDIF29627_RS06255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDIF29627_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29627_RS06265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDIF29627_RS06270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDIF29627_RS06275	COG3706	GGDEF domain
CDIF29627_RS06290	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDIF29627_RS06305	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CDIF29627_RS06310	COG3854	ATPases associated with a variety of cellular activities
CDIF29627_RS06350	COG1302	Protein conserved in bacteria
CDIF29627_RS06355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDIF29627_RS06360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDIF29627_RS06365	COG1570	exodeoxyribonuclease VII activity
CDIF29627_RS06380	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CDIF29627_RS06385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDIF29627_RS06390	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDIF29627_RS06395	COG0497	DNA recombination
CDIF29627_RS06405	COG0456	acetyltransferase
CDIF29627_RS06410	COG0456	acetyltransferase
CDIF29627_RS06415	COG0750	zinc metalloprotease
CDIF29627_RS06435	COG0463	Glycosyl transferase, family 2
CDIF29627_RS06450	COG0494	nUDIX hydrolase
CDIF29627_RS06460	COG4974	Belongs to the 'phage' integrase family
CDIF29627_RS06465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDIF29627_RS06480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDIF29627_RS06485	COG4122	O-methyltransferase activity
CDIF29627_RS06490	COG0826	peptidase U32
CDIF29627_RS06495	COG0768	penicillin binding
CDIF29627_RS06645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDIF29627_RS06655	COG0571	ribonuclease III activity
CDIF29627_RS06665	COG1196	nuclear chromosome segregation
CDIF29627_RS06670	COG0552	protein localization to endoplasmic reticulum
CDIF29627_RS06680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDIF29627_RS06685	COG0228	four-way junction DNA binding
CDIF29627_RS06695	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDIF29627_RS06700	COG0336	Belongs to the RNA methyltransferase TrmD family
CDIF29627_RS06705	COG0335	large ribosomal subunit rRNA binding
CDIF29627_RS06715	COG1114	Component of the transport system for branched-chain amino acids
CDIF29627_RS06730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDIF29627_RS06760	COG1131	(ABC) transporter
CDIF29627_RS06765	COG2197	response regulator
CDIF29627_RS06770	COG4585	Histidine kinase
CDIF29627_RS06775	COG0792	nuclease activity
CDIF29627_RS06780	COG0606	chelatase, subunit chli
CDIF29627_RS06785	COG0758	DNA mediated transformation
CDIF29627_RS06790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDIF29627_RS06800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDIF29627_RS06810	COG1959	2 iron, 2 sulfur cluster binding
CDIF29627_RS06820	COG0822	iron-sulfur transferase activity
CDIF29627_RS06825	COG0482	sulfurtransferase activity
CDIF29627_RS06830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDIF29627_RS06835	COG4472	Bacterial protein of unknown function (DUF965)
CDIF29627_RS06845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDIF29627_RS06850	COG3906	Belongs to the UPF0473 family
CDIF29627_RS06855	COG0735	belongs to the Fur family
CDIF29627_RS06865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDIF29627_RS06875	COG1686	Belongs to the peptidase S11 family
CDIF29627_RS06885	COG2207	Transcriptional regulator
CDIF29627_RS06885	COG1917	Cupin 2, conserved barrel domain protein
CDIF29627_RS06890	COG1994	Peptidase M50
CDIF29627_RS06900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDIF29627_RS06955	COG0779	Required for maturation of 30S ribosomal subunits
CDIF29627_RS06960	COG0195	Participates in both transcription termination and antitermination
CDIF29627_RS06965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CDIF29627_RS06975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDIF29627_RS06985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDIF29627_RS06990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDIF29627_RS06995	COG0196	riboflavin kinase activity
CDIF29627_RS07005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDIF29627_RS07010	COG1307	EDD domain protein, DegV family
CDIF29627_RS07015	COG1185	polyribonucleotide nucleotidyltransferase activity
CDIF29627_RS07020	COG0726	polysaccharide deacetylase
CDIF29627_RS07025	COG0612	Peptidase, M16
CDIF29627_RS07030	COG1873	PFAM PRC-barrel domain
CDIF29627_RS07035	COG0527	aspartate kinase activity
CDIF29627_RS07040	COG0740	serine-type endopeptidase activity
CDIF29627_RS07050	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CDIF29627_RS07055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29627_RS07065	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDIF29627_RS07070	COG1418	mRNA catabolic process
CDIF29627_RS07085	COG1968	undecaprenyl-diphosphatase activity
CDIF29627_RS07095	COG0114	fumarate hydratase activity
CDIF29627_RS07105	COG1263	PTS System
CDIF29627_RS07105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS07115	COG1486	melibiose metabolic process
CDIF29627_RS07120	COG0436	Aminotransferase
CDIF29627_RS07130	COG0708	Exodeoxyribonuclease III
CDIF29627_RS07145	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29627_RS07170	COG1131	(ABC) transporter
CDIF29627_RS07200	COG1278	Cold shock
CDIF29627_RS07210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDIF29627_RS07290	COG3299	homolog of phage Mu protein gp47
CDIF29627_RS07295	COG3778	Protein conserved in bacteria
CDIF29627_RS07340	COG1396	sequence-specific DNA binding
CDIF29627_RS07345	COG2814	Major facilitator Superfamily
CDIF29627_RS07355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDIF29627_RS07360	COG3273	potassium ion transport
CDIF29627_RS07360	COG0471	metal ion transport
CDIF29627_RS07365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDIF29627_RS07370	COG1914	H( )-stimulated, divalent metal cation uptake system
CDIF29627_RS07375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDIF29627_RS07380	COG1984	allophanate hydrolase subunit 2
CDIF29627_RS07385	COG1396	sequence-specific DNA binding
CDIF29627_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
CDIF29627_RS07445	COG1473	amidohydrolase
CDIF29627_RS07450	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDIF29627_RS07465	COG0584	glycerophosphoryl diester phosphodiesterase
CDIF29627_RS07485	COG0488	(ABC) transporter
CDIF29627_RS07495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS07500	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDIF29627_RS07505	COG1058	Belongs to the CinA family
CDIF29627_RS07505	COG1546	Belongs to the CinA family
CDIF29627_RS07520	COG3829	transcription factor binding
CDIF29627_RS07530	COG1242	4 iron, 4 sulfur cluster binding
CDIF29627_RS07565	COG2801	Transposase and inactivated derivatives
CDIF29627_RS07570	COG5002	protein histidine kinase activity
CDIF29627_RS07570	COG5001	Diguanylate cyclase
CDIF29627_RS07570	COG3447	MASE1 domain protein
CDIF29627_RS07575	COG2199	diguanylate cyclase activity
CDIF29627_RS07575	COG2203	Gaf domain
CDIF29627_RS07585	COG0789	Transcriptional regulator
CDIF29627_RS07585	COG4978	Transcriptional regulator
CDIF29627_RS07600	COG1285	pathogenesis
CDIF29627_RS07605	COG1335	isochorismatase
CDIF29627_RS07625	COG0726	polysaccharide deacetylase
CDIF29627_RS07640	COG0450	alkyl hydroperoxide reductase
CDIF29627_RS07655	COG2720	vancomycin resistance protein
CDIF29627_RS07660	COG3829	transcription factor binding
CDIF29627_RS07675	COG1346	cytolysis
CDIF29627_RS07680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29627_RS07690	COG2340	Cysteine-rich secretory protein family
CDIF29627_RS07695	COG0726	polysaccharide deacetylase
CDIF29627_RS07700	COG0512	Glutamine amidotransferase of anthranilate synthase
CDIF29627_RS07705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDIF29627_RS07720	COG0302	gtp cyclohydrolase
CDIF29627_RS07725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDIF29627_RS07730	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDIF29627_RS07735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDIF29627_RS07740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDIF29627_RS07745	COG0358	DNA primase activity
CDIF29627_RS07750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDIF29627_RS07755	COG2384	SAM-dependent methyltransferase
CDIF29627_RS07760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDIF29627_RS07765	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDIF29627_RS07785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS07795	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS07800	COG5002	protein histidine kinase activity
CDIF29627_RS07800	COG3850	Histidine kinase
CDIF29627_RS07805	COG1136	(ABC) transporter
CDIF29627_RS07805	COG0577	efflux transmembrane transporter activity
CDIF29627_RS07835	COG1132	(ABC) transporter
CDIF29627_RS07840	COG1132	(ABC) transporter
CDIF29627_RS07845	COG1773	rubredoxin
CDIF29627_RS07845	COG1592	Rubrerythrin
CDIF29627_RS07855	COG0412	Dienelactone hydrolase
CDIF29627_RS07890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29627_RS07925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDIF29627_RS07930	COG2011	ABC-type metal ion transport system permease component
CDIF29627_RS07940	COG5002	protein histidine kinase activity
CDIF29627_RS07945	COG2094	Belongs to the DNA glycosylase MPG family
CDIF29627_RS07950	COG1396	sequence-specific DNA binding
CDIF29627_RS07955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDIF29627_RS07960	COG4086	secreted protein
CDIF29627_RS07980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDIF29627_RS07990	COG1131	(ABC) transporter
CDIF29627_RS08000	COG0534	Mate efflux family protein
CDIF29627_RS08015	COG0348	domain, Protein
CDIF29627_RS08015	COG3901	Regulator of nitric oxide reductase transcription
CDIF29627_RS08040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDIF29627_RS08045	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDIF29627_RS08055	COG5001	Diguanylate cyclase
