locus-tag	class	description
CDIF29745_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDIF29745_RS00010	COG0592	DNA-directed DNA polymerase activity
CDIF29745_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDIF29745_RS00025	COG0187	DNA topoisomerase II activity
CDIF29745_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDIF29745_RS00045	COG1366	Belongs to the anti-sigma-factor antagonist family
CDIF29745_RS00055	COG1191	sigma factor activity
CDIF29745_RS00105	COG1827	regulation of RNA biosynthetic process
CDIF29745_RS00110	COG0668	transmembrane transport
CDIF29745_RS00115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDIF29745_RS00120	COG0590	tRNA wobble adenosine to inosine editing
CDIF29745_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDIF29745_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDIF29745_RS00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDIF29745_RS00155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29745_RS00395	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDIF29745_RS00400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDIF29745_RS00405	COG4463	regulation of RNA biosynthetic process
CDIF29745_RS00410	COG3880	PFAM UvrB UvrC protein
CDIF29745_RS00415	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CDIF29745_RS00420	COG0542	response to heat
CDIF29745_RS00425	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDIF29745_RS00430	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CDIF29745_RS00435	COG4956	integral membrane protein (PIN domain superfamily)
CDIF29745_RS00455	COG3507	Belongs to the glycosyl hydrolase 43 family
CDIF29745_RS00465	COG2390	Transcriptional regulator
CDIF29745_RS00470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDIF29745_RS00475	COG0022	dehydrogenase e1 component
CDIF29745_RS00480	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDIF29745_RS00485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDIF29745_RS00490	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS00490	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS00500	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29745_RS00505	COG3775	system Galactitol-specific IIC component
CDIF29745_RS00520	COG0095	Lipoate-protein ligase
CDIF29745_RS00525	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDIF29745_RS00530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDIF29745_RS00535	COG0442	prolyl-tRNA aminoacylation
CDIF29745_RS00540	COG0442	prolyl-tRNA aminoacylation
CDIF29745_RS00545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDIF29745_RS00555	COG0215	cysteine-tRNA ligase activity
CDIF29745_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDIF29745_RS00575	COG3688	RNA-binding protein containing a PIN domain
CDIF29745_RS00585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDIF29745_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDIF29745_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
CDIF29745_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDIF29745_RS00610	COG0081	regulation of translation
CDIF29745_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDIF29745_RS00620	COG0222	ribosome binding
CDIF29745_RS00630	COG0085	RNA polymerase activity
CDIF29745_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDIF29745_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDIF29745_RS00645	COG0049	tRNA binding
CDIF29745_RS00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDIF29745_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDIF29745_RS00660	COG0051	transcription antitermination factor activity, RNA binding
CDIF29745_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDIF29745_RS00670	COG0088	Forms part of the polypeptide exit tunnel
CDIF29745_RS00675	COG0089	rRNA binding
CDIF29745_RS00680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDIF29745_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDIF29745_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDIF29745_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDIF29745_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDIF29745_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
CDIF29745_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDIF29745_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDIF29745_RS00720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDIF29745_RS00725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDIF29745_RS00730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDIF29745_RS00735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDIF29745_RS00740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDIF29745_RS00745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDIF29745_RS00750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDIF29745_RS00755	COG1841	ribosomal large subunit assembly
CDIF29745_RS00760	COG0200	Binds to the 23S rRNA
CDIF29745_RS00770	COG0563	adenylate kinase activity
CDIF29745_RS00775	COG0024	Methionine aminopeptidase
CDIF29745_RS00785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDIF29745_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDIF29745_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDIF29745_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDIF29745_RS00805	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDIF29745_RS00810	COG0202	RNA polymerase activity
CDIF29745_RS00815	COG0203	ribosomal protein L17
CDIF29745_RS00820	COG1122	ATPase activity
CDIF29745_RS00825	COG1122	ATPase activity
CDIF29745_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDIF29745_RS00835	COG0101	tRNA pseudouridine synthase activity
CDIF29745_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDIF29745_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDIF29745_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS01095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDIF29745_RS01110	COG0280	phosphate acetyltransferase
CDIF29745_RS01145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29745_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDIF29745_RS01155	COG2897	thiosulfate sulfurtransferase activity
CDIF29745_RS01165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDIF29745_RS01170	COG2385	sporulation resulting in formation of a cellular spore
CDIF29745_RS01180	COG1609	Transcriptional regulator
CDIF29745_RS01185	COG1077	Cell shape determining protein MreB Mrl
CDIF29745_RS01190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDIF29745_RS01200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDIF29745_RS01205	COG3949	Membrane
CDIF29745_RS01210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDIF29745_RS01215	COG1040	competence protein
CDIF29745_RS01220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS01220	COG3711	transcriptional antiterminator
CDIF29745_RS01225	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29745_RS01230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS01235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS01245	COG1446	asparaginase
CDIF29745_RS01250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS01255	COG3142	Participates in the control of copper homeostasis
CDIF29745_RS01260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDIF29745_RS01265	COG0653	protein targeting
CDIF29745_RS01270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CDIF29745_RS01275	COG2183	response to ionizing radiation
CDIF29745_RS01280	COG1228	amidohydrolase
CDIF29745_RS01295	COG0802	atpase or kinase
CDIF29745_RS01300	COG1214	PFAM Peptidase M22, glycoprotease
CDIF29745_RS01305	COG0456	acetyltransferase
CDIF29745_RS01310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDIF29745_RS01325	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDIF29745_RS01345	COG1136	(ABC) transporter
CDIF29745_RS01360	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS01365	COG5002	protein histidine kinase activity
CDIF29745_RS01370	COG1136	(ABC) transporter
CDIF29745_RS01370	COG0577	efflux transmembrane transporter activity
CDIF29745_RS01390	COG1473	amidohydrolase
CDIF29745_RS01410	COG0534	Mate efflux family protein
CDIF29745_RS01415	COG0488	(ABC) transporter
CDIF29745_RS01420	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDIF29745_RS01430	COG2221	Nitrite and sulphite reductase 4Fe-4S
CDIF29745_RS01440	COG1151	hydroxylamine reductase activity
CDIF29745_RS01455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDIF29745_RS01490	COG0540	Belongs to the ATCase OTCase family
CDIF29745_RS01495	COG0543	2 iron, 2 sulfur cluster binding
CDIF29745_RS01500	COG0167	dihydroorotate dehydrogenase activity
CDIF29745_RS01505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDIF29745_RS01515	COG0583	DNA-binding transcription factor activity
CDIF29745_RS01530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDIF29745_RS01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDIF29745_RS01540	COG0459	protein refolding
CDIF29745_RS01545	COG1691	(AIR) carboxylase
CDIF29745_RS01550	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDIF29745_RS01555	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDIF29745_RS01560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDIF29745_RS01560	COG0519	Catalyzes the synthesis of GMP from XMP
CDIF29745_RS01595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29745_RS01600	COG2200	EAL domain
CDIF29745_RS01600	COG2771	luxR family
CDIF29745_RS01615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS01620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS01630	COG1011	Hydrolase
CDIF29745_RS01645	COG0778	Nitroreductase
CDIF29745_RS01650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDIF29745_RS01655	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDIF29745_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDIF29745_RS01665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDIF29745_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDIF29745_RS01675	COG0138	bifunctional purine biosynthesis protein purh
CDIF29745_RS01680	COG0151	Belongs to the GarS family
CDIF29745_RS01685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDIF29745_RS01695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDIF29745_RS01710	COG0741	lytic transglycosylase activity
CDIF29745_RS01745	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CDIF29745_RS01750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDIF29745_RS01765	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDIF29745_RS01775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDIF29745_RS01785	COG0463	Glycosyl transferase, family 2
CDIF29745_RS01820	COG4786	Flagellar basal body rod
CDIF29745_RS01830	COG1677	Flagellar hook-basal body complex protein FliE
CDIF29745_RS01835	COG1766	The M ring may be actively involved in energy transduction
CDIF29745_RS01840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDIF29745_RS01850	COG1157	protein secretion by the type III secretion system
CDIF29745_RS01865	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDIF29745_RS01870	COG4786	Flagellar basal body rod
CDIF29745_RS01880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDIF29745_RS01885	COG1360	Flagellar Motor Protein
CDIF29745_RS01900	COG1338	Plays a role in the flagellum-specific transport system
CDIF29745_RS01910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDIF29745_RS01915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDIF29745_RS01920	COG1419	protein localization to endoplasmic reticulum
CDIF29745_RS01930	COG1191	sigma factor activity
CDIF29745_RS01945	COG4786	Flagellar basal body rod
CDIF29745_RS01960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDIF29745_RS01960	COG1776	CheC inhibitor of MCP methylation
CDIF29745_RS01975	COG1454	alcohol dehydrogenase
CDIF29745_RS01980	COG1533	DNA photolyase activity
CDIF29745_RS01995	COG1733	regulation of RNA biosynthetic process
CDIF29745_RS02015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29745_RS02020	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS02020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS02025	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS02025	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS02050	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29745_RS02060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS02095	COG0813	purine-nucleoside phosphorylase activity
CDIF29745_RS02150	COG1131	(ABC) transporter
CDIF29745_RS02170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDIF29745_RS02175	COG1609	Transcriptional regulator
CDIF29745_RS02180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDIF29745_RS02185	COG1879	ABC-type sugar transport system periplasmic component
CDIF29745_RS02190	COG1129	ABC transporter
CDIF29745_RS02195	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDIF29745_RS02200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS02210	COG1473	amidohydrolase
CDIF29745_RS02260	COG2217	Heavy metal translocating P-type atpase
CDIF29745_RS02280	COG0586	Pfam SNARE associated Golgi protein
CDIF29745_RS02310	COG2205	protein histidine kinase activity
CDIF29745_RS02315	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS02340	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CDIF29745_RS02350	COG1122	ATPase activity
CDIF29745_RS02355	COG0210	DNA helicase
CDIF29745_RS02360	COG1362	aminopeptidase activity
CDIF29745_RS02370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDIF29745_RS02385	COG1454	alcohol dehydrogenase
CDIF29745_RS02385	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29745_RS02395	COG1136	(ABC) transporter
CDIF29745_RS02405	COG3290	protein histidine kinase activity
CDIF29745_RS02435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDIF29745_RS02440	COG2357	RelA SpoT domain protein
CDIF29745_RS02460	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CDIF29745_RS02485	COG1263	PTS System
CDIF29745_RS02485	COG2190	(PTS) system
CDIF29745_RS02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS02490	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS02495	COG3711	transcriptional antiterminator
CDIF29745_RS02505	COG0367	asparagine synthase
CDIF29745_RS02520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDIF29745_RS02545	COG1960	acyl-CoA dehydrogenase activity
CDIF29745_RS02550	COG2086	electron transfer activity
CDIF29745_RS02555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29745_RS02560	COG3829	transcription factor binding
CDIF29745_RS02565	COG0191	fructose-bisphosphate aldolase activity
CDIF29745_RS02575	COG1187	pseudouridine synthase activity
CDIF29745_RS02620	COG3254	rhamnose metabolic process
CDIF29745_RS02635	COG1070	Carbohydrate kinase
CDIF29745_RS02640	COG4806	L-rhamnose isomerase
CDIF29745_RS02645	COG0235	Class ii aldolase
CDIF29745_RS02650	COG1757	Na H antiporter
CDIF29745_RS02665	COG3829	transcription factor binding
CDIF29745_RS02670	COG3804	dihydrodipicolinate reductase
CDIF29745_RS02680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDIF29745_RS02690	COG5012	cobalamin binding
CDIF29745_RS02700	COG3457	Alanine racemase
CDIF29745_RS02705	COG1757	Na H antiporter
CDIF29745_RS02740	COG3973	AAA domain
CDIF29745_RS02750	COG1136	(ABC) transporter
CDIF29745_RS02760	COG5002	protein histidine kinase activity
CDIF29745_RS02765	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS02770	COG1309	transcriptional regulator
CDIF29745_RS02785	COG1737	Transcriptional regulator
CDIF29745_RS02795	COG0561	phosphatase activity
CDIF29745_RS02800	COG0366	Alpha amylase catalytic
CDIF29745_RS02805	COG2190	(PTS) system
CDIF29745_RS02805	COG1263	PTS System
CDIF29745_RS02805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS02820	COG0768	penicillin binding
CDIF29745_RS02835	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDIF29745_RS02865	COG1131	(ABC) transporter
CDIF29745_RS02885	COG5002	protein histidine kinase activity
CDIF29745_RS02890	COG0577	efflux transmembrane transporter activity
CDIF29745_RS02890	COG1136	(ABC) transporter
CDIF29745_RS02895	COG1136	(ABC) transporter
CDIF29745_RS02900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDIF29745_RS02910	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS02915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDIF29745_RS02930	COG1063	alcohol dehydrogenase
CDIF29745_RS02940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS02950	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29745_RS02970	COG1686	Belongs to the peptidase S11 family
CDIF29745_RS02975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS02975	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS02995	COG2205	protein histidine kinase activity
CDIF29745_RS03020	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29745_RS03025	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDIF29745_RS03050	COG2378	regulation of single-species biofilm formation
CDIF29745_RS03060	COG2201	protein-glutamate methylesterase activity
CDIF29745_RS03065	COG1776	CheC inhibitor of MCP methylation
CDIF29745_RS03070	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDIF29745_RS03075	COG0835	chemotaxis
CDIF29745_RS03085	COG0840	transmembrane signaling receptor activity
CDIF29745_RS03090	COG0643	Histidine kinase
CDIF29745_RS03090	COG2198	Histidine kinase
CDIF29745_RS03095	COG0835	chemotaxis
CDIF29745_RS03105	COG2201	protein-glutamate methylesterase activity
CDIF29745_RS03155	COG2339	peptidase activity
CDIF29745_RS03160	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CDIF29745_RS03160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDIF29745_RS03165	COG0681	Belongs to the peptidase S26 family
CDIF29745_RS03180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDIF29745_RS03185	COG2066	Belongs to the glutaminase family
CDIF29745_RS03195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDIF29745_RS03215	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDIF29745_RS03220	COG1067	ATP-dependent peptidase activity
CDIF29745_RS03225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDIF29745_RS03230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDIF29745_RS03245	COG1744	ABC transporter substrate-binding protein PnrA-like
CDIF29745_RS03270	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDIF29745_RS03315	COG1309	transcriptional regulator
CDIF29745_RS03320	COG0574	Belongs to the PEP-utilizing enzyme family
CDIF29745_RS03320	COG3848	Pyruvate phosphate dikinase
CDIF29745_RS03335	COG3706	GGDEF domain
CDIF29745_RS03395	COG3969	phosphoadenosine phosphosulfate
CDIF29745_RS03400	COG1475	DNA binding
CDIF29745_RS03415	COG3546	catalase activity
CDIF29745_RS03430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDIF29745_RS03450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDIF29745_RS03490	COG3279	Response regulator of the LytR AlgR family
CDIF29745_RS03495	COG0577	efflux transmembrane transporter activity
CDIF29745_RS03500	COG1136	(ABC) transporter
CDIF29745_RS03520	COG4978	Transcriptional regulator
CDIF29745_RS03520	COG0789	Transcriptional regulator
CDIF29745_RS03570	COG0305	Participates in initiation and elongation during chromosome replication
CDIF29745_RS03590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDIF29745_RS03595	COG0534	Mate efflux family protein
CDIF29745_RS03610	COG4335	DNA alkylation repair
CDIF29745_RS03670	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS03675	COG2205	protein histidine kinase activity
CDIF29745_RS03680	COG1131	(ABC) transporter
CDIF29745_RS03690	COG3177	Filamentation induced by cAMP protein fic
CDIF29745_RS03695	COG1802	Transcriptional regulator
CDIF29745_RS03700	COG4946	Tricorn protease homolog
CDIF29745_RS03700	COG1506	peptidase
CDIF29745_RS03700	COG0823	Involved in the tonB-independent uptake of proteins
CDIF29745_RS03705	COG1506	peptidase
CDIF29745_RS03705	COG4946	Tricorn protease homolog
CDIF29745_RS03705	COG0823	Involved in the tonB-independent uptake of proteins
CDIF29745_RS03725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS03745	COG0038	chloride channel
CDIF29745_RS03830	COG2205	protein histidine kinase activity
CDIF29745_RS03870	COG1595	DNA-templated transcription, initiation
CDIF29745_RS03885	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDIF29745_RS03905	COG2814	Major facilitator Superfamily
CDIF29745_RS03910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDIF29745_RS03915	COG1609	Transcriptional regulator
CDIF29745_RS03930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDIF29745_RS03935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDIF29745_RS03965	COG0789	Transcriptional regulator
CDIF29745_RS03985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDIF29745_RS03990	COG0569	domain protein
CDIF29745_RS03995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDIF29745_RS04000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDIF29745_RS04005	COG0072	phenylalanine-tRNA ligase activity
CDIF29745_RS04005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29745_RS04020	COG0826	peptidase U32
CDIF29745_RS04030	COG1051	belongs to the nudix hydrolase family
CDIF29745_RS04040	COG3706	GGDEF domain
CDIF29745_RS04045	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29745_RS04050	COG1193	negative regulation of DNA recombination
CDIF29745_RS04055	COG1683	Conserved Protein
CDIF29745_RS04060	COG0018	arginyl-trna synthetase
CDIF29745_RS04075	COG1032	radical SAM domain protein
CDIF29745_RS04090	COG0583	DNA-binding transcription factor activity
CDIF29745_RS04100	COG0280	phosphate acetyltransferase
CDIF29745_RS04105	COG1151	hydroxylamine reductase activity
CDIF29745_RS04115	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CDIF29745_RS04120	COG3404	Formiminotransferase-cyclodeaminase
CDIF29745_RS04125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDIF29745_RS04135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDIF29745_RS04135	COG0646	methionine synthase
CDIF29745_RS04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDIF29745_RS04170	COG0509	glycine decarboxylation via glycine cleavage system
CDIF29745_RS04190	COG0095	Lipoate-protein ligase
CDIF29745_RS04210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29745_RS04235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDIF29745_RS04240	COG1360	Flagellar Motor Protein
CDIF29745_RS04260	COG0210	DNA helicase
CDIF29745_RS04265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDIF29745_RS04270	COG0765	amino acid transport
CDIF29745_RS04275	COG1126	abc transporter atp-binding protein
CDIF29745_RS04285	COG0301	tRNA thio-modification
CDIF29745_RS04295	COG0778	Nitroreductase
CDIF29745_RS04300	COG3300	MHYT domain
CDIF29745_RS04300	COG5001	Diguanylate cyclase
CDIF29745_RS04305	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDIF29745_RS04315	COG0530	calcium, potassium:sodium antiporter activity
CDIF29745_RS04320	COG0513	Belongs to the DEAD box helicase family
CDIF29745_RS04340	COG3732	PTS system glucitol sorbitol-specific
CDIF29745_RS04355	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29745_RS04360	COG0243	molybdopterin cofactor binding
CDIF29745_RS04365	COG1366	Belongs to the anti-sigma-factor antagonist family
CDIF29745_RS04370	COG2172	sigma factor antagonist activity
CDIF29745_RS04375	COG1191	sigma factor activity
CDIF29745_RS04385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDIF29745_RS04410	COG1473	amidohydrolase
CDIF29745_RS04420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDIF29745_RS04430	COG0750	zinc metalloprotease
CDIF29745_RS04435	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS04440	COG0488	(ABC) transporter
CDIF29745_RS04455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDIF29745_RS04470	COG1739	Uncharacterized protein family UPF0029
CDIF29745_RS04480	COG0730	response to heat
CDIF29745_RS04485	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDIF29745_RS04490	COG0217	transcriptional regulatory protein
CDIF29745_RS04500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDIF29745_RS04515	COG1024	Enoyl-CoA hydratase
CDIF29745_RS04520	COG2610	gluconate transmembrane transporter activity
CDIF29745_RS04535	COG2086	electron transfer activity
CDIF29745_RS04540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29745_RS04570	COG3300	MHYT domain
CDIF29745_RS04570	COG5001	Diguanylate cyclase
CDIF29745_RS04585	COG2186	Transcriptional regulator
CDIF29745_RS04590	COG2814	Major facilitator Superfamily
CDIF29745_RS04595	COG1263	PTS System
CDIF29745_RS04595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS04595	COG2190	(PTS) system
CDIF29745_RS04600	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS04610	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS04615	COG2205	protein histidine kinase activity
CDIF29745_RS04635	COG1592	Rubrerythrin
CDIF29745_RS04645	COG2033	superoxide reductase activity
CDIF29745_RS04650	COG0069	glutamate synthase activity
CDIF29745_RS04670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDIF29745_RS04680	COG0473	3-isopropylmalate dehydrogenase activity
CDIF29745_RS04685	COG1846	Transcriptional regulator
CDIF29745_RS04710	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDIF29745_RS04715	COG0138	bifunctional purine biosynthesis protein purh
CDIF29745_RS04725	COG0297	glycogen (starch) synthase activity
CDIF29745_RS04725	COG0438	transferase activity, transferring glycosyl groups
CDIF29745_RS04755	COG1473	amidohydrolase
CDIF29745_RS04760	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDIF29745_RS04775	COG0601	transmembrane transport
CDIF29745_RS04780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDIF29745_RS04790	COG0444	Belongs to the ABC transporter superfamily
CDIF29745_RS04795	COG4608	Belongs to the ABC transporter superfamily
CDIF29745_RS04800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS04800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS04815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS04825	COG1486	melibiose metabolic process
CDIF29745_RS04835	COG1073	alpha beta
CDIF29745_RS04845	COG1910	domain protein
CDIF29745_RS04850	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDIF29745_RS04855	COG4149	molybdate abc transporter
CDIF29745_RS04860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDIF29745_RS04865	COG0110	maltose O-acetyltransferase activity
CDIF29745_RS04875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDIF29745_RS04880	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDIF29745_RS04885	COG2984	ABC transporter substrate binding protein
CDIF29745_RS04895	COG4120	Belongs to the binding-protein-dependent transport system permease family
CDIF29745_RS04900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDIF29745_RS04900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDIF29745_RS04915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDIF29745_RS04920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDIF29745_RS04925	COG0297	glycogen (starch) synthase activity
CDIF29745_RS04930	COG0058	SHG alpha-glucan phosphorylase activity
CDIF29745_RS04940	COG1802	Transcriptional regulator
CDIF29745_RS04945	COG1982	Orn Lys Arg decarboxylase major
CDIF29745_RS04950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDIF29745_RS04955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDIF29745_RS04960	COG0010	Belongs to the arginase family
CDIF29745_RS04995	COG4868	Belongs to the UPF0371 family
CDIF29745_RS05000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDIF29745_RS05010	COG1174	glycine betaine transport
CDIF29745_RS05015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDIF29745_RS05045	COG0534	Mate efflux family protein
CDIF29745_RS05050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDIF29745_RS05050	COG0539	negative regulation of cytoplasmic translation
CDIF29745_RS05055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29745_RS05065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDIF29745_RS05070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDIF29745_RS05075	COG0066	3-isopropylmalate dehydratase activity
CDIF29745_RS05080	COG0473	3-isopropylmalate dehydrogenase activity
CDIF29745_RS05095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDIF29745_RS05110	COG3447	MASE1 domain protein
CDIF29745_RS05110	COG5002	protein histidine kinase activity
CDIF29745_RS05110	COG5001	Diguanylate cyclase
CDIF29745_RS05135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDIF29745_RS05140	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDIF29745_RS05150	COG0281	malic enzyme
CDIF29745_RS05175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDIF29745_RS05180	COG0363	glucosamine-6-phosphate deaminase activity