CDIF29627_RS08065	COG0789	Transcriptional regulator
CDIF29627_RS08065	COG4978	Transcriptional regulator
CDIF29627_RS08070	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CDIF29627_RS08090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDIF29627_RS08095	COG0726	polysaccharide deacetylase
CDIF29627_RS08105	COG1773	rubredoxin
CDIF29627_RS08105	COG1592	Rubrerythrin
CDIF29627_RS08110	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29627_RS08115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDIF29627_RS08120	COG0577	efflux transmembrane transporter activity
CDIF29627_RS08125	COG1136	(ABC) transporter
CDIF29627_RS08135	COG2205	protein histidine kinase activity
CDIF29627_RS08140	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS08145	COG1136	(ABC) transporter
CDIF29627_RS08150	COG0577	efflux transmembrane transporter activity
CDIF29627_RS08155	COG0405	Gamma-glutamyltransferase
CDIF29627_RS08170	COG0493	'glutamate synthase
CDIF29627_RS08170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29627_RS08180	COG1136	(ABC) transporter
CDIF29627_RS08185	COG0577	efflux transmembrane transporter activity
CDIF29627_RS08225	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDIF29627_RS08230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDIF29627_RS08235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29627_RS08240	COG0131	Imidazoleglycerol-phosphate dehydratase
CDIF29627_RS08245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDIF29627_RS08250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDIF29627_RS08255	COG0107	imidazoleglycerol-phosphate synthase activity
CDIF29627_RS08260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDIF29627_RS08260	COG0140	phosphoribosyl-ATP diphosphatase activity
CDIF29627_RS08265	COG0531	amino acid
CDIF29627_RS08280	COG1595	DNA-templated transcription, initiation
CDIF29627_RS08295	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDIF29627_RS08310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDIF29627_RS08315	COG0028	Belongs to the TPP enzyme family
CDIF29627_RS08320	COG0582	viral genome integration into host DNA
CDIF29627_RS08350	COG3617	BRO family, N-terminal domain
CDIF29627_RS08365	COG1476	TRANSCRIPTIONal
CDIF29627_RS08445	COG5484	DNA packaging
CDIF29627_RS08455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29627_RS08565	COG4193	domain, Protein
CDIF29627_RS08575	COG3628	GPW Gp25 family protein
CDIF29627_RS08580	COG3299	homolog of phage Mu protein gp47
CDIF29627_RS08625	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS08625	COG1388	LysM domain
CDIF29627_RS08640	COG3546	catalase activity
CDIF29627_RS08645	COG1331	Highly conserved protein containing a thioredoxin domain
CDIF29627_RS08655	COG2267	carboxylic ester hydrolase activity
CDIF29627_RS08660	COG1136	(ABC) transporter
CDIF29627_RS08680	COG3584	3D domain protein
CDIF29627_RS08680	COG1388	LysM domain
CDIF29627_RS08690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29627_RS08695	COG1295	ribonuclease BN
CDIF29627_RS08700	COG5002	protein histidine kinase activity
CDIF29627_RS08705	COG0460	homoserine dehydrogenase
CDIF29627_RS08715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDIF29627_RS08720	COG2267	carboxylic ester hydrolase activity
CDIF29627_RS08725	COG5566	PFAM Mor transcription activator
CDIF29627_RS08735	COG2971	BadF BadG BcrA BcrD
CDIF29627_RS08745	COG1129	ABC transporter
CDIF29627_RS08750	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDIF29627_RS08760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29627_RS08770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDIF29627_RS08775	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDIF29627_RS08780	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CDIF29627_RS08785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDIF29627_RS08790	COG1045	serine acetyltransferase
CDIF29627_RS08795	COG1141	Ferredoxin
CDIF29627_RS08815	COG0351	phosphomethylpyrimidine kinase
CDIF29627_RS08815	COG0352	thiamine-phosphate diphosphorylase activity
CDIF29627_RS08820	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CDIF29627_RS08825	COG0352	thiamine-phosphate diphosphorylase activity
CDIF29627_RS08830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS08850	COG1725	Transcriptional regulator
CDIF29627_RS08880	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29627_RS08890	COG4555	ABC transporter
CDIF29627_RS08895	COG1668	transmembrane transport
CDIF29627_RS08900	COG5001	Diguanylate cyclase
CDIF29627_RS08900	COG3300	MHYT domain
CDIF29627_RS08905	COG1725	Transcriptional regulator
CDIF29627_RS08910	COG1131	(ABC) transporter
CDIF29627_RS08925	COG0668	transmembrane transport
CDIF29627_RS08935	COG0426	domain, Protein
CDIF29627_RS08955	COG0367	asparagine synthase
CDIF29627_RS08960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDIF29627_RS08975	COG2310	stress, protein
CDIF29627_RS08990	COG3853	Toxic anion resistance protein (TelA)
CDIF29627_RS09020	COG5505	Protein of unknown function (DUF819)
CDIF29627_RS09030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29627_RS09035	COG4605	iron ion homeostasis
CDIF29627_RS09040	COG4604	ABC transporter, ATP-binding protein
CDIF29627_RS09045	COG4607	ABC-type enterochelin transport system periplasmic component
CDIF29627_RS09050	COG2203	Gaf domain
CDIF29627_RS09050	COG3706	GGDEF domain
CDIF29627_RS09050	COG4251	negative regulation of phosphorylation
CDIF29627_RS09050	COG5001	Diguanylate cyclase
CDIF29627_RS09065	COG0095	Lipoate-protein ligase
CDIF29627_RS09070	COG1757	Na H antiporter
CDIF29627_RS09085	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDIF29627_RS09090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDIF29627_RS09095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDIF29627_RS09100	COG3123	guanosine phosphorylase activity
CDIF29627_RS09105	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29627_RS09120	COG1396	sequence-specific DNA binding
CDIF29627_RS09130	COG0584	glycerophosphoryl diester phosphodiesterase
CDIF29627_RS09135	COG0110	maltose O-acetyltransferase activity
CDIF29627_RS09150	COG1131	(ABC) transporter
CDIF29627_RS09160	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS09165	COG2205	protein histidine kinase activity
CDIF29627_RS09185	COG1733	regulation of RNA biosynthetic process
CDIF29627_RS09190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CDIF29627_RS09220	COG1309	transcriptional regulator
CDIF29627_RS09255	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS09260	COG5002	protein histidine kinase activity
CDIF29627_RS09265	COG3118	belongs to the thioredoxin family
CDIF29627_RS09295	COG1115	amino acid carrier protein
CDIF29627_RS09305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDIF29627_RS09305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDIF29627_RS09320	COG0514	ATP-dependent DNA helicase (RecQ)
CDIF29627_RS09325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDIF29627_RS09340	COG2022	thiamine diphosphate biosynthetic process
CDIF29627_RS09345	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDIF29627_RS09355	COG1288	antiporter activity
CDIF29627_RS09375	COG0393	Putative heavy-metal-binding
CDIF29627_RS09380	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDIF29627_RS09390	COG0315	cyclic pyranopterin monophosphate synthase activity
CDIF29627_RS09465	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDIF29627_RS09490	COG5012	cobalamin binding
CDIF29627_RS09495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDIF29627_RS09505	COG1011	Hydrolase
CDIF29627_RS09510	COG1396	sequence-specific DNA binding
CDIF29627_RS09510	COG1917	Cupin 2, conserved barrel domain protein
CDIF29627_RS09515	COG2610	gluconate transmembrane transporter activity
CDIF29627_RS09520	COG5002	protein histidine kinase activity
CDIF29627_RS09525	COG2204	response regulator
CDIF29627_RS09565	COG0786	glutamate:sodium symporter activity
CDIF29627_RS09580	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CDIF29627_RS09585	COG1924	4 iron, 4 sulfur cluster binding
CDIF29627_RS09590	COG2385	sporulation resulting in formation of a cellular spore
CDIF29627_RS09590	COG2247	cell wall binding repeat
CDIF29627_RS09600	COG1309	transcriptional regulator
CDIF29627_RS09625	COG0242	peptide deformylase activity
CDIF29627_RS09665	COG3326	Membrane
CDIF29627_RS09680	COG0494	nUDIX hydrolase
CDIF29627_RS09730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDIF29627_RS09735	COG0765	amino acid transport
CDIF29627_RS09745	COG1393	Belongs to the ArsC family
CDIF29627_RS09755	COG1606	tRNA processing
CDIF29627_RS09760	COG0116	Belongs to the methyltransferase superfamily
CDIF29627_RS09775	COG5002	protein histidine kinase activity
CDIF29627_RS09775	COG3850	Histidine kinase
CDIF29627_RS09785	COG0137	argininosuccinate synthase activity
CDIF29627_RS09795	COG0789	Transcriptional regulator
CDIF29627_RS09805	COG2323	membrane
CDIF29627_RS09820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDIF29627_RS09845	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDIF29627_RS09850	COG0583	DNA-binding transcription factor activity
CDIF29627_RS09865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29627_RS09880	COG1609	Transcriptional regulator
CDIF29627_RS09890	COG1621	beta-fructofuranosidase activity
CDIF29627_RS09895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDIF29627_RS09910	COG2814	Major facilitator Superfamily
CDIF29627_RS09940	COG0406	alpha-ribazole phosphatase activity
CDIF29627_RS09945	COG2081	HI0933 family
CDIF29627_RS09950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDIF29627_RS09955	COG0204	Acyl-transferase
CDIF29627_RS09960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDIF29627_RS09985	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDIF29627_RS09990	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDIF29627_RS09995	COG3022	response to hydroperoxide
CDIF29627_RS10010	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDIF29627_RS10015	COG1846	Transcriptional regulator