CDIF29745_RS05195	COG5002	protein histidine kinase activity
CDIF29745_RS05200	COG5001	Diguanylate cyclase
CDIF29745_RS05210	COG4978	Transcriptional regulator
CDIF29745_RS05210	COG0789	Transcriptional regulator
CDIF29745_RS05220	COG1132	(ABC) transporter
CDIF29745_RS05240	COG2364	Membrane
CDIF29745_RS05250	COG3842	ATPase activity
CDIF29745_RS05255	COG1176	ABC-type spermidine putrescine transport system, permease component I
CDIF29745_RS05260	COG1177	transmembrane transport
CDIF29745_RS05265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CDIF29745_RS05275	COG5298	Protein conserved in bacteria
CDIF29745_RS05280	COG1215	transferase activity, transferring glycosyl groups
CDIF29745_RS05295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDIF29745_RS05320	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS05330	COG0210	DNA helicase
CDIF29745_RS05340	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CDIF29745_RS05345	COG1074	ATP-dependent DNA helicase activity
CDIF29745_RS05350	COG0420	3'-5' exonuclease activity
CDIF29745_RS05355	COG0419	ATPase involved in DNA repair
CDIF29745_RS05360	COG4536	flavin adenine dinucleotide binding
CDIF29745_RS05370	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29745_RS05380	COG0622	Phosphoesterase
CDIF29745_RS05385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDIF29745_RS05390	COG1131	(ABC) transporter
CDIF29745_RS05410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDIF29745_RS05415	COG1960	acyl-CoA dehydrogenase activity
CDIF29745_RS05420	COG2086	electron transfer activity
CDIF29745_RS05425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29745_RS05440	COG0183	Belongs to the thiolase family
CDIF29745_RS05445	COG0564	pseudouridine synthase activity
CDIF29745_RS05455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDIF29745_RS05510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29745_RS05515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS05520	COG4224	UPF0291 protein
CDIF29745_RS05525	COG1362	aminopeptidase activity
CDIF29745_RS05530	COG2188	Transcriptional regulator
CDIF29745_RS05550	COG3715	PTS system
CDIF29745_RS05555	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29745_RS05560	COG0583	DNA-binding transcription factor activity
CDIF29745_RS05580	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29745_RS05585	COG1132	(ABC) transporter
CDIF29745_RS05595	COG1473	amidohydrolase
CDIF29745_RS05610	COG3279	Response regulator of the LytR AlgR family
CDIF29745_RS05625	COG1882	Formate acetyltransferase
CDIF29745_RS05630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDIF29745_RS05635	COG1396	sequence-specific DNA binding
CDIF29745_RS05660	COG2207	Transcriptional regulator
CDIF29745_RS05660	COG3708	Transcriptional regulator
CDIF29745_RS05680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDIF29745_RS05680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDIF29745_RS05685	COG0237	dephospho-CoA kinase activity
CDIF29745_RS05710	COG0346	lactoylglutathione lyase activity
CDIF29745_RS05715	COG0791	NLP P60 protein
CDIF29745_RS05725	COG4656	Part of a membrane complex involved in electron transport
CDIF29745_RS05730	COG4658	electron transport chain
CDIF29745_RS05735	COG4659	FMN binding
CDIF29745_RS05740	COG4660	Part of a membrane complex involved in electron transport
CDIF29745_RS05745	COG4657	Part of a membrane complex involved in electron transport
CDIF29745_RS05750	COG2878	Part of a membrane complex involved in electron transport
CDIF29745_RS05750	COG1245	4Fe-4S binding domain
CDIF29745_RS05760	COG0424	maF-like protein
CDIF29745_RS05765	COG2003	Belongs to the UPF0758 family
CDIF29745_RS05770	COG1077	Cell shape determining protein MreB Mrl
CDIF29745_RS05790	COG0850	regulation of cytokinetic process
CDIF29745_RS05795	COG2894	cell division
CDIF29745_RS05800	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDIF29745_RS05805	COG0772	Belongs to the SEDS family
CDIF29745_RS05810	COG1803	Methylglyoxal synthase
CDIF29745_RS05815	COG1695	Transcriptional regulator
CDIF29745_RS05830	COG0426	domain, Protein
CDIF29745_RS05850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDIF29745_RS05860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDIF29745_RS05865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDIF29745_RS05875	COG0460	homoserine dehydrogenase
CDIF29745_RS05885	COG3314	Sporulation integral membrane protein YlbJ
CDIF29745_RS05890	COG2186	Transcriptional regulator
CDIF29745_RS05895	COG3875	lactate racemase activity
CDIF29745_RS05900	COG2086	electron transfer activity
CDIF29745_RS05905	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDIF29745_RS05910	COG0277	FAD linked oxidase domain protein
CDIF29745_RS05915	COG1323	Belongs to the UPF0348 family
CDIF29745_RS05920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDIF29745_RS05930	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDIF29745_RS05940	COG0416	fatty acid biosynthetic process
CDIF29745_RS05945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDIF29745_RS05955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDIF29745_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29745_RS05965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDIF29745_RS05970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDIF29745_RS05975	COG3706	GGDEF domain
CDIF29745_RS05990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDIF29745_RS06005	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CDIF29745_RS06010	COG3854	ATPases associated with a variety of cellular activities
CDIF29745_RS06050	COG1302	Protein conserved in bacteria
CDIF29745_RS06055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDIF29745_RS06060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDIF29745_RS06065	COG1570	exodeoxyribonuclease VII activity
CDIF29745_RS06080	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CDIF29745_RS06085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDIF29745_RS06090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDIF29745_RS06095	COG0497	DNA recombination
CDIF29745_RS06105	COG0456	acetyltransferase
CDIF29745_RS06110	COG0456	acetyltransferase
CDIF29745_RS06115	COG0750	zinc metalloprotease
CDIF29745_RS06135	COG0463	Glycosyl transferase, family 2
CDIF29745_RS06150	COG0494	nUDIX hydrolase
CDIF29745_RS06160	COG4974	Belongs to the 'phage' integrase family
CDIF29745_RS06165	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDIF29745_RS06170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDIF29745_RS06180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDIF29745_RS06185	COG4122	O-methyltransferase activity
CDIF29745_RS06190	COG0826	peptidase U32
CDIF29745_RS06195	COG0768	penicillin binding
CDIF29745_RS06225	COG1476	TRANSCRIPTIONal
CDIF29745_RS06275	COG1484	DNA-dependent DNA replication
CDIF29745_RS06435	COG3617	BRO family, N-terminal domain
CDIF29745_RS06455	COG4193	domain, Protein
CDIF29745_RS06465	COG3628	GPW Gp25 family protein
CDIF29745_RS06470	COG3299	homolog of phage Mu protein gp47
CDIF29745_RS06515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDIF29745_RS06590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDIF29745_RS06600	COG0571	ribonuclease III activity
CDIF29745_RS06610	COG1196	nuclear chromosome segregation
CDIF29745_RS06615	COG0552	protein localization to endoplasmic reticulum
CDIF29745_RS06625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDIF29745_RS06630	COG0228	four-way junction DNA binding
CDIF29745_RS06640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDIF29745_RS06645	COG0336	Belongs to the RNA methyltransferase TrmD family
CDIF29745_RS06650	COG0335	large ribosomal subunit rRNA binding
CDIF29745_RS06660	COG1114	Component of the transport system for branched-chain amino acids
CDIF29745_RS06675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDIF29745_RS06705	COG1131	(ABC) transporter
CDIF29745_RS06710	COG2197	response regulator
CDIF29745_RS06715	COG4585	Histidine kinase
CDIF29745_RS06720	COG0792	nuclease activity
CDIF29745_RS06725	COG0606	chelatase, subunit chli
CDIF29745_RS06730	COG0758	DNA mediated transformation
CDIF29745_RS06735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDIF29745_RS06745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDIF29745_RS06755	COG1959	2 iron, 2 sulfur cluster binding
CDIF29745_RS06765	COG0822	iron-sulfur transferase activity
CDIF29745_RS06770	COG0482	sulfurtransferase activity
CDIF29745_RS06775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDIF29745_RS06780	COG4472	Bacterial protein of unknown function (DUF965)
CDIF29745_RS06790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDIF29745_RS06795	COG3906	Belongs to the UPF0473 family
CDIF29745_RS06800	COG0735	belongs to the Fur family
CDIF29745_RS06810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDIF29745_RS06820	COG1686	Belongs to the peptidase S11 family
CDIF29745_RS06830	COG1917	Cupin 2, conserved barrel domain protein
CDIF29745_RS06830	COG2207	Transcriptional regulator
CDIF29745_RS06835	COG1994	Peptidase M50
CDIF29745_RS06845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDIF29745_RS06900	COG0779	Required for maturation of 30S ribosomal subunits
CDIF29745_RS06905	COG0195	Participates in both transcription termination and antitermination
CDIF29745_RS06910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CDIF29745_RS06920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDIF29745_RS06950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDIF29745_RS06955	COG0196	riboflavin kinase activity
CDIF29745_RS06965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDIF29745_RS06970	COG1307	EDD domain protein, DegV family
CDIF29745_RS06975	COG1185	polyribonucleotide nucleotidyltransferase activity
CDIF29745_RS06980	COG0726	polysaccharide deacetylase
CDIF29745_RS06985	COG0612	Peptidase, M16
CDIF29745_RS06990	COG1873	PFAM PRC-barrel domain
CDIF29745_RS06995	COG0527	aspartate kinase activity
CDIF29745_RS07000	COG0740	serine-type endopeptidase activity
CDIF29745_RS07010	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CDIF29745_RS07015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29745_RS07025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDIF29745_RS07030	COG1418	mRNA catabolic process
CDIF29745_RS07045	COG1968	undecaprenyl-diphosphatase activity
CDIF29745_RS07055	COG0114	fumarate hydratase activity
CDIF29745_RS07065	COG0436	Aminotransferase
CDIF29745_RS07075	COG0708	Exodeoxyribonuclease III
CDIF29745_RS07090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29745_RS07115	COG1131	(ABC) transporter
CDIF29745_RS07145	COG1278	Cold shock
CDIF29745_RS07155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDIF29745_RS07235	COG3299	homolog of phage Mu protein gp47
CDIF29745_RS07270	COG1396	sequence-specific DNA binding
CDIF29745_RS07275	COG2814	Major facilitator Superfamily
CDIF29745_RS07285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDIF29745_RS07290	COG3273	potassium ion transport
CDIF29745_RS07290	COG0471	metal ion transport
CDIF29745_RS07295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDIF29745_RS07300	COG1914	H( )-stimulated, divalent metal cation uptake system
CDIF29745_RS07305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDIF29745_RS07310	COG1984	allophanate hydrolase subunit 2
CDIF29745_RS07315	COG1396	sequence-specific DNA binding
CDIF29745_RS07320	COG4948	Mandelate Racemase Muconate Lactonizing
CDIF29745_RS07365	COG1473	amidohydrolase
CDIF29745_RS07370	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDIF29745_RS07385	COG0584	glycerophosphoryl diester phosphodiesterase
CDIF29745_RS07405	COG0488	(ABC) transporter
CDIF29745_RS07415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS07420	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDIF29745_RS07425	COG1058	Belongs to the CinA family
CDIF29745_RS07425	COG1546	Belongs to the CinA family
CDIF29745_RS07440	COG3829	transcription factor binding
CDIF29745_RS07450	COG1242	4 iron, 4 sulfur cluster binding
CDIF29745_RS07495	COG5001	Diguanylate cyclase
CDIF29745_RS07495	COG3447	MASE1 domain protein
CDIF29745_RS07495	COG5002	protein histidine kinase activity
CDIF29745_RS07500	COG2203	Gaf domain
CDIF29745_RS07500	COG2199	diguanylate cyclase activity
CDIF29745_RS07510	COG4978	Transcriptional regulator
CDIF29745_RS07510	COG0789	Transcriptional regulator
CDIF29745_RS07525	COG1285	pathogenesis
CDIF29745_RS07530	COG1335	isochorismatase
CDIF29745_RS07550	COG0726	polysaccharide deacetylase
CDIF29745_RS07565	COG0450	alkyl hydroperoxide reductase
CDIF29745_RS07580	COG2720	vancomycin resistance protein
CDIF29745_RS07585	COG3829	transcription factor binding
CDIF29745_RS07600	COG1346	cytolysis
CDIF29745_RS07605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29745_RS07615	COG2340	Cysteine-rich secretory protein family
CDIF29745_RS07620	COG0726	polysaccharide deacetylase
CDIF29745_RS07625	COG0512	Glutamine amidotransferase of anthranilate synthase
CDIF29745_RS07630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDIF29745_RS07635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDIF29745_RS07645	COG0302	gtp cyclohydrolase
CDIF29745_RS07650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDIF29745_RS07655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDIF29745_RS07660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDIF29745_RS07665	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDIF29745_RS07670	COG0358	DNA primase activity
CDIF29745_RS07675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDIF29745_RS07680	COG2384	SAM-dependent methyltransferase
CDIF29745_RS07685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDIF29745_RS07690	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDIF29745_RS07710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS07725	COG3850	Histidine kinase
CDIF29745_RS07725	COG5002	protein histidine kinase activity
CDIF29745_RS07730	COG0577	efflux transmembrane transporter activity
CDIF29745_RS07730	COG1136	(ABC) transporter
CDIF29745_RS07760	COG1132	(ABC) transporter
CDIF29745_RS07765	COG1132	(ABC) transporter
CDIF29745_RS07770	COG1773	rubredoxin
CDIF29745_RS07770	COG1592	Rubrerythrin
CDIF29745_RS07775	COG0412	Dienelactone hydrolase
CDIF29745_RS07810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29745_RS07845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDIF29745_RS07850	COG2011	ABC-type metal ion transport system permease component
CDIF29745_RS07860	COG5002	protein histidine kinase activity
CDIF29745_RS07865	COG2094	Belongs to the DNA glycosylase MPG family
CDIF29745_RS07870	COG1396	sequence-specific DNA binding
CDIF29745_RS07875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDIF29745_RS07880	COG4086	secreted protein
CDIF29745_RS07915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDIF29745_RS07925	COG1131	(ABC) transporter
CDIF29745_RS07935	COG0534	Mate efflux family protein
CDIF29745_RS07950	COG0348	domain, Protein
CDIF29745_RS07950	COG3901	Regulator of nitric oxide reductase transcription
CDIF29745_RS07980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDIF29745_RS07985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDIF29745_RS07995	COG5001	Diguanylate cyclase
CDIF29745_RS08005	COG0789	Transcriptional regulator
CDIF29745_RS08005	COG4978	Transcriptional regulator
CDIF29745_RS08010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CDIF29745_RS08030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDIF29745_RS08035	COG0726	polysaccharide deacetylase
CDIF29745_RS08045	COG1592	Rubrerythrin
CDIF29745_RS08045	COG1773	rubredoxin
CDIF29745_RS08050	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29745_RS08055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDIF29745_RS08060	COG0577	efflux transmembrane transporter activity
CDIF29745_RS08065	COG1136	(ABC) transporter
CDIF29745_RS08065	COG0577	efflux transmembrane transporter activity
CDIF29745_RS08075	COG2205	protein histidine kinase activity
CDIF29745_RS08080	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS08085	COG1136	(ABC) transporter
CDIF29745_RS08090	COG0577	efflux transmembrane transporter activity
CDIF29745_RS08095	COG0405	Gamma-glutamyltransferase
CDIF29745_RS08110	COG0493	'glutamate synthase
CDIF29745_RS08110	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29745_RS08120	COG1136	(ABC) transporter
CDIF29745_RS08125	COG0577	efflux transmembrane transporter activity
CDIF29745_RS08165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDIF29745_RS08170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDIF29745_RS08175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29745_RS08180	COG0131	Imidazoleglycerol-phosphate dehydratase
CDIF29745_RS08185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDIF29745_RS08190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDIF29745_RS08195	COG0107	imidazoleglycerol-phosphate synthase activity
CDIF29745_RS08200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDIF29745_RS08200	COG0140	phosphoribosyl-ATP diphosphatase activity
CDIF29745_RS08205	COG0531	amino acid
CDIF29745_RS08220	COG1595	DNA-templated transcription, initiation
CDIF29745_RS08235	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDIF29745_RS08315	COG2207	Transcriptional regulator
CDIF29745_RS08315	COG3708	Transcriptional regulator
CDIF29745_RS08325	COG0741	lytic transglycosylase activity
CDIF29745_RS08325	COG0791	NLP P60 protein
CDIF29745_RS08375	COG2946	Replication initiation factor
CDIF29745_RS08385	COG1674	ftsk spoiiie
CDIF29745_RS08395	COG3620	sequence-specific DNA binding
CDIF29745_RS08420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDIF29745_RS08425	COG0028	Belongs to the TPP enzyme family
CDIF29745_RS08430	COG3546	catalase activity
CDIF29745_RS08435	COG1331	Highly conserved protein containing a thioredoxin domain
CDIF29745_RS08445	COG2267	carboxylic ester hydrolase activity
CDIF29745_RS08460	COG1388	LysM domain
CDIF29745_RS08460	COG3584	3D domain protein
CDIF29745_RS08470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29745_RS08475	COG1295	ribonuclease BN
CDIF29745_RS08480	COG5002	protein histidine kinase activity
CDIF29745_RS08485	COG0460	homoserine dehydrogenase
CDIF29745_RS08495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDIF29745_RS08500	COG2267	carboxylic ester hydrolase activity
CDIF29745_RS08505	COG5566	PFAM Mor transcription activator
CDIF29745_RS08515	COG2971	BadF BadG BcrA BcrD
CDIF29745_RS08525	COG1129	ABC transporter
CDIF29745_RS08530	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDIF29745_RS08540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29745_RS08550	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDIF29745_RS08555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDIF29745_RS08560	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CDIF29745_RS08565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDIF29745_RS08570	COG1045	serine acetyltransferase
CDIF29745_RS08575	COG1141	Ferredoxin
CDIF29745_RS08595	COG0351	phosphomethylpyrimidine kinase
CDIF29745_RS08600	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CDIF29745_RS08605	COG0352	thiamine-phosphate diphosphorylase activity
CDIF29745_RS08610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS08630	COG1725	Transcriptional regulator
CDIF29745_RS08660	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29745_RS08670	COG4555	ABC transporter
CDIF29745_RS08675	COG1668	transmembrane transport
CDIF29745_RS08680	COG3300	MHYT domain
CDIF29745_RS08680	COG5001	Diguanylate cyclase
CDIF29745_RS08685	COG1725	Transcriptional regulator
CDIF29745_RS08690	COG1131	(ABC) transporter
CDIF29745_RS08705	COG0668	transmembrane transport
CDIF29745_RS08715	COG0426	domain, Protein
CDIF29745_RS08730	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDIF29745_RS08735	COG1876	peptidase activity
CDIF29745_RS08760	COG0367	asparagine synthase
CDIF29745_RS08780	COG2310	stress, protein
CDIF29745_RS08795	COG3853	Toxic anion resistance protein (TelA)
CDIF29745_RS08825	COG5505	Protein of unknown function (DUF819)
CDIF29745_RS08835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29745_RS08840	COG4605	iron ion homeostasis
CDIF29745_RS08845	COG4604	ABC transporter, ATP-binding protein
CDIF29745_RS08850	COG4607	ABC-type enterochelin transport system periplasmic component
CDIF29745_RS08855	COG5001	Diguanylate cyclase
CDIF29745_RS08855	COG4251	negative regulation of phosphorylation
CDIF29745_RS08855	COG2203	Gaf domain
CDIF29745_RS08855	COG3706	GGDEF domain
CDIF29745_RS08870	COG0095	Lipoate-protein ligase
CDIF29745_RS08875	COG1757	Na H antiporter
CDIF29745_RS08890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDIF29745_RS08895	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDIF29745_RS08900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDIF29745_RS08905	COG3123	guanosine phosphorylase activity
CDIF29745_RS08910	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29745_RS08925	COG1396	sequence-specific DNA binding
CDIF29745_RS08955	COG1131	(ABC) transporter
CDIF29745_RS08965	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS08970	COG2205	protein histidine kinase activity
CDIF29745_RS08990	COG1733	regulation of RNA biosynthetic process
CDIF29745_RS08995	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CDIF29745_RS09025	COG1309	transcriptional regulator
CDIF29745_RS09060	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS09065	COG5002	protein histidine kinase activity
CDIF29745_RS09070	COG3118	belongs to the thioredoxin family
CDIF29745_RS09100	COG1115	amino acid carrier protein
CDIF29745_RS09110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDIF29745_RS09110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDIF29745_RS09125	COG0514	ATP-dependent DNA helicase (RecQ)
CDIF29745_RS09130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDIF29745_RS09145	COG2022	thiamine diphosphate biosynthetic process
CDIF29745_RS09150	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDIF29745_RS09160	COG1288	antiporter activity
CDIF29745_RS09180	COG0393	Putative heavy-metal-binding
CDIF29745_RS09185	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDIF29745_RS09195	COG0315	cyclic pyranopterin monophosphate synthase activity
CDIF29745_RS09285	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDIF29745_RS09290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDIF29745_RS09290	COG2207	Transcriptional regulator
CDIF29745_RS09310	COG5012	cobalamin binding
CDIF29745_RS09315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDIF29745_RS09325	COG1011	Hydrolase
CDIF29745_RS09330	COG1917	Cupin 2, conserved barrel domain protein
CDIF29745_RS09330	COG1396	sequence-specific DNA binding
CDIF29745_RS09335	COG2610	gluconate transmembrane transporter activity
CDIF29745_RS09340	COG5002	protein histidine kinase activity
CDIF29745_RS09345	COG2204	response regulator
CDIF29745_RS09385	COG0786	glutamate:sodium symporter activity
CDIF29745_RS09400	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CDIF29745_RS09405	COG1924	4 iron, 4 sulfur cluster binding
CDIF29745_RS09410	COG2385	sporulation resulting in formation of a cellular spore
CDIF29745_RS09410	COG2247	cell wall binding repeat
CDIF29745_RS09420	COG1309	transcriptional regulator
CDIF29745_RS09445	COG0242	peptide deformylase activity
CDIF29745_RS09480	COG3326	Membrane
CDIF29745_RS09495	COG0494	nUDIX hydrolase
CDIF29745_RS09545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDIF29745_RS09550	COG0765	amino acid transport
CDIF29745_RS09560	COG1393	Belongs to the ArsC family
CDIF29745_RS09570	COG1606	tRNA processing
CDIF29745_RS09575	COG0116	Belongs to the methyltransferase superfamily
CDIF29745_RS09590	COG5002	protein histidine kinase activity
CDIF29745_RS09590	COG3850	Histidine kinase
CDIF29745_RS09600	COG0137	argininosuccinate synthase activity
CDIF29745_RS09610	COG0789	Transcriptional regulator
CDIF29745_RS09620	COG2323	membrane
CDIF29745_RS09635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDIF29745_RS09660	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDIF29745_RS09665	COG0583	DNA-binding transcription factor activity
CDIF29745_RS09680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29745_RS09695	COG1609	Transcriptional regulator
CDIF29745_RS09705	COG1621	beta-fructofuranosidase activity
CDIF29745_RS09710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDIF29745_RS09760	COG1674	ftsk spoiiie
CDIF29745_RS09770	COG2946	Replication initiation factor
CDIF29745_RS09815	COG0741	lytic transglycosylase activity
CDIF29745_RS09815	COG0791	NLP P60 protein
CDIF29745_RS09825	COG3344	reverse transcriptase
CDIF29745_RS09850	COG2375	cellular response to nickel ion
CDIF29745_RS09850	COG1132	(ABC) transporter
CDIF29745_RS09855	COG1132	(ABC) transporter
CDIF29745_RS09860	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS09865	COG3620	sequence-specific DNA binding
CDIF29745_RS09910	COG2814	Major facilitator Superfamily
CDIF29745_RS09940	COG0406	alpha-ribazole phosphatase activity
CDIF29745_RS09945	COG2081	HI0933 family
CDIF29745_RS09950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDIF29745_RS09955	COG0204	Acyl-transferase
CDIF29745_RS09960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDIF29745_RS09975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDIF29745_RS09980	COG3022	response to hydroperoxide
CDIF29745_RS09995	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDIF29745_RS10000	COG1846	Transcriptional regulator
CDIF29745_RS10005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDIF29745_RS10010	COG2205	protein histidine kinase activity
CDIF29745_RS10020	COG0598	Magnesium transport protein CorA
CDIF29745_RS10030	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDIF29745_RS10035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDIF29745_RS10040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDIF29745_RS10045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDIF29745_RS10055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDIF29745_RS10065	COG0287	Prephenate dehydrogenase
CDIF29745_RS10100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDIF29745_RS10105	COG2226	methyltransferase
CDIF29745_RS10110	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CDIF29745_RS10140	COG2131	deaminase
CDIF29745_RS10165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29745_RS10215	COG4303	Ethanolamine ammonia lyase large subunit
CDIF29745_RS10220	COG4302	ethanolamine ammonia-lyase activity
CDIF29745_RS10235	COG1454	alcohol dehydrogenase
CDIF29745_RS10235	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29745_RS10250	COG4869	propanediol catabolic process
CDIF29745_RS10260	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CDIF29745_RS10270	COG3192	ethanolamine utilization protein
CDIF29745_RS10275	COG4766	ethanolamine catabolic process
CDIF29745_RS10290	COG1473	amidohydrolase
CDIF29745_RS10295	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDIF29745_RS10300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29745_RS10305	COG1116	anion transmembrane transporter activity
CDIF29745_RS10325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDIF29745_RS10330	COG4974	Belongs to the 'phage' integrase family
CDIF29745_RS10345	COG2359	stage V sporulation protein S
CDIF29745_RS10350	COG0825	malonyl-CoA metabolic process
CDIF29745_RS10355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDIF29745_RS10360	COG0439	Biotin carboxylase
CDIF29745_RS10365	COG0511	ligase activity, forming carbon-carbon bonds
CDIF29745_RS10385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDIF29745_RS10410	COG1136	(ABC) transporter
CDIF29745_RS10420	COG2205	protein histidine kinase activity
CDIF29745_RS10425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29745_RS10430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDIF29745_RS10450	COG1136	(ABC) transporter
CDIF29745_RS10455	COG2205	protein histidine kinase activity
CDIF29745_RS10460	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS10470	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS10475	COG5002	protein histidine kinase activity
CDIF29745_RS10480	COG0577	efflux transmembrane transporter activity
CDIF29745_RS10480	COG1136	(ABC) transporter
CDIF29745_RS10515	COG1811	Na channel or pump
CDIF29745_RS10520	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CDIF29745_RS10535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS10540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CDIF29745_RS10545	COG1923	regulation of RNA biosynthetic process