CDIF29627_RS10020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDIF29627_RS10025	COG2205	protein histidine kinase activity
CDIF29627_RS10035	COG0598	Magnesium transport protein CorA
CDIF29627_RS10045	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDIF29627_RS10055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDIF29627_RS10060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDIF29627_RS10065	COG1605	Chorismate mutase
CDIF29627_RS10065	COG0077	Prephenate dehydratase
CDIF29627_RS10070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDIF29627_RS10080	COG0287	Prephenate dehydrogenase
CDIF29627_RS10090	COG3706	GGDEF domain
CDIF29627_RS10125	COG3708	Transcriptional regulator
CDIF29627_RS10125	COG2207	Transcriptional regulator
CDIF29627_RS10165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDIF29627_RS10170	COG2226	methyltransferase
CDIF29627_RS10175	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CDIF29627_RS10205	COG2131	deaminase
CDIF29627_RS10235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29627_RS10285	COG4303	Ethanolamine ammonia lyase large subunit
CDIF29627_RS10290	COG4302	ethanolamine ammonia-lyase activity
CDIF29627_RS10305	COG1454	alcohol dehydrogenase
CDIF29627_RS10305	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29627_RS10320	COG4869	propanediol catabolic process
CDIF29627_RS10330	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CDIF29627_RS10340	COG3192	ethanolamine utilization protein
CDIF29627_RS10345	COG4766	ethanolamine catabolic process
CDIF29627_RS10350	COG2207	Transcriptional regulator
CDIF29627_RS10370	COG1473	amidohydrolase
CDIF29627_RS10375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDIF29627_RS10380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29627_RS10385	COG1116	anion transmembrane transporter activity
CDIF29627_RS10405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDIF29627_RS10410	COG4974	Belongs to the 'phage' integrase family
CDIF29627_RS10425	COG2359	stage V sporulation protein S
CDIF29627_RS10430	COG0825	malonyl-CoA metabolic process
CDIF29627_RS10435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDIF29627_RS10440	COG0439	Biotin carboxylase
CDIF29627_RS10445	COG0511	ligase activity, forming carbon-carbon bonds
CDIF29627_RS10465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDIF29627_RS10490	COG1136	(ABC) transporter
CDIF29627_RS10500	COG2205	protein histidine kinase activity
CDIF29627_RS10505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29627_RS10510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDIF29627_RS10530	COG1136	(ABC) transporter
CDIF29627_RS10530	COG0577	efflux transmembrane transporter activity
CDIF29627_RS10535	COG2205	protein histidine kinase activity
CDIF29627_RS10540	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS10550	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS10555	COG5002	protein histidine kinase activity
CDIF29627_RS10560	COG0577	efflux transmembrane transporter activity
CDIF29627_RS10560	COG1136	(ABC) transporter
CDIF29627_RS10595	COG1811	Na channel or pump
CDIF29627_RS10600	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CDIF29627_RS10615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS10620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CDIF29627_RS10625	COG1923	regulation of RNA biosynthetic process
CDIF29627_RS10630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDIF29627_RS10635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDIF29627_RS10640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDIF29627_RS10645	COG1116	anion transmembrane transporter activity
CDIF29627_RS10650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDIF29627_RS10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29627_RS10670	COG1733	regulation of RNA biosynthetic process
CDIF29627_RS10675	COG0384	phenazine biosynthesis protein PhzF
CDIF29627_RS10680	COG0494	nUDIX hydrolase
CDIF29627_RS10690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29627_RS10695	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS10695	COG2247	cell wall binding repeat
CDIF29627_RS10760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDIF29627_RS10785	COG0730	response to heat
CDIF29627_RS10790	COG2207	Transcriptional regulator
CDIF29627_RS10795	COG0789	Transcriptional regulator
CDIF29627_RS10810	COG1404	Belongs to the peptidase S8 family
CDIF29627_RS10830	COG0129	dihydroxy-acid dehydratase activity
CDIF29627_RS10860	COG2207	Transcriptional regulator
CDIF29627_RS10865	COG2814	Major facilitator Superfamily
CDIF29627_RS10885	COG1725	Transcriptional regulator
CDIF29627_RS10910	COG1794	racemase activity, acting on amino acids and derivatives
CDIF29627_RS10920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDIF29627_RS10925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDIF29627_RS10930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDIF29627_RS10935	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDIF29627_RS10945	COG0456	acetyltransferase
CDIF29627_RS10955	COG1309	transcriptional regulator
CDIF29627_RS10975	COG3655	Transcriptional regulator
CDIF29627_RS10990	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS10995	COG1737	Transcriptional regulator
CDIF29627_RS11000	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CDIF29627_RS11005	COG1187	pseudouridine synthase activity
CDIF29627_RS11010	COG0628	permease
CDIF29627_RS11020	COG0019	diaminopimelate decarboxylase activity
CDIF29627_RS11025	COG0527	aspartate kinase activity
CDIF29627_RS11055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDIF29627_RS11060	COG1597	lipid kinase activity
CDIF29627_RS11090	COG0582	viral genome integration into host DNA
CDIF29627_RS11100	COG0488	(ABC) transporter
CDIF29627_RS11115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDIF29627_RS11125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29627_RS11125	COG2080	2 iron, 2 sulfur cluster binding
CDIF29627_RS11135	COG2233	PERMEase
CDIF29627_RS11150	COG0167	dihydroorotate dehydrogenase activity
CDIF29627_RS11155	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29627_RS11175	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29627_RS11200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29627_RS11225	COG3829	transcription factor binding
CDIF29627_RS11235	COG1401	restriction endodeoxyribonuclease activity
CDIF29627_RS11250	COG4708	membrane
CDIF29627_RS11260	COG2080	2 iron, 2 sulfur cluster binding
CDIF29627_RS11260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29627_RS11295	COG1131	(ABC) transporter
CDIF29627_RS11305	COG2252	PERMEase
CDIF29627_RS11310	COG0534	Mate efflux family protein
CDIF29627_RS11320	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDIF29627_RS11325	COG1349	DNA-binding transcription factor activity
CDIF29627_RS11335	COG5002	protein histidine kinase activity
CDIF29627_RS11340	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS11345	COG2217	Heavy metal translocating P-type atpase
CDIF29627_RS11360	COG1217	gtp-binding protein TYPA
CDIF29627_RS11365	COG0492	ferredoxin-NADP+ reductase activity
CDIF29627_RS11405	COG1247	-acetyltransferase
CDIF29627_RS11430	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDIF29627_RS11435	COG0750	zinc metalloprotease
CDIF29627_RS11440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDIF29627_RS11465	COG4589	Belongs to the CDS family
CDIF29627_RS11480	COG0233	cytoplasmic translational termination
CDIF29627_RS11485	COG0528	UMP kinase activity
CDIF29627_RS11490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDIF29627_RS11495	COG0052	Belongs to the universal ribosomal protein uS2 family
CDIF29627_RS11500	COG1686	Belongs to the peptidase S11 family
CDIF29627_RS11515	COG1971	Probably functions as a manganese efflux pump
CDIF29627_RS11520	COG1193	negative regulation of DNA recombination
CDIF29627_RS11535	COG2720	vancomycin resistance protein
CDIF29627_RS11555	COG1363	Peptidase, m42
CDIF29627_RS11565	COG1160	GTP binding
CDIF29627_RS11570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDIF29627_RS11620	COG0039	L-malate dehydrogenase activity
CDIF29627_RS11630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDIF29627_RS11630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDIF29627_RS11640	COG1151	hydroxylamine reductase activity
CDIF29627_RS11660	COG0437	4 iron, 4 sulfur cluster binding
CDIF29627_RS11670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDIF29627_RS11675	COG2945	thiolester hydrolase activity
CDIF29627_RS11675	COG0596	Alpha beta hydrolase
CDIF29627_RS11705	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDIF29627_RS11710	COG1554	hydrolase, family 65, central catalytic
CDIF29627_RS11715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29627_RS11725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29627_RS11735	COG2385	sporulation resulting in formation of a cellular spore
CDIF29627_RS11735	COG2247	cell wall binding repeat
CDIF29627_RS11745	COG1528	Iron-storage protein
CDIF29627_RS11765	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDIF29627_RS11765	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDIF29627_RS11775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29627_RS11790	COG1309	transcriptional regulator
CDIF29627_RS11800	COG0628	permease
CDIF29627_RS11805	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29627_RS11820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDIF29627_RS11845	COG0288	reversible hydration of carbon dioxide
CDIF29627_RS11865	COG0710	3-dehydroquinate dehydratase activity
CDIF29627_RS11880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29627_RS11940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDIF29627_RS11945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29627_RS11950	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CDIF29627_RS11965	COG5001	Diguanylate cyclase
CDIF29627_RS11965	COG3706	GGDEF domain
CDIF29627_RS11965	COG2203	Gaf domain
CDIF29627_RS11965	COG4251	negative regulation of phosphorylation
CDIF29627_RS11970	COG0017	Asparaginyl-tRNA synthetase
CDIF29627_RS11980	COG1404	Belongs to the peptidase S8 family
CDIF29627_RS11985	COG1404	Belongs to the peptidase S8 family
CDIF29627_RS11995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDIF29627_RS12010	COG1509	lysine 2,3-aminomutase activity
CDIF29627_RS12015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS12020	COG1794	racemase activity, acting on amino acids and derivatives
CDIF29627_RS12040	COG0662	Cupin 2, conserved barrel domain protein
CDIF29627_RS12045	COG3104	oligopeptide transport
CDIF29627_RS12050	COG0006	proline dipeptidase activity
CDIF29627_RS12055	COG3104	oligopeptide transport
CDIF29627_RS12060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDIF29627_RS12075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDIF29627_RS12075	COG0723	plastoquinol--plastocyanin reductase activity
CDIF29627_RS12080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS12080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS12080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS12085	COG1105	Belongs to the carbohydrate kinase PfkB family
CDIF29627_RS12090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS12090	COG3711	transcriptional antiterminator
CDIF29627_RS12095	COG2365	Tyrosine phosphatase family
CDIF29627_RS12115	COG1115	amino acid carrier protein
CDIF29627_RS12120	COG0235	Class ii aldolase
CDIF29627_RS12125	COG0235	Class ii aldolase
CDIF29627_RS12130	COG1063	alcohol dehydrogenase
CDIF29627_RS12135	COG3775	system Galactitol-specific IIC component
CDIF29627_RS12140	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29627_RS12145	COG2213	PTS system mannitol-specific
CDIF29627_RS12145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS12150	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS12150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS12160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS12165	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDIF29627_RS12175	COG5002	protein histidine kinase activity
CDIF29627_RS12220	COG2267	carboxylic ester hydrolase activity
CDIF29627_RS12265	COG3299	homolog of phage Mu protein gp47
CDIF29627_RS12285	COG0582	viral genome integration into host DNA
CDIF29627_RS12310	COG3620	sequence-specific DNA binding
CDIF29627_RS12335	COG3842	ATPase activity
CDIF29627_RS12355	COG2205	protein histidine kinase activity
CDIF29627_RS12360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29627_RS12365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDIF29627_RS12370	COG0698	ribose 5-phosphate isomerase
CDIF29627_RS12375	COG3958	Transketolase
CDIF29627_RS12380	COG3959	Transketolase, thiamine diphosphate binding domain
CDIF29627_RS12395	COG3775	system Galactitol-specific IIC component
CDIF29627_RS12400	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29627_RS12410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29627_RS12410	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29627_RS12415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDIF29627_RS12420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDIF29627_RS12425	COG0246	Mannitol dehydrogenase
CDIF29627_RS12435	COG3711	transcriptional antiterminator
CDIF29627_RS12445	COG0516	GMP reductase activity
CDIF29627_RS12445	COG0517	IMP dehydrogenase activity
CDIF29627_RS12450	COG3853	Toxic anion resistance protein (TelA)
CDIF29627_RS12460	COG1454	alcohol dehydrogenase
CDIF29627_RS12465	COG0427	acetyl-CoA hydrolase
CDIF29627_RS12480	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29627_RS12485	COG0427	acetyl-CoA hydrolase
CDIF29627_RS12490	COG2985	domain, Protein
CDIF29627_RS12490	COG0490	domain, Protein
CDIF29627_RS12490	COG0490	domain, Protein
CDIF29627_RS12490	COG2985	domain, Protein
CDIF29627_RS12495	COG0583	DNA-binding transcription factor activity
CDIF29627_RS12505	COG0006	proline dipeptidase activity
CDIF29627_RS12535	COG3118	belongs to the thioredoxin family
CDIF29627_RS12570	COG1116	anion transmembrane transporter activity
CDIF29627_RS12580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29627_RS12620	COG0157	Belongs to the NadC ModD family
CDIF29627_RS12630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDIF29627_RS12635	COG1966	Carbon starvation protein
CDIF29627_RS12650	COG0628	permease
CDIF29627_RS12660	COG2364	Membrane
CDIF29627_RS12665	COG3426	butyrate kinase activity
CDIF29627_RS12690	COG2199	diguanylate cyclase activity
CDIF29627_RS12695	COG2203	Gaf domain
CDIF29627_RS12695	COG2199	diguanylate cyclase activity
CDIF29627_RS12735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29627_RS12735	COG0072	phenylalanine-tRNA ligase activity
CDIF29627_RS12740	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDIF29627_RS12745	COG2176	DNA-directed DNA polymerase activity
CDIF29627_RS12765	COG0037	tRNA processing
CDIF29627_RS12780	COG3546	catalase activity
CDIF29627_RS12785	COG0791	NLP P60 protein
CDIF29627_RS12785	COG1388	LysM domain
CDIF29627_RS12785	COG3103	Sh3 type 3 domain protein
CDIF29627_RS12795	COG0551	DNA topoisomerase type I activity
CDIF29627_RS12795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDIF29627_RS12825	COG0574	Belongs to the PEP-utilizing enzyme family
CDIF29627_RS12825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDIF29627_RS12830	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDIF29627_RS12835	COG0517	IMP dehydrogenase activity
CDIF29627_RS12855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS12855	COG3711	transcriptional antiterminator
CDIF29627_RS12860	COG3732	PTS system glucitol sorbitol-specific
CDIF29627_RS12870	COG2207	Transcriptional regulator
CDIF29627_RS12885	COG1115	amino acid carrier protein
CDIF29627_RS12890	COG2223	nitrite transmembrane transporter activity
CDIF29627_RS12895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS12900	COG0280	phosphate acetyltransferase
CDIF29627_RS12920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDIF29627_RS12920	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDIF29627_RS12930	COG1414	Transcriptional regulator
CDIF29627_RS12940	COG0751	glycine-tRNA ligase activity
CDIF29627_RS12945	COG0752	glycyl-tRNA synthetase alpha subunit
CDIF29627_RS12955	COG1381	Involved in DNA repair and RecF pathway recombination
CDIF29627_RS12965	COG2239	Acts as a magnesium transporter
CDIF29627_RS12970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDIF29627_RS12975	COG0295	cytidine deaminase activity
CDIF29627_RS12980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDIF29627_RS12985	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDIF29627_RS12990	COG1702	phosphate starvation-inducible protein PhoH
CDIF29627_RS13010	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CDIF29627_RS13015	COG1610	YqeY-like protein
CDIF29627_RS13020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDIF29627_RS13025	COG0537	adenosine 5'-monophosphoramidase activity
CDIF29627_RS13030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29627_RS13035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDIF29627_RS13040	COG2264	protein methyltransferase activity
CDIF29627_RS13080	COG3842	ATPase activity
CDIF29627_RS13085	COG2508	Transcriptional regulator
CDIF29627_RS13090	COG0477	Major facilitator Superfamily
CDIF29627_RS13105	COG0484	heat shock protein binding
CDIF29627_RS13110	COG0443	Heat shock 70 kDa protein
CDIF29627_RS13115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDIF29627_RS13120	COG1420	regulation of RNA biosynthetic process
CDIF29627_RS13125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDIF29627_RS13130	COG0531	amino acid
CDIF29627_RS13135	COG0617	tRNA 3'-terminal CCA addition
CDIF29627_RS13140	COG0481	GTPase activity
CDIF29627_RS13175	COG0268	Binds directly to 16S ribosomal RNA
CDIF29627_RS13185	COG2333	competence protein COMEC
CDIF29627_RS13185	COG0658	competence protein
CDIF29627_RS13205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDIF29627_RS13210	COG1388	LysM domain
CDIF29627_RS13210	COG3584	3D domain protein
CDIF29627_RS13215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDIF29627_RS13230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29627_RS13235	COG0006	proline dipeptidase activity
CDIF29627_RS13240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS13245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS13255	COG3711	transcriptional antiterminator
CDIF29627_RS13255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS13260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS13265	COG1482	cell wall glycoprotein biosynthetic process
CDIF29627_RS13270	COG5002	protein histidine kinase activity
CDIF29627_RS13290	COG1555	photosystem II stabilization
CDIF29627_RS13295	COG1686	Belongs to the peptidase S11 family
CDIF29627_RS13305	COG0165	Argininosuccinate lyase
CDIF29627_RS13310	COG0561	phosphatase activity
CDIF29627_RS13315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29627_RS13320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDIF29627_RS13325	COG1876	peptidase activity
CDIF29627_RS13330	COG1309	transcriptional regulator
CDIF29627_RS13335	COG2814	Major facilitator Superfamily
CDIF29627_RS13345	COG4977	sequence-specific DNA binding
CDIF29627_RS13355	COG1263	PTS System
CDIF29627_RS13355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS13360	COG3711	transcriptional antiterminator
CDIF29627_RS13365	COG2190	(PTS) system
CDIF29627_RS13365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS13365	COG1263	PTS System
CDIF29627_RS13370	COG0251	oxidation-reduction process
CDIF29627_RS13375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDIF29627_RS13470	COG0495	leucyl-tRNA aminoacylation
CDIF29627_RS13475	COG0799	negative regulation of ribosome biogenesis
CDIF29627_RS13480	COG1713	HD superfamily hydrolase involved in NAD metabolism
CDIF29627_RS13485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDIF29627_RS13490	COG2137	regulation of response to DNA damage stimulus