CDIF29745_RS10550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDIF29745_RS10555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDIF29745_RS10560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDIF29745_RS10565	COG1116	anion transmembrane transporter activity
CDIF29745_RS10570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDIF29745_RS10575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29745_RS10595	COG0384	phenazine biosynthesis protein PhzF
CDIF29745_RS10600	COG0494	nUDIX hydrolase
CDIF29745_RS10610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29745_RS10615	COG2247	cell wall binding repeat
CDIF29745_RS10615	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS10670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDIF29745_RS10695	COG0730	response to heat
CDIF29745_RS10700	COG2207	Transcriptional regulator
CDIF29745_RS10715	COG0596	Alpha beta hydrolase
CDIF29745_RS10720	COG1309	transcriptional regulator
CDIF29745_RS10735	COG1404	Belongs to the peptidase S8 family
CDIF29745_RS10755	COG0129	dihydroxy-acid dehydratase activity
CDIF29745_RS10785	COG2207	Transcriptional regulator
CDIF29745_RS10790	COG2814	Major facilitator Superfamily
CDIF29745_RS10810	COG1725	Transcriptional regulator
CDIF29745_RS10835	COG1794	racemase activity, acting on amino acids and derivatives
CDIF29745_RS10845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDIF29745_RS10850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDIF29745_RS10855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDIF29745_RS10860	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDIF29745_RS10910	COG1309	transcriptional regulator
CDIF29745_RS11005	COG0741	lytic transglycosylase activity
CDIF29745_RS11005	COG0791	NLP P60 protein
CDIF29745_RS11055	COG2946	Replication initiation factor
CDIF29745_RS11060	COG1674	ftsk spoiiie
CDIF29745_RS11100	COG3655	Transcriptional regulator
CDIF29745_RS11115	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS11120	COG1737	Transcriptional regulator
CDIF29745_RS11125	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CDIF29745_RS11130	COG1187	pseudouridine synthase activity
CDIF29745_RS11135	COG0628	permease
CDIF29745_RS11145	COG0019	diaminopimelate decarboxylase activity
CDIF29745_RS11150	COG0527	aspartate kinase activity
CDIF29745_RS11180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDIF29745_RS11185	COG1597	lipid kinase activity
CDIF29745_RS11215	COG0582	viral genome integration into host DNA
CDIF29745_RS11225	COG0488	(ABC) transporter
CDIF29745_RS11240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDIF29745_RS11250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29745_RS11250	COG2080	2 iron, 2 sulfur cluster binding
CDIF29745_RS11260	COG2233	PERMEase
CDIF29745_RS11275	COG0167	dihydroorotate dehydrogenase activity
CDIF29745_RS11280	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29745_RS11300	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29745_RS11325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29745_RS11350	COG3829	transcription factor binding
CDIF29745_RS11360	COG1401	restriction endodeoxyribonuclease activity
CDIF29745_RS11375	COG4708	membrane
CDIF29745_RS11385	COG2080	2 iron, 2 sulfur cluster binding
CDIF29745_RS11385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29745_RS11420	COG1131	(ABC) transporter
CDIF29745_RS11430	COG2252	PERMEase
CDIF29745_RS11435	COG0534	Mate efflux family protein
CDIF29745_RS11445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDIF29745_RS11450	COG1349	DNA-binding transcription factor activity
CDIF29745_RS11460	COG5002	protein histidine kinase activity
CDIF29745_RS11465	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS11470	COG2217	Heavy metal translocating P-type atpase
CDIF29745_RS11485	COG1217	gtp-binding protein TYPA
CDIF29745_RS11490	COG0492	ferredoxin-NADP+ reductase activity
CDIF29745_RS11530	COG1247	-acetyltransferase
CDIF29745_RS11555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDIF29745_RS11560	COG0750	zinc metalloprotease
CDIF29745_RS11565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDIF29745_RS11590	COG4589	Belongs to the CDS family
CDIF29745_RS11605	COG0233	cytoplasmic translational termination
CDIF29745_RS11610	COG0528	UMP kinase activity
CDIF29745_RS11615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDIF29745_RS11620	COG0052	Belongs to the universal ribosomal protein uS2 family
CDIF29745_RS11625	COG1686	Belongs to the peptidase S11 family
CDIF29745_RS11640	COG1971	Probably functions as a manganese efflux pump
CDIF29745_RS11645	COG1193	negative regulation of DNA recombination
CDIF29745_RS11660	COG2720	vancomycin resistance protein
CDIF29745_RS11680	COG1363	Peptidase, m42
CDIF29745_RS11690	COG1160	GTP binding
CDIF29745_RS11695	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDIF29745_RS11745	COG0039	L-malate dehydrogenase activity
CDIF29745_RS11755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDIF29745_RS11755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDIF29745_RS11765	COG1151	hydroxylamine reductase activity
CDIF29745_RS11785	COG1126	abc transporter atp-binding protein
CDIF29745_RS11810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDIF29745_RS11815	COG0437	4 iron, 4 sulfur cluster binding
CDIF29745_RS11825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDIF29745_RS11830	COG0596	Alpha beta hydrolase
CDIF29745_RS11840	COG0513	Belongs to the DEAD box helicase family
CDIF29745_RS11860	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDIF29745_RS11865	COG1554	hydrolase, family 65, central catalytic
CDIF29745_RS11870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29745_RS11880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDIF29745_RS11890	COG2247	cell wall binding repeat
CDIF29745_RS11890	COG2385	sporulation resulting in formation of a cellular spore
CDIF29745_RS11900	COG1528	Iron-storage protein
CDIF29745_RS11920	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDIF29745_RS11920	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDIF29745_RS11930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29745_RS11945	COG1309	transcriptional regulator
CDIF29745_RS11955	COG0628	permease
CDIF29745_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29745_RS11975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDIF29745_RS12000	COG0288	reversible hydration of carbon dioxide
CDIF29745_RS12020	COG0710	3-dehydroquinate dehydratase activity
CDIF29745_RS12030	COG0582	viral genome integration into host DNA
CDIF29745_RS12055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDIF29745_RS12085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29745_RS12145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDIF29745_RS12150	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29745_RS12155	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CDIF29745_RS12170	COG2203	Gaf domain
CDIF29745_RS12170	COG3706	GGDEF domain
CDIF29745_RS12170	COG4251	negative regulation of phosphorylation
CDIF29745_RS12170	COG5001	Diguanylate cyclase
CDIF29745_RS12175	COG0017	Asparaginyl-tRNA synthetase
CDIF29745_RS12185	COG1404	Belongs to the peptidase S8 family
CDIF29745_RS12190	COG1404	Belongs to the peptidase S8 family
CDIF29745_RS12200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDIF29745_RS12215	COG1509	lysine 2,3-aminomutase activity
CDIF29745_RS12220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS12225	COG1794	racemase activity, acting on amino acids and derivatives
CDIF29745_RS12245	COG0662	Cupin 2, conserved barrel domain protein
CDIF29745_RS12250	COG3104	oligopeptide transport
CDIF29745_RS12255	COG0006	proline dipeptidase activity
CDIF29745_RS12260	COG3104	oligopeptide transport
CDIF29745_RS12265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDIF29745_RS12280	COG0723	plastoquinol--plastocyanin reductase activity
CDIF29745_RS12280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDIF29745_RS12290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS12290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS12290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS12295	COG1105	Belongs to the carbohydrate kinase PfkB family
CDIF29745_RS12300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS12300	COG3711	transcriptional antiterminator
CDIF29745_RS12305	COG2365	Tyrosine phosphatase family
CDIF29745_RS12325	COG1115	amino acid carrier protein
CDIF29745_RS12335	COG0235	Class ii aldolase
CDIF29745_RS12340	COG1063	alcohol dehydrogenase
CDIF29745_RS12345	COG3775	system Galactitol-specific IIC component
CDIF29745_RS12350	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29745_RS12355	COG2213	PTS system mannitol-specific
CDIF29745_RS12355	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS12360	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS12360	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS12370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS12375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDIF29745_RS12385	COG5002	protein histidine kinase activity
CDIF29745_RS12445	COG3617	BRO family, N-terminal domain
CDIF29745_RS12515	COG3620	sequence-specific DNA binding
CDIF29745_RS12540	COG3842	ATPase activity
CDIF29745_RS12560	COG2205	protein histidine kinase activity
CDIF29745_RS12565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29745_RS12570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDIF29745_RS12575	COG0698	ribose 5-phosphate isomerase
CDIF29745_RS12580	COG3958	Transketolase
CDIF29745_RS12585	COG3959	Transketolase, thiamine diphosphate binding domain
CDIF29745_RS12600	COG3775	system Galactitol-specific IIC component
CDIF29745_RS12605	COG3414	Phosphotransferase system galactitol-specific IIB component
CDIF29745_RS12615	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDIF29745_RS12615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDIF29745_RS12620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDIF29745_RS12625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDIF29745_RS12630	COG0246	Mannitol dehydrogenase
CDIF29745_RS12635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS12640	COG3711	transcriptional antiterminator
CDIF29745_RS12650	COG0516	GMP reductase activity
CDIF29745_RS12650	COG0517	IMP dehydrogenase activity
CDIF29745_RS12655	COG3853	Toxic anion resistance protein (TelA)
CDIF29745_RS12665	COG1454	alcohol dehydrogenase
CDIF29745_RS12670	COG0427	acetyl-CoA hydrolase
CDIF29745_RS12685	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29745_RS12690	COG0427	acetyl-CoA hydrolase
CDIF29745_RS12695	COG2985	domain, Protein
CDIF29745_RS12695	COG0490	domain, Protein
CDIF29745_RS12695	COG0490	domain, Protein
CDIF29745_RS12695	COG2985	domain, Protein
CDIF29745_RS12700	COG0583	DNA-binding transcription factor activity
CDIF29745_RS12710	COG0006	proline dipeptidase activity
CDIF29745_RS12740	COG3118	belongs to the thioredoxin family
CDIF29745_RS12760	COG0561	phosphatase activity
CDIF29745_RS12775	COG1116	anion transmembrane transporter activity
CDIF29745_RS12785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29745_RS12825	COG0157	Belongs to the NadC ModD family
CDIF29745_RS12835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDIF29745_RS12840	COG1966	Carbon starvation protein
CDIF29745_RS12855	COG0628	permease
CDIF29745_RS12865	COG2364	Membrane
CDIF29745_RS12870	COG3426	butyrate kinase activity
CDIF29745_RS12895	COG2199	diguanylate cyclase activity
CDIF29745_RS12900	COG2203	Gaf domain
CDIF29745_RS12900	COG2199	diguanylate cyclase activity
CDIF29745_RS12965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29745_RS12965	COG0072	phenylalanine-tRNA ligase activity
CDIF29745_RS12970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDIF29745_RS12975	COG2176	DNA-directed DNA polymerase activity
CDIF29745_RS12995	COG0037	tRNA processing
CDIF29745_RS13010	COG3546	catalase activity
CDIF29745_RS13015	COG0791	NLP P60 protein
CDIF29745_RS13015	COG1388	LysM domain
CDIF29745_RS13015	COG3103	Sh3 type 3 domain protein
CDIF29745_RS13025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDIF29745_RS13025	COG0551	DNA topoisomerase type I activity
CDIF29745_RS13055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDIF29745_RS13055	COG0574	Belongs to the PEP-utilizing enzyme family
CDIF29745_RS13060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDIF29745_RS13065	COG0517	IMP dehydrogenase activity
CDIF29745_RS13085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS13085	COG3711	transcriptional antiterminator
CDIF29745_RS13090	COG3732	PTS system glucitol sorbitol-specific
CDIF29745_RS13100	COG2207	Transcriptional regulator
CDIF29745_RS13115	COG1115	amino acid carrier protein
CDIF29745_RS13120	COG2223	nitrite transmembrane transporter activity
CDIF29745_RS13125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS13130	COG0280	phosphate acetyltransferase
CDIF29745_RS13150	COG0674	pyruvate-flavodoxin oxidoreductase activity
CDIF29745_RS13150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CDIF29745_RS13160	COG1414	Transcriptional regulator
CDIF29745_RS13170	COG0751	glycine-tRNA ligase activity
CDIF29745_RS13175	COG0752	glycyl-tRNA synthetase alpha subunit
CDIF29745_RS13185	COG1381	Involved in DNA repair and RecF pathway recombination
CDIF29745_RS13195	COG2239	Acts as a magnesium transporter
CDIF29745_RS13200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDIF29745_RS13205	COG0295	cytidine deaminase activity
CDIF29745_RS13210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDIF29745_RS13215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDIF29745_RS13220	COG1702	phosphate starvation-inducible protein PhoH
CDIF29745_RS13240	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CDIF29745_RS13245	COG1610	YqeY-like protein
CDIF29745_RS13250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDIF29745_RS13255	COG0537	adenosine 5'-monophosphoramidase activity
CDIF29745_RS13260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDIF29745_RS13265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDIF29745_RS13270	COG2264	protein methyltransferase activity
CDIF29745_RS13300	COG3842	ATPase activity