CDIF29627_RS13495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDIF29627_RS13500	COG1309	transcriptional regulator
CDIF29627_RS13525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDIF29627_RS13535	COG0577	efflux transmembrane transporter activity
CDIF29627_RS13535	COG1136	(ABC) transporter
CDIF29627_RS13545	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS13550	COG0737	Belongs to the 5'-nucleotidase family
CDIF29627_RS13560	COG1234	tRNA 3'-trailer cleavage
CDIF29627_RS13565	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDIF29627_RS13570	COG1823	symporter activity
CDIF29627_RS13595	COG4124	Belongs to the glycosyl hydrolase 26 family
CDIF29627_RS13595	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDIF29627_RS13605	COG0395	ABC-type sugar transport system, permease component
CDIF29627_RS13625	COG4821	SIS domain
CDIF29627_RS13655	COG0742	ribosomal rna small subunit methyltransferase
CDIF29627_RS13660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDIF29627_RS13665	COG1461	Dihydroxyacetone kinase
CDIF29627_RS13670	COG1302	Protein conserved in bacteria
CDIF29627_RS13675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDIF29627_RS13690	COG0789	Transcriptional regulator
CDIF29627_RS13695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS13695	COG3711	transcriptional antiterminator
CDIF29627_RS13700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS13700	COG3711	transcriptional antiterminator
CDIF29627_RS13705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS13705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS13705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS13710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS13715	COG0383	alpha-mannosidase activity
CDIF29627_RS13740	COG1564	THIamine pyrophosphokinase
CDIF29627_RS13745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDIF29627_RS13750	COG1162	GTPase activity
CDIF29627_RS13755	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29627_RS13760	COG0515	serine threonine protein kinase
CDIF29627_RS13760	COG2815	serine threonine protein kinase
CDIF29627_RS13770	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDIF29627_RS13775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDIF29627_RS13775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDIF29627_RS13780	COG2738	Putative neutral zinc metallopeptidase
CDIF29627_RS13790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDIF29627_RS13795	COG0242	peptide deformylase activity
CDIF29627_RS13800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDIF29627_RS13805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDIF29627_RS13810	COG1758	RNA polymerase activity
CDIF29627_RS13815	COG0194	GDP metabolic process
CDIF29627_RS13820	COG1561	YicC-like family, N-terminal region
CDIF29627_RS13825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDIF29627_RS13835	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CDIF29627_RS13840	COG0488	(ABC) transporter
CDIF29627_RS13850	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDIF29627_RS13855	COG0564	pseudouridine synthase activity
CDIF29627_RS13860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDIF29627_RS13870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDIF29627_RS13880	COG2801	Transposase and inactivated derivatives
CDIF29627_RS13885	COG1966	Carbon starvation protein
CDIF29627_RS13890	COG3279	Response regulator of the LytR AlgR family
CDIF29627_RS13895	COG3275	phosphorelay sensor kinase activity
CDIF29627_RS13900	COG0180	Tryptophanyl-tRNA synthetase
CDIF29627_RS13905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDIF29627_RS13910	COG0531	amino acid
CDIF29627_RS13915	COG0006	proline dipeptidase activity
CDIF29627_RS13920	COG1307	EDD domain protein, DegV family
CDIF29627_RS13935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29627_RS13940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDIF29627_RS13960	COG1799	cell septum assembly
CDIF29627_RS13965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDIF29627_RS13985	COG3830	Belongs to the UPF0237 family
CDIF29627_RS13995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDIF29627_RS14000	COG2271	Major facilitator Superfamily
CDIF29627_RS14005	COG0531	amino acid
CDIF29627_RS14010	COG0006	proline dipeptidase activity
CDIF29627_RS14020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDIF29627_RS14025	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDIF29627_RS14030	COG1160	GTP binding
CDIF29627_RS14055	COG5002	protein histidine kinase activity
CDIF29627_RS14060	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS14070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDIF29627_RS14075	COG1873	PFAM PRC-barrel domain
CDIF29627_RS14080	COG1191	sigma factor activity
CDIF29627_RS14085	COG1191	sigma factor activity
CDIF29627_RS14100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDIF29627_RS14105	COG3856	small basic protein
CDIF29627_RS14125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29627_RS14130	COG0772	Belongs to the SEDS family
CDIF29627_RS14135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDIF29627_RS14140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDIF29627_RS14145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDIF29627_RS14150	COG0768	penicillin binding
CDIF29627_RS14160	COG0275	rRNA processing
CDIF29627_RS14165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDIF29627_RS14170	COG0612	Peptidase, M16
CDIF29627_RS14180	COG0012	GTP binding
CDIF29627_RS14195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDIF29627_RS14205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS14205	COG1263	PTS System
CDIF29627_RS14205	COG2190	(PTS) system
CDIF29627_RS14210	COG3711	transcriptional antiterminator
CDIF29627_RS14215	COG0025	NhaP-type Na H and K H
CDIF29627_RS14220	COG4608	Belongs to the ABC transporter superfamily
CDIF29627_RS14225	COG0444	Belongs to the ABC transporter superfamily
CDIF29627_RS14235	COG0601	transmembrane transport
CDIF29627_RS14240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDIF29627_RS14245	COG0583	DNA-binding transcription factor activity
CDIF29627_RS14250	COG0183	Belongs to the thiolase family
CDIF29627_RS14255	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDIF29627_RS14265	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29627_RS14270	COG2610	gluconate transmembrane transporter activity
CDIF29627_RS14275	COG2340	Cysteine-rich secretory protein family
CDIF29627_RS14290	COG4869	propanediol catabolic process
CDIF29627_RS14325	COG2081	HI0933 family
CDIF29627_RS14330	COG0671	phosphoesterase, PA-phosphatase related
CDIF29627_RS14340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29627_RS14355	COG2502	aspartate--ammonia ligase
CDIF29627_RS14360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29627_RS14365	COG1473	amidohydrolase
CDIF29627_RS14375	COG3366	ferrous iron transmembrane transporter activity
CDIF29627_RS14400	COG2252	PERMEase
CDIF29627_RS14405	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29627_RS14415	COG2271	Major facilitator Superfamily
CDIF29627_RS14435	COG0583	DNA-binding transcription factor activity
CDIF29627_RS14445	COG1376	ErfK ybiS ycfS ynhG family protein
CDIF29627_RS14450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDIF29627_RS14455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDIF29627_RS14480	COG4509	Sortase family
CDIF29627_RS14505	COG3069	C4-dicarboxylate transmembrane transporter activity
CDIF29627_RS14510	COG0642	Histidine kinase
CDIF29627_RS14510	COG5002	protein histidine kinase activity
CDIF29627_RS14515	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS14530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29627_RS14535	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDIF29627_RS14555	COG1937	Protein conserved in bacteria
CDIF29627_RS14570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29627_RS14575	COG1757	Na H antiporter
CDIF29627_RS14585	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14585	COG2247	cell wall binding repeat
CDIF29627_RS14590	COG0583	DNA-binding transcription factor activity
CDIF29627_RS14595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDIF29627_RS14605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDIF29627_RS14610	COG0124	histidyl-tRNA synthetase
CDIF29627_RS14615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDIF29627_RS14625	COG1490	D-aminoacyl-tRNA deacylase activity
CDIF29627_RS14630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDIF29627_RS14635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDIF29627_RS14640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDIF29627_RS14640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDIF29627_RS14685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS14710	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDIF29627_RS14725	COG0561	phosphatase activity
CDIF29627_RS14730	COG1316	TRANSCRIPTIONal
CDIF29627_RS14735	COG1316	TRANSCRIPTIONal
CDIF29627_RS14740	COG1649	PFAM Uncharacterised BCR, COG1649
CDIF29627_RS14745	COG0791	NLP P60 protein
CDIF29627_RS14755	COG0438	transferase activity, transferring glycosyl groups
CDIF29627_RS14760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDIF29627_RS14765	COG1215	transferase activity, transferring glycosyl groups
CDIF29627_RS14775	COG1215	transferase activity, transferring glycosyl groups
CDIF29627_RS14780	COG1215	transferase activity, transferring glycosyl groups
CDIF29627_RS14780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDIF29627_RS14785	COG1216	Glycosyl transferase, family 2
CDIF29627_RS14805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29627_RS14810	COG0728	peptidoglycan biosynthetic process
CDIF29627_RS14815	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14815	COG2247	cell wall binding repeat
CDIF29627_RS14820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDIF29627_RS14825	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14835	COG2247	cell wall binding repeat
CDIF29627_RS14835	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14845	COG2246	polysaccharide biosynthetic process
CDIF29627_RS14850	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14850	COG2247	cell wall binding repeat
CDIF29627_RS14865	COG0653	protein targeting
CDIF29627_RS14900	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS14900	COG2247	cell wall binding repeat
CDIF29627_RS14920	COG0343	queuine tRNA-ribosyltransferase activity
CDIF29627_RS14930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDIF29627_RS14935	COG2255	four-way junction helicase activity
CDIF29627_RS14940	COG0632	four-way junction helicase activity
CDIF29627_RS14945	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDIF29627_RS14970	COG2610	gluconate transmembrane transporter activity
CDIF29627_RS14975	COG2084	Dehydrogenase
CDIF29627_RS14995	COG1132	(ABC) transporter
CDIF29627_RS15015	COG0700	Nucleoside recognition
CDIF29627_RS15020	COG3366	ferrous iron transmembrane transporter activity
CDIF29627_RS15025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS15055	COG0436	Aminotransferase
CDIF29627_RS15060	COG0697	spore germination
CDIF29627_RS15075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDIF29627_RS15080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS15085	COG0076	glutamate decarboxylase activity
CDIF29627_RS15095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDIF29627_RS15100	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDIF29627_RS15105	COG1473	amidohydrolase
CDIF29627_RS15110	COG3949	Membrane
CDIF29627_RS15125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDIF29627_RS15140	COG0604	alcohol dehydrogenase
CDIF29627_RS15150	COG1592	Rubrerythrin
CDIF29627_RS15155	COG0789	Transcriptional regulator
CDIF29627_RS15165	COG1664	Polymer-forming cytoskeletal
CDIF29627_RS15170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDIF29627_RS15170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29627_RS15175	COG1349	DNA-binding transcription factor activity
CDIF29627_RS15180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDIF29627_RS15185	COG1696	Membrane protein involved in D-alanine export
CDIF29627_RS15190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDIF29627_RS15200	COG0673	inositol 2-dehydrogenase activity
CDIF29627_RS15210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29627_RS15215	COG1253	flavin adenine dinucleotide binding
CDIF29627_RS15220	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDIF29627_RS15240	COG3829	transcription factor binding
CDIF29627_RS15240	COG3290	protein histidine kinase activity
CDIF29627_RS15245	COG2267	carboxylic ester hydrolase activity
CDIF29627_RS15255	COG0312	modulator of DNA gyrase
CDIF29627_RS15260	COG0312	modulator of DNA gyrase
CDIF29627_RS15285	COG2721	sulfolactate sulfo-lyase activity
CDIF29627_RS15290	COG3706	GGDEF domain
CDIF29627_RS15290	COG5001	Diguanylate cyclase
CDIF29627_RS15290	COG2203	Gaf domain
CDIF29627_RS15290	COG4251	negative regulation of phosphorylation
CDIF29627_RS15300	COG1120	ATPase activity
CDIF29627_RS15305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29627_RS15310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29627_RS15325	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29627_RS15330	COG3394	polysaccharide catabolic process
CDIF29627_RS15335	COG1486	melibiose metabolic process
CDIF29627_RS15340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS15350	COG2188	Transcriptional regulator
CDIF29627_RS15355	COG0534	Mate efflux family protein
CDIF29627_RS15360	COG2199	diguanylate cyclase activity
CDIF29627_RS15370	COG3842	ATPase activity
CDIF29627_RS15375	COG1840	ABC-type Fe3 transport system, periplasmic component
CDIF29627_RS15380	COG1394	ATPase activity, coupled to movement of substances
CDIF29627_RS15385	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CDIF29627_RS15390	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CDIF29627_RS15405	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CDIF29627_RS15410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDIF29627_RS15415	COG1269	ATP hydrolysis coupled proton transport
CDIF29627_RS15440	COG5001	Diguanylate cyclase
CDIF29627_RS15440	COG3300	MHYT domain
CDIF29627_RS15445	COG1454	alcohol dehydrogenase
CDIF29627_RS15445	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29627_RS15455	COG2801	Transposase and inactivated derivatives
CDIF29627_RS15465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDIF29627_RS15475	COG0318	PFAM AMP-dependent synthetase and ligase
CDIF29627_RS15480	COG0183	Belongs to the thiolase family
CDIF29627_RS15520	COG0577	efflux transmembrane transporter activity
CDIF29627_RS15525	COG1136	(ABC) transporter
CDIF29627_RS15530	COG1968	undecaprenyl-diphosphatase activity
CDIF29627_RS15535	COG2205	protein histidine kinase activity
CDIF29627_RS15540	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS15555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29627_RS15570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDIF29627_RS15575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDIF29627_RS15585	COG1120	ATPase activity
CDIF29627_RS15590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29627_RS15600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29627_RS15605	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDIF29627_RS15610	COG2721	sulfolactate sulfo-lyase activity
CDIF29627_RS15630	COG1454	alcohol dehydrogenase
CDIF29627_RS15635	COG1376	ErfK ybiS ycfS ynhG family protein
CDIF29627_RS15650	COG2801	Transposase and inactivated derivatives
CDIF29627_RS15655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDIF29627_RS15660	COG0785	Cytochrome C biogenesis protein
CDIF29627_RS15665	COG1733	regulation of RNA biosynthetic process
CDIF29627_RS15685	COG0383	alpha-mannosidase activity
CDIF29627_RS15690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS15695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS15700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS15700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS15700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS15705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS15705	COG3711	transcriptional antiterminator
CDIF29627_RS15710	COG4975	Glucose uptake
CDIF29627_RS15740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDIF29627_RS15755	COG0517	IMP dehydrogenase activity
CDIF29627_RS15755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDIF29627_RS15760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29627_RS15765	COG1263	PTS System
CDIF29627_RS15765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS15770	COG3711	transcriptional antiterminator
CDIF29627_RS15775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDIF29627_RS15780	COG3118	belongs to the thioredoxin family
CDIF29627_RS15790	COG0384	phenazine biosynthesis protein PhzF
CDIF29627_RS15810	COG0542	response to heat
CDIF29627_RS15820	COG2267	carboxylic ester hydrolase activity
CDIF29627_RS15835	COG1737	Transcriptional regulator
CDIF29627_RS15855	COG2971	BadF BadG BcrA BcrD
CDIF29627_RS15860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDIF29627_RS15870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS15885	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDIF29627_RS15890	COG0642	Histidine kinase
CDIF29627_RS15905	COG1136	(ABC) transporter
CDIF29627_RS15915	COG2190	(PTS) system
CDIF29627_RS15930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS15930	COG1263	PTS System
CDIF29627_RS15945	COG2115	Belongs to the xylose isomerase family
CDIF29627_RS15950	COG1070	Carbohydrate kinase
CDIF29627_RS15965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS15965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS15970	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29627_RS16000	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDIF29627_RS16025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDIF29627_RS16030	COG0191	fructose-bisphosphate aldolase activity
CDIF29627_RS16035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS16050	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS16060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS16070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS16070	COG2213	PTS system mannitol-specific
CDIF29627_RS16075	COG1929	Belongs to the glycerate kinase type-1 family
CDIF29627_RS16080	COG0383	alpha-mannosidase activity
CDIF29627_RS16085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS16085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16095	COG3394	polysaccharide catabolic process
CDIF29627_RS16100	COG2190	(PTS) system
CDIF29627_RS16100	COG1263	PTS System
CDIF29627_RS16100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16105	COG2188	Transcriptional regulator
CDIF29627_RS16110	COG0366	Alpha amylase catalytic
CDIF29627_RS16120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDIF29627_RS16135	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS16140	COG1263	PTS System
CDIF29627_RS16140	COG2190	(PTS) system
CDIF29627_RS16140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16145	COG3711	transcriptional antiterminator
CDIF29627_RS16155	COG1288	antiporter activity
CDIF29627_RS16160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16160	COG1263	PTS System
CDIF29627_RS16165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29627_RS16175	COG0561	phosphatase activity
CDIF29627_RS16180	COG1454	alcohol dehydrogenase
CDIF29627_RS16185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDIF29627_RS16190	COG3711	transcriptional antiterminator
CDIF29627_RS16190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS16195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29627_RS16200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDIF29627_RS16205	COG0205	6-phosphofructokinase activity
CDIF29627_RS16215	COG1473	amidohydrolase
CDIF29627_RS16220	COG1473	amidohydrolase
CDIF29627_RS16230	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS16235	COG2190	(PTS) system