CDIF29745_RS13305	COG2508	Transcriptional regulator
CDIF29745_RS13310	COG0477	Major facilitator Superfamily
CDIF29745_RS13325	COG0484	heat shock protein binding
CDIF29745_RS13330	COG0443	Heat shock 70 kDa protein
CDIF29745_RS13335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDIF29745_RS13340	COG1420	regulation of RNA biosynthetic process
CDIF29745_RS13345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDIF29745_RS13350	COG0531	amino acid
CDIF29745_RS13355	COG0617	tRNA 3'-terminal CCA addition
CDIF29745_RS13360	COG0481	GTPase activity
CDIF29745_RS13390	COG0268	Binds directly to 16S ribosomal RNA
CDIF29745_RS13400	COG2333	competence protein COMEC
CDIF29745_RS13400	COG0658	competence protein
CDIF29745_RS13420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDIF29745_RS13425	COG3584	3D domain protein
CDIF29745_RS13425	COG1388	LysM domain
CDIF29745_RS13430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDIF29745_RS13445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29745_RS13450	COG0006	proline dipeptidase activity
CDIF29745_RS13455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS13460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS13465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS13465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDIF29745_RS13465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS13470	COG3711	transcriptional antiterminator
CDIF29745_RS13470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS13475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS13480	COG1482	cell wall glycoprotein biosynthetic process
CDIF29745_RS13485	COG5002	protein histidine kinase activity
CDIF29745_RS13505	COG1555	photosystem II stabilization
CDIF29745_RS13510	COG1686	Belongs to the peptidase S11 family
CDIF29745_RS13520	COG0165	Argininosuccinate lyase
CDIF29745_RS13525	COG0561	phosphatase activity
CDIF29745_RS13530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29745_RS13535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDIF29745_RS13540	COG1876	peptidase activity
CDIF29745_RS13545	COG1309	transcriptional regulator
CDIF29745_RS13550	COG2814	Major facilitator Superfamily
CDIF29745_RS13560	COG4977	sequence-specific DNA binding
CDIF29745_RS13570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS13570	COG1263	PTS System
CDIF29745_RS13575	COG3711	transcriptional antiterminator
CDIF29745_RS13580	COG2190	(PTS) system
CDIF29745_RS13580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS13580	COG1263	PTS System
CDIF29745_RS13585	COG0251	oxidation-reduction process
CDIF29745_RS13590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDIF29745_RS13630	COG0582	viral genome integration into host DNA
CDIF29745_RS13645	COG0495	leucyl-tRNA aminoacylation
CDIF29745_RS13650	COG0799	negative regulation of ribosome biogenesis
CDIF29745_RS13655	COG1713	HD superfamily hydrolase involved in NAD metabolism
CDIF29745_RS13660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDIF29745_RS13665	COG2137	regulation of response to DNA damage stimulus
CDIF29745_RS13670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDIF29745_RS13675	COG1309	transcriptional regulator
CDIF29745_RS13700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDIF29745_RS13710	COG0577	efflux transmembrane transporter activity
CDIF29745_RS13710	COG1136	(ABC) transporter
CDIF29745_RS13720	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS13725	COG0737	Belongs to the 5'-nucleotidase family
CDIF29745_RS13735	COG1234	tRNA 3'-trailer cleavage
CDIF29745_RS13740	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDIF29745_RS13745	COG1823	symporter activity
CDIF29745_RS13770	COG4124	Belongs to the glycosyl hydrolase 26 family
CDIF29745_RS13770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CDIF29745_RS13780	COG0395	ABC-type sugar transport system, permease component
CDIF29745_RS13800	COG4821	SIS domain
CDIF29745_RS13830	COG0742	ribosomal rna small subunit methyltransferase
CDIF29745_RS13835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDIF29745_RS13840	COG1461	Dihydroxyacetone kinase
CDIF29745_RS13845	COG1302	Protein conserved in bacteria
CDIF29745_RS13850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDIF29745_RS13865	COG0789	Transcriptional regulator
CDIF29745_RS13870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS13870	COG3711	transcriptional antiterminator
CDIF29745_RS13875	COG3711	transcriptional antiterminator
CDIF29745_RS13875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS13880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS13885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS13890	COG0383	alpha-mannosidase activity
CDIF29745_RS13915	COG1564	THIamine pyrophosphokinase
CDIF29745_RS13920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDIF29745_RS13925	COG1162	GTPase activity
CDIF29745_RS13930	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29745_RS13935	COG0515	serine threonine protein kinase
CDIF29745_RS13935	COG2815	serine threonine protein kinase
CDIF29745_RS13945	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDIF29745_RS13950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDIF29745_RS13950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDIF29745_RS13955	COG2738	Putative neutral zinc metallopeptidase
CDIF29745_RS13965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDIF29745_RS13970	COG0242	peptide deformylase activity
CDIF29745_RS13975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDIF29745_RS13980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDIF29745_RS13985	COG1758	RNA polymerase activity
CDIF29745_RS13990	COG0194	GDP metabolic process
CDIF29745_RS13995	COG1561	YicC-like family, N-terminal region
CDIF29745_RS14000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDIF29745_RS14010	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CDIF29745_RS14015	COG0488	(ABC) transporter
CDIF29745_RS14025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDIF29745_RS14030	COG0564	pseudouridine synthase activity
CDIF29745_RS14035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDIF29745_RS14045	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDIF29745_RS14050	COG1966	Carbon starvation protein
CDIF29745_RS14055	COG3279	Response regulator of the LytR AlgR family
CDIF29745_RS14060	COG3275	phosphorelay sensor kinase activity
CDIF29745_RS14095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDIF29745_RS14100	COG0531	amino acid
CDIF29745_RS14105	COG0006	proline dipeptidase activity
CDIF29745_RS14110	COG1307	EDD domain protein, DegV family
CDIF29745_RS14125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29745_RS14130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDIF29745_RS14140	COG2302	S4 RNA-binding domain
CDIF29745_RS14150	COG1799	cell septum assembly
CDIF29745_RS14155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDIF29745_RS14175	COG3830	Belongs to the UPF0237 family
CDIF29745_RS14185	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDIF29745_RS14190	COG2271	Major facilitator Superfamily
CDIF29745_RS14195	COG0531	amino acid
CDIF29745_RS14200	COG0006	proline dipeptidase activity
CDIF29745_RS14210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDIF29745_RS14215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDIF29745_RS14220	COG1160	GTP binding
CDIF29745_RS14245	COG5002	protein histidine kinase activity
CDIF29745_RS14250	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS14260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDIF29745_RS14265	COG1873	PFAM PRC-barrel domain
CDIF29745_RS14270	COG1191	sigma factor activity
CDIF29745_RS14275	COG1191	sigma factor activity
CDIF29745_RS14290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDIF29745_RS14295	COG3856	small basic protein
CDIF29745_RS14315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29745_RS14320	COG0772	Belongs to the SEDS family
CDIF29745_RS14325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDIF29745_RS14330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDIF29745_RS14335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDIF29745_RS14340	COG0768	penicillin binding
CDIF29745_RS14350	COG0275	rRNA processing
CDIF29745_RS14355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDIF29745_RS14360	COG0612	Peptidase, M16
CDIF29745_RS14370	COG0012	GTP binding
CDIF29745_RS14380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDIF29745_RS14390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS14390	COG1263	PTS System
CDIF29745_RS14390	COG2190	(PTS) system
CDIF29745_RS14395	COG3711	transcriptional antiterminator
CDIF29745_RS14400	COG0025	NhaP-type Na H and K H
CDIF29745_RS14405	COG4608	Belongs to the ABC transporter superfamily
CDIF29745_RS14410	COG0444	Belongs to the ABC transporter superfamily
CDIF29745_RS14420	COG0601	transmembrane transport
CDIF29745_RS14425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDIF29745_RS14430	COG0583	DNA-binding transcription factor activity
CDIF29745_RS14435	COG0183	Belongs to the thiolase family
CDIF29745_RS14440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDIF29745_RS14450	COG1028	Short-chain dehydrogenase reductase Sdr
CDIF29745_RS14455	COG2610	gluconate transmembrane transporter activity
CDIF29745_RS14460	COG2340	Cysteine-rich secretory protein family
CDIF29745_RS14475	COG4869	propanediol catabolic process
CDIF29745_RS14510	COG2081	HI0933 family
CDIF29745_RS14515	COG0671	phosphoesterase, PA-phosphatase related
CDIF29745_RS14525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29745_RS14540	COG2502	aspartate--ammonia ligase
CDIF29745_RS14545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29745_RS14550	COG1473	amidohydrolase
CDIF29745_RS14560	COG3366	ferrous iron transmembrane transporter activity
CDIF29745_RS14585	COG2252	PERMEase
CDIF29745_RS14590	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29745_RS14600	COG2271	Major facilitator Superfamily
CDIF29745_RS14620	COG0583	DNA-binding transcription factor activity
CDIF29745_RS14630	COG1376	ErfK ybiS ycfS ynhG family protein
CDIF29745_RS14635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDIF29745_RS14640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDIF29745_RS14665	COG4509	Sortase family
CDIF29745_RS14685	COG0726	polysaccharide deacetylase
CDIF29745_RS14690	COG3069	C4-dicarboxylate transmembrane transporter activity
CDIF29745_RS14695	COG0642	Histidine kinase
CDIF29745_RS14695	COG5002	protein histidine kinase activity
CDIF29745_RS14700	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS14715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDIF29745_RS14720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDIF29745_RS14740	COG1937	Protein conserved in bacteria
CDIF29745_RS14755	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29745_RS14760	COG1757	Na H antiporter
CDIF29745_RS14770	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS14770	COG2247	cell wall binding repeat
CDIF29745_RS14775	COG0583	DNA-binding transcription factor activity
CDIF29745_RS14780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDIF29745_RS14790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDIF29745_RS14795	COG0124	histidyl-tRNA synthetase
CDIF29745_RS14800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDIF29745_RS14805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDIF29745_RS14810	COG1490	D-aminoacyl-tRNA deacylase activity
CDIF29745_RS14815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDIF29745_RS14820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDIF29745_RS14825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDIF29745_RS14825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDIF29745_RS14870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS14895	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS14900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDIF29745_RS14910	COG0561	phosphatase activity
CDIF29745_RS14915	COG1316	TRANSCRIPTIONal
CDIF29745_RS14920	COG1316	TRANSCRIPTIONal
CDIF29745_RS14925	COG1649	PFAM Uncharacterised BCR, COG1649
CDIF29745_RS14940	COG0438	transferase activity, transferring glycosyl groups
CDIF29745_RS14945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDIF29745_RS14950	COG1215	transferase activity, transferring glycosyl groups
CDIF29745_RS14960	COG1215	transferase activity, transferring glycosyl groups
CDIF29745_RS14965	COG1215	transferase activity, transferring glycosyl groups
CDIF29745_RS14965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDIF29745_RS14970	COG1216	Glycosyl transferase, family 2
CDIF29745_RS14990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDIF29745_RS14995	COG0728	peptidoglycan biosynthetic process
CDIF29745_RS15000	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS15000	COG2247	cell wall binding repeat
CDIF29745_RS15005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDIF29745_RS15010	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS15025	COG2247	cell wall binding repeat
CDIF29745_RS15025	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS15035	COG2246	polysaccharide biosynthetic process
CDIF29745_RS15040	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS15040	COG2247	cell wall binding repeat
CDIF29745_RS15055	COG0653	protein targeting
CDIF29745_RS15090	COG2247	cell wall binding repeat
CDIF29745_RS15090	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS15110	COG0343	queuine tRNA-ribosyltransferase activity
CDIF29745_RS15120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDIF29745_RS15125	COG2255	four-way junction helicase activity
CDIF29745_RS15130	COG0632	four-way junction helicase activity
CDIF29745_RS15135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDIF29745_RS15160	COG2610	gluconate transmembrane transporter activity
CDIF29745_RS15165	COG2084	Dehydrogenase
CDIF29745_RS15185	COG1132	(ABC) transporter
CDIF29745_RS15205	COG0700	Nucleoside recognition
CDIF29745_RS15210	COG3366	ferrous iron transmembrane transporter activity
CDIF29745_RS15215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS15245	COG0436	Aminotransferase
CDIF29745_RS15250	COG0697	spore germination