CDIF29627_RS16235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16235	COG1263	PTS System
CDIF29627_RS16250	COG1819	glycosyl
CDIF29627_RS16255	COG3620	sequence-specific DNA binding
CDIF29627_RS16265	COG2223	nitrite transmembrane transporter activity
CDIF29627_RS16270	COG1695	Transcriptional regulator
CDIF29627_RS16280	COG0640	Transcriptional regulator
CDIF29627_RS16290	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS16295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16295	COG2190	(PTS) system
CDIF29627_RS16295	COG1263	PTS System
CDIF29627_RS16300	COG3711	transcriptional antiterminator
CDIF29627_RS16305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16305	COG1263	PTS System
CDIF29627_RS16310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29627_RS16320	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS16330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS16335	COG3711	transcriptional antiterminator
CDIF29627_RS16340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS16340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29627_RS16345	COG0191	fructose-bisphosphate aldolase activity
CDIF29627_RS16350	COG2723	6-phospho-beta-galactosidase activity
CDIF29627_RS16355	COG2190	(PTS) system
CDIF29627_RS16355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS16355	COG1263	PTS System
CDIF29627_RS16360	COG3711	transcriptional antiterminator
CDIF29627_RS16385	COG0693	protein deglycase activity
CDIF29627_RS16400	COG4509	Sortase family
CDIF29627_RS16410	COG1136	(ABC) transporter
CDIF29627_RS16540	COG2003	Belongs to the UPF0758 family
CDIF29627_RS16575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDIF29627_RS16585	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS16585	COG1388	LysM domain
CDIF29627_RS16630	COG3299	homolog of phage Mu protein gp47
CDIF29627_RS16645	COG0791	NLP P60 protein
CDIF29627_RS16650	COG1652	LysM domain
CDIF29627_RS16700	COG0740	serine-type endopeptidase activity
CDIF29627_RS16760	COG0305	Participates in initiation and elongation during chromosome replication
CDIF29627_RS16785	COG1396	sequence-specific DNA binding
CDIF29627_RS16800	COG0582	viral genome integration into host DNA
CDIF29627_RS16810	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDIF29627_RS16835	COG1131	(ABC) transporter
CDIF29627_RS16845	COG0557	exoribonuclease II activity
CDIF29627_RS16860	COG1881	PFAM PEBP family protein
CDIF29627_RS16890	COG0148	phosphopyruvate hydratase activity
CDIF29627_RS16895	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDIF29627_RS16900	COG0149	triose-phosphate isomerase activity
CDIF29627_RS16905	COG0126	phosphoglycerate kinase activity
CDIF29627_RS16915	COG2390	Transcriptional regulator
CDIF29627_RS16920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDIF29627_RS16925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29627_RS16935	COG0167	dihydroorotate dehydrogenase activity
CDIF29627_RS16945	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29627_RS16950	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDIF29627_RS16970	COG3829	transcription factor binding
CDIF29627_RS16975	COG0251	oxidation-reduction process
CDIF29627_RS16990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDIF29627_RS16995	COG0789	Transcriptional regulator
CDIF29627_RS17005	COG2247	cell wall binding repeat
CDIF29627_RS17005	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29627_RS17010	COG1136	(ABC) transporter
CDIF29627_RS17015	COG0577	efflux transmembrane transporter activity
CDIF29627_RS17020	COG4585	Histidine kinase
CDIF29627_RS17035	COG2207	Transcriptional regulator
CDIF29627_RS17040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29627_RS17050	COG0789	Transcriptional regulator
CDIF29627_RS17075	COG2770	Histidine kinase
CDIF29627_RS17075	COG2205	protein histidine kinase activity
CDIF29627_RS17080	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS17085	COG0706	membrane insertase activity
CDIF29627_RS17095	COG0778	Nitroreductase
CDIF29627_RS17105	COG0534	Mate efflux family protein
CDIF29627_RS17135	COG2207	Transcriptional regulator
CDIF29627_RS17145	COG1732	Glycine betaine
CDIF29627_RS17150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29627_RS17160	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDIF29627_RS17165	COG2226	methyltransferase
CDIF29627_RS17175	COG1473	amidohydrolase
CDIF29627_RS17180	COG1760	l-serine dehydratase
CDIF29627_RS17190	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDIF29627_RS17195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29627_RS17200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDIF29627_RS17205	COG2171	N-acyltransferase activity
CDIF29627_RS17215	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDIF29627_RS17250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDIF29627_RS17270	COG3843	relaxase mobilization nuclease domain protein
CDIF29627_RS17280	COG0515	serine threonine protein kinase
CDIF29627_RS17280	COG3064	Membrane
CDIF29627_RS17280	COG4991	sh3 domain protein
CDIF29627_RS17305	COG0551	DNA topoisomerase type I activity
CDIF29627_RS17305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDIF29627_RS17320	COG0791	NLP P60 protein
CDIF29627_RS17320	COG0741	lytic transglycosylase activity
CDIF29627_RS17375	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDIF29627_RS17380	COG3681	Belongs to the UPF0597 family
CDIF29627_RS17390	COG3829	transcription factor binding
CDIF29627_RS17395	COG2226	methyltransferase
CDIF29627_RS17420	COG0252	asparaginase activity
CDIF29627_RS17420	COG5275	peptidyl-tyrosine sulfation
CDIF29627_RS17425	COG5275	peptidyl-tyrosine sulfation
CDIF29627_RS17425	COG0252	asparaginase activity
CDIF29627_RS17440	COG0252	asparaginase activity
CDIF29627_RS17440	COG5275	peptidyl-tyrosine sulfation
CDIF29627_RS17460	COG4656	Part of a membrane complex involved in electron transport
CDIF29627_RS17470	COG0726	polysaccharide deacetylase
CDIF29627_RS17495	COG0285	dihydrofolate synthase activity
CDIF29627_RS17505	COG3279	Response regulator of the LytR AlgR family
CDIF29627_RS17510	COG0525	valine-tRNA ligase activity
CDIF29627_RS17520	COG0726	polysaccharide deacetylase
CDIF29627_RS17535	COG0704	Plays a role in the regulation of phosphate uptake
CDIF29627_RS17540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDIF29627_RS17545	COG0581	inorganic phosphate transmembrane transporter activity
CDIF29627_RS17550	COG0573	inorganic phosphate transmembrane transporter activity
CDIF29627_RS17560	COG1131	(ABC) transporter
CDIF29627_RS17585	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS17590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDIF29627_RS17595	COG1164	Oligoendopeptidase f
CDIF29627_RS17600	COG1285	pathogenesis
CDIF29627_RS17625	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDIF29627_RS17630	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29627_RS17635	COG3715	PTS system
CDIF29627_RS17640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS17640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS17645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29627_RS17645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29627_RS17655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDIF29627_RS17670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDIF29627_RS17675	COG0166	Belongs to the GPI family
CDIF29627_RS17685	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CDIF29627_RS17700	COG1405	negative regulation of cell septum assembly
CDIF29627_RS17700	COG3012	SEC-C Motif Domain Protein
CDIF29627_RS17725	COG1459	type II secretion system
CDIF29627_RS17730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDIF29627_RS17745	COG2814	Major facilitator Superfamily
CDIF29627_RS17750	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDIF29627_RS17755	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDIF29627_RS17765	COG2059	Chromate
CDIF29627_RS17770	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDIF29627_RS17775	COG0740	serine-type endopeptidase activity
CDIF29627_RS17780	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDIF29627_RS17795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDIF29627_RS17815	COG0493	'glutamate synthase
CDIF29627_RS17815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29627_RS17825	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29627_RS17835	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDIF29627_RS17885	COG0463	Glycosyl transferase, family 2
CDIF29627_RS17885	COG0457	Tetratricopeptide repeat
CDIF29627_RS17900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS17910	COG0778	Nitroreductase
CDIF29627_RS17915	COG1733	regulation of RNA biosynthetic process
CDIF29627_RS17920	COG0693	protein deglycase activity
CDIF29627_RS17925	COG1522	sequence-specific DNA binding
CDIF29627_RS17930	COG0488	(ABC) transporter
CDIF29627_RS17935	COG0745	RESPONSE REGULATOR receiver
CDIF29627_RS17955	COG4555	ABC transporter
CDIF29627_RS17960	COG2199	diguanylate cyclase activity
CDIF29627_RS18010	COG0205	6-phosphofructokinase activity
CDIF29627_RS18020	COG1481	regulation of sporulation
CDIF29627_RS18035	COG1660	Displays ATPase and GTPase activities
CDIF29627_RS18045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDIF29627_RS18050	COG2116	formate transmembrane transporter activity
CDIF29627_RS18055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDIF29627_RS18085	COG0322	excinuclease ABC activity
CDIF29627_RS18095	COG0556	nucleotide-excision repair
CDIF29627_RS18105	COG1653	transport
CDIF29627_RS18115	COG1175	transmembrane transport
CDIF29627_RS18120	COG3842	ATPase activity
CDIF29627_RS18140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDIF29627_RS18140	COG1648	precorrin-2 dehydrogenase activity
CDIF29627_RS18145	COG0113	porphobilinogen synthase activity
CDIF29627_RS18155	COG0181	hydroxymethylbilane synthase activity
CDIF29627_RS18165	COG2099	Precorrin-6x reductase
CDIF29627_RS18195	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CDIF29627_RS18210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29627_RS18220	COG1797	cobyrinic acid a,c-diamide synthase activity