CDIF29745_RS15265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDIF29745_RS15280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDIF29745_RS15285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CDIF29745_RS15290	COG1473	amidohydrolase
CDIF29745_RS15295	COG3949	Membrane
CDIF29745_RS15310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDIF29745_RS15325	COG0604	alcohol dehydrogenase
CDIF29745_RS15335	COG1592	Rubrerythrin
CDIF29745_RS15340	COG0789	Transcriptional regulator
CDIF29745_RS15350	COG1664	Polymer-forming cytoskeletal
CDIF29745_RS15355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDIF29745_RS15355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29745_RS15360	COG1349	DNA-binding transcription factor activity
CDIF29745_RS15365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDIF29745_RS15370	COG1696	Membrane protein involved in D-alanine export
CDIF29745_RS15375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDIF29745_RS15385	COG0673	inositol 2-dehydrogenase activity
CDIF29745_RS15395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29745_RS15400	COG1253	flavin adenine dinucleotide binding
CDIF29745_RS15405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDIF29745_RS15425	COG3829	transcription factor binding
CDIF29745_RS15425	COG3290	protein histidine kinase activity
CDIF29745_RS15430	COG2267	carboxylic ester hydrolase activity
CDIF29745_RS15440	COG0312	modulator of DNA gyrase
CDIF29745_RS15445	COG0312	modulator of DNA gyrase
CDIF29745_RS15470	COG2721	sulfolactate sulfo-lyase activity
CDIF29745_RS15485	COG1120	ATPase activity
CDIF29745_RS15490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29745_RS15495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29745_RS15510	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29745_RS15515	COG3394	polysaccharide catabolic process
CDIF29745_RS15520	COG1486	melibiose metabolic process
CDIF29745_RS15525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS15535	COG2188	Transcriptional regulator
CDIF29745_RS15540	COG0534	Mate efflux family protein
CDIF29745_RS15545	COG2199	diguanylate cyclase activity
CDIF29745_RS15550	COG1178	ABC-type Fe3 transport system permease component
CDIF29745_RS15555	COG3842	ATPase activity
CDIF29745_RS15560	COG1840	ABC-type Fe3 transport system, periplasmic component
CDIF29745_RS15565	COG1394	ATPase activity, coupled to movement of substances
CDIF29745_RS15570	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CDIF29745_RS15575	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CDIF29745_RS15590	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CDIF29745_RS15595	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDIF29745_RS15600	COG1269	ATP hydrolysis coupled proton transport
CDIF29745_RS15625	COG3300	MHYT domain
CDIF29745_RS15625	COG5001	Diguanylate cyclase
CDIF29745_RS15630	COG1012	belongs to the aldehyde dehydrogenase family
CDIF29745_RS15630	COG1454	alcohol dehydrogenase
CDIF29745_RS15640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDIF29745_RS15650	COG0318	PFAM AMP-dependent synthetase and ligase
CDIF29745_RS15655	COG0183	Belongs to the thiolase family
CDIF29745_RS15660	COG1268	BioY protein
CDIF29745_RS15675	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CDIF29745_RS15690	COG1203	CRISPR-associated helicase, Cas3
CDIF29745_RS15720	COG0577	efflux transmembrane transporter activity
CDIF29745_RS15725	COG1136	(ABC) transporter
CDIF29745_RS15730	COG1968	undecaprenyl-diphosphatase activity
CDIF29745_RS15735	COG2205	protein histidine kinase activity
CDIF29745_RS15740	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS15755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDIF29745_RS15770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDIF29745_RS15775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDIF29745_RS15785	COG1120	ATPase activity
CDIF29745_RS15790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDIF29745_RS15800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29745_RS15805	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDIF29745_RS15830	COG1454	alcohol dehydrogenase
CDIF29745_RS15835	COG1376	ErfK ybiS ycfS ynhG family protein
CDIF29745_RS15845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDIF29745_RS15850	COG0785	Cytochrome C biogenesis protein
CDIF29745_RS15855	COG1733	regulation of RNA biosynthetic process
CDIF29745_RS15860	COG0383	alpha-mannosidase activity
CDIF29745_RS15865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS15870	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS15875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS15875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS15875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS15880	COG3711	transcriptional antiterminator
CDIF29745_RS15880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS15885	COG4975	Glucose uptake
CDIF29745_RS15920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDIF29745_RS15935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDIF29745_RS15935	COG0517	IMP dehydrogenase activity
CDIF29745_RS15940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29745_RS15945	COG1263	PTS System
CDIF29745_RS15945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS15950	COG3711	transcriptional antiterminator
CDIF29745_RS15955	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDIF29745_RS15960	COG3118	belongs to the thioredoxin family
CDIF29745_RS15970	COG0384	phenazine biosynthesis protein PhzF
CDIF29745_RS15990	COG0542	response to heat
CDIF29745_RS16000	COG2267	carboxylic ester hydrolase activity
CDIF29745_RS16015	COG1737	Transcriptional regulator
CDIF29745_RS16020	COG2971	BadF BadG BcrA BcrD
CDIF29745_RS16025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDIF29745_RS16035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS16050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDIF29745_RS16060	COG0642	Histidine kinase
CDIF29745_RS16075	COG1136	(ABC) transporter
CDIF29745_RS16085	COG2190	(PTS) system
CDIF29745_RS16100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16100	COG1263	PTS System
CDIF29745_RS16115	COG2115	Belongs to the xylose isomerase family
CDIF29745_RS16120	COG1070	Carbohydrate kinase
CDIF29745_RS16135	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16135	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16140	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29745_RS16170	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDIF29745_RS16195	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDIF29745_RS16200	COG0191	fructose-bisphosphate aldolase activity
CDIF29745_RS16205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16220	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS16230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS16240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16240	COG2213	PTS system mannitol-specific
CDIF29745_RS16245	COG1929	Belongs to the glycerate kinase type-1 family
CDIF29745_RS16250	COG0383	alpha-mannosidase activity
CDIF29745_RS16255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16265	COG3394	polysaccharide catabolic process
CDIF29745_RS16270	COG2190	(PTS) system
CDIF29745_RS16270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16270	COG1263	PTS System
CDIF29745_RS16275	COG2188	Transcriptional regulator
CDIF29745_RS16280	COG0366	Alpha amylase catalytic
CDIF29745_RS16325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CDIF29745_RS16340	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS16345	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS16350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16350	COG2190	(PTS) system
CDIF29745_RS16350	COG1263	PTS System
CDIF29745_RS16355	COG3711	transcriptional antiterminator
CDIF29745_RS16365	COG1288	antiporter activity
CDIF29745_RS16370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16370	COG1263	PTS System
CDIF29745_RS16375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDIF29745_RS16385	COG0561	phosphatase activity
CDIF29745_RS16410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDIF29745_RS16445	COG1674	ftsk spoiiie
CDIF29745_RS16450	COG2946	Replication initiation factor
CDIF29745_RS16465	COG1396	sequence-specific DNA binding
CDIF29745_RS16500	COG0741	lytic transglycosylase activity
CDIF29745_RS16500	COG0791	NLP P60 protein
CDIF29745_RS16515	COG1131	(ABC) transporter
CDIF29745_RS16575	COG1192	Involved in chromosome partitioning
CDIF29745_RS16620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16620	COG3711	transcriptional antiterminator
CDIF29745_RS16625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDIF29745_RS16630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDIF29745_RS16635	COG0205	6-phosphofructokinase activity
CDIF29745_RS16645	COG1473	amidohydrolase
CDIF29745_RS16650	COG1473	amidohydrolase
CDIF29745_RS16660	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS16665	COG1263	PTS System
CDIF29745_RS16665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16665	COG2190	(PTS) system
CDIF29745_RS16680	COG1819	glycosyl
CDIF29745_RS16685	COG3620	sequence-specific DNA binding
CDIF29745_RS16700	COG0640	Transcriptional regulator
CDIF29745_RS16710	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS16715	COG2190	(PTS) system
CDIF29745_RS16715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16715	COG1263	PTS System
CDIF29745_RS16720	COG3711	transcriptional antiterminator
CDIF29745_RS16730	COG1136	(ABC) transporter
CDIF29745_RS16730	COG0577	efflux transmembrane transporter activity
CDIF29745_RS16735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS16735	COG1263	PTS System
CDIF29745_RS16740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDIF29745_RS16750	COG2723	6-phospho-beta-galactosidase activity
CDIF29745_RS16760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16765	COG3711	transcriptional antiterminator
CDIF29745_RS16770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS16770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDIF29745_RS16775	COG0191	fructose-bisphosphate aldolase activity
CDIF29745_RS16795	COG0693	protein deglycase activity
CDIF29745_RS16815	COG1136	(ABC) transporter
CDIF29745_RS16855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDIF29745_RS16870	COG1074	ATP-dependent DNA helicase activity
CDIF29745_RS16895	COG0582	viral genome integration into host DNA
CDIF29745_RS16910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDIF29745_RS16945	COG0557	exoribonuclease II activity
CDIF29745_RS16960	COG1881	PFAM PEBP family protein
CDIF29745_RS16980	COG0148	phosphopyruvate hydratase activity
CDIF29745_RS16985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDIF29745_RS16990	COG0149	triose-phosphate isomerase activity
CDIF29745_RS16995	COG0126	phosphoglycerate kinase activity
CDIF29745_RS17005	COG2390	Transcriptional regulator
CDIF29745_RS17010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDIF29745_RS17015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDIF29745_RS17025	COG0167	dihydroorotate dehydrogenase activity
CDIF29745_RS17035	COG0402	S-adenosylhomocysteine deaminase activity
CDIF29745_RS17040	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CDIF29745_RS17060	COG3829	transcription factor binding
CDIF29745_RS17065	COG0251	oxidation-reduction process
CDIF29745_RS17080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDIF29745_RS17085	COG0789	Transcriptional regulator
CDIF29745_RS17095	COG2247	cell wall binding repeat
CDIF29745_RS17095	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDIF29745_RS17105	COG2207	Transcriptional regulator
CDIF29745_RS17110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29745_RS17120	COG0789	Transcriptional regulator
CDIF29745_RS17145	COG2770	Histidine kinase
CDIF29745_RS17145	COG2205	protein histidine kinase activity
CDIF29745_RS17150	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS17155	COG0706	membrane insertase activity
CDIF29745_RS17165	COG0778	Nitroreductase
CDIF29745_RS17175	COG0534	Mate efflux family protein
CDIF29745_RS17200	COG2226	methyltransferase
CDIF29745_RS17220	COG1732	Glycine betaine
CDIF29745_RS17225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDIF29745_RS17235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDIF29745_RS17240	COG2226	methyltransferase
CDIF29745_RS17250	COG1473	amidohydrolase
CDIF29745_RS17255	COG1760	l-serine dehydratase
CDIF29745_RS17265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDIF29745_RS17270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29745_RS17275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDIF29745_RS17280	COG2171	N-acyltransferase activity
CDIF29745_RS17290	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDIF29745_RS17300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDIF29745_RS17305	COG3681	Belongs to the UPF0597 family
CDIF29745_RS17315	COG3829	transcription factor binding
CDIF29745_RS17320	COG2226	methyltransferase
CDIF29745_RS17345	COG0252	asparaginase activity
CDIF29745_RS17345	COG5275	peptidyl-tyrosine sulfation
CDIF29745_RS17350	COG0252	asparaginase activity
CDIF29745_RS17350	COG5275	peptidyl-tyrosine sulfation
CDIF29745_RS17365	COG5275	peptidyl-tyrosine sulfation
CDIF29745_RS17365	COG0252	asparaginase activity
CDIF29745_RS17385	COG4656	Part of a membrane complex involved in electron transport
CDIF29745_RS17395	COG0726	polysaccharide deacetylase
CDIF29745_RS17420	COG0285	dihydrofolate synthase activity
CDIF29745_RS17430	COG3279	Response regulator of the LytR AlgR family
CDIF29745_RS17435	COG0525	valine-tRNA ligase activity
CDIF29745_RS17445	COG0726	polysaccharide deacetylase
CDIF29745_RS17460	COG0704	Plays a role in the regulation of phosphate uptake
CDIF29745_RS17465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDIF29745_RS17470	COG0581	inorganic phosphate transmembrane transporter activity
CDIF29745_RS17475	COG0573	inorganic phosphate transmembrane transporter activity
CDIF29745_RS17495	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS17500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDIF29745_RS17505	COG1164	Oligoendopeptidase f
CDIF29745_RS17510	COG1285	pathogenesis
CDIF29745_RS17535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CDIF29745_RS17540	COG3716	PTS system mannose fructose sorbose family IID component
CDIF29745_RS17545	COG3715	PTS system
CDIF29745_RS17550	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS17550	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS17555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDIF29745_RS17555	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDIF29745_RS17565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDIF29745_RS17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDIF29745_RS17585	COG0166	Belongs to the GPI family
CDIF29745_RS17595	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CDIF29745_RS17610	COG3012	SEC-C Motif Domain Protein
CDIF29745_RS17610	COG1405	negative regulation of cell septum assembly
CDIF29745_RS17635	COG1459	type II secretion system
CDIF29745_RS17640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDIF29745_RS17655	COG2814	Major facilitator Superfamily
CDIF29745_RS17660	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDIF29745_RS17665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDIF29745_RS17675	COG2059	Chromate
CDIF29745_RS17680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDIF29745_RS17685	COG0740	serine-type endopeptidase activity
CDIF29745_RS17690	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDIF29745_RS17705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDIF29745_RS17725	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29745_RS17725	COG0493	'glutamate synthase
CDIF29745_RS17735	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDIF29745_RS17745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDIF29745_RS17780	COG1131	(ABC) transporter
CDIF29745_RS17810	COG3279	Response regulator of the LytR AlgR family
CDIF29745_RS17840	COG0457	Tetratricopeptide repeat
CDIF29745_RS17840	COG0463	Glycosyl transferase, family 2
CDIF29745_RS17855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS17865	COG0778	Nitroreductase
CDIF29745_RS17870	COG1733	regulation of RNA biosynthetic process
CDIF29745_RS17875	COG0693	protein deglycase activity
CDIF29745_RS17880	COG1522	sequence-specific DNA binding
CDIF29745_RS17885	COG0488	(ABC) transporter
CDIF29745_RS17890	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS17910	COG4555	ABC transporter
CDIF29745_RS17915	COG5001	Diguanylate cyclase
CDIF29745_RS17975	COG5002	protein histidine kinase activity
CDIF29745_RS17990	COG1136	(ABC) transporter
CDIF29745_RS18000	COG0348	domain, Protein
CDIF29745_RS18000	COG3901	Regulator of nitric oxide reductase transcription
CDIF29745_RS18010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDIF29745_RS18095	COG3103	Sh3 type 3 domain protein
CDIF29745_RS18095	COG1388	LysM domain
CDIF29745_RS18095	COG0791	NLP P60 protein
CDIF29745_RS18130	COG2207	Transcriptional regulator
CDIF29745_RS18130	COG3708	Transcriptional regulator
CDIF29745_RS18165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDIF29745_RS18195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDIF29745_RS18215	COG0745	RESPONSE REGULATOR receiver
CDIF29745_RS18220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDIF29745_RS18240	COG0791	NLP P60 protein
CDIF29745_RS18240	COG0741	lytic transglycosylase activity
CDIF29745_RS18290	COG2946	Replication initiation factor
CDIF29745_RS18295	COG1674	ftsk spoiiie
CDIF29745_RS18335	COG0205	6-phosphofructokinase activity
CDIF29745_RS18345	COG1481	regulation of sporulation
CDIF29745_RS18360	COG1660	Displays ATPase and GTPase activities
CDIF29745_RS18370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDIF29745_RS18375	COG2116	formate transmembrane transporter activity
CDIF29745_RS18380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDIF29745_RS18410	COG0322	excinuclease ABC activity
CDIF29745_RS18420	COG0556	nucleotide-excision repair
CDIF29745_RS18430	COG1653	transport
CDIF29745_RS18440	COG1175	transmembrane transport
CDIF29745_RS18445	COG3842	ATPase activity
CDIF29745_RS18465	COG1648	precorrin-2 dehydrogenase activity
CDIF29745_RS18465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDIF29745_RS18470	COG0113	porphobilinogen synthase activity
CDIF29745_RS18480	COG0181	hydroxymethylbilane synthase activity
CDIF29745_RS18490	COG2099	Precorrin-6x reductase
CDIF29745_RS18520	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CDIF29745_RS18535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDIF29745_RS18545	COG1797	cobyrinic acid a,c-diamide synthase activity
CDIF29745_RS18550	COG1492	cobalamin metabolic process
CDIF29745_RS18555	COG0406	alpha-ribazole phosphatase activity
CDIF29745_RS18560	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDIF29745_RS18565	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
CDIF29745_RS18570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDIF29745_RS18590	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDIF29745_RS18605	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS18610	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29745_RS18615	COG1363	Peptidase, m42
CDIF29745_RS18620	COG3711	transcriptional antiterminator
CDIF29745_RS18625	COG0191	fructose-bisphosphate aldolase activity
CDIF29745_RS18630	COG2222	sugar isomerase
CDIF29745_RS18645	COG2188	Transcriptional regulator
CDIF29745_RS18655	COG3314	Sporulation integral membrane protein YlbJ
CDIF29745_RS18670	COG1414	Transcriptional regulator
CDIF29745_RS18680	COG0793	Belongs to the peptidase S41A family
CDIF29745_RS18680	COG3409	Peptidoglycan-binding domain 1 protein
CDIF29745_RS18685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDIF29745_RS18695	COG3949	Membrane
CDIF29745_RS18700	COG3958	Transketolase
CDIF29745_RS18705	COG3959	Transketolase, thiamine diphosphate binding domain
CDIF29745_RS18710	COG2337	Toxic component of a toxin-antitoxin (TA) module
CDIF29745_RS18730	COG0516	GMP reductase activity
CDIF29745_RS18730	COG0517	IMP dehydrogenase activity
CDIF29745_RS18735	COG0736	holo-[acyl-carrier-protein] synthase activity
CDIF29745_RS18740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDIF29745_RS18745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDIF29745_RS18750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDIF29745_RS18755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDIF29745_RS18760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDIF29745_RS18765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDIF29745_RS18770	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDIF29745_RS18800	COG3608	succinylglutamate desuccinylase aspartoacylase
CDIF29745_RS18800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDIF29745_RS18805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDIF29745_RS18810	COG0698	ribose 5-phosphate isomerase
CDIF29745_RS18820	COG0009	L-threonylcarbamoyladenylate synthase
CDIF29745_RS18830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDIF29745_RS18835	COG2890	protein-(glutamine-N5) methyltransferase activity
CDIF29745_RS18840	COG3872	metal-dependent enzyme
CDIF29745_RS18845	COG0254	rRNA binding
CDIF29745_RS18850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDIF29745_RS18855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDIF29745_RS18865	COG2208	phosphoserine phosphatase activity
CDIF29745_RS18870	COG0248	Ppx GppA phosphatase
CDIF29745_RS18890	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDIF29745_RS18900	COG3956	TIGRFAM MazG family protein
CDIF29745_RS18905	COG2244	polysaccharide biosynthetic process
CDIF29745_RS18910	COG2002	toxin-antitoxin pair type II binding
CDIF29745_RS18915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDIF29745_RS18920	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDIF29745_RS18925	COG0193	aminoacyl-tRNA hydrolase activity
CDIF29745_RS18975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDIF29745_RS18990	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDIF29745_RS18995	COG2088	sporulation resulting in formation of a cellular spore
CDIF29745_RS19000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDIF29745_RS19005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDIF29745_RS19015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDIF29745_RS19020	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDIF29745_RS19030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDIF29745_RS19035	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDIF29745_RS19040	COG1840	ABC-type Fe3 transport system, periplasmic component
CDIF29745_RS19050	COG1840	ABC-type Fe3 transport system, periplasmic component
CDIF29745_RS19060	COG3842	ATPase activity
CDIF29745_RS19065	COG0613	PHP domain protein
CDIF29745_RS19070	COG3454	Phosphonate metabolism
CDIF29745_RS19075	COG4778	phosphonate C-P lyase system protein PhnL
CDIF29745_RS19080	COG4107	phosphonate C-P lyase system protein PhnK
CDIF29745_RS19085	COG3627	carbon phosphorus lyase activity
CDIF29745_RS19105	COG0084	hydrolase, TatD family'
CDIF29745_RS19110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29745_RS19110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDIF29745_RS19115	COG0700	Nucleoside recognition
CDIF29745_RS19125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDIF29745_RS19130	COG1522	sequence-specific DNA binding
CDIF29745_RS19135	COG0617	tRNA 3'-terminal CCA addition
CDIF29745_RS19140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDIF29745_RS19145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDIF29745_RS19150	COG1774	PSP1 C-terminal conserved region
CDIF29745_RS19155	COG0470	DNA polymerase III
CDIF29745_RS19160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDIF29745_RS19165	COG1982	Orn Lys Arg decarboxylase major
CDIF29745_RS19170	COG2155	Conserved Protein
CDIF29745_RS19195	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDIF29745_RS19200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDIF29745_RS19210	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDIF29745_RS19220	COG3191	aminopeptidase activity
CDIF29745_RS19230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDIF29745_RS19235	COG0037	tRNA processing
CDIF29745_RS19245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDIF29745_RS19260	COG1802	Transcriptional regulator
CDIF29745_RS19265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDIF29745_RS19295	COG0653	protein targeting
CDIF29745_RS19320	COG2271	Major facilitator Superfamily
CDIF29745_RS19325	COG0626	cystathionine gamma-synthase activity
CDIF29745_RS19350	COG0564	pseudouridine synthase activity
CDIF29745_RS19355	COG0789	Transcriptional regulator
CDIF29745_RS19355	COG4978	Transcriptional regulator
CDIF29745_RS19365	COG0577	efflux transmembrane transporter activity
CDIF29745_RS19365	COG1136	(ABC) transporter
CDIF29745_RS19370	COG5002	protein histidine kinase activity
CDIF29745_RS19390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDIF29745_RS19400	COG0284	orotidine-5'-phosphate decarboxylase activity
CDIF29745_RS19420	COG1410	methionine synthase
CDIF29745_RS19420	COG0646	methionine synthase
CDIF29745_RS19430	COG1854	S-ribosylhomocysteine lyase activity
CDIF29745_RS19445	COG1876	peptidase activity
CDIF29745_RS19450	COG0037	tRNA processing
CDIF29745_RS19455	COG1408	metallophosphoesterase
CDIF29745_RS19470	COG1141	Ferredoxin
CDIF29745_RS19475	COG3964	amidohydrolase
CDIF29745_RS19485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDIF29745_RS19495	COG0346	lactoylglutathione lyase activity
CDIF29745_RS19500	COG0534	Mate efflux family protein
CDIF29745_RS19515	COG0789	Transcriptional regulator
CDIF29745_RS19515	COG4978	Transcriptional regulator
CDIF29745_RS19525	COG5504	Zn-dependent protease
CDIF29745_RS19535	COG0519	Catalyzes the synthesis of GMP from XMP
CDIF29745_RS19545	COG1357	PFAM Pentapeptide repeats (8 copies)
CDIF29745_RS19550	COG2824	Alkylphosphonate utilization operon protein PhnA
CDIF29745_RS19555	COG0577	efflux transmembrane transporter activity
CDIF29745_RS19555	COG1136	(ABC) transporter
CDIF29745_RS19565	COG5001	Diguanylate cyclase
CDIF29745_RS19565	COG3447	MASE1 domain protein
CDIF29745_RS19565	COG5002	protein histidine kinase activity
CDIF29745_RS19570	COG0352	thiamine-phosphate diphosphorylase activity
CDIF29745_RS19575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDIF29745_RS19580	COG0517	IMP dehydrogenase activity
CDIF29745_RS19580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDIF29745_RS19610	COG0789	Transcriptional regulator
CDIF29745_RS19640	COG0583	DNA-binding transcription factor activity
CDIF29745_RS19660	COG3964	amidohydrolase
CDIF29745_RS19670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS19675	COG2188	Transcriptional regulator
CDIF29745_RS19680	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDIF29745_RS19685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS19690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDIF29745_RS19695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDIF29745_RS19700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDIF29745_RS19715	COG1484	DNA-dependent DNA replication
CDIF29745_RS19740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDIF29745_RS19750	COG0305	Participates in initiation and elongation during chromosome replication
CDIF29745_RS19755	COG0359	binds to the 23S rRNA
CDIF29745_RS19760	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CDIF29745_RS19775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDIF29745_RS19780	COG0629	single-stranded DNA binding
CDIF29745_RS19785	COG0360	Binds together with S18 to 16S ribosomal RNA
CDIF29745_RS19790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDIF29745_RS19805	COG0425	Belongs to the sulfur carrier protein TusA family
CDIF29745_RS19820	COG1104	cysteine desulfurase activity
CDIF29745_RS19825	COG1475	DNA binding
CDIF29745_RS19830	COG1192	Involved in chromosome partitioning
CDIF29745_RS19835	COG1475	DNA binding
CDIF29745_RS19840	COG0357	Ribosomal RNA small subunit methyltransferase G
CDIF29745_RS19845	COG0445	tRNA wobble uridine modification
CDIF29745_RS19850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDIF29745_RS19855	COG1847	R3H domain protein
CDIF29745_RS19860	COG0706	membrane insertase activity
CDIF29745_RS19865	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDIF29745_RS19870	COG0594	ribonuclease P activity
CDIF29745_RS19875	COG0230	Belongs to the bacterial ribosomal protein bL34 family