CDIF29627_RS18225	COG1492	cobalamin metabolic process
CDIF29627_RS18235	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDIF29627_RS18240	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CDIF29627_RS18245	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDIF29627_RS18265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29627_RS18280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS18285	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29627_RS18290	COG1363	Peptidase, m42
CDIF29627_RS18295	COG3711	transcriptional antiterminator
CDIF29627_RS18300	COG0191	fructose-bisphosphate aldolase activity
CDIF29627_RS18305	COG2222	sugar isomerase
CDIF29627_RS18310	COG0673	inositol 2-dehydrogenase activity
CDIF29627_RS18320	COG2188	Transcriptional regulator
CDIF29627_RS18345	COG0793	Belongs to the peptidase S41A family
CDIF29627_RS18345	COG3409	Peptidoglycan-binding domain 1 protein
CDIF29627_RS18350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDIF29627_RS18360	COG3949	Membrane
CDIF29627_RS18365	COG3958	Transketolase
CDIF29627_RS18370	COG3959	Transketolase, thiamine diphosphate binding domain
CDIF29627_RS18375	COG2337	Toxic component of a toxin-antitoxin (TA) module
CDIF29627_RS18395	COG0516	GMP reductase activity
CDIF29627_RS18395	COG0517	IMP dehydrogenase activity
CDIF29627_RS18400	COG0736	holo-[acyl-carrier-protein] synthase activity
CDIF29627_RS18405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDIF29627_RS18410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDIF29627_RS18415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDIF29627_RS18420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDIF29627_RS18425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDIF29627_RS18430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDIF29627_RS18435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDIF29627_RS18465	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDIF29627_RS18465	COG3608	succinylglutamate desuccinylase aspartoacylase
CDIF29627_RS18470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDIF29627_RS18475	COG0698	ribose 5-phosphate isomerase
CDIF29627_RS18480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDIF29627_RS18485	COG0009	L-threonylcarbamoyladenylate synthase
CDIF29627_RS18495	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDIF29627_RS18500	COG2890	protein-(glutamine-N5) methyltransferase activity
CDIF29627_RS18505	COG3872	metal-dependent enzyme
CDIF29627_RS18510	COG0254	rRNA binding
CDIF29627_RS18515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDIF29627_RS18520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDIF29627_RS18530	COG2208	phosphoserine phosphatase activity
CDIF29627_RS18535	COG0248	Ppx GppA phosphatase
CDIF29627_RS18555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDIF29627_RS18565	COG3956	TIGRFAM MazG family protein
CDIF29627_RS18570	COG2244	polysaccharide biosynthetic process
CDIF29627_RS18575	COG2002	toxin-antitoxin pair type II binding
CDIF29627_RS18580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDIF29627_RS18585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDIF29627_RS18590	COG0193	aminoacyl-tRNA hydrolase activity
CDIF29627_RS18640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDIF29627_RS18655	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDIF29627_RS18660	COG2088	sporulation resulting in formation of a cellular spore
CDIF29627_RS18665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDIF29627_RS18670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDIF29627_RS18680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDIF29627_RS18685	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29627_RS18695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDIF29627_RS18700	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDIF29627_RS18705	COG1840	ABC-type Fe3 transport system, periplasmic component
CDIF29627_RS18710	COG1840	ABC-type Fe3 transport system, periplasmic component
CDIF29627_RS18720	COG3842	ATPase activity
CDIF29627_RS18725	COG0613	PHP domain protein
CDIF29627_RS18730	COG3454	Phosphonate metabolism
CDIF29627_RS18735	COG4778	phosphonate C-P lyase system protein PhnL
CDIF29627_RS18740	COG4107	phosphonate C-P lyase system protein PhnK
CDIF29627_RS18745	COG3627	carbon phosphorus lyase activity
CDIF29627_RS18765	COG0084	hydrolase, TatD family'
CDIF29627_RS18770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29627_RS18770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29627_RS18775	COG0700	Nucleoside recognition
CDIF29627_RS18785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDIF29627_RS18790	COG1522	sequence-specific DNA binding
CDIF29627_RS18795	COG0617	tRNA 3'-terminal CCA addition
CDIF29627_RS18800	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDIF29627_RS18805	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDIF29627_RS18810	COG1774	PSP1 C-terminal conserved region
CDIF29627_RS18815	COG0470	DNA polymerase III
CDIF29627_RS18820	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDIF29627_RS18825	COG1982	Orn Lys Arg decarboxylase major
CDIF29627_RS18830	COG2155	Conserved Protein
CDIF29627_RS18855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDIF29627_RS18860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDIF29627_RS18870	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDIF29627_RS18880	COG3191	aminopeptidase activity
CDIF29627_RS18890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDIF29627_RS18895	COG0037	tRNA processing
CDIF29627_RS18905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDIF29627_RS18920	COG1802	Transcriptional regulator
CDIF29627_RS18925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDIF29627_RS18955	COG0653	protein targeting
CDIF29627_RS18985	COG2271	Major facilitator Superfamily
CDIF29627_RS18990	COG0626	cystathionine gamma-synthase activity
CDIF29627_RS19015	COG0564	pseudouridine synthase activity
CDIF29627_RS19020	COG4978	Transcriptional regulator
CDIF29627_RS19020	COG0789	Transcriptional regulator
CDIF29627_RS19030	COG1136	(ABC) transporter
CDIF29627_RS19030	COG0577	efflux transmembrane transporter activity
CDIF29627_RS19035	COG5002	protein histidine kinase activity
CDIF29627_RS19045	COG1695	Transcriptional regulator
CDIF29627_RS19070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDIF29627_RS19080	COG0284	orotidine-5'-phosphate decarboxylase activity
CDIF29627_RS19100	COG0646	methionine synthase
CDIF29627_RS19100	COG1410	methionine synthase
CDIF29627_RS19110	COG1854	S-ribosylhomocysteine lyase activity
CDIF29627_RS19125	COG1876	peptidase activity
CDIF29627_RS19130	COG0037	tRNA processing
CDIF29627_RS19135	COG1408	metallophosphoesterase
CDIF29627_RS19150	COG1141	Ferredoxin
CDIF29627_RS19155	COG3964	amidohydrolase
CDIF29627_RS19165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDIF29627_RS19175	COG0346	lactoylglutathione lyase activity
CDIF29627_RS19180	COG0534	Mate efflux family protein
CDIF29627_RS19195	COG4978	Transcriptional regulator
CDIF29627_RS19195	COG0789	Transcriptional regulator
CDIF29627_RS19205	COG5504	Zn-dependent protease
CDIF29627_RS19215	COG0519	Catalyzes the synthesis of GMP from XMP
CDIF29627_RS19225	COG1357	PFAM Pentapeptide repeats (8 copies)
CDIF29627_RS19230	COG2824	Alkylphosphonate utilization operon protein PhnA
CDIF29627_RS19245	COG0352	thiamine-phosphate diphosphorylase activity
CDIF29627_RS19250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29627_RS19255	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDIF29627_RS19255	COG0517	IMP dehydrogenase activity
CDIF29627_RS19275	COG1335	isochorismatase
CDIF29627_RS19285	COG0789	Transcriptional regulator
CDIF29627_RS19315	COG0583	DNA-binding transcription factor activity
CDIF29627_RS19320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDIF29627_RS19320	COG1522	sequence-specific DNA binding
CDIF29627_RS19335	COG3964	amidohydrolase
CDIF29627_RS19345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS19350	COG2188	Transcriptional regulator
CDIF29627_RS19355	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29627_RS19360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS19365	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDIF29627_RS19370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29627_RS19375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDIF29627_RS19390	COG1484	DNA-dependent DNA replication
CDIF29627_RS19415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDIF29627_RS19425	COG0305	Participates in initiation and elongation during chromosome replication
CDIF29627_RS19430	COG0359	binds to the 23S rRNA
CDIF29627_RS19435	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CDIF29627_RS19450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDIF29627_RS19455	COG0629	single-stranded DNA binding
CDIF29627_RS19460	COG0360	Binds together with S18 to 16S ribosomal RNA
CDIF29627_RS19465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS19480	COG0425	Belongs to the sulfur carrier protein TusA family
CDIF29627_RS19495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDIF29627_RS19510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29627_RS19515	COG0583	DNA-binding transcription factor activity
CDIF29627_RS19525	COG1104	cysteine desulfurase activity
CDIF29627_RS19530	COG1475	DNA binding
CDIF29627_RS19535	COG1192	Involved in chromosome partitioning
CDIF29627_RS19540	COG1475	DNA binding
CDIF29627_RS19545	COG0357	Ribosomal RNA small subunit methyltransferase G
CDIF29627_RS19550	COG0445	tRNA wobble uridine modification
CDIF29627_RS19555	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDIF29627_RS19560	COG1847	R3H domain protein
CDIF29627_RS19565	COG0706	membrane insertase activity
CDIF29627_RS19570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDIF29627_RS19575	COG0594	ribonuclease P activity
CDIF29627_RS19580	COG0230	Belongs to the bacterial ribosomal protein bL34 family